CN105412746A - Composite traditional Chinese medicine for treating phthisis and preparation method thereof - Google Patents

Abstract

The invention discloses a composite traditional Chinese medicine for treating phthisis and a preparation method thereof. The traditional Chinese medicine is prepared from, by weight, 10-15 parts of cortex lycii radicis, 15-20 parts of herba houttuyniae, 5-10 parts of hedera helix essence extracting solution, 5-10 parts of milk thistle, 15-20 parts of radix stemonae, 15-20 parts of rhizoma anemarrhenae, 15-20 parts of milkvetch roots, 15-20 parts of upright ladybell roots, 3-10 parts of solms-laubachia pulcherrima extract, 3-10 parts of purple garlic extracting solution, 5-15 parts of Japanese ginseng, 10-15 parts of herba thesii, 10-15 parts of white mulberry root-bark, 10-15 parts of common pratia herb, 10-15 parts of herb of cape-gooseberry and 10-18 parts of radix rubiae. According to the composite traditional Chinese medicine for treating the phthisis and the preparation method thereof, traditional Chinese medicine preparations and plant extracts are perfectly matched and combined with a unique preparation technology, so that effective components in the traditional Chinese medicine preparations are fully dissolved out, the toxic and side effects of the obtained medicine are small, the treatment effect is good, and meanwhile drug resistance is not prone to occurrence.

Description

One treats phthisical combination of Chinese medicine and preparation method thereof

Technical field

The present invention relates to tuberculosis treatment field, be specifically related to one and treat phthisical combination of Chinese medicine and preparation method thereof.

Background technology

Tuberculosis (Tuberculosis) is a kind of chronic infectious disease, and fall ill when resistance of human body is low because infecting tubercule bacillus (being called for short tulase), the serious harm people is healthy.Spitting of blood disease occurrence rate in pulmonary tuberculosis patient reaches 25% ~ 30%, and has empty person especially many.Modern medicine is thought, hemoptysis of pulmonary tuberculosis be due to the capillary permeability of inflammatory lesions increase, thin vessels damage, empty wall are comparatively large, aneurysm rupture and the sputum mixed with blood caused, whole mouth spitting of blood or massive hemoptysis.

In theory of Chinese medical science, pulmonary tuberculosis can belong to " pulmonary tuberculosis " category, is by the chronic debilitating infectiousness illness of pulmonary infected caused by " illness worm ", visible cough, spitting of blood, hectic fever, night sweat, the primary symptom such as to become thin.At the beginning of primary disease, diseased region is mainly at lung, and consumptive disease insect bite lung, lung yin is impaired and cough, and lung network is impaired and spit blood.Hyperactivity of fire caused by deficiency of YIN, the absurd row of forcing blood then massive hemoptysis.

Current antituberculotics, domestic conventional mainly these five: isoniazid, rifampicin, pyrazinamide, ethambutol, streptomycin.But these five is all Western medicine, and be oral tablet or capsule substantially.Tuberculosis pathogenic bacteria has the feature of easily variation, therefore easily make the chemicals of single structure lose efficacy very soon and produce drug resistance, even if regular period not drug resistance, but increasing to the side effect of liver and kidney and other organs after those medicine Long-term Orals, can't bear to stand, after drug withdrawal also easily repeatedly; Not only wound body but also cure bad.

Summary of the invention

For solving the problem, the invention provides one and treating phthisical combination of Chinese medicine and preparation method thereof, pure natural extracts, and toxic and side effects is little, and therapeutic effect is good, not easily produces drug resistance simultaneously.

For achieving the above object, the technical scheme that the present invention takes is:

One treats phthisical combination of Chinese medicine, is prepared from by the raw material of following weight portion:

Cortex Lycii 10 ~ 15 parts, Herba Houttuyniae 15 ~ 20 parts, Hedera nepalensis var.sinensis essence extracting solution 5 ~ 10 parts, Milk Thistle 5 ~ 10 parts, the Radix Stemonae 15 ~ 20 parts, the Rhizoma Anemarrhenae 15 ~ 20 parts, the Radix Astragali 15 ~ 20 parts, Radix Adenophorae 15 ~ 20 parts, Solms-Laubachia extract 3 ~ 10 parts, purple garlic extracting solution 3 ~ 10 parts, Rhizoma Panacis Japonici 5 ~ 15 parts, Herba Thesii 10 ~ 15 parts, Cortex Mori 10 ~ 15 parts, Herba pratiae begonifoliae 10 ~ 15 parts, Physalis minima L. 10 ~ 15 parts, 10 ~ 18 parts, Radix Rubiae.

