CN105456039A - Visible light cured dental restorative composition and preparation method thereof - Google Patents
Visible light cured dental restorative composition and preparation method thereof Download PDFInfo
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- CN105456039A CN105456039A CN201510941083.9A CN201510941083A CN105456039A CN 105456039 A CN105456039 A CN 105456039A CN 201510941083 A CN201510941083 A CN 201510941083A CN 105456039 A CN105456039 A CN 105456039A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
- A61K6/887—Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/71—Fillers
- A61K6/76—Fillers comprising silicon-containing compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/71—Fillers
- A61K6/77—Glass
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- Oral & Maxillofacial Surgery (AREA)
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Abstract
The invention provides a visible light cured dental restorative composition and a preparation method thereof. The composition comprises components in the following parts by weight: 30-55 parts of an oligomer resin, 20-40 parts of an active diluent, 10-20 parts of an inorganic filler, 3-7 parts of a photoinitiator, and 3-7 parts of a co-initiator. Compared with the prior art, the application has the advantages that curing with visible light is suitable for long-term operation, direct operation is available in the mouth of a patient, using is facilitated, and clinical operation is facilitated; a traditional bi-component chemically cured composite resin is abandoned, a single-component photo-curing system is introduced, post-curing heat production is low, and volume contraction is low; the use of visible light curing initiator avoids ultraviolet injuring the patient and doctors; by introducing the inorganic filler and using a wet bonding technique and an organic substrate to form a composite, and the cured material has good mechanical properties, such as wear resistance and hardness.
Description
Technical field
The present invention relates to a kind of visible-light curing dental restorative compositions and preparation method thereof.
Background technology
The treatment of dentistry is different from the treatment of general diseases, and except using except medicine, be much the cavity of defect in order to repair tooth and filling tooth, therefore the repair materials of dental is very important medical material.
The kind of dental prosthetic material is a lot, and for repairing because of dental caries, the reasons such as wound cause the repair materials of dental defect to mainly contain three classes: alloy material, examine porcelain and composite resin.Silver tribute alloy is as existing more than the 160 year history of dental filling material, existing still as the common used material of backteeth filling.But silver-colored tribute alloy and creamy white matching poor, easily there is electrochemical corrosion and creep, particularly in production with to use in link hydrargyrum to cause severe contamination and dangerous to human body to environment, many developed countries limited and forbids silver-colored tribute alloy to carry out Dental Erosion.The sixties in 20th century, composite resin is as a kind of aesthetic restorative materials, because it is easy and simple to handle, color and luster selects motility large, the features such as physicochemical property is superior, meet the requirement that clinician and patient repair dental prosthetics greatly, and the deficiency of resin material in hardness and wearability before compensate for, firmly chemical bond can be produced again with enamel and dentin, decrease the cutting of tooth body, save natural dental hard tissue to greatest extent, now become restoration of tooth and treated requisite important materials.
Traditional chemical curing type composite resin is bi-component, and because in solidification, heat production is higher, after solidification, volume contraction is larger, after bi-component mixing, the operating time is short, directly should not repair in patient's mouth, need indirectly to make, make troubles to clinical, thus gradually replace by light-cured type composite resin.
In addition, light-cured type composite resin can also be used as anticariogenic pit and fissure sealant, the adhesive that dummy and tooth body are shown in, the core stake resin material etc. of false teeth base tray material and sub-hat shape reconstruction.Due to skin, mucosa and eyes can be caused carcinogenic, the danger such as photo sensitive reaction and tissue bums by irradiation under ultraviolet ray for a long time, in order to avoid ultraviolet light to the injury of patient's oral cavity tissue and reduce ultraviolet light to the damage of doctor's eyes, patent of the present invention adopts visible light initiator, introduce a kind of visible light curable dental prosthetic material, thus avoid several large shortcoming of ultraviolet initiator.
Summary of the invention
For defect of the prior art, the object of this invention is to provide a kind of visible-light curing dental restorative compositions and preparation method thereof.The composite resin of the dental prosthetic in patent of the present invention is a kind of material combined by organic resin matrix and surface treated inorganic filler and initiator system.The features such as the light-cured type composite resin of patent of the present invention is one-component, has solidification rate fast, easy to use, and the rear resin property of solidification is excellent.Patent of the present invention adds novel inorganic filler in addition, in conjunction with the development of moist bonding technology, the physical and mechanical property of dental prosthetic light-cured composite is greatly improved, exceed traditional amalgam restorations material in some aspects, progressively substituted silver amalgam material and be used for front and back tooth.
The object of the invention is to be achieved through the following technical solutions:
The invention provides a kind of visible-light curing dental restorative compositions, described compositions comprises each component of following weight portion:
About composite formula in fact have a lot of in implementation method, be not limited to above scope, the good operability of oligomer resin to be 30-55 part or reactive diluent the be viscosity considering product, can affect the anti-wear performance of tooth too much.
