CN1053373C - Ointment for treatment of psoriasis and preparation method thereof - Google Patents

Ointment for treatment of psoriasis and preparation method thereof Download PDF

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Publication number
CN1053373C
CN1053373C CN96115628A CN96115628A CN1053373C CN 1053373 C CN1053373 C CN 1053373C CN 96115628 A CN96115628 A CN 96115628A CN 96115628 A CN96115628 A CN 96115628A CN 1053373 C CN1053373 C CN 1053373C
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gram
raw material
doubly measures
kilograms
ointment
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CN1135353A (en
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韩珍
张维喜
陈秀娟
张建磊
张宜培
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张维喜
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Abstract

The present invention provides ointment for the treatment of psoriasis and a preparation method thereof. The ointment for the treatment of psoriasis is prepared by taking prism tuber, notoperygium root, pubescent angelica root, dahurian angelica, safflower, angelica, ledebouriella root, peach seed, ground beetle, centipede, scorpion, menthol, black-tail snake and azone as main raw materials and taking benne oil as a substrate to be mixed, heated, filtered and stirred. The ointment which can directly and indirectly cure psoriasis has the advantages of low cost, no toxic or side effect, high short-term curative effect, low long-term recurrence rate, simple preparation and little investment.

Description

Treat psoriatic ointment and method for making thereof
The present invention relates to a kind of Chinese medicine externally used paste and method for making thereof, more particularly relate to psoriatic Chinese medicine ointment of a kind of treatment and method for making thereof.
Existing medicine is divided into endo-medicine and external used medicine two parts to psoriatic treatment, but in therapeutic process usually based on external used medicine, comprise glucocorticoid ointment (0.015~0.09%) class, coal-tar ointment (5~20%) class, anthralin Ointment (0.05~1%) class or the like, be that substrate is formulated all, abroad based on anthraline class external used medicine with cream or vaseline.Said medicine is all effective in cure to psoriasis, but toxic and side effects is more, for example, occurs atrophoderma, skin irritation symptom after the medication that has, corticosteroid dermatitis, syndrome etc. behind the appearance hormone that has is cured back relapse rate height, particularly Chang Yong anthraline class and corticosteroids ointment in addition, more back state of an illness remission time is short, recurrence is fast, and consumption is big, the price height.
The purpose of this invention is to provide a kind of efficient, have no side effect, relapse rate and cost psoriatic ointment of treatment and method for making thereof low and easy to use.
The important step that onset of psoriasis lapses to is that meridians intercept, coagulation of QI-blood, and QI and blood two is strongly fragrant, the imbalance of body negative and positive of qi and blood.For realizing that purpose of the present invention takes promoting blood circulation to remove obstruction in the collateral, eliminating mass and relieving fullness is separated the stasis of blood, comfortable resolving depression, and it is pleasant to dissipate, the external therapy of Chinese herb scheme of dispelling wind for relieving itching.
One of purpose of the present invention can realize by following scheme: treat psoriatic ointment, its composition comprises:
I organizes raw material: a that rhizoma sparganic, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae are respectively (15~45 gram) doubly measures, and a that Flos Carthami, Radix Angelicae Sinensis, Radix Saposhnikoviae are respectively (20~50 gram) doubly measures, and a of Semen Persicae (5~30 gram) doubly measures;
II organizes raw material: a that ground beetle, Scolopendra, Scorpio, Mentholum are respectively (20~80 gram) doubly measures, and a of Zaocys (40~100 gram) doubly measures;
III organizes raw material: a of azone (5~20 gram) doubly measures.
The a of Oleum Sesami (1000~1500 gram) doubly measures,
