CN105266957A - Artificial retina stimulating electrode and manufacturing method therefor - Google Patents
Artificial retina stimulating electrode and manufacturing method therefor Download PDFInfo
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- CN105266957A CN105266957A CN201510059748.3A CN201510059748A CN105266957A CN 105266957 A CN105266957 A CN 105266957A CN 201510059748 A CN201510059748 A CN 201510059748A CN 105266957 A CN105266957 A CN 105266957A
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Abstract
The invention discloses an artificial retina stimulating electrode and a manufacturing method therefor. The simulating electrode comprises an electrode head portion, a thin portion, an electrode body portion and a connection portion. The electrode head portion comprises an elliptical flexible substrate, a first fixing nail, a second fixing nail, a contact electrode and a wire electrode connected to the contact electrode, and the electrode wire penetrates the thin portion, the electrode body portion and the connection portion. The thin portion is connected to the electrode head portion. The electrode body portion is connected to the thin portion. The connection portion is connected to the electrode body portion via a circular bead, and comprises a conical portion, a triangular portion a loop electrode and a loop wire electrode connected to the loop electrode. The artificial retina stimulating electrode can make contact with a macula lutea zone of the retina, the effect of simulation is good, the size of the artificial retina stimulating electrode is small, so the artificial retina stimulating electrode can be implanted in the eye through a small incision, so the artificial retina stimulating electrode is convenient to implant and fix with a small incision.
Description
Technical field
The invention belongs to medical instruments field, particularly a kind of artificial retina stimulating electrode and preparation method thereof.
Background technology
Artificial retina is implanted into electrode, figure phase processor, microcam and transporter by eyeball and forms.Convert the signal of telecommunication after figure is recorded by microcam to and be resent to figure phase processor by signal amplification, filtration, and be sent to receptor by conveyer, the electric pulse produced delivers to corresponding stimulating electrode contact, thus stimulate the neurocyte looking retina inner surface lower floor, make optic nerve produce excited and import figure phase information into brain, form vision.In whole Human Visual System, artificial retina stimulating electrode is very important ingredient.
The size of artificial retina stimulating electrode, contact electrode arrayed and be fixedly the important technical problem existed at present.The object of implantable artificial retinal stimulating electrodes allows blind person see image, and make image clear as much as possible.Simultaneously because eyes are very tender and lovely organs, this just requires that each contact electrode is little as much as possible, the electric stimulation pulse scope that it spreads out of is concentrated as much as possible, and the neurocyte number be upset in unit are is like this just as far as possible many, and the information transmitted will be abundanter.General artificial prosthesis fixing is all the mode by sewing up, but this mode is not suitable for the fixing of artificial retina stimulating electrode, and large to ocular trauma, risk is high.
Summary of the invention
The technical problem to be solved in the present invention is to provide one and can contacts with macula retinae district better, effect of stimulation is better, volume is little can implant ophthalmic by minimal incision *, wound is little, the convenient artificial retina stimulating electrode implanted and fix, and preparation method thereof.
To achieve these goals, technical scheme of the present invention is as follows: a kind of artificial retina stimulating electrode, comprises electrode tip part, FF, electrode body part and coupling part, wherein,
Described electrode head divides the wire electrode comprising oval flexible substrates, the first staple, the second staple, contact electrode and be connected with contact electrode, described wire electrode runs through described FF, described electrode body part and described coupling part, and finally exposes described coupling part;
Described FF is cylindrical, divides be connected with described electrode head; Described electrode body part is cylindrical, and diameter is at most 2 times of described FF diameter, and described electrode body part is connected with described FF; Described coupling part is connected by fillet with described electrode body part, the loop electrode silk comprising tapered portion, triangular part, loop electrode and be connected with loop electrode.
Alternatively, described contact electrode is hat, embeds in described flexible substrates, and exposed area is 0.1-0.3mm
2, described wire electrode is the gold silk or the platinumiridio silk that have insulating outer layer.
Alternatively, described electrode tip part is long is 7-10mm, and wide is 5-6mm; 0.4-1mm is spaced apart, in rectangular arrangement between described contact electrode.
