CN105287477A - Carbasalate calcium powder and preparation method thereof - Google Patents
Carbasalate calcium powder and preparation method thereof Download PDFInfo
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- CN105287477A CN105287477A CN201510591738.4A CN201510591738A CN105287477A CN 105287477 A CN105287477 A CN 105287477A CN 201510591738 A CN201510591738 A CN 201510591738A CN 105287477 A CN105287477 A CN 105287477A
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- taurine
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- lactose
- carbasalate calcium
- calcium
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Abstract
The invention discloses carbasalate calcium powder and a preparation method thereof. The carbasalate calcium powder is prepared by mixing carbasalate calcium, lactose and taurine. The preparation method is characterized by including the steps of firstly, weighing the carbasalate calcium, lactose and taurine in parts by weight; secondly, drying the carbasalate calcium, lactose and taurine, respectively smashing the carbasalate calcium, lactose and taurine, and sieving with an 80-mesh sieve; thirdly, separating each of the carbasalate calcium, lactose and taurine into four equal groups, adding one group of lactose and one group of taurine after each group of carbasalate calcium is added according to an equivalent progressive adding method, and well mixing the raw materials to obtain the carbasalate calcium powder. The carbasalate calcium powder and the preparation method thereof have the advantages that the taurine can combine with the carbasalate calcium, enhance the liver to facilitate the metabolism of the carbasalate calcium in the liver, and perfectly supplement the antipyretic and antalgic effect of the carbasalate calcium.
Description
Technical field
The invention belongs to animal pharmaceuticals technical field, specifically, relate to a kind of Carbaspirin calcium powder and preparation method thereof.
Background technology
Carbasalate calcium soluble powder is mainly configured by carbasalate calcium and forms, and Main Function is antipyretic-antalgic, for heating and the alleviating pain of chicken.Carbasalate calcium is the salt of aspirin calcium and urea complexation, after the oral carbasalate calcium of chicken, is hydrolyzed to aspirin (aspirin), and aspirin absorbs fast, mainly through liver metabolism, in chicken body, degrades rapidly to salicylic acid.Through clinical application for many years and market feedback, this product is for the heating of chicken and alleviating pain Be very effective, but because carbasalate calcium is after animal is oral, the aspirin of hydrolysis is mainly through liver metabolism, and the animal that liver function is not strong, seriously can reduce its medicinal effects, and carbasalate calcium can not share with other alkalescent medicines again.
Summary of the invention
For solving above technical problem; the object of the present invention is to provide a kind of Carbaspirin calcium powder and preparation method thereof; find that taurine can not only share with carbasalate calcium; and can also strengthen liver be beneficial to the metabolism of carbasalate calcium in liver, perfect effect of supplementing carbasalate calcium antipyretic-antalgic simultaneously.
The present invention seeks to realize like this:
One, a Carbaspirin calcium powder, its key is to be mixed by component in following parts by weight:
Carbaspirin Ca45 part ~ 55 part, lactose 28 parts ~ 32 parts, taurine 18 parts ~ 22 parts.
Preferably, above-mentioned Carbaspirin calcium powder, is mixed by the component of following parts by weight: described carbasalate calcium 50 parts, lactose 30 parts, taurine 20 parts.
Preferably, above-mentioned Carbaspirin calcium powder, is mixed by the component of following parts by weight: described carbasalate calcium 50 parts, lactose 32 parts, taurine 19 parts.
Preferably, above-mentioned Carbaspirin calcium powder, is mixed by the component of following parts by weight: described carbasalate calcium 50 parts, lactose 29 parts, taurine 21 parts.
Two, a preparation method for Carbaspirin calcium powder, its key is to carry out according to the following steps:
(1) carbasalate calcium, lactose and taurine is taken by described parts by weight;
(2) first 80 mesh sieves were pulverized one by one by after carbasalate calcium, lactose and taurine drying;
(3) carbasalate calcium, lactose and taurine are divided into separately impartial 4 groups; then to progressively increase method by equivalent; often add one group of carbasalate calcium and just add one group of lactose and one group of taurine; each mixing 15 ~ 20 minutes; remix 30-45 minute after adding completely, raw material fully mixes and obtains Carbaspirin calcium powder.
Taurine of the present invention has strong liver choleretic effect, can remove cholestasis, can be conducive to the metabolism of carbasalate calcium in liver; Taurine itself also has antipyretic and antiinflammatory action, and its mechanism of action is by reducing body temperature to the effect of maincenter 5-ht system or catecholamine system, reaching perfect supplementary result to the antipyretic-antalgic effect of carbasalate calcium; Taurine can promote pituitary hormone secretion in addition, activation pancreatic function, thus improves the state of organism endocrine system, to organism metabolism with useful adjustment; And there is the enhancing of promotion organism immunity and the effect of resisting fatigue.
