CN105363138B - Electron linear accelerator and the X ray radiotherapy machine of MRI guiding - Google Patents
Electron linear accelerator and the X ray radiotherapy machine of MRI guiding Download PDFInfo
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Abstract
The present invention relates to the radiotherapy machine that a kind of accelerator and MRI are guided, the accelerator is provided with magnetron, magnetron includes tube core and magnet, magnet uses the main magnet of MRI system, tube core is arranged on as caused by main magnet in the main field of MRI system, and magnetic line of force direction of the axis direction of tube core along main field；The radiotherapy machine of the MRI guiding is made up of radiotherapy machine and online MR imaging apparatus, radiotherapy machine, which is provided with, is used for linear accelerator and/or cyclotron that charged particle accelerates, linear accelerator and cyclotron are provided with magnetron, online MR imaging apparatus is provided with the main magnet for being used for forming MRI main fields, the tube core of magnetron is arranged in MRI main fields, the stationary magnetic field of magnetron is served as with MRI main fields, linear accelerator is located at the outside of the main magnet.The accelerator more compact of the present invention, produce more high-power electron beam；Radiotherapy machine is compacter, can quick and precisely deliver line to the irradiation position specified.
Description
Technical field
The present invention relates to the radiotherapy machine that a kind of accelerator and MRI are guided, belong to technical field of medical instruments.
Background technology
Magnetron is the device for producing electromagnetic wave.Its usual tube core is made up of two concentric metal cylinders, center
Cylinder is negative electrode, and outer layer is anode.There is a series of resonant cavity on anode.Sky between these resonant cavities and two cylinders
Chamber communicates and is in vacuum state.Whole cylinder is placed in magnetic field, and magnetic direction is axial along cylinder.When negative electrode is heated
Afterwards, free electron produces near negative electrode.These electronics under the collective effect in electric field and magnetic field along curve from cathode to anode
Motion, is simultaneously emitted by electromagnetic wave.Electromagnetic wave further interacts to form a stable state with electronics.Now, electromagnetic wave
Centre frequency is determined by the shape and yardstick of anode resonant cavity.Electromagnetic wave can be drawn from anode resonant cavity.When straight for electronics
During line accelerator, the electromagnetic wave as driving electromagnetic wave be admitted to electron linear accelerator be used for electronics is accelerated, when with
When cyclotron, the electromagnetic wave can be used for being formed the high frequency of the driving charged particle such as proton or heavy ion among D flasks
Electric field.
What usually magnetron tube core provided magnetic field is one piece of permanent magnet, and high power magnetic keyholed back plate can use electromagnet, its magnetic
Field intensity reaches as high as several kilogauss, correspondingly, as caused by magnetron the highest frequency of electromagnetic wave in other words minimal wave length with
And power output is than relatively limited, accordingly, due to the distance and the ripple of driving electromagnetic wave of the adjacent cavities of electron linear accelerator
Length is directly proportional, therefore the physical dimension of existing electron linear accelerator is minimized also just by the shadow of the above-mentioned limitation of magnetron
Ring.Because the electron linear accelerator scale of construction is bigger than normal, it is unfavorable for automation manipulation, therefore operating efficiency, positioning accuracy to it
Deng being easily affected, have much room for improvement.
The radiotherapy of malignant tumour is the treatment line by doses with radiotherapy machine（Such as X-ray or electron beam）
Therapy area is shipped to prevent the growth of cancer cell.X-ray is that caused on tungsten target, high energy electricity is got to by high energy electron
Son is as caused by electron linear accelerator.Driving electromagnetic wave enters from the radio frequency window of electron linear accelerator caused by magnetron
Enter accelerator cavity, electromagnetic wave forms standing wave or traveling wave in cavity.It is electric caused by electron gun positioned at accelerator cavity one end
Beamlet initial voltage effect to another end motion.If electron motion is synchronous with driving electromagnetic wave, electronics is from electromagnetic field
Obtain energy, speed increase, i.e., described high energy electron.Equally, radiation can also be carried out using proton beam, HIB etc. to control
Treat.
