CN105250737A - Medicine for treating migraine - Google Patents
Medicine for treating migraine Download PDFInfo
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- CN105250737A CN105250737A CN201510774428.6A CN201510774428A CN105250737A CN 105250737 A CN105250737 A CN 105250737A CN 201510774428 A CN201510774428 A CN 201510774428A CN 105250737 A CN105250737 A CN 105250737A
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- 239000003814 drug Substances 0.000 title claims abstract description 36
- 208000019695 Migraine disease Diseases 0.000 title abstract description 10
- 206010027599 migraine Diseases 0.000 title abstract description 10
- 229940079593 drug Drugs 0.000 title description 2
- 210000000582 semen Anatomy 0.000 claims abstract description 15
- 239000000203 mixture Substances 0.000 claims description 18
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 14
- 239000009636 Huang Qi Substances 0.000 claims description 12
- 241000522620 Scorpio Species 0.000 claims description 6
- 239000009490 scorpio Substances 0.000 claims description 6
- 208000002193 Pain Diseases 0.000 abstract description 15
- 230000036407 pain Effects 0.000 abstract description 15
- 230000000694 effects Effects 0.000 abstract description 7
- 241001529821 Agastache Species 0.000 abstract 1
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 241000305491 Gastrodia elata Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 235000004347 Perilla Nutrition 0.000 abstract 1
- 244000124853 Perilla frutescens Species 0.000 abstract 1
- 244000274050 Platycodon grandiflorum Species 0.000 abstract 1
- 235000006753 Platycodon grandiflorum Nutrition 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 244000046146 Pueraria lobata Species 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 240000001341 Reynoutria japonica Species 0.000 abstract 1
- 235000018167 Reynoutria japonica Nutrition 0.000 abstract 1
- 241001162994 Rugosus Species 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 241000270666 Testudines Species 0.000 abstract 1
- 230000000037 effect on migraine Effects 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 206010019233 Headaches Diseases 0.000 description 15
- 231100000869 headache Toxicity 0.000 description 15
- 230000000306 recurrent effect Effects 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
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- 238000011084 recovery Methods 0.000 description 3
- 206010033474 Pain of skin Diseases 0.000 description 2
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- 230000003247 decreasing effect Effects 0.000 description 2
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- 231100000957 no side effect Toxicity 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 244000257039 Duranta repens Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses medicine for treating migraine. The medicine is prepared from gastrodia elata, prepared fleece flower roots, ligusticum wallichii, angelica sinensis, scutellaria baicalensis, notopterygium roots, roots of kudzu vine, platycodon grandiflorum, agastache rugosus, poria cocos, radix angelicae, purple perilla, turtle shells, semen cassia, liquorice, asarum, rhizoma atractylodis, saposhnicovia divaricata and radix ophiopogonis. All the ingredients are in compatibility, collateral dredging and pain relieving can be achieved, the obvious curative effect on migraine is achieved, no toxic or side effect exits, and relapse is obviously reduced.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to one and treat migrainous medicine.
Background technology
Migraine is clinical modal primary headache type; with the pulsatile headache of recurrent exerbation for principal character, generally continue 4 ~ 72 hours, can with Nausea and vomiting; light, Sound stimulat or daily routines all can increase the weight of headache, and quiet environment, rest can alleviate headache.Migraine is a kind of common chronic forms vascular illness, a lot of disease is in child and adolescence, the young and middle-aged phase reaches onset peak, women is common, men and women's Proportion of patients is about 1: 2 ~ 3, and in crowd, prevalence is 5% ~ 10%, often has genetic background, the cause of disease and pathogenesis are comparatively complicated, comprising: the factors such as the change of patient body internal hormone and food, medicine, weather, motion, sleep and surrounding, living habit, spirit, emotion.At present, clinical treatment migraine many employings Western medicine, and the medicine mostly being inhibition of pain is treated, and although the effect of compacting pain can be played, patient easily produces drug dependence, easy recurrent exerbation.Be adjusted to master within Chinese medicine is general, but have no the medicine for the treatment of migraine more targetedly at present.
