CN106265104A - The material of a kind of tooth-whitening and method - Google Patents

The material of a kind of tooth-whitening and method Download PDF

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Publication number
CN106265104A
CN106265104A CN201610700717.6A CN201610700717A CN106265104A CN 106265104 A CN106265104 A CN 106265104A CN 201610700717 A CN201610700717 A CN 201610700717A CN 106265104 A CN106265104 A CN 106265104A
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Prior art keywords
tooth
whitening
agent
photocuring
etching
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CN201610700717.6A
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Chinese (zh)
Inventor
黄栋杰
张军营
赵富贵
李新春
李若伟
黄嘉鹏
李若慧
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Individual
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Priority to CN201610700717.6A priority Critical patent/CN106265104A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24Phosphorous; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • A61K8/21Fluorides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22Peroxides; Oxygen; Ozone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26Aluminium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The present invention provides the material of a kind of tooth-whitening, test kit, and uses this material or the method for test kit tooth-whitening.The test kit of the present invention comprises following four kinds of reagent: etching agent, desiccant, binding agent and glazing agent.The test kit of the present invention can further include brightening agent and/or opaque resin.Present invention also offers the veneer of a kind of tooth-whitening.

Description

The material of a kind of tooth-whitening and method
Technical field
The present invention relates to dental prosthetics and repair field, relate to the compositions of tooth-whitening, test kit and tooth-whitening Method.
Background technology
Nowadays, when material life improves constantly when, social business activity increases, and people are to beautiful pursuit the most more refinement Micro-, have the more and more people of the pure white beautiful tooth of a bite and value.But a lot of people because dental plaque, tooth are yellow, creamy white the most just and Worried.Just because of this, the beauty treatment of tooth is also risen in oral cavity industry advantage.Existing tooth-whitening method has baking-ceramic tooth, full porcelain Veneer, operating time length relatively big to the removing amount of natural teeth, need anesthesia, expensive, adhesive technology is required higher, and And periodontal may be had a certain impact.
In prior art, by also having following by the technology of baking-ceramic tooth, All ceramic veneer or resin veneer tooth-whitening Shortcoming.
It is an object of the invention to provide method and the material of a kind of tooth-whitening, solve current oral cavity industry at tooth whitening On some shortcomings, the most expensive, ins and outs are loaded down with trivial details, the shortcoming overcoming prior art said method, whitening of the present invention Method and the material of tooth are little to natural teeth removing amount, and the operating time is short, it is not necessary to anesthesia, network minimal, adaptation is optimal.Operation Succinct convenient.
Summary of the invention
The present invention provide a kind of tooth-whitening material agents box, by the method for this material agents box tooth-whitening and The tooth veneer prepared with this material agents box.The tooth-whitening test kit of the present invention for various dental plaques, tooth Huang, creamy white is the most just Designed by normal crowd.It is coated with last layer material of the present invention at tooth surface, irradiates with light-solidified lamp and can solidify for 10 seconds, effect energy Keep more than 1 year, wear-resisting, ethanol-tolerant, acid-alkali-corrosive-resisting, there is good luster, the feature of the tooth body that do not weares and teares.Also dependent on oneself Hobby select different color and luster.Tooth-whitening test kit of the present invention is made up of etching agent, desiccant, binding agent and glazing agent, can To sell with nested form, it is also possible to separately sell.