Alternatively, described electrode tip part also comprise be arranged on described contact electrode another side dorsal fin and dorsal fin on locating hole.
Alternatively, described electrode body part also comprises the fixing hole on fixing ear and fixing ear, and described fixing ear is parallel-laid into arranging 4-6 couple.
Alternatively, described FF is long is 18-25mm, and described electrode body part is long is 100-160mm.
Based on above-mentioned purpose, present invention also offers a kind of manufacture method of artificial retina stimulating electrode, comprise the following steps:
After carrying out punching press and cleaning to contact electrode, by wire electrode and contact electrode by being weldingly connected;
At long 7-10mm, inject silica gel in the electrode tip mould of the ellipse of wide 5-6mm, before silica gel does not solidify completely, several contact electrode of welding with wire electrode are pressed and is fixed on silica gel, in the arrangement of rectangular interval 0.4-1mm distance, ensure the some same directions of wire electrode simultaneously;
After the silica gel injected until previous step solidifies completely, namely contact electrode fixes, then in electrode tip mould, putting silica gel to the single contact electrode of hat, to be exposed to silica gel outer area be 0.1-0.3mm
2, form electrode tip part;
After some wire electrode reason line bunchys, turn to helical form, put into the columned mould 1 of slice from the electrode tow near electrode tip part, note silica gel wraps up wire electrode after fixing completely, forms FF;
It is the mould 1 columned mould 2 of slice of 2 times at the most that electrode tow after FF is put into diameter, and note silica gel wraps up wire electrode after fixing completely, forms electrode body part;
By welded loop electrode silk the electrode tow of loop electrode ring set after electrode body part outside, loop electrode silk is identical with electrode tow direction, put into and comprise taper, leg-of-mutton mould 3, note silica gel wraps up wire electrode and loop electrode silk after fixing completely, loop electrode is exposed to outside silica gel, forms coupling part.
Alternatively, described mould 2 comprises 4-6 to the ear structure be parallel-laid into arranging.
Alternatively, described mould 1 is long is 18-25mm, and described mould 2 is long is 100-160mm.
Beneficial effect of the present invention is: the substrate of artificial retina stimulating electrode is flexible substrates, can fit with the radian of eyeball, can contact with macula retinae district better, effect of stimulation is better, volume is little can implant ophthalmic by minimal incision *, wound is little, adopts the convenient implantation of staple with fixing; The manufacture method of artificial retina stimulating electrode is easy and simple to handle, and technological requirement is uncomplicated, and cost is low.
Accompanying drawing explanation
Fig. 1 is the structural representation of the artificial retinal stimulating electrodes of the present invention;
Fig. 2 is the present invention's artificial retinal stimulating electrodes electrode tip magnified partial view;
Fig. 3 is the present invention's artificial retinal stimulating electrodes electrode tip part contact electrode face enlarged drawing;
Fig. 4 is the manufacture method flow chart of steps of zoopery acoustic nerve stimulating electrode of the present invention;
Detailed description of the invention
Below in conjunction with accompanying drawing, the preferred embodiments of the present invention are described in detail.
See Fig. 1-Fig. 3, a kind of artificial retina stimulating electrode, comprises electrode tip part 1, FF 2, electrode body part 3 and coupling part 16, wherein,
The wire electrode 15 that described electrode tip part 1 comprises oval flexible substrates 114, first staple 4, second staple 8, contact electrode 7 and is connected with contact electrode 7, described wire electrode 15 runs through described FF 2, described electrode body part 3 and described coupling part 16, and finally exposes described coupling part 16; Electrode tip part 1 also comprises the first fixing hole 111 and the second fixing hole 112, first staple 4 inserts in the first fixing hole 111, and the second staple 8 inserts in the second fixing hole 112;
Described FF 2 is cylindrical, is connected with described electrode tip part 1, and the part be connected is for reinforcing fillet 113; Described electrode body part 3 is cylindrical, and diameter is at most 2 times of described FF 2 diameter, and described electrode body part 3 is connected with described FF 2; Described coupling part 16 is connected by fillet 11 with described electrode body part 3, the loop electrode silk comprising tapered portion 13, triangular part 14, loop electrode 12 and be connected with loop electrode 12.
