CN105343819A - Medicine formula capable of improving skin properties and preparation method thereof - Google Patents

Medicine formula capable of improving skin properties and preparation method thereof Download PDF

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Publication number
CN105343819A
CN105343819A CN201510800987.XA CN201510800987A CN105343819A CN 105343819 A CN105343819 A CN 105343819A CN 201510800987 A CN201510800987 A CN 201510800987A CN 105343819 A CN105343819 A CN 105343819A
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parts
skin
radix
product
skin properties
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张珊
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/52Juglandaceae (Walnut family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/008Preparations for oily skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicine formula capable of improving skin properties. The medicine is composed of the following materials by weight: 2-10 parts of soybean, 1-5 parts of radix sophorae flavescentis, 1-5 parts of radix et rhizoma ginseng, 1-5 parts of cortex dictamni, 1-5 parts of rhizoma zingiberis, 1-5 parts of radix angelicae dahuricae, and 1-5 parts of walnut shells. The medicine formula has original ingredients of materials such as Sophora acid and ginsenosides, etc. and other substances such as ketones, peptides, and phenols, and nutritious substances such as proteins, amino acids, and vitamins, trace elements such as copper, iron, zinc and selenium, etc. The medicine formula has functions for conditioning and changing skin properties, and employs natural edible plant materials which is transformed by edible microbes; the medicine does not use antibiotics and hormones; the medicine formula is an externally applied product, does not do harm to the human body, has high safety, and solves the health safety problem arising from skin therapeutic products usually employing hormones and antibiotics.

