CN105339486B - 用于呼吸样本收集和分析的系统 - Google Patents

用于呼吸样本收集和分析的系统 Download PDF

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Publication number
CN105339486B
CN105339486B CN201480023820.0A CN201480023820A CN105339486B CN 105339486 B CN105339486 B CN 105339486B CN 201480023820 A CN201480023820 A CN 201480023820A CN 105339486 B CN105339486 B CN 105339486B
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CN
China
Prior art keywords
sample
collection system
particle
biological specimen
specimen collection
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Expired - Fee Related
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CN201480023820.0A
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English (en)
Chinese (zh)
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CN105339486A (zh
Inventor
P·希思利安
R·纳斯尔
L·鲁赫德
S·A·查普曼
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DETON CORP
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DETON CORP
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0816—Joints or connectors
    • A61M16/0841—Joints or connectors for sampling
    • A61M16/085—Gas sampling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/201—Controlled valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/208—Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B2010/0083—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements for taking gas samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B2010/0083—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements for taking gas samples
    • A61B2010/0087—Breath samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A61M2205/123—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7545—General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N2001/2244—Exhaled gas, e.g. alcohol detecting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201480023820.0A 2013-03-12 2014-03-12 用于呼吸样本收集和分析的系统 Expired - Fee Related CN105339486B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361778360P 2013-03-12 2013-03-12
US61/778,360 2013-03-12
US201361916159P 2013-12-14 2013-12-14
US61/916,159 2013-12-14
PCT/US2014/024682 WO2014165184A1 (en) 2013-03-12 2014-03-12 System for breath sample collection and analysis

Publications (2)

Publication Number Publication Date
CN105339486A CN105339486A (zh) 2016-02-17
CN105339486B true CN105339486B (zh) 2018-12-21

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Family Applications (1)

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Country Status (5)

