CN105411898A - 一种含樱花浸渍膏脂质体的护肤精华液 - Google Patents

一种含樱花浸渍膏脂质体的护肤精华液 Download PDF

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CN105411898A
CN105411898A CN201510826758.5A CN201510826758A CN105411898A CN 105411898 A CN105411898 A CN 105411898A CN 201510826758 A CN201510826758 A CN 201510826758A CN 105411898 A CN105411898 A CN 105411898A
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练英铎
杨惠波
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Opal Cosmetics Huizhou Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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Abstract

本发明属于日化领域,具体涉及一种含樱花浸渍膏脂质体的护肤精华液。一种含樱花浸渍膏脂质体的护肤精华液由如下重量份的组分组成:樱花浸渍膏脂质体0.5~10%,卡波树脂0.05~5%,蘑菇葡聚糖0.1~3%,透明质酸钠?0.01~1%,尿囊素0.1~1%,吡咯烷酮羧酸钠0.5~5%,防腐剂0~0.5%,有机碱0.01~0.5%,余量为水。本发明含有经过脂质体包裹的樱花浸渍膏,天然温和,复配皮肤所需营养成分,保湿营养时间明显优于市售同类产品,紧致毛孔,滋养皮肤。

Description

一种含樱花浸渍膏脂质体的护肤精华液
技术领域
本发明属于日化领域,具体涉及一种含樱花浸渍膏脂质体的护肤精华液。
背景技术
研究表明樱花提取物富含A、B、E等天然维生素及黄酮类物质,具有很好的抗炎、抗氧化、抗菌、抗肿瘤以及抑制血小板聚集的生物活性,同时樱花提取物能够收缩毛孔,强化黏膜,促进糖分代谢和平衡皮肤油脂。
皮肤的衰老问题是美容护肤研究的一大课题,造成皮肤衰老的原因主要有人体自身新陈代谢及外部环境影响等因素,皮肤的氧化损伤是引发皮肤衰老的主要原因之一,防止皮肤的氧化损伤对于保护皮肤组织正常结构和功能,延缓皮肤衰老具有重要意义,抗氧化活性成分在一定程度上能帮助皮肤抵御氧化损伤。近几年,天然抗氧化剂成为研究热点,对天然抗氧化剂的研究越来越多,樱花作为天然抗氧化剂在抗皮肤衰老方面具有良好的前景。
在现有技术中,樱花提取物在护肤中的使用仍以直接添加到配方中为主,未对樱花提取物进行后期处理,使其发挥功效的空间有限。
发明内容
本发明所要解决的技术问题是提供一种含樱花浸渍膏脂质体的护肤精华液。
本发明所要解决的技术问题通过以下技术方案予以实现:
一种含樱花浸渍膏脂质体的护肤精华液,由如下重量百分比的组分组成:
樱花浸渍膏脂质体0.5~10%;
卡波树脂0.05~5%;
蘑菇葡聚糖0.1~3%;
透明质酸钠0.01~1%;
尿囊素0.1~1%;
吡咯烷酮羧酸钠0.5~5%;
防腐剂0~0.5%;
有机碱0.01~0.5%;
余量为水。
进一步的,所述樱花浸渍膏脂质体含有樱花浸渍膏,大豆卵磷脂和胆固醇,大豆卵磷脂与胆固醇重量比为1:6~1:13,大豆卵磷脂和胆固醇总重量与樱花浸渍膏重量比为1:0.2~1:0.8。
进一步的,樱花浸渍膏脂质体制备方法如下:
(1)将干燥粉碎后的樱花粉末进行超声提取;
(2)完成超声提取后,对由超声提取机的排液口排出的分离液进行浓缩,得到樱花浸渍膏;
(3)按重量份数精密称取配方量的大豆卵磷脂,胆固醇,于无水乙醇中混合均匀,将其注入樱花浸渍膏中,并用NaOH溶液调pH到6.8,使其充分混合均匀,搅拌25min,得到的悬浮液冷冻干燥去除溶剂,得到冻干的包含樱花浸渍膏的脂质体。
本发明具有如下有益效果:
本发明的樱花浸渍膏脂质体,与传统樱花提取物相比,活性物含量高,经过脂质体包埋处理的樱花浸渍膏,作用在皮肤时缓释控制皮肤对樱花活性物的吸收,作用时间长,吸收效果好。与添加的蘑菇葡聚糖,透明质酸钠,尿囊素,吡咯烷酮羧酸钠这几种皮肤营养因子协同作用,帮助皮肤恢复弹性,锁住水分,抵抗外部环境造成的皮肤损伤,紧致毛孔,滋养皮肤。
具体实施方式
下面结合实施例对本发明进行详细的说明,实施例仅是本发明的优选实施方式,不是对本发明的限定。
以实施例1为主,对本发明进行进一步的说明。
含樱花浸渍膏脂质体的护肤精华液制备方法如下:
(1)樱花浸渍膏脂质体制备
(a)将干燥粉碎后的樱花粉末进行超声提取;
(b)完成超声提取后,对由超声提取机的排液口排出的分离液进行浓缩,得到樱花浸渍膏;
(c)按重量份数精密称取大豆卵磷脂1重量份,胆固醇9重量份,樱花浸渍膏5重量份,将大豆卵磷脂和胆固醇溶于无水乙醇中混合均匀,混合均匀的液体注入樱花浸渍膏中,并用NaOH溶液调pH到6.8,使其充分混合均匀,搅拌25min,得到的悬浮液冷冻干燥去除无水乙醇,得到冻干的包含樱花浸渍膏的脂质体15重量份;
(2)含樱花浸渍膏脂质体的护肤精华液制备
(a)取配方重量份的水分置于配置容器中,加入2.5重量份的卡波树脂,快速搅拌分散均匀,然后用有机碱中和pH到6.8~7,中和完成后,向容器中加入1.5重量份蘑菇葡聚糖,搅拌均匀;
(b)向容器中继续先后加入0.01重量份的透明质酸钠,0.3重量份的尿囊素,0.5重量份的吡咯烷酮羧酸钠,0.25重量份的防腐剂,分散搅拌均匀;
(c)最后重新用有机碱调节pH到5.5~6之间,得到含樱花浸渍膏脂质体的护肤精华液。
本发明以常规的护肤精华液方式使用,主要包括以下几个步骤:
使用有效量的本发明产品均匀地涂在身体部位,轻柔按摩一分钟。
下表为志愿者对含樱花浸渍膏脂质体精华液及参照样本效果评价分数:
志愿者 1 2 3 4 5 6 7 8 9 10
实施例1 7 8 9 9 7 9 9 7 8 8.5
实施例2 8 8 8.5 9 8 9 9 8 9 8
实施例3 10 9.5 8.5 9 8.5 9.5 9 8.5 9.5 8
对比例 6 5 6 6 3 5 6 6 6 6
注:志愿者评价得到的评估结果。滋润保湿、抗氧化调理效果:10分最好,0分最差。其中,对比例为市售同类含樱花提取物的精华液产品
评估结果表明本发明护肤精华液能带来优越的滋润保湿及抗氧化调理效果,效果明显优于市售同类产品,说明经过脂质体包埋的樱花浸渍膏更能发挥樱花提取物的功效作用,对皮肤的护理作用明显。
下表志愿者对本樱花浸渍膏脂质体精华液效果评价结果
志愿者 1 2 3 4 5
效果的评价 调理效果优良 滋润效果优良调理效果优良 质感柔滑,调理效果优良 调理效果优良 调理效果优良
志愿者 6 7 8 9 10
效果的评价 皮肤柔软,效果明显 调理效果优良,保湿效果优良 调理效果优良,滋润效果优良 调理效果优良,防护效果优良 调理效果优良,补水效果优良
评估结果表明,本发明樱花浸渍膏脂质体精华液有很好的滋润保湿及抗氧化调理效果,帮助皮肤抵抗外界环境造成的皮肤损伤,减缓皮肤衰老。