In the radiotherapy research and development laboratory prototype of existing MRI guiding few in number, designed by Canadian Alberta universities
System rotates excessively heavy magnet, brings no small difficulty to Machine Design, the stability and reliability to system cause newly
The problem of.
In the MRI guiding radiotherapy laboratory systems that Elekta companies are researched and developed, treatment ray need to penetrate liquid helium groove, gradient
Coil and radio-frequency coil, so as to cause the change of the hardening effect for the treatment of X-ray and power spectrum, to treatment impact, it is necessary to
Improve the high pressure and beam intensity of accelerator.
The laboratory system in Sydney uses the design of rotating patient and therapeutic bed, due to the deformation of human body soft tissue, to swollen
The bigger difficulty that the positioning of knurl and track band come, and because the fitness problem of patient, many situations are not suitable for rotation
Patient, rotation patient belong to the inadequate hommization of patient.
It can be seen that track and localization when the inadequate compact of radiotherapy machine generally existing moving part of existing MRI guiding, treatment
The operation technical problem that precision is not high and accelerator intensity is not high.
The content of the invention
In order to overcome the drawbacks described above under prior art, it is an object of the invention to provide a kind of accelerator and MRI to guide
Radiotherapy machine, the accelerator more compact；The radiotherapy machine structure of the MRI guiding is compacter, can quickly, accurately
Line is delivered to the irradiation position specified.
The technical scheme is that：
A kind of accelerator, provided with magnetron, the magnetron includes tube core and magnet, and the magnet is using MRI system
Main magnet, the tube core are arranged on as caused by the main magnet in the main field of the MRI system, and the axis of the tube core
Magnetic line of force direction of the direction along the main field.
The accelerator is linear accelerator or cyclotron, and the linear accelerator, which is provided with, is used for charged particle（Example
Such as electronics, proton, heavy ion, similarly hereinafter）The accelerating tube of acceleration, the cyclotron, which is provided with, is used for the D that charged particle accelerates
Flask, the main magnet of the MRI system preferably use superconducting coil, and the cyclotron D flasks are also disposed at the MRI systems
In the main field of system.
The main magnet can be flat main magnet or drum type brake main magnet, and the flat main magnet includes parallel phase
To two magnetic poles of setting, the magnetic field between two magnetic poles forms the main field；The drum type brake main magnet is in cylinder
Shape, the magnetic field in its axial bore is the main field.
When the main magnet is drum type brake main magnet, the axis weight of the axis of the tube core preferably with the main magnet
Close.
A kind of radiotherapy machine of MRI guiding, is mainly made up of, the radiotherapy machine is set radiotherapy machine and online MR imaging apparatus
There is the linear accelerator accelerated for charged particle（Also referred to as electron linear accelerator）And/or cyclotron, the straight line add
Fast device and cyclotron are provided with magnetron, and the online MR imaging apparatus is provided with the main magnetic for being used for forming MRI main fields
Body, it is characterised in that the tube core of the magnetron is arranged in the MRI main fields, and the magnetic is served as with the MRI main fields
The stationary magnetic field of keyholed back plate, the electron linear accelerator are located at the outside of the main magnet.
The main magnet preferably uses superconducting coil.
The main magnet can be flat main magnet or drum type brake main magnet, and the flat main magnet includes parallel phase
To two magnetic poles of setting, the magnetic field between two magnetic poles forms the main field；The drum type brake main magnet is in cylinder
Shape, the magnetic field in its axial bore is the main field.
The main magnet is provided with the therapeutic window passed through for treatment line, when the main magnet is flat main magnet
When, the therapeutic window can use the combination of any one following structural shape or two kinds of structural shapes：
（1）The region that any pair corresponding of edge of two magnetic poles is limited forms the therapeutic window；
（2）Any one or two magnetic poles are provided with opening, and the opening forms the therapeutic window.
