CN105286986A - Catheter ablation device and electrode radiofrequency ablation catheter thereof - Google Patents

Catheter ablation device and electrode radiofrequency ablation catheter thereof Download PDF

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Publication number
CN105286986A
CN105286986A CN201410369680.4A CN201410369680A CN105286986A CN 105286986 A CN105286986 A CN 105286986A CN 201410369680 A CN201410369680 A CN 201410369680A CN 105286986 A CN105286986 A CN 105286986A
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electrode
fill orifice
catheter
diameter
ablation catheter
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CN105286986B (en
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张清淳
梁波
郭小静
王慧
孙毅勇
谭家宏
山鹰
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Shanghai Microport EP MedTech Co Ltd
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Shanghai Microport EP MedTech Co Ltd
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Abstract

The invention relates to an electrode radiofrequency ablation catheter. The electrode radiofrequency ablation catheter comprises an annular segment and a plurality of electrodes, wherein the annular segment is positioned at the far end of the catheter, a fluid perfusion passage is arranged in the annular segment, the electrodes are arranged on the annular segment at intervals, and each electrode is provided with a plurality of small holes which allow fluid to flow out and are communicated with the fluid perfusion passage through perfusion holes. The diameter of each perfusion hole corresponding to the corresponding electrode is d(n), n refers to an electrode sequence number, the smaller the distance from the electrodes to the tail end of the catheter is, the larger the n is, and d(n) increases along with increase of the n. Through the design, flow quantity difference among the perfusion holes can be decreased, so that flow of the perfusion holes tends to be even.

Description

Catheter ablation device and electrode radio-frequency ablation catheter thereof
Technical field
The present invention relates to a kind of conduit, especially relate to a kind of electrode radio-frequency ablation catheter.
Background technology
Radio frequency ablation catheter is a kind of electrophysiologicalcatheter catheter, and it is widely used in treating arrhythmia in recent years.In general, conduit comprises the mapping signal of telecommunication and radio-frequency (RF) ablation two functions.Conduit enter intracardiac after, first mapping is carried out to the signal of telecommunication, determines that abnormal path or abnormal electric shock are moved a little, afterwards isolation is melted to these aberrant electrical signals paths, thus reach the object for the treatment of.
Atrial fibrillation is a kind of common arrhythmia, is that cardiac muscle loses normal and regular diastole campaign, and replaces quick and inharmonic faint wriggling, thus make atrium lose normal contraction.1997, cardiology professor meter Xie Erayisagaier etc. proposed the genesis mechanism of atrial fibrillation mainly from the triggering of the fast electric excitement of pulmonary vein sleeve.By the method for radio-frequency (RF) ablation pulmonary vein to be connected with the dissection in atrium or conductivity relation is isolated, the object for the treatment of can be reached.
In traditional radiofrequency ablation therapy, the far-end of ablation catheter (be namely used for implement operation one end) is single electrode, and what melt rear generation point-like melts stove.Linear melt stove if formed, can only drag lentamente in the process melted.Consider art cardiac continue beat, effective linear ablation stove be formed very high to the requirement of patient, and often can not form continuous print and melt stove, thus cause the failure isolated.The mode becoming multi-electrode to arrange the remote design of ablation catheter is proposed for this reason.These electrodes are typically spaced circlewise.When treating, multiple electrode melts orifices of pulmonary veins jointly, and what can obtain ring-type melts stove.
In ablation procedure, perfusion cooling is carried out to electrode and can improve the safety and efficiency of melting significantly.In actual applications, how to make the efficiency of perfusion improve, as how made the flow that on electrode, aperture is discharged identical, how obtaining best cooling-down effect etc. with minimum flow, is a problem mainly considered.Be in unipolar ablation catheter at far-end, had by electrode, guide-tube structure is optimized the scheme that design improves perfusion effect.But be in the ablation catheter of multi-electrode arrangement at far-end, also lack the design that can improve perfusion effect.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of electrode radio-frequency ablation catheter, has the perfusion effect of improvement.
