CN105341919A - Pharmaceutical composition capable of improving memory, and preparation method thereof - Google Patents
Pharmaceutical composition capable of improving memory, and preparation method thereof Download PDFInfo
- Publication number
- CN105341919A CN105341919A CN201510815525.5A CN201510815525A CN105341919A CN 105341919 A CN105341919 A CN 105341919A CN 201510815525 A CN201510815525 A CN 201510815525A CN 105341919 A CN105341919 A CN 105341919A
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- gelatin
- beeswax
- taurine
- preparation
- lecithin
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Links
- 238000002360 preparation method Methods 0.000 title abstract description 10
- 239000008194 pharmaceutical composition Substances 0.000 title abstract description 6
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 42
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims abstract description 34
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 30
- 239000000203 mixture Substances 0.000 claims abstract description 25
- 108010010803 Gelatin Proteins 0.000 claims abstract description 21
- 235000013871 bee wax Nutrition 0.000 claims abstract description 21
- 239000012166 beeswax Substances 0.000 claims abstract description 21
- 229920000159 gelatin Polymers 0.000 claims abstract description 21
- 239000008273 gelatin Substances 0.000 claims abstract description 21
- 235000019322 gelatine Nutrition 0.000 claims abstract description 21
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 21
- 229960003080 taurine Drugs 0.000 claims abstract description 21
- 235000021342 arachidonic acid Nutrition 0.000 claims abstract description 17
- 229940114079 arachidonic acid Drugs 0.000 claims abstract description 17
- CANRESZKMUPMAE-UHFFFAOYSA-L Zinc lactate Chemical compound [Zn+2].CC(O)C([O-])=O.CC(O)C([O-])=O CANRESZKMUPMAE-UHFFFAOYSA-L 0.000 claims abstract description 16
- 229940050168 zinc lactate Drugs 0.000 claims abstract description 16
- 239000011576 zinc lactate Substances 0.000 claims abstract description 16
- 235000000193 zinc lactate Nutrition 0.000 claims abstract description 16
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims abstract description 15
- 235000011187 glycerol Nutrition 0.000 claims abstract description 15
- 235000010445 lecithin Nutrition 0.000 claims abstract description 15
- 229940067606 lecithin Drugs 0.000 claims abstract description 15
- 239000000787 lecithin Substances 0.000 claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000007901 soft capsule Substances 0.000 claims abstract description 13
- 239000004480 active ingredient Substances 0.000 claims abstract description 10
- 239000008213 purified water Substances 0.000 claims abstract description 9
- 239000002775 capsule Substances 0.000 claims abstract description 8
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims description 10
- 235000020778 linoleic acid Nutrition 0.000 claims description 10
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 8
- 238000000746 purification Methods 0.000 claims description 6
- 230000000694 effects Effects 0.000 abstract description 8
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 abstract description 7
- SBJKKFFYIZUCET-JLAZNSOCSA-N Dehydro-L-ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(=O)C1=O SBJKKFFYIZUCET-JLAZNSOCSA-N 0.000 abstract description 6
- 235000020669 docosahexaenoic acid Nutrition 0.000 abstract description 6
- 230000036541 health Effects 0.000 abstract description 5
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 9
- 230000005611 electricity Effects 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 239000008279 sol Substances 0.000 description 5
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 4
- 229940092738 beeswax Drugs 0.000 description 4
- 210000004556 brain Anatomy 0.000 description 4
- 229910052802 copper Inorganic materials 0.000 description 4
- 239000010949 copper Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 239000011701 zinc Substances 0.000 description 3
- 229910052725 zinc Inorganic materials 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 description 2
- 229960002986 dinoprostone Drugs 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 238000003304 gavage Methods 0.000 description 2
- 235000020256 human milk Nutrition 0.000 description 2
- 210000004251 human milk Anatomy 0.000 description 2
- 230000002028 premature Effects 0.000 description 2
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 description 2
- KAQKFAOMNZTLHT-OZUDYXHBSA-N prostaglandin I2 Chemical compound O1\C(=C/CCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-OZUDYXHBSA-N 0.000 description 2
