CN105412774A - Traditional Chinese medicine composition for treating ulcerative colitis - Google Patents

Traditional Chinese medicine composition for treating ulcerative colitis Download PDF

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Publication number
CN105412774A
CN105412774A CN201511012818.6A CN201511012818A CN105412774A CN 105412774 A CN105412774 A CN 105412774A CN 201511012818 A CN201511012818 A CN 201511012818A CN 105412774 A CN105412774 A CN 105412774A
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chinese medicine
traditional chinese
medicine composition
ulcerative colitis
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CN201511012818.6A
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Inventor
王璐
许璟
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Qingdao Changanda Pharmaceutical Co Ltd
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Qingdao Changanda Pharmaceutical Co Ltd
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Priority to CN201511012818.6A priority Critical patent/CN105412774A/en
Publication of CN105412774A publication Critical patent/CN105412774A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9062Alpinia, e.g. red ginger or galangal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition for treating ulcerative colitis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine composition raw materials, by weight, 41-50 parts of knoxia root, 32-46 parts of pokeberry root, 30-39 parts of kaempferia galamga, 25-34 parts of alpinia katsumadai, 20-26 parts of rhododendron mariae, 15-24 parts of deer-horn glue and 10-16 parts of bighead atractylodes rhizome. The provided traditional Chinese medicine composition employs a plurality of traditional Chinese medicines for cooperation, has functions of invigorating circulation of blood to dispel stasis, strengthening spleen, benefiting qi, cooling blood, stopping bleeding, warming middle-jiao, stopping vomit, promoting qi circulation to relieve pain. Compared with the prior art, the provided traditional Chinese medicine composition can treat ulcerative colitis fundamentally, has definite therapeutic effects, is low in cost and has no toxic or side effects.

