CN105310793A

CN105310793A - Brain body fixing instrument specially used for rat brain dissection

Info

Publication number: CN105310793A
Application number: CN201510771345.1A
Authority: CN
Inventors: 赵翔翔; 赵忠新
Original assignee: Second Military Medical University SMMU
Current assignee: Second Military Medical University SMMU
Priority date: 2015-11-12
Filing date: 2015-11-12
Publication date: 2016-02-10
Anticipated expiration: 2035-11-12
Also published as: CN105310793B

Abstract

The invention relates to a brain body fixing instrument specially used for rat brain dissection. The brain body fixing instrument comprises two tweezer arms, wherein the roots of the first tweezer arm and the second tweezer arm are connected to a tweezer handle, and the first tweezer arm and the second tweezer arm can tightly clamp inwards; the brain body fixing instrument further comprises a third tweezer arm, wherein a pivoting shaft is arranged on the tweezer handle, the axis of the pivoting shaft is parallel to the movement direction of the first tweezer arm and the second tweezer arm, and the third tweezer arm is hinged to the pivoting shaft. The brain body fixing instrument has the beneficial effects that by utilizing the accurate matching of a plurality of improved adjustable specially-shaped tweezers, the close attaching is kept during the fixing process of the brain, so that the low-efficiency fixing of the traditional fixing device is avoided, the possible injury caused to the brain parenchyma by sharp instruments in the fixing process is avoided, and therefore, in the fine dissection for the brain or in the process of obtaining the brain body in the area of the fixed brain, the other parts of the brain body can be sufficiently fixed, and the complete destination brain area is obtained.

Description

A kind of Mus brain dissects special brain body fixer

Technical field

The present invention relates to experiment appliance, be specifically related to Mus brain and dissect special brain body fixer.

Background technology

In various biological test, Mus adopts maximum a kind of laboratory animals.At present when carrying out Mus brain fine dissection, the most frequently used setting tool is various straight, elbow tweezers.And Mus brain its matter and soft frangible when fresh, and brain body just causes brain body to dissolve because Ischemia Time is slightly long due to the autophagocytosis of cell, general is more difficult carry out accurate operation.Because tweezers have sharper tweezer head, and the more difficult control of strength of finger, easily destroy Mus brain, cause final successful operation rate to reduce, affect the acquisition in object brain district.

Summary of the invention

The object of the invention is to overcome the deficiencies in the prior art, a kind of fixer of muroid brain of convenient operation is provided.

To achieve the above object of the invention, a kind of Mus brain is provided to dissect special brain body fixer, comprise two tweezer arms, the root of the first tweezer arm and the second tweezer arm is connected on tweezer handle, described first tweezer arm, the second tweezer arm can inwardly clamp, and also comprise the 3rd tweezer arm, and described tweezer handle has pivot, the axis of pivot is parallel with the direction of motion of the first tweezer arm, the second tweezer arm, and the 3rd described tweezer arm is articulated with on pivot.

First tweezer arm and the second tweezer arm are used for fixing in a plane, and the 3rd tweezer arm is used for auxiliary fixing, due to the 3rd tweezer arm rotate pivot shaft to time parallel with the first tweezer arm, the second tweezer arm direction of motion, therefore the plane that the motion of the 3rd tweezer arm is formed itself is sitting in plane being perpendicular with the first tweezer arm, the second tweezer arm, the layout of this form is conducive to the Angle ambiguity of the 3rd tweezer arm, is more conducive to the clamping of muroid cerebellum.

Preferably, also comprise the first knob for regulating the 3rd tweezer arm anglec of rotation, have the first cavity of accommodating pinion and rack in tweezer handle, described first gear is fixedly connected on the first rotation axis, and described first tooth bar is connected with the root of the 3rd tweezer arm.

First cavity comprises the slideway holding tooth bar and the gear cavity holding gear, fixed gear coaxially on the afterbody of the first rotation axis, gear is made to be rotated by knob in gear cavity and rotate, wheel and rack engagement makes tooth bar can move both vertically in slideway, by the connection of tooth bar and the 3rd tweezer arm afterbody, make to form a leverage with the 3rd pivotally connected tweezer arm, rotated by rotary knob driven gear, thus the motion of band carry-over bar, finally make the movement angle of the 3rd tweezer arm pivotally Spin Control the 3rd tweezer arm.