Claims (3)

1.一种含樱花浸渍膏脂质体的护肤精华液,其特征在于:由如下重量百分比的组分组成:
樱花浸渍膏脂质体0.5~10%;
卡波树脂0.05~5%;
蘑菇葡聚糖0.1~3%;
透明质酸钠0.01~1%;
尿囊素0.1~1%;
吡咯烷酮羧酸钠0.5~5%;
防腐剂0~0.5%;
有机碱0.01~0.5%;
余量为水。
2.根据权利要求1所述的含樱花浸渍膏脂质体的护肤精华液,其特征在于,所述樱花浸渍膏脂质体含有樱花浸渍膏,大豆卵磷脂和胆固醇,大豆卵磷脂与胆固醇重量比为1:6~1:13,大豆卵磷脂和胆固醇总重量与樱花浸渍膏重量比为1:0.2~1:0.8。
3.根据权利要求1所述的含樱花浸渍膏脂质体的护肤精华液,其特征在于,樱花浸渍膏脂质体制备方法如下:
(1)将干燥粉碎后的樱花粉末进行超声提取;
(2)完成超声提取后,对由超声提取机的排液口排出的分离液进行浓缩,得到樱花浸渍膏;
(3)按重量份数精密称取配方量的大豆卵磷脂,胆固醇,于无水乙醇中混合均匀,将其注入樱花浸渍膏中,并用NaOH溶液调pH到6.8,使其充分混合均匀,搅拌25min,得到的悬浮液冷冻干燥去除溶剂,得到冻干的包含樱花浸渍膏的脂质体。
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113288841A (zh) * 2021-06-30 2021-08-24 花安堂生物科技集团有限公司 一种面膜液及其制备方法
CN113368055A (zh) * 2021-06-30 2021-09-10 花安堂生物科技集团有限公司 一种纳米脂质体乳剂的制备方法

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