CN105456328A - Nursing gel containing periplaneta americana and preparation method thereof - Google Patents
Nursing gel containing periplaneta americana and preparation method thereof Download PDFInfo
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- CN105456328A CN105456328A CN201510993280.5A CN201510993280A CN105456328A CN 105456328 A CN105456328 A CN 105456328A CN 201510993280 A CN201510993280 A CN 201510993280A CN 105456328 A CN105456328 A CN 105456328A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses nursing gel containing periplaneta americana. The nursing gel is prepared from periplaneta americana extract and honeysuckle flower extract. The nursing gel has the advantages of safe and reliable use and remarkable curative effect.
Description
Technical field
The invention belongs to cosmetics of everyday use processing technique field, be specifically related to a kind of nursing gel containing periplaneta americana and preparation method thereof.
Background technology
Cervicitis is a kind of inflammation, has the feature of general inflammation equally: coup injury causes acute inflammation, and long-term pathogenic infection or body resistivity decline and acute inflammation does not cure delay for chronic etc., and all chronic inflammatory diseases all may canceration.
Cervicitis causes female acyesis and cervical cancer, is one of the most frightened disease of gynecological.Its easy paathogenic factor is as follows: 1, gynecilogical operation.Childbirth, induced labor, miscarriage etc. cause after cervix uteri sustains damage, and pathogenic bacteria invades, and easily causes cervical erosion.In addition, antibacterial often can enter into uterus, fallopian tube etc. by cervical canal is up, causes infection.Simultaneously because urethra, anus are all opened near vaginal orifice, easily pollute vaginal orifice during defecation, cause infection.2, sexual life.Sexual life also by various different microorganism, can comprise gonococcus, chlamydia trachomatis etc. and takes intravaginal to, cause infection.In addition, seminal fluid is attached to and vagina can makes the basicity of vagina raise, thus makes intravaginal environment meta-alkalescence, and pathogenic flora increases, and easily suffers from cervicitis.3, natural artificial abortion, diagnostic curettage and childbirth cause cervicitis: although spontaneous abortion and childbirth might not be performed an operation, but to cervix uteri and respectively organize the damage caused in various degree, very easily cause cervicitis.And for the women had a manual miscarriage, dilatation and curettage of uterine is performed the operation, the sickness rate of cervicitis is higher, mechanical irritation or the damage of this type of operation are apparent, and are easy to infect, and cause cervicitis and other gynecological inflammations.4, or alkaline solution washing vagina acid with certain, or suppository is put into vagina, all can cause cervicitis.
There is the women of cervicitis, cervical cancer incidence rate is apparently higher than general population, under the stimulation of long-term chronic inflammation, cervical canal hypertrophy and come columnar epithelium can there is atypical hyperplasia, if can not get treatment correct in time, will gradually to precancerous lesions of uterine cervix future development, the symptoms such as the leucorrhoea grow in quantity caused by cervicitis, lumbago, lower abdomen falling inflation can affect the emotion of people, and from anti-cancer angle, cervicitis and Cervical Cancer close.Cervicitis disease delays treatment, can cause larger harm, certainly also can cause female acyesis.Clinically, although there is the multiple lotion for the treatment of cervicitis, suppository, Chinese medicine and western medicine, various naturopathy etc. for oral administration, say and both facilitate, economical, effective, and without any side effects again, also do not having so desirable medicine and method at present.
Summary of the invention
The object of this invention is to provide a kind of nursing gel containing periplaneta americana, this nursing gel effectively can cure cervicitis.
The technical solution used in the present invention is a kind of nursing gel containing periplaneta americana, and this nursing gel comprises American-cockroach-extract, Flos Lonicerae extract.
As preferably, this nursing gel also comprises solvent, emollient, pH adjusting agent and antiseptic.
As preferably, described solvent is selected from water or butanediol, or their arbitrary proportion mixture; Described emollient is selected from the one in glycerol, betanin or carbomer, or their arbitrary proportion mixture; Described pH adjusting agent is selected from triethanolamine; Described antiseptic is selected from ethylhexyl glycerol or Methylisothiazolinone, or their arbitrary proportion mixture.
