CN105343833A - Pharmaceutical composition for treating bronchopneumonia - Google Patents
Pharmaceutical composition for treating bronchopneumonia Download PDFInfo
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Abstract
The invention relates to a pharmaceutical composition for treating bronchopneumonia. The pharmaceutical composition is composed of the following traditional Chinese medicine raw materials according to a weight ratio: 3-7 parts of winged laggera herb, 3-5 parts of old radish root, 2-5 parts of flower of aglaia odorata, 5-8 parts of whole herb of amethystea caerulea, 5-10 parts of whole herb of andrographis laxiflora, 3-7 parts of root of artemisia dracunculus, 3-7 parts of whole herb of lysimachia microcarpa, 2-8 parts of rhizome of mioga ginger, 3-5 parts of capitulum of picris hieracioides, 3-5 parts of whole herb of salvia substolonifera, 5-12 parts of involute spikemoss herb, 5-10 parts of cryptoporus volvatus, 3-8 parts of whole herb of juncellus serotinus, 3-7 parts of cudweed herb, 3-5 parts of ludwigia hyssopifo-lia (G.Don)Exekk, 2-7 parts of whole herb and flower of lotus corniculatus, 3-7 parts of roots and rhizomes of primula sieboldii, 5-15 parts of Indian rorippa herb and 5-15 parts of roots or whole herb of wahlenbergia marginata. The pharmaceutical composition has the efficacies of clearing heat, ventilating the lung, clearing away phlegm, relieving asthma, relieving cough, reducing sputum, invigorating qi and strengthening spleen, has a definite and remarkable curative effect for treating bronchopneumonia, is high in effective rate and safe, has no toxic or side effects and is low in possibility of relapse.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to one and treat bronchopneumonic pharmaceutical composition.
Background technology
Bronchopneumonia is one of Childhood common respiratory tract disease.Onset is comparatively anxious, is clinically dispersed in moist rales for principal character with heating, cough, out of breath, flaring of nares and pulmonary.Be more common in the infant of less than 3 years old, the most easily occur when winter-spring season and weather cataclysm.If can treat in time in early days, prognosis bona.Age is immature, and body constitution is poor again at ordinary times, and after ill, the state of an illness easily repeatedly, causes delay difficult.The primary disease traditional Chinese medical science thinks to be being invaded by exogenous pathogen, caused by closing lung network, claims " pneumonia asthma is coughed ", " dyspnea and cough due to the lung-wind syndrome with phlegm ", " horse board wind " etc.
The primary disease cause of disease has inside and outside two aspects.Outer because experience ailment said due to cold or exposure, invade caused by lung meridian, ailment said due to cold or exposure has dividing of wind and cold, wind heat; Interior because children's's shape gas does not fill, lungs are tender and lovely, weakened defensive QI, easily cause exopathogen to attack lung meridian, cause pneumonia.Also have because of after the acute calentures such as measles, pertussis, scarlet fever, evil poison invasion and attack lung meridian causes a disease; Or congenital defect, lose the day after tomorrow and support, ferritic is weak, ill rear normal protracted course of disease.Though pathogenesis has difference, its sick position is all at lung meridian.Pathological change is that heresy is invaded in lung, the strongly fragrant resistance of lung qi, strongly fragrant and heat-dissipating, and lung-heat is fumigated, and bright Tianjin is expectorant, sputum retardance lung network, and air flue is jammed for it, so that lung qi is inaccessible and fall ill.Lung governing qi, department breathes, and outer conjunction fur, has one's ideas straightened out in nose, is source on human body water, lung qi is suitable to drop to, and rises to inverse, expectorant evil mutual resistance lung network, and lung qi loses in a surname respectful,, can there is fever and cough, lung qi closing in space between skin and muscles folding mistake degree, retardance is not smooth and see obvious flaring of nares out of breath.Qi as the commander of blood, the capable then blood of gas, the stagnation of QI is stasis then, and the resistance of lung network numbness is visible face and cyanotic lips then, notably causes flaccidity of the heart-yang, heart failure.When pathogenic heat run wild, cave in the moon of fainting, also can priming liver-wind and coma, tic.