On the one hand, the present invention provides the test kit of a kind of tooth-whitening, is characterised by, it comprises following four kinds of reagent: acid Erosion agent, desiccant, binding agent and glazing agent.In the present invention, described etching agent is can to obtain on the conventional use of market of dentistry Enamel etching agent, be to make dental surface demineralization, coarse or make the acidic formulation that dummy tissue surface is coarse.Enamel acid What erosion agent was conventional is more than 30% phosphoric acid, preferably 37% phosphate aqueous solution or gel, it is also possible to be that Fluohydric acid. forms with hydrochloric acid Mixing etching agent, it is highly preferred that the HCl volume ratio=50:50 of the HF and 38% of 47% in mixing etching agent.In the present invention, Described is the desiccant that can obtain on the conventional use of market of dentistry at desiccant.In the present invention, described at binding agent it is The binding agent that can obtain on the conventional use of market of dentistry, includes but not limited to following one or more: zinc phosphate water valve Spit of fland;Research of Zinc Polycarboxylic Cement;Glass ionomer;Duplex transportation binding agent;Resin modified glass ionomer cement;Colloid Aluminium-magnesium silicate;Silica sol.The addition of binding agent is pressed with binding agent and glazing agent in binding agent and glazing agent compositions Weight ratio 1:1~5 amount add in compositions.In the present invention, described glazing agent is synthetic resin, includes but not limited to contain One or more in fluororesin, such as politef, silicone resin, oil-soluble polyethylene, it is also possible to be agarose and phosphorus Acid calcium, calcium carbonate or the aqueous solution of calcium nitrate, pH value is 6.0-7.5, the amount of agarose and calcium salt than for 1g:0.05mol~ 0.30mol.Glazing agent of the present invention can also is that the aqueous solution of waterglass, sodium tetraborate and sodium hydroxide, described waterglass etc. Effect is the Na of stoichiometric proportion2O and SiO2, sodium tetraborate is equivalent to the Na of stoichiometric proportion2O and B2O3, sodium hydroxide is equivalent to The Na of stoichiometric proportion2O, its proportioning (wt%) is as follows: Na2O:SiO2:B2O3=(10~15): (35~45): (10~20).Root According to needs, in glazing agent, add brightening agent and/or opaque resin.Selectable brightening agent include but not limited to following one or Several: peroxide, metal chlorite, persulfate.Peroxide include hydroperoxides, hydrogen peroxide, alkali metal and Alkaline earth metal peroxide, organic per-compounds, peroxy acid or their mixture.Alkali and alkaline earth metal ions peroxide Compound includes lithium peroxide, potassium peroxide, sodium peroxide, Magnesium dioxide, zinc peroxide, calper calcium peroxide, Barium dioxide and mixes Compound.Other peroxide includes perborate, urea peroxide and mixture thereof.Suitably metal chlorite includes chlorous acid Calcium, barium chlorite, zinc chlorite, magnesium chlorite, lithium chlorite, sodium chlorite and potassium chlorite.The amount adding brightening agent is base About 1wt.%-about 10wt.% in composition total weight.
On the other hand, the present invention provides a kind of method of tooth-whitening, comprises the following steps:
A. acid etching: etching agent is coated enamel;
B. rinse: washing time >=etching time;
C. it is dried: use desiccant, makes enamel relatively be dried but without Chalk phenomenon;
D. mixing: binding agent of the present invention and glazing agent of the present invention are mixed to get whitening by weight 1:1~5 Tooth composite;
E. the tooth-whitening compositions that application step d obtains: tooth surface even spread one layer;
F. photocuring: veneer beauty treatment material photocuring is complete, to form good mixed layer.
Brightening agent and/or opaque resin can be mixed in step d.
