CN105348820A - Simulated human skin material for nursing medical education as well as preparation method and application thereof - Google Patents

Simulated human skin material for nursing medical education as well as preparation method and application thereof Download PDF

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Publication number
CN105348820A
CN105348820A CN201510931737.XA CN201510931737A CN105348820A CN 105348820 A CN105348820 A CN 105348820A CN 201510931737 A CN201510931737 A CN 201510931737A CN 105348820 A CN105348820 A CN 105348820A
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skin material
religion
simulated humanbody
parts
doctor
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CN105348820B (en
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叶青华
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Qinghua Science And Education Equipment Co Ltd
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Qinghua Science And Education Equipment Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L91/00Compositions of oils, fats or waxes; Compositions of derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L53/02Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers of vinyl-aromatic monomers and conjugated dienes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L53/02Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers of vinyl-aromatic monomers and conjugated dienes
    • C08L53/025Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers of vinyl-aromatic monomers and conjugated dienes modified
    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00Polymer mixtures characterised by other features
    • C08L2205/03Polymer mixtures characterised by other features containing three or more polymers in a blend
    • C08L2205/035Polymer mixtures characterised by other features containing three or more polymers in a blend containing four or more polymers in a blend

Abstract

The invention discloses a simulated human skin material for nursing medical education. The simulated human skin material is prepared from the following components in parts by weight: 40 to 60 parts of SEBS, 30 to 50 parts of SBS, 50 to 100 parts of white oil, 1 to 5 parts of releasing agent, 1 to 2 parts of pigment and 0.5 to 1 part of antioxidant. The invention also discloses a preparation method of the material and a preparation method of preparing a human body model by adopting the material. The simulated human skin material has excellent demold performance, is non-toxic and environment friendly, smooth in surface, easy to size, realistic in hand feel, high in hardness, puncture-resistant, excellent in performance, and suitable for preparing simulated human skin teaching model and reaches a new height in the field of medical high polymer material processing.