Description

A kind of drug formulation and compound method thereof improving skin properties
Technical field
The present invention relates to tcm product field, specifically, relate to a kind of drug formulation and the compound method thereof of improving skin properties.
Background technology
A lot of for the various products of skin health at present, such as: acne removing water, QUBAN SHUANG, MASQUE APAISANT HYDRATANT, skin-tendering cream, whitening cream, Wrinkle eliminating cream etc., but these products are all can only for the solution of Single-issue, as acne removing water just can only treat comedo, QUBAN SHUANG just can only treat mottle, xerosis cutis can only continual use moisturizing product etc., to other skin problems without any effect, and effect that these treatment products do not prevent problem from regenerating, it is exactly simple therapeutical effect, just as a lot of people controls comedo with acne removing water on the market, here cured there to grow again, no end.
Medically know for a long time various skin problem recited above all with skin properties about: the skin oil and fat of oiliness was secreted prosperous, and too much oils and fats can block pore, caused the outburst of small pox, skin sore, indirectly caused pigment calm at skin surface, produced mottle; The skin circulation ability of dryness, skin lack nutrition, can not get moistening, pachylosis, low and deep, corrugate, bad owing to circulating, pigment calmness on skin can be caused equally to get off, produce mottle.Only have neutral skin quality, normal skin metabolism could be maintained, keep normal skin internal recycle and outer circulation, prevent the generation of above-mentioned various skin problem.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of product that skin properties can be transformed into healthy neutral skin quality from oiliness or dryness, is a kind of drug formulation that fundamentally can improve skin properties.
For solving the problem, the technical solution adopted in the present invention is:
Improve a drug formulation for skin properties, it is characterized in that: be made up of the raw material of following weight component: Semen sojae atricolor 2-10 part, Radix Sophorae Flavescentis 1-5 part, Radix Ginseng 1-5 part, Cortex Dictamni 1-5 part, Rhizoma Zingiberis 1-5 part, Radix Angelicae Dahuricae 1-5 part, walnut shell 1-5 part.
Preferably, described a kind of drug formulation improving skin properties is made up of the raw material of following weight component: Semen sojae atricolor 6 parts, Radix Sophorae Flavescentis 3 parts, Radix Ginseng 3 parts, Cortex Dictamni 3 parts, Rhizoma Zingiberis 3 parts, the Radix Angelicae Dahuricae 3 parts, walnut shell 3 parts.
A kind of compound method improving the drug formulation of skin properties of the present invention, comprises the steps:
A, by weight component meter, be broken into smalls by 2-10 part Semen sojae atricolor, 1-5 part Radix Sophorae Flavescentis, 1-5 part Radix Ginseng, 1-5 part Cortex Dictamni, 1-5 part Rhizoma Zingiberis, 1-5 part Radix Angelicae Dahuricae, 1-5 part walnut shell powder, then add 10-200 part clear water wherein, stir;
B, in the above-mentioned raw material mixed, add microorganism fungus kind, and by its in 10-50 DEG C, place 2-20 days under the atmospheric condition of 0.7-1.5, enable microorganism wherein breed and decompose plant material;
C, ambient temperature is mentioned 80-150 DEG C carry out sterilizing;
D, finally product physics and chemistry is become cream state or filter out filter state semi-finished product, according to the final form of product demand, make ointment, medicinal liquid or facial film.
Preferably, vitamin E, hyaluronic acid and other skin-nourishing materials can be added in the ointment in above-mentioned steps d, medicinal liquid or facial film again, make multiple product.
Product of the present invention adopts edible natural plant material, through the product of edible microbial transformation, do not use antibiotic and hormone, product is externally applied product, harmful effect can not be produced to human body, safety is high, and before solving, therapeutic skin products often uses hormone and antibiotic, causes healthy safe problem.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
Improve a drug formulation for skin properties, be made up of the raw material of following weight component: Semen sojae atricolor 2 parts, Radix Sophorae Flavescentis 1 part, Radix Ginseng 1 part, Cortex Dictamni 1 part, Rhizoma Zingiberis 1 part, the Radix Angelicae Dahuricae 1 part, walnut shell 1 part.
Improve a compound method for the drug formulation of skin properties, comprise the steps:
A, by weight component meter, be broken into smalls by 2 portions of Semen sojae atricolor, 1 part of Radix Sophorae Flavescentis, 1 part of Radix Ginseng, 1 part of Cortex Dictamni, 1 part of Rhizoma Zingiberis, 1 part of Radix Angelicae Dahuricae, 1 part of walnut shell powder, then add 20 parts of clear water wherein, stir;
B, in the above-mentioned raw material mixed, add microorganism fungus kind, and be placed on 10-50 DEG C, place 2-20 days under the atmospheric condition of 0.7-1.5, enable microorganism wherein breed and decompose plant material;
C, ambient temperature is mentioned 80-150 DEG C carry out sterilizing;
D, finally product physics and chemistry is become cream state or filter out filter state semi-finished product, according to the final form of product demand, make ointment, medicinal liquid or facial film.
Embodiment 2:
Improve a drug formulation for skin properties, be made up of the raw material of following weight component: Semen sojae atricolor 5 parts, Radix Sophorae Flavescentis 2 parts, Radix Ginseng 1 part, Cortex Dictamni 2 parts, Rhizoma Zingiberis 1 part, the Radix Angelicae Dahuricae 3 parts, walnut shell 2 parts.
5 portions of Semen sojae atricolor, 2 parts of Radix Sophorae Flavescentiss, 1 part of Radix Ginseng, 2 parts of Cortex Dictamni, 1 part of Rhizoma Zingiberis, 3 parts of Radixs Angelicae Dahuricae, 2 parts of walnut shell powders are broken into smalls, then add 120 parts of clear water wherein, stir by a, by weight component meter;
B, in the above-mentioned raw material mixed, add microorganism fungus kind, and be placed on 10-50 DEG C, place 2-20 days under the atmospheric condition of 0.7-1.5, enable microorganism wherein breed and decompose plant material;
C, ambient temperature is mentioned 80-150 DEG C carry out sterilizing;
D, finally product physics and chemistry is become cream state or filter out filter state semi-finished product, according to the final form of product demand, make ointment, medicinal liquid or facial film.
Embodiment 3:
Improve a drug formulation for skin properties, be made up of the raw material of following weight component: Semen sojae atricolor 8 parts, Radix Sophorae Flavescentis 3 parts, Radix Ginseng 3 parts, Cortex Dictamni 3 parts, Rhizoma Zingiberis 1 part, the Radix Angelicae Dahuricae 1 part, walnut shell 2 parts.
8 portions of Semen sojae atricolor, 3 parts of Radix Sophorae Flavescentiss, 3 parts of Radix Ginsengs, 3 parts of Cortex Dictamni, 1 part of Rhizoma Zingiberis, 1 part of Radix Angelicae Dahuricae, 2 parts of walnut shell powders are broken into smalls, then add 175 parts of clear water wherein, stir by a, by weight component meter;
