CN105267663A - Preparation method of immersion tablet for treating rheumatism - Google Patents
Preparation method of immersion tablet for treating rheumatism Download PDFInfo
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- CN105267663A CN105267663A CN201510826915.2A CN201510826915A CN105267663A CN 105267663 A CN105267663 A CN 105267663A CN 201510826915 A CN201510826915 A CN 201510826915A CN 105267663 A CN105267663 A CN 105267663A
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Abstract
The invention discloses a preparation method of an immersion tablet for treating rheumatism. The method comprises the following steps: (1) weighing the following raw materials in parts by weight: 15-25 parts of mimosa pudica, 15-25 parts of herba taxilli, 15-25 parts of rhizoma cibotii, 3-6 parts of fourstamen stephania roots, 8-12 parts of rhizoma alismatis, 15-25 parts of poria cocos, 12-18 parts of rhizoma atractylodis, 4-6 parts of cortex phellodendri, 8-12 parts of lycopodium clavatum, 8-12 parts of panax notoginseng, 8-15 parts of angelica sinensis, 8-12 parts of radix polygonati officinalis, 8-12 parts of polygonatum kingianum, 8-12 parts of wolfberry, 8-12 parts of radix dipsaci, 8-12 parts of rhizoma drynariae, 8-12 parts of rhizoma atractylodis macrocephalae and 8-12 parts of divaricate saposhnikovia roots; (2) crushing the weighed raw materials and mixing and leaching with ethanol to obtain a leaching stock solution; and (3) purifying and diluting the leaching stock solution to obtain a leaching liquid, adsorbing the leaching liquid on an absorbent carrier, and sealing to obtain the immersion tablet.
Description
Technical field
The present invention relates to tcm field, particularly relate to a kind of immersion sheet for the treatment of rheumatism and preparation method thereof, can by skin absorb the drug effective ingredient treatment rheumatism.
Background technology
Rheumatism is one group, and to invade joint, skeleton, muscle, blood vessel and relevant soft tissue or connective tissue be the disease led, and wherein majority is autoimmune disease.Morbidity is much more hidden and slow, and the course of disease is longer, and mostly has genetic predisposition.Doctor trained in Western medicine all acquires a certain degree of difficulty to rheumatismal Treatment and diagnosis; How different autoantibodys can be checked out in blood, may be relevant from different HLA hypotype; To nonsteroidal anti-inflammatory agent (NSAID), glucocorticoid and immunosuppressant have good short-term or the reaction of long-term palliative.Rheumatism has arthropathy and symptom mostly, can up to 70-80%, and about 50% only has pain, heavy then red, swollen, heat, pain and comprehensive inflammation performance such as function is impaired.
At present, the antirheumatic etc. that western medical treatment rheumatism generally adopts nonsteroidal anti-inflammatory agent, adrenocortical hormone or improves the state of an illness carries out Drug therapy, or according to circumstances takes operative treatment, and side effect is all larger.The Chinese medicine composition effectively can treating rheumatism is lacked in prior art.At present, the immersion sheet of rheumatism therapy is not also applied to.
Summary of the invention
An object of the present invention is to solve at least the problems referred to above and/or defect, and the advantage will illustrated at least is below provided.
Another object of the present invention is to provide a kind of preparation method for the treatment of the immersion sheet of rheumatism, effective ingredient can be made fully to be absorbed through skin pore, effectively treat rheumatism.
Other objects with some for achieving the above object, the present invention adopts following technical scheme:
Treat a preparation method for the immersion sheet of rheumatism, comprise the following steps:
Step one, take the crude drug of following weight portion: deer break grass 15-25, Herba Taxilli 15-25, Rhizoma Cibotii 15-25, Radix Stephaniae Tetrandrae 3-6, Rhizoma Alismatis 8-12, Poria 15-25, Rhizoma Atractylodis 12-18, Cortex Phellodendri 4-6, Herba Lycopodii 8-12, Radix Notoginseng 8-12, Radix Angelicae Sinensis 8-15, Rhizoma Polygonati Odorati 8-12, Rhizoma Polygonati 8-12, Fructus Lycii 8-12, Radix Dipsaci 8-12, Rhizoma Drynariae 8-12, Rhizoma Atractylodis Macrocephalae 8-12 and Radix Saposhnikoviae 8-12;
Step 2, by taken crude drug pulverize after with ethanol mixing lixiviate, obtain lixiviate stock solution;
Step 3, by lixiviate stock solution purification dilute, obtain lixiviating solution, lixiviating solution be adsorbed onto on water absorption carrier, sealing, obtain described immersion sheet.
