CN105363138A - Electron linear accelerator and MRI(magnetic resonance imaging)-guided X-ray radiotherapy machine - Google Patents
Electron linear accelerator and MRI(magnetic resonance imaging)-guided X-ray radiotherapy machine Download PDFInfo
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- CN105363138A CN105363138A CN201510887023.3A CN201510887023A CN105363138A CN 105363138 A CN105363138 A CN 105363138A CN 201510887023 A CN201510887023 A CN 201510887023A CN 105363138 A CN105363138 A CN 105363138A
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Abstract
The invention relates to an accelerator and an MRI(magnetic resonance imaging)-guided X-ray radiotherapy machine. The accelerator is provided with a magnetron, the magnetron comprises a tube core and a magnet, the magnet employs a master magnet of an MRI system, the tube core is arranged in a main magnetic field, generated by the main magnet, of the MRI system, the axial direction of the tube core is along the direction of the magnetic line of the main magnetic field; and the MRI-guided radiotherapy machine is composed of a radiotherapy machine and an online MRI device, the radiotherapy machine is provided with a linear accelerator and/or a cyclotron for acceleration of charged particles, the linear accelerator and the cyclotron are provided with a magnetron, the online MRI device is provided with a main magnet for forming an MRI main magnetic field, the tube core of the magnetron is arranged in the MRI main magnetic field, the MRI main magnetic field is taken as a constant magnetic field of the magnetron, and the linear accelerator is disposed outside the main magnet. The accelerator provided by the invention is smaller and more compact and generates higher-energy electron beams; and the radiotherapy machine is more compact and can rapidly and accurately deliver the beams to specific irradiation positions.
Description
Technical field
The present invention relates to the radiotherapy machine of a kind of accelerator and MRI guiding, belong to technical field of medical instruments.
Background technology
Magnetron is for generation of electromagnetic device.Usually its tube core is made up of two concentric metal cylinders, and center column is negative electrode, and skin is anode.Anode has a series of resonant cavity.Cavity between these resonant cavities with two cylinders communicates and is in vacuum state.Whole cylinder is placed in magnetic field, magnetic direction along cylinder axis to.After negative electrode is heated, free electron produces near negative electrode.These electronics move along curve from negative electrode anode under the combined effect of Electric and magnetic fields, send electromagnetic wave simultaneously.Electromagnetic wave and electronics interact formation steady statue further.Now, electromagnetic mid frequency is determined by the shape of anode resonant cavity and yardstick.Electromagnetic wave can be drawn from anode resonant cavity.When for electron linear accelerator, this electromagnetic wave is admitted to electron linear accelerator for accelerating electronics as driving electromagnetic wave, when for cyclotron, this electromagnetic wave may be used for forming the high-frequency electric field driving the charged particle such as proton or heavy ion in the middle of D flask.
What be generally that magnetron tube core provides magnetic field is one piece of permanent magnet, high power magnetic keyholed back plate can adopt electromagnet, its magnetic field intensity reaches as high as a few kilogauss, correspondingly, the electromagnetic highest frequency produced by magnetron in other words minimal wave length and output more limited, correspondingly, because the distance of the adjacent cavities of electron linear accelerator is directly proportional to the electromagnetic wavelength of driving, therefore the physical dimension miniaturization of existing electron linear accelerator is also just subject to the above-mentioned circumscribed impact of magnetron.Because the electron linear accelerator scale of construction is bigger than normal, be unfavorable for that automatization manipulates, therefore its operating efficiency, Position location accuracy etc. be easily affected, have much room for improvement.
The radiotherapy of malignant tumor is, with radiotherapy machine, the treatment line (as X-ray or electron beam) of doses is shipped to therapy area to stop the growth of cancerous cell.X-ray is got on tungsten target by high energy electron and is produced, and high energy electron is produced by electron linear accelerator.The driving electromagnetic wave that magnetron produces enters accelerator cavity from the radio frequency window of electron linear accelerator, and electromagnetic wave forms standing wave or row ripple in cavity.The electron beam that the electron gun being positioned at accelerator cavity one end produces moves to the other end in the effect of initial voltage.If electron motion is synchronous with driving electromagnetic wave, then electronics obtains energy from electromagnetic field, and speed increases, i.e. described high energy electron.Equally, proton beam, HIB etc. also can be utilized to carry out radiotherapy.
