CN105362355A - Preparation method of Huoxue Tongluo oral liquid - Google Patents

Preparation method of Huoxue Tongluo oral liquid Download PDF

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Publication number
CN105362355A
CN105362355A CN201510876440.8A CN201510876440A CN105362355A CN 105362355 A CN105362355 A CN 105362355A CN 201510876440 A CN201510876440 A CN 201510876440A CN 105362355 A CN105362355 A CN 105362355A
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CN
China
Prior art keywords
preparation
oral liquid
radix
fluid extract
blood circulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510876440.8A
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Chinese (zh)
Inventor
郝青
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shaanxi Huanke Biotechnology Co Ltd
Original Assignee
Shaanxi Huanke Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Priority to CN201510876440.8A priority Critical patent/CN105362355A/en
Publication of CN105362355A publication Critical patent/CN105362355A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a preparation method of an oral liquid, in particular to a preparation method of Huoxue Tongluo oral liquid. The preparation method comprises following steps: washing herbs such as Radix Astragali, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra and Flos Carthami, adding water 5 times of the herbs, decocting them twice, first time for 1 h and second time for 0.5 h, combining herbal liquids, filtering a combination, concentrating filtrate to 1:1, adding 60%-70% ethyl alcohol into concentrate, mixing them well, allowing standing for 12 h for settling, and performing filtering prior to secondary settling. The preparation method has the advantages of process simplicity, industrial producibility and high practicality.

Description

A kind of preparation method of promoting blood circulation to remove obstruction in the collateral oral liquid
Technical field
The present invention relates to a kind of preparation method of Chinese medicine oral liquid, particularly a kind of preparation method of promoting blood circulation to remove obstruction in the collateral oral liquid.
Background technology
Promoting blood circulation to remove obstruction in the collateral oral liquid is with the Chinese traditional compound medicine of the multiple medicine composition such as the Radix Astragali, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Polygoni Ciliinerve, Pheretima, Rhizoma Chuanxiong, Flos Carthami, there is the effects such as benefiting QI for activating blood circulation, disperse blood stasis and dredge collateral, anticoagulating and lowering blood fat, be mainly used in the cardiovascular and cerebrovascular disease such as apoplexy sequela, cerebral thrombosis, cerebral arteriosclerosis and hypertension, hyperlipidemia, angina pectoris.
Summary of the invention
The present invention proposes a kind of preparation method of promoting blood circulation to remove obstruction in the collateral oral liquid.
The preparation method of promoting blood circulation to remove obstruction in the collateral oral liquid of the present invention, comprise the following steps: (1) gets the Radix Astragali, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the medical materials such as Flos Carthami, clean and add 5 times amount soak by water 2 times, 1 1h, 1 0.5h, merge medicinal liquid, filter, filtrate is concentrated into 1:1, concentrated solution is added 60%-70% ethanol to stir evenly, leave standstill 12h precipitation, again precipitate after filtration, add 70%-75% ethanol again to stir evenly, merge 2 filtrates, reclaim ethanol and be concentrated to fluid extract density 1.18-1.22, obtain fluid extract, fluid extract is added appropriate correctives, then adding distil water stirs evenly to 3000ml, regulate pH value to 6-7.5, leave standstill and filter, sterilizing both obtained promoting blood circulation to remove obstruction in the collateral oral liquid.
The preparation method of promoting blood circulation to remove obstruction in the collateral oral liquid of the present invention, preparation technology is simple, can suitability for industrialized production, practical.
Detailed description of the invention:
The preparation method of promoting blood circulation to remove obstruction in the collateral oral liquid of the present invention, comprise the following steps: (1) gets the Radix Astragali, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the medical materials such as Flos Carthami, clean and add 5 times amount soak by water 2 times, 1 1h, 1 0.5h, merge medicinal liquid, filter, filtrate is concentrated into 1:1, concentrated solution is added 60%-70% ethanol to stir evenly, leave standstill 12h precipitation, again precipitate after filtration, add 70%-75% ethanol again to stir evenly, merge 2 filtrates, reclaim ethanol and be concentrated to fluid extract density 1.18-1.22, obtain fluid extract, fluid extract is added appropriate correctives, then adding distil water stirs evenly to 3000ml, regulate pH value to 6-7.5, leave standstill and filter, sterilizing both obtained promoting blood circulation to remove obstruction in the collateral oral liquid.

Claims (1)

1. the preparation method of promoting blood circulation to remove obstruction in the collateral oral liquid, comprise the following steps: (1) gets the Radix Astragali, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the medical materials such as Flos Carthami, clean and add 5 times amount soak by water 2 times, 1 1h, 1 0.5h, merge medicinal liquid, filter, filtrate is concentrated into 1:1, concentrated solution is added 60%-70% ethanol to stir evenly, leave standstill 12h precipitation, again precipitate after filtration, add 70%-75% ethanol again to stir evenly, merge 2 filtrates, reclaim ethanol and be concentrated to fluid extract density 1.18-1.22, obtain fluid extract, fluid extract is added appropriate correctives, then adding distil water stirs evenly to 3000ml, regulate pH value to 6-7.5, leave standstill and filter, sterilizing both obtained promoting blood circulation to remove obstruction in the collateral oral liquid.
CN201510876440.8A 2015-12-03 2015-12-03 Preparation method of Huoxue Tongluo oral liquid Pending CN105362355A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510876440.8A CN105362355A (en) 2015-12-03 2015-12-03 Preparation method of Huoxue Tongluo oral liquid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510876440.8A CN105362355A (en) 2015-12-03 2015-12-03 Preparation method of Huoxue Tongluo oral liquid

Publications (1)

Publication Number Publication Date
CN105362355A true CN105362355A (en) 2016-03-02

Family

ID=55365309

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510876440.8A Pending CN105362355A (en) 2015-12-03 2015-12-03 Preparation method of Huoxue Tongluo oral liquid

Country Status (1)

Country Link
CN (1) CN105362355A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107802780A (en) * 2017-12-13 2018-03-16 孙建德 Shafulang oral liquid and preparation method thereof
CN109200201A (en) * 2018-11-12 2019-01-15 徐扬 A kind of compound leech thrombolysis capsule of hypertension and hyperlipemia hypoglycemic
CN110982655A (en) * 2019-12-24 2020-04-10 内蒙古中健宝生物科技有限公司 Preparation method of astragalus membranaceus health-care wine and astragalus membranaceus health-care wine prepared by same

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107802780A (en) * 2017-12-13 2018-03-16 孙建德 Shafulang oral liquid and preparation method thereof
CN109200201A (en) * 2018-11-12 2019-01-15 徐扬 A kind of compound leech thrombolysis capsule of hypertension and hyperlipemia hypoglycemic
CN110982655A (en) * 2019-12-24 2020-04-10 内蒙古中健宝生物科技有限公司 Preparation method of astragalus membranaceus health-care wine and astragalus membranaceus health-care wine prepared by same

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Application publication date: 20160302