Preferably, in the preparation method of the immersion sheet of described treatment rheumatism, crude drug described in step one comprises the component of following weight portion:
Deer break grass 20, Herba Taxilli 20, Rhizoma Cibotii 20, Radix Stephaniae Tetrandrae 5, Rhizoma Alismatis 10, Poria 20, Rhizoma Atractylodis 15, Cortex Phellodendri 5, Herba Lycopodii 10, Radix Notoginseng 10, Radix Angelicae Sinensis 12, Rhizoma Polygonati Odorati 10, Rhizoma Polygonati 10, Fructus Lycii 10, Radix Dipsaci 10, Rhizoma Drynariae 10, the Rhizoma Atractylodis Macrocephalae 10 and Radix Saposhnikoviae 10.
Preferably, in the preparation method of the immersion sheet of described treatment rheumatism, in step 2, concentration of alcohol used is 70-80%; Ethanol consumption is 5-20 times of crude drug volume.
Preferably, in the preparation method of the immersion sheet of described treatment rheumatism, in step 2, crude drug is crushed to 50-120 order.
Preferably, in the preparation method of the immersion sheet of described treatment rheumatism, the carrier of water absorption described in step 3 is cotton, fluffy cotton or water-absorbing resins.
The present invention at least comprises following beneficial effect: first, the present invention utilizes the traditional Chinese medical science five elements and dialectical theory, think that the cause of disease of rheumatism is: rheumatism is the pathogen of six climate exopathogens, invades in fur, then invades in blood vessels, then invade and gather in meat, to such an extent as to disease passes in muscles and bones, can not heal for a long time, in the course of time, health deficiency of vital QI, becomes chronic disease.Liver storing blood, irritability rage, vim and vigour are seethed, now wind-engaging, the straight impairing the liver of wind.Improper diet, famine is full to be pondered over too far frequently, and spleen channel is weak, and insufficiency of the spleen then stomach is weak, and diet is wet, and extraneous damp, easily invades, wind and wet heterozygosis, then impairing the liver spleen, and then liver of a specified duration is insufficiency of the spleen weak, and weakness then rheumatism can not be removed, to become rheumatism.The present invention is by nourshing blood and promoting blood circulation with hepatoprotective, and strengthening the spleen and nourishing the stomach, disperse water wets, and diseases prevention is deep, supports kidney bone and muscle strengthening, rheumatism is dispelled.
Secondly, the present invention is by being adsorbed on water absorption carrier by medicinal liquid, obtain being full of the immersion sheet having ingredient, can patient illness part be attached to, be absorbed the drug effective ingredient by pore, have no side effect, easy to use, and be conducive to the quick absorption of medicine, shorten action time, and improve therapeutic effect.
Part is embodied by explanation below by other advantage of the present invention, target and feature, part also will by research and practice of the present invention by those skilled in the art is understood.
Detailed description of the invention
Below the present invention is elaborated, can implement according to this after consulting this description to make those of ordinary skill in the art.
Treat a preparation method for the immersion sheet of rheumatism, comprise the following steps: step one, take the crude drug of following weight portion: deer break grass 15-25, Herba Taxilli 15-25, Rhizoma Cibotii 15-25, Radix Stephaniae Tetrandrae 3-6, Rhizoma Alismatis 8-12, Poria 15-25, Rhizoma Atractylodis 12-18, Cortex Phellodendri 4-6, Herba Lycopodii 8-12, Radix Notoginseng 8-12, Radix Angelicae Sinensis 8-15, Rhizoma Polygonati Odorati 8-12, Rhizoma Polygonati 8-12, Fructus Lycii 8-12, Radix Dipsaci 8-12, Rhizoma Drynariae 8-12, Rhizoma Atractylodis Macrocephalae 8-12 and Radix Saposhnikoviae 8-12; Step 2, by taken crude drug pulverize after with ethanol mixing lixiviate, obtain lixiviate stock solution; Step 3, by lixiviate stock solution purification dilute, obtain lixiviating solution, lixiviating solution be adsorbed onto on water absorption carrier, sealing, obtain described immersion sheet.
