CN105288380A - Preparation method of traditional Chinese medicine composition for treating tinea diseases of cats and dogs - Google Patents
Preparation method of traditional Chinese medicine composition for treating tinea diseases of cats and dogs Download PDFInfo
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- CN105288380A CN105288380A CN201410306423.6A CN201410306423A CN105288380A CN 105288380 A CN105288380 A CN 105288380A CN 201410306423 A CN201410306423 A CN 201410306423A CN 105288380 A CN105288380 A CN 105288380A
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Abstract
The invention provides a preparation method of a traditional Chinese medicine composition for treating tinea diseases of cats and dogs. The traditional Chinese medicine composition comprises raw radix stemonae, cortex phellodendri, natural borneol, camphor and 70-75% (v/v) ethanol, wherein every 79-81ml of 70-75% (v/v) ethanol contains 6-9g of raw radix stemonae, 6-9g of cortex phellodendri, 1-3g of natural borneol and 1-3g of camphor. The traditional Chinese medicine composition prepared through an impregnation method has the advantages that traditional Chinese medicine materials are reasonably combined to achieve synergic effects of inhibiting bacteria and resisting inflammation and clearing away heat and toxic materials, and the traditional Chinese medicine composition is effective in the prevention and treatment of the tinea diseases of cats and dogs, simple and convenient to use and low in use amount. The preparation method of the traditional Chinese medicine composition is simple and capable of satisfying the requirements of large-scale industrial production.
Description
Technical field
The present invention relates to a kind of preparation method of Chinese medicine composition, especially a kind ofly prevent and treat Chinese medicine composition of cat dog tinea and preparation method thereof.
Background technology
Tinea is a kind of dermatosis of fungal infection in simple terms, is mainly in the places such as the face of cat dog, trunk, extremity and afterbody, occurs circular or oval tinea speckle, is covered with the squama of Lycoperdon polymorphum Vitt above, with the phosphor dot of the visible purple of ultraviolet lamps irradiates.The hair color of ill cat dog can become coarse, and the fur pugil pugil of tinea speckle part comes off and fractures or come off, and infected cat dog can feel very itch incomparable and go repeatedly to scratch, so disease sites can form alopecia areata.Tinea also can be transmitted to the mankind, causes application on human skin pruritus, decortication.Tinea is more common in malnutrition and weak and sickly cat and dog, and the absorption of the particularly vitamin B group of having additional nutrients, is conducive to the recovery preventing this disease and caught an illness animal.The fungus infecting cat dog has 2 kinds, i.e. Sabouraudites lanosus and Trichophyton mentagrophytes, and 98% is Sabouraudites lanosus, along with the differentiation of disease, becomes the circular macule of drying excitatory (tinea circinata).Present stage is mainly the antifungal drug such as griseofulvin, clotrimazole for the treatment of cat dog tinea, less for utilizing of Chinese medicine, and utilize the Chinese herbal medicine resource of China's abundant to develop the Chinese medicine preparation of applicable control cat dog tinea, there is provided new thinking by the clinical treatment for cat dog tinea, also there is boundless market prospect simultaneously.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine composition preventing and treating cat dog tinea.
Another technical problem to be solved by this invention is the preparation method of the Chinese medicine composition providing above-mentioned control cat dog tinea.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine composition preventing and treating cat dog tinea, be made up of Radix Stemonae, Cortex Phellodendri, natural Broneolum Syntheticum, Camphora and 70-75% (v/v) ethanol, wherein, Radix Stemonae 6-9g, Cortex Phellodendri 6-9g, natural Broneolum Syntheticum 1-3g, Camphora 1-3g is contained in every 79-81ml70-75% (v/v) ethanol.
Preferably, the Chinese medicine composition of above-mentioned control cat dog tinea, is obtained by following method:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, according to the consumption flooding Radix Stemonae 6-9g, Cortex Phellodendri 6-9g in every 79-81ml70-75% (v/v) ethanol, add 70-75% (v/v) ethanol of percent by volume 50-60% for the first time, Mi Gai, flood seven, collect impregnation liquid; In remaining slag charge, add remaining 70-75% (v/v) ethanol, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, according to add in every 79-81ml70-75% (v/v) ethanol natural Broneolum Syntheticum 1-3g, Camphora 1-3g add natural Broneolum Syntheticum, Camphora with magnitude relation, mixing, to obtain final product.
Preferably, the Chinese medicine composition of above-mentioned control cat dog tinea, containing Radix Stemonae 7-8g, Cortex Phellodendri 7-8g, natural Broneolum Syntheticum 2-3g, Camphora 1-2g in every 79-80ml70-75% (v/v) ethanol.