Further, described contact electrode 7 is hat, and embed in described flexible substrates 114, exposed area is 0.1-0.3mm
2, described wire electrode 15 is for having gold silk or the platinumiridio silk of insulating outer layer.
Further, described electrode tip part 1 is long is 7-10mm, and wide is 5-6mm; Be spaced apart 0.4-1mm between described contact electrode 7, in rectangular arrangement, can arrange 16-256 contact electrode 7 in a specific embodiment, the number of contact electrode 7 is more, stimulates the effect of optic nerve better.
Further, described electrode tip part 1 also comprise be arranged on described contact electrode 7 another side dorsal fin 5 and dorsal fin 5 on locating hole 6, operate with implantation tweezer securely for more stable in implantation process.
Further, described electrode body part 3 also comprises the fixing hole 10 on fixing ear 9 and fixing ear 9, and described fixing ear 9 is parallel-laid into arranging 4-6 couple, for electrode body part 3 is sewn on scalp region, is fixed with effect better to artificial retina stimulating electrode.
Further, described FF 2 is long is 18-25mm, and described electrode body part 3 is long is 100-160mm.
Corresponding with above-mentioned zoopery acoustic nerve stimulating electrode, further embodiment of this invention provides the manufacture method of artificial retina stimulating electrode, and its flow chart, see Fig. 4, comprises the following steps:
S101, after carrying out punching press and cleaning to contact electrode, by wire electrode and contact electrode by being weldingly connected;
S102, at long 7-10mm, silica gel is injected in the electrode tip mould of the ellipse of wide 5-6mm, before silica gel does not solidify completely, several contact electrode of welding with wire electrode being pressed is fixed on silica gel, in the equidistant arrangement of rectangular interval 0.4-1mm, ensure the some same directions of wire electrode simultaneously;
S103, after the silica gel injected until previous step solidifies completely, namely contact electrode fixes, then in electrode tip mould, putting silica gel to the single contact electrode of hat, to be exposed to silica gel outer area be 0.1-0.3mm
2, form electrode tip part;
S104, after some wire electrode reason line bunchys, turn to helical form, put into the columned mould 1 of slice from the electrode tow near electrode tip part, note silica gel wraps up wire electrode after fixing completely, forms FF;
S105, it is the mould 1 columned mould 2 of slice of 2 times at the most that the electrode tow after FF is put into diameter, and note silica gel wraps up wire electrode after fixing completely, forms electrode body part;
S106, by welded loop electrode silk the electrode tow of loop electrode ring set after electrode body part outside, loop electrode silk is identical with electrode tow direction, put into and comprise taper, leg-of-mutton mould 3, note silica gel wraps up wire electrode and loop electrode silk after fixing completely, loop electrode is exposed to outside silica gel, forms coupling part.
Further, described mould 2 comprises 4-6 to the ear structure be parallel-laid into arranging.
Further, described mould 1 is long is 18-25mm, and described mould 2 is long is 100-160mm.
What finally illustrate is, above preferred embodiment is only in order to illustrate technical scheme of the present invention and unrestricted, although by above preferred embodiment to invention has been detailed description, but those skilled in the art are to be understood that, various change can be made to it in the form and details, and not depart from claims of the present invention limited range.
Claims (9)
1. an artificial retina stimulating electrode, is characterized in that, comprises electrode tip part, FF, electrode body part and coupling part, wherein,
Described electrode head divides the wire electrode comprising oval flexible substrates, the first staple, the second staple, contact electrode and be connected with contact electrode, described wire electrode runs through described FF, described electrode body part and described coupling part, and finally exposes described coupling part;
Described FF is cylindrical, divides be connected with described electrode head; Described electrode body part is cylindrical, and diameter is at most 2 times of described FF diameter, and described electrode body part is connected with described FF; Described coupling part is connected by fillet with described electrode body part, the loop electrode silk comprising tapered portion, triangular part, loop electrode and be connected with loop electrode.
2. artificial retina stimulating electrode according to claim 1, is characterized in that, described contact electrode is hat, embeds in described flexible substrates, and exposed area is 0.1-0.3mm
2, described wire electrode is the gold silk or the platinumiridio silk that have insulating outer layer.