At present, bronchopneumonic treatment often adopts the Western medicine such as Chuan Le Ning, salbutamol, budesonide and auxiliary antibiotic therapy, and side effect is large.
Summary of the invention
The object of the present invention is to provide a kind of evident in efficacy, effective percentage is high, the bronchopneumonic pharmaceutical composition for the treatment of that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: one treats bronchopneumonic pharmaceutical composition, by following weight proportioning raw material of Chinese medicine form: Herba Laggerae Alatae 3-7 part, Radix Raphani 3-5 part, Flos Aglaiae Odoratae flower 2-5 part, water Spina jujubae 5-8 part, spend Herba Andrographis 5-10 part in vain, green pepper Artemisia 3-7 part, fruitlet Herba lysimachiae capillipedis 3-7 part, Rhizoma zingiberis miogae 2-8 part, Fols Picridis fuscipilosae 3-5 part, province of the Yuan Dynasty grass 3-5 part, Herba Selaginellae Involventis 5-12 part, Cryptoporus volvatus (peck) Scnear 5-10 part, Herba Cyperi Glomerati 3-8 part, Herba Gnaphalii Affinis 3-7 part, the imperial root 3-5 part of grass, Herba Loti Corniculati 2-7 part, Radix Primulae sieboldii 3-7 part, Herba Rorippae 5-15 part, Herba Wahlenbergiae 5-15 part.
Preferably, one treats bronchopneumonic pharmaceutical composition, by following weight proportioning raw material of Chinese medicine form: Herba Laggerae Alatae 5 parts, Radix Raphani 4 parts, Flos Aglaiae Odoratae spends 3 parts, water Spina jujubae 7 parts, spends Herba Andrographis 8 parts in vain, green pepper Artemisia 5 parts, fruitlet Herba lysimachiae capillipedis 5 Fen ， Rhizoma zingiberis miogae 5 parts, Fols Picridis fuscipilosae 5 parts, province of the Yuan Dynasty grass 3 parts, Herba Selaginellae Involventis 10 parts, Cryptoporus volvatus (peck) Scnear 10 parts, Herba Cyperi Glomerati 7 parts, Herba Gnaphalii Affinis 5 parts, careless imperial root 4 parts, Herba Loti Corniculati 5 parts, Radix Primulae sieboldii 5 Fen ， Herba Rorippae 10 parts, Herba Wahlenbergiae 10 parts.
The pharmacologically active of each raw material of Chinese medicine of the present invention is as follows:
Herba Laggerae Alatae, is the herb of feverfew Laggera alata (Roxb.) Sch.-Bip., dispels the wind, and dehumidifying, changes stagnant, dissipating blood stasis, detumescence, removing toxic substances.Cure cold cough body pain, stomachache dysentery, rheumatic arthritis, women's amenorrhea, traumatic injury, furuncle carbuncle scrofula, noxious dampness pruritus." east, Fujian book on Chinese herbal medicine ": " deliver wind dispelling, lung qi dispersing reason spleen, stimulate the menstrual flow blood stasis dispelling.Control headache due to invasion of exogenous pathogens, arthralgia, abdominal distention is suffered from abdominal pain, and stagnates and has loose bowels, married woman's amenorrhea.
Radix Raphani is the old root of crucifer Radix Raphani, Gan Xin, flat.Dispersing lung-QI and dissipating phlegm, helps digestion, diuretic.Control cough ant phlegm, stagnation of QI due to dyspepsia, the vexed distending pain of gastral cavity abdomen painful abdominal mass, edema dyspnea with fullness of the chest, fasting dysentery disease." classifying herbal ": " relieving cough and resolving phlegm, detumescence gas, area, controls dysentery disease.″
Flos Aglaiae Odoratae flower is the flower of Meliaceae plant Flos Aglaiae Odoratae, pungent, sweet, flat, promoting the circulation of QI to alleviate the stagnation in middle-JIAO; Lung qi dispersing cough-relieving.Main chest and diaphragm is full vexed; Dysphagic from the beginning of; Cold cough.