Preferably, the method for a kind of tooth-whitening that the present invention provides comprises the following steps:
A. acid etching: etching agent is coated enamel, etching time is generally less than the l5 second.
B. rinse;High pressure water washing time >=etching time.
C. it is dried: use desiccant, makes enamel relatively be dried but general without Chalk phenomenon.
D. mixing: binding agent of the present invention and glazing agent are mixed to get tooth-whitening combination by weight 1:1~5 Thing.
E. color is selected: the mixture obtained in step d is mixed into brightening agent and/or opaque resin.
F. coating tooth-whitening compositions of the present invention: the tooth-whitening obtained in one layer of step d of tooth surface even spread or e Compositions, thickness about 0.05mm-0.3mm, stand after coating fully.
G. photocuring: photocuring, preferably about 10 seconds hardening time.Veneer beauty treatment material of the present invention answers photocuring complete, To form good mixed layer.
Fourth aspect, the present invention provides veneer of a kind of tooth-whitening and preparation method thereof, the system of the veneer of tooth-whitening For comprising the following steps:
A. tooth mould is prepared.
B. binding agent of the present invention and glazing agent are mixed to get tooth-whitening compositions by weight 1:1~5.
Select different color and luster opaque resin the most as required, be mixed in the mixture that step b obtains.
D. the tooth-whitening compositions that step b or c obtain being coated on tooth die surface, even spread, thickness is preferred About 0.05mm-0.3mm, stands after coating fully.
E. photocuring: photocuring, makes veneer beauty treatment material answer photocuring complete, to form good mixed layer.
F. solidification mixed layer is departed from from tooth mould, obtain tooth veneer.
The tooth-whitening material of the present invention is little to natural teeth removing amount, and the operating time is short, and hardening time is short, it is not necessary to anesthesia, Network minimal, adaptation is optimal.Operation is succinct convenient.The tooth-whitening material of the present invention, use tooth-whitening material of the present invention are beautiful The method of changing tooth, the veneer prepared with the tooth-whitening material of the present invention are wear-resisting, ethanol-tolerant, acid-alkali-corrosive-resisting, have gloss Good, the feature of the tooth body that do not weares and teares, effect can keep more than 1 year.
Detailed description of the invention
The following examples are simply to illustrate that the present invention rather than limit the scope of the invention in any way. All material used in embodiment is all commercially available on market arriving.
Embodiment 1 operates according to the following steps:
A. acid etching: dip in the phosphoric acid of 30% high concentration with cotton pellet, coats enamel, etching time l0 second.
B. rinse;10 seconds high pressure water washing time.
C. it is dried: use desiccant, makes enamel relatively be dried but general without Chalk phenomenon.
D. by Barium dioxide 0.5 gram, glass ionomer 1 gram, silica sol 1 gram, fluorine resin 8 grams, mixing.
E. mixture step d obtained is at tooth surface even spread one layer, thickness about 0.2mm, and coating is rear quiet Put 20 seconds.
F. photocuring: cure times 10 seconds.This veneer beauty treatment material answers photocuring complete, to form good mixed layer.
Embodiment 2 operates according to the following steps:
Dip in the phosphoric acid of more than 30% high concentration with cotton pellet, coat enamel, etching time 8 seconds.Use high pressure water washing 12 seconds time.Use desiccant, make enamel relatively be dried but general without Chalk phenomenon.By zinc chlorite 0.3 gram, compound tree Lipid binding agent 4 grams, silicone resin 10 grams, mixing.By the mixture that obtains at tooth surface even spread one layer, thickness 0.15mm Left and right, stands 15 seconds after coating fully.Photocuring: cure times 12 seconds.This veneer beauty treatment material answers photocuring complete, with shape Become good mixed layer.