Summary of the invention
Object of the present invention is exactly defect for above-mentioned existence and provides one to treat migrainous medicine.Each components compatibility of the present invention, can relieve the pain by dredging collateral, has significant curative effect, and has no side effect, obviously reduce recurrence to migraine.
It is comprise following composition that one of the present invention treats migrainous drug technique scheme: Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Scutellariae, Rhizoma Et Radix Notopterygii, Radix Puerariae, Radix Platycodonis, Herba Pogostemonis, Poria, the Radix Angelicae Dahuricae, Folium Perillae, Carapax Trionycis, Semen Cassiae, Radix Glycyrrhizae, Herba Asari, Rhizoma Atractylodis, Radix Saposhnikoviae, Radix Ophiopogonis.
Described one treats migrainous medicine, comprises following composition by weight: Rhizoma Gastrodiae 1-10 part, Radix Polygoni Multiflori Preparata 1-10 part, Rhizoma Chuanxiong 1-10 part, Radix Angelicae Sinensis 1-10 part, Radix Astragali 1-10 part, Rhizoma Et Radix Notopterygii 1-10 part, Radix Puerariae 1-10 part, Radix Platycodonis 1-10 part, Herba Pogostemonis 1-10 part, Poria 1-10 part, Radix Angelicae Dahuricae 1-10 part, Folium Perillae 1-10 part, Carapax Trionycis 1-10 part, Semen Cassiae 1-10 part, Radix Glycyrrhizae 1-10 part, Herba Asari 1-10 part, Rhizoma Atractylodis 1-10 part, Radix Saposhnikoviae 1-10 part, Radix Ophiopogonis 1-10 part.
Described one treats migrainous medicine, comprises following composition by weight: Rhizoma Gastrodiae 3-5 part, Radix Polygoni Multiflori Preparata 2-4 part, Rhizoma Chuanxiong 5-8 part, Radix Angelicae Sinensis 4-6 part, Radix Astragali 2-4 part, Rhizoma Et Radix Notopterygii 4-6 part, Radix Puerariae 6-10 part, Radix Platycodonis 4-6 part, Herba Pogostemonis 2-4 part, Poria 3-5 part, Radix Angelicae Dahuricae 4-6 part, Folium Perillae 3-5 part, Carapax Trionycis 3-5 part, Semen Cassiae 4-6 part, Radix Glycyrrhizae 4-8 part, Herba Asari 2-4 part, Rhizoma Atractylodis 2-4 part, Radix Saposhnikoviae 3-5 part, Radix Ophiopogonis 2-4 part.
Described one treats migrainous medicine, comprises following composition by weight: 4 parts, Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata 3 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 5 parts, the Radix Astragali 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Puerariae 8 parts, Radix Platycodonis 5 parts, Herba Pogostemonis 3 parts, 4 parts, Poria, the Radix Angelicae Dahuricae 5 parts, Folium Perillae 4 parts, Carapax Trionycis 4 parts, Semen Cassiae 5 parts, 6 parts, Radix Glycyrrhizae, Herba Asari 3 parts, Rhizoma Atractylodis 3 parts, Radix Saposhnikoviae 4 parts, Radix Ophiopogonis 3 parts.
Described one treats migrainous medicine, also comprises following composition by weight: Fructus Evodiae 3-6 part.
Described one treats migrainous medicine, comprises following composition by weight: 4 parts, Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata 3 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 5 parts, the Radix Astragali 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Puerariae 8 parts, Radix Platycodonis 5 parts, Herba Pogostemonis 3 parts, 4 parts, Poria, the Radix Angelicae Dahuricae 5 parts, Folium Perillae 4 parts, Carapax Trionycis 4 parts, Semen Cassiae 5 parts, 6 parts, Radix Glycyrrhizae, Herba Asari 3 parts, Rhizoma Atractylodis 3 parts, Radix Saposhnikoviae 4 parts, Radix Ophiopogonis 3 parts, Fructus Evodiae 5 parts.
