CN105233427B - Die body and method for the detection of three-dimensional directional radiotherapy eutical system quality control - Google Patents
Die body and method for the detection of three-dimensional directional radiotherapy eutical system quality control Download PDFInfo
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Abstract
The present invention relates to the die body for the detection of three-dimensional directional radiotherapy eutical system quality control and method.Die body portion mainly includes the multisection type body mould being connected by body mould connecting rod, and one end of multisection type body mould has head mould groove, and head mould groove is connected with one end of head mould connecting rod, and the other end of head mould connecting rod is connected with head mould；There is on described head mould head mould plugboard trough；There is on described multisection type body mould X Y-direction plugboard trough, Y Z-direction plugboard trough and ionization chamber plugboard trough.Die body designed by the present invention, by designing brand-new structure, it is achieved that the accurate detection of partes corporis humani position.
Description
Technical field
The present invention relates to field of medical equipment, specifically, relate to a kind of for three-dimensional directional radiotherapy eutical system quality control
The die body of system detection and method.
Background technology
Gamma knife treats system also known as stereotaxis gamma ray emissions, is a kind of fusion the present computer technology, stereotaxis
Technology and surgical technic are in the therapeutic article of one, and gamma ray geometric focusing is concentrated and penetrated in focus by it, disposable,
The tissue destroyed in target spot of lethal, and ray through human normal tissue almost without injury, and dosage falls sharply, therefore
With normal structure boundary clearly, edge is as lancinated, and what people were vivid is referred to as " gamma for its treatment range of exposures
Cutter ".
Along with service life and the increase of number of times, the irradiation precision of gamma knife also can change therewith.And due to radiotherapy in the treatment
Particularity, once occur that bigger error will result in consequence without redemption, and substantially less than therapeutic purposes, the most periodically
The accuracy of checking gamma knife is just particularly important.
In prior art, there is part research in terms of gamma knife accuracy.Such as, Application No. 2010105144241
Chinese patent literature describe a kind of multifunction measuring set for stereotactic radiotherapy, its mainly by die body outer layer,
Internal layer and the multi-functional plug-in unit of die body and foundation ring are constituted, and outer layer and internal layer are screwed and form described survey on foundation ring
The main body of amount device, between each outer layer and internal layer, reserving gaps is in order to insert film, and described internal layer nearly foundation ring end center is pre-
Stay cylindricality circular hole to place described multi-functional plug-in unit.This device is capable of the measurement of specific radiological dose to a certain extent,
But human body cannot be simulated and carry out comprehensive measurement, there is bigger limitation.
The Chinese patent literature of Application No. 2006200270124 provide a kind of radiotherapy apparatus launched field measure and etc. Spot detection
Device, it mainly includes that the underframe plate of adjustable level, underframe plate two ends are respectively perpendicular and connects corresponding supporting plate, and its countershaft connects
The launched field detection plate being formed with film groove between launched field measurement panel and backboard of turning location, launched field is measured panel and is arranged lead
Point labelling and form the wild graticule in square side, band lamp Spot detection die body is set up in the lateral wall of side supporting plate, and detection die body includes
Indicate level, vertical marker line etc. Spot detection pedestal, the fixed overhanging horizontal needle body normal thereto of base central.This device
Can be used in the accuracy detection of radiotherapy apparatus, but cannot detect and penetrate dosage.
And for example saying, the Chinese patent literature of Application No. 2014203478059 provides a kind of dynamic authentication body mould for radiotherapy,
Mainly include simulating the checking body mould of breast pulmonary respiratory activity, controlling the movable cylinder of checking body mould and drive the motor of cylinder；Test
Card body mould includes: removable inner chamber and multilamellar outside organization, has: be made up of the air bag of multiple simulation lobes of the lung in described inner chamber
Test lung, test lung includes symmetrically arranged two air bag groups；Described multiple air bags are respectively by a simulation bronchus and
Main trachea connects, and this main trachea connects with cylinder.The body mould that the program is provided, it is possible to effectively simulate human body breast pulmonary
Breathing state, the breathing being particluarly suitable under chemicotherapy state is verified, but still cannot be used human body whole position radiological dose
Detection checking.
Therefore, a kind of die body how is designed, it is possible to for verifying gamma knife irradiation correct dose on human body and precision, be this
The problem that skilled person needs solution badly.