Embodiment 3 operates according to the following steps:
Dipping in 3 mixing etching agents with cotton pellet, wherein the HCl volume ratio=50:50 of the HF and 38% of 47%, coats dentium nitor Matter, etching time 10 seconds.With 12 seconds high pressure water washing time.Use desiccant, make enamel relatively be dried but general without white Chalk phenomenon.Preparing the aqueous solution 10 grams of waterglass, sodium tetraborate and sodium hydroxide, wherein said waterglass is equivalent to chemistry meter The Na of amount ratio2O and SiO2, sodium tetraborate is equivalent to the Na of stoichiometric proportion2O and B2O3, sodium hydroxide is equivalent to stoichiometric proportion Na2O, its proportioning (wt%) is as follows: Na2O:SiO2:B2O3=10:40:15.Add veegum 2 grams, obtain whitening Tooth mixture.The mixture obtained is stood 15 the most afterwards in tooth surface even spread one layer, thickness about 0.18mm, coating Second.Photocuring: cure times 12 seconds.This veneer beauty treatment material answers photocuring complete, to form good mixed layer.
Embodiment 4 operates according to the following steps:
Dipping in 3 mixing etching agents with cotton pellet, wherein the HCl volume ratio=50:50 of the HF and 38% of 47%, coats dentium nitor Matter, etching time 10 seconds.With 12 seconds high pressure water washing time.Use desiccant, make enamel relatively be dried but general without white Chalk phenomenon.Preparing the aqueous solution 10 grams of agarose and calcium phosphate, calcium carbonate or calcium nitrate, pH value is 6.0-7.5, agarose with The amount of calcium salt is than for 1g:0.30mol.Add zinc phosphate cement 3 grams, obtain tooth-whitening mixture.The mixture that will obtain At tooth surface even spread one layer, thickness about 0.18mm, after coating fully, stand 15 seconds.Photocuring: cure times 12 seconds. This veneer beauty treatment material answers photocuring complete, to form good mixed layer.
Embodiment 5 operates according to the following steps:
Prepare tooth mould.With the phosphoric acid dip tooth mould 10 seconds of more than 30% high concentration, rinse with water, desiccant dryness. By calper calcium peroxide 2 grams, duplex transportation binding agent 4 grams, silicone resin 10 grams mixing.By the mixture that obtains on tooth mould all Even coating one layer, thickness about 0.12mm, stand 1 minute.Photocuring 30 seconds.This veneer beauty treatment material answers photocuring complete, with Form good mixed layer.Solidification mixed layer is departed from from tooth mould, obtains tooth veneer.
Embodiment 6 bond strength test
The tooth through whitening process to embodiment 3 measures the bonding of binding agent on dental brackets assembly as follows Intensity.The circular rustless steel wire loop of 0.50mm is snapped under the occlusal surface tie wings of bracket.Use tester MTS Systems, with shearing/separation mode plus load, until bracket departs from from tooth.With 5 millimeters of speed per minute pulls even Receive the wire rod of tester.Maximum power is recorded as the bonding strength of bracket.Bond area is normalized by meansigma methods, and And be unit record with MPa (MPa).Test to embodiment 1-4 whitening layer meets industry requirement.
Embodiment 7 intensity test
Evaluate comprcssive strength by the following method: the first mixture sample injections in embodiment 5 is the glass of 4mm to internal diameter In glass pipe.End with organosilicon plug glass tubing.The glass tubing making filling bears the pressure of 0.275 MPa (MPa) also Keep 5 minutes, irradiate glass tubing 80 seconds by XL 1500 cure lamp, and glass tubing is placed on KULZER UniXS (Kulzer, Inc., Germany) in lamp box 180 seconds.In five such cured sample being cut into 8mm length and putting into the water of 37 DEG C 1 day.Root According to iso standard 7489, use the INSTRON universal testing machine run with the chuck speed of 1 millimeter (mm/min) per minute (Instron Corp., Canton, MA) measures comprcssive strength.The meansigma methods of 5 retests is recorded as result.Test knot Fruit meets industry requirement.