Present invention also offers above-mentioned a kind of preparation method for the treatment of phthisical combination of Chinese medicine, comprise the steps:

S1, take each component by formula according to claim 1;

S2, the Cortex Lycii taken, Herba Houttuyniae, Milk Thistle, the Radix Stemonae, the Rhizoma Anemarrhenae, the Radix Astragali, Radix Adenophorae, Rhizoma Panacis Japonici, Herba Thesii, Cortex Mori, Herba pratiae begonifoliae, Physalis minima L. and Radix Rubiae are placed in autoclave, add the water just in time flooding medical material, passing into pressure in nitrogen to autoclave is 0.7 ~ 1.5MPa, process 8 ~ 25min; Then passing into rapidly pressure in steam to autoclave is 1.5 ~ 2.5Mpa, steaming and decocting 6 ~ 10h, filters, medicinal residues are to add water reflux, extract, 2 time at 1: 10 in mass ratio, and each reflux, extract, 1 hour, merges 3 extracting solution, room temperature is concentrated into relative density 1.10 ~ 1.20, obtains mixture A;

S3, the mixture A of gained is placed in mixing and blending machine, add Hedera nepalensis var.sinensis essence extracting solution, Solms-Laubachia extract, purple garlic extracting solution that step S1 takes successively, mix and blend 5 ~ 10min, obtains mixture B;

S4, by the mixture B of gained by the blended pelletize of double screw extruder, obtain finished product, screw extruder rotating speed is 600 ~ 900rpm, and pressure is 2 ~ 3MPa.

Preferably, be prepared from by the raw material of following weight portion:

Cortex Lycii 12.5 parts, Herba Houttuyniae 17.5 parts, Hedera nepalensis var.sinensis essence extracting solution 7.5 parts, Milk Thistle 7.5 parts, the Radix Stemonae 17.5 parts, the Rhizoma Anemarrhenae 17.5 parts, the Radix Astragali 17.5 parts, Radix Adenophorae 17.5 parts, Solms-Laubachia extract 6.5 parts, purple garlic extracting solution 6.5 parts, Rhizoma Panacis Japonici 10 parts, Herba Thesii 12.5 parts, Cortex Mori 12.5 parts, Herba pratiae begonifoliae 12.5 parts, Physalis minima L. 12.5 parts, 14 parts, Radix Rubiae.

The present invention has following beneficial effect:

By Chinese medicine preparation and plant extract being carried out perfect cooperation, and collaborative unique preparation technology, the effective ingredient in Chinese medicine preparation is fully separated out, and gained poisonous side effect of medicine is little, and therapeutic effect is good, not easily produces drug resistance simultaneously.

Detailed description of the invention

In order to make objects and advantages of the present invention clearly understand, below in conjunction with embodiment, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.

Embodiment 1

S1, take Cortex Lycii 10 parts, Herba Houttuyniae 15 parts, Hedera nepalensis var.sinensis essence extracting solution 5 parts, Milk Thistle 5 parts, the Radix Stemonae 15 parts, the Rhizoma Anemarrhenae 15 parts, the Radix Astragali 15 parts, Radix Adenophorae 15 parts, Solms-Laubachia extract 3 parts, purple garlic extracting solution 3 parts, Rhizoma Panacis Japonici 5 parts, Herba Thesii 10 parts, Cortex Mori 10 parts, Herba pratiae begonifoliae 10 parts, Physalis minima L. 10 parts, 10 parts, Radix Rubiae;