As preferably, this nursing gel is made up of the component of following parts by weight: 60 ~ 100 parts, water, butanediol 1 ~ 5 part, glycerol 1 ~ 10 part, betanin 1 ~ 10 part, American-cockroach-extract 1 ~ 10 part, Flos Lonicerae extract 1 ~ 10 part, carbomer 0.5 ~ 5 part, triethanolamine 0.5 ~ 5 part, ethylhexyl glycerol 0.01 ~ 1 part and Methylisothiazolinone 0.01 ~ 1 part.
As preferably, this nursing gel is made up of the component of following parts by weight: 80 parts, water, butanediol 2 parts, glycerol 5 parts, betanin 3 parts, American-cockroach-extract 4 parts, Flos Lonicerae extract 4 parts, carbomer 1.5 parts, triethanolamine 1.5 parts, ethylhexyl glycerol 0.1 part and Methylisothiazolinone 0.1 part.
As preferably, the preparation method of described American-cockroach-extract, comprises the following steps: get periplaneta americana, adds soak with ethanol, then reflux, extract, filters, obtains alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains American-cockroach-extract.
As preferably, described Radix Ophiopogonis extract preparation method, comprise the following steps: get Radix Ophiopogonis, add soak with ethanol, then reflux, extract, filter, obtain alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains Radix Ophiopogonis extract.
The present invention also provides a kind of method preparing described nursing gel, comprises the following steps: by proportioning, takes American-cockroach-extract and Flos Lonicerae extract, and mixing, adds appropriate amount of auxiliary materials, make gel.
Periplaneta americana is a kind of insecticide, to have survived 3.5 hundred million years be on earth the most ancient, procreation the most successful insect assembly so far in the world.Shennong's Herbal, Compendium of Material Medica are all included record to modern " national Chinese herbal medicine compilation " and " Chinese medicine voluminous dictionary ", are classified as important Chinese medicine.There is antitumor, improve immunity, protect the liver, promote the effects such as tissue repair, anti-inflammatory and antalgic, slow down aging.Compatibility Flos Lonicerae extract makes gel again, for cervicitis women uterus neck, within one to two day, change dressings once, a week is a course for the treatment of, except have the uterus of canceration or have idiocratic patient be difficult to recover except, other cervicitis vaginitiss, Be very effective, general recovery from illness one to three courses for the treatment of, consider and improve further curative effect and easy to use, be convenient to popularization and thousands upon thousands women can be can use.
Beneficial effect of the present invention is: the nursing gel that the present invention adopts American-cockroach-extract, Flos Lonicerae extract is made, and can effectively administer the gynecological inflammation such as cervicitis, vaginitis, safe and reliable.
Detailed description of the invention
For making those skilled in the art understand production technology of the present invention and technique effect in detail, introduce application of the present invention and technique effect further with concrete production instance below.
Embodiment 1
By weight, take 80 parts, water, butanediol 2 parts, glycerol 5 parts, betanin 3 parts, American-cockroach-extract 4 parts, Flos Lonicerae extract 4 parts, carbomer 1.5 parts, triethanolamine 1.5 parts, ethylhexyl glycerol 0.1 part and Methylisothiazolinone 0.1 part, mixing, makes the gel of 5 grams every.Using method: use before sleeping evening, each one, uses primary effect better for every other day or two days.Use front clean hands, open gel safety guard, ring catch bar filled in pipe, get dorsal position, buttocks is raised slightly, pipe is inserted gently then gel pushed away in affected part close to cervix uteri, preferably lie on the back 30 to 60 minutes.
Wherein, the preparation method of American-cockroach-extract, comprises the following steps: get periplaneta americana, adds soak with ethanol 48 ~ 60 hours, then reflux, extract, filters, obtains alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains American-cockroach-extract.