Preferably, the Chinese medicine composition of above-mentioned control cat dog tinea, containing Radix Stemonae 8g, Cortex Phellodendri 7g, natural Broneolum Syntheticum 3g, Camphora 2g in every 80ml70-75% (v/v) ethanol.
The preparation method of the Chinese medicine composition of above-mentioned control cat dog tinea, concrete preparation process is as follows:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, according to the consumption flooding Radix Stemonae 6-9g, Cortex Phellodendri 6-9g in every 79-81ml70-75% (v/v) ethanol, add 70-75% (v/v) ethanol of percent by volume 50-60% for the first time, Mi Gai, flood seven, collect impregnation liquid; In remaining slag charge, add remaining 70-75% (v/v) ethanol, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, according to add in every 79-81ml70-75% (v/v) ethanol natural Broneolum Syntheticum 1-3g, Camphora 1-3g add natural Broneolum Syntheticum, Camphora with magnitude relation, mixing, to obtain final product.
The invention has the beneficial effects as follows:
The Chinese medicine composition of above-mentioned control cat dog tinea, by Chinese medicine reasonable formula, mutual Synergistic, have antibacterial anti-inflammatory, malicious effect is fallen apart in heat clearing away, be a kind of effective medicine preventing and treating cat dog tinea, easy to use, consumption is few; Its preparation method is simple, is applicable to the needs that large-scale industrial is produced.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese medicine composition preventing and treating cat dog tinea, be made up of Radix Stemonae, Cortex Phellodendri, natural Broneolum Syntheticum, Camphora and 75% (v/v) ethanol, wherein contain Radix Stemonae 12g, Cortex Phellodendri 10.5g, natural Broneolum Syntheticum 4.5g, Camphora 3g in 120ml75% (v/v) ethanol.
The preparation method of the Chinese medicine composition of above-mentioned control cat dog tinea, concrete preparation process is as follows:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, in Radix Stemonae 12g, Cortex Phellodendri 10.5g, first time adds 72ml75% (v/v) ethanol, Mi Gai, floods seven, collects impregnation liquid; In remaining slag charge, add remaining 75% (v/v) ethanol 48ml, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, add natural Broneolum Syntheticum 4.5g, Camphora 3g, mixing, to obtain final product.
Embodiment 2
A kind of Chinese medicine composition preventing and treating cat dog tinea, be made up of Radix Stemonae, Cortex Phellodendri, natural Broneolum Syntheticum, Camphora and 70% (v/v) ethanol, wherein contain Radix Stemonae 18g, Cortex Phellodendri 27g, natural Broneolum Syntheticum 9g, Camphora 3g in 243ml70% (v/v) ethanol.
The preparation method of the Chinese medicine composition of above-mentioned control cat dog tinea, concrete preparation process is as follows:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, in Radix Stemonae 18g, Cortex Phellodendri 27g, first time adds 121.5ml70% (v/v) ethanol, Mi Gai, floods seven, collects impregnation liquid; In remaining slag charge, add remaining 70% (v/v) ethanol 121.5ml, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, add natural Broneolum Syntheticum 3g, Camphora 1g, mixing, to obtain final product.
Embodiment 3
A kind of Chinese medicine composition preventing and treating cat dog tinea, be made up of Radix Stemonae, Cortex Phellodendri, natural Broneolum Syntheticum, Camphora and 75% (v/v) ethanol, wherein contain Radix Stemonae 9g, Cortex Phellodendri 6g, natural Broneolum Syntheticum 1g, Camphora 3g in 79ml75% (v/v) ethanol.
The preparation method of the Chinese medicine composition of above-mentioned control cat dog tinea, concrete preparation process is as follows:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, in Radix Stemonae 9g, Cortex Phellodendri 6g, first time adds 44ml75% (v/v) ethanol, Mi Gai, floods seven, collects impregnation liquid; In remaining slag charge, add remaining 75% (v/v) ethanol 35ml, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, add natural Broneolum Syntheticum 1g, Camphora 3g, mixing, to obtain final product.
Embodiment 4
A kind of Chinese medicine composition preventing and treating cat dog tinea, be made up of Radix Stemonae, Cortex Phellodendri, natural Broneolum Syntheticum, Camphora and 75% (v/v) ethanol, wherein contain Radix Stemonae 3.5g, Cortex Phellodendri 4g, natural Broneolum Syntheticum 1g, Camphora 0.5g in 40ml75% (v/v) ethanol.
