CN105250535A - Herba taxilli pharmaceutical composition for relieving adverse reaction generated by local anaesthesia and preparation method of pharmaceutical composition - Google Patents

Abstract

The invention provides a herba taxilli pharmaceutical composition for relieving adverse reaction generated by local anaesthesia. The pharmaceutical composition is prepared from the following components by weight: 8-12g of herba taxilli, 5-10g of cortex acanthopanacis, 15-25g of dried rehmannia roots, 1-3g of tripterygium glycosides, 5-10g of mulberry twig, 2-5g of artemisia apiacea, 2-5g of pokeberry roots, 1-3g of felwort, 3-8g of scrophularia ningpoensis, 2-5g of lygodium japonicum, 2-5g of akebiaquinata, 1-3g of radix sophorae tonkinensis, 2-5g of flos eriocauli, 3-5g of cimicifugae foetidae, 5-13g of sedum sarmentosum, 1-2g of piper cubeba, 5-8g of lychee seeds, 2-5g of dalbergia odorifera and 3-6g of folium artemisiae argyi. The pharmaceutical composition plays an obvious alleviating role on joint, waist and knee pain, weak muscles and bones and anemofrigid-damp arthralgia generated after anesthesia, and is low in cost, good in treatment effect, significant in effect on superficial surgeries or local anaesthesia, and suitable for popularization and application.

Description

Herba Taxilli is alleviated local anesthesia and is produced pharmaceutical composition of untoward reaction and preparation method thereof

Technical field

The present invention relates to the anesthesia field of Chinese medicines, specifically a kind of Herba Taxilli alleviates pharmaceutical composition of local anesthesia generation untoward reaction and preparation method thereof.

Background technology

Under local anesthetic effect, neural and mainly utilize other of sodium channel stress film, local anesthetic is weak base, because the reason of dissolubility and stability, because local anesthetic usually makes salt in clinical practice, the side effect of nervus centralis, blood circulation can be caused in vivo, anemia, congestion, heart failure, renal hypofunction, even can cause cardiac arrest, for this reason, develop a kind of Herba Taxilli and alleviate the pharmaceutical composition that local anesthesia produces untoward reaction.

Summary of the invention

The invention provides a kind of Herba Taxilli and alleviate pharmaceutical composition of local anesthesia generation untoward reaction and preparation method thereof, make it have the untoward reaction produced for local anesthesia and effectively alleviated.

The present invention is by the following technical solutions: Herba Taxilli alleviates the pharmaceutical composition that local anesthesia produces untoward reaction, and it is made up by weight ratio of following component:

Herba Taxilli 8-12g, Cortex Acanthopancis 5-10g, Radix Rehmanniae 15-25g, Radix Tripterygii Wilfordii 1-3g,

Ramulus Mori 5-10g, Herba Artemisiae Annuae 2-5g, Radix Phytolaccae 2-5g, Radix Gentianae 1-3g, Radix Scrophulariae 3-8g,

Spora Lygodii 2-5g, Caulis Akebiae 2-5g, Radix Sophorae Tonkinensis 1-3g, Flos Eriocauli 2-5g, Rhizoma Cimicifugae 3-5g,

Herba Sedi 5-13g, Fructus Litseae 1-2g, Semen Litchi 5-8g, Lignum Dalbergiae Odoriferae 2-5g, Folium Artemisiae Argyi 3-6g;

Its preparation method is as follows:

(1). will state weight portion component and pulverize 60-120 order through fine grinding machine, dry in the sun, temperature is in 60-85 DEG C;

(2). immersing content is in 50 DEG C of ethanol, ten, filters;

(3). liquid closed encapsulation is poured in container for subsequent use after 30-45 day.

Concrete, Herba Taxilli alleviates the pharmaceutical composition that local anesthesia produces untoward reaction, and it is made up by weight ratio of following component:

Herba Taxilli 10g, Cortex Acanthopancis 8g, Radix Rehmanniae 19g, Radix Tripterygii Wilfordii 2g, Ramulus Mori 7g,

Herba Artemisiae Annuae 4g, Radix Phytolaccae 3.5, Radix Gentianae 2.5g, Radix Scrophulariae 4g, Spora Lygodii 4g,

Caulis Akebiae 3g, Radix Sophorae Tonkinensis 3g, Flos Eriocauli 3g, Rhizoma Cimicifugae 4g, Herba Sedi 7g,

Fructus Litseae 2g, Semen Litchi 7g, Lignum Dalbergiae Odoriferae 3g, Folium Artemisiae Argyi 4g.