Water Spina jujubae is the herb of labiate water Spina jujubae, acrid in the mouth, and property is put down, and returns lung meridian, dispelling wind to relieve the exterior syndrome; Depressed lung-energy dispersing.Main flu; Cough and asthma.
Spending Herba Andrographis in vain, is the herb of acanthaceous plant palpus medicinal herbs, and acrid in the mouth is bitter, cool in nature, loose wind heat; Lung qi dispersing gas; Adjust the intestines and stomach.Main cold, fever; Lung-heat cough with asthma; Vomiting; Have loose bowels.
Green pepper Artemisia is the herb root of feverfew Artemisia dracunculus, acrid in the mouth, and micro-hardship is warm in nature, expelling wind and cold; Lung qi dispersing cough-relieving.Main anemofrigid cold; Cough and asthma.
Fruitlet Herba lysimachiae capillipedis is the herb of Ofthe Primulaceae fruitlet Rhizoma et radix valerianae, sweet, pungent, and property is put down, and induce sweat lung qi dispersing; Relieving cough and asthma.Main flu; Cough; Asthma.
Rhizoma zingiberis miogae, for Jiang Ke plants the rhizome of thing Rhizoma zingiberis miogae, acrid in the mouth, warm in nature, return lung, Liver Channel, promoting blood flow to regulate menstruation, relieving cough and expelling phlegm, subduing swelling and detoxicating.Control menoxenia, old cough, skin ulcer swells, scrofula, conjunctival congestion, sore throat.
Fols Picridis fuscipilosae is the head inflorescence of the brown Fols Picridis fuscipilosae of feverfew, bitter in the mouth, slightly warm in nature, the cough-relieving of reason lung; Resolving phlegm and relieving asthma; The chest stuffiness relieving.Main cough with copious phlegm; Cough with asthma; Belch; Born of the same parents' abdomen is vexed swollen.
Province of the Yuan Dynasty grass is the herb of labiate flammule grass, micro-hardship, pungent, flat, clearing away heat-damp and promoting diuresis, antiasthmatic-antitussive, regulating menstruation, hemostasis.For rheumatism cough, abundant expectoration is panted, and spits blood, leucorrhea, frequent micturition, lumbago, menorrhagia.
Herba Selaginellae Involventis is the herb of Spikemoss plant Herba Selaginellae Involventis, light, micro-hardship, cool, returns lung, liver, the heart, spleen channel, clearing away heat-damp and promoting diuresis; Cough-relieving; Hemostasis; Removing toxic substances.Main jaundice due to damp-heat; Dysentery; Edema; Ascites; Stranguria; Productive cough due to phlegm-damp; Spitting of blood; Spit blood; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Acute mastitis; Scrofula; Hemorrhoid; Scald.Quanzhou book on Chinese herbal medicine ": clear away heart-fire hemostasis, arresting convulsion relieving convulsion, resolving phlegm and relieving asthma.Control hematemesis and epistaxis, lung abscess pus and blood, coughing and wheezing.
Cryptoporus volvatus (peck) Scnear is the sporophore of the hidden pore fungi of On Polyporaceae, bitter, flat, cough-relieving; Relieving asthma; Removing toxic substances.Main bronchus is scorching; Asthma; Hemorrhoid; Have a toothache.
Herba Cyperi Glomerati is the herb of the spherical dried tuber of sedge, bitter, and flat, cough-relieving, removing blood stasis, stimulates the menstrual flow, circulation of qi promoting, removing food stagnancy, pain relieving.For chronic tracheitis, lump in the abdomen, postpartum stagnation is suffered from abdominal pain; Dyspepsia, amenorrhea and all stagnation of QI-bloods, breast abdominal rib pain.
