CN105403689A - Method for processing biosensor test paper by using laser resistance adjusting system - Google Patents

Method for processing biosensor test paper by using laser resistance adjusting system Download PDF

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Publication number
CN105403689A
CN105403689A CN201510322980.1A CN201510322980A CN105403689A CN 105403689 A CN105403689 A CN 105403689A CN 201510322980 A CN201510322980 A CN 201510322980A CN 105403689 A CN105403689 A CN 105403689A
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CN
China
Prior art keywords
test paper
laser
resistance
biology sensor
resistive element
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CN201510322980.1A
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Chinese (zh)
Inventor
张文伶
顾晓华
佘志新
楼凯
杨清刚
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Hangzhou Wei Ce Bioisystech Co Ltd
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Hangzhou Wei Ce Bioisystech Co Ltd
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Priority to CN201510322980.1A priority Critical patent/CN105403689A/en
Publication of CN105403689A publication Critical patent/CN105403689A/en
Pending legal-status Critical Current

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  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The present invention relates to a method for processing biosensor test paper by using a laser resistance adjusting system, wherein the resistor body on biosensor test paper is subjected to precise processing again through a laser resistance adjusting way. According to the method, biosensor test paper is used; and the pulse laser beam output by a laser resistance adjusting system is focused into a small and high-energy-density laser pulse to bombard the resistor body slurry on the biosensor test paper so as to rapidly gasify the cut resistor slurry, such that the aspect ratio of the resistor body is effectively changed, and the resistance adjusting precision of the adjusted resistor body achieves 0.01-0.1%. According to the present invention, the laser resistance adjusting process has characteristics of rapidness, high precision (achieves 0.01-0.1%), wide resistance value adjusting range (0.1-10000 [omega]), and no influence on characteristics of surrounding elements, is suitable for mass production, and the sensing precision of the biosensor test paper obtained through secondary processing is high; and the method can be applied in any biosensor test paper including the biosensors using optical principles and electrochemical principles, and the recognition information more than the recognition information of the background technology can be obtained.