The present invention is that to solve the problems of the technologies described above the technical scheme adopted be a kind of electrode radio-frequency ablation catheter, comprises circular segment and multiple electrode.Circular segment is positioned at this distal end of catheter, has fluid perfusion channel in this circular segment.Be arranged in multiple electrode gap in this circular segment, each electrode offers multiple aperture flowed out for fluid, and the plurality of aperture be by fill orifice and this fluid perfusion channel connection.Wherein, be electrode sequence number and larger the closer to this catheter tip n if the diameter of the fill orifice corresponding to each electrode is d (n), n, then d (n) increases with n and increases.
In one embodiment of this invention, the adjustable extent of the diameter of this circular segment is between 10-40mm.
In one embodiment of this invention, electrode sum is between 4-10.
In one embodiment of this invention, the little hole number on each electrode is 5-100.
In one embodiment of this invention, each hole diameter on each electrode is between 0.03-0.3mm.
In one embodiment of this invention, the quantity of the fill orifice corresponding to each electrode is 1-3.
In one embodiment of this invention, the diameter of each fill orifice is between 0.1-0.6mm.
In one embodiment of this invention, a fill orifice answered by each electrode pair, and the uniform diameter of each fill orifice increases progressively.
In one embodiment of this invention, a fill orifice answered by each electrode pair, and the diameter d (n) of each fill orifice=A+Bn+Cn 2, wherein
A=A1-A2*N, A1 are between 1.07 ~ 1.09, and A2 is between 0.02 ~ 0.03;
B=B1-B2*N, B1 are between 0.08 ~ 0.10, and B2 is between 0.001 ~ 0.003;
C=C1*N+C2, C1 are between 0.0001 ~ 0.001, and C2 is between 0.0001 ~ 0.001;
N is the sum of electrode.
In one embodiment of this invention, 2 fill orifices answered by least part of electrode pair.
In one embodiment of this invention, the electrode of corresponding 2 fill orifices is positioned at catheter tip.
The present invention separately proposes a kind of catheter ablation device, comprises multielectrode recoding ablation catheter as above.
The present invention, owing to adopting above technical scheme, makes it compared with prior art, by being optimized the diameter of each fill orifice, the flow difference of each fill orifice can being made to reduce, thus allow the flow of each fill orifice be tending towards even.
Accompanying drawing explanation
For above-mentioned purpose of the present invention, feature and advantage can be become apparent, below in conjunction with accompanying drawing, the specific embodiment of the present invention is elaborated, wherein:
Fig. 1 illustrates catheter ablation device and the radio frequency ablation catheter schematic diagram thereof of one embodiment of the invention.
Fig. 2 illustrates the circular segment schematic diagram of the radio frequency ablation catheter of one embodiment of the invention.
Fig. 3 illustrates the electrode structure of the circular segment of one embodiment of the invention.
Fig. 4 illustrates the axial section of the circular segment of one embodiment of the invention.
Fig. 5 illustrates the circular segment longitudinal section view of one embodiment of the invention.
Fig. 6 illustrates the fill orifice schematic diagram of the circular segment of one embodiment of the invention.
Fig. 7 illustrates the fill orifice schematic diagram of the circular segment of another embodiment of the present invention.
Fig. 8 illustrates the circular segment longitudinal section view of another embodiment of the present invention.
Fig. 9 A is that the radio frequency ablation catheter of the embodiment of the present invention enters left atrial ablation schematic diagram.
Fig. 9 B be the continuous print ring-type that formed at orifices of pulmonary veins of the radio frequency ablation catheter of the embodiment of the present invention melt stove.
Detailed description of the invention
With reference now to accompanying drawing, describe theme required for protection, in whole accompanying drawing, use identical reference number to refer to identical element.In the following description, for the purpose of explaining, set forth numerous detail to provide the complete understanding to theme required for protection.But it is evident that, these themes also can not adopt these details to implement.
