CN105433389A - Blood sugar lowering liquid composition based on okra fermentation juice, and preparation method thereof - Google Patents
Blood sugar lowering liquid composition based on okra fermentation juice, and preparation method thereof Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Engineering & Computer Science (AREA)
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Abstract
The invention provides a blood sugar lowering liquid composition based on an okra fermentation juice, and a preparation method thereof. The liquid composition comprises 20-99.94% (by volume) of the okra fermentation juice, 0.05-1.5% (by percent weight in volume) of a flavoring, 0.01-0.1% (by percent weight in volume) of an antiseptic, and the balance of water. The composition has unique mouthfeel, is clarified and transparent, and has the health and treatment efficacy of blood sugar lowering.
Description
Technical field
The invention belongs to Medicines and Health Product technical field, particularly one is based on the hypoglycemic fluid composition of okra fermented juice and preparation method.
Background technology
Okra (HibisusessulentusL.) has another name called swordweed, Abelmoschus esculentus, hair eggplant, for a kind of Malvaceae (Abelmoschus) Abelmoschus (Malvaceae), belong to annual herb plant, originate in Africa, also there are wild species in China.Extensively cultivate in torrid areas such as Europe Africa Middle East, India and Southeast Asia at present.The people institute heat that become okra pursues high a grade nutritive health-care vegetable, the fashionable whole world.American is called " plant gold gold autumn certain herbaceous plants with big flowers ", is hypoglycemic good medicine, and its edible portion is fruit pod, divides again green and red two kinds, its tender and crisp succulence, and lubricious oiliness, fragrance is unique, deeply favors by the common people.Record according to the ancient books such as Compendium of Material Medica, the root, stem, flower, seed etc. of gumbo all can be used as medicine, and its nature and flavor are sweet, cold, sliding, enter the heart, lung, kidney, stomach, liver and bladder, can control insufficiency of the spleen weak, the dry constipation of intestines and illness such as evil sore, carbuncle furuncle etc.Gumbo is the new vegetables of one occurred in recent years in the international market, and health value is very high.Often ediblely to help digest, to reduce blood fat, strengthen muscle power and the endurance of people.There are protection stomach, liver, skin and mucous membrane, strengthen the effect of skin elasticity; And it is all effective in cure to diseases such as gastritis, gastric ulcer, livers.Also has the effect strengthening physical endurance and strong kidney qi-restoratives, be described as " plant vigour " and become popular situation of selling well vegetables in Japan, Taiwan, Hong Kong and western countries, the many countries in Africa become sportsman edible first choice of vegetables, the especially health food of the elderly.Gumbo is mainly containing pectin, and glycopeptide, the nutriments such as protein, owing to wherein the absorption of carbohydrate can reach antidotal effect in control volume containing peptidoglycan is often edible.In addition, prior art Chinese patent CN101991620A discloses the medicament and application thereof prepared with Abelmoschus Esculentus Linn extract, is applied in the medicine for the treatment of or prevention impotence, premature ejaculation, stomach trouble, heart disease, apoplexy, skeleton bulking and Alzheimer etc.