Country Link
US (1) US10080857B2 (cg-RX-API-DMAC10.html)
EP (1) EP2970858A4 (cg-RX-API-DMAC10.html)
JP (1) JP2016512431A (cg-RX-API-DMAC10.html)
CN (1) CN105339486B (cg-RX-API-DMAC10.html)
WO (1) WO2014165184A1 (cg-RX-API-DMAC10.html)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9988691B2 (en) 2010-07-06 2018-06-05 Deton Corp. System for airborne bacterial sample collection and analysis
US20120226183A1 (en) * 2010-08-30 2012-09-06 Quintron Instrument Company Evacuated air chamber
WO2014165184A1 (en) 2013-03-12 2014-10-09 Deton Corp. System for breath sample collection and analysis
CA2850998A1 (en) * 2014-04-18 2015-10-18 Thc Breathalyzer, Inc. Cannabis drug detection device
JP2017527822A (ja) 2014-06-27 2017-09-21 パルス ヘルス エルエルシー 蛍光検出アセンブリ
CN106796217A (zh) * 2014-07-21 2017-05-31 泰克年研究发展基金会公司 用于直接呼吸采样的组合物
US10226201B2 (en) 2015-10-29 2019-03-12 Invoy Holdings, Llc Flow regulation device for breath analysis and related method
GB2548122B (en) * 2016-03-08 2018-09-12 Univ Of Northumbria At Newcastle Exhaled breath condensate collection device and a kit of parts therefor
WO2017187120A1 (en) * 2016-04-25 2017-11-02 Owlstone Medical Limited Systems and device for capturing breath samples
CN106053387B (zh) * 2016-06-29 2019-04-23 南京青辰光电科技有限公司 一种呼出气体检测方法及装置
EP3336515B1 (en) * 2016-12-14 2022-05-11 Airbus Defence and Space GmbH Hand-held air sampler, including filter magazine for storing and positioning filter elements
DE102017209909A1 (de) * 2017-06-13 2018-12-13 Robert Bosch Gmbh Mundstück, System und Verfahren für eine Freigabe einer Messung von Analyten in Ausatemluft
SE541748C2 (en) 2017-07-10 2019-12-10 Pexa Ab System for collecting exhaled particles
CN108048296B (zh) * 2017-11-02 2021-06-11 暨南大学 微生物实时分离检测方法及分离检测装置在微生物分离检测鉴定中的应用
WO2019178247A1 (en) * 2018-03-15 2019-09-19 Biolum Sciences Llc Sensor devices and systems for monitoring markers in breath
FR3083612B1 (fr) * 2018-07-04 2021-06-04 Commissariat Energie Atomique Dispositif de collecte de particules
DE102018212411A1 (de) * 2018-07-25 2020-01-30 Robert Bosch Gmbh Verfahren zur Gewinnung einer Atemprobe eines Probanden und Vorrichtung
NL2021637B1 (en) 2018-09-14 2020-05-07 Stichting Katholieke Univ Breath sampler
CN117883121A (zh) 2019-08-26 2024-04-16 泽特奥科技公司 利用呼出气诊断结核病和其他疾病
CN111544000B (zh) * 2019-10-01 2024-08-20 华中科技大学同济医学院附属协和医院 咳嗽能力评估仪
CN110934589A (zh) * 2019-12-03 2020-03-31 西北工业大学 一种呼吸道病毒的检测装置及检测方法
US12364411B2 (en) 2020-04-03 2025-07-22 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
US11839463B2 (en) 2020-04-03 2023-12-12 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
US10952812B1 (en) 2020-04-24 2021-03-23 Inquis Medical, Inc. Devices, systems, and methods for protecting healthcare workers from airborne pathogens
US11000655B1 (en) * 2020-04-24 2021-05-11 Inquis Medical, Inc. Devices, systems, and methods for protecting healthcare workers from airborne pathogens
US12196672B2 (en) 2020-05-07 2025-01-14 Hand Held Products, Inc. Apparatuses, systems, and methods for sample testing
US12498328B2 (en) 2020-05-07 2025-12-16 Hand Held Products, Inc. Apparatuses, systems, and methods for sample testing
US12553885B2 (en) 2020-05-07 2026-02-17 Hand Held Products, Inc. Apparatuses, systems, and methods for sample testing
CN116134128B (zh) 2020-05-26 2026-08-04 3M创新有限公司 用于测试无生命表面、群体和个体的病原体感染的组合物、装置和方法
EP3936044B1 (en) * 2020-07-06 2024-12-18 Dräger Safety AG & Co. KGaA Sample collector for receiving a breath gas sample and gas sample testing device
US11207057B1 (en) 2020-08-07 2021-12-28 Cyrano Medical, Inc. Nasopharyngeal sample collection devices and methods
WO2022046902A1 (en) * 2020-08-25 2022-03-03 University Of Tennessee Research Foundation Breath collector and method for diagnosis and/or monitoring
CA3194305A1 (en) * 2020-09-30 2022-04-07 David Geoffrey Vince Rapid test system for viral and bacterial infections
EP4228725A4 (en) 2020-10-15 2024-11-06 Proveris Scientific Corporation SYSTEMS AND METHODS FOR INHALATOR TESTING
US11846574B2 (en) * 2020-10-29 2023-12-19 Hand Held Products, Inc. Apparatuses, systems, and methods for sample capture and extraction
WO2022099087A1 (en) * 2020-11-05 2022-05-12 President And Fellows Of Harvard College An airborne pathogen diagnostic platform
JP7877332B2 (ja) * 2021-02-11 2026-06-22 スリーエム イノベイティブ プロパティズ カンパニー バイオエアロゾル試料を収集及び分析するためのデバイス及び方法
US12672795B2 (en) 2021-03-31 2026-07-07 Zeteo Tech, Inc. Capturing truncated proteoforms in exhaled breath for diagnosis of tuberculosis
KR102790377B1 (ko) 2021-03-31 2025-04-02 제테오 테크, 인코포레이티드 인공호흡기를 이용하여 호흡하는 환자를 모니터링하기위한 호기 수집 시스템 및 방법
WO2022208359A1 (en) * 2021-04-02 2022-10-06 3M Innovative Properties Company Sample collection device and method
US20240188847A1 (en) * 2021-04-19 2024-06-13 Imec Vzw A sample collector
WO2022234044A1 (en) * 2021-05-05 2022-11-10 Avelo Ag Device, system and method for collecting and eluting aerosol particles from human breaths for analysis
US20240341628A1 (en) * 2021-07-22 2024-10-17 3M Innovative Properties Company Sample collection device and system
JP2024529626A (ja) * 2021-07-22 2024-08-08 スリーエム イノベイティブ プロパティズ カンパニー 保護されたサンプル収集媒体
US20240369464A1 (en) * 2021-08-22 2024-11-07 Pneumax, Llc Systems and methods for real-time analysis of inhaled particles
EP4166924A3 (en) * 2021-09-24 2023-06-07 Hand Held Products, Inc. Apparatuses, systems, and methods for sample capture and extraction
WO2023205584A1 (en) * 2022-04-18 2023-10-26 Infinity Biologix Llc Systems for the collection of viral particles and uses thereof
US20230337938A1 (en) * 2022-04-22 2023-10-26 Breathonix Pte. Ltd. Method and apparatus to ensure biosafety by filtering exhaled breath waste during breath sampling
WO2024077040A1 (en) * 2022-10-05 2024-04-11 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Device for collecting exhaled aerosols during mechanical ventilation
WO2024089183A1 (en) 2022-10-27 2024-05-02 Avelo Ag Device and system for collecting aerosol particles and preparing the sample for analysis

