CN105451627B - Photoimaging is popped one's head in - Google Patents
Photoimaging is popped one's head in Download PDFInfo
- Publication number
- CN105451627B CN105451627B CN201380078789.6A CN201380078789A CN105451627B CN 105451627 B CN105451627 B CN 105451627B CN 201380078789 A CN201380078789 A CN 201380078789A CN 105451627 B CN105451627 B CN 105451627B
- Authority
- CN
- China
- Prior art keywords
- mentioned
- motor
- optical fiber
- rotation
- light path
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000007246 mechanism Effects 0.000 claims abstract description 139
- 239000013307 optical fiber Substances 0.000 claims abstract description 132
- 239000000523 sample Substances 0.000 claims abstract description 87
- 230000003287 optical effect Effects 0.000 claims description 46
- 239000012530 fluid Substances 0.000 claims description 20
- 230000008859 change Effects 0.000 claims description 12
- 230000002093 peripheral effect Effects 0.000 claims description 8
- 239000000835 fiber Substances 0.000 claims description 6
- 230000008520 organization Effects 0.000 claims description 5
- 230000005611 electricity Effects 0.000 claims description 2
- 230000008450 motivation Effects 0.000 claims 1
- 230000005540 biological transmission Effects 0.000 abstract description 15
- 241001222009 Beamys Species 0.000 abstract description 4
- 238000003745 diagnosis Methods 0.000 abstract description 3
- 230000000644 propagated effect Effects 0.000 abstract description 2
- 239000000203 mixture Substances 0.000 description 18
- 238000002834 transmittance Methods 0.000 description 13
- 230000005855 radiation Effects 0.000 description 10
- 238000000034 method Methods 0.000 description 7
- 238000004458 analytical method Methods 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 238000004804 winding Methods 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 239000011737 fluorine Substances 0.000 description 3
- 229910052731 fluorine Inorganic materials 0.000 description 3
- 238000003384 imaging method Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000011347 resin Substances 0.000 description 3
- 229920005989 resin Polymers 0.000 description 3
- FHQVHHIBKUMWTI-ZCXUNETKSA-N 1-palmitoyl-2-oleoyl phosphatidylethanolamine Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCCN)OC(=O)CCCCCCC\C=C/CCCCCCCC FHQVHHIBKUMWTI-ZCXUNETKSA-N 0.000 description 2
- 229920006359 Fluoroplast Polymers 0.000 description 2
- 238000005481 NMR spectroscopy Methods 0.000 description 2
- 241000209094 Oryza Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000002059 diagnostic imaging Methods 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 230000010355 oscillation Effects 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 229920002545 silicone oil Polymers 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- 238000009987 spinning Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 230000003746 surface roughness Effects 0.000 description 2
- 238000003325 tomography Methods 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 241001269238 Data Species 0.000 description 1
- 239000005662 Paraffin oil Substances 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000004323 axial length Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000013036 cure process Methods 0.000 description 1
- 238000012631 diagnostic technique Methods 0.000 description 1
- 230000005489 elastic deformation Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000010687 lubricating oil Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 208000007578 phototoxic dermatitis Diseases 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000002310 reflectometry Methods 0.000 description 1
- 239000005871 repellent Substances 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/0209—Low-coherence interferometers
- G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/22—Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
- A61B2562/225—Connectors or couplings
- A61B2562/228—Sensors with optical connectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- General Physics & Mathematics (AREA)
- Endoscopes (AREA)
- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
Abstract
There is provided a kind of in OCT image diagnosis probe, the rotation of rotating part can be prevented uneven or axle runout, friction, rotation transmission delay by reducing the generation of rotation transmission delay or torque loss etc., and in the scanning for axially carrying out certain length, obtain the 3-D scanning type photoimaging probe of three-dimensional observation image.It is configured with substantially same line and light is propagated between the tip side and rear side of probe and non-rotatable fixed optical fiber is configured to, rotation driving is carried out and beamy first light path converting mechanism, the rotation optical fiber by motor progress rotation driving and the second light path converting mechanism for carrying out rotary emission to light towards the first light path converting mechanism on substantially radial direction, it is made up of this, results in the three dimensional viewing image of high image quality.
Description
Technical field
The present invention relates to be used to three-dimensionally read in the light of subject reflection and be observed in Medical Devices etc. three
Tie up sweep type photoimaging probe.
Background technology
Diagnostic imaging technology (photoimaging technology) is the technology being widely used at the scene such as device for mechanical, medical treatment.For example,
Manufacture scene at medical scene or precision equipment etc., as the gimmick of diagnostic imaging, except general shooting observation and ultrasound
Ripple diagnostic device, the X ray CT that can be shot to faultage image and three-dimensional tomographic image, nuclear magnetic resonance, make use of light
Gan Wataru OCT image (Guang Gan Wataru tomographies) etc. mode be studied and apply flexibly.In recent years, it is disconnected for the faultage image, three-dimensional
Tomographic image photograph, resulted in these modes most trickle photographs OCT image diagnostic techniques exploitation especially by
To concern.
It is the near infrared ray of 1300nm (nanometer) left and right as light source that wavelength is used OCT image more, and near infrared ray for
Live body is Non-Invasive, and it is short to be additionally, since wavelength ratio ultrasonic wave, therefore spatial resolution is superior.Also, due to that can reach
The spatial resolution of about 10 μm (micron) [less than 1/the 10 of diagnostic ultrasound equipment], it is therefore contemplated that by tomography side
Formula is embedded in endoscope, especially expect to be applied flexibly found at medical scene, the stomach of diagnosis and treatment human body, small intestines,
The affected part in the blood vessel portions such as Dong Veins streams.The representative construction of OCT endoscopes of the OCT image technology has been applicable for example such as patent document 1
It is shown.
In addition, in OCT endoscopes shown in patent document 1, as shown in Fig. 8 in the document, the revolving force of motor is situated between
Rotary shaft is transferred to by band, and via the flexible axial lens list of the compositions such as the optical fiber by passing through in the optic sheath of tubulose
Member transmission.Therefore, because the friction of the inner peripheral surface and flexible axle of optic sheath, produces abrasive dust sometimes.Further, since above-mentioned flexibility
The friction of axle, flexure, elastic deformation of distortion and above-mentioned band etc., can produce uneven rotating speed, rotation transmission delay, torque loss
Variation etc., therefore, the parsing anamorphose obtained, it is impossible to obtain required spatial resolution.In addition, passing through this composition
Although resulting in the two-dimensional ct image shown in Figure 26 in document, 3-D view can not be obtained.
It is the interior of ring-type guiding probe in the publication shown in Fig. 1 in addition, in OCT endoscopes shown in patent document 2
Portion inserts elongated tubular probe, probe interior have can rotate and slide and optics connection optical fiber or cored wire, make
Above-mentioned fiber spinning and in the literature shown in Fig. 3 length direction movement, bodily tissue is irradiated, observation analysis diagram as
OCT three dimensional vision systems.But this composition be due to the inner peripheral surface of probe the problem of exist with the friction of drive shaft outer peripheral face and
Produce abrasive dust.Further, since the friction of drive shaft, flexure, distortion, can produce uneven rotating speed, rotation transmission delay, torque loss
Variation etc., therefore, the parsing anamorphose obtained, it is impossible to obtain required spatial resolution.
In addition, in invention described in patent document 3, speculum to be directly linked to the motor in the document shown in Fig. 2
Rotary shaft top.But, although the faultage image of two dimension is resulted in using the speculum of rotation by this composition, not
Result in the image of three-dimensional.
Prior art literature
Patent document
Patent document 1：No. 3885114 publications of Japanese Patent No.
Patent document 2：No. 4520993 publications of Japanese Patent No.
Patent document 3：No. 4461216 publications of Japanese Patent No.
The content of the invention
Invent problem to be solved
The present invention be in view of above-mentioned conventional situation and complete, its problem is to realize a kind of photoimaging probe, the light
Imaging generation of the probe by mitigation rotation transmission delay, torque loss etc., prevents from carrying out light the rotation of rotary emission
The rotation inequality of mechanism, the runout of axle, friction, rotation transmission delay, and not only can also be carried out axially in direction of rotation
The scanning of certain length, results in the observation image of three-dimensional.
Method for solving problem
In order to which a method for solving above-mentioned problem is：Used in the photoimaging for guiding the light for injecting tip side rearward
In probe, it is configured with substantially same line：Fixed optical fiber, for the propagation light between the tip side and rear side of probe
It is configured to non-rotatable, and is built in the probe of generally tubular；First light path converting mechanism, positioned at the top of fixed optical fiber
Side, is driven in rotation by the first motor, the ray on substantially radial direction；Light-metering is rotated fine, positioned at above-mentioned fixation
Between optical fiber and above-mentioned first light path converting mechanism, pass through rotating optical connector (optical rotary joint) and above-mentioned fixed sidelight
Fine optics connection, is driven in rotation by the second motor；Second light path converting mechanism, on the top of above-mentioned rotation optical fiber
Side, makes light path tilt minute angle relative to pivot, and carries out rotary emission towards the first rotating mechanism, and the first light path turns
Converting mechanism is in radial direction ray, and the second light path converting mechanism makes the rotation angle of light axially varying, thus,
3-D scanning can be carried out.