Summary of the invention
It is an object of the invention to as overcoming above-mentioned the deficiencies in the prior art, it is provided that a kind of for three-dimensional directional radiotherapy eutical system matter
Amount controls the die body of detection.Die body designed by the present invention, by designing brand-new structure, it is achieved that the essence of partes corporis humani position
Really detection.
In order to reach above-mentioned purpose, the present invention adopts the following technical scheme that
A kind of die body for the detection of stereo directional radiotherapy apparatus quality control, including: it is connected by body mould connecting rod
Multisection type body mould, one end of multisection type body mould has head mould groove, and head mould groove is connected with one end of head mould connecting rod, head mould
The other end of connecting rod is connected with head mould；
There is on described head mould head mould plugboard trough；
There is X-Y to plugboard trough, Y-Z on described multisection type body mould to plugboard trough and ionization chamber plugboard trough.
Preferably, described multisection type body mould includes three sections, is Integral mold, the second body mould and the 3rd body mould respectively, three segment bodies
Mould is all run through by body mould connecting rod, and body mould connecting rod end is provided with clamp nut.
Preferably, described ionization chamber plugboard trough is positioned on Integral mold, and Y-Z is positioned on the second body mould to plugboard trough, and X-Y is to inserting
Board slot is positioned on the 3rd body mould.
Preferably, it is inserted with film plate in described head mould plugboard trough.
Preferably, in described head mould plugboard trough, it is inserted with ionization chamber plate, ionization chamber plate has center ionization chamber jack and partially
Center ionization chamber jack.
Preferably, the bottom of multisection type body mould is planar structure.
Preferably, described X-Y is all inserted with film plate to plugboard trough and Y-Z in plugboard trough, and film plate has center
Centring ring；
The outside of centering ring is provided with location hole matrix；
Each location hole matrix is respectively provided with hole, four location, and hole, four location is identical with the distance of centering ring, each location
The line of hole and centering ring the most not with the analysis dead in line of film plate.
Preferably, the gross mass of described multisection type body mould, head mould connecting rod and head mould is 70kg, and material is PMMA.
Present invention also offers a kind of detection method utilizing above-mentioned die body to carry out treating deviations, mainly comprise the steps:
A, will with location hole be unkitted film film plate insert die body, use clinical orientation device, respectively X-Z put down
Face and X-Y plane use CT or MR that die body is scanned location；
B, by image transmitting to TPS, use minimum collimator, make single target spot X-Z plane and X-Y plane radiation plan；In
Heart centring ring, as target spot center, makes film radioactive dose be maintained in the optimum linear region of dosage grey scale curve；
C, film is loaded film plate, insert in die body, perform radiation plan；After having planned, take out film plate,
Position in the Chu Zha hole, hole, location of corresponding film；
D, taking-up film, labelling beam angle；Use Film scanner scanning film, imaging；According to Kong Yu center, location
The geometry site of centring ring determines the position of centering ring；Use film analysis software analysis image, to dose curve
Carry out normalizing, find out the approximation center of circle of the similar round surrounded using 50% isodose curve as irradiation field center；
E, according to the following formula calculating treatment deviations Cv；
In formula:
CvTreatment deviations, unit is millimeter (mm)；
CXIrradiation field center distance in X-axis and between location reference point, unit is millimeter (mm)；
CYIrradiation field center distance in Y-axis and between location reference point, unit is millimeter (mm)；
CZIrradiation field center distance on Z axis and between location reference point, unit is millimeter (mm).
Meanwhile, present invention also offers a kind of detection method utilizing above-mentioned die body to carry out single target spot irradiation field size deviation, main
Comprise the steps:
A, will with location hole be unkitted film film plate insert die body, respectively at X-Z plane and X-Y (or Y-Z)
Plane uses CT to be scanned location；
B, by image transmitting to TPS；Use corresponding collimator, make single target spot radiation plan；Using centering ring as target area
Center, makes film radioactive dose be maintained in the optimum linear region of dosage grey scale curve；
C, film is loaded film plate, insert in die body, perform radiation plan；After having planned, take out film plate,
In location, Chu Zha hole, hole, location；
D, taking-up film, labelling beam angle；Use Film scanner scanning film, imaging；According to Kong Yu center, location
The geometry site of centring ring determines the position of centering ring；
E, use film analysis software analysis image, carry out normalizing to dose curve, find out the axis (X by location reference point
Axle, Y-axis, Z axis) and the intersection point of 50% isodose curve；Measure the distance between intersection point and location reference point, by itself and TPS
In the respective distance that is given compare, calculate irradiation field size deviation S according to the following formulav；
Sv=Sa-Sp
In formula:
SvIrradiation field size deviation, unit is millimeter (mm)；
SaOn film analysis software, bent with the dosage such as 50% by the axis (X-axis, Y-axis, Z axis) of centering ring
Distance between the intersection point of line and location reference point, unit is millimeter (mm)；
SpTPS is given, by the axis (X-axis, Y-axis, Z axis) of centering ring and 50% isodose curve
Intersection point and location reference point between distance, unit is millimeter (mm).