Description

A kind of nursing doctor religion simulated humanbody skin material and preparation method thereof and application
Technical field
The present invention relates to polymeric material field, particularly a kind of nursing doctor religion simulated humanbody skin material and preparation method thereof and application.
Background technology
Nurse Major is that a technological operation is very strong, and the specialty of the communication exchange ability simultaneously requiring student to have, the teaching aid of therefore its practice must be true to nature, durable.The phantom of current Nurse Major is mostly adopt polyvinyl chloride (PVC) paste resin, is prepared from, as patent US5432222, EP0151040B2, CN103497448, CN1067062A by roto casting.Although but polyvinyl chloride material is cheap, feel is not good enough, and polyvinyl chloride not environmentally, meanwhile, the goods wearing quality of polyvinyl chloride is bad, especially not puncture, and these problems are all the very great problems that nursing speciality teaching aid faces.
Summary of the invention
In order to solve above-mentioned the deficiencies in the prior art, first object of the present invention is to provide a kind of nursing doctor religion simulated humanbody skin material, adopts the elastomer material of asepsis environment-protecting, not only has excellent feel and verisimilitude, and adopt the goods wearing quality of this material good, especially puncture.
To achieve these goals, the one nursing doctor religion simulated humanbody skin material designed by the present invention, comprises following parts by weight of component: SEBS40-60 part, SBS30-50 part, white oil 50-100 part, releasing agent 1-5 part, pigment 1-2 part, oxidation inhibitor 0.5-1 part.
Preferably, described SEBS is middle-molecular-weihydroxyethyl, and wherein divinyl and cinnamic ratio of weight and number are 60: 30 ~ 80: 20.
Preferably, described SBS is middle-molecular-weihydroxyethyl, and wherein divinyl and cinnamic ratio of weight and number are 60: 40 ~ 70: 30.
Preferably, described white oil is 50-100mm at the kinematic viscosity of 40 DEG C 2/ s.
Preferably, described releasing agent is a kind of multifunctional solid wax of multi-component copolymer, and its fusing point, at 60-70 DEG C, can select DZHA-200.
Preferably, described pigment is yellowish pink inorganic dyestuff.
Preferably, described oxidation inhibitor comprises bisphenols oxidation inhibitor and phosphite ester kind antioxidant.
Preferably, described bisphenols oxidation inhibitor is antioxidant 1010, and phosphite ester kind antioxidant is irgasfos 168, and the weight ratio of antioxidant 1010 and irgasfos 168 is 50: 50-70: 30.
The second object of the present invention is to provide a kind of preparation method of above-mentioned nursing doctor religion simulated humanbody skin material, comprises the following steps:
(1), by above-mentioned weight ratio take SEBS and SBS, put into homogenizer, stirring at room temperature 5-10min, stirring velocity is that 300-500 turns/min, obtained mixture I.
(2), by the white oil of above-mentioned weight ratio put into mixture I, homogenizer then stirs 20-30min, and stirring velocity turns/min at 500-1000, and temperature controls at 50-80 DEG C, obtained mixtures II.
(3), by the releasing agent of above-mentioned weight ratio, pigment and oxidation inhibitor, join and be cooled in the mixtures II of room temperature, homogenizer then stirs 5-10min, and stirring velocity turns/min at 300-800, temperature controls below 50 DEG C, obtained mixtures III.
(4), by mixtures III put into granulation in twin screw extruder, processing temperature controls at 100-150 DEG C, and particle dia is 1-3mm, i.e. obtained simulated humanbody skin material of the present invention.
The third object of the present invention is to provide a kind of preparation method nursing doctor's religion artificial human body model, above-mentioned simulated humanbody skin material is put in slush mold, processing temperature controls at 200-250 DEG C, controls process period at 60-90min, obtained artificial human body model.
One nursing doctor religion simulated humanbody skin material that the present invention obtains and preparation method thereof and application, its technique effect is: this simulated humanbody skin material not only has good release property, and this material non-toxic environmental protection, smooth surface, easily to shape, realistic hand feeling, hardness is high, puncture, excellent property, is applicable to preparation doctor religion simulated humanbody skin teaching mode, reaches new height in medical science field of high polymer material processing.
Embodiment
Below in conjunction with comparative example and embodiment, the present invention is further described.
Comparative example 1:
Take pvc resin paste grade 70 parts, polychloroethylene blending resin 30 parts, primary plasticizer 50 parts, 10 parts, secondary softening agent, stirrer put into by stablizer 8 parts, and stirring velocity is 300 turns/min, and temperature controls below 40 DEG C, stirs 15min, obtained liquid slurry.Liquid slurry is placed in encloses container, stirs 15min with the speed of 150 turns/min, then control vacuum values and vacuumize 50min after-0.09MPa, obtain polyvinyl chloride slush moulding material.Above-mentioned polyvinyl chloride slush moulding material is poured in the phantom mould of 200 DEG C of preheatings, at 230 DEG C, takes out phantom after rotational moulding 20min.
Wherein, primary plasticizer is phthalic ester plasticizer, and secondary softening agent can be alkylsulfonate plasticzer, and stablizer can be calcium-zinc composite stabilizing agent.
Embodiment 1:
Take SEBS50 part, SBS50 part, puts into homogenizer, at room temperature stirs 8min, and stirring velocity controls at 400 turns/min.Then add 75 parts of white oils, stirring velocity controls at 800 turns/min, and temperature controls at 70 DEG C, and churning time controls at 25min.When mixture is cooled to less than 50 DEG C, then add releasing agent 3 parts, pigment 1.5 parts and 0.8 part, oxidation inhibitor, continue to stir 8min, rotating speed controls at 500 turns/min.The mixture obtained is joined granulation in twin screw extruder (length-to-diameter ratio is 48: 1), processing temperature controls at 100-150 DEG C, and the particle diameter obtained is about 2mm.Particulate material is put into slush mold, and processing temperature controls at 220 DEG C, and time controling, at 70min, namely obtains doctor's religion artificial human body model.
Embodiment 2:
Take SEBS40 part, SBS60 part, puts into homogenizer, at room temperature stirs 8min, and stirring velocity controls at 400 turns/min.Then add 100 parts of white oils, stirring velocity controls at 800 turns/min, and temperature controls at 70 DEG C, and churning time controls at 25min.When mixture is cooled to less than 50 DEG C, then add releasing agent 3 parts, pigment 1.5 parts and 0.8 part, oxidation inhibitor, continue to stir 8min, rotating speed controls at 500 turns/min.The mixture obtained is joined granulation in twin screw extruder (length-to-diameter ratio is 48: 1), processing temperature controls at 100-150 DEG C, and the particle diameter obtained is about 2mm.Particulate material is put into slush mold, and processing temperature controls at 220 DEG C, and time controling, at 70min, namely obtains doctor's religion artificial human body model.
