CN105287705A - Traditional Chinese medicine preparation for specially treating difficult skin diseases and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for specially treating difficult skin diseases and preparation method thereof Download PDFInfo
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- CN105287705A CN105287705A CN201510696908.5A CN201510696908A CN105287705A CN 105287705 A CN105287705 A CN 105287705A CN 201510696908 A CN201510696908 A CN 201510696908A CN 105287705 A CN105287705 A CN 105287705A
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Abstract
The invention relates to an orally-taken traditional Chinese medicine preparation for specially treating difficult skin diseases and a preparation method thereof, in particular to an orally-taken traditional Chinese medicine compound preparation for treating the difficult skin diseases. The preparation is prepared from, by weight, potassium iodide, liquorice, bitter lotuses, snakeskin, radix aucklandiae, fructus gleditsiae, radix gentianae macrophyllae and disinfection clearwater. The preparation method specifically comprises the steps that 10-15 parts by weight of the potassium iodide is firstly added into a stirring tank, then 135-200 parts by weight of the disinfection clearwater is poured into the stirring tank, 15-25 parts by weight of decoctions prepared from a formula comprising liquorice, bitter lotuses, snakeskin, radix aucklandiae, fructus gleditsiae and radix gentianae macrophyllae are finally poured into the stirring tank, stirring is performed for 5 minutes until the mixed solutions are even, the mixed solutions are filled in soft capsules, and the preparation is obtained. The preparations have the advantages of being significant in treatment effect, simple and convenient in technology, low in cost, simple in clinical treatment and capable of effectively treating the intractable difficult skin diseases caused by various reasons and significantly enhancing the immunity of patients suffering from the difficult skin diseases.
Description
Technical field:
What patent of the present invention related to is the difficult dermopathic Chinese medicine preparation of a kind of specific treatment.Said preparation feature has specific treatment effect to difficult dermatosis, and can significantly improve the immunity of this dermatosis patient.
Technical background:
Skin covering is at body surface, human body one natural cover for defense, also be body resist various environmental stimuli (physics as ultraviolet, chemistry as detergent, machinery as friction, biological as sting) the first line of defence, therefore dermatosis is commonly encountered diseases, and patient can account for about 10% of general hospital Number of Outpatients usually.
Along with the development of society, the environment that people depend on for existence constantly changes, and along with atmospheric pollution is day by day serious, dermatosis sickness rate is improving constantly, and dermatosis paathogenic factor is also constantly upgraded.
world Health Organization (WHO) announces: dermatosis will be a kind of disease that in 21 century human history, sickness rate is the highest, disability rate is the highest, infectiousness is the strongest.particularly suppurate with intractable skin ulcer disease, tinea, exanthema, viral dermatitis, allergic dermatitis and the skin that causes thereof, flowing water, sufferings unbearably, fester that it is even more serious to bleed.In the modern life, dermatosis has become affects the beautiful and healthy important harm of patient, and dermatosis has become high morbidity, and enters the high-incidence season.
Medically, dermatosis is the disease about skin, is one of the commonly encountered diseases, frequently-occurring disease that have a strong impact on people ' s health, as leprosy, scabies, mycosis, bacterial skin infections etc.Dermatosis is that after skin (comprising hair and first) is subject to the impact of internal and external factor, its form, 26S Proteasome Structure and Function all change, and produces pathological process, and the various clinical priority performance of corresponding generation.Dermopathic sickness rate is very high, and its degree most is relatively lighter, also very not unhealthful, but its degree of a few peoples is heavier, and hindered greatly unhealthful, some is threat to life even.
Dermatosis is also a kind of common disease in China, and sickness rate is higher, and some not easily effects a radical cure, after curing also easily repeatedly.Classification important in domestic dermatosis comprises: fungal infection, eczema, bacteriological infection, the medication of seat skin ulcer, psoriasis etc.; Wherein, dermatosis antifungal agent is topmost dermatosis treating medicine, accounts for the over half of whole market.