In above two detection method, it is preferred that in described step B, centering ring determines 5 non-co-planar arcs,
Total radian number 500 °.
The invention has the beneficial effects as follows:
(1) gross mass of die body is about about 70kg, close to adult human body's mass, when being positioned on equipment to be detected,
Simulation human body that can be the most true to nature accepts gamma knife radiation, and then solves in prior art, detects the less nothing of equipment quality
The problem of the error that method simulation human body virtual condition causes；
(2) head mould part can be used alone, and is used for the quality control detection of the gamma knife using " headstock " fixing, now
The insert port of plate is positioned at the bottom of head mould；
(3), after head mould part is combined into an entirety by head mould connecting rod and multisection type body mould part, may be used in " face
Cover " the quality control detection of fixing head body all-in-one, now the insert port of plate is positioned at the top of head mould.
(4) the inserting board entry design of head mould, makes this head mould be applicable to different die body fixing meanss, expands the suitable of die body
Use scope.
(5) multisection type body mould part has 3 slots, may be inserted into 3 plates；3 plates by with multisection type body module
Synthesizing an entirety, can once put position when die body is carried out CT scan can complete, and decreases pendulum bit manipulation and Set-up errors.
(6) by arranging off-centre ionization chamber jack, the regional extent of therapeutic dose detection is expanded, to gamma knife treatment
System proposes higher quality control requirement.
(7) film plate is provided with rectangular hole, location and centering ring, and matrix form location pore size distribution is not on axis, no
Affecting agent discharge curve is analyzed；Centering ring position non-punching, its position relies on the geometry position in hole, location and centering ring
Relation of putting judges, eliminates the bundle hole impact on dosage normalizing point；Hole, matrix form location can need to select film according to measurement,
Save measurement cost.
Accompanying drawing explanation
Fig. 1 is the structural representation of the present invention；
Fig. 2 is the schematic cross-sectional view of multisection type body mould in the present invention；
Fig. 3 is the structural representation of film plate in the present invention；
Fig. 4 is the structural representation of ionization chamber plate in the present invention；
In figure: 1, Integral mold, the 2, second body mould, the 3, the 3rd body mould, 4, fixing bolt, 5, head mould, 6, head mould
Plugboard trough, 7, head mould connecting rod, 8, clamp nut, 9, X-Y to plugboard trough, 10, Y-Z to plugboard trough, 11, body mould
Connecting rod, 12, ionization chamber plugboard trough, 13, jack, 14, film plate, 15, hole, location, 16, centering ring,
17, ionization chamber plate, 18, partial center ionization chamber jack, 19, center ionization chamber jack.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is described in detail.
Embodiment: a kind of for stereo directional radiotherapy apparatus quality control detection die body, its structure as shown in Figure 1:
Including the multisection type body mould being connected by body mould connecting rod 11, one end of multisection type body mould has head mould groove, and head mould groove leads to
Crossing fixing bolt 4 detachably to stand with one end of head mould connecting rod 7 and be connected, the other end of head mould connecting rod 7 is as head mould 5
It is connected by fixing bolt 4；
On described head mould 5, there is head mould plugboard trough 6；
There is X-Y to plugboard trough 9, Y-Z on described multisection type body mould to plugboard trough 10 and ionization chamber plugboard trough 12.
With reference to shown in Fig. 2, multisection type body mould includes three sections, is Integral mold the 1, second body mould 2 and the 3rd body mould 3 respectively,
All having jack 13 on three segment body moulds, three individual moulds are connected by body mould connecting rod 11 by jack 13, body mould connecting rod 11 end
Portion is provided with clamp nut 8.