Embodiments of the invention describe a kind of catheter ablation device and radio frequency ablation catheter thereof, and it is by improving perfusion effect to the optimal design of fill orifice.
Fig. 1 illustrates catheter ablation device and the radio frequency ablation catheter schematic diagram thereof of one embodiment of the invention.Shown in figure 1, ablating device 100 has radiofrequency melting instrument 110, buttock line 120, operating grip 130, intrusion pipe 140 and ablation catheter 150.Radiofrequency melting instrument 110 is connected to operating grip 130 by buttock line 120, to provide energy by operating grip 130 to the electrode on ablation catheter 150.Intrusion pipe 140 is also connected to operating grip 130, provides infusion liquid by operating grip 130 to ablation catheter 150 far-end, gives electrode perfusion when melting.In addition, ablation catheter 150 is connected to operating grip 130, and carries out ablative surgery under the operation of operating grip 130.
Continue with reference to shown in figure 1, ablation catheter 150 comprises main body 151, extension 152 and circular segment 153.Main body 151 one end is connected to operating grip 130, and the other end connects extension 152.End in extension 152 connects circular segment 153.Like this, main body 151, extension 152 are connected successively with circular segment, form one section of complete conduit.
In an embodiment of the present invention, the material of ablation catheter 150 is generally made by polyurethane (TPU) material, but also can be made by other thermoplasticity materials, such as nylon elastomer (PEBAX).The caliber of ablation catheter 150 does not have particular requirement, but is generally no more than 9Fr (3Fr=1mm).
Fig. 2 illustrates the circular segment schematic diagram of the radio frequency ablation catheter of one embodiment of the invention.Shown in figure 2, circular segment 153 is similar to rounded, but is not close completely, but becomes substantially closed shape by distal end of catheter natural torsion.The diameter of circular segment 153 can be regulated by joystick 130.For example, diameter range is 10-40mm.
Multiple electrode 154 compartment of terrain is arranged in circular segment 153.Conform to the shape of circular segment 153, thus these electrodes 154 are also arranged in ring-type substantially.In an embodiment of the present invention, the quantity of electrode can be 4-10.The length of electrode can be 2-4mm, and be preferably 3mm, the arrangement pitch between electrode and electrode can be 3-10mm, is preferably 7mm.
Fig. 3 illustrates the electrode structure of the circular segment of one embodiment of the invention.In conjunction with reference to shown in figure 3, electrode 154 has multiple aperture 1541, for pouring into water outlet, the diameter of aperture, between 0.03-0.3mm, is preferably 0.08mm.Little hole number can be 5-100, is preferably 20.
Fig. 4 illustrates the axial section of the circular segment of one embodiment of the invention.Fig. 5 illustrates the circular segment longitudinal section view of one embodiment of the invention.With reference to shown in Figure 4 and 5, in radio frequency ablation catheter 150, be provided with the first chamber 1501, second chamber 1502, the 3rd chamber 1506 and the 4th chamber 1508.
First chamber 1501 is perfusion channel, is used for setting up the passage of electrode perfusion.First chamber 1501 is communicated with electrode 154 by fill orifice 1510.When the external world has water to pour into, water enters electrode 154 through the first chamber 1501, fill orifice 1510, then is flowed out by the aperture 1541 on electrode 154.
Sizing line 1503 and annular constrictions line 1504 is placed in second chamber 1502.The material of sizing line 1503 is preferably Nitinol, can be shaped into annular or helical annular in advance, circular segment 153 can be made after being put in chamber like this to circularize or helical annular.Sizing line 1503 is placed in protecting tube 1505 with annular constrictions line 1504.The material of protecting tube 1505 can be polyimides (PI), also can be politef (PTFE).