The main component of relevant bibliographical information okra has amino acid and protein, trace element, polysaccharide, flavone compound, containing a kind of stickiness polysaccharide material be made up of pectin, cow's milk glycan and gum arabic etc. in the tender pod of gumbo.In addition, it is also containing abundant vitamin A, B, C etc.Its pharmacological action has antifatigue effect, improves immunity of organisms, reduces injury of lungs, antitumaous effect; glycoprotein containing a kind of stickiness in young fruit; often ediblely to help digest, stomach invigorating, whole intestines, protection stomach, liver and skin, mucous membrane effect, all effective in cure to diseases such as gastritis, gastric ulcer, livers.The sweet cunning of okra taste, there is invigorating spleen and reinforcing stomach, moisturize effect of sharp intestines, the diseases such as insufficiency of the spleen weak, the dry constipation of intestines can be controlled.(" progress of okra " traditional Chinese medicine academic periodical .2005.23 (10)).Chinese invention patent CN201210276745.1 discloses a kind of blood sugar reducing food containing okra and preparation method thereof.Be that raw material is made by the okras of 30 ~ 60 parts, the balsam pear of 15 ~ 45 parts and the Chinese yam of 15 ~ 45 parts.This invention blood-sugar reducing tea of " okra blood-sugar reducing tea and production technology thereof " (Chinese invention patent CN201410651419.3) is combined by a certain percentage and is ground into pulvis by tender okra fruit, potentilla discolor, corn stigma, leaf of Herba Apii graveolentis through high temperature dehydration, is mainly used in adjuvant therapy of diabetes, diabetic nephropathy syndrome." a kind of compound okra hypoglycemic freeze-dried powder and preparation method " (Chinese invention patent CN201510209787.7) this invention freeze-dried powder makes dry powder with okra, coix seed, white fungus, onion, STEVIA REBAUDIANA for raw material adopts vacuum freeze drying and breaking-wall cell ultrastructurepower technology to pulverize, and is mainly used in diabetes supplemental treatment.All directly combine with okra itself about assistant hypoglycemic in above-mentioned patent, do not relate to the effect of okra fermented juice for adjuvant therapy of diabetes.
Summary of the invention
In view of the technical problem that prior art exists, an object of the present invention is to provide a kind of based on the hypoglycemic fluid composition of okra fermented juice.
The present invention is realized by following approach:
A kind of based on the hypoglycemic fluid composition of okra fermented juice, the component of described fluid composition and proportioning are:
Okra fermented juice (percent by volume) 20%-99.94%;
Flavouring (percent weight in volume) 0.05%-1.5%;
Anticorrisive agent (percent weight in volume) 0.01%-0.1%;
Surplus is water.
Described flavouring is selected from one in glycine, alanine, peppermint oil, orange-seed oil or its mixture.
Described anticorrisive agent is selected from one in benzoic acid, potassium sorbate, ethyl-para-hydroxybenzoate or its mixture.
Obtain by the okra of fermentation the fluid composition that fermented juice goes out with suitable auxiliaries, its mouthfeel uniqueness, clear, can blood sugar be reduced, have and keep healthy and therapeutic efficiency.
The pH value of described fluid composition is 3.0 – 5.5, soluble solid content is 2.5%-12.0%.Can ensure that solution mass is homogeneous, solid content crosses that I haven't seen you for ages affects effect, and the too much solution uniformity of solid content reduces.
Further preferred described composition pH value is 3.0 – 4.5, and soluble solids content is 5.0% – 9.0%.Effect of material can be ensured, the homogeneity of solution mass can be ensured again.
Another object of the present invention is to provide described a kind of based on the application of the hypoglycemic fluid composition of okra fermented juice at preparation hypoglycemic health products, food or medicine.
Or okra fermented juice is in the application of preparation hypoglycemic health products, food or medicine.Preferred described okra fermented juice preparation method is: the okra of maturation is placed in 23-28 DEG C of closed container and ferments 2 – 4 months, get okra fermented juice, sterilize, filter to get filtrate.
Preferably add honey to ferment, the weight ratio of honey and okra is honey: okra: water=1:3:10.
The formulation of described health products, food or medicine is preferably oral liquid.
Described soluble solid refers to all general names being dissolved in the compound of water in liquid or fluid.
Another object of the present invention is to provide a kind of method preparing the fluid composition of described okra fermented juice, comprise step:
(1) okra of maturation is placed in 23-28 DEG C of closed container to ferment 2 – 4 months, gets okra fermented juice, bus sterilization, filter to get filtrate;
(2) with adding in filtrate after water-soluble solution flavouring and anticorrisive agent;
(3) amount of preparation is settled to water.
Wherein, be preferably the nylon membrane class filter media of 10-100 μm by step (1) fermented juice filtering technique, or retain aperture 4 – 400,000 molecular weight polymeric hollow cellulose membrane with film and carry out ultrafiltration.
Filtrate after preferably step (3) being prepared is that the miillpore filter of 0.22 μ m – 0.8 μm or micropore filter element carry out micro-filtration by aperture, and preferred microporous filter membrane or micropore filter element aperture the best are 0.22 μm.