The present invention utilizes the traditional Chinese medical science five elements and dialectical theory, thinks that the cause of disease of rheumatism is: rheumatism is the pathogen of six climate exopathogens, invades in fur, then invades in blood vessels, then invade and gather in meat, to such an extent as to disease passes in muscles and bones, can not heal for a long time, in the course of time, health deficiency of vital QI, becomes chronic disease.Liver storing blood, irritability rage, vim and vigour are seethed, now wind-engaging, the straight impairing the liver of wind.Improper diet, famine is full to be pondered over too far frequently, and spleen channel is weak, and insufficiency of the spleen then stomach is weak, and diet is wet, and extraneous damp, easily invades, wind and wet heterozygosis, then impairing the liver spleen, and then liver of a specified duration is insufficiency of the spleen weak, and weakness then rheumatism can not be removed, to become rheumatism.The present invention is by nourshing blood and promoting blood circulation with hepatoprotective, and strengthening the spleen and nourishing the stomach, disperse water wets, and diseases prevention is deep, supports kidney bone and muscle strengthening, rheumatism is dispelled.
Concrete pharmacology is: deer break grass, and its taste is micro-salty, the kidney invigorating bone strengthening, treats rheumatism lingering arthralgia.Herba Taxilli, Rhizoma Cibotii, Radix Dipsaci, Rhizoma Drynariae the kidney invigorating bone strengthening, in diseases prevention passes, and treat rheumatism.Herba Lycopodii relaxing muscles and tendons.Radix Angelicae Sinensis, Rhizoma Polygonati Odorati, Rhizoma Polygonati, Fructus Lycii, Radix Notoginseng nourish blood hepatoprotective.Rhizoma Atractylodis wet dissipation is held concurrently dampness.The Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri strengthening the spleen and nourishing the stomach dampness.Radix Stephaniae Tetrandrae, Rhizoma Alismatis, Poria eliminating dampness by diuresis.Fang-feng powder wind.
The present invention is by being adsorbed on water absorption carrier by medicinal liquid, obtain being full of the immersion sheet having ingredient, patient illness part can be attached to, to be absorbed the drug effective ingredient by pore, have no side effect, easy to use, and be conducive to the quick absorption of medicine, shorten action time, and improve therapeutic effect.
In the preparation method of the immersion sheet of described treatment rheumatism, crude drug described in step one comprises the component of following weight portion: deer break grass 20, Herba Taxilli 20, Rhizoma Cibotii 20, Radix Stephaniae Tetrandrae 5, Rhizoma Alismatis 10, Poria 20, Rhizoma Atractylodis 15, Cortex Phellodendri 5, Herba Lycopodii 10, Radix Notoginseng 10, Radix Angelicae Sinensis 12, Rhizoma Polygonati Odorati 10, Rhizoma Polygonati 10, Fructus Lycii 10, Radix Dipsaci 10, Rhizoma Drynariae 10, the Rhizoma Atractylodis Macrocephalae 10 and Radix Saposhnikoviae 10.
In the preparation method of the immersion sheet of described treatment rheumatism, in step 2, concentration of alcohol used is 70-80%; Ethanol consumption is 5-20 times of crude drug volume.In step 2, crude drug is crushed to 50-120 order.The carrier of water absorption described in step 3 is cotton, fluffy cotton or water-absorbing resins.
During use, described immersion sheet is attached at affected part, and to its transferring heat, immersion sheet is heated, reach the effect of hot compress, to promote that effective ingredient absorbs, effective ingredient output speed can be accelerated on the one hand by being heated, heated skin pore is opened on the other hand, and local blood circulation is accelerated, and is conducive to the quick absorption of drug effect, shorten action time, and improve therapeutic effect.Each hot compress time is 60-90 minute, every hot compress in 3-5 hour once, and treatment more than 20 days Be very effective continuously.