Herba Gnaphalii Affinis is the herb of feverfew Herba Gnaphalii Affinis, sweet, flat, relieving cough and asthma, blood pressure lowering, wind-damp dispelling.For cold cough, bronchitis, asthma, hypertension, favism, lumbago, skelalgia of rheumatism; Traumatic injury is controlled in external, venom.
The imperial root of grass is the root of onagraceae plant line leaf Herba Ludwigiae Prostratae, bitter in the mouth, and property is put down, antiasthmatic-antitussive; Removing food stagnancy; Eliminating stagnation.Main asthma; Cough; Infantile malnutrition; Scrofula.
Herba Loti Corniculati is herb and the flower of leguminous plant Radix Loti Corniculati, sweet, and micro-hardship is cool, attaches to the lung and stomach meridians, heat-clearing and toxic substances removing; Relieving cough and asthma; Dampness removing disappears painful abdominal mass.Main air heat cough; Laryngopharynx swelling and pain; Gastral cavilty feeling of fullness pain; Furuncle; Innominate toxic swelling; Eczema; Dysentery; Hemorrhoidal hemorrhage.
Radix Primulae sieboldii is the root and rhizome that Primulaceae Cui Nan is heralded spring, sweet; Property is put down, preventing phlegm from forming and stopping coughing.Main cough with asthma abundant expectoration." Jilin Chinese herbal medicine ": " relieving cough and resolving phlegm.Control phlegm dyspnea cough.″
Herba Rorippae is herb or the flower that thing Herba Rorippae is planted by ten Zi Hua sections, acrid in the mouth, and bitter, slightly warm in nature, returns lung, Liver Channel, expelling phlegm for arresting cough; Induce sweat cold expelling; Promoting blood circulation and detoxication; Dampness removing jaundice eliminating.Main cough phlegm dyspnea; Cold, fever; Measles is sent out not smooth thoroughly; Rheumatic arthralgia; Laryngopharynx swelling and pain; Furuncle carbuncle; Dermatitis rhus; Amenorrhea; Traumatic injury; Jaundice; Edema.
Herba Wahlenbergiae is root or the herb of Campanulaceae Radix Wahlenbergiae Marginatae, sweet in the mouth, micro-hardship, and property is put down, and returns spleen, lung meridian, replenishing QI to invigorate the spleen; Eliminating phlegm and stopping cough; Hemostasis.Main deficient impairment caused by overstrain; Spontaneous perspiration; Night sweat; Infantile malnutrition; Women leucorrhea; Flu; Cough; Epistaxis; Malaria; Scrofula.
The present invention has following beneficial effect: pharmaceutical composition of the present invention has effect of reducing heat and dispersing lung-QI, clearing away phlegm Dingchuan, relieving cough and resolving phlegm, replenishing QI to invigorate the spleen, and to bronchopneumonia determined curative effect, significantly, effective percentage is high, safe without toxic side effect, not easily recurs.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
One treats bronchopneumonic pharmaceutical composition, by following weight proportioning raw material of Chinese medicine form: Herba Laggerae Alatae 5 parts, Radix Raphani 4 parts, Flos Aglaiae Odoratae spends 3 parts, water Spina jujubae 7 parts, spends Herba Andrographis 8 parts in vain, green pepper Artemisia 5 parts, fruitlet Herba lysimachiae capillipedis 5 parts of Rhizoma zingiberis miogae 5 parts, Fols Picridis fuscipilosae 5 parts, province of the Yuan Dynasty grass 3 parts, Herba Selaginellae Involventis 10 parts, Cryptoporus volvatus (peck) Scnear 10 parts, Herba Cyperi Glomerati 7 parts, Herba Gnaphalii Affinis 5 parts, careless imperial root 4 parts, Herba Loti Corniculati 5 parts, Radix Primulae sieboldii 5 Fen ， Herba Rorippae 10 parts, Herba Wahlenbergiae 10 parts.