When the main magnet is drum type brake main magnet, the therapeutic window can use any one following structural shape：
（1）The either end of the main magnet axial direction is open to form the therapeutic window；
（2）The main magnet is integral type structure, which is provided with radial aperture, and the radial aperture forms the treatment
Window；Or the main magnet is split-type structural, including axially arranged forward and backward two parts, between described forward and backward two parts
Leave gap, the surface annular region between described forward and backward two parts forms the therapeutic window.
For the flat main magnet, the space between two magnetic poles is imaging area for treatment, and therapeutic bed passes in and out
The region that mouth is limited by any pair corresponding of edge of two magnetic poles；For the drum type brake main magnet, when described
Therapeutic window uses said structure pattern（1）When, the main magnet is split-type structural, including axially arranged forward and backward two parts,
Gap is left between described forward and backward two parts, the gap forms the placement location of therapeutic bed and the therapeutic bed in treatment and entered
Go out the passage of the main field；When the therapeutic window uses said structure pattern（2）When, therapeutic bed inlet and outlet are the main magnet
The either end of axial direction is open.
For the flat main magnet, when the therapeutic window uses structural shape（1）When, the therapeutic bed inlet and outlet,
The therapeutic window and the tube core position correspond to the corresponding paired edge of two different magnetic poles and limited respectively
Region；For the drum type brake main magnet, when the therapeutic window uses said structure pattern（1）When, the therapeutic window and institute
State the open at both ends that tube core position corresponds to the main magnet axial direction respectively；When the therapeutic window uses said structure pattern
（2）When, the therapeutic bed inlet and outlet and the tube core position correspond to the axial open at both ends of the main magnet respectively.
For the drum type brake main magnet, the axis of the axis of the tube core preferably with the main magnet overlaps.
The radiotherapy machine can be electron beam radiotherapy machine, X ray radiotherapy machine, proton radiotherapy machine or heavy ion radiotherapy machine, when
When the radiotherapy machine is electron beam radiotherapy machine or X ray radiotherapy machine, the accelerator is electron linear accelerator, and the electronics is straight
Line accelerator is one or more, and each electron linear accelerator, which is arranged on one, to be had on multivariant mechanical arm,
When the radiotherapy machine is proton radiotherapy machine or heavy ion radiotherapy machine, the accelerator is cyclotron, and the convolution accelerates
The D flasks of device are arranged in the main field of the MRI system.
Beneficial effects of the present invention are：
Magnetron tube core is placed in the main magnet of MRI system by the present invention, i.e. the main field of magnetron and MRI system shares
Magnet so that magnetron is compacter in the application scenario structure provided with MRI system, also enables the tube core of magnetron to be operated in
In stronger magnetic field, so as to produce output higher frequency, more high-output power electromagnetic wave.
The D flasks of cyclotron are placed in the main magnet of MRI system by the present invention, are served as with the main field of MRI system
It is used to make the uniform magnetic field that charged particle moves in a circle in cyclotron, i.e. the main field of D flasks and MRI system shares magnetic
Body so that cyclotron can be accomplished smaller in the application scenario radius of gyration provided with MRI system, and structure is compacter, together
When magnetron is arranged on to the main field of MRI system, form the electromagnetic wave of higher frequency, generated with this and be used to accelerate matter on D flasks
The alternating electric field of the charged particles such as son, further to improve radiotherapeutic effect.
Because the main magnet of the MRI system uses superconducting magnet, the magnetic field intensity that superconducting magnet produces cryogenic magnetic field can
To reach tens of thousands of Gausses, therefore the magnetron turns into high-frequency, short wavelength, the electromagnetic wave driving source of high-power output.
Also therefore, make the adjacent cavities distance of electron linear accelerator smaller, so that the structure of electron linear accelerator is compacter,
Further expand the application field and the scope of application of electron linear accelerator.Such as the magnetron is combined with X-band accelerating tube,
Overall compact, high intensity X source can be obtained, such light source is advantageous to the manipulation of robot, during so as to shorten treatment
Between, reduce treatment cost.
