CN105466097B - Heterogeneity biological eyeball cold storage plant - Google Patents

Heterogeneity biological eyeball cold storage plant Download PDF

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Publication number
CN105466097B
CN105466097B CN201610030578.0A CN201610030578A CN105466097B CN 105466097 B CN105466097 B CN 105466097B CN 201610030578 A CN201610030578 A CN 201610030578A CN 105466097 B CN105466097 B CN 105466097B
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China
Prior art keywords
refrigerated cabinet
eyeball
memory plane
cold storage
heterogeneity biological
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CN201610030578.0A
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Chinese (zh)
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CN105466097A (en
Inventor
杨越雄
胡红霞
覃瑜华
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GUANGZHOU ZHONGDA MEDICAL INSTRUMENT CO Ltd
Guangzhou Zhongda Nansha Technology Innovation Industrial Park Co Ltd
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GUANGZHOU ZHONGDA MEDICAL INSTRUMENT CO Ltd
Guangzhou Zhongda Nansha Technology Innovation Industrial Park Co Ltd
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    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/02Devices using other cold materials; Devices using cold-storage bodies using ice, e.g. ice-boxes
    • F25D3/06Movable containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D25/00Charging, supporting, and discharging the articles to be cooled
    • F25D25/02Charging, supporting, and discharging the articles to be cooled by shelves
    • F25D25/024Slidable shelves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2303/00Details of devices using other cold materials; Details of devices using cold-storage bodies
    • F25D2303/08Devices using cold storage material, i.e. ice or other freezable liquid
    • F25D2303/082Devices using cold storage material, i.e. ice or other freezable liquid disposed in a cold storage element not forming part of a container for products to be cooled, e.g. ice pack or gel accumulator

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a kind of heterogeneity biological eyeball cold storage plants, memory plane is placed in refrigerated cabinet, memory plane is equipped with multiple hemispherical grooves, a heterogeneity biological eyeball is placed in each hemispherical groove, it will not cause the mutual pollution between eyeball, it is indeformable without extruding between adjacent eyeball, it is not damaged to the quality of eyeball, do not influence the cut quality of heterogenic cornea.And the memory plane slidably slides in the refrigerated cabinet, therefore, provides convenience for the access of heterogeneity biological eyeball;Memory plane is removably fixed in refrigerated cabinet, convenient for the memory plane is removed cleaning and to the cleaning inside refrigerated cabinet.The icehouse of formation is convenient for the independent storage of ice bag, keeps apart with biological eyeball, avoids cross-infection.