Invention effect
According to the present invention, in the probe of endoscope apparatus etc., optical fiber will not rub, rotation transmission delay, torque loss
Deng generation mitigate.Moreover, independently being rotated by the first light path converting mechanism and the second light path converting mechanism, substantially half
Footpath direction and the two central axial directions intentionally change the rotation angle of light, thereby, it is possible to obtain three in OCT endoscopes
The high observation image of the spatial resolution of dimension.
Brief description of the drawings
The profile that Fig. 1 pops one's head in for the photoimaging of the first embodiment of the present invention.
The second motor pie graph that Fig. 2 pops one's head in for the photoimaging of first embodiment.
The rotational scan range explanation figure that Fig. 3 pops one's head in for the photoimaging of first embodiment.
The second light path converting mechanism explanation figure that Fig. 4 pops one's head in for the photoimaging of first embodiment.
The rotational scan range explanation figure that Fig. 5 pops one's head in for the photoimaging of first embodiment.
The 3-D scanning range specification figure that Fig. 6 pops one's head in for the photoimaging of first embodiment.
Fig. 7 is the guiding probe explanation figure for having used the photoimaging of first embodiment to pop one's head in.
Fig. 8 is the endoscopic images formation picture of device for having used the photoimaging of first embodiment to pop one's head in.
The profile that Fig. 9 pops one's head in for the photoimaging of second embodiment of the present invention.
The second motor pie graph that Figure 10 pops one's head in for the photoimaging of second embodiment.
The profile that Figure 11 pops one's head in for the photoimaging of third embodiment of the present invention.
The rotational scan range explanation figure that Figure 12 pops one's head in for the photoimaging of the 3rd embodiment.
The 3-D scanning range specification figure that Figure 13 pops one's head in for the photoimaging of the 3rd embodiment.
The rotating optical connector profile that Figure 14 pops one's head in for the photoimaging of the 3rd embodiment.
The second light path converting mechanism explanation figure that Figure 15 pops one's head in for the photoimaging of the 3rd embodiment.
The profile that Figure 16 pops one's head in for the photoimaging of the 4th embodiment of the present invention.
Profile when Figure 17 bends for the photoimaging probe of the 4th embodiment.
The pulses generation portion explanation figure for the first motor that Figure 18 pops one's head in for the photoimaging of the 4th embodiment.
The pulses generation portion explanation figure for the second motor that Figure 19 pops one's head in for the photoimaging of the 4th embodiment.
The first and second light path converting mechanism explanation figure that Figure 20 pops one's head in for the photoimaging of the 4th embodiment.
The time diagram for the motor pulses that Figure 21 pops one's head in for the photoimaging of the 4th embodiment.
The rotational scan range explanation figure that Figure 22 pops one's head in for the photoimaging of the 4th embodiment.
The rotational scan range explanation figure that Figure 23 pops one's head in for the photoimaging of the 4th embodiment.
The 3-D scanning range specification figure that Figure 24 pops one's head in for the photoimaging of the 4th embodiment.
The rotating optical connector profile that Figure 25 pops one's head in for the photoimaging of the 5th embodiment of the present invention.
The enlarged drawing for the clutch shaft bearing that Figure 26 pops one's head in for the photoimaging of the 5th embodiment.
The enlarged drawing for the clutch shaft bearing that Figure 27 pops one's head in for the photoimaging of the 5th embodiment.
The enlarged drawing for the second bearing that Figure 28 pops one's head in for the photoimaging of the 5th embodiment.
Embodiment
The 3-D scanning type photoimaging of present embodiment with probe fisrt feature be：In the light by tip side is injected backward
In the photoimaging probe of square side guiding, it is configured with substantially same line：Fixed optical fiber, in order to the tip side of probe with
Light is propagated between rear side and is configured to non-rotatable；First light path converting mechanism, positioned at the tip side of fixed optical fiber, passes through
First motor is driven in rotation, the ray on substantially radial direction；Optical fiber is rotated, positioned at fixed optical fiber and first
Between light path converting mechanism, it is connected by rotating optical connector (optical rotary joint) with fixed optical fiber optics, passes through second
Motor is driven in rotation；Second light path converting mechanism, in the tip side of rotation optical fiber, makes light path incline relative to pivot
Oblique minute angle simultaneously carries out rotary emission towards the first light path converting mechanism.
According to this composition, the light for being sent to rotation optical fiber by fixed optical fiber from rear, the first light path turns
Converting mechanism rotates and radially light is reflected in a two-dimensional manner, and the second light path converting mechanism rotates and in light
Release direction change light relative to the angle of pivot, thus, it is possible to carry out three dimensional viewing, and result in space
The three-dimensional observation image of high resolution.
As second feature, the composition used is：The rotary shaft of above-mentioned first motor is hollow shape, is equipped with
One light path converting mechanism, and rotate optical fiber and rotate against and run through hollow hole freely, the rotary shaft of the second motor
For hollow shape, above-mentioned rotation optical fiber is fixed with the hole and it is rotated.
, can be electronic in rear the first motor of configuration relative to the first light path converting mechanism and second according to this composition
Machine, therefore the distribution of these motor is not present in the tip side of the first light path converting mechanism, so, light will not be wired
Block, therefore, it is possible to be radiated on 360 degree of directions, and result in the complete three dimensional viewing image of no missing.
As third feature, it is configured to：Above-mentioned first motor is located at than above-mentioned first light path converting mechanism close to top
The position of side, its rotary shaft is assemblied in by above-mentioned first light path converting mechanism, and the rotary shaft of the second motor is hollow shape
Shape, above-mentioned rotation optical fiber is fixed with the hole and it is rotated.
According to this composition, the first motor does not need quill shaft, can be constituted motor with less diameter, thus it is possible to
It is enough that endoscope-use probe is configured very thin.
As fourth feature, it is configured to：Above-mentioned first motor or above-mentioned second motor at least any one to use
The ultrasonic motor of piezoelectric element or electrostriction element, rotary shaft is rotatably run through is located at substantially polygon prism
Can vibrating member approximate centre centre bore, herein can the centre bore of vibrating member have towards the slit portion that extends outside, will
Laminal piezoelectric element with electrode be attached at it is above-mentioned can vibrating member outer peripheral face, to produce independent whirling vibration respectively
Mode apply successively in the above-mentioned piezoelectric element of the side of above-mentioned slit and the above-mentioned piezoelectric element of opposite side of above-mentioned slit
Voltage, thus carries out rotation driving to rotary shaft.
According to this composition, can vibrating member there is slit, thus can produce elastic force simultaneously between vibrating member and rotary shaft
Stable frictional force is produced, and voltage separately is applied to piezoelectric element in the both sides of slit jaw, thus, with slit jaw
For boundary, the whirling vibration such as mirror image is produced in the both sides of slit, therefore, it is possible to it is small can vibrating member produce sufficiently large rotation
Power simultaneously carries out rotation driving to the first or second light path converting mechanism, thus it is possible to access, acquisition is compact and spatial resolution is high
Three dimensional viewing image endoscope probe.
As fifth feature, the first light path converting mechanism being driven in rotation by above-mentioned first motor is by relative to rotation
The speculum that turning center has the general plane at inclination angle is constituted.
According to this composition, the first small-sized light path converting mechanism can be constituted, and can fully play high reflectance, is obtained
Obtain compact and high spatial resolution three dimensional viewing image.
As sixth feature, above-mentioned first light path converting mechanism is rotatable speculum, and reflecting surface is barrel surface.
According to this composition, larger range of three dimensional viewing image can be axially being obtained.
As seventh feature, the second light path converting mechanism being driven in rotation by above-mentioned second motor is by with relative
Constituted in the prism of the general plane of pivot small skew.
According to this composition, the second small-sized light path converting mechanism can be constituted, and it is saturating fully to play high light
Rate and condenser performance are penetrated, compact and high spatial resolution three dimensional viewing image is resulted in.
As eighth feature, above-mentioned second light path converting mechanism use have on top inclined substantially sphere prism,
Or substantially semi-spherical shape a part have general plane reflecting surface globe lens.
According to this composition, the second light path converting mechanism can play sufficiently high light transmittance and condenser performance, and energy
Enough obtain compact and high spatial resolution three dimensional viewing image.
As ninth feature, above-mentioned rotating optical connector (optical rotary joint) has is covered in fixation across minim gap
Optical fiber with rotation optical fiber at least periphery of any one the first cover body and be covered in the first cover body across minim gap
Second cover body, has screw thread at least tangent barrel surface of above-mentioned minim gap of any one with the first cover body and the second cover body
Groove, transparent optical fluid is injected to above-mentioned minim gap.
According to this composition, the outflow of transparent fluid is prevented, leaks, ooze out, in rotating optical connector, the decay of light is pressed down
It is made seldom, obtains the high three dimensional viewing image of spatial resolution.
As tenth feature, above-mentioned rotating optical connector is configured to：In above-mentioned fixed optical fiber and above-mentioned rotation optical fiber
End face make the two opposed while slight distance is set, to by above-mentioned fixed optical fiber, above-mentioned rotation optical fiber, above-mentioned second electronic
The gap injection transparent fluid that the bearing of machine, the rotary shaft of above-mentioned second motor are constituted.