The radiotherapy machine of the MRI guiding of the present invention makes magnetron share main magnet with MRI system（Using superconducting magnet）, utilize
MRI high-intensity magnetic field, significantly increase magnetron power output.Particularly in X-band, while also reduce whole radiotherapy machine
Size simultaneously reduces cost.Due to being operated in the electron linear accelerator compact of X-band, magnetron output is shorter in addition
The electromagnetic wave of wavelength is advantageous to further reduce the size of electron linear accelerator so that the electronic line of sight as x-ray source adds
Fast device is easier to be manipulated by robot so that radiotherapy machine of the present invention can quickly, precise delivery line
To the irradiation position specified, treatment time is further shorten, reduces treatment cost, also helps the more treatment work(of increase
Can, therefore possess stronger treatment ability of medicine.
Due to that there is provided online MR imaging apparatus, magnetic resonance imaging can be carried out in radiotherapy, with magnetic resonance imaging
Based on carry out radiation guiding, thus given full play to MRI display tumor target and around the high-resolution of sensitive organization, height
Contrast and the ability of dynamic tracking target area motion, while avoid because of X-ray scanning and be imaged and give patient's normal structure band
The additional injuries come, and use robot to drive electron linear accelerator motion, being capable of multi-angle, non-coplanar multi-faceted high-precision
Control therapy apparatus in degree ground realizes the positioning and treatment to focus target area, and the electron linear accelerator on robot top can be in strong magnetic
Quick, precise delivery radiotherapy line to the irradiation position specified under the environment of field, so that radiotherapy machine is with more to patient
Treat function, stronger treatment ability of medicine and more preferable therapeutic effect, due to the smaller dose of radiation to nonneoplastic tissue and
The more accurately definition to tumor target, thus there is more preferable biological effect, be advantageous to promote radiotherapy technology to enter newly
Epoch.
Brief description of the drawings
Fig. 1 is the structural representation of the embodiment one of the radiotherapy machine of the MRI guiding of the present invention；
Fig. 2 is the structural representation of the embodiment two of the radiotherapy machine of the MRI guiding of the present invention；
Fig. 3 is the structural representation of the embodiment three of the radiotherapy machine of the MRI guiding of the present invention；
Fig. 4 is the structural representation of the example IV of the radiotherapy machine of the MRI guiding of the present invention；
Fig. 5 is the structural representation of the embodiment five of the radiotherapy machine of the MRI guiding of the present invention；
Fig. 6 is the structural representation of the embodiment six of the radiotherapy machine of the MRI guiding of the present invention.
Embodiment
The invention provides a kind of accelerator, and provided with magnetron, the magnetron includes tube core and magnet, and the magnet is adopted
Use MRI（Magnetic Resonance Imaging, magnetic resonance imaging）The main magnet of system, the tube core are arranged on by described
Caused by main magnet in the main field of the MRI system, and the magnetic line of force of the axis direction of the tube core along the main field
Direction.
The accelerator is linear accelerator or cyclotron, and the linear accelerator, which is provided with, is used for charged particle acceleration
Accelerating tube, the cyclotron, which is provided with, is used for the D flasks that charged particle accelerates, and the main magnet of the MRI system is using super
Loop, the cyclotron D flasks are also disposed in the main field of the MRI system.
The MRI system includes being used to produce the main field of magnetic field of high uniformity and for producing and controlling main field
The gradient magnetic of magnetic field gradient, correspondingly, main field is formed using main magnet, and gradient magnetic is produced using three groups of coils, respectively
Produce the gradient fields in three directions of x, y, z.The main field refers both to physically be limited caused by main magnet, positioned at main magnet
Magnetic field within space.
The magnetic field intensity of cryogenic magnetic field is produced due to superconducting magnet can reach tens of thousands of Gausses, be higher by existing magnetron
Magnet an order of magnitude, therefore can make the electromagnetic wave of magnetron output that there is higher frequency, shorter wavelength, higher
Power.It is possible thereby to the driving electromagnetic wave of higher energy is provided for accelerator.