Although embodiment of the present invention are open as above, but it is not restricted to listed in description and embodiment utilization, it can be applied to various applicable the field of the invention completely, for those skilled in the art, can easily realize other amendment, therefore do not deviating under the general concept that claim and equivalency range limit, the present invention is not limited to specific details.
Claims (5)
1. treat a preparation method for the immersion sheet of rheumatism, it is characterized in that, comprise the following steps:
Step one, take the crude drug of following weight portion: deer break grass 15-25, Herba Taxilli 15-25, Rhizoma Cibotii 15-25, Radix Stephaniae Tetrandrae 3-6, Rhizoma Alismatis 8-12, Poria 15-25, Rhizoma Atractylodis 12-18, Cortex Phellodendri 4-6, Herba Lycopodii 8-12, Radix Notoginseng 8-12, Radix Angelicae Sinensis 8-15, Rhizoma Polygonati Odorati 8-12, Rhizoma Polygonati 8-12, Fructus Lycii 8-12, Radix Dipsaci 8-12, Rhizoma Drynariae 8-12, Rhizoma Atractylodis Macrocephalae 8-12 and Radix Saposhnikoviae 8-12;
Step 2, by taken crude drug pulverize after with ethanol mixing lixiviate, obtain lixiviate stock solution;
Step 3, by lixiviate stock solution purification dilute, obtain lixiviating solution, lixiviating solution be adsorbed onto on water absorption carrier, sealing, obtain described immersion sheet.
2. the preparation method of the immersion sheet for the treatment of rheumatism as claimed in claim 1, it is characterized in that, crude drug described in step one comprises the component of following weight portion:
Deer break grass 20, Herba Taxilli 20, Rhizoma Cibotii 20, Radix Stephaniae Tetrandrae 5, Rhizoma Alismatis 10, Poria 20, Rhizoma Atractylodis 15, Cortex Phellodendri 5, Herba Lycopodii 10, Radix Notoginseng 10, Radix Angelicae Sinensis 12, Rhizoma Polygonati Odorati 10, Rhizoma Polygonati 10, Fructus Lycii 10, Radix Dipsaci 10, Rhizoma Drynariae 10, the Rhizoma Atractylodis Macrocephalae 10 and Radix Saposhnikoviae 10.
3. the preparation method of the immersion sheet for the treatment of rheumatism as claimed in claim 1, it is characterized in that, in step 2, concentration of alcohol used is 70-80%; Ethanol consumption is 5-20 times of crude drug volume.
4. the preparation method of the immersion sheet for the treatment of rheumatism as claimed in claim 1, is characterized in that, in step 2, crude drug is crushed to 50-120 order.
5. the preparation method of the immersion sheet for the treatment of rheumatism as claimed in claim 1, it is characterized in that, the carrier of water absorption described in step 3 is cotton, fluffy cotton or water-absorbing resins.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510826915.2A CN105267663A (en) | 2015-11-25 | 2015-11-25 | Preparation method of immersion tablet for treating rheumatism |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510826915.2A CN105267663A (en) | 2015-11-25 | 2015-11-25 | Preparation method of immersion tablet for treating rheumatism |
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| CN105267663A true CN105267663A (en) | 2016-01-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510826915.2A Pending CN105267663A (en) | 2015-11-25 | 2015-11-25 | Preparation method of immersion tablet for treating rheumatism |
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| CN (1) | CN105267663A (en) |
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2015
- 2015-11-25 CN CN201510826915.2A patent/CN105267663A/en active Pending
Non-Patent Citations (3)
| Title |
|---|
| 孙世发主编: "《中华医方内科篇肾系病》", 31 March 2015, 北京科学技术文献出版社 * |
| 陈斌主编: "《过敏性皮肤病用药与食疗》", 31 October 2014, 北京金盾出版社 * |
| 陈永韶: ""芪归汤治疗痹证125例"", 《吉林中医药》 * |
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Application publication date: 20160127 |
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