Electrodes wire 1507 in 3rd chamber 1506.Punch between the 3rd chamber 1506 and electrode 154, electrode cable 1507 passing hole is welded with electrode 154.After connection, with glue or epoxy resin, hole is closed.At this, the size in hole is by electrode cable 1507.
The wire 1509 of magnetic inductor (not shown) is placed in 4th chamber 1508.At this, magnetic inductor can be positioned over the distalmost end of circular segment 153, is used for the treatment of the position of middle identification conduit.
In the present embodiment, the diameter of the first chamber 1501 is 0.5-1 millimeter, is preferably 0.8 millimeter.The not specific requirement of diameter of other three chambers, can place the space that each chamber requires cable.
The connection diagram of electrode 154 and circular segment 153 can be found out from Fig. 4 and Fig. 5.Electrode 154 is placed on outside circular segment 153.Electrode 154 can have the protrusion 154a of central authorities and the contact site 154b of both sides.Electrode 154 is contacted with circular segment 153 by the contact site 154b of both sides.Can at the edge of contact site 154b and circular segment 153 intersection gluing, to be fixed in circular segment 153.Electrode 154 be then distributed in protrusion 154a for the aperture poured into, as shown in Figure 3.
As shown in Figure 4, the corresponding fill orifice 1510 in position that electrode 154 is fixing.Water in first chamber 1501 can enter electrode 154 through fill orifice 1510, then sprays from each aperture of electrode 154.In order to improve perfusion effect, the size of embodiments of the invention to the fill orifice at each electrode place is optimized design.Summarily say, each electrode can to there being fill orifice (Fig. 4 example 1).If electrode sequence number is n, and larger the closer to this catheter tip n.With reference to figure 2, be 10 near the electrode sequence number of catheter tip, therefore electrode label is 154_10, and in the beginning of conduit circular segment, electrode sequence number is 1.In other words, from the beginning of circular segment, electrode sequence number is 1,2,3 ..., n.N can be 4-15.In addition, if the overall diameter of the fill orifice corresponding to each electrode is d (n), then d (n) increases with n and increases.It is pointed out that this increase is not strictly monotone increasing, on the contrary, the overall diameter of the fill orifice of adjacent electrode can be equal or almost equal.
At this, diameter r can along with the increase of electrode sequence number uniform increments, also can along with the increase of electrode sequence number but not uniform increments.For non-homogeneous increasing progressively, answer the embodiment of a fill orifice at each electrode pair under, if find that the diameter r of each fill orifice and electrode sequence number n meets binomial relation substantially, then the uniform flow degree at each fill orifice place is better.
Specifically, diameter d (n)=A+Bn+Cn 2, wherein A, B, C are the variable relevant with electrode sum N, and n is electrode sequence number.Further, A, B, C and N meet following relation:
A=A1-A2*N, A1 are between 1.07 ~ 1.09, and A2 is between 0.02 ~ 0.03;
B=B1-B2*N, B1 are between 0.08 ~ 0.10, and B2 is between 0.001 ~ 0.003;
C=C1*N+C2, C1 are between 0.0001 ~ 0.001, and C2 is between 0.0001 ~ 0.001.
In the process obtaining variables A, from the respective scope of A1, A2, obtain a value as constant A1, A2, try to achieve N in conjunction with electrode sum.In like manner, B, C is tried to achieve.Then can in the hope of fill orifice diameter d (n) corresponding to each electrode sequence number.
Analog result shows, meets the diameter of above-mentioned relation, the flow standard variance of each fill orifice can be controlled in 1.If the uniform diameter of each fill orifice increases progressively, then the flow standard variance of each fill orifice generally can more than 1 less than 1.5.By contrast, if the diameter of each fill orifice is identical, then the flow standard variance of each fill orifice can more than 2.