Embodiment 2
One treats bronchopneumonic pharmaceutical composition, by following weight proportioning raw material of Chinese medicine form: Herba Laggerae Alatae 3 parts, Radix Raphani 5 parts, Flos Aglaiae Odoratae spends 5 parts, water Spina jujubae 5 parts, spends Herba Andrographis 10 parts in vain, green pepper Artemisia 3 parts, fruitlet Herba lysimachiae capillipedis 7 parts of Rhizoma zingiberis miogae 2 parts, Fols Picridis fuscipilosae 4 parts, province of the Yuan Dynasty grass 3 parts, Herba Selaginellae Involventis 12 parts, Cryptoporus volvatus (peck) Scnear 5 parts, Herba Cyperi Glomerati 8 parts, Herba Gnaphalii Affinis 3 parts, careless imperial root 4 parts, Herba Loti Corniculati 3 parts, Radix Primulae sieboldii 3 Fen ， Herba Rorippae 12 parts, Herba Wahlenbergiae 15 parts.
Embodiment 3
One treats bronchopneumonic pharmaceutical composition, by following weight proportioning raw material of Chinese medicine form: Herba Laggerae Alatae 7 parts, Radix Raphani 5 parts, Flos Aglaiae Odoratae spends 4 parts, water Spina jujubae 6 parts, spends Herba Andrographis 5 parts in vain, green pepper Artemisia 6 parts, fruitlet Herba lysimachiae capillipedis 3 parts of Rhizoma zingiberis miogae 3 parts, Fols Picridis fuscipilosae 3 parts, province of the Yuan Dynasty grass 4 parts, Herba Selaginellae Involventis 8 parts, Cryptoporus volvatus (peck) Scnear 6 parts, Herba Cyperi Glomerati 3 parts, Herba Gnaphalii Affinis 6 parts, careless imperial root 5 parts, Herba Loti Corniculati 2 parts, Radix Primulae sieboldii 6 Fen ， Herba Rorippae 15 parts, Herba Wahlenbergiae 5 parts.
Embodiment 4
One treats bronchopneumonic pharmaceutical composition, by following weight proportioning raw material of Chinese medicine form: Herba Laggerae Alatae 6 parts, Radix Raphani 3 parts, Flos Aglaiae Odoratae spends 2 parts, water Spina jujubae 8 parts, spends Herba Andrographis 7 parts in vain, green pepper Artemisia 7 parts, fruitlet Herba lysimachiae capillipedis 4 parts of Rhizoma zingiberis miogae 8 parts, Fols Picridis fuscipilosae 3 parts, province of the Yuan Dynasty grass 5 parts, Herba Selaginellae Involventis 5 parts, Cryptoporus volvatus (peck) Scnear 8 parts, Herba Cyperi Glomerati 5 parts, Herba Gnaphalii Affinis 7 parts, careless imperial root 3 parts, Herba Loti Corniculati 7 parts, Radix Primulae sieboldii 7 Fen ， Herba Rorippae 5 parts, Herba Wahlenbergiae 8 parts.
Clinical data
Accept bronchopneumonia 560 example altogether for medical treatment, wherein male 312 example, women 248 example.
Therapeutic Method: pharmaceutical composition of the present invention is decocted in water for oral dose, every day potion, one day twice, sooner or later sub-service 10 days was a course for the treatment of.
Curative effect judging standard:
Cure: clinical symptom disappearance, more than half a year do not recur;
Effective: clinical symptom relief;
Invalid: clinical symptoms does not alleviate, even increase the weight of.
Therapeutic outcome: through 1-3 course of therapy, 560 routine patients cure 470 examples, effective 62 examples, and invalid 28 examples, cure rate 83.9%, total effective rate 95%, in therapeutic process, bad side reaction does not appear in patient.
Model case 1
Grandson, female, 2 years old August.Because " cough, asthma 4 days " is admitted to hospital.Occurred cough before 4 days, cough as paroxysmal cough, have expectorant, not easily expectoration, have asthma, without tachypnea, livid purple, the symptoms such as nothing heating, vomiting, diarrhoea, tic, night sweat, once gave associated medication therapies at local hospital, concrete medication is not quite clear, less effective.Greatly alleviate by symptom after the course for the treatment of of treatment by Chinese herbs of the present invention, the continual cure recovery from illness course for the treatment of, follows up a case by regular visits to and does not recur for 1 year.