In the radiotherapy research and development laboratory prototype that existing MRI few in number guides, the system designed by Canadian Alberta university rotates too heavy magnet, brings no small difficulty, cause new problem to the stability of system and reliability to Machine Design.
The MRI researched and developed in Elekta company guides in radiotherapy laboratory system, treatment ray need penetrate liquid helium groove, gradient coil and radio-frequency coil, thus cause the hardening effect for the treatment of X-ray and the change of power spectrum, treatment is impacted, needs the high pressure and the beam intensity that improve accelerator.
The laboratory system in Sydney adopts the design of rotating patient and therapeutic bed, due to the distortion of human body soft tissue, to the larger difficulty that the location of tumor and tracking are brought, and due to the body constitution problem of patient, a lot of situation is not suitable for rotating patient, rotates patient and belongs to the inadequate hommization of patient.
Visible, the technical problem that when the inadequate compact of radiotherapy machine ubiquity moving part that existing MRI guides, treatment, track and localization operation precision is not high and accelerator intensity is not high.
Summary of the invention
In order to overcome the above-mentioned defect under prior art, the object of the present invention is to provide the radiotherapy machine that a kind of accelerator and MRI guide, described accelerator compact more; The radiotherapy machine structure that described MRI guides is compacter, can fast, precise delivery line is to the irradiation position of specifying.
Technical scheme of the present invention is:
A kind of accelerator, be provided with magnetron, described magnetron comprises tube core and magnet, and described magnet adopts the main magnet of MRI system, described tube core is arranged in the main field of the described MRI system produced by described main magnet, and the axis direction of described tube core is along the magnetic line of force direction of described main field.
Described accelerator is linear accelerator or cyclotron, described linear accelerator is provided with for charged particle (such as electronics, proton, heavy ion etc., the accelerating tube accelerated down together), described cyclotron is provided with the D flask accelerated for charged particle, the main magnet of described MRI system preferably adopts superconducting coil, and described cyclotron D flask is also arranged in the main field of described MRI system.
Described main magnet can be flat main magnet or the main magnet of drum type brake, and described flat main magnet comprises parallel two magnetic poles be oppositely arranged, and the magnetic field between two described magnetic poles forms described main field; The cylindrical shape of the main magnet of described drum type brake, the magnetic field in its axial bore is described main field.
When described main magnet is the main magnet of drum type brake, the axis of described tube core preferably with the dead in line of described main magnet.
The radiotherapy machine that a kind of MRI guides, form primarily of radiotherapy machine and online MR imaging apparatus, described radiotherapy machine is provided with the linear accelerator (also claiming electron linear accelerator) and/or cyclotron that accelerate for charged particle, described linear accelerator and cyclotron are provided with magnetron, described online MR imaging apparatus is provided with the main magnet for the formation of MRI main field, it is characterized in that the tube core of described magnetron is arranged in described MRI main field, the stationary magnetic field of described magnetron is served as with described MRI main field, described electron linear accelerator is positioned at the outside of described main magnet.
Described main magnet preferably adopts superconducting coil.
Described main magnet can be flat main magnet or the main magnet of drum type brake, and described flat main magnet comprises parallel two magnetic poles be oppositely arranged, and the magnetic field between two described magnetic poles forms described main field; The cylindrical shape of the main magnet of described drum type brake, the magnetic field in its axial bore is described main field.
Described main magnet is provided with the treatment window passed through for treatment line, and when described main magnet is flat main magnet, described treatment window can adopt the combination of any one structural shape following or two kinds of structural shapes:
The region that corresponding any pair edge of (1) two described magnetic pole limits forms described treatment window;
(2) any one or two described magnetic poles are provided with opening, and described opening forms described treatment window.
When described main magnet is the main magnet of drum type brake, described treatment window can adopt any one structural shape following:
(1) any open at one end of described main magnet axial forms described treatment window;
(2) described main magnet is integral type structure, which is provided with radial aperture, and described radial aperture forms described treatment window; Or described main magnet is split-type structural, comprise the forward and backward two parts axially arranged, leave gap between described forward and backward two parts, the surperficial annular region between described forward and backward two parts forms described treatment window.