B, in the above-mentioned raw material mixed, add microorganism fungus kind, and be placed on 10-50 DEG C, place 2-20 days under the atmospheric condition of 0.7-1.5, enable microorganism wherein breed and decompose plant material;
C, ambient temperature is mentioned 80-150 DEG C carry out sterilizing;
D, finally product physics and chemistry is become cream state or filter out filter state semi-finished product, according to the final form of product demand, make ointment, medicinal liquid or facial film.
Embodiment 4:
Improve a drug formulation for skin properties, be made up of the raw material of following weight component: Semen sojae atricolor 10 parts, Radix Sophorae Flavescentis 3 parts, Radix Ginseng 1 part, Cortex Dictamni 4 parts, Rhizoma Zingiberis 1 part, the Radix Angelicae Dahuricae 1 part, walnut shell 3 parts.
10 portions of Semen sojae atricolor, 3 parts of Radix Sophorae Flavescentiss, 1 part of Radix Ginseng, 4 parts of Cortex Dictamni, 1 part of Rhizoma Zingiberis, 1 part of Radix Angelicae Dahuricae, 3 parts of walnut shell powders are broken into smalls, then add 200 parts of clear water wherein, stir by a, by weight component meter;
B, in the above-mentioned raw material mixed, add microorganism fungus kind, and be placed on 10-50 DEG C, place 2-20 days under the atmospheric condition of 0.7-1.5, enable microorganism wherein breed and decompose plant material;
C, ambient temperature is mentioned 80-150 DEG C carry out sterilizing;
D, finally product physics and chemistry is become cream state or filter out filter state semi-finished product, according to the final form of product demand, make ointment, medicinal liquid or facial film.
More than for different skin quality or skin problem; to the embodiment that medical material ratio is adjusted; as the crowd that embodiment 4 causes comedo serious for serious oily skin exactly, and other anyly fall into ratio within the scope of raw material weight number of the present invention all in protection scope of the present invention.
The above-mentioned each composition role of the present invention is described below:
Semen sojae atricolor: microbial reproduction existence base stock is the main source of the different yellow trunk of Semen sojae atricolor, vitamin B complex, aminoacid, plant collagen in the present invention.
Radix Sophorae Flavescentis: play removing heat from blood, effect of dispelling spots.
Radix Ginseng: enhancing immunity, conditioning metabolism.
Cortex Dictamni: play antiinflammatory, toxin expelling, whitening function.
Rhizoma Zingiberis: play and invigorate blood circulation, promote skin circulation effect.
The Radix Angelicae Dahuricae: play evacuation of pus granulation promoting, invigorate blood circulation, antiinflammatory, toxin expelling effect.
Walnut shell: play the balanced action of conditioning fat secretion.
Microbial bacteria: 1, decompose plant material, the foster skin conditioning and treating function making product not only have plant material original possessed, also because decompose the secondary substance produced, create new effect, make product of the present invention have the raw materials used change skin properties function originally do not possessed, skin properties can be changed from neutral or oiliness and become neutral skin quality.2, interrupt raw molecule chain, by the natural macromolecular of raw medicinal material, become the micromolecule of free state, such micromolecule just can pass skin surface, enters skin inside, plays due therapeutical effect.
According to analysis display, product of the present invention not only has the original contained composition of raw material, outside the compositions such as such as Radix Sophorae Flavescentis acid, panaquilon, also add multiple trunk, peptide, aldehydes matter, also have nutrient substance and copper, ferrum, zinc, the selenium and other trace elements such as protein, aminoacid, vitamin, contrast experiment proves, just these materials newly increased, and allows product of the present invention have the function of conditioning change skin properties.
The present invention is through following contrast test, and data show:
1., the people of the people of 30 oily skin and 30 dry skins uses not through the face mask cream that the plant material of microbial decomposition is made, and after 30 days, skin properties is without any change.
2., the people of 50 oily skin uses the face mask cream made after microbial decomposition, 32 fuel-displaced obvious minimizings of human face are had after 30 days, after 60 days, everyone is facial fuel-displaced all obviously reduces, show typical neutral skin state, and after inactive product one-year age, still have 35 people can keep neutral skin state, proving that product of the present invention can allow skin be transformed into neutral skin quality really, is not the temporary transient Controlling oil effect of common control oil product.
3., 50 dry skin testers use the same face mask cream made after microbial decomposition, after 30 days, 39 human faces obviously have moisturizing effect, after 60 days all there is obvious moisturizing effect in proprietary face, show typical neutral skin state, and still have 41 people to keep neutral skin state after 1 year stopping using product, showing product of the present invention is not common skin care product, but real change skin properties product.
Above-mentioned oily skin and dry skin tester's is same product, skin products all is at present if it were not for the unidirectional minimizing fat secretion of control oil product, otherwise be exactly moisten product by skin moisturizing, be absolutely not can allowing oily skin reduce fat secretion while, allow again dry skin increase fat secretion, product of the present invention seems antipodal effect by these two kinds and occurs simultaneously.And there is this function just describing product of the present invention and can change skin properties, allow skin properties all become healthy neutral skin quality from oiliness or dryness.
Formula of the present invention and manufacture method are effective utilizations of the key that product efficacy of the present invention realizes, biotechnology microorganism one by one, are key technologies of the present invention.In raw material, Semen sojae atricolor powder can be Semen Glycines or Semen sojae atricolor, can be that raw Semen Glycines powder state adds water also can be ripe bean milk or bean curd state when using as raw material, does not all affect its effect.Except Chinese crude drug listed above, according to treatment needs, other Chinese crude drugs can also be added or in finished product, increase other skin-nourishing materials.
The present invention, on product form, can be liquid, cream state, can make facial film, can be added into wash to protect in product and make multiple product.
To the above-mentioned explanation of the disclosed embodiments, professional and technical personnel in the field are realized or uses the present invention, to be apparent for those skilled in the art to the multiple amendment of these embodiments, General Principle as defined herein can without departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention can not be restricted to these embodiments shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.