According to this composition, can the light loss in rotating optical connector portion be suppressed minimum, obtain good 3-D view.
As the 11st feature, it is configured to：With the first pulse generating mechanisms and the second pulse generating mechanisms, above-mentioned first
Pulse generating mechanisms at least rotate the pulse once produced more than once according to the anglec of rotation of above-mentioned first motor, and above-mentioned the
Two pulse generating mechanisms at least rotate the pulse once produced more than once according to the anglec of rotation of above-mentioned second motor；Have
Controlling organization, the controlling organization passes through the arteries and veins from above-mentioned first pulse generating mechanisms and above-mentioned second pulse generating mechanisms
Punching, to adjust the rotating speed of above-mentioned first motor and above-mentioned second motor；With the rotating speed N1 of above-mentioned first motor with it is upper
The relation for stating the rotating speed N2 of the second motor is rotated for N2=N1-X [revolutions per second] mode, thus makes light from above-mentioned
First light path converting mechanism is released with N1 [revolutions per second] rotating speed to substantially radial direction, and makes light with X [coming and going/second] speed
The releasing angle of line changes in the axial direction.
According to this composition, the radiation of light with N1 speed (such as 30 revolutions per seconds) while rotated at a high speed, while with X per second
Round (such as 1 comes and goes the/second) at a slow speed is axially changing radiation angle, being capable of helically ray, and can efficiently receiving
Collect three-dimensional data, obtain obtaining the endoscope probe of the high three dimensional viewing image of spatial resolution.
As the 12nd feature, it is configured to：Receive and produced from above-mentioned first pulse generating mechanisms and above-mentioned second pulse
The pulse of life structure, by above-mentioned controlling organization, makes the rotating speed of above-mentioned first motor and above-mentioned second motor with identical
Rotating speed rotates and is set to holding state, by the generation of commencing signal, with the rotating speed N1 of above-mentioned first motor and above-mentioned second
The rotating speed N2 of motor relation makes rotation speed change for N2=N1-X [revolutions per second] mode.
According to this composition, it can simultaneously start 3-D scanning at once with commencing signal.
Next, being illustrated referring to the drawings to the preferred embodiment of the present invention.
Embodiment 1
Fig. 1~Fig. 8 represents the embodiment 1 of the photoimaging probe of the present invention.
The profile that Fig. 1 pops one's head in for the 3-D scanning type photoimaging of the first embodiment of the present invention.By light from spy
The fixation optical fiber 1 of the lateral tip side guiding in rear end of head is inserted through in the hole of sufficiently long tubular probe 6, and solid by optical fiber
Determine part 4 to fix.
Rotation optical fiber 2 is rotatably provided with the tip side of fixed optical fiber 1.The top of optical fiber 2 is being rotated, with
Rotation optical fiber 2 is relatively independent and is rotatably equipped with the first light path converting being made up of speculum of roughly planar etc.
Mechanism 3a, 3b, is configured to by rotation in whole circumferential ray.
In addition, the second light path converting mechanism 20 is equipped with the top of rotation optical fiber 2, the second light path converting mechanism 20
Optically focused is carried out to the light come from the fixed transmission of optical fiber 1, rotated while in top orientation additional a few degrees ground direction
First light path converting mechanism 3a, 3b ray.
The slight distance of above-mentioned rotation optical fiber 2 and fixed optical fiber 1 across 5 μm (micron) left and right is opposed, includes rotation
Shadow shield 5 and optical fiber fixture 4 and constitute rotating optical connector 22, can be tieed up between rotation optical fiber 2 and fixed optical fiber 1
High-transmission rate is held, optics connection is almost carried out without loss.
In first motor 12, motor winding 7, clutch shaft bearing 9b, 9a are fixed with motor casing 8, is equipped with and turns
The hollow rotating shaft 10 of sub- magnet 11 rotates.Voltage is applied to motor winding 7 by electric wire 23, assembled in hollow rotating shaft 10
There is above-mentioned first light path converting mechanism 3.
In second motor 19, second bearing 18a, 18b, second bearing 18a, 18b rotation are equipped with motor casing 8
The second rotary shaft 13 is supported freely.In fig. 2, the second rotary shaft 13 by light press-in be opened in can vibrating member 14 approximate centre
Hole 14a, due to being continuously provided with slit 14b with hole 14a, therefore can be between the rotary shaft 13 of vibrating member 14 and second, by can
The elasticity of vibrating member 14, produces stable frictional force.
Can the periphery of vibrating member 14 be pasted with electrostriction element 15a, 15b, 15c, 15d, 15e, 15f, 15g, 15h,
Electrode 16a, 16b, 16c, 16d, 16e, 16f, 16g, 16h are formed with these electrostriction elements.These each electrodes pass through
Electric wire 17 shown in Fig. 1 carries out distribution, and is applied in voltage.Can vibrating member 14 be braked relative to second bearing 18a, 18b, letter
Single is the function that electric wire 17 also plays braking sometimes.
In Fig. 1, near the periphery of beamy first light path converting mechanism 3, the transmittance section 21 that light is transmissive to
It is assemblied in probe 6.Transmittance section 21 is made up of transparent resin or glass etc., as needed and apply for reduce surface reflection,
Improve coating of transmissivity of light etc..
Fig. 7 is the explanation figure for the guiding probe 82 for having used 3-D scanning type photoimaging to pop one's head in.Probe 82 is guided with energy
Enough the insertion stomach of human body, small intestine, the mode in bronchus etc., are formed into its diameter less than about 9 millimeters, plain with fluorine
The appropriate intensity and flexibility of resin etc..
In addition a diameter of 10mm (millimeter) of probe 6 is in the way of not opening pin hole, by solid and have below, equally
Fluoroplast pipe of flexibility etc. is constituted.In addition, there is CCD image pickup parts 83 in its top observation portion 84, throughout guiding probe 82
The intercommunicating pore for being endlong provided with referred to as forceps channel 81, photoimaging of the invention is configured to insert freely with the probe 6 of probe
Enter in the forceps channel and be taken out freely.
Fig. 8 is the pie graph for the endoscope apparatus for having used 3-D scanning type photoimaging to pop one's head in, probe 6 and guiding probe
82 are together assemblied in the main body 85 of OCT endoscope apparatus.Drive circuit 86, the second motor of motor 12 are built-in with main body
19 drive circuit 87, Guang Gan Wataru analysis units 88, image analysis computer 89, the image of CCD shootings 83 is shown in monitor 90
With the OCT 3-D views for being parsed and being made by computer 89.
From Fig. 8 motor drive circuit 86 to Fig. 1 supply electric power of the first motor 12, rotation driving first is electronic
Machine 12, voltage is applied and the second motor of rotation driving 19 from 87 pair of second motor 19 of the second motor drive circuit.
Run through the glass fibers of fixation optical fiber 1 and rotation optical fiber 2 for bending freely inside the probe 6 shown in Fig. 1
Dimension, a diameter of 0.08mm~0.4mm (millimeter) left and right used.
The second light path converting mechanism 20 shown in Fig. 1 is by being reflected light and being had the coniform of general plane portion 24
Or cylindric prism etc. is constituted, in order to improve reflectivity, surface roughness and form accuracy ground for general optics zero
Parts precision is identical or higher than its.
A diameter of 0.2mm~0.5mm (millimeter) in the hole of the hollow rotating shaft 10 shown in Fig. 1, and hollow rotating shaft 10
Material is metal or ceramic material, passes through the drawing processing realized by the mould of molten metal or the ceramic die reality before burning till
Existing extrusion process and be configured to hollow, after cure process, outer peripheral face is finished by attrition process method etc..
Next, being popped one's head in for the photoimaging of above-mentioned Fig. 1~Fig. 8 3-D scanning type, its characteristic is described in detail
Action effect.
In Fig. 8, the light such as near-infrared sent from the light source in main body 85 from guiding probe 82 in probe 6 in fixation
Optical fiber 1 by and advance.
In Fig. 1, from the supply electric power of electric wire 23, the first motor 12 is with the fixed speed of about 1800~20000rpm scopes
Rotation, and the light being directed passes through from rotating optical connector 22 and rotation optical fiber 2, is put from the second light path converting mechanism 20a
Go out, reflect in the first light path converting mechanism 3a general plane portion 24 and change in direction to certain angle direction and (be in Fig. 1
θ 1 angle), carry out rotary emission.
The light of near infrared ray further passes through from transmittance section 21, and it is left to be transmitted through 2mm~5mm (millimeter) from human epidermal
The right side, makes the light reflected from there pass through transmittance section 21 along the direction opposite with above-mentioned same light pathFirst light path converting
Mechanism 3aSecond light path converting mechanism 20aRotate optical fiber 2Rotating optical connector 22Fixed optical fiber 1, and
It is directed to Guang Gan Wataru analysis units 88.
The scanning range of the radial extent of light now, i.e. Guang Gan Wataru endoscopes as shown in figure 3, optical-fiber two-dimensional transmit
To radius about 2mm~5mm (millimeter) distance.In Fig. 1, the first light path converting mechanism 3a and 3b is to be represented by solid and broken lines
Rotation in representational two positions.