Embodiment 3:
Take SEBS60 part, SBS40 part, puts into homogenizer, at room temperature stirs 8min, and stirring velocity controls at 400 turns/min.Then add 50 parts of white oils, stirring velocity controls at 800 turns/min, and temperature controls at 70 DEG C, and churning time controls at 25min.When mixture is cooled to less than 50 DEG C, then add releasing agent 3 parts, pigment 1.5 parts and 0.8 part, oxidation inhibitor, continue to stir 8min, rotating speed controls at 500 turns/min.The mixture obtained is joined granulation in twin screw extruder (length-to-diameter ratio is 48: 1), processing temperature controls at 100-150 DEG C, and the particle diameter obtained is about 2mm.Particulate material is put into slush mold, and processing temperature controls at 220 DEG C, and time controling, at 70min, namely obtains doctor's religion artificial human body model.
Embodiment 4:
Take SEBS50 part, SBS50 part, puts into homogenizer, at room temperature stirs 8min, and stirring velocity controls at 400 turns/min.Then add 50 parts of white oils, stirring velocity controls at 800 turns/min, and temperature controls at 70 DEG C, and churning time controls at 25min.When mixture is cooled to less than 50 DEG C, then add releasing agent 5 parts, pigment 2 parts and 0.8 part, oxidation inhibitor, continue to stir 8min, rotating speed controls at 500 turns/min.The mixture obtained is joined granulation in twin screw extruder (length-to-diameter ratio is 48: 1), processing temperature controls at 100-150 DEG C, and the particle diameter obtained is about 2mm.Particulate material is put into slush mold, and processing temperature controls at 220 DEG C, and time controling, at 70min, namely obtains doctor's religion artificial human body model.
Embodiment 5:
Take SEBS50 part, SBS50 part, puts into homogenizer, at room temperature stirs 8min, and stirring velocity controls at 300 turns/min.Then add 50 parts of white oils, stirring velocity controls at 1000 turns/min, and temperature controls at 70 DEG C, and churning time controls at 30min.When mixture is cooled to less than 50 DEG C, then add releasing agent 5 parts, pigment 2 parts and 0.8 part, oxidation inhibitor, continue to stir 8min, rotating speed controls at 500 turns/min.The mixture obtained is joined granulation in twin screw extruder (length-to-diameter ratio is 48: 1), processing temperature controls at 100-150 DEG C, and the particle diameter obtained is about 1mm.Particulate material is put into slush mold, and processing temperature controls at 220 DEG C, and time controling, at 70min, namely obtains doctor's religion artificial human body model.
Embodiment 6:
Take SEBS50 part, SBS50 part, puts into homogenizer, at room temperature stirs 8min, and stirring velocity controls at 300 turns/min.Then add 50 parts of white oils, stirring velocity controls at 1000 turns/min, and temperature controls at 70 DEG C, and churning time controls at 30min.When mixture is cooled to less than 50 DEG C, then add releasing agent 5 parts, pigment 2 parts and 0.8 part, oxidation inhibitor, continue to stir 8min, rotating speed controls at 500 turns/min.The mixture obtained is joined granulation in twin screw extruder (length-to-diameter ratio is 48: 1), processing temperature controls at 100-150 DEG C, and the particle diameter obtained is about 3mm.Particulate material is put into slush mold, and processing temperature controls at 220 DEG C, and time controling, at 70min, namely obtains doctor's religion artificial human body model.
Embodiment 7:
Take SEBS50 part, SBS50 part, puts into homogenizer, at room temperature stirs 8min, and stirring velocity controls at 300 turns/min.Then add 50 parts of white oils, stirring velocity controls at 1000 turns/min, and temperature controls at 70 DEG C, and churning time controls at 30min.When mixture is cooled to less than 50 DEG C, then add releasing agent 5 parts, pigment 2 parts and 0.8 part, oxidation inhibitor, continue to stir 8min, rotating speed controls at 500 turns/min.The mixture obtained is joined granulation in twin screw extruder (length-to-diameter ratio is 52: 1), processing temperature controls at 100-150 DEG C, and the particle diameter obtained is about 3mm.Particulate material is put into slush mold, and processing temperature controls at 200 DEG C, and time controling, at 60min, namely obtains doctor's religion artificial human body model.
Embodiment 8:
Take SEBS50 part, SBS50 part, puts into homogenizer, at room temperature stirs 8min, and stirring velocity controls at 300 turns/min.Then add 50 parts of white oils, stirring velocity controls at 1000 turns/min, and temperature controls at 70 DEG C, and churning time controls at 30min.When mixture is cooled to less than 50 DEG C, then add releasing agent 5 parts, pigment 2 parts and 0.8 part, oxidation inhibitor, continue to stir 8min, rotating speed controls at 500 turns/min.The mixture obtained is joined granulation in twin screw extruder (length-to-diameter ratio is 52: 1), processing temperature controls at 100-150 DEG C, and the particle diameter obtained is about 3mm.Particulate material is put into slush mold, and processing temperature controls at 250 DEG C, and time controling, at 90min, namely obtains doctor's religion artificial human body model.
In above-described embodiment 1-8, SEBS is middle-molecular-weihydroxyethyl, and wherein divinyl and cinnamic ratio of weight and number are 60: 30 ~ 80: 20; SBS is also middle-molecular-weihydroxyethyl, and wherein divinyl and cinnamic ratio of weight and number are 60: 40 ~ 70: 30.
White oil is 50-100mm at the kinematic viscosity of 40 DEG C 2/ s.
Releasing agent is a kind of multifunctional solid wax of multi-component copolymer, and its fusing point is at 60-70 DEG C, and that select in embodiment 1-8 is DZHA-200.
Pigment is yellowish pink inorganic dyestuff.Oxidation inhibitor comprises bisphenols oxidation inhibitor and phosphite ester kind antioxidant.In embodiment 1-8, bisphenols oxidation inhibitor is antioxidant 1010, and phosphite ester kind antioxidant is irgasfos 168, and the weight ratio of antioxidant 1010 and irgasfos 168 is 50: 50-70: 30.
According to above-mentioned comparative example 1 and embodiment 1-8, feel is carried out to obtained nursing doctor religion artificial human body model and compares with puncture, obtain table 1:
Table 1: embodiment 1-8 and comparative example 1 material property comparison sheet
Numbering Feel * Paracentesis resistance * *
Comparative example 1 0 0
Embodiment 1 + △△△
Embodiment 2 + △△
Embodiment 3 +++ △△
Embodiment 4 ++
Embodiment 5 ++
Embodiment 6 +++ △△△
Embodiment 7 + △△
Embodiment 8 ++ △△
In table 1, *: 0 representative is poor, in+representative, ++ represent good, +++ represent outstanding; *: 0 representative is poor, and in △ representative, △ △ represents good, and △ △ △ represents outstanding.
As shown in Table 1, apply the phantom that simulated humanbody skin material of the present invention is obtained, relative contrast's example 1, feel and puncture performance are significantly improved; And SEBS and the SBS asepsis environment-protecting adopted in the present invention, be conducive to the protection of environment, be adapted at promoting on a large scale in medical education.