Beneficial effect:
A kind of Carbaspirin calcium powder of the present invention and preparation method thereof, taurine can not only share with carbasalate calcium, and can also strengthen liver be beneficial to the metabolism of carbasalate calcium in liver, perfect effect of supplementing carbasalate calcium antipyretic-antalgic simultaneously.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1:
A kind of Carbaspirin calcium powder, is mixed by component in following parts by weight:
Carbasalate calcium 50 parts, lactose 30 parts, taurine 20 parts.
A preparation method for Carbaspirin calcium powder, carry out according to the following steps:
(1) carbasalate calcium, lactose and taurine is taken by described parts by weight;
(2) first 80 mesh sieves were pulverized one by one by after carbasalate calcium, lactose and taurine drying;
(3) carbasalate calcium, lactose and taurine are divided into separately impartial 4 groups; then to progressively increase method by equivalent; often add one group of carbasalate calcium and just add one group of lactose and one group of taurine; each mixing 15 ~ 20 minutes; remix 30-45 minute after adding completely, raw material fully mixes and obtains Carbaspirin calcium powder.
Embodiment 2:
A kind of Carbaspirin calcium powder, is mixed by component in following parts by weight:
Carbasalate calcium 50 parts, lactose 32 parts, taurine 19 parts.
A preparation method for Carbaspirin calcium powder, carry out according to the following steps:
(1) carbasalate calcium, lactose and taurine is taken by described parts by weight;
(2) first 80 mesh sieves were pulverized one by one by after carbasalate calcium, lactose and taurine drying;
(3) carbasalate calcium, lactose and taurine are divided into separately impartial 4 groups; then to progressively increase method by equivalent; often add one group of carbasalate calcium and just add one group of lactose and one group of taurine; each mixing 15 ~ 20 minutes; remix 30-45 minute after adding completely, raw material fully mixes and obtains Carbaspirin calcium powder.
Embodiment 3:
A kind of Carbaspirin calcium powder, is mixed by component in following parts by weight:
Carbasalate calcium 50 parts, lactose 29 parts, taurine 21 parts.
A preparation method for Carbaspirin calcium powder, carry out according to the following steps:
(1) carbasalate calcium, lactose and taurine is taken by described parts by weight;
(2) first 80 mesh sieves were pulverized one by one by after carbasalate calcium, lactose and taurine drying;
(3) carbasalate calcium, lactose and taurine are divided into separately impartial 4 groups; then to progressively increase method by equivalent; often add one group of carbasalate calcium and just add one group of lactose and one group of taurine; each mixing 15 ~ 20 minutes; remix 30-45 minute after adding completely, raw material fully mixes and obtains Carbaspirin calcium powder.
Embodiment 4:
A kind of Carbaspirin calcium powder, is mixed by component in following parts by weight:
Carbaspirin Ca45 part, lactose 32 parts, taurine 18 parts.
A preparation method for Carbaspirin calcium powder, carry out according to the following steps:
(1) carbasalate calcium, lactose and taurine is taken by described parts by weight;
(2) first 80 mesh sieves were pulverized one by one by after carbasalate calcium, lactose and taurine drying;
(3) carbasalate calcium, lactose and taurine are divided into separately impartial 4 groups; then to progressively increase method by equivalent; often add one group of carbasalate calcium and just add one group of lactose and one group of taurine; each mixing 15 ~ 20 minutes; remix 30-45 minute after adding completely, raw material fully mixes and obtains Carbaspirin calcium powder.
Embodiment 5:
A kind of Carbaspirin calcium powder, is mixed by component in following parts by weight:
Carbasalate calcium 55 parts, lactose 28 parts, taurine 22 parts.
A preparation method for Carbaspirin calcium powder, carry out according to the following steps:
(1) carbasalate calcium, lactose and taurine is taken by described parts by weight;
(2) first 80 mesh sieves were pulverized one by one by after carbasalate calcium, lactose and taurine drying;
(3) carbasalate calcium, lactose and taurine are divided into separately impartial 4 groups; then to progressively increase method by equivalent; often add one group of carbasalate calcium and just add one group of lactose and one group of taurine; each mixing 15 ~ 20 minutes; remix 30-45 minute after adding completely, raw material fully mixes and obtains Carbaspirin calcium powder.
Embodiment 6:
A kind of Carbaspirin calcium powder, is mixed by component in following parts by weight:
Carbasalate calcium 50 parts, lactose 30 parts, taurine 20 parts.
A preparation method for Carbaspirin calcium powder, carry out according to the following steps:
(1) carbasalate calcium, lactose and taurine is taken by described parts by weight;
(2) first 80 mesh sieves were pulverized one by one by after carbasalate calcium, lactose and taurine drying;
(3) carbasalate calcium, lactose and taurine are divided into separately impartial 4 groups; then to progressively increase method by equivalent; often add one group of carbasalate calcium and just add one group of lactose and one group of taurine; each mixing 15 ~ 20 minutes; remix 30-45 minute after adding completely, raw material fully mixes and obtains Carbaspirin calcium powder.