Fig. 6 illustrates the fill orifice schematic diagram of the circular segment of one embodiment of the invention.Shown in figure 6, the label of 10 electrodes is respectively 154_1,154_2,154_3 ..., 154_10, correspondingly fill orifice label is respectively 1510_1,1510_2,1510_3 ..., 1510_10.If the diameter of each fill orifice is r (1) respectively, r (2), r (3) ..., r (10), then have: r (1)≤r (2)≤r (3)≤... ,≤r (10).That is, electrode sequence number is larger, then the diameter of fill orifice is less.
The advantage of this design can be quoted as proof from hydrodynamics.According to fluid mechanics equation, Bernoulli equation:
P 0 + 1 2 ρv 0 2 = P 1 + 1 2 ρv 1 2 + ω 1
Be the pressure of fill orifice at this P, ρ is fluid density, and v is the flow velocity at fill orifice place, and ω is frictional dissipation.
In this example, convection cell entrance and arbitrary fill orifice place can use Bernoulli equation, that is:
P 0 + 1 2 ρv 0 2 = P 1 + 1 2 ρv 1 2 + ω 1 (fill orifice 1)
P 0 + 1 2 ρv 0 2 = P 2 + 1 2 ρv 2 2 + ω 2 (fill orifice 2)
...
P 0 + 1 2 ρv 0 2 = P 10 + 1 2 ρv 10 2 + ω 10 (fill orifice 10)
In order to obtain best perfusion effect, the outflow total amount of each fill orifice should be equal, that is:
Q 1=Q 2=Q 3……=Q 10
And under same traffic, the static pressure that each electrode gives fill orifice is identical, that is:
P 1=P 2=P 3……=P 10
According to r is fill orifice radius,
Substitute into Bernoulli equation: P 0 - P 1 + 1 2 ρ ( Q 0 π r 0 2 ) 2 = 1 2 ρ ( 1 4 Q 0 π r 1 2 ) 2 + w 1 = C
Because ω 1< ω 2< ω 10,
Therefore, if r (1)≤r (2)≤r (3)≤... ,≤r (10), then can offset this variation tendency of w, make and the flow at fill orifice place trends towards equal.
The result simulated in software below in conjunction with concrete example is to illustrate implementation result of the present invention.Simulate with Flowsimulation in software solidworks, the exit static pressure of fill orifice is set to 103997.52Pa, and inlet flow rate is set to 60ml/min.Following table 1 illustrates fill orifice diameter and the discharge relation of circular segment.
Table 1
As shown in Table 1, when the diameter of each fill orifice all identical (example 1), discharge rate is more and more slower, and the flow of each fill orifice is all uneven, and overall variance reaches 2.23, can not reach uniform perfusion effect.If adjust the diameter of each fill orifice, increase gradually from water inlet to end, then the uniformity of groundwater increment is significantly improved, and in several example 2-6, overall variance is respectively 1.34,0.82,0.71,0.64 and 0.41.The wherein example that increases progressively for uniform diameter of example 2, example 3-6 is the non-homogeneous example increased progressively of diameter.Therefore no matter diameter is uniform increments or non-homogeneously increases progressively, and all can significantly improve discharge uniformity.Further, if according to non-homogeneous incremental manner, improve discharge uniformity and more breathe out.For example, under non-homogeneous incremental manner, mutual diameter proportion is r1:r2:r3:r4:r5:r6:r7:r8:r9:r10=1:(1.00-1.05): (1.10-1.13): (1.14-1.20): (1.25-1.35): (1.35-1.40): (1.51-1.60): (1.70-1.80): (1.85-1.95): (2.00-2.20).
More preferably, be r1:r2:r3:r4:r5:r6:r7:r8:r9:r10=1:1.08:1.19:1.35:1.38:1.5 77:1.73:1.92:2.
Further, the design of diameter preferably considers flow velocity simultaneously, because expect that the glassware for drinking water flowed out from hole has larger flow velocity, forms water spray effect.Following table 2 illustrates fill orifice diameter and the flow velocity relation of circular segment.