Next, electric wire 17 is passed to Fig. 2 the second motor 12 from the second motor drive circuit 87 shown in Fig. 8
Electrode 16, voltage is applied with the electrode 16a → 16b → 16c → 16d arranged order, in addition, at the same time, if to arrange
In slit 14b opposite side electrode 16e → 16f → 16g → 16h order apply voltage, then can arrow from vibrating member 44 to Fig. 2
Head direction A and arrow B produces two rotary traveling waves simultaneously.
The rotary traveling wave assigns revolving force in the way of being clamped from two directions to the surface of the second rotary shaft 13, rotates sidelight
Fibre 2, shadow shield 5, the slowly rotation of the second light path converting mechanism 20.Second motor is such a ultrasonic activation motor, is carried out
Several seconds completes the slow rotation of the degree once rotated.In addition, with slit 14b can vibrating member 44 be not necessarily one
Construction, for example, can be constituted by being laminated many sheet metals.
Then, at the second light path converting mechanism position in rotary moving as illustrated in fig. 4 to 20b, light is in rotation
First light path converting mechanism 3a, 3b reflect, and the route change certain angle of light is changed into θ 2 in figure.The light of the moment is put
It is inclined two-dimentional scope as shown in Figure 5 to penetrate scope.
Then, if the second light path converting mechanism 20 is slowly once rotated, the radiation direction of light is in 1~θ of θ 2
In the range of gradually change, so, as shown in fig. 6, the radial extent of light turn into θ 1+ θ 2 scope, carry out 3-dimensional irradiation.
In addition, by making the rotation of the first light path converting mechanism 3 carry out the scanning of 360 degree of whole weeks, but at 360 degree
Completely without setting signal line and electric wire in scanning range, thus it is possible to obtain 360 degree of distinct OCT images without missing.
Embodiment 2
Next, the embodiment 2 to the 3-D scanning type photoimaging probe of the present invention is illustrated.(reference picture 9~
Figure 10)
The 3-D scanning of second embodiment shown in Fig. 9 photoimaging probe in, the probe 6 of generally tubular it is interior
In footpath, connection tip side and rear side are fixed with by optical fiber fixture 4 and there is the fixation optical fiber 1 of sufficient length.
In the tip side of fixed optical fiber 1, rotation optical fiber 2 short enough is formed on same axle with fixed optical fiber 1,
The second light path converting mechanism 120 is provided integrally with the tip side of rotation optical fiber 2, by with rotating the same axle of optical fiber 2
Upper the second motor 19 with the second rotary shaft 13, is rotating slowly it.
Rotate optical fiber 2 and shadow shield 5, fixed optical fiber 1, the formation rotating optical connector 22 of optical fiber fixture 4, affixed side
The slight distance that optical fiber 1 and rotation optical fiber 2 separate tens of μm (micron) left and right is set, but respective section is smoothly processed
At a right angle, further, since on same axle, light can undampedly pass through between two optical fiber.
In the tip side of the second light path converting mechanism 120, the first light path converting being made up of speculum of general plane etc.
Mechanism 103 is assemblied in the first motor 112 and rotated.
In first motor 112, motor winding 107 and the are equipped with the motor casing 108a of thin-walled and cylindrical shape
One bearing 109a, 109b, clutch shaft bearing 109a, 109b are rotationally supported to the first rotary shaft 110 and rotor magnet 111, led to
The supply electric power of electric wire 123 is crossed, the first light path converting mechanism 103 is rotated.
Revolved in addition, being equipped with second bearing 18a, 18b, second bearing 18a, 18b supporting second in motor casing 108b
Rotating shaft 13.Second rotary shaft 13 be inserted through or gently press-in can vibrating member 114 hole, together constitute with the second motor with electric wire 17
19, this can the surface of vibrating member 114 be pasted with the electrostriction elements 115 of pattern electrodes 116 formd on surface.
In Figure 10, in the second motor 19, the second rotary shaft 13 is pressed into hole 114a, can vibrating member 114, with slit
114b is boundary, and electrostriction element 115a, 115b are pasted with its side, is forming electrode 116a, 116b respectively thereon.
In addition, being pasted with electrostriction element 115c, 115d in slit 114b opposite side, electrode 116c, 116d are formed.
Apply voltage from electric wire 17 with electrode 116b → 116a order, the rotary traveling wave shown in arrow C in figure is produced, and if with electricity
Pole 116d → 116c order applies voltage, then produces the rotary traveling wave in figure shown in arrow D.Second rotary shaft is from both direction
The revolving force produced by whirling vibration ripple is received, the light path converting mechanism 120 of rotation optical fiber 2 and second is rotating slowly.
The action of second embodiment and feature are roughly the same with the first embodiment shown in Fig. 1, in Fig. 9 directions of θ 1
Ray, light is from transmissive portions 21 by and by radiating.Rotated by the first motor 112 and the second motor 19, so that
Beamy scope is also the scope shown in, Fig. 6 same with Fig. 1 first embodiment.
In Fig. 9, the first rotary shaft 110 is not quill shaft, therefore, it is possible to thinner, so can be by the structure of the first motor 112
Into carefully.
Present embodiment, in the inside of the total length throughout the rear from probe 6 to top, fixed optical fiber 1 fixed and
Do not rotate, therefore friction will not be produced.Therefore, the generation of rotation transmission delay and torque loss etc. is reduced, in the absence of first
The rotating speed of light path converting mechanism 103 is uneven, results in the high spatial resolution of 10 μm (micron).
Moreover, intentionally change the radiation angle of the second light path converting mechanism 120 by being powered to the second motor 19, by
This, makes the direction change of light radiated from the first light path converting mechanism, can carry out the scanning of three-dimensional, result in space point
The high and distinct OCT three dimensional viewing images of resolution.But, in the present embodiment, the electric wire 123 of the first motor 112 can be hampered
Hinder 360 degree of scannings, a part for picture signal can also be lacked sometimes.
Embodiment 3
Next, the embodiment 3 to the 3-D scanning type photoimaging probe of the present invention is illustrated.(reference picture 11
~Figure 15)
In the photoimaging probe of the 3-D scanning of the 3rd embodiment shown in Figure 11, in the probe of generally tubular
6 inside is fixed with the fixation optical fiber 1 of the sufficient length with connection tip side and rear side by optical fiber fixture 4.Gu
Determine optical fiber 1, rotation optical fiber 2, optical fiber fixture 4, shadow shield 5 and constitute rotating optical connector 222.
In the tip side of fixed optical fiber 1, rotation optical fiber 2 short enough is located at fixing on the same axle of optical fiber 1,
The tip side of rotation optical fiber 2 is provided integrally with the second light path converting mechanism 220 for example with cylinder prism or sphere-prism,
Light is from the second light path converting mechanism relative to axle center with having a few degrees rotary emission.
Have in the tip side of the second light path converting mechanism 220 such as the first light rotated freely constituted by speculum
Road switching mechanism 103, receives the light radiated from the second light path converting mechanism and is reflected to approximate right angle direction, from transmittance section 21
By and to whole week rotary emission light.
First light path converting mechanism is by the first motor 219, the slow speed rotated once with about 0.5 second to the several seconds
Be driven in rotation, the first motor 219 by motor casing 208a, the first rotary shaft 213, can vibrating member 214, electrostriction member
Part 215, electrode 216, electric wire 17, clutch shaft bearing 218a, 218b composition, it acts the second motor 19 with second embodiment
It is identical.
Second light path converting mechanism is rotated by the second motor 212 with about 1800rpm to about 20000rpm speed
Driving.Second motor 219 is by motor casing 208b, motor winding 207, second bearing 209a, 209b, the second rotary shaft
210th, rotor magnet 211, electric wire 223 are constituted, and its action is identical with the first motor 112 of second embodiment.
In Figure 11, the reflecting surface of the first light path converting mechanism 103 is barrel surface, if from the first light path converting mechanism 220 with
Barrel surface of the angle by the light of rotary emission in the first light path converting mechanism 103 in figure shown in θ 1 reflects, then its radiation angle
Become bigger than θ 1, with θ in scheming 2 wide-angle, radiated as illustrated in fig. 12 in two dimensional range.
Then, if the first light path converting mechanism 219 is rotating slowly once, dimensionally ray as illustrated in fig. 13
And obtain 3-D view.
The surface configuration in the substantially sphere portion 225 of the second light path converting mechanism 220 is to coordinate the first light path converting mechanism
The shape of reflecting surface is appropriately designed, and substantially sphere or the surface configuration for having small curved surface compared with plane optically gathers
Photosensitiveness is good, and endoscopic observation image can be improved sometimes.
In addition, in Figure 11, the second light path converting mechanism, can also to have the second light path mechanism of sphere as shown in figure 15
With reflecting surface 324.
Figure 14 represents the profile of rotating optical connector 222.First cover body 226 separates small radius clearance covering and fixed
The periphery of either one of optical fiber 1 and rotation optical fiber 2, it is outer that the second cover body 227 separates small radius clearance covering
Either one of the part in week, the first cover body 226 and the second cover body 227 are fixed on the shadow shield of rotation, and the opposing party is fixed on non-rotation
The optical fiber fixture turned.