The preparation method of the Chinese medicine composition of above-mentioned control cat dog tinea, concrete preparation process is as follows:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, in Radix Stemonae 3.5g, Cortex Phellodendri 4g, first time adds 22.5ml75% (v/v) ethanol, Mi Gai, floods seven, collects impregnation liquid; In remaining slag charge, add remaining 75% (v/v) ethanol 17.5ml, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, add natural Broneolum Syntheticum 1g, Camphora 0.5g, mixing, to obtain final product.
Embodiment 5
A kind of Chinese medicine composition preventing and treating cat dog tinea, be made up of Radix Stemonae, Cortex Phellodendri, natural Broneolum Syntheticum, Camphora and 70% (v/v) ethanol, wherein contain Radix Stemonae 7g, Cortex Phellodendri 7g, natural Broneolum Syntheticum 2g, Camphora 2g in 80ml70% (v/v) ethanol.
The preparation method of the Chinese medicine composition of above-mentioned control cat dog tinea, concrete preparation process is as follows:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, in Radix Stemonae 7g, Cortex Phellodendri 7g, first time adds 40ml70% (v/v) ethanol, Mi Gai, floods seven, collects impregnation liquid; In remaining slag charge, add remaining 70% (v/v) ethanol 40ml, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, add natural Broneolum Syntheticum 2g, Camphora 2g, mixing, to obtain final product.
The described Chinese crude drug of one of embodiment 1-5 is commercially available prod, and each amounts of components increased according to same ratio or reduce, the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The described Chinese crude drug of one of embodiment 1-5 all meets " Chinese veterinary pharmacopoeia " version two ministerial standard in 2010.
The composition principle of Chinese medicine composition of the present invention is: in side, Radix Stemonae returns lung meridian, cures mainly nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing, can outward for head louse, body louse, and enterobiasis, has resisting pathogenic microbes, insecticidal action; Cortex Phellodendri returns kidney, bladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat, has antifungic action; Natural Broneolum Syntheticum enters the heart, liver, lung meridian, logical all keys, and delicate fragrance a surname is loose, poison, removing nebula improving eyesight, reducing swelling and alleviating pain are fallen apart in heat clearing away, has antibacterial, antiinflammatory action; Camphora GUIXIN, spleen channel, have dehumidifying parasite killing, warming and odynolysis, have one's ideas straightened out and ward off dirty effect, cure mainly scabies pruritus, traumatic pain, toothache., there is antifungic action; 70%-75% (v/v) ethanol is used for disinfection.All medicines share, mutual Synergistic, and remarkably productive to control cat dog tinea, especially adopt proportioning described in embodiment 1, antibacterial anti-inflammatory, heat clearing away fall apart malicious effect very significantly, are particularly applicable to the control of cat dog tinea.
Clinical trial example:
Choose the cat dog that 20 infection have feline tinea disease, wherein,
12 infected dogs sporidiole bacterias; get by hair or skin scraping thing; observe under Wood's light, fur is green fluorescence, then with cyanogen potassium oxide hot solution digestion scraping thing; putting basis of microscopic observation has fungus to exist; pathological material of disease is inoculated in husky Bao Shi culture medium, and in incubated at room temperature 1-2 week, bacterium colony is chloroaniline bottom surface; shape of carefully perming, for Sabouraudites lanosus infects;
3 are infected microsporon gypseum, and pathological material of disease is inoculated in husky Bao Shi culture medium, and in incubated at room temperature 1-2 week, bacterium colony is buffs shape; Microscopy is shown in that macroconidium enriches, and oval to fusiformis, symmetry, wall are thin, coarse, have spinal; Microgonidium clavate, stockless the side being born in mycelia, for microsporon gypseum infects;
5 are infected palpus sporidiole bacteria, and pathological material of disease is inoculated in husky Bao Shi culture medium, and in incubated at room temperature 1-2 week, bacterium colony is brown base, and bottom surface is covered with fine particle bacterium colony, are to infect by sporidiole bacteria.
Treat with Chinese medicine composition described in the embodiment of the present invention 1, this Chinese medicine composition is applied in disease cat disease sites 3 times by every day, instill this medicinal liquid 5ml when having a bath weekly and coordinate cat dog bath lotion, use after one month, the diseased region of cat of catching an illness has very big improvement, and wherein, the sick cat improvement rate of 12 infected dogs sporidiole bacterias reaches 47%, 3 sick cat improvement rates infecting microsporon gypseum reach 100%, and 5 sick cat improvement rates infecting palpus sporidiole bacteria reach 40%.