Modern medical therapy dermatosis, using maximum is medicine for external use.Identical external used medicine has different dosage forms, as solution, paste, powder, cream, lotion, ointment, tincture and Emulsion etc.Different dosage forms, has different effects and indication, therefore according to the clinical symptoms of different stadium and skin lesion feature, should correctly select the medicine for external use of different dosage form.General acute stage local redness, vesicle, erosion time, multiselect solution soak, can play antiinflammatory, thermolysis; There is sepage person, first use solution soak, rear oil preparation.When skin lesion is in subacute stage, redness alleviates, sepage reduce, can take the circumstances into consideration to select paste, powder and lotion, can play antiinflammatory, antipruritic, convergence, protective effect.Chronic phase, skin lesion thickened, and during in lichenification, can select emulsifiable paste, ointment, plaster etc.If medicine for external use is selected or improper use, often invalid, even aggravate disease.
Naturopathy is also the Therapeutic Method that dermatosis is commonly used.Conventional physiotherapy has: electrotherapy, phototherapy, microwave therapy, cryotherapy, laser, hydrotherapy, X-ray therapy.But naturopathy way is the same with medicine for external use, often can only take stopgap measures, can not effect a permanent cure.
For a long time, for dermatosis particularly difficult dermopathic research and apply, numerous scholar in the industry, research worker and social relevant person particularly Chinese medicine circle extremely pay close attention to, obtained many achievements in research, patent of the present invention be namely one can specific treatment dermatosis particularly difficult dermopathic and there is the compound Chinese medicinal preparation medicine of " treating both the principal and secondary aspects of a disease " effect.
Summary of the invention: the present invention is to provide one can specific treatment dermatosis particularly difficult dermopathic and there is the compound Chinese medicinal preparation of " treating both the principal and secondary aspects of a disease " effect.It is characterized in that it does not wait the Chinese medicine of weight portion and sterilized pure water to form by following eight tastes, eight tastes do not wait the Chinese medicine of weight portion to be: potassium iodide, Radix Glycyrrhizae, bitter lotus, Periostracum Serpentis, the Radix Aucklandiae, Fructus Gleditsia, Qin Jiu, osteomiosis bone.
Patent of the present invention is achieved by the following technical programs, it is characterized in that concrete manufacture method is: first get 10-15 part by weight of potassium iodide and add in agitator tank, then the sterilized pure water of 135-200 weight portions is poured in this agitator tank, finally the decocting liquid concocted by each equivalent part Radix Glycyrrhizae, bitter lotus, Periostracum Serpentis, the Radix Aucklandiae, Fructus Gleditsia, Qin Jiu, osteomiosis bone 7 taste prepared slices of Chinese crude drugs prescription of 15-25 weight portions is poured in above-mentioned agitator tank, stir 5 minutes to even, load soft capsule, to obtain final product.The decocting liquid manufacture method concocted by each equivalent part Radix Glycyrrhizae, bitter lotus, Periostracum Serpentis, the Radix Aucklandiae, Fructus Gleditsia, Qin Jiu, osteomiosis bone 7 taste prepared slices of Chinese crude drugs prescription is, gets above each 7 taste group medicines of weight portion that wait and adds 8 times amount soak by water 2 times, each 1h; Filter, collecting decoction, to obtain final product.
Patent of the present invention has evident in efficacy, simple process, cheap feature, can specific treatment dermatosis particularly difficult dermopathic and there is " treating both the principal and secondary aspects of a disease " effect, and the immunity of dermatosis patient can be improved simultaneously.
By practice of pharmacy, capsule of the present invention can be prepared into various clinical pharmaceutical dosage form, comprise oral liquid, tablet, capsule, drop pill, granule, suspensoid, any one in skin drug-delivery preparation, injection, suppository, aerosol etc.
Patent of the present invention is achieved by following research:
One, pharma-toxicology experimentation, shows following result:
1, acute toxicity testing: mouse stomach maximum dosage-feeding is equivalent to 186 times of quantity, observing 14 days, there is not Novel presentation in animal, without dead.
