CN105412762A - Traditional Chinese medicine for treating gastrointestinal dysfunction in patients with ICU cerebral apoplexy and preparation method of traditional Chinese medicine - Google Patents
Traditional Chinese medicine for treating gastrointestinal dysfunction in patients with ICU cerebral apoplexy and preparation method of traditional Chinese medicine Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention relates to a traditional Chinese medicine for treating gastrointestinal dysfunction in patients with ICU cerebral apoplexy and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine consists of the following raw materials in parts by weight: 2-6 parts of eucommia bark, 1-5 parts of ground beetle, 2-10 parts of rhizoma galangae, 1-5 parts of dung beetle, 2-10 parts of cortex moutan, 3-5 parts of peach kernel, 6-8 parts of roasted perilla seed, 5-8 parts of folium artemisiae argyi, 3-10 parts of flos carthami, 2-5 parts of cassia twig, 3-6 parts of rhizoma sparganii, 5-8 parts of flos chrysanthemi, 3-6 parts of radix aconiti carmichaeli and 1-5 parts of radix salviae miltiorrhizae. The traditional Chinese medicine, when applied on umbilicus, can effectively promote the recovery of gastrointestinal dysfunction in patients with cerebral apoplexy and can shorten a time of recovering the gastrointestinal dysfunction.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind ofly treat Chinese medicine of ICU patients with cerebral apoplexy gastrointestinal dysfunction and preparation method thereof.
Background technology
Under normal circumstances, human body intestinal canal mucosa can stop in intestinal endotoxin, antibacterial and harmful substance intrusive body effectively.The multiple stress state such as operation, infection, inflammatory bowel, severe trauma, shock or critical illness all can cause gut muco-membranous barrier to damage, intestinal bacterium displacement causes intestinal pathogenic infection, cause and increase the weight of systemic inflammatory response syndrome (SIRS), and the generation of SIRS has more increased the weight of intestinal injury, form vicious cycle, finally cause multiple organ dysfunction syndrome (MODS) and multiple organ dysfunction syndrome (MOF).
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine for the treatment of ICU patients with cerebral apoplexy gastrointestinal dysfunction, curative effect is reliable.
The present invention is realized by following technical scheme:
Treat a Chinese medicine for ICU patients with cerebral apoplexy gastrointestinal dysfunction, be made up of the raw material of following weight portion:
Cortex Eucommiae 2-6 part, Eupolyphaga Seu Steleophaga 1-5 part, Rhizoma Alpiniae Officinarum 2-10 part, Catharsii molossi 1-5 part, Cortex Moutan 2-10 part, Semen Persicae 3-5 part, stir-baked FRUCTUS PERILLAE 6-8 part, Folium Artemisiae Argyi 5-8 part, Flos Carthami 3-10 part, Ramulus Cinnamomi 2-5 part, Rhizoma Sparganii 3-6 part, Flos Chrysanthemi 5-8 part, Radix Aconiti Lateralis Preparata 3-6 part, Radix Salviae Miltiorrhizae 1-5 part.
Preferably, be made up of the raw material of following weight portion:
The Cortex Eucommiae 6 parts, Eupolyphaga Seu Steleophaga 1 part, Rhizoma Alpiniae Officinarum 2 parts, Catharsii molossi 5 parts, Cortex Moutan 2 parts, 5 parts, Semen Persicae, stir-baked FRUCTUS PERILLAE 6 parts, Folium Artemisiae Argyi 8 parts, 3 parts, Flos Carthami, Ramulus Cinnamomi 2 parts, Rhizoma Sparganii 6 parts, Flos Chrysanthemi 5 parts, Radix Aconiti Lateralis Preparata 6 parts, Radix Salviae Miltiorrhizae 5 parts.
Preferably, be made up of the raw material of following weight portion:
The Cortex Eucommiae 2 parts, Eupolyphaga Seu Steleophaga 5 parts, Rhizoma Alpiniae Officinarum 10 parts, Catharsii molossi 1 part, Cortex Moutan 10 parts, 3 parts, Semen Persicae, stir-baked FRUCTUS PERILLAE 8 parts, Folium Artemisiae Argyi 5 parts, 10 parts, Flos Carthami, Ramulus Cinnamomi 5 parts, Rhizoma Sparganii 3 parts, Flos Chrysanthemi 8 parts, Radix Aconiti Lateralis Preparata 3 parts, Radix Salviae Miltiorrhizae 1 part.
The present invention also provides the method for the Chinese medicine preparing above-mentioned treatment ICU patients with cerebral apoplexy gastrointestinal dysfunction, is cleaned by raw material of Chinese medicine, dries, pulverize respectively, cross 80 mesh sieves, be mixed evenly, adopt yellow wine as blender, adopt Chinese herbs paste conventional production process processing and fabricating to form.
Using method of the present invention is, every day one pastes, and is affixed on umbilical part, within 24 hours, changes one and pastes.