For described flat main magnet, the space between two described magnetic poles is imaging area for treatment, and therapeutic bed imports and exports the region for any pair edge that two described magnetic poles are corresponding limits; For the main magnet of described drum type brake, when described treatment window adopts said structure pattern (1), described main magnet is split-type structural, comprise the forward and backward two parts axially arranged, leave gap between described forward and backward two parts, described gap forms the passage that the placement location of therapeutic bed in treatment and described therapeutic bed pass in and out described main field; When described treatment window adopts said structure pattern (2), therapeutic bed imports and exports any open at one end for described main magnet axial.
For described flat main magnet, when described treatment window adopts structural shape (1), described therapeutic bed import and export, described treatment window and the region becoming edge to limit that corresponding two different described magnetic poles are corresponding respectively, described tube core position; For the main magnet of described drum type brake, when described treatment window adopts said structure pattern (1), the open at both ends of described treatment window and the corresponding described main magnet axial of described tube core position difference; When described treatment window adopts said structure pattern (2), the open at both ends of described therapeutic bed import and export and the corresponding described main magnet axial of described tube core position difference.
For the main magnet of described drum type brake, the axis of described tube core preferably with the dead in line of described main magnet.
Described radiotherapy machine can be electron beam radiotherapy machine, X-ray radiotherapy machine, proton radiotherapy machine or heavy ion radiotherapy machine, when described radiotherapy machine be electron beam radiotherapy machine or X-ray radiotherapy machine time, described accelerator is electron linear accelerator, described electron linear accelerator is one or more, each described electron linear accelerator is arranged on one and has on multivariant mechanical arm, when described radiotherapy machine be proton radiotherapy machine or heavy ion radiotherapy machine time, described accelerator is cyclotron, and the D flask of described cyclotron is arranged in the main field of described MRI system.
Beneficial effect of the present invention is:
Magnetron tube core is placed in the main magnet of MRI system by the present invention, the i.e. main field common magnet of magnetron and MRI system, make the application scenario structure that magnetron is being provided with MRI system compacter, also make the tube core of magnetron can be operated in stronger magnetic field, thus produce the electromagnetic wave exporting higher frequency, more high-output power.
The D flask of cyclotron is placed in the main magnet of MRI system by the present invention, the uniform magnetic field for making charged particle move in a circle in cyclotron is served as by the main field of MRI system, the i.e. main field common magnet of D flask and MRI system, make the application scenario radius of gyration that cyclotron is being provided with MRI system can accomplish less, structure is compacter, magnetron is arranged on the main field of MRI system simultaneously, form the electromagnetic wave of more high frequency, the alternating electric field for charged particles such as accelerating protons on D flask is generated with this, to improve radiotherapeutic effect further.
Because the main magnet of described MRI system adopts superconducting magnet, the magnetic field intensity that superconducting magnet produces cryogenic magnetic field can reach several ten thousand Gausses, and therefore described magnetron becomes the electromagnetic wave drive source with altofrequency, short wavelength, high-power output.Also therefore, make the adjacent cavities of electron linear accelerator distance less, thus make the structure of electron linear accelerator compacter, expand application and the scope of application of electron linear accelerator further.Such as described magnetron is combined with X-band accelerating tube, can obtain X source that is compacter, high strength, and such light source is conducive to the manipulation of robot, thus shortens treatment time, reduces treatment cost.
The radiotherapy machine that MRI of the present invention guides makes magnetron and MRI system share main magnet (employing superconducting magnet), utilizes the high-intensity magnetic field of MRI, magnetron output is enlarged markedly.Particularly at X-band, also reduce the size of whole radiotherapy machine simultaneously and reduce cost.Owing to being operated in the electron linear accelerator compact of X-band, in addition the electromagnetic wave that magnetron exports more short wavelength is conducive to reducing further the size of electron linear accelerator, the electron linear accelerator as x-ray source is made to be easier to be manipulated by robot, thus make radiotherapy machine of the present invention can fast, precise delivery line is to the irradiation position of specifying, further shorten treatment time, reduce treatment cost, also help increase and more treat function, therefore possess stronger treatment ability.