Two small radius clearances are about 10 μm (microns) to 30 μm (micron), and silicone oil or fluorine are injected to these gaps
The optical fluid 230 of prime system.Thus, the opposed faces of fixed optical fiber 1 and rotation optical fiber 2 are full of optical fluid 230, therefore two
Transmissivity between person is improved, and the optical loss of OCT observation devices becomes minimum, and image property is improved.
On on the first or second cover body 226,227, its barrel surface, above-mentioned two minim gaps the face of at least one
Groove is threaded, can be by rotation, to seal optical fluid 230 with spring pump identical effect and lock gap.In addition,
In the outer peripheral face of the second cover body 227 and the surface of shadow shield 5 covered with insulating course 228,229, it can prevent optical fluid 230 from oozing
Go out to outside.
Oil groove 227a is provided near the opening portion of the second cover body 227, the stage of the rotating optical connector is being assembled, at this
Oil groove 227a is coated with appropriate optical fluid 230, is subsequently placed into relief groove, thus, the air inside discharge, makes optical fluid
230 intrusions are internal.
In present embodiment, in the inside of the total length throughout the rear from probe 6 to top, fixed optical fiber 1 is visited long
Do not rotated in pin 6, therefore friction will not be produced, can prevent from rotating the generation of transmission delay and torque loss etc..
Embodiment 4
Figure 16~Figure 24 represents the embodiment 4 of the photoimaging probe of the present invention.
Figure 16~Figure 17 is the profile of the 3-D scanning type photoimaging probe of the 4th embodiment of the present invention, Figure 16
For the profile for the photoimaging probe being arranged on straight line, the section that Figure 17 pops one's head in for the photoimaging of top ends case of bending
Figure.The fixation optical fiber 1 to tip side is guided to be inserted through in the probe 6 of sufficiently long tubulose from the rear end side of probe light
The approximate centre in portion.
Rotation optical fiber 2 is rotatably provided with the tip side of fixed optical fiber 1.Rotation optical fiber 2 is drawn by optical fiber
Guide bearing 26 is rotationally supported, on its top, by the first motor 12, relatively independent and rotatably with rotation optical fiber 2
The first light path converting mechanism 3 being made up of speculum of roughly planar etc. is equipped with, is configured to make light by rotation with example
θ 1 angle is radiated to all-round direction in such as figure.First light path converting mechanism 3 is shown in 3a in figure, 3b according to its anglec of rotation.
In addition, the second light path converting mechanism 20 is equipped with the top of rotation optical fiber 2, the second light path converting mechanism 20
Optically focused is carried out to the light come from the fixed transmission of optical fiber 1, rotated while in top orientation additional a few degrees ground direction
The ray of first light path converting mechanism 3.Second light path converting mechanism 20 is shown in 20a in figure, 20b according to its anglec of rotation.
Slight distance of the above-mentioned rotation optical fiber 2 with fixed optical fiber 1 across 5 μm (micron) left and right is opposed, includes rotation
Shadow shield 5 and optical fiber fixture 4 and constitute rotating optical connector 22, can be tieed up between rotation optical fiber 2 and fixed optical fiber 1
High-transmission rate is held, optics connection is almost carried out without loss.
First motor 12 is built in probe 6, and the hollow rotating shaft 10 for being equipped with rotor magnet 11 rotates.Pass through electric wire
23 pair of first motor 12 applies voltage, is equipped with above-mentioned first light path converting mechanism 3 in hollow rotating shaft 10 and rotates it.
In second motor 19, the second rotary shaft 13 by light press-in be opened in can vibrating member 14 approximate centre hole, pass through
Can vibrating member 14 elasticity or spring, stable frictional force is produced between the second rotary shaft 13.Second motor 19
The second rotary shaft 13 by rotate optical fiber 2 be fixed on centre bore, voltage is applied by the electric wire 17 of distribution, makes the second light path
Switching mechanism 20 rotates.
The first motor 12 be provided be made up of rotary side part 25a as shown in figure 18 and affixed side part 25b the
One pulse generating mechanisms 25, in the same manner, in the second motor 19 provided with rotary side part 24a as shown in figure 19 and fixed sidepiece
The second pulse generating mechanisms 24 for dividing 24b to constitute, according to the anglec of rotation of each first and second motor, often rotate and once produce
Raw one or many pulse signal.The generation principle of these pulses uses induction coil or Hall element equimagnetic to sense
Device or the optical sensor that is made up of optical shutter and optical sensor etc..
Near the periphery of beamy first light path converting mechanism 3, as needed, the transmittance section that light is transmissive to
21 are assemblied in probe 6.As needed, substantially sphere portion 21a is formed with transmittance section 21, to release the angle of near infrared light
In the case that (θ 1 in figure) is gradually changed, injecting the angle of transmittance section, also constant mode forms sphere portion 21a.In addition, according to
Need, its wall thickness is not fixed, but makes thickness change.Transmittance section 21 is made up of transparent resin or glass etc., according to
Need and apply for reducing surface reflection, suppressing minimum by the total reflection of light and improving the coating etc. of transmissivity.
From Fig. 8 motor drive circuit 86 to Figure 16 supply electric power of the first motor 12 and the first motor 12 is entered
Row rotation driving, applies voltage from the second motor drive circuit 87 and carrys out the second motor of rotation driving 19.In addition, first is electronic
Machine 12 can adjust rotating speed by pulse signal from the first pulse generating mechanisms 25, the second motor 19 can by from
The pulse signal of second pulse generating mechanisms 24 makes rotating speed and the values match being previously set.
Next, being popped one's head in for the photoimaging of above-mentioned Figure 16~Figure 24 3-D scanning type, its feature is explained
The action effect of property.
In Fig. 7, Fig. 8, the light of near-infrared sent from the light source in main body 85 etc. is from the probe 6 in guiding probe 82
Fixation optical fiber 1 in by and advance.
In Figure 16, from the supply electric power of electric wire 23, the first motor 12 is with the fixed speed of about 1800~20000rpm scope
Degree rotation, and the light guided by fixed optical fiber 1 passes through from rotating optical connector 22 and rotation optical fiber 2, from the second light path
Switching mechanism 20a is released, and is reflected in the first light path converting mechanism 3a general plane portion and is changed in direction to certain angle
Direction (being the angle of the θ directed downwardly 1 shown in solid arrow in Figure 16), carries out rotary emission.In addition, the first light path converting mechanism
3 and second light chopper mechanism 20 rotated with identical rotating speed and when being changed into 3b and 20b position in figure, light is from the second light path
Switching mechanism 20b is released, and is reflected in the first light path converting mechanism 3b general plane portion and is changed in direction to certain angle
Direction (angle of the θ 1 upward in Figure 16 shown in dotted arrow), carries out rotary emission.Now, as shown in figure 22, light is in
Substantially coniform radiation shown in angle, θ 1, is scanned to subject.
Compared with Figure 16, Figure 20 is that the first light path converting mechanism 3 is differed with the phase angle of the second light chopper mechanism 20
The figure of the situation of 180 degree, the feelings that the first light path converting of state representation mechanism 3 and the second light chopper mechanism 20 are rotated with rotating speed
The state generated under condition.The light guided by fixed optical fiber 1 passes through from rotating optical connector 22 and rotation optical fiber 2, from figure
20 the second light path converting mechanism 20b is released, and is reflected in the first light path converting mechanism 3a general plane portion and is changed direction
To certain angle direction (angle of the θ directed downwardly 2 in Figure 20 shown in solid arrow), rotary emission is carried out.Now, such as Figure 23
Shown, the substantially coniform radiation shown in light at angle theta 2 is scanned to subject.So, different rotating speeds are entered
Go small change to rotate the first light path converting mechanism 3 and the second light chopper 20, thereby, it is possible to make the radiation angle of light
Swung in the angular range from the θ 2 shown in the θ 1 to Figure 20 and Figure 23 shown in Figure 16 and Figure 22.
Like this, the rotation angle of light in fig. 24 2 from θ 1 to θ in the range of repeat, endoscope-use probe can be
Dimensionally tested portion is scanned in the range of hollow circuit cylinder.The external diameter for the hollow circuit cylinder being scanned is about 2mm~10mm
The axial length of the scope of photoimaging scanning probe of the invention once in (millimeter), figure shown in Ls is about 2mm~10mm (millis
Rice).
The light of near infrared ray further passes through from Figure 16 transmittance section 21, and 2mm~5mm (millis are transmitted through from human epidermal
Rice) left and right, the light reflected from there is passed through transmittance section 21First light path converting mechanism 3Second light path converting machine
Structure 20Rotate optical fiber 2Rotating optical connector 22Fixed optical fiber 1, and it is directed to the dry Wataru analysis units 88 of light.
Figure 21 is that light invents the first motor 12 of imaging probe and the generation burst length figure of the second motor 19, figure
The line chart of middle upside represents the line chart of downside in the generation pulse of the first pulse generating mechanisms 25 from the first motor 12, figure
The generation pulse of the second pulse generating mechanisms 24 of the second motor 19 is represented, transverse axis represents time shaft.