The present invention is with the impact of okra fermented juice on blood glucose in diabetic mice level caused by alloxan.This experiment show okra fermentation Normal juice dilute 10 times after administration 15 days, to diabetic mice caused by alloxan, there is obvious blood sugar reducing function.
The present invention has good effect relative to prior art:
The present invention has obvious blood sugar reducing function with okra fermented juice, the present invention is decompose out by okra active principle by spontaneous fermentation and be degraded into small-molecule substance with okra fermented juice, especially ferment gained polysaccharide and trace element etc. material there is obvious hypoglycemic activity, compare with common extract with okra itself, the molecular weight of material of fermentation gained is less, the active ingredient obtained is more, more easily absorbs and applies.
The okra fermented juice fluid composition color and luster produced by carrying out spontaneous fermentation under certain condition is faint yellow to yellow, there is the soft clear of refrigerant tart flavour, organoleptic feature without bitter taste, unique flavor, maintain natural nutrient component and the active material of okra, especially have and fall hypoglycemic health-care efficacy.
The present invention proposes the quality standard of concrete suitability for industrialized production and production technology and product according to different auxiliary material adding proportion and kind; Again, the present invention is as health products, and its product form can be oral liquid, fruit drink or other fluid products, lozenge, cavity disintegrated tablet or other tablet.Therefore, it is domestic okra deep development, provides processing and utilization okra technological approaches, expands application, improve the economic worth of okra.
Detailed description of the invention
Below by instantiation, realization means of the present invention is described, but is not limited only to this.
(1) product of the present invention and preparation method
Embodiment 1
Be cut into fragment after being cleaned by the okra of maturation, add honey and put into airtight container and carry out fermentation 4 months at 23 DEG C-28 DEG C, middlely to be bled off by the gas of generation, soluble solid content reaches 9.0%, and pH value reaches 3.5; Get okra fermented juice 85 DEG C sterilization 20 seconds.Solution temperature is cooled to less than 26 DEG C to filter through row, and filtered fluid to ferment Normal juice as okra.
Preparation okra oral liquid 100 milliliters: get okra Normal juice 70 milliliters, wherein soluble solid content is 5%, pH value is 4.0, by glycine 1.0 grams, peppermint oil 0.1 milliliter (peppermint oil proportion is 1g/ml), Sodium Benzoate 0.05 gram, with after appropriate water-soluble solution mixing, adds in the Normal juice after okra dilution, with water constant volume to amount of preparation, record into oral liquid.
Embodiment 2
Be cut into fragment after being cleaned by the okra of maturation, add honey and put into airtight container and carry out fermentation 2 months at 23 DEG C-28 DEG C, middlely to be bled off by the gas of generation, soluble solid content reaches 7.0%, and pH value reaches 4.0; Get okra fermented juice 85 DEG C sterilization 15 seconds.Solution temperature is cooled to less than 26 DEG C to filter, and filtered fluid to ferment Normal juice as okra.
Preparation okra oral liquid 100 milliliters: get the rear Normal juice 20 milliliters of okra dilution, wherein soluble solid content is 9.0%, pH value is 3.0, by glycine or alanine 1.0 grams, peppermint oil 0.5 milliliter (peppermint oil proportion is 1g/ml), Sodium Benzoate 0.05 gram is with after appropriate water-soluble solution mixing, add in the Normal juice after okra dilution, filter with the 15 μm of nylon membranes in aperture or carry out ultrafiltration get filtrate with retaining aperture 100,000 hollow cellulose film, with water constant volume to amount of preparation, again the filtrate of preparation is carried out filtration sterilization with the miillpore filter of 0.45 μm or filter core, record into oral liquid.
Embodiment 3
Be cut into fragment after being cleaned by the okra of maturation, add honey and put into airtight container and carry out fermentation 3 months at 23 DEG C-28 DEG C, middlely to be bled off by the gas of generation, soluble solid content reaches 7.0%, and pH value reaches 3.5; Get okra fermented juice 70 DEG C sterilization 20 seconds.Solution temperature is cooled to less than 26 DEG C to filter, and filtered fluid to ferment Normal juice as okra.