Owing to being provided with online MR imaging apparatus, nuclear magnetic resonance can be carried out when radiotherapy, based on nuclear magnetic resonance, carry out radiation guide, given full play to thus MRI display tumor target and around the high-resolution of sensitive organization, the ability of high-contrast and the motion of dynamic tracking target area, avoid the additional injuries because X-ray scanning and imaging bring to patient's normal structure simultaneously, and adopt robot to drive electron linear accelerator motion, can multi-angle, the realization of the non-coplanar multi-faceted therapy apparatus of control is accurately to the location of focus target area and treatment, the electron linear accelerator on robot top can under strong magnetic field circumstance fast, precise delivery radiotherapy line is to the irradiation position of specifying, thus radiotherapy machine is had more treat function to patient, treat ability and better therapeutic effect more by force, owing to there is the less radiation dose to nonneoplastic tissue and more accurately to the definition of tumor target, thus there is better biological effect, be conducive to advancing radiotherapy technology to enter the New Times.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment one of the radiotherapy machine that MRI of the present invention guides;
Fig. 2 is the structural representation of the embodiment two of the radiotherapy machine that MRI of the present invention guides;
Fig. 3 is the structural representation of the embodiment three of the radiotherapy machine that MRI of the present invention guides;
Fig. 4 is the structural representation of the embodiment four of the radiotherapy machine that MRI of the present invention guides;
Fig. 5 is the structural representation of the embodiment five of the radiotherapy machine that MRI of the present invention guides;
Fig. 6 is the structural representation of the embodiment six of the radiotherapy machine that MRI of the present invention guides.
Detailed description of the invention
The invention provides a kind of accelerator, be provided with magnetron, described magnetron comprises tube core and magnet, described magnet adopts MRI(MagneticResonanceImaging, nuclear magnetic resonance) the main magnet of system, described tube core is arranged in the main field of the described MRI system produced by described main magnet, and the axis direction of described tube core is along the magnetic line of force direction of described main field.
Described accelerator is linear accelerator or cyclotron, described linear accelerator is provided with the accelerating tube accelerated for charged particle, described cyclotron is provided with the D flask accelerated for charged particle, the main magnet of described MRI system adopts superconducting coil, and described cyclotron D flask is also arranged in the main field of described MRI system.
Described MRI system include for generation of magnetic field of high uniformity main field and be used for producing and control the gradient magnetic of main field magnetic field gradient, correspondingly, main field adopts main magnet to be formed, and gradient magnetic adopts three groups of coils to produce, and produces the gradient fields in x, y, z three directions respectively.That described main field all refers to be produced by main magnet, be positioned at the magnetic field of main magnet physically within institute's restriceted envelope.
The magnetic field intensity producing cryogenic magnetic field due to superconducting magnet can reach several ten thousand Gausses, and exceed magnet order of magnitude of existing magnetron, the electromagnetic wave that therefore described magnetron can be made to export has higher frequency, shorter wavelength, higher power.More high-octane driving electromagnetic wave can be provided thus for accelerator.
When magnetron or its for accelerator be used in MRI system time, adopt magnetron of the present invention that equipment overall structure can be made compacter, be also conducive to the cost reducing whole device systems.
Described main magnet can be flat main magnet or the main magnet of drum type brake, and described flat main magnet comprises parallel two magnetic poles be oppositely arranged, and the magnetic field between two described magnetic poles forms described main field; The cylindrical shape of the main magnet of described drum type brake, the magnetic field in its axial bore is described main field.
When described main magnet is the main magnet of drum type brake, the axis of described tube core can with the dead in line of described main magnet, make the magnetic force uniformity be more subject in described tube core everywhere.
Because magnetron of the present invention can export the electromagnetic wave of more short wavelength, especially for the accelerator being operated in PI-pattern, because wavelength is shorter, in accelerator, the distance of adjacent cavities is less, therefore electron linear accelerator structure of the present invention is compacter, expands application and the scope of application of electron linear accelerator further.Such as described magnetron is combined with X-band accelerating tube, can obtain X source that is compacter, high strength, and such light source is conducive to the manipulation of robot, contributes to shortening treatment time in MRI system, reduces treatment cost.
As shown in figures 1 to 6, present invention also offers the radiotherapy machine that a kind of MRI guides, form primarily of radiotherapy machine and online MR imaging apparatus, described radiotherapy machine is provided with the accelerator accelerated for charged particle, comprise linear accelerator 10 and/or cyclotron 90, described accelerator is connected with the tube core 60 of a magnetron by waveguide 80, described online MR imaging apparatus is provided with the main magnet for the formation of MRI main field, the tube core of described magnetron is arranged in described MRI main field, the stationary magnetic field of described magnetron is served as with described MRI main field, described linear accelerator is positioned at the outside of described main magnet.