Claims (4)

1. can improve a drug formulation for skin properties, it is characterized in that: be made up of the raw material of following weight component: Semen sojae atricolor 2-10 part, Radix Sophorae Flavescentis 1-5 part, Radix Ginseng 1-5 part, Cortex Dictamni 1-5 part, Rhizoma Zingiberis 1-5 part, Radix Angelicae Dahuricae 1-5 part, walnut shell 1-5 part.
2. a kind of drug formulation improving skin properties according to claim 1, is characterized in that: be made up of the raw material of following weight component: Semen sojae atricolor 6 parts, Radix Sophorae Flavescentis 3 parts, Radix Ginseng 3 parts, Cortex Dictamni 3 parts, Rhizoma Zingiberis 3 parts, the Radix Angelicae Dahuricae 3 parts, walnut shell 3 parts.
3. a kind of compound method improving the drug formulation of skin properties according to claim 1, is characterized in that: comprise the steps:
A, by weight component meter, be broken into smalls by 2-10 part Semen sojae atricolor, 1-5 part Radix Sophorae Flavescentis, 1-5 part Radix Ginseng, 1-5 part Cortex Dictamni, 1-5 part Rhizoma Zingiberis, 1-5 part Radix Angelicae Dahuricae, 1-5 part walnut shell powder, then add 10-200 part clear water wherein, stir;
B, in the above-mentioned raw material mixed, add microorganism fungus kind, and by its in 10-50 DEG C, place 2-20 days under the atmospheric condition of 0.7-1.5, enable microorganism wherein breed and decompose plant material;
C, ambient temperature is mentioned 80-150 DEG C carry out sterilizing;
D, finally product physics and chemistry is become cream state or filter out filter state semi-finished product, according to the final form of product demand, make ointment, medicinal liquid or facial film.
4. a kind of compound method improving the drug formulation of skin properties according to claim 3, it is characterized in that: vitamin E, hyaluronic acid and other skin-nourishing materials can be added in the ointment in above-mentioned steps d, medicinal liquid or facial film again, make multiple product.
CN201510800987.XA 2015-11-20 2015-11-20 Medicine formula capable of improving skin properties and preparation method thereof Pending CN105343819A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1265876A (en) * 2000-03-26 2000-09-13 童永良 Skin protective bath bag for baby

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1265876A (en) * 2000-03-26 2000-09-13 童永良 Skin protective bath bag for baby

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘吉华等: "《中药生物技术》", 31 October 2015, 中国医药科技出版社 *
程朝晖等: "《延缓衰老六妙招》", 31 July 2015, 人民军医出版社 *

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Application publication date: 20160224