Preparation okra oral liquid 100 milliliters: get the rear Normal juice 20 milliliters of okra dilution, wherein soluble solid content is 9.0%, pH value is 3.0, by glycine or alanine 0.5 gram, peppermint oil 0.5 milliliter (peppermint oil proportion is 1g/ml), Sodium Benzoate 0.05 gram is with after appropriate water-soluble solution mixing, add in the Normal juice after okra dilution, filter with the 60 μm of nylon membranes in aperture or carry out ultrafiltration get filtrate with retaining aperture 400,000 hollow cellulose film, with water constant volume to amount of preparation, record into oral liquid.
Embodiment 4
Be cut into fragment after being cleaned by the okra of maturation, add honey and put into airtight container and carry out fermentation 3 months at 23 DEG C-28 DEG C, middlely to be bled off by the gas of generation, soluble solid content reaches 8.0%, and pH value reaches 3.5; Get okra fermented juice 70 DEG C sterilization 30 seconds.Solution temperature is cooled to less than 26 DEG C to filter, and filtered fluid to ferment Normal juice as okra.
Preparation okra oral liquid 100 milliliters: get the rear Normal juice 20 milliliters of okra dilution, wherein soluble solid content is 9.0%, pH value is 3.0, by glycine or alanine 1.5 grams, peppermint oil 0.5 milliliter (peppermint oil proportion is 1g/ml), Sodium Benzoate 0.05 gram is with after appropriate water-soluble solution mixing, add in the Normal juice after okra dilution, filter with the 15 μm of nylon membranes in aperture or carry out ultrafiltration get filtrate with retaining aperture 100,000 hollow cellulose film, with water constant volume to amount of preparation, again the filtrate of preparation is carried out filtration sterilization with the miillpore filter of 0.22 μm or filter core, record into oral liquid.
Embodiment 5
Be cut into fragment after being cleaned by the okra of maturation, add honey and put into airtight container and carry out fermentation 4 months at 23 DEG C-28 DEG C, middlely to be bled off by the gas of generation, soluble solid content reaches 9.0%, and pH value reaches 3.5; Get okra fermented juice 85 DEG C sterilization 30 seconds.Solution temperature is cooled to less than 26 DEG C to filter, and filtered fluid to ferment Normal juice as okra.
Preparation okra oral liquid 100 milliliters: get the rear Normal juice 90 milliliters of okra dilution, wherein soluble solid content is 9.0%, pH value is 3.0, by glycine or alanine 1.5 grams, Sodium Benzoate 0.1 gram is with after appropriate water-soluble solution mixing, add in the Normal juice after okra dilution, filter with the 15 μm of nylon membranes in aperture or carry out ultrafiltration get filtrate with retaining aperture 200,000 hollow cellulose film, with water constant volume to amount of preparation, again the filtrate of preparation is carried out filtration sterilization with the miillpore filter of 0.22 μm or filter core, record into oral liquid.
(2) okra fermented juice is on the impact of blood glucose in diabetic mice level caused by alloxan
Embodiment 6
Select the male mouse of kunming of body weight 18-22g, water 18h is can't help in fasting, diabetes model set up by tail vein injection 100mg/kg alloxan, after 5 days, the mouse of fasting 12h is cut tail and gets blood, measure fasting blood-glucose, more than blood sugar 11.0mmol/L thinks that diabetes model is successful, diabetic mice is divided into 6 groups, namely blank group, model group, positive drug group (75mg/kg DB2), three dosage okra fermented juice administration groups, okra fermented juice 10ml/kg, 20ml/kg, 40ml/kg tri-dosage groups, more excellent hypoglycemic effect is had relative to Abelmoschus Esculentus Linn extract, blank dosage group and model dosage group gavage every day give pure water, positive drug group gavage every day gives 75mg/kg DB2, every day gavage once, okra fermented juice gavage every day twice, 15 days (as table 1) of continuous gavage
Table 1 alloxan causes the impact test of blood glucose in diabetic mice level
Experimental result shows: model control group, positive controls, okra fermented juice three dosage groups mouse blood sugar after alloxan injection raises, the success of explanation diabetes model, okra three dosage gastric infusions are after 15 days, have relative to model group and significantly fall hypoglycemic effect, though not as good as positive control drug, but possess clear superiority as functional health care product and food, and from natural materials, toxic and side effect aspect has a clear superiority in.