Use Chinese medicine composition described in the embodiment of the present invention 1 to Healthy Cats dog, instill this medicinal liquid 3ml when having a bath weekly and coordinate cat dog bath lotion, use after one month, compare with blank group, sickness rate reduces 35%.
Above-mentioned reference embodiment is to this kind of detailed description of preventing and treating Chinese medicine composition of cat dog tinea and preparation method thereof and carrying out; illustrative instead of determinate; several embodiments can be listed according to institute's limited range; therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (5)
1. prevent and treat the Chinese medicine composition of cat dog tinea for one kind, it is characterized in that: be made up of Radix Stemonae, Cortex Phellodendri, natural Broneolum Syntheticum, Camphora and 70-75% (v/v) ethanol, wherein, Radix Stemonae 6-9g, Cortex Phellodendri 6-9g, natural Broneolum Syntheticum 1-3g, Camphora 1-3g is contained in every 79-81ml70-75% (v/v) ethanol.
2. the Chinese medicine composition of control cat dog tinea according to claim 1, is characterized in that: obtained by following method:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, according to the consumption flooding Radix Stemonae 6-9g, Cortex Phellodendri 6-9g in every 79-81ml70-75% (v/v) ethanol, add 70-75% (v/v) ethanol of percent by volume 50-60% for the first time, Mi Gai, flood seven, collect impregnation liquid; In remaining slag charge, add remaining 70-75% (v/v) ethanol, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, according to add in every 79-81ml70-75% (v/v) ethanol natural Broneolum Syntheticum 1-3g, Camphora 1-3g add natural Broneolum Syntheticum, Camphora with magnitude relation, mixing, to obtain final product.
3. the Chinese medicine composition of control cat dog tinea according to claim 1 and 2, is characterized in that: containing Radix Stemonae 7-8g, Cortex Phellodendri 7-8g, natural Broneolum Syntheticum 2-3g, Camphora 1-2g in every 79-80ml70-75% (v/v) ethanol.
4. the Chinese medicine composition of control cat dog tinea according to claim 3, is characterized in that: containing Radix Stemonae 8g, Cortex Phellodendri 7g, natural Broneolum Syntheticum 3g, Camphora 2g in every 80ml70-75% (v/v) ethanol.
5. the preparation method of the Chinese medicine composition of the control cat dog tinea that one of claim 1-4 is described, is characterized in that: concrete preparation process is as follows:
(1) get Radix Stemonae, Cortex Phellodendri powder is broken into coarse powder, contain in container, according to the consumption flooding Radix Stemonae 6-9g, Cortex Phellodendri 6-9g in every 79-81ml70-75% (v/v) ethanol, add 70-75% (v/v) ethanol of percent by volume 50-60% for the first time, Mi Gai, flood seven, collect impregnation liquid; In remaining slag charge, add remaining 70-75% (v/v) ethanol, Mi Gai, floods three, collects impregnation liquid, and the impregnation liquid collected with first time merges, and leaves standstill 24 hours, filters, obtains filtrate;
(2) get filtrate, according to add in every 79-81ml70-75% (v/v) ethanol natural Broneolum Syntheticum 1-3g, Camphora 1-3g add natural Broneolum Syntheticum, Camphora with magnitude relation, mixing, to obtain final product.
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CN110215483A (en) * | 2019-07-10 | 2019-09-10 | 陈丙乾 | A kind of Chinese medicine composition and preparation method thereof for preventing and treating dog cat tinea disease |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101347587A (en) * | 2008-08-29 | 2009-01-21 | 李孝银 | External-use Chinese medicine for treating itch and preparation method |
CN103386059A (en) * | 2013-07-25 | 2013-11-13 | 天津必佳药业集团有限公司 | Chinese medicine lotion for treating cat ringworm, and preparation method thereof |
-
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- 2014-06-30 CN CN201410306423.6A patent/CN105288380A/en active Pending
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101347587A (en) * | 2008-08-29 | 2009-01-21 | 李孝银 | External-use Chinese medicine for treating itch and preparation method |
CN103386059A (en) * | 2013-07-25 | 2013-11-13 | 天津必佳药业集团有限公司 | Chinese medicine lotion for treating cat ringworm, and preparation method thereof |
Non-Patent Citations (1)
Title |
---|
褚景生: "外用白芥子治疗小动物癣病和疥疮", 《动物科学与动物医学》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110215483A (en) * | 2019-07-10 | 2019-09-10 | 陈丙乾 | A kind of Chinese medicine composition and preparation method thereof for preventing and treating dog cat tinea disease |
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Application publication date: 20160203 |