When magnetron or its accelerator being used for are used in MRI system, the magnetron using the present invention can make equipment whole
Body structure is compacter, is also beneficial to reduce the cost of whole equipment system.
The main magnet can be flat main magnet or drum type brake main magnet, and the flat main magnet includes parallel phase
To two magnetic poles of setting, the magnetic field between two magnetic poles forms the main field；The drum type brake main magnet is in cylinder
Shape, the magnetic field in its axial bore is the main field.
When the main magnet is drum type brake main magnet, the axis of the tube core can be with the axis weight of the main magnet
Close, make the magnetic force more uniformity being subject to everywhere in the tube core.
Because magnetron of the present invention can export shorter wavelengths of electromagnetic wave, particularly with being operated in PI- patterns
Accelerator, because wavelength is shorter, the distance of adjacent cavities is smaller in accelerator, thus the present invention electron linear accelerator knot
Structure is compacter, further expands the application field and the scope of application of electron linear accelerator.Such as the magnetron and X ripples
Section accelerating tube combines, and can obtain overall compact, high intensity X source, and such light source is advantageous to the manipulation of robot,
Contribute to shorten treatment time in MRI system, reduce treatment cost.
As shown in figures 1 to 6, present invention also offers a kind of radiotherapy machine of MRI guiding, mainly it is total to by radiotherapy machine and online magnetic
The imaging device that shakes form, the radiotherapy machine be provided be used for charged particle accelerate accelerator, including linear accelerator 10 and/or return
Accelerator 90 is revolved, the accelerator is connected by waveguide 80 with the tube core 60 of a magnetron, and the online magnetic resonance imaging is set
Standby to be provided with the main magnet for being used for forming MRI main fields, the tube core of the magnetron is arranged in the MRI main fields, with described
MRI main fields serve as the stationary magnetic field of the magnetron, and the linear accelerator is located at the outside of the main magnet.
The online MR imaging apparatus is provided with the main magnet for being used for forming main field, and the main magnet uses superconducting line
Circle.
The main magnet is flat main magnet or drum type brake main magnet, and the flat main magnet is set relatively including parallel
Two magnetic poles put, the magnetic field between two magnetic poles form the main field；The cylindrical shape of drum type brake main magnet,
Magnetic field in its axial bore is the main field.
The main magnet is provided with the therapeutic window 70 passed through for treatment line.
Magnetron tube core is placed in uniform magnetic field caused by the superconducting coil of magnetic resonance imaging system, produces electromagnetic wave.
Electromagnetic wave enters in the accelerating tube of electron linear accelerator after the anode resonant cavity of magnetron is drawn through the waveguide, right
Electronics accelerates.Electronics after acceleration, which is got on rotation tungsten target, can produce X ray.For treatment line（Electronics or X ray）It is logical
The therapy area set by treatment plan that the therapeutic window is injected in main field is crossed, thus, radiation is carried out to lesions position and controlled
Treat.
The electron linear accelerator is arranged on the mechanical arm of robot, and its motion is driven by the robot（Change
Position and/or direction）.The direction and position of the relatively described therapeutic window of the electron linear accelerator are adjusted, line is delivered
To therapy area.
Preferably, the robot uses the series connection mechanical arm 21 with 6 frees degree, the electron linear accelerator peace
Mounted in the top of the series connection mechanical arm, so that the electron linear accelerator is in required optional position and any angle.
Preferably, the robot is additionally provided with walking mechanism, and the walking mechanism includes being used to install the series connection machinery
The robot base 22 of arm and the robot ambulation wheel 23 below the robot base, in addition to for driving machine
The hoofing part mechanism of people's road wheel motion, thus, it is possible to by the stabilized walking of walking mechanism control machine people, makes electronics straight
Line accelerator is in effective or optimum position.
