CN105310793B - A kind of mouse brain dissects special brain body fixer - Google Patents

A kind of mouse brain dissects special brain body fixer Download PDF

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Publication number
CN105310793B
CN105310793B CN201510771345.1A CN201510771345A CN105310793B CN 105310793 B CN105310793 B CN 105310793B CN 201510771345 A CN201510771345 A CN 201510771345A CN 105310793 B CN105310793 B CN 105310793B
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CN
China
Prior art keywords
tweezer
arm
tweezer arm
brain
dissects
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CN201510771345.1A
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Chinese (zh)
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CN105310793A (en
Inventor
赵翔翔
赵忠新
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Priority to CN201510771345.1A priority Critical patent/CN105310793B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/003Appliances for supporting or fettering animals for operative purposes with head or neck restraining means

Abstract

Special brain body fixer is dissected the present invention relates to a kind of mouse brain, including two tweezer arms, the root of first tweezer arm and the second tweezer arm is connected in tweezer handle, the first tweezer arm, the second tweezer arm can be clamped inwardly, also include the 3rd tweezer arm, there is pivot in the tweezer handle, the axis of pivot is parallel with the direction of motion of the first tweezer arm, the second tweezer arm, and the 3rd described tweezer arm is articulated with pivot.The beneficial effects of the invention are as follows utilize the precise match for only improving the adjustable special-shaped tweezer of type more, so as to keep being brought into close contact in brain fixation procedure, avoid the poorly efficient fixation of conventional fixation means, and sharp instrument in fixation procedure to the possible infringement of brain parenchym, therefore when carrying out fine dissection to brain or obtaining fixed brain area brain body, remainder brain body can be fully fixed, and then obtains complete purpose brain area.