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from Spirit Essence of the present invention and principle, substitute, combine, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.
Claims (10)
1. based on the hypoglycemic fluid composition of okra fermented juice, it is characterized in that, the component of described fluid composition and proportioning are:
Okra fermented juice (percent by volume) 20%-99.94%;
Flavouring (percent weight in volume) 0.05%-1.5%;
Anticorrisive agent (percent weight in volume) 0.01%-0.1%;
Surplus is water.
2. fluid composition according to claim 1, is characterized in that, described flavouring is selected from one in glycine, alanine, peppermint oil, orange-seed oil or its mixture.
3. the fluid composition according to claims 1, is characterized in that, described anticorrisive agent is selected from one in benzoic acid, potassium sorbate, ethyl-para-hydroxybenzoate or its mixture.
4. the fluid composition according to the arbitrary claim of claims 1 to 3, is characterized in that the pH value of described fluid composition is 3.0 – 5.5, soluble solid content is 2.5%-12.0%.
5., according to the fluid composition that claims 4 are stated, it is characterized in that described composition pH value is 3.0 – 4.5, soluble solids content is 5.0% – 9.0%.
6. the arbitrary claim of claim 1 – 5 is a kind of based on the application of the hypoglycemic fluid composition of okra fermented juice at preparation hypoglycemic health products, food or medicine.
7. prepare a method for the fluid composition of okra fermented juice described in the arbitrary claim of claim 1 – 6, comprise step:
(1) okra of maturation is placed in 23-28 DEG C of closed container to ferment 2 – 4 months, gets okra fermented juice, bus sterilization, filter to get filtrate;
(2) with adding in filtrate after water-soluble solution flavouring and anticorrisive agent;
(3) amount of preparation is settled to water.
8. prepare fluid composition method according to claim 7, it is characterized in that being the nylon membrane class filter media of 10-100 μm by step (1) fermented juice filtering technique, or retain aperture 4 – 400,000 molecular weight polymeric hollow cellulose membrane with film and carry out ultrafiltration.
9. prepare fluid composition method according to claim 7, it is characterized in that the filtrate after step (3) being prepared is that the miillpore filter of 0.22 μ m – 0.8 μm or micropore filter element carry out micro-filtration by aperture, preferred microporous filter membrane or micropore filter element aperture the best are 0.22 μm.
10. okra fermented juice is in the application of preparation hypoglycemic health products, food or medicine.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101791139A (en) * | 2010-02-01 | 2010-08-04 | 阚欢 | Blood sugar level or blood pressure regulating liquid composite based on Noni fermented juice and preparation method thereof |
| CN104223271A (en) * | 2014-10-13 | 2014-12-24 | 江苏省农业科学院 | Okra lactobacillus fermented beverage |
| CN104305429A (en) * | 2014-11-18 | 2015-01-28 | 黄秋函 | Fermentation type okra tea drink |
-
2015
- 2015-12-15 CN CN201510936881.2A patent/CN105433389A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101791139A (en) * | 2010-02-01 | 2010-08-04 | 阚欢 | Blood sugar level or blood pressure regulating liquid composite based on Noni fermented juice and preparation method thereof |
| CN104223271A (en) * | 2014-10-13 | 2014-12-24 | 江苏省农业科学院 | Okra lactobacillus fermented beverage |
| CN104305429A (en) * | 2014-11-18 | 2015-01-28 | 黄秋函 | Fermentation type okra tea drink |
Non-Patent Citations (1)
| Title |
|---|
| 乐活编辑部: "《发酵酵素圣经》", 31 January 2015 * |
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