Description

A kind of Chinese medicine composition for the treatment of ulcerative colitis
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of ulcerative colitis.
Background technology
Ulcerative colitis is a kind of colon chronic nonspecific inflammatory diseases, belongs to modern medicine refractory disease.Its symptom main manifestations is early stage bloody diarrhea, and discharge the feces containing blood, pus and mucus, with paroxysmal spastic colon pain, tenesmus, can alleviate after defecation.Other symptoms have stomachache successively, lose weight, vomiting etc.Symptom the lighter, suffers from diarrhoea less than 5 times every day, and severe one more than 5 times is watery diarrhea or hemafecia, suffers from abdominal pain heavier, and with heating paresthesia; Clinically adopt aminosalicylic acids and the solid acids Drug therapy of cortex class at present more, but rebound after there is drug withdrawal, the shortcoming such as curative effect is unstable, long-term prescription side effect is larger; Operative treatment, excises whole colon exactly, but due to operation complication more.
Summary of the invention
Technical problem to be solved by this invention is: provide a kind of Chinese medicine composition for the treatment of ulcerative colitis.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of Chinese medicine composition for the treatment of ulcerative colitis provided by the invention, is made up of the traditional Chinese medicine composite of following weight portion: Radix Knoxiae 41-50 part, Radix Phytolaccae 32-46 part, Rhizoma Kaempferiae 30-39 part, Semen Alpiniae Katsumadai 25-34 part, Folium et Cacumen Rhododendri Mariae 20-26 part, Colla cornus cervi 15-24 part, Rhizoma Atractylodis Macrocephalae 10-16 part.
Preferably, Chinese medicine composition provided by the invention is made up of the traditional Chinese medicine composite of following weight portion: Radix Knoxiae 45 parts, Radix Phytolaccae 36 parts, Rhizoma Kaempferiae 33 parts, Semen Alpiniae Katsumadai 29 parts, Folium et Cacumen Rhododendri Mariae 22 parts, Colla cornus cervi 18 parts, the Rhizoma Atractylodis Macrocephalae 12 parts.
Usage and dosage: by above-mentioned Chinese medicine composition warm water soaking after 10 minutes, simmers in water after boiling with high heat 30 minutes again, taking liquid 150 milliliters, then adds water and two to decoct, and filters, take after twice medicinal liquid mixing at twice.Twice daily, one after each meal.
The course for the treatment of: 15 days be a course for the treatment of, the 2-5 course for the treatment of need be taken.
Beneficial effect of the present invention:
Beneficial effect of the present invention: Chinese medicine composition provided by the invention coordinates by adopting kinds of traditional Chinese medicines compositions, there is effect of blood circulation promoting and blood stasis dispelling, invigorating the spleen and replenishing QI, cooling blood for hemostasis, warming middle-JIAO to arrest vomiting, promoting the circulation of QI to relieve pain, compared with prior art, the present invention fundamentally can treat ulcerative colitis, determined curative effect, with low cost, and have no side effect.
Detailed description of the invention
Embodiment 1
A kind of Chinese medicine composition for the treatment of ulcerative colitis that the present embodiment provides, is made up of the traditional Chinese medicine composite of following weight portion: Radix Knoxiae 45 parts, Radix Phytolaccae 36 parts, Rhizoma Kaempferiae 33 parts, Semen Alpiniae Katsumadai 29 parts, Folium et Cacumen Rhododendri Mariae 22 parts, Colla cornus cervi 18 parts, the Rhizoma Atractylodis Macrocephalae 12 parts.
Clinical report is as follows: 1, in the routine patient of physical data 100, and in age 22-71 year, the course of disease is many at 2 months to 4 years, 41 years old mean age.2, diagnostic criteria State Administration of Traditional Chinese Medicine " the Chinese medical disease Standardization of diagnosis and curative effect " issued: ulcerative colitis symptom: primary symptom: (1) constipation or a small amount of pus and blood of excrement band; (2) difficult defecation; (3) afternoon low grade fever; (4) insomnia night sweat; (5) the few tongue of red tongue; (6) thready and rapid pulse.Secondary disease: (1) susceptible to lose temper due to restlessness; (2) have a dizzy spell; (3) have a dull ache in abdomen; (4) spiritlessness and weakness; (5) oliguria with reddish urine; (6) intestinal mucosa is matt, and blood vessel exposes; ; (7) intestinal mucosa is coarse in graininess.Possesses primary symptom 2, secondary disease 2; Or primary symptom the 1st, secondary disease 3.3, usage and dosage:
By above-mentioned Chinese medicine composition warm water soaking after 10 minutes, simmer in water again after boiling with high heat 30 minutes, taking liquid 150 milliliters, then add water and two to decoct, filter after twice medicinal liquid mixing, take at twice.Twice daily, one after each meal.
The course for the treatment of: 15 days be a course for the treatment of, the 2-5 course for the treatment of need be taken.
4, therapeutic outcome: 4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ": recovery from illness: clinical cardinal symptom disappears, secondary disease disappears or substantially disappears, tongue, arteries and veins recover normal substantially, and colonoscopy shows that intestinal mucosa pathological changes is recovered normal or leaves over cicatrix, and stool routine examination microscopy 3 is subnormal; Effective: clinical cardinal symptom disappears substantially, secondary disease is improved degree and is reached more than secondary, and tongue, arteries and veins recover normal substantially, and colonoscopy mucosa infection recovery extent reaches more than secondary, and stool routine examination checks that the every high power field of red white corpuscle number is below 3; Take a turn for the better: clinical cardinal symptom improvement reaches more than one-level, and colonoscopy mucosa infection recovery extent reaches more than one-level, and stool routine examination checks that the every high power field of red white corpuscle number is at about 5; Invalid: before and after treatment, symptom and colonoscopy are without change.4.2 results: in 100 routine patients, recovery from illness 88 example, effective 6 examples, take a turn for the better 3 examples, and invalid 3 examples, total effective rate is 97%.
Model case:
1, hair, man, 60 years old, suffer from more than two years of ulcerative colitis, often with suffering from abdominal pain, have blood in stool, lose weight, tenesmus, vomiting etc. General Symptoms, through multi-treatment less effective, after take Chinese medicine composition of the present invention, after 2 courses for the treatment of, symptom obviously alleviates, after continue to take 2 courses for the treatment of with consolidate curative effect, cure.
2, the Qin, female, 43 years old, suffers from ulcerative colitis half a year, recurrent exerbation stomachache, diarrhoea, bloody purulent stool, and take Chinese medicine composition of the present invention, after taking 1 course for the treatment of, symptom obviously alleviates, and rear continuation takes 2 courses for the treatment of with consolidate curative effect, cures.

Claims (2)

1. treat a Chinese medicine composition for ulcerative colitis, it is characterized in that, be made up of the traditional Chinese medicine composite of following weight portion: Radix Knoxiae 41-50 part, Radix Phytolaccae 32-46 part, Rhizoma Kaempferiae 30-39 part, Semen Alpiniae Katsumadai 25-34 part, Folium et Cacumen Rhododendri Mariae 20-26 part, Colla cornus cervi 15-24 part, Rhizoma Atractylodis Macrocephalae 10-16 part.
2. Chinese medicine composition according to claim 1, is characterized in that, is made up of the traditional Chinese medicine composite of following weight portion: Radix Knoxiae 45 parts, Radix Phytolaccae 36 parts, Rhizoma Kaempferiae 33 parts, Semen Alpiniae Katsumadai 29 parts, Folium et Cacumen Rhododendri Mariae 22 parts, Colla cornus cervi 18 parts, the Rhizoma Atractylodis Macrocephalae 12 parts.
CN201511012818.6A 2015-12-31 2015-12-31 Traditional Chinese medicine composition for treating ulcerative colitis Pending CN105412774A (en)

Priority Applications (1)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168922A (en) * 2015-09-18 2015-12-23 马鞍山德宏堂生物科技有限公司 Traditional Chinese medicine decoction for treating ulcerative colitis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168922A (en) * 2015-09-18 2015-12-23 马鞍山德宏堂生物科技有限公司 Traditional Chinese medicine decoction for treating ulcerative colitis

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Application publication date: 20160323