Use the body mould of segmentation structure, Integral mold the 1, second body mould the 2, the 3rd body mould 3, head mould can be roughly divided into even
Extension bar 7 and 5 five parts of head mould, it is simple to disassembled for transport, also allow for assembling at the scene.When a portion is damaged,
Can change by monomer.
Specifically, described ionization chamber plugboard trough 12 is positioned on Integral mold 1, and Y-Z is positioned at the second body mould 2 to plugboard trough 10
On, X-Y is positioned on the 3rd body mould 3 to plugboard trough 9.
As required, may be inserted into film plate 14 or ionization chamber plate 17 in head mould plugboard trough 6.
Wherein, ionization chamber plate 17 have center ionization chamber jack 19 and partial center ionization chamber jack 18.
For the ease of placing on different machines, the bottom of described multisection type body mould is planar structure.
More preferably being chosen as, described X-Y is all inserted with film plate, film plate to plugboard trough 9 and Y-Z in plugboard trough 10
On there is centering ring 16；
The outside of centering ring 16 is provided with location hole matrix；
Each location hole matrix is respectively provided with hole 15, four location, the center of the Center-to-Center centring ring 16 in hole 15, four location
Distance identical, the line of hole, each location 15 and centering ring 16 the most not with the analysis dead in line of film plate.
In order to farthest improve accuracy of detection, the gross mass of described multisection type body mould, head mould connecting rod 7 and head mould 5 is 70kg,
Material is PMMA.The density of PMMA is about 1.18g/cm3, it is sufficiently close to body density.
In the present embodiment, additionally provide and multiple utilize above-mentioned die body to carry out the method detected, be specially as follows.
1.1 for detecting the distance between machine center and irradiation field center.
1.1.1 use treatment system production firm is equipped with special measurement instrument and flushing free film (hereinafter referred to as " film ") are carried out
Detection.
1.1.2 special measurement instrument is placed on the alignment pin of locating support, by production firm, setting is described.
1.1.3 being loaded in special measurement instrument by film, make film be horizontal, the pressing on pressing specific purpose tool, at film
One hole of upper bundle, sends specific purpose tool into predetermined irradiation position with therapeutic bed, selects minimum collimator to be irradiated.
1.1.4 change the film in special measurement instrument, make film be in vertical position, repeat the bundle hole of 1.1.3 and irradiate operation.
1.1.5, after film development, draw the dose distribution in three directions of X, Y, Z axis with Film scanner, calculate three respectively
The distance of irradiation field center and machine center on direction, according between formula (1) calculating machine center and irradiation field center away from
From dv。
In formula:
dvDistance between machine center and irradiation field center, unit is millimeter (mm)；
dXIrradiation field center distance in X-axis and between location reference point, unit is millimeter (mm)；
dYIrradiation field center distance in Y-axis and between location reference point, unit is millimeter (mm)；
dZIrradiation field center distance on Z axis and between location reference point, unit is millimeter (mm)；
1.2 focus close rates
1.2.1 ionization chamber plate is inserted die body, after die body being fixed by clinical method, use CT to be scanned location.
1.2.2 by image transmitting to TPS.Use maximum collimator, make single target spot radiotherapy treatment planning of center ionization chamber jack position.
Effectively being measured by ionization chamber a little as center, target area, the treatment plan time is about 300s.
1.2.3 die body is transferred on therapeutic bed, performs radiation plan.
1.2.4 irradiate after starting, the using dosage instrument cumulative measurement 60s time.Before treatment plan completes, measure three times continuously,
Average and be scaled the absorbed dose rate of Water ball center position as location reference point close rate.
1.3 output repeatability
1.3.1 radiotherapy treatment planning 50% dosage is predisposed to 1Gy, and other is with 1.2.1～1.2.3.
1.3.2 in the overall process performing radiation plan, using dosage instrument measures, the reading R of record doseri。
1.3.3 n=5 radiotherapy treatment planning is performed by above-mentioned steps.
1.3.4 coefficient of variation CV is calculated as output repeatability according to formula (2).
In formula:
RiDoser i & lt survey measurements；
The reading meansigma methods that n time is measured；
N performs the number of times of simulated emission treatment plan, n=5.
1.4 output linearity
1.4.1 formulating 3 radiotherapy treatment plannings, 50% dosage is preset is followed successively by 1Gy, 2Gy and 3Gy, and other is with 1.2.1～1.2.3.
Performing 3 radiotherapy treatment plannings the most successively, in the overall process performing radiation plan, using dosage instrument measures, record
T measured by doseriThe reading R that dosage is preseti, TiIt is respectively 2Gy, 4Gy and 6Gy.