Optionally, the track supporting with the robot ambulation wheel is surrounded with around the online MR imaging apparatus,
Thus allow the robot to surround online MR imaging apparatus.
The electron linear accelerator preferably uses the accelerating tube of X-band, structure more compact, is advantageous to robot
Manipulation.
The online MR imaging apparatus is provided with base 35 and the support 34 on base, and two magnetic pole is pacified
Dress is on the bracket.
The online MR imaging apparatus is also equipped with corresponding therapeutic bed 50, to facilitate the transfer of patient.
When using cyclotron, electromagnetic wave that the magnetron is drawn is through D types that waveguide 80 is cyclotron
Box provides radio-frequency driven power, to form high-frequency electric field.The charged particle beam of D flasks output is exported by charged particle passage 100,
The therapy area set by treatment plan injected through the therapeutic window in main field, thus, carries out radiation to lesions position and controls
Treat.
The main magnet can be flat main magnet 30（Referring to Fig. 1,2）Or drum type brake main magnet 40（Referring to Fig. 3,4,
5、6）.
The flat main magnet can include two magnetic poles 31,32 for being oppositely arranged in parallel, between two magnetic poles
Space 33 be the main field region, while be also imaging area for treatment.One can be provided between two magnetic poles
Individual or multiple support posts 38.
The therapeutic window can use the combination of any one following structural shape or two kinds of structural shapes：
（1）The region that any pair corresponding of edge of two magnetic poles is limited（When two magnetic poles are corresponding
A pair of sides aligned parallels set when, the region is plane domain, similarly hereinafter）Form the therapeutic window（Referring to Fig. 1）；
（2）Any one or two magnetic poles are provided with opening 70, and the opening forms the therapeutic window（Referring to figure
2）.
Patient is sent to the imaging area for treatment, the treatment of the therapeutic bed disengaging imaging area for treatment by therapeutic bed
The region that bed inlet and outlet are limited by any pair corresponding of edge of two magnetic poles.By taking rectangular flat magnetic pole as an example, magnetic
The each edge of pole can correspond to a therapeutic bed inlet and outlet, specifically set which or which therapeutic bed to import and export depending on entirely setting
Standby system has structure determination.
When the therapeutic window uses structural shape（1）When, therapeutic bed inlet and outlet, the therapeutic window and the tube core institute
Preferably correspond to the region that the corresponding paired edge of two different magnetic poles is limited respectively in position；To avoid institute as far as possible
When stating therapeutic bed or the electron linear accelerator and moving, interfered with other both.
The cylindrical shape of drum type brake main magnet, be centered around one closing cylinder in by helically coiled into magnetic
Body, its axial bore 42 are the main field region, while are also imaging area for treatment.The therapeutic window can use down
Arrange any one structural shape：
（1）The either end of the main magnet axial direction is open to form the therapeutic window 70（Referring to Fig. 3）；
（2）The main magnet is integral type structure, which is provided with radial aperture, and the radial aperture forms the therapeutic window
（Referring to Fig. 4）；Or the main magnet is split-type structural, including axially arranged forward and backward two parts, described forward and backward two
/ leaving gap, the surface annular region between described forward and backward two parts forms the therapeutic window（Referring to Fig. 5）.
When the therapeutic window uses said structure pattern（1）When, the main magnet is split-type structural, including axially arranged
Forward and backward two parts 43,44, gap is left between described forward and backward two parts, the gap forms the placement of therapeutic bed in treatment
Position and the therapeutic bed pass in and out the passage of the main field.The therapeutic window and the tube core position preferably correspond to respectively
The open at both ends of the main magnet axial direction.
When the therapeutic window uses said structure pattern（2）When, therapeutic bed inlet and outlet are any for main magnet axial direction
Open at one end.The both ends that the therapeutic bed inlet and outlet and the tube core position preferably correspond to the main magnet axial direction respectively open
Mouthful.
For the drum type brake main magnet, the axis of the axis of the tube core preferably with the main magnet overlaps.