- 210000001525 retina Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 2
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 description 1
- ADVPTQAUNPRNPO-REOHCLBHSA-N 3-sulfino-L-alanine Chemical compound OC(=O)[C@@H](N)C[S@@](O)=O ADVPTQAUNPRNPO-REOHCLBHSA-N 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 235000021294 Docosapentaenoic acid Nutrition 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 101100246038 Mus musculus Ptpn5 gene Proteins 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- ADVPTQAUNPRNPO-UHFFFAOYSA-N alpha-amino-beta-sulfino-propionic acid Natural products OC(=O)C(N)CS(O)=O ADVPTQAUNPRNPO-UHFFFAOYSA-N 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000024245 cell differentiation Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 210000003792 cranial nerve Anatomy 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000009189 diving Effects 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 150000002066 eicosanoids Chemical class 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 229960001123 epoprostenol Drugs 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 125000005456 glyceride group Chemical group 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 150000002617 leukotrienes Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 230000005709 nerve cell growth Effects 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 1
- 230000036417 physical growth Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 230000010118 platelet activation Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 235000015170 shellfish Nutrition 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention provides a pharmaceutical composition capable of improving memory, and a preparation method thereof. Active ingredients of the pharmaceutical composition comprise, by weight, 5 to 15 parts of DHA, 10 to 30 parts of arachidonic acid, 0.3 to 0.9 part of zinc lactate, 3 to 7 parts of taurine, 15 to 30 parts of linoleic acid, and 0.2 to 0.4 part of lecithin. According to the preparation method, the active ingredients and beeswax are grinded and mixed, and an obtained mixture is taken as capsule cores; gelatin, glycerin, and purified water are mixed so as to prepare a colloidal sol; the colloidal sol is subjected to pelleting so as to obtain soft capsules. According to the preparation method, DHA, arachidonic acid, zinc lactate, taurine, linoleic acid, and lecithin are combined, synergistic effects are achieved, health care effect is improved, and memory is improved.
Description
Technical field
The present invention relates to a kind of health products, specifically relate to a kind of pharmaceutical composition of Improving memory power, the invention still further relates to the preparation method of this pharmaceutical composition.
Background technology
DHA, DHA, is commonly called as docosapentaenoic acid, is a kind of to the very important unrighted acid of human body, belongs to the important member in omega-3 unsaturated fatty acid family.A kind of main component that DHA is nervous system cell growth and maintains, be brain and amphiblestroid important composition composition, in human brain cortex, content is up to 20%, in eye retina, proportion is maximum, account for 50%, therefore, to tire infant intelligence and visual acuity most important.
Arachidonic acid, it is all-cis formula-5,8,11,14-eicosatetraenoic acid, chemical formula is as follows: CH3 (CH2) 4 (CH=CH-CH2) 4 (CH2) 2COOH, belong to unrighted acid, wherein containing four carbon-to-carbon double bonds, a carbon-oxygen double bond is higher unsaturated fatty acid.Be distributed widely in the animal kingdom, be present on a small quantity in certain glyceride of planting, also can find in glycerophosphatide class.Arachidonic acid, the bioactivator of many circulation eicosanoid derivatives, as PGE2 (PGE2), prostacyclin (PGI2), thromboxane element A2 (TXA2) and the direct precursor of leukotrienes and C4 (LTC4).The metabolism of these biological active matter confrontation lipid proteins, Hemorheology, blood vessel elasticity, leukocyte function and platelet activation etc. have important regulating action.
Zinc is one of trace element of needed by human, plays an important role in the important physiology courses such as growth in humans's growth, reproduction heredity, immunity, endocrine.Zinc lactate is a kind of well food zinc enhancer, and have important effect to baby and teen-age intelligence and body development, assimilation effect is better than inorganic zinc.