1.4.3 the reading R to doseriMediating recipe quantity reset Ti, use least square error fitting method to obtain following linear relationships formula:
Tc=aRi+b-------------------(3)
In formula:
TcThe dosage that least square error fitting method is obtained is preset, and unit is gray(Gy) (Gy)；
The doser reading R that a least square error fitting method is obtainediConstant, a ≠ 0；
The linear relation constant that b least square error fitting method is obtained.
1.4.4 output linearity L is calculated according to formula (4).
1.5 dose deviations
1.5.1 single target spot dose deviations
1.5.1.1 ionization chamber plate is inserted die body, after die body being fixed by clinical method, use CT to be scanned location.
1.5.1.2 by image transmitting to TPS.Use corresponding collimator, effectively measure an aspect at ionization chamber and make center ionization chamber jack
Position or single target spot radiotherapy treatment planning of off-center ionization chamber jack position, effectively measure ionization chamber a little as in target area
The heart, the 50% preset 5Gy of dosage, use the dose point instrument in TPS to provide the intended dose effectively measuring a position.
1.5.1.3 being transferred on therapeutic bed by die body, the jack of vacant ionization chamber uses equivalent material to fill, and performs radiation plan, makes
Measure with doser.
1.5.1.4 measurement result is scaled the absorbed dose of water, calculates die body center and off-centered according to formula (5) respectively
Dose deviations Dv。
In formula:
DvDose deviations, %；
DaAbsorbed dose actual measured value, unit is gray(Gy) (Gy)；
DpRadiotherapy treatment planning dosage, unit is gray(Gy) (Gy).
1.5.2 Mutiple Targets dose deviations
1.5.2.1 ionization chamber plate is inserted die body, after die body being fixed by clinical method, use CT that die body is scanned
Location.
1.5.2.2 by image transmitting to TPS.Effectively measure a some aspect at ionization chamber and make a radiotherapy treatment planning for 3 target spots, 90% dose
Discharge curve holds center ionization chamber jack, the 50% preset 5Gy of dosage, uses the dose point instrument in TPS to provide and effectively measures a little
The intended dose of position.
1.5.2.3 die body is transferred on therapeutic bed, does not use the jack of ionization chamber to use equivalent material to fill, perform radiation plan,
Using dosage instrument measures.
1.5.2.4 measurement result is scaled the absorbed dose of water, calculates Mutiple Targets dose deviations D according to formula (5)v。
1.6 irradiation field size deviations
1.6.1 single target spot irradiation field size deviation
1.6.1.1 die body will be inserted with the film plate being unkitted film in hole, location, after die body being fixed by clinical method, point
Do not use CT that die body is scanned location at X-Z plane and X-Y (or Y-Z) plane.
1.6.1.2 by location image transmitting to TPS.Use corresponding collimator, make single target spot radiation plan.Film plate center is fixed
Circle position, position, as center, target area, selects suitable intended dose, makes film radioactive dose be maintained at dose curve
1.6.1.3 film is loaded film plate, inserts in die body, perform radiation plan.After having planned, take out film plate,
Position in the Chu Zha hole, hole, location of corresponding film.
1.6.1.4 taking-up film, labelling beam angle.Use Film scanner scanning film.According to hole, location and centering ring
Geometry site determine the position of centering ring.
1.6.1.5 use film analysis software analysis image, dose curve is carried out normalizing, finds out the axis (X by centering ring
Axle, Y-axis, Z axis) and the intersection point of 50% isodose curve, measure the distance between intersection point and centering ring, by itself and TPS
In the respective distance that is given compare, calculate irradiation field size deviation S according to formula (6)v。
Sv=Sa-Sp-------------------(6)
In formula:
SvIrradiation field size deviation, unit is millimeter (mm)；
SaOn film analysis software, bent with the dosage such as 50% by the axis (X-axis, Y-axis, Z axis) of centering ring
Distance between the intersection point of line and location reference point, unit is millimeter (mm)；
SpTPS is given, by the axis (X-axis, Y-axis, Z axis) of centering ring and 50% isodose curve
Intersection point and location reference point between distance, unit is millimeter (mm).
1.6.2 Mutiple Targets irradiation field size deviation
1.6.2.1 die body will be inserted with the film plate being unkitted film in hole, location, after die body being fixed by clinical method, point
Do not use CT that die body is scanned location at X-Z plane and X-Y (or Y-Z) plane.