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0302681A2 (en) * 1987-08-07 1989-02-08 Lion Technology Limited Fluid sampling systems
CN1676173A (zh) * 2004-03-31 2005-10-05 爱特玛医药股份公司 用于分析呼吸气体的设备
CN101379388A (zh) * 2006-02-03 2009-03-04 大塚制药株式会社 呼出气体测定分析方法及装置
CN101466436A (zh) * 2006-04-12 2009-06-24 普马特里克斯公司 测定颗粒产生的诊断装置
CN101742964A (zh) * 2007-06-27 2010-06-16 皇家飞利浦电子股份有限公司 用于分析呼吸系统的发炎状态的装置
CN102264404A (zh) * 2008-12-23 2011-11-30 美国政府卫生和公众服务部疾病预防和控制中心 肺部浮质收集装置
WO2012006250A1 (en) * 2010-07-06 2012-01-12 Deton Corp. System for airborne bacterial sample collection and analysis
CN102498398A (zh) * 2009-09-09 2012-06-13 森撒部伊斯公司 呼出气中的药物检测
CN102596029A (zh) * 2009-10-22 2012-07-18 皇家飞利浦电子股份有限公司 用于测量呼出空气中气体的浓度的方法和设备
WO2012120140A1 (en) * 2011-03-09 2012-09-13 Sensa Bues Ab A portable sampling device and method for sampling drug substances from exhaled breath