In formula of the present invention, Herba Taxilli has the meridian dredging, beneficial blood, invigorating the liver and kidney, bone and muscle strengthening.

Cortex Acanthopancis has wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, Bi condition, and muscles and bones flaccidity is soft, the effect of inducing diuresis to remove edema.

Radix Rehmanniae: fever due to yin deficiency, impairment of YIN, crimson tongue excessive thirst, a speckle dermexanthesis, haematemesis, epistaxis, laryngopharynx swelling and pain, Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.

Radix Tripterygii Wilfordii, returns liver, kidney channel.Effect expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, reducing swelling and alleviating pain, removing toxic substances parasite killing, for damp and hot tuberosity, the long-pending poison of carcinoma, the effect such as antitumor, antiinflammatory.

Ramulus Mori, wind-damp dispelling, sharp joint, row aqueous vapor, spasm of the limbs.

Herba Artemisiae Annuae, Immunie-Modulating, promotes the immunization of body cell, resisting pathogenic microbes effect.

Radix Phytolaccae, relieves oedema or abdominal distension through diuresis or purgation, eliminating stagnation, harnesses the river swollen.

Radix Gentianae, heat clearing and damp drying, eliminating pathogen in the liver is calmed the frightened, and feeling of fullness in the head is had a headache; Conjunctival congestion and swelling pain; Deaf ear swells; Hypochondriac pain bitter taste; Calentura convulsion with spasms.

Radix Scrophulariae, clearing away heat and cooling blood; Nourishing YIN to lower pathogenic fire; Detoxicating and resolving stagnation of pathogens.

Spora Lygodii, eliminating damp-heat, treating stranguria pain relieving.

Caulis Akebiae, clear away heart-fire relieving restlessness, edema, vexed dark coloured urine, damp and hot arthralgia pain.

Radix Sophorae Tonkinensis, heat-clearing and toxic substances removing, effect of detumescence sore-throat relieving, is usually used in fire-toxin and pents up.

Flos Eriocauli, dispelling wind and heat pathogens, effect of wind-heat of liver channel, conjunctival congestion and swelling pain, improving acuity of vision and removing nebula.

Rhizoma Cimicifugae, sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, wards off warm disease.

Herba Sedi, clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling; Hemostasis is nourished blood.

Fructus Litseae, warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain, colic of cold type is suffered from abdominal pain, stagnancy of cold-damp.

Semen Litchi, promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.

Lignum Dalbergiae Odoriferae, has analgesic activity.

Folium Artemisiae Argyi, returns liver,spleen,kidney warp, warming the meridian for stopping bleeding, dispersing cold for relieving pain; External removing dampness to relieve itching.

The joint produced after the present invention is directed to anesthesia, soreness of waist and knee joint, muscles and bones flaccidity is weak, and anemofrigid-damp arthralgia plays obvious mitigation, and cost is low, treat control good, act on shallow operation or local anaesthetic effect remarkable, suitable penetration and promotion application.

Detailed description of the invention

Embodiment 1

Herba Taxilli alleviates the pharmaceutical composition that local anesthesia produces untoward reaction, and it is made up by weight ratio of following component:

Herba Taxilli 8g, Cortex Acanthopancis 5g, Radix Rehmanniae 215, Radix Tripterygii Wilfordii 1g, Ramulus Mori 5g, Herba Artemisiae Annuae 2g, Radix Phytolaccae 2g, Radix Gentianae 1g, Radix Scrophulariae 3g, Spora Lygodii 2g, Caulis Akebiae 2-5g, Radix Sophorae Tonkinensis 1g, Flos Eriocauli 2g, Rhizoma Cimicifugae 3g, Herba Sedi 5g, Fructus Litseae 1g, Semen Litchi 5g, Lignum Dalbergiae Odoriferae 2g, Folium Artemisiae Argyi 3g;

Its preparation method is as follows:

(1). will state weight portion component and pulverize 60 orders through fine grinding machine, dry in the sun, temperature is in 60 DEG C;

(2). immersing content is in 50 DEG C of ethanol, ten, filters;

(3). liquid closed encapsulation is poured in container for subsequent use after 30 days.