Preferably, described oligomer resin is selected from one or more in bisphenol-A glycidyl methacrylate (bis-GMA), bisphenol-A ethoxyquin dimethylacrylate (bis-EMA), carbamic acid double methyl methacrylate (UDMA), modified bisphenol A glycidyl methacrylate (modification bis-GMA); Wherein, described, modified bisphenol A glycidyl methacrylate (modification bis-GMA) specifically refers to bis-GMA antibiotic property or viscosity modified modification.
Preferably, described reactive diluent is selected from one or more in ethylene glycol dimethacrylate, TEGDMA (TEGDMA), diethylene glycol diacrylate (EGDMA).
Preferably, described inorganic filler to be selected from one in surface treated strontium glass powder, aerosil, ceramic end or several; Described surface treatment specifically instigates it more can by the process of oligomer and diluent wetting and dispersing.
Preferably, described light trigger be selected from camphorquinone (CQ), fluoro diphenyl titanium luxuriant in one or both.
Preferably, described aided initiating is selected from tertiary amine-type reactive diluent, specifically the acrylate of a class band tertiary amine group, commercially available example comprise Sartomer CN371, Changxing 7100,6422, dimethylaminoethyl methacrylate (DMAEM).
Second aspect, the invention provides a kind of preparation method of described visible-light curing dental restorative compositions, described preparation method comprises the steps:
Step one, described oligomer resin to be dissolved in the described reactive diluent of part, to stir to abundant dissolving, obtain mixture A; Described inorganic filler is mixed with the described reactive diluent of residue, is stirred to abundant dispersion, obtains mixture B;
Step 2, described mixture A to be mixed homogeneously with described mixture B, obtain mixture C;
Step 3, to light trigger, aided initiating described in described mixture C, mix homogeneously, cooling, side viscosity solid content, filter and obtain described visible-light curing dental restorative compositions.
Preferably, in step one, described oligomer resin needs to carry out baking the affected part after applying some drugs before use; The condition of described baking the affected part after applying some drugs is 60-70 DEG C, 1h;
Preferably, in step 3, the mode of described mix homogeneously is high-speed stirred under 1000rpm-2000rpm;
Preferably, in step 3, the mode of described cooling is natural cooling.
Preferably, in step 3, during described viscosity solid content > 98%, obtain target product.
Compared with prior art, the present invention has following beneficial effect:
(1) long with visible-light curing operable time, should in patient's mouth straightforward manipulation, easy to use, be convenient to clinical manipulation;
(2) patent of the present invention abandons traditional double component chemosetting type composite resin, introduces single-component photocureable system, and after solidification, heat production is low, and volume contraction is little;
(3) patent of the present invention adopts visible-light curing initiator, avoids ultraviolet to cause damage to patient and doctor;
(4) patent of the present invention introduces novel inorganic filler, adopts moist bonding technology, and organic substrate composition composite, has good mechanical performance: wearability and hardness etc. after solidification.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail.Following examples will contribute to those skilled in the art and understand the present invention further, but not limit the present invention in any form.It should be pointed out that to those skilled in the art, without departing from the inventive concept of the premise, some distortion and improvement can also be made.These all belong to protection scope of the present invention.
Sharpest edges of the present invention are exactly can cause with visible ray and cause the sequence of operations that brings and the reduction to greatest extent to human injury due to visible ray, compared with existing technology, other performance outside decapacitation visible-light curing is large especially advantage not, so the present invention cannot provide performance and the index of concrete compositions, not adopting the dental prosthetic material of inorganic filler almost not have, contrasting with not adopting the compositions of this inorganic filler so do not exist yet.
embodiment 1
The present embodiment provides a kind of visible-light curing dental restorative compositions and preparation thereof, and component and the parts by weight of described compositions are as shown in table 1 below:
Table 1
Described visible-light curing dental restorative compositions is prepared by the following method:
(1) be dissolved in the reactive diluent accounting for total system 20% after drying 1h by oligomer resin 60-70 DEG C that accounts for the total system of coating 30%, stir to abundant dissolving;
(2) by accounting for the inorganic filler of the total system of coating 20% and accounting for the reactive diluent of the total system 20% of coating, abundant dispersion is stirred to;
(3) step (2) gained mixture and step (1) gained mixture are uniformly mixed;
(4) initiator accounting for coating system 10% being added step (3) gained mixture obtains in mixture, high-speed stirred mix homogeneously; Cooling, viscosimetric solids content, filters and packages and obtains visible-light curing dental restorative compositions.