1.6.2.2 by image transmitting to TPS.The radiotherapy treatment planning of 3 target spots is being made near centering ring position, 90% dose
Discharge curve holds centering ring.Select suitable intended dose, make film radioactive dose be maintained at the optimal line of dose curve
In property region.
1.6.2.3 film is loaded film plate, inserts in die body, perform radiation plan.After having planned, take out film plate,
Position in the Chu Zha hole, hole, location of corresponding film.
1.6.2.4 taking-up film, labelling beam angle.Use Film scanner scanning film.According to hole, location and centralized positioning
The geometry site of circle determines the position of centering ring.
1.6.2.5 use film analysis software analysis image, dose curve is carried out normalizing, finds out the axis (X by centering ring
Axle, Y-axis, Z axis) and the intersection point of 50% isodose curve, measure the distance between intersection point and centering ring, by itself and TPS
In the respective distance that is given compare, calculate Mutiple Targets irradiation field size deviation S according to formula (6)v。
1.7 penumbra deviations
1.7.1 single target spot penumbra deviation
1.7.1.1 with 1.6.1.1～1.6.1.4.
1.7.1.2 use film analysis software analysis image, dose curve is carried out normalizing, finds out the axis (X by location reference point
Axle, Y-axis, Z axis) respectively with 80% isodose curve, the intersection point of 20% isodose curve.Measure the distance between two intersection points,
By it with TPS in the respective distance that is given compare, calculate penumbra deviation according to formula (7).
Pv=Pa-Ps-------------------(7)
In formula:
PvPenumbra deviation, unit is millimeter (mm)；
PaOn film analysis software, bent by dosage such as the axis (X-axis, Y-axis, Z axis) upper 80% of centering ring
Distance between line and 20% isodose curve, unit is millimeter (mm)；
PsTPS is given, by axis (X-axis, Y-axis, Z axis) upper 80% isodose curve of centering ring
And the distance between 20% isodose curve, unit is millimeter (mm).
1.7.2 Mutiple Targets penumbra deviation
1.7.2.1 with 1.6.2.1～1.6.2.4.
1.7.2.2 use film analysis software analysis image, dose curve is carried out normalizing, finds out the axis (X by location reference point
Axle, Y-axis, Z axis) and 80% isodose curve, the intersection point of 20% isodose curve.Measure the distance between two intersection points, by it
Compare with the respective distance be given in TPS, calculate Mutiple Targets penumbra deviation according to formula (7).
2.X-cutter detection method
The accelerator for electron therapy method for testing performance supporting X-cutter Therapeutic mode is carried out according to GB 15213.
2.1 treatment deviations
2.1.1 by inserting die body with the film plate being unkitted film in hole, location, clinical orientation device is used, respectively at X-Z plane
Use CT or MR that die body is scanned location with X-Y (or Y-Z) plane.
2.1.2 by image transmitting to TPS.Use minimum collimator, make single target spot X-Z plane and the radiation of X-Y (or Y-Z) plane
Treatment plan.Using centering ring as target spot center, use 5 non-co-planar arcs, total radian number 500 °, make film be shone
Dosage is maintained in the optimum linear region of dosage grey scale curve.
2.1.3 film is loaded film plate, inserts in die body, perform radiation plan.After having planned, take out film plate,
The location, Chu Zha hole, hole, location of corresponding film.
2.1.4 taking-up film, labelling beam angle.Use Film scanner scanning film, imaging.Fixed according to Kong Yu center, location
The geometry site of position circle determines the position of centering ring.Use film analysis software analysis image, dose curve is entered
Row normalizing, finds out the approximation center of circle of the similar round surrounded using 50% isodose curve as irradiation field center.
2.1.5 treatment deviations C is calculated according to formula (8)v。
In formula:
CvTreatment deviations, unit is millimeter (mm)；
CXIrradiation field center distance in X-axis and between location reference point, unit is millimeter (mm)；
CYIrradiation field center distance in Y-axis and between location reference point, unit is millimeter (mm)；
CZIrradiation field center distance on Z axis and between location reference point, unit is millimeter (mm)；
2.2 dose deviations
2.2.1 single target spot dose deviations
2.2.1.1 ionization chamber plate is inserted die body, use CT that die body is scanned location.