Described Radix Ophiopogonis extract preparation method, comprise the following steps: get Radix Ophiopogonis, add soak with ethanol 48 ~ 60 hours, then reflux, extract, filter, obtain alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains Radix Ophiopogonis extract.
Embodiment 2
By weight, take 60 parts, water, butanediol 1 part, glycerol 1 part, betanin 1 part, American-cockroach-extract 1 part, Flos Lonicerae extract 1 part, carbomer 0.5 part, triethanolamine 0.5 part, ethylhexyl glycerol 0.01 part and Methylisothiazolinone 0.01 part, mixing, makes the gel of 5 grams every.Using method: use before sleeping evening, each one, uses primary effect better for every other day or two days.Use front clean hands, open gel safety guard, ring catch bar filled in pipe, get dorsal position, buttocks is raised slightly, pipe is inserted gently then gel pushed away in affected part close to cervix uteri, preferably lie on the back 30 to 60 minutes.
Wherein, the preparation method of American-cockroach-extract, comprises the following steps: get periplaneta americana, adds soak with ethanol 48 ~ 60 hours, then reflux, extract, filters, obtains alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains American-cockroach-extract.
Described Radix Ophiopogonis extract preparation method, comprise the following steps: get Radix Ophiopogonis, add soak with ethanol 48 ~ 60 hours, then reflux, extract, filter, obtain alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains Radix Ophiopogonis extract.
Embodiment 3
By weight, take 100 parts, water, butanediol 5 parts, glycerol 10 parts, betanin 10 parts, American-cockroach-extract 10 parts, Flos Lonicerae extract 10 parts, carbomer 5 parts, triethanolamine 5 parts, ethylhexyl glycerol 1 part and Methylisothiazolinone 1 part, mixing, makes the gel of 5 grams every.Using method: use before sleeping evening, each one, uses primary effect better for every other day or two days.Use front clean hands, open gel safety guard, ring catch bar filled in pipe, get dorsal position, buttocks is raised slightly, pipe is inserted gently then gel pushed away in affected part close to cervix uteri, preferably lie on the back 30 to 60 minutes.
Wherein, the preparation method of American-cockroach-extract, comprises the following steps: get periplaneta americana, adds soak with ethanol 48 ~ 60 hours, then reflux, extract, filters, obtains alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains American-cockroach-extract.
Described Radix Ophiopogonis extract preparation method, comprise the following steps: get Radix Ophiopogonis, add soak with ethanol 48 ~ 60 hours, then reflux, extract, filter, obtain alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains Radix Ophiopogonis extract.
For verifying technique effect of the present invention, the following test of special do:
Criterion of therapeutical effect (happy outstanding, " obstetrics and gynecology ", People's Health Publisher, 2006:264)
Cure: clinical symptoms and sign disappear, vaginal secretions, cervix uteri mouth of pipe secretions microscopy and cultivation are negative.
Effective: clinical symptoms and sign obviously alleviate, vaginal secretions, cervix uteri mouth of pipe secretions microscopy and cultivation are negative.
Effective: clinical symptoms and sign alleviate, vaginal secretions, cervix uteri mouth of pipe secretions microscopy and cultivation are positive.
Invalid: symptom and sign are unchanged compared with before treatment.
Suffer from the Clinical practice of cervicitis women through more than 5,000, the patient of 70% cures, and the patient of 91% is effective, achieves significant progress.Except various cervicitis, to vaginitis, various wound, scald, burn, also all there is good effect.
Finally it should be noted that, above embodiment is the unrestricted technical scheme of the present invention in order to explanation only, although with reference to above-described embodiment to invention has been detailed description, those skilled in the art are to be understood that, still can modify to the present invention or equivalent replacement, and not departing from any modification or partial replacement of the spirit and scope of the present invention, it all should be encompassed in right of the present invention.
Claims (8)
1. the nursing gel containing periplaneta americana, it is characterized in that, this nursing gel comprises American-cockroach-extract, Flos Lonicerae extract.