In the present invention, Cortex Eucommiae sweet in the mouth, warm in nature.There are liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, admittedly through antiabortive effect.Can treat the lumbago and skelalgia or aching and limp unable that insufficiency of kidney-YANG causes, born of the same parents' tire that deficiency of liver-QI causes is not solid, the diseases such as scrotum pruritus due to damp pathogen.There is rubbish in purged body, strengthen human body cell substance metabolism, prevent muscle skeleton aging, balanced human's blood pressure, decomposer inner cholesterol, reduces body fat, recovers blood vessel elasticity, diuresis heat clearing away, broad-spectrum antiseptic, stimulating central nervous system, improves leukocyte pharmacological action.Eupolyphaga Seu Steleophaga has removing blood stasis, effect of reunion of fractured tendons and bones.For traumatic injury, the injury of tendon and muscle is fractured, blood stasis amenorrhea, and postpartum stagnation is suffered from abdominal pain, addiction abdominal mass mass in the abdomen.Rhizoma Alpiniae Officinarum warming stomach for dispelling cold, help digestion pain relieving.For coldness and pain in the epigastrium, gastrofrigid vomiting, belch acid regurgitation.Catharsii molossi is calmed the frightened, removing blood stasis with potent drugs, relieving constipation, counteracting toxic substances.Control infantile convulsion, demented, lump in the abdomen, dysphagia and regurgitation, abdominal distention constipation, gonorrhea, infantile malnutrition, dysentery, anal fistula, furuncle swells, malignant boil.Cortex Moutan clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.Semen Persicae has blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, effect of relieving cough and asthma.For amenorrhea dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, lung abscess acute appendicitis, injury from falling down, dryness of the intestine constipation, cough and asthma.The expectorant of stir-baked FRUCTUS PERILLAE sending down the abnormal ascending QI, relieving cough and asthma, loosening bowel to relieve constipation.QI rising in reverse order is stopped up, cough and asthma, dryness of the intestine constipation for expectorant.Folium Artemisiae Argyi has warming the meridian, dries, cold expelling, hemostasis, antiinflammatory, relieving asthma, cough-relieving, the effect such as antiabortive, antiallergic.Flos Carthami is warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.Ramulus Cinnamomi diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.Rhizoma Sparganii has removing blood stasis circulation of qi promoting, effect of removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, dysmenorrhea, blood stasis amenorrhea, obstruction of qi in the chest and cardialgia, food stagnation distending pain.Flos Chrysanthemi is sweet, be slightly cold, and has loose wind heat, suppressing the hyperactive liver improving eyesight, disappears and cough effect of pain relieving, be used for the treatment of the disease Be very effective such as headache is dizzy, conjunctival congestion and swelling pain, anemopyretic cold, cough, also have effect of refreshment.Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by effect of wind-cold damp pathogen.Cure mainly YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, arthralgia due to cold-dampnes etc.Radix Salviae Miltiorrhizae has blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, and clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1:
Treat a Chinese medicine for ICU patients with cerebral apoplexy gastrointestinal dysfunction, be made up of the raw material of following weight portion:
Cortex Eucommiae 2-6 part, Eupolyphaga Seu Steleophaga 1-5 part, Rhizoma Alpiniae Officinarum 2-10 part, Catharsii molossi 1-5 part, Cortex Moutan 2-10 part, Semen Persicae 3-5 part, stir-baked FRUCTUS PERILLAE 6-8 part, Folium Artemisiae Argyi 5-8 part, Flos Carthami 3-10 part, Ramulus Cinnamomi 2-5 part, Rhizoma Sparganii 3-6 part, Flos Chrysanthemi 5-8 part, Radix Aconiti Lateralis Preparata 3-6 part, Radix Salviae Miltiorrhizae 1-5 part.Raw material of Chinese medicine is cleaned, dries, pulverize respectively, cross 80 mesh sieves, be mixed evenly, adopt yellow wine as blender, adopt Chinese herbs paste conventional production process processing and fabricating to form.
Embodiment 2:
Treat a Chinese medicine for ICU patients with cerebral apoplexy gastrointestinal dysfunction, be made up of the raw material of following weight portion:
The Cortex Eucommiae 6 parts, Eupolyphaga Seu Steleophaga 1 part, Rhizoma Alpiniae Officinarum 2 parts, Catharsii molossi 5 parts, Cortex Moutan 2 parts, 5 parts, Semen Persicae, stir-baked FRUCTUS PERILLAE 6 parts, Folium Artemisiae Argyi 8 parts, 3 parts, Flos Carthami, Ramulus Cinnamomi 2 parts, Rhizoma Sparganii 6 parts, Flos Chrysanthemi 5 parts, Radix Aconiti Lateralis Preparata 6 parts, Radix Salviae Miltiorrhizae 5 parts.Raw material of Chinese medicine is cleaned, dries, pulverize respectively, cross 80 mesh sieves, be mixed evenly, adopt yellow wine as blender, adopt Chinese herbs paste conventional production process processing and fabricating to form.
Medicinal liquid embodiment 1 prepared has carried out clinical trial, specific as follows:
84 routine ICU apoplexy are merged gastrointestinal dysfunction patient and is divided into treatment group and matched group at random, often organize 42 examples.