Description

Heterogeneity biological eyeball cold storage plant
Technical field
The present invention relates to biological cornea technical fields, and in particular to for the heterogeneity biological eyeball cold storage plant of transport.
Background technology
Keratonosus is the second diseases causing blindness in global range, and corneal transplantation is the current treatment the only effective side of corneal blindness Method.Annual China waits the patient of corneal transplantation probably to have more than 30 ten thousand, and positive the becoming of rising year by year of presenting of this number Gesture.Corneal transplantation is the optimal selection of clinical treatment keratonosus, but China's donor's cornea lacks, according to statistics, annual China The corneal graft only 7,000 or so that major ophthalmologic hospital is completed.The wretched insufficiency of cornea of the same race promotes people continuous The new material that can substitute cornea of the same race is found in research, makes a general survey of the research history of artificial cornea, the glass no matter occurred earliest Cornea or the macromolecule cornea for being applied to clinic now, suffer from such as simple in structure, poor biocompatibility, degradable etc. Shortcoming.Substantial amounts of research is concentrated mainly in cell hetero stroma of cornea material and engineered corneal material this two class. Up to the present, this one kind of cell hetero stroma of cornea material is gone to make a breakthrough.Cell hetero stroma of cornea mistake is gone in production Cheng Zhong, inventor have found that, to storing there is no more stringent mode for heterogeneity biological eyeball, heterogeneity biological cornea is being cut Front and rear eyeball is deposited in unified vial, easily causes the quality for the cornea that pollution effect is finally cut, and inconvenient It is cleaned in vial.
The content of the invention
The purpose of the present invention is avoid above-mentioned technical problem provide it is a kind of be not easy to pollute, to the eyeball of storage without extruding Heterogeneity biological eyeball cold storage plant.
In order to solve the above technical problems, the embodiment of the present invention the technical solution adopted is that, heterogeneity biological eyeball cold storage plant, It is used to place the memory plane of heterogeneity biological eyeball including refrigerated cabinet, polylith;The memory plane is located in the refrigerated cabinet, with The refrigerated cabinet is removably slidably connected;The hemispherical that the memory plane is equipped with multiple storage heterogeneity biological eyeballs is recessed Slot.
Preferably, two pieces of isolation boards are further included, the both sides of upper surface and the both sides pair of lower surface in the refrigerated cabinet The card slot of the fixed isolation board should be equipped with;One isolation board is fixed on the card slot of homonymy, with the refrigerated cabinet Madial wall formed storage ice bag icehouse.
Preferably, the isolation board be equipped with the matched fixed groove track of the memory plane, the two of the isolation board The fixed groove track is inserted at end, is fixed on isolation board.
Preferably, the isolation board is equipped with regularly arranged hole.
Preferably, the refrigerated cabinet sets Packed case lid and fixing buckle, the case lid is closed when on refrigerated cabinet It is fixed with the fixing buckle.
Preferably, the length of the refrigerated cabinet is 40cm~50cm, width is 36cm~45cm, be highly 35cm~ 40cm;The length of the icehouse is 40cm~50cm, width is 3cm~8cm, is highly 35cm~40cm.
Preferably, the length of the refrigerated cabinet is 45cm, width 44cm, is highly 39cm;The length of the icehouse It spends for 45cm, width 5cm, be highly 39cm.
Preferably, the fixed groove track on an isolation board is equipped with 7.
Preferably, the top of the refrigerated cabinet is equipped with carrying buckle.
When accessing eyeball, case lid is opened, directly extracts or promote the memory plane out, before use, moist heat sterilization is carried out, Then the immersion for 12h being carried out in 65 DEG C of 3% hydrogen peroxide goes to be heat-treated, and places into injection physiological saline and is impregnated; The cold storage plant from injection physiological saline is taken out during use, the note of a small amount of added with antibiotic is injected in hemispherical groove It penetrates and uses physiological saline.
Compared with correlation technique, the advantageous effect of the embodiment of the present invention is that an embodiment of the present invention provides a kind of lifes of xenogenesis Object eyeball cold storage plant, places memory plane in refrigerated cabinet, and memory plane is removably fixed in refrigerated cabinet, convenient for inciting somebody to action The memory plane removes cleaning and to the cleaning inside refrigerated cabinet;It is slidably slided in the refrigerated cabinet, is different The access of the biological eyeball of kind is provided convenience;Memory plane is equipped with multiple hemispherical grooves, is placed in each hemispherical groove One heterogeneity biological eyeball, will not cause the mutual pollution between eyeball, indeformable without extruding between adjacent eyeball, to eyeball Quality it is not damaged, the cut quality for the cornea not influenced.
Description of the drawings
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution of the prior art Embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, in describing below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor It puts, can also be obtained according to these attached drawings other attached drawings.
Fig. 1 is schematic structural view of the invention.
Fig. 2 is partition plate structure schematic diagram of the present invention.
Fig. 3 is present invention storage plate structure schematic diagram.
Wherein, refrigerated cabinet 1, memory plane 2, isolation board 3, icehouse 4, card slot 11, case lid 12, fixing buckle 13, carrying buckle 14, Hemispherical groove 21, lifting ring 22, fixed groove track 31, hole 32.
Specific embodiment
Technical scheme is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation Example is part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill Personnel's all other embodiments obtained without making creative work, belong to the scope of protection of the invention.