The rich content of taurine in brain, widely distributed, can obviously promote neural grow and cell proliferation, differentiation, and in dose dependent, to play an important role in cranial nerve cell growth course.Research shows: the content of taurine in premature's brain is starkly lower than term infant; this is because the cysteine sulfinic acid dehydrogenase (CSAD) in premature's body is not yet reached maturity; synthesizing taurine is not enough to the needs meeting body, need be supplemented by breast milk.Content of taurine in breast milk is higher, and especially just Ruzhong content is higher.If supplement not enough, physical growth of children will be made to grow slow, MR.The growth of the nervous centralis of taurine and child, fetus and retina etc. has close relationship, and milk simple is for a long time fed, and easily causes the shortage of taurine.
Mentioned component widely uses in health products as active material, but different activities composition needs to carry out reasonably combinedly could effectively play respective effect.Up to the present, field of health care products has had the product of many Improving memory power, but effect is still not fully up to expectations, needs to be improved further.
Summary of the invention
The present invention is directed to the composition that above-mentioned deficiency provides a kind of Improving memory power, the present invention also provides the method preparing described composition.
For achieving the above object, technical scheme of the present invention is as follows:
A composition for Improving memory, its active ingredient is grouped into by the one-tenth of following weight portion: DHA5-15, arachidonic acid 10-30, zinc lactate 0.3-0.9, taurine 3-7, linoleic acid 15-30, lecithin 0.2-0.4.
Preferably, its active ingredient is grouped into by the one-tenth of following weight portion: DHA10, arachidonic acid 20, zinc lactate 0.6, taurine 5, linoleic acid 20, lecithin 0.33.
Above-mentioned composition can be prepared into pharmaceutically acceptable various formulation, includes but not limited to soft capsule, pill, tablet, pulvis.
Preferred described formulation is soft capsule, and described soft capsule is made up of beeswax, gelatin, G & W and described active ingredient.
Preferably, the weight portion of described beeswax, gelatin, G & W is: beeswax 1-3, gelatin 10-15, glycerine 3-7, purified water 10-15.In one embodiment of the invention, the weight portion of described beeswax, gelatin, G & W is: beeswax 1.58, gelatin 12, glycerine 4.8, purified water 12.
Prepare a method for above-mentioned composition, its be using described active ingredient and beeswax ground and mixed as the capsule heart, gelatin, glycerin purification water are mixed and made into colloidal sol, pelleting, obtain soft capsule.
The present invention, by combined to DHA, arachidonic acid, zinc lactate, taurine, linoleic acid, lecithin, find to there occurs synergy between them, effectively improves health-care effect, Improving memory power.
Detailed description of the invention
Following examples further illustrate content of the present invention, but should not be construed as limitation of the present invention.Without departing from the spirit and substance of the case in the present invention, the amendment do the inventive method, step or condition or replacement, all belong to scope of the present invention.
If do not specialize, the conventional means that technological means used in embodiment is well known to those skilled in the art.
The composition and method of making the same of embodiment 1 one kinds of Improving memory power
Formula: DHA10kg, arachidonic acid 20kg, zinc lactate 0.6kg, taurine 5kg, linoleic acid 20kg, lecithin 0.33kg, beeswax 1.58kg, gelatin 12kg, glycerine 4.8kg, purified water 12kg.
Its preparation method is as follows: using DHA, arachidonic acid, zinc lactate, taurine, linoleic acid, lecithin, beeswax ground and mixed as the capsule heart, and gelatin, glycerin purification water are mixed and made into colloidal sol, pelleting, and conveniently technique obtains soft capsule.
The composition and method of making the same of embodiment 2 one kinds of Improving memory power
Formula: DHA15kg, arachidonic acid 30kg, zinc lactate 0.3kg, taurine 7kg, linoleic acid 30kg, lecithin 0.4kg, beeswax 3kg, gelatin 15kg, glycerine 7kg, purified water 15kg.