S2, the Cortex Lycii taken, Herba Houttuyniae, Milk Thistle, the Radix Stemonae, the Rhizoma Anemarrhenae, the Radix Astragali, Radix Adenophorae, Rhizoma Panacis Japonici, Herba Thesii, Cortex Mori, Herba pratiae begonifoliae, Physalis minima L. and Radix Rubiae are placed in autoclave, add the water just in time flooding medical material, passing into pressure in nitrogen to autoclave is 0.7MPa, process 825min; Then passing into rapidly pressure in steam to autoclave is 1.5Mpa, steaming and decocting 10h, filters, and medicinal residues are to add water reflux, extract, 2 times at 1: 10 in mass ratio, each reflux, extract, 1 hour, and merge 3 extracting solution, room temperature is concentrated into relative density 1.10, obtains mixture A;

S3, the mixture A of gained is placed in mixing and blending machine, add Hedera nepalensis var.sinensis essence extracting solution, Solms-Laubachia extract, purple garlic extracting solution that step S1 takes successively, mix and blend 5min, obtains mixture B;

S4, by the mixture B of gained by the blended pelletize of double screw extruder, obtain finished product, screw extruder rotating speed is 600rpm, and pressure is 2MPa.

Embodiment 2

S1, take Cortex Lycii 15 parts, Herba Houttuyniae 20 parts, Hedera nepalensis var.sinensis essence extracting solution 10 parts, Milk Thistle 10 parts, the Radix Stemonae 20 parts, the Rhizoma Anemarrhenae 20 parts, the Radix Astragali 20 parts, Radix Adenophorae 20 parts, Solms-Laubachia extract 10 parts, purple garlic extracting solution 10 parts, Rhizoma Panacis Japonici 15 parts, Herba Thesii 15 parts, Cortex Mori 15 parts, Herba pratiae begonifoliae 15 parts, Physalis minima L. 15 parts, 18 parts, Radix Rubiae;

S2, the Cortex Lycii taken, Herba Houttuyniae, Milk Thistle, the Radix Stemonae, the Rhizoma Anemarrhenae, the Radix Astragali, Radix Adenophorae, Rhizoma Panacis Japonici, Herba Thesii, Cortex Mori, Herba pratiae begonifoliae, Physalis minima L. and Radix Rubiae are placed in autoclave, add the water just in time flooding medical material, passing into pressure in nitrogen to autoclave is 1.5MPa, process 8min; Then passing into rapidly pressure in steam to autoclave is 2.5Mpa, steaming and decocting 6h, filters, and medicinal residues are to add water reflux, extract, 2 times at 1: 10 in mass ratio, each reflux, extract, 1 hour, and merge 3 extracting solution, room temperature is concentrated into relative density 1.20, obtains mixture A;

S3, the mixture A of gained is placed in mixing and blending machine, add Hedera nepalensis var.sinensis essence extracting solution, Solms-Laubachia extract, purple garlic extracting solution that step S1 takes successively, mix and blend 10min, obtains mixture B;

S4, by the mixture B of gained by the blended pelletize of double screw extruder, obtain finished product, screw extruder rotating speed is 900rpm, and pressure is 3MPa.

Embodiment 3

S1, take Cortex Lycii 12.5 parts, Herba Houttuyniae 17.5 parts, Hedera nepalensis var.sinensis essence extracting solution 7.5 parts, Milk Thistle 7.5 parts, the Radix Stemonae 17.5 parts, the Rhizoma Anemarrhenae 17.5 parts, the Radix Astragali 17.5 parts, Radix Adenophorae 17.5 parts, Solms-Laubachia extract 6.5 parts, purple garlic extracting solution 6.5 parts, Rhizoma Panacis Japonici 10 parts, Herba Thesii 12.5 parts, Cortex Mori 12.5 parts, Herba pratiae begonifoliae 12.5 parts, Physalis minima L. 12.5 parts, 14 parts, Radix Rubiae;

S2, the Cortex Lycii taken, Herba Houttuyniae, Milk Thistle, the Radix Stemonae, the Rhizoma Anemarrhenae, the Radix Astragali, Radix Adenophorae, Rhizoma Panacis Japonici, Herba Thesii, Cortex Mori, Herba pratiae begonifoliae, Physalis minima L. and Radix Rubiae are placed in autoclave, add the water just in time flooding medical material, passing into pressure in nitrogen to autoclave is 1.1MPa, process 16.5min; Then passing into rapidly pressure in steam to autoclave is 2Mpa, steaming and decocting 8h, filters, and medicinal residues are to add water reflux, extract, 2 times at 1: 10 in mass ratio, each reflux, extract, 1 hour, and merge 3 extracting solution, room temperature is concentrated into relative density 1.15, obtains mixture A;

