CN105395679A - 用于治疗心绞痛的中药制剂 - Google Patents

用于治疗心绞痛的中药制剂 Download PDF

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CN105395679A
CN105395679A CN201511006736.0A CN201511006736A CN105395679A CN 105395679 A CN105395679 A CN 105395679A CN 201511006736 A CN201511006736 A CN 201511006736A CN 105395679 A CN105395679 A CN 105395679A
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王璐
许璟
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Qingdao Changanda Pharmaceutical Co Ltd
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Abstract

本发明公开了一种用于治疗心绞痛的中药制剂，由以下重量份的中药制剂原料制成：败酱草39-46份，皂矾31-38份，闹羊花21-28份，山豆根15-28份，青礞石13-24份，马宝11-18份，卷柏8-16份，五味子3-9份。本发明具有疗效显著、不易复发、无毒副作用、价格低廉、制备方法简单的优点。

Description

用于治疗心绞痛的中药制剂
技术领域
本发明涉及一种用于治疗心绞痛的中药制剂。
背景技术
心绞痛是指由于冠状动脉粥样硬化狭窄导致冠状动脉供血不足，心肌暂时缺血与缺氧所引起的以心前区疼痛为主要临床表现的一组综合征。心绞痛可能是在缺血缺氧的情况下，心肌内积聚过多的代谢产物，如乳酸、丙酮酸、磷酸等酸性物质；或类似激肽的多肽类物质，刺激心脏内植物神经的传入纤维末梢，经1～5胸交感神经节和相应的脊髓段，传至大脑，产生疼痛感觉。这种痛觉反映在与植物神经进入水平相同脊髓段的脊神经所分布的皮肤区域，即胸骨后及两臂的前两侧与小指，尤其是在左侧，在缺血区内富有神经供应的冠状血管的异常牵拉或收缩，可以直接产生疼痛冲动。典型心绞痛发作是突然发生的位于胸骨体上段或中段之后的压榨性、闷胀性或窄息性疼痛，亦可能波及大部分心前区，可放射至左肩、左上肢前内侧，达无名指和小指，偶可伴有濒死的恐惧感觉，往往迫使病人立即停止活动，重者还出汗。疼痛历时1～5分钟，很少超过15分钟；休息或含有硝酸甘油片，在1～2分钟内(很少超过5分钟)消失。常在体力劳累、情绪激动(发怒、焦急、过度兴奋)、受寒、饱食、吸烟时发生贫血、心动过速或休克亦可诱发。不典型的心绞痛，疼痛可位于胸骨下段、左心前区或上腹部，放射至颈、下颌、左肩胛部或右前胸，疼痛可很快或仅有左前胸不适发闷感。心绞痛目前在我国的发病率呈逐年上升趋势，严重危害着人民群众的健康和生活，本病多见于男性，多数病人在40岁以上，劳累、情绪激动、饱食、受寒、阴雨天气、急性循环衰竭等为常见的诱因，危害不容小觑。目前西医治疗应用硝酸甘油类扩张冠状血管，但会产生毒副作用，容易使患者出现博动性剧烈头痛、头昏、眩晕等症状，且容易复发，见效慢，价格昂贵；而中药制剂学作为我国的传统医学，具有作用强、见效快、药效持久等优点，且没有依赖性、耐药性以及毒副作用，因此选择一种中药制剂制剂治疗心绞痛，对于治疗心绞痛具有十分重要的临床意义。
发明内容
本发明所要解决的技术问题是：提供了一种用于治疗心绞痛的中药制剂。
为解决上述技术问题，本发明采用的技术方案是：
本发明提供的一种用于治疗心绞痛的中药制剂，由以下重量份的中药制剂原料制成：败酱草39-46份，皂矾31-38份，闹羊花21-28份，山豆根15-28份，青礞石13-24份，马宝11-18份，卷柏8-16份，五味子3-9份。
优选的，本发明提供的中药制剂由以下重量份的中药制剂原料制成：败酱草46份，皂矾38份，闹羊花28份，山豆根28份，青礞石24份，马宝18份，卷柏16份，五味子9份。
用法用量：将上述原料用温水浸泡30分钟后，用武火煮沸后再用文火煮30分钟，取药液150毫升，再加水二煎，将两次药液混合后过滤，分两次服用。每天两次，饭后服用。
疗程：15天为一疗程，需服用2-5疗程。
本发明的有益效果：
本发明具有疗效显著、不易复发、无毒副作用、价格低廉、制备方法简单的优点。
下面结合临床实验说明本发明的有益效果：（1）临床资料：本发明共治疗心绞痛患者100例，其中男60例，女40例，年龄为33-58岁。（2）治疗方法：将上述原料用温水浸泡30分钟后，用武火煮沸后再用文火煮30分钟，取药液150毫升，再加水二煎，将两次药液混合后过滤，分两次服用。每天两次，饭后服用。
疗程：15天为一疗程，需服用2-5疗程。（3）疗效评价标准：显效：症状、体征消失；有效：症状、体征有所改善；无效：症状与体征无明显改善。（4）治疗结果：本发明共治疗心绞痛患者100例，经过3-5个疗程的治疗，显效93例，有效6例，无效1例，未见任何副作用。（5）典型病例：1、黄某，女，53岁，患者出现心胸隐痛，伴有胸闷气短，诊断为心绞痛。服用本发明的中药制剂2个疗程好转，3个疗程治愈，随访1年未复发。2、郭某，男，68岁，患者出现阵发性心前区疼痛，胸闷，诊断为心绞痛。服用本发明的中药制剂3个疗程治愈，随访1年未复发。
具体实施方式
实施例1
本实施例提供的一种用于治疗心绞痛的中药制剂，由以下重量份的中药制剂原料制成：败酱草46份，皂矾38份，闹羊花28份，山豆根28份，青礞石24份，马宝18份，卷柏16份，葛根13份。

Claims (2)

1.一种用于治疗心绞痛的中药制剂，其特征在于，由以下重量份的中药制剂原料制成：败酱草39-46份，皂矾31-38份，闹羊花21-28份，山豆根15-28份，青礞石13-24份，马宝11-18份，卷柏8-16份，五味子3-9份。
2.根据权利要求1所述的中药制剂，其特征在于，由以下重量份的中药制剂原料制成：败酱草46份，皂矾38份，闹羊花28份，山豆根28份，青礞石24份，马宝18份，卷柏16份，五味子9份。
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105943687A (zh) * 2016-06-24 2016-09-21 赵晶晶 一种治疗心绞痛的中药自微乳速释滴丸及制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104689223A (zh) * 2013-12-09 2015-06-10 青岛百草汇中草药研究所 一种治疗心绞痛的中药汤剂

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104689223A (zh) * 2013-12-09 2015-06-10 青岛百草汇中草药研究所 一种治疗心绞痛的中药汤剂

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105943687A (zh) * 2016-06-24 2016-09-21 赵晶晶 一种治疗心绞痛的中药自微乳速释滴丸及制备方法

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Application publication date: 20160316