Its preparation method is as follows: using DHA, arachidonic acid, zinc lactate, taurine, linoleic acid, lecithin, beeswax ground and mixed as the capsule heart, and gelatin, glycerin purification water are mixed and made into colloidal sol, pelleting, and conveniently technique obtains soft capsule.
The composition and method of making the same of embodiment 3 one kinds of Improving memory power
Formula: DHA5kg, arachidonic acid 10kg, zinc lactate 0.9kg, taurine 3kg, linoleic acid 10kg, lecithin 0.2kg, beeswax 1kg, gelatin 10kg, glycerine 3kg, purified water 10kg.
Its preparation method is as follows: using DHA, arachidonic acid, zinc lactate, taurine, linoleic acid, lecithin, beeswax ground and mixed as the capsule heart, and gelatin, glycerin purification water are mixed and made into colloidal sol, pelleting, and conveniently technique obtains soft capsule.
The composition and method of making the same of embodiment 4 one kinds of Improving memory power
Formula: DHA10kg, arachidonic acid 18kg, zinc lactate 0.45kg, taurine 2kg, linoleic acid 12kg, lecithin 0.3kg, beeswax 2kg, gelatin 12.5kg, glycerine 5kg, purified water 12.5kg.
Its preparation method is as follows: using DHA, arachidonic acid, zinc lactate, taurine, linoleic acid, lecithin, beeswax ground and mixed as the capsule heart, and gelatin, glycerin purification water are mixed and made into colloidal sol, pelleting, and conveniently technique obtains soft capsule.
Embodiment 5 health products effect detection
1, mouse step down test
The experimental provision of step dow n test is a rectangle reflective box, and its major diameter is divided into some intervals by black plastic plate, and bottom paving take spacing as the copper grid of 5mm, can lead to suitable electric current (32V alternating current).Each little interval has a high and diameter to be the chain-wales of 4.5cm.During experiment, first mouse is placed on copper grid, when copper grid are energized, the mouse jumped on copper grid is shocked by electricity, its normal reaction hides electric shock to jump onto platform, and most mouse likely again or repeatedly jumps off platform and shocked by electricity, and can snap back again when being subject to shocking by electricity platform.Training 5min like this, and the number of times (errors number) recording that every mouse shocked by electricity, as school grade.Again test after 24h, when this is test, first mouse is placed on diving tower, the errors number in the time (incubation period) that record jumps off for the first time, the number of animals shocked by electricity and 5min, reflect memory maintenance situation with this.
Experiment and grouping: the composition prepared according to embodiment 1-4 is experimental group 1-4, to prepare according to embodiment 1 but the composition do not obtained containing linoleic acid is test group 5, linoleic acid is experimental group 6, and commercially available also shellfish soothing soft capsule is experimental group 7, and the blank capsule casing material of embodiment 1 is experimental group 8.Often organize 10 mouse.After mouse conforms, every mouse measures gavage according to 25mg/kg, and control group gives 0.1ml physiological saline gavage.Step down test is carried out with administration respectively after 24 hours before administration.
Result is as shown in the table
2, clinical testing
The composition of embodiment 1 is each according to 1200mg, provide for 3 times every day 30-40 year adult, continuous 7 days, be divided into two groups often to organize 10 people, control group gives blank, carries out Blind Test.Memory state before and after record test, result experimental group self-induction memory is obviously improved, and control group does not have significant change.
Claims (7)
1. a composition for Improving memory, its active ingredient is grouped into by the one-tenth of following weight portion: DHA5-15, arachidonic acid 10-30, zinc lactate 0.3-0.9, taurine 3-7, linoleic acid 15-30, lecithin 0.2-0.4.
2. composition according to claim 1, is characterized in that, its active ingredient is grouped into by the one-tenth of following weight portion: DHA10, arachidonic acid 20, zinc lactate 0.6, taurine 5, linoleic acid 20, lecithin 0.33.