Keratonosus is the second diseases causing blindness in global range, and corneal transplantation is the current treatment the only effective side of corneal blindness Method.Annual China waits the patient of corneal transplantation probably to have more than 30 ten thousand, and positive the becoming of rising year by year of presenting of this number Gesture.Corneal transplantation is the optimal selection of clinical treatment keratonosus, but China's donor's cornea lacks, according to statistics, annual China The corneal graft only 7,000 or so that major ophthalmologic hospital is completed.The wretched insufficiency of cornea of the same race promotes people continuous The new material that can substitute cornea of the same race is found in research, makes a general survey of the research history of artificial cornea, the glass no matter occurred earliest Cornea or the macromolecule cornea for being applied to clinic now, suffer from such as simple in structure, poor biocompatibility, degradable etc. Shortcoming.Substantial amounts of research is concentrated mainly in cell hetero stroma of cornea material and engineered corneal material this two class. But generally speaking, up to the present except go cell hetero stroma of cornea material this one kind made a breakthrough, and certain applications in It is other engineered all also in the theoretic discussion stage outside clinical test.At present, cell hetero stroma of cornea material is gone to produce Clinical research is only used as, generally laboratory is taken to produce on a small quantity.Since the research and development for removing cell hetero stroma of cornea material will obtain To important breakthrough, once clinical test is completed, it is our asking of must solving that mass production how is carried out to xenogenesis porcine cornea Topic.To the storage of heterogeneity biological eyeball there is no more stringent mode, heterogeneity biological cornea before cutting after eyeball it is equal It is to deposit in unified vial, easily causes pollution, the quality for the cornea that mutual crimp influence is finally cut.
The present invention is described in further detail below by specific embodiment and with reference to attached drawing.
Heterogeneity biological eyeball cold storage plant referring to the drawings 1,2,3, is used to place heterogeneity biological including refrigerated cabinet 1, polylith The memory plane 2 of eyeball;The memory plane 2 is located in the refrigerated cabinet 1, with the refrigerated cabinet 1 removably company of slip It connects;The memory plane 2 is equipped with the hemispherical groove 21 of multiple storage heterogeneity biological eyeballs.It is put in each hemispherical groove 21 A heterogeneity biological eyeball is put, will not cause the mutual pollution between eyeball, it is indeformable without extruding between adjacent eyeball, to eye The quality of ball is not damaged, the cut quality for the cornea not influenced.And the memory plane 2 is slidably in the refrigerated cabinet 1 Therefore middle slip, is provided convenience for the access of heterogeneity biological eyeball;Memory plane 2 is removably fixed on refrigerated cabinet 1 It is interior, convenient for the memory plane 2 is removed cleaning and to the cleaning inside refrigerated cabinet 1.
Further, two isolation boards 3 are further included, the both sides of upper surface and the both sides pair of lower surface in the refrigerated cabinet 1 The card slot 11 of the fixed isolation board 3 should be equipped with;One isolation board 3 is fixed on the card slot 11 of homonymy, and described cold The madial wall for hiding babinet 1 forms the icehouse 4 of storage ice bag.The isolation board 3 can take apart from above-mentioned refrigerated cabinet 1, just In cleaning;The icehouse 4 of formation is convenient for the independent storage of ice bag, keeps apart with biological eyeball, avoids cross-infection.
Further, the isolation board 3 is equipped with and the matched fixed groove track 31 of the memory plane 2, the memory plane 2 Both ends be inserted into the fixed groove track 31, be fixed on isolation board 3.That realizes the memory plane 2 and the refrigerated cabinet 1 can Slide the installation of detachable.
Further, the isolation board 3 is equipped with regularly arranged hole 32.Convenient for air stream whole in refrigerated cabinet 4 It is logical, ensure the refrigerated storage temperature of the biological eyeball of storage.
Further, the refrigerated cabinet 1 sets Packed case lid 12 and fixing buckle 13, and the case lid 12 is closed in refrigerating box It is fixed when on body 1 with the fixing buckle 31.The refrigerated cabinet 1 is sealed, prevents the air in refrigerated cabinet 1 from circulating with extraneous, It pollutes.
Further, the length of the refrigerated cabinet 1 is 45cm, width 44cm, is highly 39cm;The length of the icehouse It spends for 45cm, width 5cm, be highly 39cm.
Further, fixed 31 track of groove track on an isolation board 3 is equipped with 7.It is deposited convenient for holding multiple pieces Plate 2 is stored up, stores multiple heterogeneity biological eyeballs.
Further, the top of the refrigerated cabinet 1 is equipped with carrying buckle 14.Moving and removing convenient for the refrigerated cabinet 1 Fortune.
Further, the number of the hemispherical groove 21 on every piece of memory plane 2 is 10*8.Increase refrigerated cabinet 1 Utilization rate.
Further, the length of the isolation board 3 is 38cm, width 35cm;The width of the fixed groove track 31 is The distance between 0.3cm, adjacent fixed groove track 31 is 4.5cm.
Further, the length of the memory plane 2 be 36cm, width 29cm;Between the adjacent hemispherical groove 21 Spacing be 1cm, the depth of the hemispherical groove is 2cm, and diameter is 2.5cm.
Further, the end of the memory plane 2 is equipped with lifting ring 22, convenient for the extraction or propulsion of memory plane 2.
When accessing eyeball, case lid 12 is opened, directly extracts or promote the memory plane 2 out, before use, carrying out damp and hot go out Bacterium, the immersion that 12h is then carried out in 65 DEG C of 3% hydrogen peroxide go to be heat-treated, place into injection physiological saline and soaked Bubble;The cold storage plant from injection physiological saline is taken out during use, a small amount of added with antibiotic is injected in hemispherical groove Injection physiological saline, prevent from polluting.
Finally it should be noted that:Above example is only to illustrate the technical solution of the invention, rather than its limitations; Although the invention is described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: It still can modify to the technical solution recorded in foregoing embodiments or which part technical characteristic is carried out etc. With replacement;And these modifications or replacement, the essence of appropriate technical solution is not made to depart from each embodiment technology of the invention The spirit and scope of scheme.