Finally it should be noted that; foregoing description is only the preferred embodiments of the present invention; those of ordinary skill in the art is under enlightenment of the present invention; under the prerequisite without prejudice to present inventive concept and claim; can make like multiple types and representing, such conversion all falls within protection scope of the present invention.
Claims (5)
1. a Carbaspirin calcium powder, is characterized in that being mixed by component in following parts by weight: Carbaspirin Ca45 part ~ 55 part, lactose 28 parts ~ 32 parts, taurine 18 parts ~ 22 parts.
2. Carbaspirin calcium powder according to claim 1, is characterized in that being mixed by the component of following parts by weight: described carbasalate calcium 50 parts, lactose 30 parts, taurine 20 parts.
3. Carbaspirin calcium powder according to claim 1, is characterized in that being mixed by the component of following parts by weight: described carbasalate calcium 50 parts, lactose 32 parts, taurine 19 parts.
4. Carbaspirin calcium powder according to claim 1, is characterized in that being mixed by the component of following parts by weight: described carbasalate calcium 50 parts, lactose 29 parts, taurine 21 parts.
5. a preparation method for the Carbaspirin calcium powder described in any one of Claims 1 to 4, is characterized in that carrying out according to the following steps:
(1) carbasalate calcium, lactose and taurine is taken by described parts by weight;
(2) first 80 mesh sieves were pulverized one by one by after carbasalate calcium, lactose and taurine drying;
(3) carbasalate calcium, lactose and taurine are divided into separately impartial 4 groups, then to progressively increase method by equivalent, often add one group of carbasalate calcium and just add one group of lactose and one group of taurine, mixing 30-45 minute, raw material fully mixes and obtains Carbaspirin calcium powder.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106389454A (en) * | 2016-08-30 | 2017-02-15 | 瑞普(天津)生物药业有限公司 | Compound erythromycin thiocyanate soluble powder for livestock and preparation method therefor |
CN106491538A (en) * | 2016-12-05 | 2017-03-15 | 郑州百瑞动物药业有限公司 | carbasalate calcium soluble powder and preparation method thereof |
CN107616970A (en) * | 2017-10-19 | 2018-01-23 | 洛阳瑞华动物保健品有限公司 | A kind of carbasalate calcium soluble powder and preparation method thereof |
CN108210459A (en) * | 2016-12-13 | 2018-06-29 | 河南后羿实业集团有限公司 | A kind of carbasalate calcium Liposomal formulation and preparation method thereof |
CN108606953A (en) * | 2016-12-13 | 2018-10-02 | 河南后羿实业集团有限公司 | A kind of anti-caking compound carbasalate calcium pulvis and preparation method thereof |
Citations (3)
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CN101695490A (en) * | 2009-08-07 | 2010-04-21 | 天津生机集团股份有限公司 | Medicinal composition for treating livestock and poultry cold, preparation method thereof and application thereof |
CN102924335A (en) * | 2012-11-13 | 2013-02-13 | 齐鲁动物保健品有限公司 | Preparation method of carbasalate calcium |
CN104688760A (en) * | 2015-02-02 | 2015-06-10 | 山东省中医药研究院 | Pharmaceutical composition composed of saikoside A and taurine and use thereof |
-
2015
- 2015-09-16 CN CN201510591738.4A patent/CN105287477A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101695490A (en) * | 2009-08-07 | 2010-04-21 | 天津生机集团股份有限公司 | Medicinal composition for treating livestock and poultry cold, preparation method thereof and application thereof |
CN102924335A (en) * | 2012-11-13 | 2013-02-13 | 齐鲁动物保健品有限公司 | Preparation method of carbasalate calcium |
CN104688760A (en) * | 2015-02-02 | 2015-06-10 | 山东省中医药研究院 | Pharmaceutical composition composed of saikoside A and taurine and use thereof |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106389454A (en) * | 2016-08-30 | 2017-02-15 | 瑞普(天津)生物药业有限公司 | Compound erythromycin thiocyanate soluble powder for livestock and preparation method therefor |
CN106491538A (en) * | 2016-12-05 | 2017-03-15 | 郑州百瑞动物药业有限公司 | carbasalate calcium soluble powder and preparation method thereof |
CN106491538B (en) * | 2016-12-05 | 2019-01-08 | 郑州百瑞动物药业有限公司 | carbasalate calcium soluble powder and preparation method thereof |
CN108210459A (en) * | 2016-12-13 | 2018-06-29 | 河南后羿实业集团有限公司 | A kind of carbasalate calcium Liposomal formulation and preparation method thereof |
CN108606953A (en) * | 2016-12-13 | 2018-10-02 | 河南后羿实业集团有限公司 | A kind of anti-caking compound carbasalate calcium pulvis and preparation method thereof |
CN107616970A (en) * | 2017-10-19 | 2018-01-23 | 洛阳瑞华动物保健品有限公司 | A kind of carbasalate calcium soluble powder and preparation method thereof |
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Application publication date: 20160203 |