3. artificial retina stimulating electrode according to claim 1, is characterized in that, described electrode tip part is long is 7-10mm, and wide is 5-6mm; 0.4-1mm is spaced apart, in rectangular arrangement between described contact electrode.
4. artificial retina stimulating electrode according to claim 1, is characterized in that, described electrode tip part also comprise be arranged on described contact electrode another side dorsal fin and dorsal fin on locating hole.
5. the artificial retina stimulating electrode according to claim, is characterized in that, described electrode body part also comprises the fixing hole on fixing ear and fixing ear, and described fixing ear is parallel-laid into arranging 4-6 couple.
6. according to the artificial retina stimulating electrode one of claim 1-5 Suo Shu, it is characterized in that, described FF is long is 18-25mm, and described electrode body part is long is 100-160mm.
7. a manufacture method for artificial retina stimulating electrode, is characterized in that, comprises the following steps:
After carrying out punching press and cleaning to contact electrode, by wire electrode and contact electrode by being weldingly connected;
At long 7-10mm, inject silica gel in the electrode tip mould of the ellipse of wide 5-6mm, before silica gel does not solidify completely, several contact electrode of welding with wire electrode are pressed and is fixed on silica gel, in the arrangement of rectangular interval 0.4-1mm distance, ensure the some same directions of wire electrode simultaneously;
After the silica gel injected until previous step solidifies completely, namely contact electrode fixes, then in electrode tip mould, putting silica gel to the single contact electrode of hat, to be exposed to silica gel outer area be 0.1-0.3mm
2, form electrode tip part;
After some wire electrode reason line bunchys, turn to helical form, put into the columned mould 1 of slice from the electrode tow near electrode tip part, note silica gel wraps up wire electrode after fixing completely, forms FF;
It is the mould 1 columned mould 2 of slice of 2 times at the most that electrode tow after FF is put into diameter, and note silica gel wraps up wire electrode after fixing completely, forms electrode body part;
By welded loop electrode silk the electrode tow of loop electrode ring set after electrode body part outside, loop electrode silk is identical with electrode tow direction, put into and comprise taper, leg-of-mutton mould 3, note silica gel wraps up wire electrode and loop electrode silk after fixing completely, loop electrode is exposed to outside silica gel, forms coupling part.
8. the manufacture method of zoopery acoustic nerve stimulating electrode according to claim 7, is characterized in that, described mould 2 comprises 4-6 to the ear structure be parallel-laid into arranging.
9. the manufacture method of zoopery acoustic nerve stimulating electrode according to claim 7, is characterized in that, described mould 1 is long is 18-25mm, and described mould 2 is long is 100-160mm.
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105536136A (en) * | 2016-02-03 | 2016-05-04 | 浙江诺尔康神经电子科技股份有限公司 | Manufacturing method for auditory brainstem stimulation electrode |
CN105561470A (en) * | 2016-02-03 | 2016-05-11 | 浙江诺尔康神经电子科技股份有限公司 | Auditory brainstem stimulation electrode |
CN106334258A (en) * | 2016-08-22 | 2017-01-18 | 深圳硅基仿生科技有限公司 | Stimulating electrode structure of artificial retina and artificial retina |
CN109675189A (en) * | 2018-12-12 | 2019-04-26 | 深圳先进技术研究院 | Neural stimulation electrodes, implant, silica gel packaging method and silica gel packaging equipment |
WO2022126612A1 (en) * | 2020-12-18 | 2022-06-23 | 深圳先进技术研究院 | Fixing device |