Claims (7)

1. heterogeneity biological eyeball cold storage plant, it is characterized in that:
It is used to place the memory plane of heterogeneity biological eyeball including refrigerated cabinet, polylith;
The refrigerated cabinet sets Packed case lid and fixing buckle;The case lid conjunction is consolidated when on refrigerated cabinet with the fixing buckle It is fixed, seal the refrigerated cabinet;The top of the refrigerated cabinet is equipped with carrying buckle;
The memory plane is located in the refrigerated cabinet, is removably slidably connected with the refrigerated cabinet;
The memory plane is equipped with the hemispherical groove of multiple storage heterogeneity biological eyeballs;
Heterogeneity biological eyeball cold storage plant further includes two pieces of isolation boards;The both sides of upper surface and lower surface in the refrigerated cabinet Both sides are correspondingly provided with the card slot of the fixed isolation board;One isolation board is fixed on the card slot of homonymy, and described cold The madial wall for hiding babinet forms the icehouse of storage ice bag;
The isolation board is equipped with and the matched fixed groove track of the memory plane;The fixation is inserted at the both ends of the memory plane Groove track is fixed on isolation board.
2. heterogeneity biological eyeball cold storage plant according to claim 1, it is characterized in that:
The number of hemispherical groove on every piece of memory plane is 10*8.
3. heterogeneity biological eyeball cold storage plant according to claim 1, it is characterized in that:
The length of the memory plane is 36cm, width 29cm;Spacing between the adjacent hemispherical groove 21 is 1cm, institute The depth for stating hemispherical groove is 2cm, and diameter is 2.5cm.
4. heterogeneity biological eyeball cold storage plant according to claim 1, it is characterized in that:
The isolation board is equipped with regularly arranged hole;
The length of the isolation board is 38cm, width 35cm;
The width of the fixed groove track is 0.3cm, and the distance between adjacent fixed groove track is 4.5cm.
5. heterogeneity biological eyeball cold storage plant according to claim 1, it is characterized in that:
The length of the refrigerated cabinet is 40cm~50cm, width is 36cm~45cm, is highly 35cm~40cm;The icehouse Length be 40cm~50cm, width is 3cm~8cm, is highly 35cm~40cm.
6. heterogeneity biological eyeball cold storage plant according to claim 1, it is characterized in that:
The length of the refrigerated cabinet is 45cm, width 44cm, is highly 39cm;The length of the icehouse is 45cm, width For 5cm, be highly 39cm.
7. heterogeneity biological eyeball cold storage plant according to claim 1, it is characterized in that:
The fixed groove track on one isolation board is equipped with 7.
CN201610030578.0A 2016-01-18 2016-01-18 Heterogeneity biological eyeball cold storage plant Active CN105466097B (en)