2. a kind of nursing gel containing periplaneta americana according to claim 1, it is characterized in that, this nursing gel also comprises solvent, emollient, pH adjusting agent and antiseptic.
3. a kind of nursing gel containing periplaneta americana according to claim 2, it is characterized in that, described solvent is selected from water or butanediol, or their arbitrary proportion mixture; Described emollient is selected from the one in glycerol, betanin or carbomer, or their arbitrary proportion mixture; Described pH adjusting agent is selected from triethanolamine; Described antiseptic is selected from ethylhexyl glycerol or Methylisothiazolinone, or their arbitrary proportion mixture.
4. a kind of nursing gel containing periplaneta americana according to claim 3, it is characterized in that, this nursing gel is made up of the component of following parts by weight: 60 ~ 100 parts, water, butanediol 1 ~ 5 part, glycerol 1 ~ 10 part, betanin 1 ~ 10 part, American-cockroach-extract 1 ~ 10 part, Flos Lonicerae extract 1 ~ 10 part, carbomer 0.5 ~ 5 part, triethanolamine 0.5 ~ 5 part, ethylhexyl glycerol 0.01 ~ 1 part and Methylisothiazolinone 0.01 ~ 1 part.
5. a kind of nursing gel containing periplaneta americana according to claim 4, it is characterized in that, this nursing gel is made up of the component of following parts by weight: 80 parts, water, butanediol 2 parts, glycerol 5 parts, betanin 3 parts, American-cockroach-extract 4 parts, Flos Lonicerae extract 4 parts, carbomer 1.5 parts, triethanolamine 1.5 parts, ethylhexyl glycerol 0.1 part and Methylisothiazolinone 0.1 part.
6. a kind of nursing gel containing periplaneta americana according to claim 1, it is characterized in that, the preparation method of described American-cockroach-extract, comprises the following steps: get periplaneta americana, adds soak with ethanol, then reflux, extract, filters, obtains alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains American-cockroach-extract.
7. a kind of nursing gel containing periplaneta americana according to claim 1, is characterized in that, described Radix Ophiopogonis extract preparation method, comprise the following steps: get Radix Ophiopogonis, add soak with ethanol, then reflux, extract, filter, obtain alcohol extract and slag; Described slag adds soak by water again, obtains aqueous extract; Respectively by described alcohol extract and aqueous extract simmer down to extractum, mixing, obtains Radix Ophiopogonis extract.
8. prepare a method for nursing gel described in claim 1-7 any one, it is characterized in that, comprise the following steps: by proportioning, take American-cockroach-extract and Flos Lonicerae extract, mixing, adds appropriate amount of auxiliary materials, makes gel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510993280.5A CN105456328A (en) | 2015-12-28 | 2015-12-28 | Nursing gel containing periplaneta americana and preparation method thereof |
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| CN201510993280.5A CN105456328A (en) | 2015-12-28 | 2015-12-28 | Nursing gel containing periplaneta americana and preparation method thereof |
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| CN105456328A true CN105456328A (en) | 2016-04-06 |
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| CN201510993280.5A Pending CN105456328A (en) | 2015-12-28 | 2015-12-28 | Nursing gel containing periplaneta americana and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108403723A (en) * | 2018-05-07 | 2018-08-17 | 中国科学院昆明动物研究所 | A kind of American-cockroach-extract that intervening AD and its extracting method and application |
-
2015
- 2015-12-28 CN CN201510993280.5A patent/CN105456328A/en active Pending
Non-Patent Citations (3)
| Title |
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| 孙显军等: "《土单方》", 31 December 2014, 江西科学技术出版社 * |
| 李淑芝等: "康复新液的临床观察", 《华西药学杂志》 * |
| 罗诚等: "康复新凝胶剂的制备与质量控制", 《时珍国医国药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108403723A (en) * | 2018-05-07 | 2018-08-17 | 中国科学院昆明动物研究所 | A kind of American-cockroach-extract that intervening AD and its extracting method and application |
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