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3760831A (en) 1971-11-01 1973-09-25 Ford Motor Co Gas flow control system for an analytical instrument
US3858573A (en) 1973-07-09 1975-01-07 Said Ryan By Said Williams Alveolar gas trap and method of use
US3880591A (en) 1974-01-02 1975-04-29 Borg Warner Mouthpiece for breath testing devices
US4133202A (en) 1977-04-22 1979-01-09 The Regents Of The University Of Minnesota Multiple nozzle single stage impactor
CA1143179A (en) 1978-11-03 1983-03-22 Thomas P. Jones Gas sampling devices
US4572208A (en) 1983-06-29 1986-02-25 Utah Medical Products, Inc. Metabolic gas monitoring apparatus and method
FR2557295B1 (fr) 1983-12-23 1986-03-28 Commissariat Energie Atomique Echantillonneur d'aerosols a impaction en cascade et a depot uniforme
US4558708A (en) 1984-10-24 1985-12-17 Tri-Med, Inc. Patient's airway adapter to withdraw a patient's gas samples for testing free of sputum mucus and/or condensed water, by utilizing a hollow cylindrical hydrophobic liquid baffle
US4678488A (en) 1985-05-02 1987-07-07 Sensors, Inc. Liquid separator for gas analyzer
US5081871A (en) 1989-02-02 1992-01-21 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Breath sampler
US5253641A (en) 1989-12-01 1993-10-19 Choate Thomas V Respiratory filter apparatus and method
US5046491A (en) 1990-03-27 1991-09-10 Derrick Steven J Apparatus and method for respired gas collection and analysis
US5042501A (en) 1990-05-01 1991-08-27 Battelle Memorial Institute Apparatus and method for analysis of expired breath
US5211181A (en) 1991-05-17 1993-05-18 Martek Corporation Apparatus and method for collecting human breath samples
US5372126A (en) 1992-09-14 1994-12-13 Blau; Anthony D. Pulmonary sampling chamber
US5409014A (en) 1993-08-13 1995-04-25 Dravon Medical, Inc. Fluid meter
JPH07116145A (ja) 1993-10-25 1995-05-09 Kyoto Daiichi Kagaku:Kk 呼気採取装置
JP3838671B2 (ja) 1993-10-25 2006-10-25 アークレイ株式会社 呼気採取装置
US5465728A (en) 1994-01-11 1995-11-14 Phillips; Michael Breath collection
JPH0854389A (ja) 1994-08-09 1996-02-27 Suzuki Motor Corp 呼気採取装置
US5787885A (en) 1994-10-13 1998-08-04 Lemelson; Jerome H. Body fluid analysis system
DE19545794C2 (de) 1995-12-08 1998-03-19 Draegerwerk Ag Gasprobenahmesystem mit einem Mundstück
US5826577A (en) 1996-01-30 1998-10-27 Bacharach, Inc. Breath gas analysis module
US5855652A (en) 1997-01-31 1999-01-05 Topaz 2000, Inc. Aerosol collector and concentrator
DE19718924A1 (de) 1997-04-28 1998-10-29 Medium Sensor Gmbh Vorrichtung zur Gewinnung von Inhaltsstoffen der Ausatemluft sowie Verfahren zur Isolierung der Inhaltsstoffe und deren Verwendung
US5902385A (en) 1997-06-23 1999-05-11 Skc, Inc. Swirling aerosol collector
US5904752A (en) 1997-06-23 1999-05-18 Skc, Inc. Method for collecting airborne particles and microorganisms by their injection into a swirling air flow
US6217636B1 (en) 1998-03-13 2001-04-17 The Texas A&M University System Transpirated wall aerosol collection system and method
SE9801532D0 (sv) 1998-04-30 1998-04-30 Aerocrine Ab Device for the collection of exhaled air samples
US6729196B2 (en) * 1999-03-10 2004-05-04 Mesosystems Technology, Inc. Biological individual sampler
US7578973B2 (en) 1998-11-13 2009-08-25 Mesosystems Technology, Inc. Devices for continuous sampling of airborne particles using a regenerative surface
US6585661B1 (en) 1998-12-18 2003-07-01 University Of Virginia Patent Foundation Device and method for monitoring asthma
US6053874A (en) 1999-01-25 2000-04-25 Boditech Diagnostics Limited Breath collection and storage
US6468330B1 (en) 1999-06-14 2002-10-22 Innovatek, Inc. Mini-cyclone biocollector and concentrator
GB0015309D0 (en) 2000-06-21 2000-08-16 Djupesland Per G Apparatus
US6732569B2 (en) 2001-01-25 2004-05-11 University Of Maryland System and method for collecting samples of atmospheric aerosol particles for near-real time analysis
WO2002084266A2 (en) * 2001-04-11 2002-10-24 Rapid Biosensor Systems Limited Biological measurement system
CA2383856A1 (en) 2001-04-27 2002-10-27 Bombardier, Inc. Fluid reservoir
US7118537B2 (en) 2001-04-30 2006-10-10 Respiratory Research, Inc. Method and device for collecting and analyzing exhaled breath
US6582376B2 (en) 2001-09-13 2003-06-24 Pranalytica, Inc. Alveolar breath collection device and method
US20030162204A1 (en) 2001-12-04 2003-08-28 Dave Smith Alcohol detection assembly
US6726637B2 (en) 2001-12-06 2004-04-27 Michael Phillips Breath collection apparatus
WO2003064994A2 (en) 2002-01-29 2003-08-07 Talton James D Methods of collecting and analyzing human breath
US6520034B1 (en) 2002-04-03 2003-02-18 The Regents Of The University Of California High air volume to low liquid volume aerosol collector
WO2004023997A1 (en) * 2002-09-16 2004-03-25 Aerocrine Ab Apparatus and method for diagnostic gas analysis
US6854344B2 (en) 2002-12-19 2005-02-15 The Johns Hopkins University Sample retrieval device for aerosol collection
AU2003299850A1 (en) 2002-12-20 2004-07-22 Amidex, Inc. Breath aerosol collection system and method
WO2004073497A2 (en) 2003-02-14 2004-09-02 The Charlotte-Mecklenburg Hospital Authority Device and method for collection of exhaled alveolar breath condensate
US20050085740A1 (en) 2003-04-01 2005-04-21 Davis Cristina E. Non-invasive breath analysis using field asymmetric ion mobility spectrometry
US7101341B2 (en) 2003-04-15 2006-09-05 Ross Tsukashima Respiratory monitoring, diagnostic and therapeutic system
US7282032B2 (en) 2003-06-03 2007-10-16 Miller Thomas P Portable respiratory diagnostic device
US7073402B2 (en) 2003-08-12 2006-07-11 Skc, Inc. Air sampler with parallel impactors
WO2007001342A2 (en) 2004-08-20 2007-01-04 University Of Virginia Patent Foundation Exhaled breath condensate collection and assay system and method
US8627821B2 (en) 2005-01-10 2014-01-14 Pulmatrix, Inc. Method and device for decreasing contamination
US20060178592A1 (en) 2005-02-07 2006-08-10 Aperson Biosystems Corp. System and method for controlling the flow of exhaled breath during analysis
JP5059740B2 (ja) 2005-02-09 2012-10-31 エス３アイ， エル エル シィ 粒子を検出、分類及び同定する方法及びシステム
WO2007020640A2 (en) 2005-08-16 2007-02-22 Oridion Medical 1987, Ltd. Breath sampling device and method for using same
US20070235100A1 (en) 2005-10-12 2007-10-11 Arrowhead Products Corporation Double walled, self-insulating, lightweight duct
EP2104451A4 (en) 2006-01-25 2010-01-06 Pipex Inc DROPLET COLLECTION DEVICES AND METHODS FOR DETECTING AND CONTROLLING AIR-TRANSMISSIBLE DISEASES USING AN RFID
US8002712B2 (en) 2006-01-26 2011-08-23 Meka Vikas V Breath and breath condensate analysis system and associated methods
US7779840B2 (en) 2006-06-21 2010-08-24 General Electric Company Ventilator breath condensate sampler and method of collecting a breath condensate sample
US7631567B1 (en) 2006-08-18 2009-12-15 The United States Of America As Represented By The Secretary Of The Army Systems and methods for collecting particles from a large volume of gas into a small volume of liquid
WO2008156471A1 (en) 2006-12-13 2008-12-24 Stc.Unm Non-invasive rapid diagnostic test for m. tuberculosis infection
US8313440B2 (en) 2008-01-22 2012-11-20 Mitchell Friedman Infant breath collector
WO2009150134A1 (de) 2008-06-09 2009-12-17 Boehringer Ingelheim International Gmbh Vorrichtung und verfahren zur ermittlung der eigenschaften von aerosolformulierungen
TWI367258B (en) * 2008-12-24 2012-07-01 Univ Kaohsiung Medical Quantitative sampler of exhaled pathogens and quantitative analysis method using the same
US20110105856A1 (en) 2009-10-29 2011-05-05 Robyn Aylor Haines Diagnostic testing
WO2014165184A1 (en) 2013-03-12 2014-10-09 Deton Corp. System for breath sample collection and analysis