Described one treats migrainous medicine, also comprises following composition by weight: Scorpio 4-6 part, Concha Ostreae 6-10 part.
Described one treats migrainous medicine, comprises following composition by weight: 4 parts, Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata 3 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 5 parts, the Radix Astragali 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Puerariae 8 parts, Radix Platycodonis 5 parts, Herba Pogostemonis 3 parts, 4 parts, Poria, the Radix Angelicae Dahuricae 5 parts, Folium Perillae 4 parts, Carapax Trionycis 4 parts, Semen Cassiae 5 parts, 6 parts, Radix Glycyrrhizae, Herba Asari 3 parts, Rhizoma Atractylodis 3 parts, Radix Saposhnikoviae 4 parts, Radix Ophiopogonis 3 parts, Fructus Evodiae 5 parts, Scorpio 4 parts, Concha Ostreae 8 parts.
One of the present invention treats migrainous medicine beneficial effect: each components compatibility of the present invention, can relieve the pain by dredging collateral, has significant curative effect, and has no side effect, obviously reduce recurrence to migraine.
Efficacy assessment standard is with reference to the guideline of clinical investigations evaluation curative effect of new Chinese medicine treatment headache.Pain intensity was with reference to International Headache association criterion in 1998: I grade: not bitterly; II grade: mild pain, but do not affect activity; III grade: moderate pain, but do not stop action; IV grade: severe pain, stiff.Clinical recovery: headache and simultaneous phenomenon disappear; Effective: pain degree alleviates 2 grades, and simultaneous phenomenon alleviates, or attack times, or durante dolors reduces more than 2/3; Effective: pain intensity alleviates 1 grade or outbreak extends interval time, or headache decreased duration is less than 2/3; Invalid: pain degree alleviates less than 1 grade, or headache decreased duration is less than 1/3, or pain increases the weight of and duration extension.
Treat in 233 examples, clinical recovery 156 example, effective 55 examples, effective 17 examples, total effective rate 97.9%.
detailed description of the invention:
In order to understand the present invention better, describe technical scheme of the present invention in detail with instantiation below, but the present invention is not limited thereto.
Embodiment 1
Described one treats migrainous medicine, is made up of following composition by weight: 4 parts, Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata 3 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 5 parts, the Radix Astragali 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Puerariae 8 parts, Radix Platycodonis 5 parts, Herba Pogostemonis 3 parts, 4 parts, Poria, the Radix Angelicae Dahuricae 5 parts, Folium Perillae 4 parts, Carapax Trionycis 4 parts, Semen Cassiae 5 parts, 6 parts, Radix Glycyrrhizae, Herba Asari 3 parts, Rhizoma Atractylodis 3 parts, Radix Saposhnikoviae 4 parts, Radix Ophiopogonis 3 parts, Fructus Evodiae 5 parts, Scorpio 4 parts, Concha Ostreae 8 parts.
30-60g is a pair, and add water and be boiled into decoction, every day takes at twice.
It within 7th, is a course for the treatment of.
Journey so-and-so, female, 49 years old, life is tired causes head side recurrent exerbation pulsatile headache with being busy with one's work, and with the disease such as nauseating, phonophobia, perspiration, general malaise, Scalp tenderness, quiet environment, rest can be alleviated, every inspection no abnormality seen, informal dress pain relieving class Western medicine, only take effect at that time, namely drug withdrawal recurs.Be migraine after diagnosing, take a course for the treatment of of medicine of the present invention, headache, nausea disappear, after taking three courses for the treatment of, headache, feel sick, phonophobia, perspiration, general malaise, the symptom such as Scalp tenderness disappear completely, even if also without any Symptoms under tired state, continue to take a course for the treatment of and consolidate, within 2 years so far, have a surplus without recurrence.
Zhang, man, 65 years old, migraine recurrent exerbation more than ten years, nearly a year and a half outbreak was frequent, and each outbreak continues 1-2 days, has a dizzy spell, tending to vomit of feeling sick.Head CT checks without exception.Take two courses for the treatment of of medicine of the present invention, pain gesture alleviates, within continuing half a day.After serveing on four courses for the treatment of, recover.Continue to strengthen two courses for the treatment of, within 2 years so far, have a surplus and do not recur.