2, long term toxicity test: to rat administration 24 weeks, low, in, the every Testing index of heavy dose of group no significant difference more equal to matched group; Convalescent period (drug withdrawal 4 weeks), its each dosage group indices compares no significant difference with matched group.The each internal organs of pathological examination are showed no the obvious toxic pathological change that this guiding drug rises.
Two, have passed the whole pharmacy researchs comprising preparation process research, quality standard research, stability study.
Three, clinical effectiveness significantly (the numerous patient of clinical cure, obvious effective rate and cure rate reach 98.6% and 93.8% respectively).
Claims (4)
1. difficult dermopathic Chinese medicine preparation of specific treatment and preparation method thereof, is characterized in that it forms by not waiting the potassium iodide of weight portion, Radix Glycyrrhizae, bitter lotus, Periostracum Serpentis, the Radix Aucklandiae, Fructus Gleditsia, Qin Jiu, osteomiosis bone, sterilized pure water.
2. difficult dermopathic Chinese medicine preparation of specific treatment and preparation method thereof, it is characterized in that concrete manufacture method is: first get 10-15 part by weight of potassium iodide and add in agitator tank, then the sterilized pure water of 135-200 weight portions is poured in this agitator tank, finally the decocting liquid concocted by each equivalent part Radix Glycyrrhizae, bitter lotus, Periostracum Serpentis, the Radix Aucklandiae, Fructus Gleditsia, Qin Jiu, osteomiosis bone 7 taste prepared slices of Chinese crude drugs prescription of 15-25 weight portions is poured in above-mentioned agitator tank, stir 5 minutes to even, load soft capsule, to obtain final product.
3. the decocting liquid manufacture method concocted by each equivalent part Radix Glycyrrhizae, bitter lotus, Periostracum Serpentis, the Radix Aucklandiae, Fructus Gleditsia, Qin Jiu, osteomiosis bone 7 taste prepared slices of Chinese crude drugs prescription is, gets above each 7 taste group medicines of weight portion that wait and adds 8 times amount soak by water 2 times, each 1h; Filter, collecting decoction, to obtain final product.
4. press practice of pharmacy, proprietary preparation of the present invention can be prepared into various clinical pharmaceutical dosage form, comprise the dosage form of oral formulations or parenterai administration, mainly refer to tablet, capsule, drop pill, granule, suspensoid, oral liquid, any one in percutaneous drug delivery agent, injection, suppository, aerosol etc..
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510696908.5A CN105287705A (en) | 2015-10-26 | 2015-10-26 | Traditional Chinese medicine preparation for specially treating difficult skin diseases and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510696908.5A CN105287705A (en) | 2015-10-26 | 2015-10-26 | Traditional Chinese medicine preparation for specially treating difficult skin diseases and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1381249A (en) * | 2001-04-13 | 2002-11-27 | 李捷 | Chinese patent medicine for treating venereal disease and puzzle dermatopathy |
| CN1739719A (en) * | 2005-09-17 | 2006-03-01 | 郭丽萍 | Dermatosis treating Chinese medicine prepn |
| CN1923244A (en) * | 2006-03-06 | 2007-03-07 | 王积善 | Medicinal composition for treating dermatosis, preparation process and use thereof |
-
2015
- 2015-10-26 CN CN201510696908.5A patent/CN105287705A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1381249A (en) * | 2001-04-13 | 2002-11-27 | 李捷 | Chinese patent medicine for treating venereal disease and puzzle dermatopathy |
| CN1739719A (en) * | 2005-09-17 | 2006-03-01 | 郭丽萍 | Dermatosis treating Chinese medicine prepn |
| CN1923244A (en) * | 2006-03-06 | 2007-03-07 | 王积善 | Medicinal composition for treating dermatosis, preparation process and use thereof |
Non-Patent Citations (3)
| Title |
|---|
| 周祯祥: "《中医常见病证用药举要》", 31 May 2004, 科学技术文献出版社 * |
| 张锦章: "《中西医结合皮肤性病治疗学》", 31 March 1992, 武汉出版社 * |
| 王硕: "《合理用药小窍门》", 31 October 2011, 中国中医药出版社 * |
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Application publication date: 20160203 |
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