Above a is any positive number, and following a all therewith together.
One of purpose of the present invention also can realize by following scheme:
Comprise also that in the II group raw material of forming a that Calculus Bovis, Squama Manis are respectively (20~80 gram) doubly measures, a of Indigo Naturalis (30~90 gram) doubly measures, and a of Realgar (20~50 gram) doubly measures.
Comprise also that in the I group raw material of forming a that Radix Aconiti Kusnezoffii, Radix Aconiti are respectively (15~45 gram) doubly measures, a of Radix Sophorae Flavescentis (20~50 gram) doubly measures.
Comprise also in addition that in the I group raw material of forming a that Rhizoma Smilacis Chinensis, Fructus Gleditsiae Abnormalis, Cortex Cinnamomi, Rhizoma Coptidis are respectively (15~45 gram) doubly measures.
The method for making of the psoriatic ointment of above-mentioned treatment is to comprise the steps:
(1) group of the I in will forming raw material adds in the container that Oleum Sesami is housed mix homogeneously and is heated to 100~200 ℃;
(2) filter and remove residue;
(3) the group raw material of the II in will forming (being processed into Powdered) joins in (2) and stirs into cream;
(4) group of the III in will forming raw material joins in (3) and stirs and tremble evenly, promptly makes the psoriatic ointment of treatment of the present invention.
Method for making of the present invention after heating stops, through 10~40 minutes natural coolings, is carried out filter and remove residue again, and then adding 10~15 gram Plumbum preparatium is preferred version.
The using method of ointment of the present invention:
A, ointment is beaten on parchamyn paper, about coin is thick, is cut into the skin lesion size, is affixed near place, acupuncture point affected part or the skin lesion then, and fixes with cloth or gauze, in case displacement was changed dressings once in 5~6 days.
B, ointment is applied near place, acupuncture point affected part or the skin lesion gently with cream cutter or bamboo let, about coin is thick, and package is fixed, and changes dressings once in 5~6 days.
C, be applied to affected part, every day three times gently with cotton rod or cloth etc.
The present invention has following advantage compared to existing technology:
1, this ointment can directly and indirectly be brought into play therapeutical effect to psoriasis, directly acts on the cellular metabolism that psoriatic lesion is regulated the affected part on the one hand, suppresses abnormal epidermal hyperplasia; On the other hand, can bring into play drug effect by the meridians internal organs, and the whole body meridian system is played regulating action, reach the purpose of effecting a permanent cure.Simultaneously, utilize the biological activity of external treatment Chinese medicine and through the cave itself outer quick property and enlarge-effect, with dose performance obvious treatment effect seldom.
2, add the skin penetrant azone, thereby increased skin to the absorption of medicine with strengthened drug effect.
3, the unguentum that forms for pure purification of tcm of the present invention, easy to use, price is low, has no side effect.
4, the anthracene skin frost of the present invention and prior art compares test for example, and its short term effect situation is as follows:
Group Total routine number Recovery from illness Produce effects Effectively Invalid Total effective rate
The present invention 248 83.06% 15.32% 12.1% 0.4% 99.6%
Anthracene skin frost 200 28% 48% 13% 11% 89%
Late result, relapse rate of the present invention are 50.97%, and anthracene skin frost relapse rate is 83.93%.
5, method for making of the present invention is simple, is easy to grasp, and small investment, is easy to get at wide raw material source, and production cost is low.
The present invention further specifies as follows in conjunction with the embodiments:
The psoriatic ointment of embodiment 1. treatments, its composition comprises: I organizes raw material: 1.5 kilograms of rhizoma sparganic, 4.5 kilograms of Rhizoma Et Radix Notopterygiis, 2.0 kilograms of Radix Angelicae Pubescentiss, 2.5 kilograms of the Radixs Angelicae Dahuricae, 2.5 kilograms on Flos Carthami, 5.0 kilograms of Radix Angelicae Sinensis, 3.0 kilograms of Radix Saposhnikoviaes, 1.0 kilograms in Semen Persicae; II organizes raw material: 2.0 kilograms of ground beetle, 2.0 kilograms of Scolopendras, 6.0 kilograms of Scorpio, 6.0 kilograms of Mentholums; 8.5 kilograms of Zaocyss; III organizes raw material: 1.0 kilograms of azones; 1100 kilograms in Oleum Sesami.
Embodiment 2.Treat psoriatic ointment, its composition comprises: I organizes raw material: 2.0 kilograms of rhizoma sparganic, 2.0 kilograms of Rhizoma Et Radix Notopterygiis, 3.0 kilograms of Radix Angelicae Pubescentiss, 4.0 kilograms of the Radixs Angelicae Dahuricae, 5.0 kilograms on Flos Carthami, 4.5 kilograms of Radix Angelicae Sinensis, 2.0 kilograms of Radix Saposhnikoviaes, 0.5 kilogram in Semen Persicae, 1.5 kilograms of Radix Aconiti Kusnezoffii, 4.5 kilograms of Radix Aconitis, 2.0 kilograms of Radix Sophorae Flavescentiss; II organizes raw material: 3.0 kilograms of ground beetle, and 7.0 kilograms of joy centipedes, 3.0 kilograms of Scorpio, 8.0 kilograms of Mentholums, 6.0 kilograms of Zaocyss, III organizes raw material: 0.5 kilogram of azone; 1200 kilograms in Oleum Sesami.
Embodiment 3.Treat psoriatic ointment, its composition comprises: I organizes raw material: 3.5 kilograms of rhizoma sparganic, 3.0 kilograms of Rhizoma Et Radix Notopterygiis, 1.5 kilograms of Radix Angelicae Pubescentiss, 4.5 kilograms of the Radixs Angelicae Dahuricae, 2.0 kilograms on Flos Carthami, 3.0 kilograms of Radix Angelicae Sinensis, 4.0 kilograms of Radix Saposhnikoviaes, 2.0 kilograms in Semen Persicae; II organizes raw material: 8.0 kilograms of ground beetle, 3.5 kilograms of Scolopendras, 8.0 kilograms of Scorpio, 2.0 kilograms of Mentholums, 4.0 kilograms of Zaocyss, 2.0 kilograms of Calculus Boviss, 8.0 kilograms of Squama Maniss, 9.0 kilograms of Indigo Naturaliss, 2.0 kilograms of Realgars; III organizes raw material: 1.5 kilograms of azones; 1300 kilograms in Oleum Sesami.
Embodiment 4.Treat psoriatic ointment, its composition comprises: I organizes raw material: 4.5 kilograms of rhizoma sparganic, 1.5 kilograms of Rhizoma Et Radix Notopterygiis, 4.5 kilograms of Radix Angelicae Pubescentiss, 1.5 kilograms of the Radixs Angelicae Dahuricae, 3.0 kilograms on Flos Carthami, 2.0 kilograms of Radix Angelicae Sinensis, 5.0 kilograms of Radix Saposhnikoviaes, 3.0 kilograms in Semen Persicae, 4.5 kilograms of Radix Aconiti Kusnezoffii, 1.5 kilograms of Radix Aconitis, 5.0 kilograms of Radix Sophorae Flavescentiss, 1.5 kilograms of Rhizoma Smilacis Chinensiss, 4.5 kilograms of Fructus Gleditsiae Abnormalis, 2.0 kilograms of Cortex Cinnamomis, 2.5 kilograms of Rhizoma Coptidis, 6.0 kilograms of ground beetle, 8.0 kilograms of Scolopendras, 2.0 kilograms of Scorpio, 4.0 kilograms of Mentholums, 10.0 kilograms of Zaocyss, 8.0 kilograms of Calculus Boviss, 2.0 kilograms of Squama Maniss, 3.0 kilograms of Indigo Naturaliss, 5.0 kilograms of Realgars; III organizes raw material: 2.0 kilograms of azones; 1500 kilograms in Oleum Sesami.
One of method for making of the psoriatic ointment of above-mentioned treatment is: I in will forming group raw material adds one and mix homogeneously is housed in the container of Oleum Sesami and is heated to 120 ℃, the cooled and filtered slagging-off, again II group raw material (being processed into Powdered) is joined in the Oleum Sesami of slagging-off after filtration, stir into cream, add III group raw material at last and stir, promptly make the psoriatic ointment of treatment of the present invention.
Two of the method for making of the psoriatic ointment of above-mentioned treatment is: I in will forming group raw material joins in the container that Oleum Sesami is housed mix homogeneously and is heated to 140 ℃, through natural cooling after-filtration slagging-off in 30 minutes, add 12 gram Plumbum preparatium then, again II group raw material (being processed into Powdered) is joined in the aforesaid Oleum Sesami, stir into cream, add III group raw material at last and stir, promptly make the psoriatic ointment of treatment of the present invention.
The present invention is not restricted to the described embodiments, the technical staff can be in the scope of known technology flexible.