S3, the mixture A of gained is placed in mixing and blending machine, add Hedera nepalensis var.sinensis essence extracting solution, Solms-Laubachia extract, purple garlic extracting solution that step S1 takes successively, mix and blend 7.5min, obtains mixture B;

S4, by the mixture B of gained by the blended pelletize of double screw extruder, obtain finished product, screw extruder rotating speed is 750rpm, and pressure is 2.5MPa.

The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (3)

1. treat a phthisical combination of Chinese medicine, it is characterized in that, be prepared from by the raw material of following weight portion:

Cortex Lycii 10 ~ 15 parts, Herba Houttuyniae 15 ~ 20 parts, Hedera nepalensis var.sinensis essence extracting solution 5 ~ 10 parts, Milk Thistle 5 ~ 10 parts, the Radix Stemonae 15 ~ 20 parts, the Rhizoma Anemarrhenae 15 ~ 20 parts, the Radix Astragali 15 ~ 20 parts, Radix Adenophorae 15 ~ 20 parts, Solms-Laubachia extract 3 ~ 10 parts, purple garlic extracting solution 3 ~ 10 parts, Rhizoma Panacis Japonici 5 ~ 15 parts, Herba Thesii 10 ~ 15 parts, Cortex Mori 10 ~ 15 parts, Herba pratiae begonifoliae 10 ~ 15 parts, Physalis minima L. 10 ~ 15 parts, 10 ~ 18 parts, Radix Rubiae.

2. a kind of preparation method for the treatment of phthisical combination of Chinese medicine as claimed in claim 1, is characterized in that, comprise the steps:

S1, take each component by formula according to claim 1;

S2, the Cortex Lycii taken, Herba Houttuyniae, Milk Thistle, the Radix Stemonae, the Rhizoma Anemarrhenae, the Radix Astragali, Radix Adenophorae, Rhizoma Panacis Japonici, Herba Thesii, Cortex Mori, Herba pratiae begonifoliae, Physalis minima L. and Radix Rubiae are placed in autoclave, add the water just in time flooding medical material, passing into pressure in nitrogen to autoclave is 0.7 ~ 1.5MPa, process 8 ~ 25min; Then passing into rapidly pressure in steam to autoclave is 1.5 ~ 2.5Mpa, steaming and decocting 6 ~ 10h, filters, medicinal residues are to add water reflux, extract, 2 time at 1: 10 in mass ratio, and each reflux, extract, 1 hour, merges 3 extracting solution, room temperature is concentrated into relative density 1.10 ~ 1.20, obtains mixture A;

S3, the mixture A of gained is placed in mixing and blending machine, add Hedera nepalensis var.sinensis essence extracting solution, Solms-Laubachia extract, purple garlic extracting solution that step S1 takes successively, mix and blend 5 ~ 10min, obtains mixture B;

S4, by the mixture B of gained by the blended pelletize of double screw extruder, obtain finished product, screw extruder rotating speed is 600 ~ 900rpm, and pressure is 2 ~ 3MPa.

3. one according to claim 1 is treated phthisical combination of Chinese medicine and be it is characterized in that, is prepared from by the raw material of following weight portion:

Cortex Lycii 12.5 parts, Herba Houttuyniae 17.5 parts, Hedera nepalensis var.sinensis essence extracting solution 7.5 parts, Milk Thistle 7.5 parts, the Radix Stemonae 17.5 parts, the Rhizoma Anemarrhenae 17.5 parts, the Radix Astragali 17.5 parts, Radix Adenophorae 17.5 parts, Solms-Laubachia extract 6.5 parts, purple garlic extracting solution 6.5 parts, Rhizoma Panacis Japonici 10 parts, Herba Thesii 12.5 parts, Cortex Mori 12.5 parts, Herba pratiae begonifoliae 12.5 parts, Physalis minima L. 12.5 parts, 14 parts, Radix Rubiae.