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CN105466097B true CN105466097B (en) 2018-05-22

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110638585A (en) * 2019-08-18 2020-01-03 莱芜职业技术学院 Isolating device for preventing infection for clinical medicine

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201277775Y (en) * 2008-09-28 2009-07-22 孟绍东 Board separation type cold storage box
CN201634086U (en) * 2010-04-14 2010-11-17 北京物资学院 Portable insulation can with detachable cold accumulation container
JP2012131546A (en) * 2010-12-22 2012-07-12 Globeride Inc Cold box, and inner lid for the same
CN102673894A (en) * 2012-05-15 2012-09-19 苏州国环环境检测有限公司 Portable refrigeration sample box
CN202807251U (en) * 2012-09-26 2013-03-20 天津瀛德科技有限公司 Cold-chain logistic transportation cold keeping box
CN204078452U (en) * 2014-09-23 2015-01-07 浙江太古制冷科技有限公司 A kind of cold chain transportation case
CN104495073A (en) * 2014-11-24 2015-04-08 中科美菱低温科技有限责任公司 Medical cryogenic box
CN204606599U (en) * 2015-04-27 2015-09-02 河南中科干细胞基因工程有限公司 Stem cell carrying case
CN204822613U (en) * 2015-08-06 2015-12-02 山东商业职业技术学院 Be used for biological experiment sample dry ice transport case
CN205403287U (en) * 2016-01-18 2016-07-27 广州中大南沙科技创新产业园有限公司 Novel biological eyeball of xenogenesis is cold -stored device

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201277775Y (en) * 2008-09-28 2009-07-22 孟绍东 Board separation type cold storage box
CN201634086U (en) * 2010-04-14 2010-11-17 北京物资学院 Portable insulation can with detachable cold accumulation container
JP2012131546A (en) * 2010-12-22 2012-07-12 Globeride Inc Cold box, and inner lid for the same
CN102673894A (en) * 2012-05-15 2012-09-19 苏州国环环境检测有限公司 Portable refrigeration sample box
CN202807251U (en) * 2012-09-26 2013-03-20 天津瀛德科技有限公司 Cold-chain logistic transportation cold keeping box
CN204078452U (en) * 2014-09-23 2015-01-07 浙江太古制冷科技有限公司 A kind of cold chain transportation case
CN104495073A (en) * 2014-11-24 2015-04-08 中科美菱低温科技有限责任公司 Medical cryogenic box
CN204606599U (en) * 2015-04-27 2015-09-02 河南中科干细胞基因工程有限公司 Stem cell carrying case
CN204822613U (en) * 2015-08-06 2015-12-02 山东商业职业技术学院 Be used for biological experiment sample dry ice transport case
CN205403287U (en) * 2016-01-18 2016-07-27 广州中大南沙科技创新产业园有限公司 Novel biological eyeball of xenogenesis is cold -stored device

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