Claims (6)

1, treat psoriatic ointment, it is characterized in that its composition comprises:
A, I organize raw material: rhizoma sparganic, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, and a that is respectively (15~45 gram) doubly measures, and a that Flos Carthami, Radix Angelicae Sinensis, Radix Saposhnikoviae are respectively (20~50 gram) doubly measures, and a of Semen Persicae (5~30 gram) doubly measures.
B, II organize raw material: a that ground beetle, Scolopendra, Scorpio, Mentholum are respectively (20~80 gram) doubly measures, and a of Zaocys (40~100 gram) doubly measures;
C, III organize raw material: a of azone (5~20 gram) doubly measures;
The a of D, Oleum Sesami (1000~1500 gram) doubly measures;
Above a is any positive number, and following a all therewith together.
2, the psoriatic ointment of treatment according to claim 1 is characterized in that also comprising that a that Calculus Bovis, Squama Manis are respectively (20~80 gram) doubly measures in the II group raw material of forming, a of Indigo Naturalis (30~90 gram) doubly measures, and a of Realgar (20~50 gram) doubly measures
3, the psoriatic ointment of treatment according to claim 1 is characterized in that also comprising that a that Radix Aconiti Kusnezoffii, Radix Aconiti are respectively (15~45 gram) doubly measures in the I group raw material of forming, a of Radix Sophorae Flavescentis (20~50 gram) doubly measures.
4, the psoriatic ointment of treatment according to claim 3 is characterized in that also comprising that a that Rhizoma Smilacis Chinensis, Fructus Gleditsiae Abnormalis, Cortex Cinnamomi, Rhizoma Coptidis are respectively (15~45 gram) doubly measures in the I group raw material of forming.
5, the method for making of the psoriatic ointment of above-mentioned treatment is characterized in that comprising the steps:
A, the group of the I in will forming raw material add in the container that Oleum Sesami is housed mix homogeneously and are heated to 100~200 ℃;
B, filter and remove residue;
C, the group of the II in will forming raw material are processed among the Powdered B of joining and stir into cream;
D, the group of the III in will forming raw material join among the C and stir, and promptly make the psoriatic ointment of treatment of the present invention.
6, the method for making of the psoriatic ointment of treatment according to claim 5, it is characterized in that heating stops after, through 10~40 minutes natural coolings, carry out filter and remove residue again, then add Plumbum preparatium 10~15 gram.
CN96115628A 1996-01-24 1996-01-24 Ointment for treatment of psoriasis and preparation method thereof Expired - Fee Related CN1053373C (en)

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Application Number Priority Date Filing Date Title
CN96115628A CN1053373C (en) 1996-01-24 1996-01-24 Ointment for treatment of psoriasis and preparation method thereof

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CN1053373C true CN1053373C (en) 2000-06-14

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI438000B (en) * 2011-02-18 2014-05-21 Galderma Res & Dev Oil-extracted products of indigo naturalis, and the preparation process and uses thereof
CN102225143B (en) * 2011-06-05 2012-08-22 展继军 Medicine for external use for treating psoriasis
CN103520587A (en) * 2012-08-31 2014-01-22 张国辉 Snake oil ringworm ointment and preparation method
CN103007050B (en) * 2013-01-14 2014-10-22 马加明 External Chinese medicament for drawing out poison
CN103961498A (en) * 2013-01-31 2014-08-06 贾秀文 Drug for treating psoriasis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
中药药学报1984(4) 1984.1.1 孙淑英等,洗剂在外科临床的应用 *

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