CN114917470A (en) * | 2022-06-23 | 2022-08-19 | 浙江大学 | Retina stimulation electrode with fundus pattern information and manufacturing method thereof |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5935155A (en) * | 1998-03-13 | 1999-08-10 | John Hopkins University, School Of Medicine | Visual prosthesis and method of using same |
CN101396583A (en) * | 2008-10-30 | 2009-04-01 | 上海交通大学 | Vision prosthesis device based on optical-disc micro-electrode array |
JP4412970B2 (en) * | 2002-12-02 | 2010-02-10 | 株式会社ニデック | Method for producing biological tissue stimulation electrode |
US8175714B2 (en) * | 2001-02-13 | 2012-05-08 | Second Sight Medical Products, Inc. | Implantable retinal electrode array configuration for minimal retinal damage and method of reducing retinal stress |
CN103690300A (en) * | 2013-12-19 | 2014-04-02 | 中国医学科学院生物医学工程研究所 | Retinal prosthesis with spherical arc substrate |
CN104013491A (en) * | 2014-05-23 | 2014-09-03 | 浙江诺尔康神经电子科技股份有限公司 | Foldable minimally-invasive artificial retina microelectrode array |
CN104147695A (en) * | 2014-08-19 | 2014-11-19 | 浙江诺尔康神经电子科技股份有限公司 | Animal experiment auditory nerve stimulation electrode and device and manufacture method thereof |
CN204521181U (en) * | 2015-02-05 | 2015-08-05 | 浙江诺尔康神经电子科技股份有限公司 | Artificial retina stimulating electrode |
-
2015
- 2015-02-05 CN CN201510059748.3A patent/CN105266957A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5935155A (en) * | 1998-03-13 | 1999-08-10 | John Hopkins University, School Of Medicine | Visual prosthesis and method of using same |
US8175714B2 (en) * | 2001-02-13 | 2012-05-08 | Second Sight Medical Products, Inc. | Implantable retinal electrode array configuration for minimal retinal damage and method of reducing retinal stress |
JP4412970B2 (en) * | 2002-12-02 | 2010-02-10 | 株式会社ニデック | Method for producing biological tissue stimulation electrode |
CN101396583A (en) * | 2008-10-30 | 2009-04-01 | 上海交通大学 | Vision prosthesis device based on optical-disc micro-electrode array |
CN103690300A (en) * | 2013-12-19 | 2014-04-02 | 中国医学科学院生物医学工程研究所 | Retinal prosthesis with spherical arc substrate |
CN104013491A (en) * | 2014-05-23 | 2014-09-03 | 浙江诺尔康神经电子科技股份有限公司 | Foldable minimally-invasive artificial retina microelectrode array |
CN104147695A (en) * | 2014-08-19 | 2014-11-19 | 浙江诺尔康神经电子科技股份有限公司 | Animal experiment auditory nerve stimulation electrode and device and manufacture method thereof |
CN204521181U (en) * | 2015-02-05 | 2015-08-05 | 浙江诺尔康神经电子科技股份有限公司 | Artificial retina stimulating electrode |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105536136A (en) * | 2016-02-03 | 2016-05-04 | 浙江诺尔康神经电子科技股份有限公司 | Manufacturing method for auditory brainstem stimulation electrode |
CN105561470A (en) * | 2016-02-03 | 2016-05-11 | 浙江诺尔康神经电子科技股份有限公司 | Auditory brainstem stimulation electrode |
CN106334258A (en) * | 2016-08-22 | 2017-01-18 | 深圳硅基仿生科技有限公司 | Stimulating electrode structure of artificial retina and artificial retina |
CN106334258B (en) * | 2016-08-22 | 2019-01-18 | 深圳硅基仿生科技有限公司 | The stimulating electrode structure and artificial retina of artificial retina |
CN109364369A (en) * | 2016-08-22 | 2019-02-22 | 深圳硅基仿生科技有限公司 | The stimulating electrode structure and artificial retina of artificial retina |
CN109675189A (en) * | 2018-12-12 | 2019-04-26 | 深圳先进技术研究院 | Neural stimulation electrodes, implant, silica gel packaging method and silica gel packaging equipment |
WO2022126612A1 (en) * | 2020-12-18 | 2022-06-23 | 深圳先进技术研究院 | Fixing device |
CN114917470A (en) * | 2022-06-23 | 2022-08-19 | 浙江大学 | Retina stimulation electrode with fundus pattern information and manufacturing method thereof |
CN114917470B (en) * | 2022-06-23 | 2023-11-07 | 浙江大学 | Retina stimulating electrode with fundus pattern information and manufacturing method thereof |
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Application publication date: 20160127 |