Period in figure shown in " Stand by (standby) " is the first motor 12 and the one side of the second motor 19 with same
The state of the commencing signals to be scanned such as one rotating speed rotation one side.
If next, by imaging pop one's head in operator operation and send " Start (beginning) signal ", it is same with this
When, the first motor 12 is rotated with the speed (such as 30 revolutions per seconds) for being for example expressed as N pulse/secs, and is started subject
OCT perspective image datas are accumulated in computer 89.
At the same time, the second motor 19 is rotated with the speed of such as (N-1) pulse/sec (such as 29 revolutions per seconds), therefore,
As shown in figure 24, rotation angle again returns to θ 1 angle with 0.5 second after θ 1 is changed to θ 2,1 second, terminates the three of light
Dimension radiation.
In this case, computer is reciprocal secondary (secondary is one group) altogether in being read in 1~θ of θ 2 time in rotation angle
Three-dimensional data, obtain have no missing distinct three-dimensional OCT diagnostic images.Can carry out the reading of data and accumulation when
Carve, the first motor 12 and the second motor 19 are changed into " Stand by (standby) " state again, while waiting next
" Start (beginning) signal ", while being rotated.
The present invention 3-D scanning be with the application method of the further practicality of OCT probe：For example, the first stage is
The probe feeding length of the present invention is intravascular, in this case, the first motor 12 and the one side of the second motor 19 are with same rotating speed
Rotation, probe of the invention is while proceed the 360 degree of scannings of two dimension, according to the two dimensional image determination for being shown in monitor 90
The position of affected part near blood in human body in pipe.
By the first pulse generating mechanisms 25,25a from Figure 16,25b pulse signal carries out X-Y scheme as triggering
The reading of picture, and two dimensional image is shown on monitor 90 by computer disposal.
Next, in second stage, stopping the push-and-pull to probe, making probe 6 static, make the second motor 19 with for example
(N-1) the speed rotation of pulse/sec (such as 29 revolutions per seconds), carries out the three-dimensional radiation of light, OCT devices can be in monitor 90
The high 3-D view of upper display resolution, carries out the detailed observation of affected part.
It will come from the first pulse generating mechanisms 25,25a, 25b pulse signal and from the second pulse generating mechanisms 24,
3-D view, as triggering, is read in computer 89, and be shown in by the moment that 24a, 24b pulse signal both sides are issued simultaneously
On monitor 90.
Phase III is that the probe for further making the present invention is moved to the other end, is in this case also the first motor 12
Rotated with the one side of the second motor 19 with same rotating speed, probe of the invention is while proceed the 360 degree of scannings of two dimension, by two
The OCT image of dimension is shown in monitor 90.
In present embodiment, in the inside of the total length throughout the rear from probe 6 to top, fixed optical fiber 1 is visited long
Do not rotated in pin 6, therefore friction will not be produced, can prevent from rotating the generation of transmission delay and torque loss etc., in addition, rotation
Optical fiber 2 is also rotatably configured in the hole of fiber guides bearing 8 and hollow rotating shaft 10, almost without slippage loss.
Embodiment 5
Next, being subject to using Figure 25 to Figure 28 embodiments 5 popped one's head in the 3-D scanning type photoimaging of the present invention
Explanation.
In the photoimaging probe of the 3-D scanning of the 5th embodiment shown in Figure 25, in the probe 6 of generally tubular
Inside, connection tip side and rear side and with sufficient length fixation optical fiber 1 and rotation the both sides of optical fiber 2 end face quilt
Smoothly process and be processed to right angle, separate the gap of about 100 μm (micron) below (preferably for 5 μm (microns) below),
It is opposed on the same axis.
Rotation optical fiber 2 and the second rotary shaft 13 of the second motor 19 are rotated integrally, and the position of its pivot passes through
Second fore bearing 27 and the second rear side bearing 28 are accurately limited.In addition, fixed optical fiber 1 is fixed on the second rear side bearing
28, the second rear side bearing 28 accurately processed maintains fixed optical fiber 1 and the axiality of the rotation both sides of optical fiber 1
High accuracy within several μm (micron).
As needed, transparent optical fluid is injected to the gap between Figure 25 fixation optical fiber 1 and rotation optical fiber 2
230 (such as normal temperature viscosity is silicone oil, paraffin oil, the fluorine prime system fluid of 10~50 centistokes(cst)s).By injecting liquid, light passes through solid
Attenuation rate in the case of determining between optical fiber 1 and rotation optical fiber 2 is reduced to 1/10 or so, can be carried out good light and be passed
Pass.In addition, even if the gap between fixed optical fiber 1 and rotation optical fiber 2 changes, attenuation rate does not also deteriorate, therefore, it is possible to make
Performance stability.
Dynamic pressure of the inner peripheral surface of the bearing hole of clutch shaft bearing 15 shown in Figure 26 provided with for example straight type produces groove 15a, dynamic pressure
The optical fluid 18 that pressure imparting is flowed into will be produced by producing groove 15a.Thus, the second rotary shaft 13 floats and rotated, can be smooth
Ground keeps rotating speed and reduces rotating speed inequality, prevents the generation of rotary oscillation or whirling vibration, the positional precision of pivot is protected
Hold 1 μm (micron) below left and right high accuracy.
In Figure 27, the second front side bearing 27 with can the opposed face in the side dynamic pressure that has Fish bone types of vibrating member 14 produce
Groove 27b, lubricating oil or above-mentioned optical fluid 230 to inflow produce axial pressure, are axially manufacturing gap, it is to avoid contact,
Swimmingly rotated.By correspondingly manufacturing a certain amount of gap, the position restriction of axial direction is carried out.
The dynamic pressure that the bearing surface slided in the second rotary shaft 13 of the second rear side bearing 28 is threaded groove profile is produced
Groove 28a, produces pressure to the optical fluid 230 for flowing into bearing sliding surface, floats the second rotary shaft 13, swimmingly keeps turning
Speed, and rotary oscillation and whirling vibration are prevented, rotation position precision is kept well.In addition, the dynamic pressure of screw thread groove profile is produced
Groove 28a has concurrently produces the effect of seal pressure by rotation with screw pump in the same manner as, and performance locks the as by optical fluid 230
The function of the fluid strip of paper used for sealing in the gap of two rear side bearings 28.
In addition, in order to avoid enclose the second rear side bearing 28 gap optical fluid 230 flow out to it is outside or from the second axle
The danger that the surface held is oozed out, as needed, applies by dialling that fluoroplast etc. is constituted on the surface of the second rear side bearing 28
The coating of water-repellent oil, flicks optical fluid 230, prevents it from oozing out into outside.
In the present embodiment, in the inside of the total length throughout the rear from probe 6 to top, fixed optical fiber 1 is in length
Do not rotated in probe 6, therefore friction will not be produced, can prevent from rotating the generation of transmission delay and torque loss etc..
In addition, rotation optical fiber 2 is also rotatably configured in the hole of hollow rotating shaft 1, due to being damaged in the absence of slip
Lose, therefore, the rotation inequality of motor 12 is considerably less.In general opinion scale, the performance of rotating speed is by with percentage
Represent that the anglec of rotation, come what is evaluated, in the present invention, can reach 0.01% high-performance.
On the other hand, the rotation inequality of the endoscope probe of conventional optical fiber friction mode can only obtain about its 100 times with
On bad performance.
It is most important to require that performance is to improve the space of 3-D view in Fig. 8 OCT three-dimensional manipulating image diagnosing systems
Resolution ratio, and be used to realizing spatial resolution will because of the rotating speed including motor 12 uneven, hollow rotating shaft 10 runout essence
Precision and surface roughness of degree, the first light path converting element 3 and the second light path converting mechanism 20 etc..
Wherein disturbance degree greatly be motor 12 rotating speed it is uneven, therefore, in top ends built-in motor 12, and make light path
Conversion element for example can stably realize 10 μm in high precision and in the endoscope probe of the invention without the uneven rotation of rotating speed
The high three dimensions resolution ratio of (micron) below.
According to the present invention, optical fiber is rotated against in the probe of endoscope apparatus etc., therefore do not produce friction, can
Mitigate the generation of rotation transmission delay, torque loss etc., and can obtain fresh with the high spatial resolution of 10 μm (microns) below
Bright OCT analysis diagram pictures, in addition, the thickness by intentionally changing the second light path converting mechanism, can make light exist vertically
Radiated in certain limit, therefore, it is possible to obtain the observation image of three-dimensional.
Industrial applicability
The 3-D scanning type photoimaging probe of the present invention does not make the fiber spinning in long tube, but attached on the top of pipe
Closely set and have no the light path converting mechanism that speed unevenly rotates by motor, and with high-precision rotation sweep machine
Structure, thereby, it is possible to the spatial resolution as the basic performance of OCT image diagnostic device is improved to about 10 μm (micron) with
Under.And the observation of the affected part of inside of human body by 3-D scanning, can be carried out and diagnosed without carrying out incision hand to human body
Art, impossible high-resolution can carry out careful examine using in the X ray CT as conventional diagnostic device, nuclear magnetic resonance etc.