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0302681A2 (en) * 1987-08-07 1989-02-08 Lion Technology Limited Fluid sampling systems
CN1676173A (zh) * 2004-03-31 2005-10-05 爱特玛医药股份公司 用于分析呼吸气体的设备
CN101379388A (zh) * 2006-02-03 2009-03-04 大塚制药株式会社 呼出气体测定分析方法及装置
CN101466436A (zh) * 2006-04-12 2009-06-24 普马特里克斯公司 测定颗粒产生的诊断装置
CN101742964A (zh) * 2007-06-27 2010-06-16 皇家飞利浦电子股份有限公司 用于分析呼吸系统的发炎状态的装置
CN102264404A (zh) * 2008-12-23 2011-11-30 美国政府卫生和公众服务部疾病预防和控制中心 肺部浮质收集装置
CN102498398A (zh) * 2009-09-09 2012-06-13 森撒部伊斯公司 呼出气中的药物检测
CN102596029A (zh) * 2009-10-22 2012-07-18 皇家飞利浦电子股份有限公司 用于测量呼出空气中气体的浓度的方法和设备
WO2012006250A1 (en) * 2010-07-06 2012-01-12 Deton Corp. System for airborne bacterial sample collection and analysis
WO2012120140A1 (en) * 2011-03-09 2012-09-13 Sensa Bues Ab A portable sampling device and method for sampling drug substances from exhaled breath

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US20160022946A1 (en) 2016-01-28
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WO2014165184A1 (en) 2014-10-09
US10080857B2 (en) 2018-09-25

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