Description

Adopt the method for laser resistor trimming system processing biology sensor test paper
Technical field
The present invention relates to a kind of mode by laser resistor trimming to reach a kind of method adopting laser resistor trimming system to process biology sensor test paper of the resistive element on biology sensor test paper being carried out again to accurately processing, belong to biology sensor finishing and manufacture field.
Background technology
CN1839315A, title " on a biosensor test strip to the system and method for information coding ", this test macro comprises: a test chart comprising the connector with at least ten contacts; With adapt to the test-strips inserting test chart connector, this test-strips comprises: have a surperficial substrate; At least ten contact discs formed from the teeth outwards; Wherein when test-strips inserts test chart connector, these at least ten contacts are formed with corresponding at least ten contact discs and contact.This invention by making conduction electrically conductive links on biology sensor test paper, supporting instrument is by reading conduction or the morphogenetic different array configuration of non-conductive shape of this electrically conductive links, i.e. one group of binary reading, judges adopt which kind of correction parameter or test which kind of target substance.But, because the size of biology sensor test paper is more limited, this patent to the lot number calibration information of test paper or when identifying different test paper, conduction or nonconducting array configuration more limited.
CN2890916Y, title " have the biological sensor chip of recognition function and the sensor of cooperation ", comprise: the substrate of a tool electrical insulating property, are equipped with a working electrode and a reference electrode in this substrate; One identifies electrode zone, and it is on substrate one end, and this identification electrode zone is coated with conductive material, and this conductive material changes with the difference of resistance value; One detection zone, it is positioned on the substrate other end, and this detection zone is connected with working electrode and reference electrode.This invention forms identified region by the material of applying conductive on biology sensor test paper, uses different conductive material to make this identified region have different resistance values, coordinates different test-purpose.This patent needs to use different conductive material or mixing to reach the object of different resistance, and this technology is to the control Deterministic Finite of resistance value, and the array configuration that can obtain is also more limited.
Summary of the invention
Purpose of design: avoid the weak point in background technology, designs a kind of mode by laser resistor trimming to reach a kind of method adopting laser resistor trimming system to process biology sensor test paper of the resistive element on biology sensor test paper being carried out again to accurately processing.
Design proposal: in order to realize above-mentioned purpose of design.The application is in the secondary processing to biology sensor test paper, laser resistor trimming (trimming) system being used for improving thick film circuit precision is used for the secondary processing of biology sensor test paper, because be difficult to realize the accurate control to resistance value separately through the control of coating or typography on test paper, and laser trimming is that the coherent light of a branch of focusing is navigated on test paper under the control of microcomputer, to treating in test paper that the resistive element slurry of tune part bombards, the resistance slurry be cut is gasified rapidly, thus the effective length breadth ratio changing resistive element, finally reach the object of accurate adjustment resistive element resistance, thus solve the defect of background technology existence, improve the accuracy of detection of biology sensor test paper.Concrete: coating or print the resistance of conduction on test paper, supporting instrument reads the size of this resistance (or the ratio between resistance) and selects should the calibration information of lot number test paper, or identifies the kind of this test paper; The resistance of the conduction that this test paper is printed reaches the object of accurate controlling resistance value by the mode of laser resistor trimming.Because coating or printing conductive material, form an identified region on biology sensor test paper.This identified region can be positioned at any position on test paper to adapt to different test paper designs and the test of matching instrument.This identified region can comprise one or more resistance.Matching instrument reads the one or more resistance of this identified region, reach select to should lot number test paper calibration information or identify the object of this test paper kind.
Laser resistor trimming system is primarily of compositions such as computer-controlled laser instrument, beam positioning systems, measuring system, image display and identification and positioning systems.It can trim resistance fast, accurately to predetermined value, and this process controls all moving components by computing machine and laser makes laser beam move on resistance and cut resistance to have come.Measuring system is while cut resistive element, by probe conjunction measuring system monitoring change in resistance, and compare with setting reference value, when measured value is consistent with setting reference value, laser pulse stops automatically, and then laser beam is transferred on the next resistance needing to trim.
Technical scheme: a kind of method adopting laser resistor trimming system to process biology sensor test paper, comprise biology sensor test paper, the laser pulse pulse laser beam that laser resistor trimming system exports being focused into very little high-energy-density bombards the resistive element slurry on biology sensor test paper, the resistance slurry be cut is gasified rapidly, thus the effective length breadth ratio changing resistive element, make the resistance trimming precision of controlled resistive element reach 0.01 ~ 0.1%.
The present invention is compared with background technology, one is that laser resistor trimming process speed is fast, precision is high (can reach 0.01 ~ 0.1%), resistance setting range wide (0.1 ~ 10000M), on the characteristic of around original paper without impact, be applicable to producing in enormous quantities, the biology sensor test paper sensing accuracy of its secondary processing is high; Two is to be applied to any biology sensor test paper, comprises the biology sensor adopting optical principle and electrochemical principle, and can obtain identifying information more more than background technology.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of biology sensor test paper; In Fig. 1,1 is insulating material, 2 is the resistive element (carbon of cog region, the high resisitivity conductive materials such as precious metal alloys (platinum, palldium alloy) or single Precious Metals-Gold, platinum), 3 and 4 is the contact (silver etc. low resistivity conductive material) of matching instrument test resistance body 2, and matching instrument is by the resistance value of contact 3 and 4 test resistance body 2.
Fig. 2 is the straight line example of biology sensor test paper.
Fig. 3 is bilinear, the multi straight example of biology sensor test paper.
Fig. 4 is the non-rectilinear class example of biology sensor test paper, comprises L-type, U-shaped, the cutting such as J type, S type.
Fig. 5 is biology sensor test paper schematic diagram; In Fig. 5,1 is insulating material, 21,22,23,24 is the resistive element (carbon of cog region, the high resisitivity conductive materials such as precious metal alloys (platinum, palldium alloy) or single Precious Metals-Gold, platinum), 3,32,33,34,4 is the contact (silver etc. low resistivity conductive material) of matching instrument test resistance 21,22,23,24.Matching instrument can distinguish four resistance arbitrary in test contact 4 and 31,32,33,34.
Fig. 6 is the simple and easy schematic diagram of laser resistor trimming device.
Embodiment
Embodiment 1: with reference to accompanying drawing 1-6.A kind of method adopting laser resistor trimming system to process biology sensor test paper, comprise biology sensor test paper, the outsourcing of biology sensor test paper system, during secondary processing, the laser pulse pulse laser beam that laser resistor trimming system exports being focused into very little high-energy-density bombards the resistive element slurry on biology sensor test paper, the resistance slurry be cut is gasified rapidly, thus the effective length breadth ratio changing resistive element, make the resistance trimming precision of controlled resistive element reach 0.01 ~ 0.1%.The resistance setting range of resistive element is 0.1 ~ 10000M.Measuring system in laser resistor trimming system is while cut resistive element, by probe conjunction measuring system monitoring change in resistance, and compare with setting reference value, when measured value is consistent with setting reference value, laser pulse stops automatically, and then laser beam is transferred on the next resistance needing to trim.
It is to be understood that: although above-described embodiment to be contrasted detailed text description to mentality of designing of the present invention; but these text descriptions; just the simple text of mentality of designing of the present invention is described; instead of the restriction to mentality of designing of the present invention; any do not exceed mentality of designing of the present invention combination, increase or amendment, all fall within the scope of protection of the present invention.