Claims (10)

1. a nursing doctor religion simulated humanbody skin material, is characterized in that: comprise following parts by weight of component: SEBS40-60 part, SBS30-50 part, white oil 50-100 part, releasing agent 1-5 part, pigment 1-2 part, oxidation inhibitor 0.5-1 part.
2. nursing doctor religion simulated humanbody skin material according to claim 1, it is characterized in that: described SEBS is middle-molecular-weihydroxyethyl, wherein divinyl and cinnamic ratio of weight and number are 60: 30 ~ 80: 20.
3. nursing doctor religion simulated humanbody skin material according to claim 1, it is characterized in that: described SBS is middle-molecular-weihydroxyethyl, wherein divinyl and cinnamic ratio of weight and number are 60: 40 ~ 70: 30.
4. nursing doctor religion simulated humanbody skin material according to claim 1, is characterized in that: described white oil is 50-100mm at the kinematic viscosity of 40 DEG C 2/ s.
5. nursing doctor religion simulated humanbody skin material according to claim 1, is characterized in that: described releasing agent is a kind of multifunctional solid wax of multi-component copolymer, and its fusing point is at 60-70 DEG C.
6. nursing doctor religion simulated humanbody skin material according to claim 1, is characterized in that: described pigment is yellowish pink inorganic dyestuff.
7. nursing doctor religion simulated humanbody skin material according to claim 1, is characterized in that: described oxidation inhibitor comprises bisphenols oxidation inhibitor and phosphite ester kind antioxidant.
8. nursing doctor religion simulated humanbody skin material according to claim 7, it is characterized in that: described bisphenols oxidation inhibitor is antioxidant 1010, phosphite ester kind antioxidant is irgasfos 168, and the weight ratio of antioxidant 1010 and irgasfos 168 is 50: 50-70: 30.
9. a preparation method for claim 1-8 arbitrary described nursing doctor religion simulated humanbody skin material, is characterized in that, comprise the following steps:
(1), by above-mentioned weight ratio take SEBS and SBS, put into homogenizer, stirring at room temperature 5-10min, stirring velocity is that 300-500 turns/min, obtained mixture I.
(2), by the white oil of above-mentioned weight ratio put into mixture I, homogenizer then stirs 20-30min, and stirring velocity turns/min at 500-1000, and temperature controls at 50-80 DEG C, obtained mixtures II.
(3), by the releasing agent of above-mentioned weight ratio, pigment and oxidation inhibitor, join and be cooled in the mixtures II of room temperature, homogenizer then stirs 5-10min, and stirring velocity turns/min at 300-800, temperature controls below 50 DEG C, obtained mixtures III.
(4), by mixtures III put into granulation in twin screw extruder, processing temperature controls at 100-150 DEG C, and particle dia is 1-3mm, i.e. obtained simulated humanbody skin material of the present invention.
10. nurse the preparation method of doctor's religion artificial human body model for one kind, it is characterized in that: the claims 9 are obtained simulated humanbody skin material and is put in slush mold, processing temperature controls at 200-250 DEG C, controls process period at 60-90min, obtained artificial human body model.
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