Embodiment 2
Described one treats migrainous medicine, is made up of following composition by weight: 5 parts, Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata 2 parts, Rhizoma Chuanxiong 8 parts, Radix Angelicae Sinensis 6 parts, the Radix Astragali 4 parts, Rhizoma Et Radix Notopterygii 4 parts, Radix Puerariae 10 parts, Radix Platycodonis 5 parts, Herba Pogostemonis 2 parts, 3 parts, Poria, the Radix Angelicae Dahuricae 6 parts, Folium Perillae 3 parts, Carapax Trionycis 5 parts, Semen Cassiae 6 parts, 5 parts, Radix Glycyrrhizae, Herba Asari 4 parts, Rhizoma Atractylodis 2 parts, Radix Saposhnikoviae 3 parts, Radix Ophiopogonis 4 parts, Fructus Evodiae 6 parts, Scorpio 6 parts, Concha Ostreae 6 parts.
30-60g is a pair, and add water and be boiled into decoction, every day takes at twice.
It within 7th, is a course for the treatment of.
Lee, female, 54 years old, right side recurrent exerbation pulsatile headache, left side headache once in a while, companion is dizzy, nose heave pressure sensitivity, fidgety, nervous, insomnia and dreamful sleep, takes Western medicine invalid, takes a course for the treatment of of medicine of the present invention, symptom alleviates, sleep is good, and after taking three courses for the treatment of, the symptoms such as headache is dizzy, agitation is nervous disappear completely, continue to take a course for the treatment of to consolidate, within 1 year so far, have a surplus without recurrence.
Treat in 233 examples, clinical recovery 156 example, effective 55 examples, effective 17 examples, total effective rate 97.9%.
Claims (8)
1. the migrainous medicine for the treatment of, it is characterized in that, comprise following composition: Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Scutellariae, Rhizoma Et Radix Notopterygii, Radix Puerariae, Radix Platycodonis, Herba Pogostemonis, Poria, the Radix Angelicae Dahuricae, Folium Perillae, Carapax Trionycis, Semen Cassiae, Radix Glycyrrhizae, Herba Asari, Rhizoma Atractylodis, Radix Saposhnikoviae, Radix Ophiopogonis.
2. one according to claim 1 treats migrainous medicine, it is characterized in that, comprise following composition by weight: Rhizoma Gastrodiae 1-10 part, Radix Polygoni Multiflori Preparata 1-10 part, Rhizoma Chuanxiong 1-10 part, Radix Angelicae Sinensis 1-10 part, Radix Astragali 1-10 part, Rhizoma Et Radix Notopterygii 1-10 part, Radix Puerariae 1-10 part, Radix Platycodonis 1-10 part, Herba Pogostemonis 1-10 part, Poria 1-10 part, Radix Angelicae Dahuricae 1-10 part, Folium Perillae 1-10 part, Carapax Trionycis 1-10 part, Semen Cassiae 1-10 part, Radix Glycyrrhizae 1-10 part, Herba Asari 1-10 part, Rhizoma Atractylodis 1-10 part, Radix Saposhnikoviae 1-10 part, Radix Ophiopogonis 1-10 part.
3. one according to claim 2 treats migrainous medicine, it is characterized in that, comprise following composition by weight: Rhizoma Gastrodiae 3-5 part, Radix Polygoni Multiflori Preparata 2-4 part, Rhizoma Chuanxiong 5-8 part, Radix Angelicae Sinensis 4-6 part, Radix Astragali 2-4 part, Rhizoma Et Radix Notopterygii 4-6 part, Radix Puerariae 6-10 part, Radix Platycodonis 4-6 part, Herba Pogostemonis 2-4 part, Poria 3-5 part, Radix Angelicae Dahuricae 4-6 part, Folium Perillae 3-5 part, Carapax Trionycis 3-5 part, Semen Cassiae 4-6 part, Radix Glycyrrhizae 4-8 part, Herba Asari 2-4 part, Rhizoma Atractylodis 2-4 part, Radix Saposhnikoviae 3-5 part, Radix Ophiopogonis 2-4 part.