The radiotherapy machine is electron beam radiotherapy machine, X ray radiotherapy machine, proton radiotherapy machine or heavy ion radiotherapy machine, when described
When radiotherapy machine is electron beam radiotherapy machine or X ray radiotherapy machine, the accelerator is electron linear accelerator, and the electronic line of sight adds
Fast device is one or more, and each electron linear accelerator, which is arranged on one, to be had on multivariant mechanical arm, works as institute
When to state radiotherapy machine be proton radiotherapy machine or heavy ion radiotherapy machine, the accelerator is cyclotron, the D of the cyclotron
Flask is arranged in the main field of the MRI system, and magnetic line of force direction of the centerline direction of D flasks along main field, excellent
Choosing overlaps with the magnetic line of force of main field.
Below by taking the X ray radiotherapy machine based on electron linear accelerator as an example, treatment comprises the following steps that：
1st, place the patient into the magnetic field formed for the online magnetic resonance imaging main magnet of radiotherapy in the treatment target area tracking；
2nd, MRI, which is imaged and adjusts patient location, makes therapy area towards X ray incidence window（That is therapeutic window）；
3rd, according to treatment plan, manipulated by robot, x-ray source is in the side that its X ray will be shipped to therapy area
On position.Set according to treatment plan/adjust electron energy；
4th, set/adjust electron gun line to change with time according to treatment plan；
5th, set/adjust X ray incoming position and angle according to treatment plan；
6th, set according to treatment plan/adjust vane grating（Control adjustment assembling is not drawn into）；
7th, start electron linear accelerator to start to treat；
8th, the motion of tracking target area is implemented in MRI imagings；
9th, repeat step 3-8 is until treatment plan completion.
Claims (10)
1. a kind of accelerator, provided with magnetron, it is characterised in that the magnetron includes tube core and magnet, and the magnet uses
The main magnet of MRI system, the tube core are arranged on as caused by the main magnet in the main field of the MRI system, and described
Magnetic line of force direction of the axis direction of tube core along the main field.
2. accelerator as claimed in claim 1, it is characterised in that the accelerator is linear accelerator or cyclotron, institute
State linear accelerator and be provided with and be used for the accelerating tube that charged particle accelerates, the cyclotron, which is provided with, is used for what charged particle accelerated
D flasks, the main magnet of the MRI system use superconducting coil, and the cyclotron D flasks are also disposed at the MRI system
Main field in.
3. accelerator as claimed in claim 2, it is characterised in that the main magnet is flat main magnet or the main magnetic of drum type brake
Body, the flat main magnet include two magnetic poles being oppositely arranged in parallel, described in the magnetic field between two magnetic poles is formed
Main field；The cylindrical shape of drum type brake main magnet, the magnetic field in its axial bore is the main field.
4. a kind of radiotherapy machine of MRI guiding, is mainly made up of, the radiotherapy machine is provided with radiotherapy machine and online MR imaging apparatus
The linear accelerator and/or cyclotron accelerated for charged particle, the linear accelerator and cyclotron are provided with magnetic
Keyholed back plate, the online MR imaging apparatus are provided with the main magnet for being used for forming MRI main fields, it is characterised in that the magnetron
Tube core be arranged in the MRI main fields, the stationary magnetic field of the magnetron, the straight line are served as with the MRI main fields
Accelerator is located at the outside of the main magnet.
5. the radiotherapy machine of MRI guiding as claimed in claim 4, it is characterised in that the main magnet uses superconducting coil.
6. the radiotherapy machine of MRI guiding as claimed in claim 5, it is characterised in that the main magnet is flat main magnet or circle
Cartridge type main magnet, the flat main magnet include two magnetic poles being oppositely arranged in parallel, the magnetic field between two magnetic poles
Form the main field；The cylindrical shape of drum type brake main magnet, the magnetic field in its axial bore is the main field.