3. composition according to claim 1 and 2, it is soft capsule.
4. composition according to claim 3, is characterized in that, soft capsule described in it is made up of beeswax, gelatin, G & W and described active ingredient.
5. composition according to claim 4, is characterized in that, the weight portion of described beeswax, gelatin, G & W is: beeswax 1-3, gelatin 10-15, glycerine 3-7, purified water 10-15.
6. composition according to claim 5, is characterized in that, the weight portion of described beeswax, gelatin, G & W is: beeswax 1.58, gelatin 12, glycerine 4.8, purified water 12.
7. prepare a method for composition described in any one of claim 1-6, it is characterized in that, using described active ingredient and beeswax ground and mixed as the capsule heart, gelatin, glycerin purification water are mixed and made into colloidal sol, pelleting, obtain soft capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510815525.5A CN105341919B (en) | 2015-11-23 | 2015-11-23 | A kind of pharmaceutical composition for improving memory and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510815525.5A CN105341919B (en) | 2015-11-23 | 2015-11-23 | A kind of pharmaceutical composition for improving memory and preparation method thereof |
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| Publication Number | Publication Date |
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| CN105341919A true CN105341919A (en) | 2016-02-24 |
| CN105341919B CN105341919B (en) | 2018-05-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201510815525.5A Active CN105341919B (en) | 2015-11-23 | 2015-11-23 | A kind of pharmaceutical composition for improving memory and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108783294A (en) * | 2018-05-24 | 2018-11-13 | 哈福科技（武汉）集团有限公司 | A kind of functional food and preparation method thereof improving memory |
| CN113519848A (en) * | 2021-07-28 | 2021-10-22 | 宁波天皓生物科技有限公司 | Processing method of DHA algae oil and ARA composition product |
| CN115192628A (en) * | 2022-08-24 | 2022-10-18 | 辽宁华康星辰医药科技有限公司 | Composition and preparation with memory enhancing effect and preparation method thereof |
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|---|---|---|---|---|
| WO2007128801A1 (en) * | 2006-05-08 | 2007-11-15 | Novartis Ag | Combination of organic compounds |
| CN101965875A (en) * | 2010-10-12 | 2011-02-09 | 李国勇 | Milk powder for improving children intelligence |
| CN103211022A (en) * | 2013-04-24 | 2013-07-24 | 江西雄鹰乳业有限公司 | Intelligence reinforcing milk powder for children |
| CN103989184A (en) * | 2014-06-08 | 2014-08-20 | 宁波市成大机械研究所 | Algal oil soft capsule containing arachidonic acid |
-
2015
- 2015-11-23 CN CN201510815525.5A patent/CN105341919B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007128801A1 (en) * | 2006-05-08 | 2007-11-15 | Novartis Ag | Combination of organic compounds |
| CN101965875A (en) * | 2010-10-12 | 2011-02-09 | 李国勇 | Milk powder for improving children intelligence |
| CN103211022A (en) * | 2013-04-24 | 2013-07-24 | 江西雄鹰乳业有限公司 | Intelligence reinforcing milk powder for children |
| CN103989184A (en) * | 2014-06-08 | 2014-08-20 | 宁波市成大机械研究所 | Algal oil soft capsule containing arachidonic acid |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108783294A (en) * | 2018-05-24 | 2018-11-13 | 哈福科技（武汉）集团有限公司 | A kind of functional food and preparation method thereof improving memory |
| CN113519848A (en) * | 2021-07-28 | 2021-10-22 | 宁波天皓生物科技有限公司 | Processing method of DHA algae oil and ARA composition product |
| CN115192628A (en) * | 2022-08-24 | 2022-10-18 | 辽宁华康星辰医药科技有限公司 | Composition and preparation with memory enhancing effect and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105341919B (en) | 2018-05-01 |
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