Matched group adopts western medicine routine treatment, and treatment group gives applying Chinese medicine to the umbilicus treatment on the basis for the treatment of of control group.Observe patient borborygmus recovery time, passage of gas by anus defecation time, gastrointestinal function scoring situation, tolerance enteral nutrition situation, MODS incidence rate and case fatality rate.
Result: treatment group borborygmus recovery time, micturition time, tolerance enteral nutrition time and anus defecation time are all short than the matched group time, and compare between group, difference all has statistical significance (P < 0.05).
After two groups of treatments, gastrointestinal function scoring reduces before all comparatively treating, compare in group, difference all has statistical significance (P < 0.05), and treatment group gastrointestinal function scoring reduction is better than matched group (P < 0.05).
Treatment group MODS incidence rate, case fatality rate, all lower than matched group, compare between group, and difference all has statistical significance (P < 0.05).
Applying Chinese medicine to the umbilicus effectively can promote the recovery of patients with cerebral apoplexy gastrointestinal function, shortens gastrointestinal functions resumed, contributes to the recovery of Post stroke neurologic impairment, improve apoplexy prognosis, reduces incidence rate and the case fatality rate of MODS.
Claims (4)
1. treat a Chinese medicine for ICU patients with cerebral apoplexy gastrointestinal dysfunction, be made up of the raw material of following weight portion:
Cortex Eucommiae 2-6 part, Eupolyphaga Seu Steleophaga 1-5 part, Rhizoma Alpiniae Officinarum 2-10 part, Catharsii molossi 1-5 part, Cortex Moutan 2-10 part, Semen Persicae 3-5 part, stir-baked FRUCTUS PERILLAE 6-8 part, Folium Artemisiae Argyi 5-8 part, Flos Carthami 3-10 part, Ramulus Cinnamomi 2-5 part, Rhizoma Sparganii 3-6 part, Flos Chrysanthemi 5-8 part, Radix Aconiti Lateralis Preparata 3-6 part, Radix Salviae Miltiorrhizae 1-5 part.
2. a kind of Chinese medicine for the treatment of ICU patients with cerebral apoplexy gastrointestinal dysfunction as claimed in claim 1, is made up of the raw material of following weight portion:
The Cortex Eucommiae 6 parts, Eupolyphaga Seu Steleophaga 1 part, Rhizoma Alpiniae Officinarum 2 parts, Catharsii molossi 5 parts, Cortex Moutan 2 parts, 5 parts, Semen Persicae, stir-baked FRUCTUS PERILLAE 6 parts, Folium Artemisiae Argyi 8 parts, 3 parts, Flos Carthami, Ramulus Cinnamomi 2 parts, Rhizoma Sparganii 6 parts, Flos Chrysanthemi 5 parts, Radix Aconiti Lateralis Preparata 6 parts, Radix Salviae Miltiorrhizae 5 parts.
3. a kind of Chinese medicine for the treatment of ICU patients with cerebral apoplexy gastrointestinal dysfunction as claimed in claim 1, is made up of the raw material of following weight portion:
The Cortex Eucommiae 2 parts, Eupolyphaga Seu Steleophaga 5 parts, Rhizoma Alpiniae Officinarum 10 parts, Catharsii molossi 1 part, Cortex Moutan 10 parts, 3 parts, Semen Persicae, stir-baked FRUCTUS PERILLAE 8 parts, Folium Artemisiae Argyi 5 parts, 10 parts, Flos Carthami, Ramulus Cinnamomi 5 parts, Rhizoma Sparganii 3 parts, Flos Chrysanthemi 8 parts, Radix Aconiti Lateralis Preparata 3 parts, Radix Salviae Miltiorrhizae 1 part.
4. preparation as arbitrary in claim 1-3 as described in a kind of method for the treatment of the Chinese medicine of ICU patients with cerebral apoplexy gastrointestinal dysfunction, it is characterized in that:
Raw material of Chinese medicine is cleaned, dries, pulverize respectively, cross 80 mesh sieves, be mixed evenly, adopt yellow wine as blender, adopt Chinese herbs paste conventional production process processing and fabricating to form.
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103656450A (en) * | 2013-12-10 | 2014-03-26 | 柳州市中医院 | Traditional Chinese medicine for treating and/or preventing gastrointestinal dysfunction caused by critical diseases |
KR20140132551A (en) * | 2013-05-08 | 2014-11-18 | (주)리즈바이오텍 | Complex plant extracts containing anti-Helicobacter pylori substance treating gastritis and preventing gastric diseases |
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KR20140132551A (en) * | 2013-05-08 | 2014-11-18 | (주)리즈바이오텍 | Complex plant extracts containing anti-Helicobacter pylori substance treating gastritis and preventing gastric diseases |
CN103656450A (en) * | 2013-12-10 | 2014-03-26 | 柳州市中医院 | Traditional Chinese medicine for treating and/or preventing gastrointestinal dysfunction caused by critical diseases |
Non-Patent Citations (1)
Title |
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唐晓等: "中药敷脐结合中药灌肠治疗ICU脑卒中患者胃肠功能障碍48例", 《湖南中医杂志》 * |
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Application publication date: 20160323 |