Embodiment 2

Herba Taxilli alleviates the pharmaceutical composition that local anesthesia produces untoward reaction, and it is made up by weight ratio of following component:

Herba Taxilli 10g, Cortex Acanthopancis 8g, Radix Rehmanniae 19g, Radix Tripterygii Wilfordii 2g, Ramulus Mori 7g,

Herba Artemisiae Annuae 4g, Radix Phytolaccae 3.5, Radix Gentianae 2.5g, Radix Scrophulariae 4g, Spora Lygodii 4g,

Caulis Akebiae 3g, Radix Sophorae Tonkinensis 3g, Flos Eriocauli 3g, Rhizoma Cimicifugae 4g, Herba Sedi 7g,

Fructus Litseae 2g, Semen Litchi 7g, Lignum Dalbergiae Odoriferae 3g, Folium Artemisiae Argyi 4g.

Its preparation method is as follows:

(1). will state weight portion component and pulverize 75 orders through fine grinding machine, dry in the sun, temperature is in 70 DEG C;

(2). immersing content is in 50 DEG C of ethanol, ten, filters;

(3). liquid closed encapsulation is poured in container for subsequent use after 30 days.

Embodiment 3

Herba Taxilli alleviates the pharmaceutical composition that local anesthesia produces untoward reaction, and it is made up by weight ratio of following component:

Herba Taxilli 10g, Cortex Acanthopancis 10g, Radix Rehmanniae 25g, Radix Tripterygii Wilfordii 3g, Ramulus Mori 10g,

Herba Artemisiae Annuae 5g, Radix Phytolaccae 5g, Radix Gentianae 3g, Radix Scrophulariae 8g, Spora Lygodii 5g,

Caulis Akebiae 5g, Radix Sophorae Tonkinensis 3g, Flos Eriocauli 5g, Rhizoma Cimicifugae 5g, Herba Sedi 13g,

Fructus Litseae 2g, Semen Litchi 8g, Lignum Dalbergiae Odoriferae 5g, Folium Artemisiae Argyi 6g;

Its preparation method is as follows:

(1). will state weight portion component and pulverize 120 orders through fine grinding machine, dry in the sun, temperature is in 85 DEG C;

(2). immersing content is in 50 DEG C of ethanol, ten, filters;

(3). liquid closed encapsulation is poured in container for subsequent use after 45 days.

Part not in the detailed description of the invention is known technology, and the usual change that those skilled in the art carries out within the scope of technical solution of the present invention or replacement all should be included in protection scope of the present invention.

Claims (2)

1. Herba Taxilli alleviates the pharmaceutical composition that local anesthesia produces untoward reaction, it is characterized in that: it is made up by weight ratio of following component:

Herba Taxilli 8-12g, Cortex Acanthopancis 5-10g, Radix Rehmanniae 15-25g, Radix Tripterygii Wilfordii 1-3g,

Ramulus Mori 5-10g, Herba Artemisiae Annuae 2-5g, Radix Phytolaccae 2-5g, Radix Gentianae 1-3g, Radix Scrophulariae 3-8g,

Spora Lygodii 2-5g, Caulis Akebiae 2-5g, Radix Sophorae Tonkinensis 1-3g, Flos Eriocauli 2-5g, Rhizoma Cimicifugae 3-5g,

Herba Sedi 5-13g, Fructus Litseae 1-2g, Semen Litchi 5-8g, Lignum Dalbergiae Odoriferae 2-5g, Folium Artemisiae Argyi 3-6g;

Its preparation method is as follows:

(1). will state weight portion component and pulverize 60-120 order through fine grinding machine, dry in the sun, temperature is in 60-85 DEG C;

(2). immersing content is in 50 DEG C of ethanol, ten, filters;

(3). liquid closed encapsulation is poured in container for subsequent use after 30-45 day.

2. Herba Taxilli according to claim 1 alleviates the pharmaceutical composition that local anesthesia produces untoward reaction, it is characterized in that: it is made up by weight ratio of following component:

Herba Taxilli 10g, Cortex Acanthopancis 8g, Radix Rehmanniae 19g, Radix Tripterygii Wilfordii 2g, Ramulus Mori 7g,

Herba Artemisiae Annuae 4g, Radix Phytolaccae 3.5, Radix Gentianae 2.5g, Radix Scrophulariae 4g, Spora Lygodii 4g,

Caulis Akebiae 3g, Radix Sophorae Tonkinensis 3g, Flos Eriocauli 3g, Rhizoma Cimicifugae 4g, Herba Sedi 7g,

Fructus Litseae 2g, Semen Litchi 7g, Lignum Dalbergiae Odoriferae 3g, Folium Artemisiae Argyi 4g.