Preferably, also comprise the second knob of adjustment first tweezer arm, the second inwall gripping angle, the second cavity of accommodating pinion and rack is had in tweezer handle, the second described gear is fixedly connected on the second rotation axis, articulated linkage respectively on first tweezer arm and the second tweezer arm, two connecting rods and the second tooth bar end hinged.

Drive connection and first knob of the second knob are similar, first half still adopts pinion and rack, and the transmission of latter half, be articulated with again on tooth bar by articulated linkage on the first tweezer arm and the second tweezer arm and form linkage, the movement of tooth bar, drives two connecting rods to outer support thus regulates and open entire or gripping angle between the first tweezer arm and the second tweezer arm.

Preferably, all there is tweezer head at the tip of each tweezer arm, and tweezer head and tweezer arm are knuckle, the plane that the plane orthogonal that the 3rd tweezer arm becomes with the 3rd tweezer capitiform is formed in the first tweezer arm and the second tweezer arm.

Tweezer head is conducive to better clamping Mus brain, and protection Mus brain is not caught broken, and especially has the tweezer head of certain angle, can change stressed, better protect Mus brain.

Preferably, arc groove is had inside described tweezer head.

Preferably, described anti-skid structure is the screw thread being distributed in groove inner surface.

Mus brain of the present invention dissects special brain body fixer, traditional tweezers shape is transformed, have employed the mode of three tweezer arm gripping Mus brains, the 3rd tweezer arm is set and has carried out assisting fixing to Mus brain, and be provided with the angle that knob controls the 3rd tweezer arm, be conducive to muroid brain and fix.

The invention has the beneficial effects as follows the precise match utilizing many modified model scalable abnormity tweezers, thus can keep fitting tightly in brain fixation procedure, the poor efficiency avoiding conventional fixation means is fixed, and the infringement that sharp instrument is possible to brain essence in fixation procedure, therefore when carrying out fine dissection to brain or obtaining fixing brain district brain body, fully can fix remainder brain body, and then obtain complete object brain district.

Accompanying drawing explanation

Fig. 1 is the schematic diagram that Mus brain of the present invention dissects special brain body fixer;

Fig. 2 is the sectional view that Mus brain of the present invention dissects special brain body fixer;

Fig. 3 is the front view that Mus brain of the present invention dissects special brain body fixer;

Wherein:

1-tweezer arm 11-first tweezer arm 12-second tweezer arm

13-the 3rd tweezer arm 2-tweezer handle 21-pivot

22-slideway 23-gear cavity 24-axocoel

31-first knob 32-second knob 41-first tooth bar

42-second tooth bar 51-first gear 52-second tooth bar

61-first connecting rod 62-second connecting rod 7-arc groove

8-tweezer head 81-first tweezer head 82-second tweezer head

83-the 3rd tweezer head

Detailed description of the invention

Below in conjunction with the drawings and specific embodiments, the present invention will be further described.