Described online MR imaging apparatus is provided with the main magnet for the formation of main field, and described main magnet adopts superconducting coil.
Described main magnet is flat main magnet or the main magnet of drum type brake, and described flat main magnet comprises parallel two magnetic poles be oppositely arranged, and the magnetic field between two described magnetic poles forms described main field; The cylindrical shape of the main magnet of described drum type brake, the magnetic field in its axial bore is described main field.
Described main magnet is provided with the treatment window 70 passed through for treatment line.
In the uniform magnetic field that the superconducting coil that magnetron tube core is placed in magnetic resonance imaging system produces, generate electromagnetic waves.Electromagnetic wave enters in the accelerating tube of electron linear accelerator, to Accelerating electron through described waveguide after drawing from the anode resonant cavity of magnetron.Electronics after acceleration is got to and is rotated on tungsten target and can produce X-ray.For treatment line (electronics or X-ray) by described treatment window inject in main field by treatment plan arrange therapy area, thus, radiotherapy is carried out to lesions position.
Described electron linear accelerator is arranged on the mechanical arm of robot, drives its motion (changing position and/or direction) by described robot.Adjust direction and the position of the relatively described treatment window of described electron linear accelerator, so that line is shipped to therapy area.
Preferably, described robot adopts the cascade machine mechanical arm 21 with 6 degree of freedom, and described electron linear accelerator is arranged on the top of described cascade machine mechanical arm, is in required optional position and arbitrarily angled to make described electron linear accelerator.
Preferably, described robot is also provided with walking mechanism, described walking mechanism comprises the robot base 22 for installing described cascade machine mechanical arm and is arranged on the robot ambulation wheel 23 below described robot base, also comprise the hoofing part mechanism for the motion of driven machine people road wheel, thus, can, by the stabilized walking of walking mechanism control, electron linear accelerator be in effectively or optimum position.
Optionally, be surrounded with around described online MR imaging apparatus and take turns supporting track with described robot ambulation, enable robot around online MR imaging apparatus thus.
Described electron linear accelerator preferably adopts the accelerating tube of X-band, and structure is compact more, is conducive to the manipulation of robot.
The support 34 that described online MR imaging apparatus is provided with base 35 and is arranged on base, described two magnetic poles are installed on described support.
Described online MR imaging apparatus is also furnished with corresponding therapeutic bed 50, to facilitate the transfer of patient.
When adopting cyclotron, the electromagnetic wave that described magnetron is drawn provides radio-frequency driven power, to form high-frequency electric field through the D flask that waveguide 80 is cyclotron.The charged particle beam that D flask exports is exported by charged particle path 10 0, injects the therapy area arranged by treatment plan in main field, thus, carry out radiotherapy to lesions position through described treatment window.
Described main magnet can be that flat main magnet 30(is see Fig. 1,2) or the main magnet 40(of drum type brake see Fig. 3,4,5,6).
Described flat main magnet can comprise parallel two magnetic poles 31,32 be oppositely arranged, and the space 33 between two described magnetic poles is described main field region, is also imaging area for treatment simultaneously.One or more support post 38 can be provided with between two described magnetic poles.
Described treatment window can adopt the combination of any one structural shape following or two kinds of structural shapes:
Region that corresponding any pair edge of (1) two described magnetic pole limits (when a pair sides aligned parallel that two described magnetic poles are corresponding is arranged, this region is plane domain, lower with) forms described treatment window (see Fig. 1);
(2) any one or two described magnetic poles are provided with opening 70, and described opening forms described treatment window (see Fig. 2).
Patient is sent to described imaging area for treatment by therapeutic bed, and the therapeutic bed that therapeutic bed passes in and out described imaging area for treatment imports and exports the region for any pair edge that two described magnetic poles are corresponding limits.For rectangular flat magnetic pole, every bar limit of magnetic pole all can be imported and exported by a corresponding therapeutic bed, specifically arranges which or which therapeutic bed import and export and determines depending on the structure that has of whole device systems.
When described treatment window adopts structural shape (1), described therapeutic bed import and export, described treatment window and the region becoming edge to limit that preferably corresponding two different described magnetic poles are corresponding respectively, described tube core position; When moving to avoid described therapeutic bed or described electron linear accelerator as far as possible, interfere with other both.