embodiment 2
The present embodiment provides a kind of visible-light curing dental restorative compositions and preparation thereof, and component and the parts by weight of described compositions are as shown in table 2 below:
Table 2
Described visible-light curing dental restorative compositions is prepared by the following method:
(1) be dissolved in the reactive diluent accounting for total system 20% after drying 1h by oligomer resin 60-70 DEG C that accounts for the total system of coating 40%, stir to abundant dissolving;
(2) by accounting for the inorganic filler of the total system of coating 15% and accounting for the reactive diluent of the total system 15% of coating, abundant dispersion is stirred to;
(3) step (2) gained mixture and step (1) gained mixture are uniformly mixed;
(4) initiator accounting for coating system 10% being added step (3) gained mixture obtains in mixture, high-speed stirred mix homogeneously; Cooling, viscosimetric solids content, filters and packages and obtains visible-light curing dental restorative compositions.
embodiment 3
The present embodiment provides a kind of visible-light curing dental restorative compositions and preparation thereof, and component and the parts by weight of described compositions are as shown in table 3 below:
Table 3
Described visible-light curing dental restorative compositions is prepared by the following method:
(1) be dissolved in the reactive diluent accounting for total system 15% after drying 1h by oligomer resin 60-70 DEG C that accounts for the total system of coating 55%, stir to abundant dissolving;
(2) by accounting for the inorganic filler of the total system of coating 10 ~ 30% and accounting for the reactive diluent of the total system 10% of coating, abundant dispersion is stirred to;
(3) step (2) gained mixture and step (1) gained mixture are uniformly mixed;
(4) initiator accounting for coating system 10% being added step (3) gained mixture obtains in mixture, high-speed stirred mix homogeneously; Cooling, viscosimetric solids content, filters and packages and obtains visible-light curing dental restorative compositions.
performance test
Table 4
Conclusion: when some key propertys and universal compositions of ultraviolet curing type keep same level substantially again, the present embodiment achieves the solidification of visible ray.
Above specific embodiments of the invention are described.It is to be appreciated that the present invention is not limited to above-mentioned particular implementation, those skilled in the art can make various distortion or amendment within the scope of the claims, and this does not affect flesh and blood of the present invention.
Claims (9)
1. a visible-light curing dental restorative compositions, is characterized in that, described compositions comprises each component of following weight portion:
2. visible-light curing dental restorative compositions according to claim 1, it is characterized in that, described oligomer resin is selected from one or more in bisphenol-A glycidyl methacrylate, bisphenol-A ethoxyquin dimethylacrylate, carbamic acid double methyl methacrylate, modified bisphenol A glycidyl methacrylate.
3. visible-light curing dental restorative compositions according to claim 1, is characterized in that, described reactive diluent is selected from one or more in ethylene glycol dimethacrylate, TEGDMA, diethylene glycol diacrylate.
4. visible-light curing dental restorative compositions according to claim 1, is characterized in that, described inorganic filler to be selected from one in surface treated strontium glass powder, aerosil, ceramic end or several.
5. visible-light curing dental restorative compositions according to claim 1, is characterized in that, described light trigger be selected from camphorquinone, fluoro diphenyl titanium luxuriant in one or both.
6. visible-light curing dental restorative compositions according to claim 1, is characterized in that, described aided initiating is selected from tertiary amine-type reactive diluent.
7. a preparation method for visible-light curing dental restorative compositions described in any one of claim 1-6, is characterized in that, described preparation method comprises the steps:
Step one, described oligomer resin to be dissolved in the described reactive diluent of part, to stir to abundant dissolving, obtain mixture A; Described inorganic filler is mixed with the described reactive diluent of residue, is stirred to abundant dispersion, obtains mixture B;
Step 2, described mixture A to be mixed homogeneously with described mixture B, obtain mixture C;
Step 3, in described mixture C, add described light trigger, aided initiating, mix homogeneously, cooling, side viscosity solid content, filter and obtain described visible-light curing dental restorative compositions.
8. the preparation method of visible-light curing dental restorative compositions according to claim 7, it is characterized in that, in step one, described oligomer resin needs to carry out baking the affected part after applying some drugs before use; The condition of described baking the affected part after applying some drugs is 60-70 DEG C, 1h.
9. the preparation method of visible-light curing dental restorative compositions according to claim 7, it is characterized in that, in step 3, the mode of described mix homogeneously is 1000rpm-2000rpm high-speed stirred; The mode of described cooling is natural cooling.