Description

A kind of mouse brain dissects special brain body fixer
Technical field
The present invention relates to experiment appliance, and in particular to mouse brain dissects special brain body fixer.
Background technology
In various biological tests, mouse is using a kind of most experimental animals.Carrying out mouse brain fine dissection at present When, the most frequently used setting tool is various straight, elbow tweezers.And mouse brain its matter when fresh is soft frangible, and brain body is because of ischemic Time slightly length just causes brain body to dissolve due to the autophagocytosis of cell, is more difficult to carry out accurate operation.Due to tweezers have compared with The tweezer head of point, and the more difficult control of strength of finger, are easily destroyed mouse brain, cause final operation success rate to reduce, and influence purpose The acquisition of brain area.
The content of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of fixation for the muroid brain for being easy to operate Instrument.
Special brain body fixer, including two tweezer arms, first are dissected there is provided a kind of mouse brain to achieve the above object of the invention The root of tweezer arm and the second tweezer arm is connected in tweezer handle, and the first tweezer arm, the second tweezer arm can be clamped inwardly, in addition to the 3rd tweezer There are pivot, the axis of pivot threeth tweezer parallel, described with the direction of motion of the first tweezer arm, the second tweezer arm in arm, the tweezer handle Arm is articulated with pivot.
The fixation that first tweezer arm and the second tweezer arm are used in a plane, and the 3rd tweezer arm is used to aid in fixing, due to The pivot of 3rd tweezer arm rotation is parallel with the first tweezer arm, the second tweezer arm direction of motion when axial, therefore the fortune of the 3rd tweezer arm The dynamic plane that is formed is to be sitting in that plane is perpendicular in itself with the first tweezer arm, the second tweezer arm, and the layout of this form is conducive to the 3rd The angle control of tweezer arm, is more beneficial for the clamping of muroid cerebellum.
It is preferred that, in addition to have accommodating rack-and-pinion for adjusting in the first knob of the 3rd tweezer arm anglec of rotation, tweezer handle First cavity of mechanism, the first gear is fixedly connected on the first rotation axis, the root of first rack and the 3rd tweezer arm Portion is connected.
First cavity is included on the slideway for accommodating rack and the gear cavity for accommodating gear, the afterbody of the first rotation axis coaxially Fixed gear, makes gear rotate and rotate by knob in gear cavity, and wheel and rack, which is engaged, causes rack energy in slideway Enough vertical movements, pass through the connection of rack and the 3rd tweezer arm afterbody so that with pivotally connected the 3rd tweezer arm one lever of formation Mechanism, is rotated by turn knob band moving gear, so as to carry-over bar motion, finally cause the 3rd tweezer arm around pivoting control The movement angle of 3rd tweezer arm.
It is preferred that, in addition to the first tweezer arm of regulation, the second knob of the second inwall gripping angle, there is accommodating gear in tweezer handle Second cavity of rackwork, described second gear is fixedly connected on the second rotation axis, on the first tweezer arm and the second tweezer arm Connecting rod is respectively articulated with, two connecting rods are hinged with the second rack end.
The drive connection of second knob is similar with the first knob, and first half still uses pinion and rack, and later half Partial transmission, by the first tweezer arm and the second tweezer arm articulated linkage be articulated with rack form linkage again, rack Movement, drive two connecting rods to open entire or gripping angle between the first tweezer arm and the second tweezer arm to outer support so as to adjusting.
It is preferred that, there is a tweezer head at the tip of each tweezer arm, and tweezer head and tweezer arm are in knuckle, the 3rd tweezer arm and the 3rd tweezer capitiform into Plane perpendicular to the first tweezer arm and the second tweezer arm formation plane.
Tweezer head is conducive to preferably clamping mouse brain, protects mouse brain not to be caught broken, and the tweezer head especially with certain angle can To change stress, preferably mouse brain is protected.
It is preferred that, there is arc groove on the inside of described tweezer head.
It is preferred that, described anti-skid structure is the screw thread for being distributed in groove inner surface.
The mouse brain of the present invention dissects special brain body fixer, and traditional tweezers shape is transformed, three are employed Tweezer arm grips the mode of mouse brain, sets the 3rd tweezer arm to carry out auxiliary to mouse brain and fixes, and there is provided knob controls the 3rd tweezer The angle of arm, is conducive to muroid brain to fix.
The beneficial effects of the invention are as follows using the precise match for only improving the adjustable special-shaped tweezer of type more, so that solid to brain During fixed it can keep being brought into close contact, it is to avoid the poorly efficient fixation of conventional fixation means, and sharp instrument is in fixation procedure To the possible infringement of brain parenchym, therefore when carrying out fine dissection to brain or obtaining fixed brain area brain body, can fully it fix Remainder brain body, and then obtain complete purpose brain area.
Brief description of the drawings
Fig. 1 is the schematic diagram that mouse brain of the present invention dissects special brain body fixer;
Fig. 2 is the sectional view that mouse brain of the present invention dissects special brain body fixer;
Fig. 3 is the front view that mouse brain of the present invention dissects special brain body fixer;
Wherein:
1- tweezer arm 11- the first tweezer arm 12- the second tweezer arms
The tweezer arm 2- tweezer handle 21- pivots of 13- the 3rd
22- slideway 23- gear cavity 24- axocoels
31- the first knob 32- the second knob the first racks of 41-
42- the second rack 51- first gears the second racks of 52-
61- first connecting rod 62- second connecting rod 7- arc grooves
8- tweezer head 81- the first tweezer head 82- the second tweezer heads
The tweezer heads of 83- the 3rd
Embodiment
Below in conjunction with the drawings and specific embodiments, the present invention will be further described.
A kind of mouse brain according to Fig. 1, Fig. 2, Fig. 3 dissects special brain body fixer, including tweezer arm 1, tweezer handle 2 and tweezer First 8.The root of first tweezer arm 11 and the second tweezer arm 12 is connected in tweezer handle 2, the first tweezer arm 11 and the second tweezer arm 12 can clamp or Open entire, the 3rd tweezer arm 13 is articulated with the pivot 21 of tweezer handle 2, the axis of pivot 21 and the first tweezer arm 11, the fortune of the second tweezer arm 12 Dynamic direction is parallel so that the plane of the first tweezer arm 11 and the second tweezer arm 12 composition moves the plane phase formed with the 3rd tweezer arm 13 It is mutually vertical.In the case, three tweezer arms formation, two kinematic pairs, one is the clamping of the first tweezer arm 11 and the second tweezer arm 12 and Entire motion is opened, the second is the motion that the 3rd tweezer arm 13 rotates around pivot 21.There are the first knob 31 and the second knob in tweezer handle 2 32, the first knob 31 is used to adjust angle of the 3rd tweezer arm 13 around pivot 21, and the second knob 32 is used to adjust the He of the first tweezer arm 11 Angle between second tweezer arm 12.Having between described tweezer handle 2 has a slideway 22, slideway in two cavitys, each cavity 22 are connected with a gear cavity 23, there is axocoel 24 between gear cavity 23 and tweezer handle outer wall.By taking the transmission of the first knob 31 as an example, It is used to set the first rack 41 in slideway 22, the first described rack 41 can be put in slideway 22 in up and down slideway, gear cavity 23 First gear 51 is put, described first gear 51 is engaged with rack 41, first gear 51 and the rotation axis of the first knob 31 are fixed Connection, both coaxially fix, and rotation axis connects the first knob 31 after passing through axocoel 24, when rotating the first knob 31, drive the One gear 51 rotates, so that the first rack 41 of engagement is slided.Second knob 32 equally connection second gear 52 simultaneously drives the The rack 41 of two rack 42. first connects the 3rd tweezer arm 13, because the 3rd tweezer arm 13 is articulated with pivot 21, forms leverage, the One rack 41 can drive the 3rd tweezer arm 13 around pivoting when moving.And the second rack 42 then connects linkage, linkage Including the first connecting rod 61 being articulated with the first tweezer arm 11 and the second connecting rod 62 being articulated with the second tweezer arm 12, first connecting rod 61 The end of the second rack 42 is articulated with the other end of second connecting rod 62.When the second rack 42 is pushed down on, the first tweezer arm 11 Strutted with the second tweezer arm 12 to both sides, so as to have adjusted the angle between two tweezer arms 1.
There is tweezer first 8 on each tweezer arm 1, be knuckle between tweezer first 8 and tweezer arm 1, wherein the 3rd tweezer first 83 and the 3rd tweezer The plane formed between the plane and the first tweezer arm 11 and the second tweezer arm 12 of the formation of arm 13 is mutually perpendicular to.First 8 inner surface of tweezer has one Individual arc groove 7, meets the curvature on mouse brain surface, has screw thread in the inner surface of arc groove 7.
The preferred embodiment to the invention is illustrated above, but the invention be not limited to it is described Embodiment, those skilled in the art can also make a variety of etc. on the premise of without prejudice to the invention spirit Same modification or replacement, these equivalent modifications or replacement are all contained in the application claim limited range.