It is disconnected.Thus, it applies flexibly special Worth Expecting in the diagnosis and treatment of the trickle focus at medical scene, and except medical
Beyond endoscope apparatus, it can also be applied to industrial OCT diagnostic devices.
Symbol description
1 fixes optical fiber
2 rotation optical fibers
The light path converting mechanism of 3,3a, 3b, 103a, 103b first
4 optical fiber fixtures
5 shields
6 probes (pipe)
7,107,207 motor windings
8,108a, 108b, 208a, 208b motor casing
9a, 9b, 109a, 109b, 218a, 218b clutch shaft bearing
10 hollow rotating shafts
110 first rotary shafts
210 second rotary shafts
11,101,201 rotor magnets
12,112,219 first motor
13,210 second rotary shafts
14,114,214 can vibrating member
14a holes
14b slits
15,115,215 electrostriction elements
16,116,216 pattern electrodes
17,23,123,223 electric wires
18a, 18b, 18a, 18b, 209a, 209b second bearing
19,212 second motor
20,20a, 20b, 120a, 220a, 320 second light path converting mechanisms
21 transmittance sections
21a spheres portion
22,122,222 rotating optical connectors (optical rotary joint)
The pulse generating mechanisms of 24,24a, 24b second
The pulse generating mechanisms of 25,25a, 25b first
26 fiber guides bearings
27 second front side bearings
27a, 27b dynamic pressure produce groove
28 second rear side bearings
28a dynamic pressures produce groove
81 forceps channels
82 guiding probes
83 CCD image pickup parts
84 tops observation portion
85 main bodys
86 first motor drive circuits
87 second motor drive circuits
88 interference of light analysis units
89 computers
90 monitors
124 general plane portions
225 substantially sphere portions
226 first cover bodies
227 second cover bodies
228 229 insulating courses
230 optical fluids
324 reflectings surface
Claims (12)
1. a kind of photoimaging probe, the light for injecting tip side is guided rearward, it is characterised in that on substantially same line
It is configured with：
Fixed optical fiber, is configured to non-rotatable, is built in the probe of generally tubular；
First light path converting mechanism, positioned at the tip side of above-mentioned fixed optical fiber, is driven in rotation, big by the first motor
Cause ray on radial direction；
Optical fiber is rotated, between above-mentioned fixed optical fiber and above-mentioned first light path converting mechanism, passes through rotating optical connector
It is connected, is driven in rotation by the second motor with above-mentioned fixed optical fiber optics；And
Second light path converting mechanism, in the tip side of above-mentioned rotation optical fiber, makes light path tilt small angle relative to pivot
Spend to carry out rotary emission.
2. photoimaging probe according to claim 1, it is characterised in that
The rotary shaft of above-mentioned first motor is hollow shape, is fixed with the first light path converting mechanism, and above-mentioned rotation sidelight
Fibre rotatably runs through the hollow hole of the rotary shaft of first motor,
The rotary shaft of above-mentioned second motor is also hollow shape, is fixed with the hollow hole of the rotary shaft of second motor
Above-mentioned rotation optical fiber simultaneously rotates it.
3. photoimaging probe according to claim 1, it is characterised in that
The rotary shaft of above-mentioned first motor is fixed with above-mentioned first light path converting mechanism, and positioned at than above-mentioned first light path converting
Mechanism close to the position of tip side,
The rotary shaft of above-mentioned second motor is hollow shape, is fixed with the hollow hole of the rotary shaft of second motor
State rotation optical fiber and rotate it.
4. the photoimaging probe according to any one of claims 1 to 3, it is characterised in that
Above-mentioned first motor or above-mentioned second motor at least any one be electronic using the ultrasonic wave of electrostriction element
Machine, by above-mentioned rotary shaft run through the centre bore with polygon prism can vibrating member centre bore, it is above-mentioned can be in vibrating member
Heart hole has the slit portion spread towards periphery, it is above-mentioned can vibrating member outer peripheral face attach it is laminal electroluminescent with electrode
Telescopic element, by successively to above-mentioned electrostriction element apply voltage, make can vibrating member produce whirling vibration, rotary shaft is entered
Row rotation driving.
5. the photoimaging probe according to any one of claims 1 to 3, it is characterised in that
Above-mentioned first light path converting mechanism is rotatable speculum.
6. the photoimaging probe according to any one of claims 1 to 3, it is characterised in that
Above-mentioned first light path converting mechanism is rotatable speculum, and reflecting surface is barrel surface.
7. the photoimaging probe according to any one of claims 1 to 3, it is characterised in that
Above-mentioned second light path converting mechanism is the prism on top with inclined general plane.
8. the photoimaging probe according to any one of claims 1 to 3, it is characterised in that
Above-mentioned second light path converting mechanism is to have the prism of inclined substantially sphere on top or in substantially semi-spherical shape
A part have general plane reflecting surface globe lens.
9. the photoimaging probe according to any one of claims 1 to 3, it is characterised in that
Above-mentioned rotating optical connector have fixed optical fiber and rotate optical fiber the periphery of either one separate it is small between
First cover body of gap covering and the second cover body for separating above-mentioned first cover body of minim gap covering, cover with the first cover body and second
The barrel surface that the above-mentioned minim gap of either one of body is tangent has thread groove, and transparent stream is injected to above-mentioned minim gap
Body.
10. the photoimaging probe according to any one of claims 1 to 3, it is characterised in that
In above-mentioned rotating optical connector, make while slight distance is set in the end face of above-mentioned fixed optical fiber and above-mentioned rotation optical fiber
The two is opposed, to by above-mentioned fixed optical fiber, above-mentioned rotation optical fiber, the bearing of above-mentioned second motor, above-mentioned second electronic
Transparent fluid is injected in the gap that the rotary shaft of machine is constituted.
11. the photoimaging probe according to any one of claims 1 to 3, it is characterised in that
With the first pulse generating mechanisms and the second pulse generating mechanisms, above-mentioned first pulse generating mechanisms are according to the above-mentioned first electricity
The anglec of rotation of motivation, at least rotates the pulse once produced more than once, above-mentioned second pulse generating mechanisms are according to above-mentioned second
The anglec of rotation of motor, at least rotates the pulse once produced more than once,
With controlling organization, the controlling organization passes through from above-mentioned first pulse generating mechanisms and above-mentioned second pulses generation machine
The pulse of structure, to adjust the rotating speed of above-mentioned first motor and above-mentioned second motor,
Relation using the rotating speed N1 of the above-mentioned first motor and rotating speed N2 of above-mentioned second motor is N2=N1-X's [revolutions per second]
Mode is rotated, thus make light from above-mentioned first light path converting mechanism with N1 [revolutions per second] rotating speed to substantially radius side
The releasing angle of light is set to change in the axial direction to releasing, and with X [coming and going/second] speed.