Claims (3)

1. the method adopting laser resistor trimming system to process biology sensor test paper, comprise biology sensor test paper, it is characterized in that: the laser pulse pulse laser beam that laser resistor trimming system exports being focused into very little high-energy-density bombards the resistive element slurry on biology sensor test paper, the resistance slurry be cut is gasified rapidly, thus the effective length breadth ratio changing resistive element, make the resistance trimming precision of controlled resistive element reach 0.01 ~ 0.1%.
2. the method for employing laser resistor trimming system processing biology sensor test paper according to claim 1, is characterized in that: the resistance setting range of resistive element is 0.1 ~ 10000M.
3. the method for employing laser resistor trimming system processing biology sensor test paper according to claim 1, it is characterized in that: the measuring system in laser resistor trimming system is while cut resistive element, by probe conjunction measuring system monitoring change in resistance, and compare with setting reference value, when measured value is consistent with setting reference value, laser pulse stops automatically, and then laser beam is transferred on the next resistance needing to trim.
CN201510322980.1A 2015-06-12 2015-06-12 Method for processing biosensor test paper by using laser resistance adjusting system Pending CN105403689A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110161095A (en) * 2018-02-12 2019-08-23 杭州微策生物技术有限公司 A kind of biosensor resistance adjustment laser system and its method
CN110160563A (en) * 2018-02-12 2019-08-23 杭州微策生物技术有限公司 A kind of method of biosensor resistance adjustment encoded information

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Publication number Priority date Publication date Assignee Title
GB2285138B (en) * 1993-12-27 1997-10-22 Ngk Insulators Ltd Temperature sensor
JP2000097792A (en) * 1998-09-25 2000-04-07 Matsushita Electric Works Ltd Method and apparatus for laser trimming of pressure sensor
US6882454B2 (en) * 2003-08-15 2005-04-19 Brother Kogyo Kabushiki Kaisha Multi-beam scanner
DE102005029804A1 (en) * 2005-06-27 2007-01-04 Robert Bosch Gmbh Method for adjusting a sheet resistance and a sheet resistance and a strain gauge
CN101019021A (en) * 2004-06-18 2007-08-15 霍夫曼-拉罗奇有限公司 System and method for quality assurance of a biosensor test strip
CN101156066A (en) * 2005-04-01 2008-04-02 霍夫曼-拉罗奇有限公司 System and method for coding information on a biosensor test strip
CN101692361A (en) * 2009-10-09 2010-04-07 乾坤科技股份有限公司 Resistance device for sensing current
CN103091658A (en) * 2013-02-19 2013-05-08 江苏和利普激光科技有限公司 Current sensor resistance adjusting tool
CN104091664A (en) * 2014-06-12 2014-10-08 北京锋速精密设备有限公司 Novel function curve following resistor trimming method

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2285138B (en) * 1993-12-27 1997-10-22 Ngk Insulators Ltd Temperature sensor
JP2000097792A (en) * 1998-09-25 2000-04-07 Matsushita Electric Works Ltd Method and apparatus for laser trimming of pressure sensor
US6882454B2 (en) * 2003-08-15 2005-04-19 Brother Kogyo Kabushiki Kaisha Multi-beam scanner
CN101019021A (en) * 2004-06-18 2007-08-15 霍夫曼-拉罗奇有限公司 System and method for quality assurance of a biosensor test strip
CN101156066A (en) * 2005-04-01 2008-04-02 霍夫曼-拉罗奇有限公司 System and method for coding information on a biosensor test strip
DE102005029804A1 (en) * 2005-06-27 2007-01-04 Robert Bosch Gmbh Method for adjusting a sheet resistance and a sheet resistance and a strain gauge
CN101692361A (en) * 2009-10-09 2010-04-07 乾坤科技股份有限公司 Resistance device for sensing current
CN103091658A (en) * 2013-02-19 2013-05-08 江苏和利普激光科技有限公司 Current sensor resistance adjusting tool
CN104091664A (en) * 2014-06-12 2014-10-08 北京锋速精密设备有限公司 Novel function curve following resistor trimming method

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110161095A (en) * 2018-02-12 2019-08-23 杭州微策生物技术有限公司 A kind of biosensor resistance adjustment laser system and its method
CN110160563A (en) * 2018-02-12 2019-08-23 杭州微策生物技术有限公司 A kind of method of biosensor resistance adjustment encoded information
CN110160563B (en) * 2018-02-12 2021-03-09 杭州微策生物技术股份有限公司 Method for adjusting coded information by biosensor resistance
CN110161095B (en) * 2018-02-12 2024-02-23 杭州微策生物技术股份有限公司 Biosensor resistance adjustment laser system and method thereof

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