The cylindrical shape of the main magnet of described drum type brake, be centered around the magnet formed by serpentine pipe in a closed cylinder, its axial bore 42 be described main field region, while be also imaging area for treatment.Described treatment window can adopt any one structural shape following:
(1) any open at one end of described main magnet axial forms described treatment window 70(see Fig. 3);
(2) described main magnet is integral type structure, which is provided with radial aperture, and described radial aperture forms described treatment window (see Fig. 4); Or described main magnet is split-type structural, comprise the forward and backward two parts axially arranged, leave gap between described forward and backward two parts, the surperficial annular region between described forward and backward two parts forms described treatment window (see Fig. 5).
When described treatment window adopts said structure pattern (1), described main magnet is split-type structural, comprise the forward and backward two parts 43,44 axially arranged, leave gap between described forward and backward two parts, described gap forms the passage that the placement location of therapeutic bed in treatment and described therapeutic bed pass in and out described main field.The open at both ends of corresponding described main magnet axial is preferably distinguished in described treatment window and described tube core position.
When described treatment window adopts said structure pattern (2), therapeutic bed imports and exports any open at one end for described main magnet axial.The open at both ends of corresponding described main magnet axial is preferably distinguished in described therapeutic bed import and export and described tube core position.
For the main magnet of described drum type brake, the axis of described tube core preferably with the dead in line of described main magnet.
Described radiotherapy machine is electron beam radiotherapy machine, X-ray radiotherapy machine, proton radiotherapy machine or heavy ion radiotherapy machine, when described radiotherapy machine be electron beam radiotherapy machine or X-ray radiotherapy machine time, described accelerator is electron linear accelerator, described electron linear accelerator is one or more, each described electron linear accelerator is arranged on one and has on multivariant mechanical arm, when described radiotherapy machine be proton radiotherapy machine or heavy ion radiotherapy machine time, described accelerator is cyclotron, the D flask of described cyclotron is arranged in the main field of described MRI system, and the centerline direction of D flask is along the magnetic line of force direction of main field, preferably overlap with the magnetic line of force of main field.
Below for the X-ray radiotherapy machine based on electron linear accelerator, the concrete steps for the treatment of are as follows:
1, patient is placed in the magnetic field that formed with main magnet of online nuclear magnetic resonance of following the tracks of for radiotherapy in the treatment target area;
2, MRI imaging adjust patient location and make therapy area towards X-ray incidence window (namely treating window);
3, according to treatment plan, manipulated by robot, x-ray source being in its X-ray will be shipped in the orientation of therapy area.Arrange/adjust electron energy according to treatment plan;
4, arrange/adjust electron gun line over time according to treatment plan;
5, arrange/adjust X-ray incoming position and angle according to treatment plan;
6, arrange/adjust vane grating (controlling adjustment assembling not draw) according to treatment plan;
7, start electron linear accelerator and start treatment;
8, MRI imaging is implemented to follow the tracks of target area motion;
9, step 3-8 is repeated until treatment plan completes.
Claims (10)
1. an accelerator, be provided with magnetron, it is characterized in that described magnetron comprises tube core and magnet, described magnet adopts the main magnet of MRI system, described tube core is arranged in the main field of the described MRI system produced by described main magnet, and the axis direction of described tube core is along the magnetic line of force direction of described main field.
2. accelerator as claimed in claim 1, it is characterized in that described accelerator is linear accelerator or cyclotron, described linear accelerator is provided with the accelerating tube accelerated for charged particle, described cyclotron is provided with the D flask accelerated for charged particle, the main magnet of described MRI system adopts superconducting coil, and described cyclotron D flask is also arranged in the main field of described MRI system.
3. accelerator as claimed in claim 2, it is characterized in that described main magnet is flat main magnet or the main magnet of drum type brake, described flat main magnet comprises parallel two magnetic poles be oppositely arranged, and the magnetic field between two described magnetic poles forms described main field; The cylindrical shape of the main magnet of described drum type brake, the magnetic field in its axial bore is described main field.