Table 2
In above-mentioned each example, example 3 has relatively large flow velocity 0.61m/s in the 10th hole of end, is therefore better selection.
In another embodiment of the invention, the quantity of fill orifice can be 9, and correspondingly diameter design is as follows:
Table 3
Above-mentioned example 1,2,3 are respectively same diameter, the design of uniform increments diameter and the uneven diameter increased progressively, and the flow variance of the correspondence of three kinds is respectively 4.14,0.80 and 0.40.Can see, no matter diameter is uniform increments or non-homogeneously increases progressively, and all can significantly improve discharge uniformity.By contrast, the irregular diameter increased progressively has better discharge uniformity.For example, under non-homogeneous incremental manner, diameter ratio is: (1-1.65) .3:(1.20-1.30): (1.35-1.45): (1.-1.95): (1.90-2.30): (2.10-2.60) 0): (2.55-2.65): (2.8-3.1).
When following table 4 illustrates that the quantity of the fill orifice of circular segment is 9, fill orifice diameter and flow velocity relation.
Table 4
In above-mentioned each example, example 2-3 has relatively large flow velocity 0.78m/s and 0.60m/s at the 9th Kong Jun of end, is therefore all feasible selection.
In another embodiment of the invention, the quantity of fill orifice can be 7, and correspondingly diameter design is as follows:
Table 5
Above-mentioned example sample 1 is the design of same diameter, and its variance is 4.20, sample 2, and the design of 3 uneven diameters increased progressively respectively, flow variance is respectively 0.43 and 0.48.Can see that no matter diameter is uniform increments or non-homogeneously increases progressively, and all can significantly improve discharge uniformity.By contrast, the irregular diameter increased progressively has better discharge uniformity.For example, under non-homogeneous incremental manner, diameter ratio is: (1-1.65) .3:(1.20-1.30): (1.35-1.45): (1.-1.95): (1.90-2.30): (2.10-2.60) 0): (2.55-2.65): (2.8-3.1).
When following table 6 illustrates that the quantity of the fill orifice of circular segment is 7, fill orifice diameter and flow velocity relation.
Table 6
In above-mentioned each example, example 2-3 has relatively large flow velocity 1.05m/s and 0.78m/s at the 7th Kong Jun of end, is therefore all feasible selection.By contrast, in the non-homogeneous example increased progressively of diameter, flow velocity is better.
In another embodiment of the invention, the quantity of fill orifice can be 4, and correspondingly diameter design is as follows:
Table 7
Above-mentioned example sample 1 is the design of same diameter, and its variance is 3.31, sample 2, and the design of 3 uneven diameters increased progressively respectively, flow variance is respectively 1.11 and 0.27.Can see that no matter diameter is uniform increments or non-homogeneously increases progressively, and all can significantly improve discharge uniformity.By contrast, the irregular diameter increased progressively has better discharge uniformity.
The present invention does not limit each electrode pair and answers a fill orifice.That is, each electrode can the more fill orifices of correspondence, such as 2-3 fill orifice.Especially, if one or more electrodes of catheter tip use multiple fill orifice, the flow between the fill orifice of each electrode can be allowed more even, and the fill orifice flow velocity of electrode of distal end of catheter can be improved.
When the fill orifice on an electrode is replaced with multiple fill orifice, can implement according to following conversion relation:
π R 2=n π r 2(diameter when R is single fill orifice, can be obtained by above-mentioned calculating formula, the number of fill orifice when n is multiple fill orifice, the diameter of fill orifice during r=many fill orifices)
Then r = R n .
Enumerate the situation of corresponding 2 fill orifices of partial electrode below.