4. one according to claim 3 treats migrainous medicine, it is characterized in that, comprise following composition by weight: 4 parts, Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata 3 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 5 parts, the Radix Astragali 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Puerariae 8 parts, Radix Platycodonis 5 parts, Herba Pogostemonis 3 parts, 4 parts, Poria, the Radix Angelicae Dahuricae 5 parts, Folium Perillae 4 parts, Carapax Trionycis 4 parts, Semen Cassiae 5 parts, 6 parts, Radix Glycyrrhizae, Herba Asari 3 parts, Rhizoma Atractylodis 3 parts, Radix Saposhnikoviae 4 parts, Radix Ophiopogonis 3 parts.
5. one according to claim 3 treats migrainous medicine, it is characterized in that, also comprises following composition by weight: Fructus Evodiae 3-6 part.
6. one according to claim 5 treats migrainous medicine, it is characterized in that, comprise following composition by weight: 4 parts, Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata 3 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 5 parts, the Radix Astragali 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Puerariae 8 parts, Radix Platycodonis 5 parts, Herba Pogostemonis 3 parts, 4 parts, Poria, the Radix Angelicae Dahuricae 5 parts, Folium Perillae 4 parts, Carapax Trionycis 4 parts, Semen Cassiae 5 parts, 6 parts, Radix Glycyrrhizae, Herba Asari 3 parts, Rhizoma Atractylodis 3 parts, Radix Saposhnikoviae 4 parts, Radix Ophiopogonis 3 parts, Fructus Evodiae 5 parts.
7. one according to claim 5 treats migrainous medicine, it is characterized in that, also comprises following composition by weight: Scorpio 4-6 part, Concha Ostreae 6-10 part.
8. one according to claim 5 treats migrainous medicine, it is characterized in that, comprise following composition by weight: 4 parts, Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata 3 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 5 parts, the Radix Astragali 3 parts, Rhizoma Et Radix Notopterygii 5 parts, Radix Puerariae 8 parts, Radix Platycodonis 5 parts, Herba Pogostemonis 3 parts, 4 parts, Poria, the Radix Angelicae Dahuricae 5 parts, Folium Perillae 4 parts, Carapax Trionycis 4 parts, Semen Cassiae 5 parts, 6 parts, Radix Glycyrrhizae, Herba Asari 3 parts, Rhizoma Atractylodis 3 parts, Radix Saposhnikoviae 4 parts, Radix Ophiopogonis 3 parts, Fructus Evodiae 5 parts, Scorpio 4 parts, Concha Ostreae 8 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510774428.6A CN105250737A (en) | 2015-11-13 | 2015-11-13 | Medicine for treating migraine |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510774428.6A CN105250737A (en) | 2015-11-13 | 2015-11-13 | Medicine for treating migraine |
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| CN105250737A true CN105250737A (en) | 2016-01-20 |
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| CN201510774428.6A Pending CN105250737A (en) | 2015-11-13 | 2015-11-13 | Medicine for treating migraine |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103566197A (en) * | 2012-08-03 | 2014-02-12 | 天津太平洋制药有限公司 | Medicament for treating migraine |
| CN104524367A (en) * | 2014-12-19 | 2015-04-22 | 魏波 | Traditional Chinese medicine composition for treating neurological migraine |
-
2015
- 2015-11-13 CN CN201510774428.6A patent/CN105250737A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103566197A (en) * | 2012-08-03 | 2014-02-12 | 天津太平洋制药有限公司 | Medicament for treating migraine |
| CN104524367A (en) * | 2014-12-19 | 2015-04-22 | 魏波 | Traditional Chinese medicine composition for treating neurological migraine |
Non-Patent Citations (1)
| Title |
|---|
| 储照虎等: "清上蠲痛颗粒治疗偏头痛的临床研究", 《中国临床药理学与治疗学》 * |
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Application publication date: 20160120 |