Model case 2
Hu, man, 5 years old, before 1 week, occurred cough once in a while without obvious inducement, be paroxysmal cough, cough increases the weight of companion 3 days out of breath, has expectorant but not easily expectoration, has told watery nasal discharge, with heating, body temperature fluctuation, in about 37.6 ~ 38.2 DEG C, has vomiting when cough is fierce, and without diarrhoea, I goes to a doctor by Out-patient Department then.With after the course for the treatment of of treatment by Chinese herbs of the present invention, body temperature is normal, and cough alleviates, and continual cure one all diseases course for the treatment of are known except recovery from illness, follow up a case by regular visits to and do not recur for 1 year.
Claims (2)
1. treat a bronchopneumonic pharmaceutical composition, it is characterized in that, by following weight proportioning raw material of Chinese medicine form: Herba Laggerae Alatae 3-7 part, Radix Raphani 3-5 part, Flos Aglaiae Odoratae flower 2-5 part, water Spina jujubae 5-8 part, spends Herba Andrographis 5-10 part in vain, green pepper Artemisia 3-7 part, fruitlet Herba lysimachiae capillipedis 3-7 Fen ， Rhizoma zingiberis miogae 2-8 part, Fols Picridis fuscipilosae 3-5 part, province of the Yuan Dynasty grass 3-5 part, Herba Selaginellae Involventis 5-12 part, Cryptoporus volvatus (peck) Scnear 5-10 part, Herba Cyperi Glomerati 3-8 part, Herba Gnaphalii Affinis 3-7 part, the imperial root 3-5 part of grass, Herba Loti Corniculati 2-7 part, Radix Primulae sieboldii 3-7 part Herba Rorippae 5-15 part, Herba Wahlenbergiae 5-15 part.
2. one as claimed in claim 1 treats bronchopneumonic pharmaceutical composition, it is characterized in that, by following weight proportioning raw material of Chinese medicine form: Herba Laggerae Alatae 5 parts, Radix Raphani 4 parts, Flos Aglaiae Odoratae spends 3 parts, water Spina jujubae 7 parts, spends Herba Andrographis 8 parts in vain, green pepper Artemisia 5 parts, fruitlet Herba lysimachiae capillipedis 5 Fen ， Rhizoma zingiberis miogae 5 parts, Fols Picridis fuscipilosae 5 parts, province of the Yuan Dynasty grass 3 parts, Herba Selaginellae Involventis 10 parts, Cryptoporus volvatus (peck) Scnear 10 parts, Herba Cyperi Glomerati 7 parts, Herba Gnaphalii Affinis 5 parts, careless imperial root 4 parts, Herba Loti Corniculati 5 parts, Radix Primulae sieboldii 5 Fen ， Herba Rorippae 10 parts, Herba Wahlenbergiae 10 parts.
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| KR102367536B1 (en) * | 2020-10-06 | 2022-02-25 | 동의대학교 산학협력단 | Functional composition for anti-pollution and anti-wrinkle with skin aging improvement effect containing picris hieracioides var. koreana leaf extract |
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| CN102327455A (en) * | 2011-11-01 | 2012-01-25 | 李祥吉 | Traditional Chinese medicine for treating pediatric bronchitis, bronchial pneumonia and asthma |
| CN105194224A (en) * | 2015-10-26 | 2015-12-30 | 闫华 | Pharmaceutical composition for treating nausea and vomiting caused by anaesthesia |
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| KR102367536B1 (en) * | 2020-10-06 | 2022-02-25 | 동의대학교 산학협력단 | Functional composition for anti-pollution and anti-wrinkle with skin aging improvement effect containing picris hieracioides var. koreana leaf extract |
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