7. the radiotherapy machine of MRI guiding as claimed in claim 6, it is characterised in that the main magnet is provided with for treatment line
The therapeutic window passed through, when the main magnet is flat main magnet, the therapeutic window uses any one following structural shape
Or the combination of two kinds of structural shapes：
The region that (1) two any pair corresponding of edge of the magnetic pole is limited forms the therapeutic window；
(2) any one or two magnetic poles are provided with opening, and the opening forms the therapeutic window；
When the main magnet is drum type brake main magnet, the therapeutic window uses any one following structural shape：
(1) either end of the main magnet axial direction is open forms the therapeutic window；
(2) main magnet is integral type structure, which is provided with radial aperture, and the radial aperture forms the therapeutic window；Or
Person, the main magnet are split-type structural, including axially arranged forward and backward two parts, between being left between described forward and backward two parts
Gap, the surface annular region between described forward and backward two parts form the therapeutic window.
8. the radiotherapy machine of MRI guiding as claimed in claim 7, it is characterised in that for the flat main magnet, two institutes
It is imaging area for treatment to state the space between magnetic pole, and therapeutic bed inlet and outlet are any pair corresponding of edge of two magnetic poles
The region limited；For the drum type brake main magnet, when the therapeutic window uses said structure pattern（1）When, the main magnetic
Body is split-type structural, including axially arranged forward and backward two parts, and gap, the gap are left between described forward and backward two parts
Form the passage that the placement location of therapeutic bed and the therapeutic bed in treatment pass in and out the main field；When the therapeutic window is using upper
State structural shape（2）When, therapeutic bed inlet and outlet are open for the either end of main magnet axial direction.
9. the radiotherapy machine of MRI guiding as claimed in claim 8, it is characterised in that for the flat main magnet, when described
Therapeutic window uses structural shape（1）When, therapeutic bed inlet and outlet, the therapeutic window and the tube core position correspond to respectively
The region that the corresponding paired edge of two different magnetic poles is limited；For the drum type brake main magnet, controlled when described
Treat window and use said structure pattern（1）When, the therapeutic window and the tube core position correspond to the main magnet axial direction respectively
Open at both ends；When the therapeutic window uses said structure pattern（2）When, the therapeutic bed inlet and outlet and tube core institute are in place
Put the open at both ends for corresponding to the main magnet axial direction respectively.
10. the radiotherapy machine of MRI guiding as claimed in claim 9, it is characterised in that the radiotherapy machine is electron beam radiotherapy machine, X
Ray radiotherapy machine, proton radiotherapy machine or heavy ion radiotherapy machine, when the radiotherapy machine is electron beam radiotherapy machine or X ray radiotherapy machine
When, the accelerator is electron linear accelerator, and the electron linear accelerator is one or more, each electronic line of sight
Accelerator, which is arranged on one, to be had on multivariant mechanical arm, when the radiotherapy machine is proton radiotherapy machine or heavy ion radiotherapy machine
When, the accelerator is cyclotron, and the D flasks of the cyclotron are arranged in the main field of the MRI system.
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| JP6637216B2 (en) | 2016-07-14 | 2020-01-29 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | Magnetic resonance imaging guided treatment system |
| CN110152202A (en) * | 2018-02-01 | 2019-08-23 | 青岛大学附属医院 | A kind of clinical therapy of tumor equipment and its application method |
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| CN102245264A (en) * | 2008-12-12 | 2011-11-16 | 皇家飞利浦电子股份有限公司 | Therapeutic apparatus |
| CN205411948U (en) * | 2015-12-07 | 2016-08-03 | 北京健联医疗科技有限公司 | Radiotherapy machine of accelerator and MRI guide |
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| CN102245264A (en) * | 2008-12-12 | 2011-11-16 | 皇家飞利浦电子股份有限公司 | Therapeutic apparatus |
| CN205411948U (en) * | 2015-12-07 | 2016-08-03 | 北京健联医疗科技有限公司 | Radiotherapy machine of accelerator and MRI guide |
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