Claims (8)

1. a test kit for tooth-whitening, is characterised by, it comprises following four kinds of reagent: etching agent, desiccant, binding agent and Glazing agent.
The test kit of tooth-whitening the most according to claim 1, is characterised by, it comprises brightening agent and/or opaque resin further.
3., according to the test kit of the tooth-whitening of claim 1 or 2, wherein said etching agent is the phosphoric acid of more than 30% high concentration Or the mixing etching agent that Fluohydric acid. forms with hydrochloric acid.
4., according to the test kit of the tooth-whitening of claim 1 or 2, wherein said binding agent includes but not limited to following one Or several: zinc phosphate cement, Research of Zinc Polycarboxylic Cement, glass ionomer, duplex transportation binding agent, resin modified glass Glass ionomer cement, veegum, silica sol.
5., according to the test kit of the tooth-whitening of claim 1 or 2, wherein said glazing agent is selected from fluorine resin, silicone tree Fat, oil-soluble polyethylene synthetic resin in one or more, or waterglass, sodium tetraborate and sodium hydroxide is water-soluble Liquid, or agarose and the aqueous solution of calcium nitrate.
6. a method for tooth-whitening, comprises the following steps:
A. acid etching: coat enamel with etching agent;
B. rinse: washing time >=etching time;
C. it is dried: use desiccant, makes enamel relatively be dried but without Chalk phenomenon;
D. mixing: glazing agent described in binding agent described in claim 4 and claim 5 is mixed to get U.S. by weight 1:1~5 White tooth composite;
E. the tooth-whitening compositions that application step d obtains: tooth surface even spread one layer;
F. photocuring: make veneer beauty treatment material photocuring, to form good mixed layer.
The method of a kind of tooth-whitening the most according to claim 6, is characterised by, adds brightening agent and/or hide color in step d Agent.
8. a veneer for tooth-whitening, is characterised by, it is prepared by method below:
A. tooth mould is prepared;
B. glazing agent described in binding agent described in claim 4 and claim 5 is mixed to get whitening tooth by weight 1:1~5 Tooth compositions;
C. select brightening agent and/or different color and luster opaque resin, be mixed in the mixture that step b obtains;
D. the tooth-whitening compositions that step b or c obtain is coated on tooth die surface, even spread, thickness 0.05mm- About 0.3mm, stands after coating fully;
E. photocuring: photocuring, makes veneer beauty treatment material answer photocuring complete, to form good mixed layer;
F. solidification mixed layer is departed from from tooth mould, obtain tooth veneer.
CN201610700717.6A 2016-08-22 2016-08-22 The material of a kind of tooth-whitening and method Pending CN106265104A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107308077A (en) * 2017-07-04 2017-11-03 湖南云从科技有限公司 A kind of formulation of tooth-paste of clean tooth-whitening and preparation method thereof
CN112451155A (en) * 2020-12-28 2021-03-09 山西米兔斯美容管理有限公司 Method for physical noninvasive tooth beautifying and whitening veneering by adopting digital material manual covering
CN113520655A (en) * 2021-07-07 2021-10-22 福建省美蒂国际发展有限公司 Method for beautifying teeth through nano-tooth carving

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Publication number Priority date Publication date Assignee Title
CN102499765A (en) * 2011-11-08 2012-06-20 郑雷 Tooth cosmetic veneering method
CN103751029A (en) * 2013-12-13 2014-04-30 中国医学科学院生物医学工程研究所 Preparation method and application of novel tooth whitening repairing agent
CN105456039A (en) * 2015-12-15 2016-04-06 江苏乘鹰新材料股份有限公司 Visible light cured dental restorative composition and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN102499765A (en) * 2011-11-08 2012-06-20 郑雷 Tooth cosmetic veneering method
CN103751029A (en) * 2013-12-13 2014-04-30 中国医学科学院生物医学工程研究所 Preparation method and application of novel tooth whitening repairing agent
CN105456039A (en) * 2015-12-15 2016-04-06 江苏乘鹰新材料股份有限公司 Visible light cured dental restorative composition and preparation method thereof

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Title
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徐恒昌: "《口腔材料学》", 31 December 2013, 北京大学医学出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107308077A (en) * 2017-07-04 2017-11-03 湖南云从科技有限公司 A kind of formulation of tooth-paste of clean tooth-whitening and preparation method thereof
CN112451155A (en) * 2020-12-28 2021-03-09 山西米兔斯美容管理有限公司 Method for physical noninvasive tooth beautifying and whitening veneering by adopting digital material manual covering
CN113520655A (en) * 2021-07-07 2021-10-22 福建省美蒂国际发展有限公司 Method for beautifying teeth through nano-tooth carving

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Application publication date: 20170104