12. photoimaging probe according to claim 11, it is characterised in that
The pulse from above-mentioned first pulse generating mechanisms and above-mentioned second pulse generating mechanisms is received, passes through above-mentioned control machine
Structure, makes above-mentioned first motor and the rotating speed of above-mentioned second motor be rotated with identical rotating speed and be set to holding state,
By the generation of commencing signal, with the rotating speed N1 of the above-mentioned first motor and rotating speed N2 of above-mentioned second motor relation
Mode for N2=N1-X [revolutions per second] makes rotation speed change.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013-167192 | 2013-08-10 | ||
| JP2013167192 | 2013-08-10 | ||
| PCT/JP2013/081805 WO2015022760A1 (en) | 2013-08-10 | 2013-11-26 | Probe for opitcal imaging |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105451627A CN105451627A (en) | 2016-03-30 |
| CN105451627B true CN105451627B (en) | 2017-08-04 |
Family
ID=52468157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380078789.6A Active CN105451627B (en) | 2013-08-10 | 2013-11-26 | Photoimaging is popped one's head in |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9574870B2 (en) |
| EP (1) | EP3031381B1 (en) |
| JP (1) | JP5961891B2 (en) |
| CN (1) | CN105451627B (en) |
| WO (1) | WO2015022760A1 (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10537226B2 (en) * | 2013-12-23 | 2020-01-21 | California Institute Of Technology | Rotational scanning endoscope |
| JP6232552B2 (en) * | 2014-11-25 | 2017-11-22 | 並木精密宝石株式会社 | Optical inner surface measuring device |
| JP6496897B2 (en) * | 2015-03-31 | 2019-04-10 | アダマンド並木精密宝石株式会社 | Optical imaging probe |
| US11076751B2 (en) | 2015-06-19 | 2021-08-03 | Koninklijke Philips N.V. | Imaging system, optical element, and a catheter or endoscope using the same |
| JP6980267B2 (en) * | 2015-09-17 | 2021-12-15 | アダマンド並木精密宝石株式会社 | Probe for optical imaging |
| WO2017191684A1 (en) * | 2016-05-06 | 2017-11-09 | オリンパス株式会社 | Two-dimensional optical deflector |
| WO2018011981A1 (en) * | 2016-07-15 | 2018-01-18 | 並木精密宝石株式会社 | Optical inner surface measurement device |
| KR101903074B1 (en) * | 2016-08-24 | 2018-10-01 | 울산과학기술원 | Photoacoustic and ultrasonic endoscopy system including a coaxially-configured optical and electromagnetic rotary waveguide assembly and embodiment method thereof |
| CN207666578U (en) * | 2016-09-27 | 2018-07-31 | 广州永士达医疗科技有限责任公司 | A kind of pumpback formula OCT systems |
| US10314491B2 (en) * | 2017-02-11 | 2019-06-11 | The General Hospital Corporation | Optics for apodizing an optical imaging probe beam |
| CN106990539B (en) * | 2017-03-27 | 2023-01-31 | 深圳市三千米光电科技有限公司 | Optical fiber vibration device |
| DE102017208106A1 (en) * | 2017-05-15 | 2018-11-15 | Siemens Aktiengesellschaft | Method and device for at least sections, preferably complete determination of the outer and inner geometry of a component having at least one cavity |
| US11224336B2 (en) * | 2017-11-17 | 2022-01-18 | Canon U.S.A., Inc. | Rotational extender and/or repeater for rotating fiber based optical imaging systems, and methods and storage mediums for use therewith |
| RU184084U1 (en) * | 2017-12-13 | 2018-10-15 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Тамбовский государственный технический университет" (ФГБОУ ВО "ТГТУ") | The device of an endoscopic probe for optical coherence tomography |
| CN108095691A (en) * | 2017-12-18 | 2018-06-01 | 广州永士达医疗科技有限责任公司 | A kind of OCT probe rotating driving device for tube chamber road |
| CN108338779A (en) * | 2018-03-07 | 2018-07-31 | 汤姆飞思（香港）有限公司 | A kind of OCT probe driving device and OCT detection devices |
| KR20200043206A (en) | 2018-10-17 | 2020-04-27 | 한국전자통신연구원 | Optical probe and optical probe system including the same |
| CN110403562B (en) * | 2019-07-24 | 2021-10-12 | 青岛大学附属医院 | Straight-bar inseparable hard tube endoscope with infinite visual angle |
| CN116075764A (en) * | 2020-08-28 | 2023-05-05 | 富士胶片株式会社 | Endoscope with a lens |
| US11730548B2 (en) | 2020-12-17 | 2023-08-22 | Industrial Technology Research Institute | Optical coherence tomography scanning probe |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1684624A (en) * | 2002-07-25 | 2005-10-19 | 莱特莱图像公司 | Scanning miniature optical probes with optical distortion correction and rotational control |
| CN1780584A (en) * | 2003-04-28 | 2006-05-31 | 德州系统大学董事会 | Catheter imaging probe and method |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5240003A (en) * | 1989-10-16 | 1993-08-31 | Du-Med B.V. | Ultrasonic instrument with a micro motor having stator coils on a flexible circuit board |
| US6615072B1 (en) | 1999-02-04 | 2003-09-02 | Olympus Optical Co., Ltd. | Optical imaging device |
| US6687010B1 (en) * | 1999-09-09 | 2004-02-03 | Olympus Corporation | Rapid depth scanning optical imaging device |
| US7376455B2 (en) | 2003-05-22 | 2008-05-20 | Scimed Life Systems, Inc. | Systems and methods for dynamic optical imaging |
| US20050143664A1 (en) * | 2003-10-09 | 2005-06-30 | Zhongping Chen | Scanning probe using MEMS micromotor for endosocopic imaging |
| US7364543B2 (en) * | 2004-03-23 | 2008-04-29 | California Institute Of Technology | Paired angled rotation scanning probes and methods of use |
| US8106549B2 (en) | 2007-01-31 | 2012-01-31 | Namiki Seimitsu Houseki Kabushiki Kaisha | Motor and endoscope probe equipped with motor |
| JP2008284340A (en) * | 2007-01-31 | 2008-11-27 | Namiki Precision Jewel Co Ltd | Motor and oct endoscope probe with the motor |
| JP4461216B2 (en) | 2007-03-02 | 2010-05-12 | 並木精密宝石株式会社 | Motor and endoscope probe equipped with the motor |
| JP2009077844A (en) * | 2007-09-26 | 2009-04-16 | Fujifilm Corp | Optical scanning probe |
| JP2009201969A (en) | 2008-02-01 | 2009-09-10 | Fujifilm Corp | Oct optical probe and optical tomography imaging apparatus |
| US8764666B2 (en) * | 2008-10-28 | 2014-07-01 | The Regents Of The University Of California | Ultrasound guided optical coherence tomography, photoacoustic probe for biomedical imaging |
| JP2010200820A (en) * | 2009-02-27 | 2010-09-16 | Fujifilm Corp | Optical three-dimensional structure imaging apparatus and optical signal processing method for the same |
| JP5422849B2 (en) * | 2011-07-26 | 2014-02-19 | 並木精密宝石株式会社 | Optical imaging probe |
| US8861900B2 (en) * | 2012-02-23 | 2014-10-14 | Corning Incorporated | Probe optical assemblies and probes for optical coherence tomography |
| US8967885B2 (en) * | 2012-02-23 | 2015-03-03 | Corning Incorporated | Stub lens assemblies for use in optical coherence tomography systems |
| US9036966B2 (en) * | 2012-03-28 | 2015-05-19 | Corning Incorporated | Monolithic beam-shaping optical systems and methods for an OCT probe |
| CN103110403B (en) * | 2013-01-14 | 2014-09-17 | 天津大学 | Novel optical probe |
| US20150355413A1 (en) * | 2014-06-04 | 2015-12-10 | Corning Incorporated | Integrated torque jacket systems and methods for oct |
-
2013
- 2013-11-26 JP JP2015531718A patent/JP5961891B2/en active Active
- 2013-11-26 WO PCT/JP2013/081805 patent/WO2015022760A1/en active Application Filing
- 2013-11-26 EP EP13891516.0A patent/EP3031381B1/en not_active Not-in-force
- 2013-11-26 CN CN201380078789.6A patent/CN105451627B/en active Active
-
2016
- 2016-02-08 US US15/018,322 patent/US9574870B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1684624A (en) * | 2002-07-25 | 2005-10-19 | 莱特莱图像公司 | Scanning miniature optical probes with optical distortion correction and rotational control |
| CN1780584A (en) * | 2003-04-28 | 2006-05-31 | 德州系统大学董事会 | Catheter imaging probe and method |
Also Published As
| Publication number | Publication date |
|---|---|
| US20160153765A1 (en) | 2016-06-02 |
| EP3031381A4 (en) | 2017-04-12 |
| JPWO2015022760A1 (en) | 2017-03-02 |
| WO2015022760A1 (en) | 2015-02-19 |
| US9574870B2 (en) | 2017-02-21 |
| CN105451627A (en) | 2016-03-30 |
| EP3031381A1 (en) | 2016-06-15 |
| EP3031381B1 (en) | 2017-11-15 |
| JP5961891B2 (en) | 2016-08-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105451627B (en) | Photoimaging is popped one's head in | |
| CN105722445B (en) | Optical imagery detector | |
| US20140221747A1 (en) | Apparatus, systems and methods which include and/or utilize flexible forward scanning catheter | |
| US20050143664A1 (en) | Scanning probe using MEMS micromotor for endosocopic imaging | |
| JP5601321B2 (en) | Optical coupling device and optical tomography apparatus | |
| US8911357B2 (en) | Optical structure observation apparatus and structure information processing method of the same | |
| CN1586402A (en) | Endoscopic optical tomographic imaging scanning probe device based on micro motor | |
| US20120212595A1 (en) | Optical Endoluminal Far-Field Microscopic Imaging Catheter | |
| CN102058381B (en) | Three-dimensional electronic bronchoscope system and use method thereof | |
| WO2008111970A1 (en) | Side viewing optical fiber endoscope | |
| CN102090881B (en) | Three-dimensional (3D) hard electronic anus and intestines endoscope system | |
| JP2015008995A (en) | Optical imaging probe | |
| CN105476592A (en) | Separable endoscope | |
| JP6281059B2 (en) | Optical imaging probe | |
| JP6439098B2 (en) | Optical imaging probe | |
| CN102058387B (en) | Novel three-dimensional electronic choledochoscope system and use method thereof | |
| CN102058384A (en) | Novel three-dimensional electronic cystoscope system and use method thereof | |
| CN102090880B (en) | Three-dimensional hard electronic arthroscope system | |
| CN102090879B (en) | Three-dimensional hard electronic cholecystoscope system | |
| CN102058382B (en) | Three-dimensional electronic gastroscope system and using method thereof | |
| JP3179184B2 (en) | Ultrasound probe with observation function | |
| CN102090878B (en) | Three-dimensional hard electronic cystoscope system and using method thereof | |
| JP6980267B2 (en) | Probe for optical imaging | |
| JP2015100569A (en) | Probe for optical imaging | |
| WO2019140152A1 (en) | System and apparatus for forward-view imaging |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: Tokyo, Japan, Japan Patentee after: Andaman nanoscale precision gem Co., Ltd. Address before: Tokyo, Japan, Japan Patentee before: Namiki Precision Jewel Co., Ltd. |
|
| CP01 | Change in the name or title of a patent holder |