Fig. 7 illustrates the fill orifice schematic diagram of the circular segment of another embodiment of the present invention.Shown in figure 7, the label of 10 electrodes is respectively 254_1,254_2,254_3 ..., 254_10, correspondingly fill orifice label is respectively 2510_1,2510_2,2510_3 ..., 2510_10.If the gross area of each fill orifice is s1, s2, s3 respectively ..., s10, then have: s1≤s2≤s3≤... ,≤s10.That is, electrode sequence number is larger, then the gross area of fill orifice is less.Particularly, on one or several electrode of distal end of catheter, such as electrode 254_7,254_8,254_9 and 254_10 carry out diplopore design, and the gross area of its fill orifice is s7, s8, s9, s10.Following table 8 illustrates fill orifice diameter and the discharge relation of circular segment.
Table 8
Example 1-3 above can allow the flow between fill orifice more even (overall variance <0.6), in table 8.In addition, the design of holes is adopted can to ensure that can have effect of well spraying water, the speed namely sprayed is large under identical input flow rate (60ml/min).Following table 9 illustrates fill orifice diameter and the flow velocity relation of circular segment.
Table 9
Contrast table 9 and table 1 can be found out, under diplopore design, even if in the slowest hole 10 of flow velocity, also have the flow velocity of more than 0.83m/s, apparently higher than the flow velocity of single hole design lower opening 10.
For the situation of 10 electrodes, if carry out diplopore design, the total area ratio of each electrode lower opening should at s (1): s (2): s (3): s (4): s (5): s (6): s (7): s (8): s (9): s (10)=1:(1-1.2): (1.15-1.30): (1.35-1.50): (1.6-2): (1.9-2.1): (2.15-2.40): (2.35-2.70): (2.70-2.95): (2.85-2.95); Preferably, s (1): s (2): s (3): s (4): s (5): s (6): s (7): s (8): s (9): s (10) are 1:1:1.17:1.36:1.56:2.01:2.18:2.34:2.72:2.92.
Be appreciated that according to flow velocity needs, can just bring into use in less electrode sequence number diplopore to design.Such as from the 6th electrode, just use diplopore design.Certainly, also diplopore can be brought into use to design from larger electrode sequence number.Such as from the 8th electrode, diplopore is just brought into use to design.
Be appreciated that the embodiment for having more or less electrode, diplopore design remains applicable, no longer launches to describe at this.
Correspondingly, Fig. 8 illustrates the circular segment longitudinal section view of another embodiment of the present invention.With reference to figure 8, below a certain electrode 254, corresponding two fill orifices 2510, are all communicated with the first chamber 2501.
Fig. 9 A is that radio frequency ablation catheter enters intracardiac process of carrying out melting.General process is, guiding sheath 910 enters intracardiac through femoral vein, postcava, pass through atrial septal puncture, guiding sheath 910 enters left atrium 902 (be arranged in figure right side, left side is right atrium 901), and loop-like ablation conduit 150 enters left atrium 902 by guiding sheath 150, under the help of X-ray, be positioned over the ostium venosum cordis of pulmonary vein 903 through operation handlebar loop-like ablation conduit 150, melt, what form annular melts stove 920 (Fig. 9 B).Afterwards, successively other three orifices of pulmonary veins are melted, finally obtain pulmonary venous isolation.
Radio frequency ablation catheter described by the above embodiment of the present invention is compared, and by being optimized the diameter of each fill orifice, the flow difference of each fill orifice can being made to reduce, thus allow the flow of each fill orifice be tending towards even.Further, by carrying out diplopore design to part fill orifice, the present invention can allow the flow velocity of each fill orifice obviously reduce, and maintains the ejection effect of infusion liquid.
Although the present invention describes with reference to current specific embodiment, but those of ordinary skill in the art will be appreciated that, above embodiment is only used to the present invention is described, change or the replacement of various equivalence also can be made when not departing from spirit of the present invention, therefore, as long as all will drop in the scope of claims of the application the change of above-described embodiment, modification in spirit of the present invention.