4. the radiotherapy machine of a MRI guiding, form primarily of radiotherapy machine and online MR imaging apparatus, described radiotherapy machine is provided with the linear accelerator and/or cyclotron that accelerate for charged particle, described linear accelerator and cyclotron are provided with magnetron, described online MR imaging apparatus is provided with the main magnet for the formation of MRI main field, it is characterized in that the tube core of described magnetron is arranged in described MRI main field, serve as the stationary magnetic field of described magnetron with described MRI main field, described linear accelerator is positioned at the outside of described main magnet.
5. the radiotherapy machine of MRI guiding as claimed in claim 4, is characterized in that described main magnet adopts superconducting coil.
6. the radiotherapy machine of MRI guiding as claimed in claim 5, it is characterized in that described main magnet is flat main magnet or the main magnet of drum type brake, described flat main magnet comprises parallel two magnetic poles be oppositely arranged, and the magnetic field between two described magnetic poles forms described main field; The cylindrical shape of the main magnet of described drum type brake, the magnetic field in its axial bore is described main field.
7. the radiotherapy machine of MRI guiding as claimed in claim 6, it is characterized in that described main magnet is provided with the treatment window passed through for treatment line, when described main magnet is flat main magnet, described treatment window adopts the combination of any one structural shape following or two kinds of structural shapes:
The region that corresponding any pair edge of (1) two described magnetic pole limits forms described treatment window;
(2) any one or two described magnetic poles are provided with opening, and described opening forms described treatment window;
When described main magnet is the main magnet of drum type brake, described treatment window adopts any one structural shape following:
(1) any open at one end of described main magnet axial forms described treatment window;
(2) described main magnet is integral type structure, which is provided with radial aperture, and described radial aperture forms described treatment window; Or described main magnet is split-type structural, comprise the forward and backward two parts axially arranged, leave gap between described forward and backward two parts, the surperficial annular region between described forward and backward two parts forms described treatment window.
8. the radiotherapy machine of MRI guiding as claimed in claim 7, it is characterized in that for described flat main magnet, space between two described magnetic poles is imaging area for treatment, and therapeutic bed imports and exports the region for any pair edge that two described magnetic poles are corresponding limits; For the main magnet of described drum type brake, when described treatment window adopts said structure pattern (1), described main magnet is split-type structural, comprise the forward and backward two parts axially arranged, leave gap between described forward and backward two parts, described gap forms the passage that the placement location of therapeutic bed in treatment and described therapeutic bed pass in and out described main field; When described treatment window adopts said structure pattern (2), therapeutic bed imports and exports any open at one end for described main magnet axial.
9. the radiotherapy machine of MRI guiding as claimed in claim 8, it is characterized in that for described flat main magnet, when described treatment window adopts structural shape (1), described therapeutic bed import and export, described treatment window and the region becoming edge to limit that corresponding two different described magnetic poles are corresponding respectively, described tube core position; For the main magnet of described drum type brake, when described treatment window adopts said structure pattern (1), the open at both ends of described treatment window and the corresponding described main magnet axial of described tube core position difference; When described treatment window adopts said structure pattern (2), the open at both ends of described therapeutic bed import and export and the corresponding described main magnet axial of described tube core position difference.
10. the radiotherapy machine of MRI guiding as claimed in claim 9, it is characterized in that described radiotherapy machine is electron beam radiotherapy machine, X-ray radiotherapy machine, proton radiotherapy machine or heavy ion radiotherapy machine, when described radiotherapy machine be electron beam radiotherapy machine or X-ray radiotherapy machine time, described accelerator is electron linear accelerator, described electron linear accelerator is one or more, each described electron linear accelerator is arranged on one and has on multivariant mechanical arm, when described radiotherapy machine be proton radiotherapy machine or heavy ion radiotherapy machine time, described accelerator is cyclotron, the D flask of described cyclotron is arranged in the main field of described MRI system.
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| CN109562275A (en) * | 2016-07-14 | 2019-04-02 | 皇家飞利浦有限公司 | Mri guided treatment system |
| CN109562275B (en) * | 2016-07-14 | 2021-03-05 | 皇家飞利浦有限公司 | Magnetic resonance imaging guided therapy system and medium |
| US11357419B2 (en) | 2016-07-14 | 2022-06-14 | Koninklijke Philips N.V. | Magnetic resonance imaging guided therapy system |
| CN110152202A (en) * | 2018-02-01 | 2019-08-23 | 青岛大学附属医院 | A kind of clinical therapy of tumor equipment and its application method |
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