A kind of Mus brain according to Fig. 1, Fig. 2, Fig. 3 dissects special brain body fixer, comprises tweezer arm 1, tweezer handle 2 and tweezer head 8.The root of the first tweezer arm 11 and the second tweezer arm 12 is connected on tweezer handle 2, first tweezer arm 11 and the second tweezer arm 12 can clamp or open entire, 3rd tweezer arm 13 is articulated with on the pivot 21 of tweezer handle 2, the axis of pivot 21 parallels with the direction of motion of the first tweezer arm 11, second tweezer arm 12, and the plane that the first tweezer arm 11 and the second tweezer arm 12 are formed and the 3rd tweezer arm 13 plane formed of moving is mutually vertical.In the case, three tweezer arms form two kinematic pairs, the clamping of the first first tweezer arm 11 and the second tweezer arm 12 and open entire motion, and it two is pivotally 21 motions rotated of the 3rd tweezer arm 13.Tweezer handle 2 has the first knob 31 and the second knob 32, first knob 31 for adjust the 3rd tweezer arm 13 pivotally 21 angle, the second knob 32 is for regulating the angle between the first tweezer arm 11 and the second tweezer arm 12.Have two cavitys between described tweezer handle 2, all have a slideway 22 in each cavity, slideway 22 is connected with a gear cavity 23, has axocoel 24 between gear cavity 23 and tweezer handle outer wall.For the transmission of the first knob 31, for arranging the first tooth bar 41 in slideway 22, the first described tooth bar 41 can in slideway 22 up and down slideway, place the first gear 51 in gear cavity 23, the first described gear 51 engages with tooth bar 41, first gear 51 is fixedly connected with the rotation axis of the first knob 31, both are coaxial fixing, and rotation axis connects the first knob 31 through after axocoel 24, when rotation the first knob 31, drive the first gear 51 to rotate, thus the first tooth bar 41 of engagement is slided.Second knob 32 connects the second gear 52 equally and drives the second tooth bar 42. first tooth bar 41 to connect the 3rd tweezer arm 13, because the 3rd tweezer arm 13 is articulated with pivot 21, forms leverage, the 3rd tweezer arm 13 can be driven when the first tooth bar 41 moves pivotally to rotate.Second tooth bar 42 then connection linkage, linkage comprises the first connecting rod 61 be articulated with on the first tweezer arm 11 and the second connecting rod 62 be articulated with on the second tweezer arm 12, and the other end of first connecting rod 61 and second connecting rod 62 is articulated with the end of the second tooth bar 42.When the second tooth bar 42 promotes downwards, the first tweezer arm 11 and the second tweezer arm 12 strut to both sides, thus have adjusted the angle between two tweezer arms 1.

Each tweezer arm 1 all has tweezer head 8, is knuckle between tweezer head 8 and tweezer arm 1, and wherein the plane that formed of the 3rd tweezer head 83 and the 3rd tweezer arm 13 is mutually vertical with the plane formed between the first tweezer arm 11 and the second tweezer arm 12.Tweezer head 8 inner surface has an arc groove 7, meets the curvature on Mus brain surface, has screw thread at arc groove 7 inner surface.

Below the preferred embodiment of the invention is illustrated, but the invention is not limited to described embodiment, those of ordinary skill in the art can also make all equivalent modification or replacement under the prerequisite without prejudice to the invention spirit, and these equivalent modifications or replacement are all included in the application's claim limited range.

Claims

1. a Mus brain dissects special brain body fixer, comprise two tweezer arms, the root of the first tweezer arm and the second tweezer arm is connected on tweezer handle, described first tweezer arm, the second tweezer arm can inwardly clamp, it is characterized in that, also comprise the 3rd tweezer arm, described tweezer handle has pivot, the axis of pivot is parallel with the direction of motion of the first tweezer arm, the second tweezer arm, and the 3rd described tweezer arm is articulated with on pivot.

2. Mus brain according to claim 1 dissects special brain body fixer, it is characterized in that, also comprise the first knob for regulating the 3rd tweezer arm anglec of rotation, the first cavity of accommodating pinion and rack is had in tweezer handle, described first gear is fixedly connected on the first rotation axis, and described first tooth bar is connected with the root of the 3rd tweezer arm.

3. Mus brain according to claim 2 dissects special brain body fixer, it is characterized in that, also comprise the second knob of adjustment first tweezer arm, the second inwall gripping angle, the second cavity of accommodating pinion and rack is had in tweezer handle, the second described gear is fixedly connected on the second rotation axis, articulated linkage respectively on first tweezer arm and the second tweezer arm, two connecting rods and the second tooth bar end hinged.

4. Mus brain according to claim 3 dissects special brain body fixer, it is characterized in that, all there is tweezer head at the tip of each tweezer arm, and tweezer head and tweezer arm are knuckle, the plane that the plane orthogonal that the 3rd tweezer arm becomes with the 3rd tweezer capitiform is formed in the first tweezer arm and the second tweezer arm.

5. dissect special brain body fixer according to claim 4 to described Mus brain, it is characterized in that, inside described tweezer head, have arc groove.

6. Mus brain according to claim 5 dissects special brain body fixer, it is characterized in that, described anti-skid structure is the screw thread being distributed in groove inner surface.