Claims (12)

1. an electrode radio-frequency ablation catheter, comprising:
Circular segment, is positioned at this distal end of catheter, has fluid perfusion channel in this circular segment;
Multiple electrode, compartment of terrain is arranged in this circular segment, each electrode offers multiple aperture flowed out for fluid;
Wherein, fluid perfusion passage is communicated with by fill orifice with the aperture on each electrode, is electrode sequence number and larger the closer to this catheter tip n if the diameter of the fill orifice corresponding to each electrode is d (n), n, then d (n) increases with n and increases.
2. electrode radio-frequency ablation catheter as claimed in claim 1, it is characterized in that, the adjustable extent of the diameter of this circular segment place circumference is between 10-40mm.
3. electrode radio-frequency ablation catheter as claimed in claim 1, is characterized in that, electrode sum is between 4-10.
4. electrode radio-frequency ablation catheter as claimed in claim 1, is characterized in that, the little hole number on each electrode is 5-100.
5. electrode radio-frequency ablation catheter as claimed in claim 1, it is characterized in that, each hole diameter on each electrode is between 0.03-0.3mm.
6. electrode radio-frequency ablation catheter as claimed in claim 1, is characterized in that, the quantity of the fill orifice corresponding to each electrode is 1-3.
7. electrode radio-frequency ablation catheter as claimed in claim 1, it is characterized in that, the diameter of each fill orifice is between 0.1-0.6mm.
8. electrode radio-frequency ablation catheter as claimed in claim 1, it is characterized in that, a fill orifice answered by each electrode pair, and the diameter of each fill orifice is uniform increments with the increase of described electrode sequence number n.
9. electrode radio-frequency ablation catheter as claimed in claim 1, it is characterized in that, a fill orifice answered by each electrode pair, and the diameter d (n) of each fill orifice=A+Bn+Cn 2, wherein
A=A1-A2*N, A1 are between 1.07 ~ 1.09, and A2 is between 0.02 ~ 0.03;
B=B1-B2*N, B1 are between 0.08 ~ 0.10, and B2 is between 0.001 ~ 0.003;
C=C1*N+C2, C1 are between 0.0001 ~ 0.001, and C2 is between 0.0001 ~ 0.001;
N is the sum of electrode.
10. electrode radio-frequency ablation catheter as claimed in claim 1, it is characterized in that, 2 fill orifices answered by least part of electrode pair.
11. electrode radio-frequency ablation catheters as claimed in claim 10, is characterized in that, the electrode of corresponding 2 fill orifices is positioned at catheter tip.
12. 1 kinds of catheter ablation devices, comprise the electrode radio-frequency ablation catheter as described in any one of claim 1-11.
CN201410369680.4A 2014-07-30 2014-07-30 Catheter ablation device and its electrode radio-frequency ablation catheter Active CN105286986B (en)

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CN203493737U (en) * 2013-10-15 2014-03-26 上海微创电生理医疗科技有限公司 Medical treatment catheter and radiofrequency treatment system
CN203539434U (en) * 2013-04-12 2014-04-16 上海微创电生理医疗科技有限公司 Multi-electrode ablation catheter
CN204158487U (en) * 2014-07-30 2015-02-18 上海微创电生理医疗科技有限公司 Catheter ablation device and electrode radio-frequency ablation catheter thereof

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CN102274021A (en) * 2010-04-21 2011-12-14 韦伯斯特生物官能(以色列)有限公司 Dual-purpose lasso catheter with irrigation using circumferentially arranged ring bump electrodes
CN103142304A (en) * 2012-11-13 2013-06-12 陈绍良 Multistage synchronous pulmonary artery radiofrequency ablation catheter
CN203539434U (en) * 2013-04-12 2014-04-16 上海微创电生理医疗科技有限公司 Multi-electrode ablation catheter
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114259294A (en) * 2018-09-14 2022-04-01 杭州堃博生物科技有限公司 Radiofrequency ablation catheter, pulmonary radiofrequency ablation system and corresponding control method

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