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| CN201510941083.9A CN105456039A (en) | 2015-12-15 | 2015-12-15 | Visible light cured dental restorative composition and preparation method thereof |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106265104A (en) * | 2016-08-22 | 2017-01-04 | 黄栋杰 | The material of a kind of tooth-whitening and method |
| CN106361581A (en) * | 2016-10-21 | 2017-02-01 | 郑州源冉生物技术有限公司 | Tooth photocuring repairing material and preparing method thereof |
| CN106619143A (en) * | 2016-10-20 | 2017-05-10 | 郑州源冉生物技术有限公司 | Novel material for photo-curing repairing of teeth and preparation method thereof |
| CN107502040A (en) * | 2016-06-14 | 2017-12-22 | 中国科学院化学研究所 | A kind of visible-light curing solvent-free type environment-friendly ink composite |
| CN108403445A (en) * | 2018-06-05 | 2018-08-17 | 苏州新益特塑胶科技有限公司 | A kind of light-cured composite material |
| CN108578249A (en) * | 2018-04-12 | 2018-09-28 | 华南理工大学 | One kind is double containing long oxyalkyl chain（Methyl）Lower shrinkage stress dentistry composite resin of acrylate and preparation method thereof |
| CN109199874A (en) * | 2018-11-07 | 2019-01-15 | 西南交通大学 | A kind of compound resin and preparation method thereof |
| CN109363953A (en) * | 2018-11-27 | 2019-02-22 | 吉林省登泰克牙科材料有限公司 | A kind of dental 3D printing resin liquid composition, preparation method and application |
| CN109498466A (en) * | 2018-11-27 | 2019-03-22 | 吉林省登泰克牙科材料有限公司 | It is a kind of for dentistry porcelain veneer and photocuring general-purpose adhesive composition, preparation method and the application of collapsing porcelain reparation |
| CN110461886A (en) * | 2017-03-29 | 2019-11-15 | 三井化学株式会社 | Photocurable composition, basal seat area and with support artificial tooth |
| JPWO2020174783A1 (en) * | 2019-02-27 | 2021-12-02 | 富士フイルム株式会社 | Inkjet ink composition for polyvinyl chloride building materials, image recording method and image recording |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107502040A (en) * | 2016-06-14 | 2017-12-22 | 中国科学院化学研究所 | A kind of visible-light curing solvent-free type environment-friendly ink composite |
| CN106265104A (en) * | 2016-08-22 | 2017-01-04 | 黄栋杰 | The material of a kind of tooth-whitening and method |
| CN106619143A (en) * | 2016-10-20 | 2017-05-10 | 郑州源冉生物技术有限公司 | Novel material for photo-curing repairing of teeth and preparation method thereof |
| CN106361581A (en) * | 2016-10-21 | 2017-02-01 | 郑州源冉生物技术有限公司 | Tooth photocuring repairing material and preparing method thereof |
| CN110461886B (en) * | 2017-03-29 | 2022-03-22 | 三井化学株式会社 | Photocurable composition, denture base and denture with base |
| CN110461886A (en) * | 2017-03-29 | 2019-11-15 | 三井化学株式会社 | Photocurable composition, basal seat area and with support artificial tooth |
| CN108578249B (en) * | 2018-04-12 | 2019-08-20 | 华南理工大学 | A kind of lower shrinkage stress dentistry composite resin and preparation method thereof of bis- (methyl) acrylate Han long oxyalkyl chain |
| CN108578249A (en) * | 2018-04-12 | 2018-09-28 | 华南理工大学 | One kind is double containing long oxyalkyl chain（Methyl）Lower shrinkage stress dentistry composite resin of acrylate and preparation method thereof |
| CN108403445A (en) * | 2018-06-05 | 2018-08-17 | 苏州新益特塑胶科技有限公司 | A kind of light-cured composite material |
| CN109199874A (en) * | 2018-11-07 | 2019-01-15 | 西南交通大学 | A kind of compound resin and preparation method thereof |
| CN109363953A (en) * | 2018-11-27 | 2019-02-22 | 吉林省登泰克牙科材料有限公司 | A kind of dental 3D printing resin liquid composition, preparation method and application |
| CN109498466A (en) * | 2018-11-27 | 2019-03-22 | 吉林省登泰克牙科材料有限公司 | It is a kind of for dentistry porcelain veneer and photocuring general-purpose adhesive composition, preparation method and the application of collapsing porcelain reparation |
| CN109363953B (en) * | 2018-11-27 | 2022-03-15 | 吉林省登泰克牙科材料有限公司 | Dental 3D printing resin liquid composition, and preparation method and application thereof |
| JPWO2020174783A1 (en) * | 2019-02-27 | 2021-12-02 | 富士フイルム株式会社 | Inkjet ink composition for polyvinyl chloride building materials, image recording method and image recording |
| JP7279148B2 (en) | 2019-02-27 | 2023-05-22 | 富士フイルム株式会社 | Inkjet ink composition for polyvinyl chloride building materials, image recording method and image recorded matter |
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Application publication date: 20160406 |