Claims (5)

1. a kind of mouse brain dissects special brain body fixer, including two tweezer arms, the root connection of the first tweezer arm and the second tweezer arm In in tweezer handle, the first tweezer arm, the second tweezer arm can be clamped inwardly, it is characterised in that also be included:
There is pivot in 3rd tweezer arm, the tweezer handle, the axis of pivot is parallel with the direction of motion of the first tweezer arm, the second tweezer arm, institute The 3rd tweezer arm stated is articulated with pivot, is additionally included in the first knob for adjusting the 3rd tweezer arm anglec of rotation, tweezer handle There is the first cavity of accommodating pinion and rack, first gear is fixedly connected on the first rotation axis, the first rack and the 3rd tweezer The root of arm is connected;
There is tweezer head at the tip of each tweezer arm, and the tweezer head is in knuckle with tweezer arm.
2. mouse brain according to claim 1 dissects special brain body fixer, it is characterised in that also including adjusting the first tweezer There is the second cavity of accommodating pinion and rack in second knob of arm, the second tweezer arm gripping angle, tweezer handle, second gear is fixed It is connected on the second rotation axis, connecting rod is respectively articulated with the first tweezer arm and the second tweezer arm, two connecting rods and the second rack end is cut with scissors Connect.
3. mouse brain according to claim 2 dissects special brain body fixer, it is characterised in that the 3rd tweezer arm and the 3rd tweezer Capitiform into plane perpendicular to the first tweezer arm and the second tweezer arm formation plane.
4. mouse brain according to claim 3 dissects special brain body fixer, it is characterised in that have on the inside of described tweezer head Arc groove.
5. mouse brain according to claim 4 dissects special brain body fixer, it is characterised in that anti-skid structure is recessed to be distributed in The screw thread of groove inner surface.
CN201510771345.1A 2015-11-12 2015-11-12 A kind of mouse brain dissects special brain body fixer Active CN105310793B (en)

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Application Number Priority Date Filing Date Title
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CN105310793B true CN105310793B (en) 2017-08-25

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Publication number Priority date Publication date Assignee Title
CN106725970B (en) * 2016-12-30 2018-08-21 四川格林泰科生物科技有限公司 A kind of special equipment for opening monkey brain

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201183226Y (en) * 2008-04-16 2009-01-21 汤继云 Steady holding type hand forceps
KR20110008431U (en) * 2010-02-23 2011-08-31 박범수 9688 Forcep No 9688 For Veterinary Surgury
CN202096277U (en) * 2011-06-07 2012-01-04 费红霞 Novel medical easily controlled obstetrical forceps
CN202478247U (en) * 2012-03-23 2012-10-10 张秀华 Craniocerebral operation drainage fixation clamp
CN203059835U (en) * 2013-01-23 2013-07-17 尚同祥 Tumor holder
CN203763287U (en) * 2014-04-10 2014-08-13 青岛农业大学 Experimental animal tissue forceps
CN204411016U (en) * 2015-01-08 2015-06-24 车光昇 Toy heart not damaged fixation forceps
CN204671230U (en) * 2015-05-09 2015-09-30 苏州爱友电器有限公司 A kind of medical tweezers
CN205286589U (en) * 2015-11-12 2016-06-08 中国人民解放军第二军医大学 Appearance is fixed to mouse brain

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