2.2.1.2 by image transmitting to TPS.Optional 1 conventional collimator, makees at the ionization chamber jack position of center or partial center ionization
Single target spot radiotherapy treatment planning at the jack position of room.Ionization chamber is effectively measured a little as center, target area, use 5 non-co-
Face arc, total radian number 500 °, center, target area treatment plan dosage 5Gy.
2.2.1.3 being transferred on therapeutic bed by die body, the jack of vacant ionization chamber uses equivalent material to fill, and performs radiation plan, makes
Measure with doser.
2.2.1.4 measurement result is scaled the absorbed dose of water, calculates die body center and off-centered according to formula (5) respectively
Output dose deviation Dv。
2.2.2 Mutiple Targets dose deviations
2.2.2.1 ionization chamber plate is inserted die body, use CT that die body is scanned location.
2.2.2.2 by image transmitting to TPS.Effectively measure an aspect at ionization chamber and make the radiotherapy treatment planning of 3 target spots.Each target
Point uses 5 non-co-planar arcs, total radian number 500 °.Ionization chamber is effectively measured a little as center, target area, treatment plan dosage
5Gy。
2.2.2.3 die body is transferred on therapeutic bed, does not use the jack of ionization chamber to use equivalent material to fill.Perform radiation plan,
Using dosage instrument measures.
2.2.2.4 measurement result is scaled the absorbed dose of water, calculates Mutiple Targets dose deviations D according to formula (5)v。
2.3 irradiation field size deviations
2.3.1 single target spot irradiation field size deviation
2.3.1.1 die body will be inserted, respectively at X-Z plane and X-Y (or Y-Z) with the film plate being unkitted film in hole, location
Plane uses CT to be scanned location.
2.3.1.2 by image transmitting to TPS.Use corresponding collimator, make single target spot radiation plan.Using centering ring as target area
Center, uses 5 non-co-planar arcs, total radian number 500 °, makes film radioactive dose be maintained at the optimal line of dosage grey scale curve
In property region.
2.3.1.3 film is loaded film plate, inserts in die body, perform radiation plan.After having planned, take out film plate,
In location, Chu Zha hole, hole, location.
2.3.1.4 taking-up film, labelling beam angle.Use Film scanner scanning film, imaging.According to location Kong Yuzhong
The geometry site of heart centring ring determines the position of centering ring.
2.3.1.5 use film analysis software analysis image, dose curve is carried out normalizing, finds out the axis (X by location reference point
Axle, Y-axis, Z axis) and the intersection point of 50% isodose curve.Measure the distance between intersection point and location reference point, by itself and TPS
In the respective distance that is given compare, calculate irradiation field size deviation S according to formula (6)v。
2.3.2 Mutiple Targets irradiation field size deviation
The most same 2.3.1.1.
2.3.2.2 by image transmitting to TPS.The radiotherapy treatment planning of 3 target spots, each target is being made near centering ring position
Point uses 5 non-co-planar arcs, total radian number 500 °, makes film radioactive dose be maintained at the optimum linear district of dosage grey scale curve
In territory.
2.3.2.3 film is loaded film plate, inserts in die body, perform radiation plan.After having planned, take out film plate,
In location, Chu Zha hole, hole, location.
2.3.2.4 taking-up film, labelling beam angle.Use Film scanner scanning film, imaging.According to location Kong Yuzhong
The geometry site of heart centring ring determines the position of centering ring.
2.3.2.5 use film analysis software analysis image, dose curve is carried out normalizing, finds out the axis (X by location reference point
Axle, Y-axis, Z axis) and the intersection point of 50% isodose curve.Measure the distance between intersection point and location reference point, by itself and TPS
In the respective distance that is given compare, calculate Mutiple Targets irradiation field size deviation S according to formula (6)v。
2.4 penumbra deviations
2.4.1 single target spot penumbra deviation
2.4.1.1 with 2.3.1.1～2.3.1.4.
2.4.1.2 use film analysis software analysis image, dose curve is carried out normalizing, finds out the axis (X by location reference point
Axle, Y-axis, Z axis) respectively with 80% isodose curve, the intersection point of 20% isodose curve.Measure the distance between two intersection points,
By it with TPS in the respective distance that is given compare, calculate penumbra deviation according to formula (7).
2.4.2 Mutiple Targets penumbra deviation
2.4.2.1 with 2.3.2.1～2.3.2.4.
2.4.2.2 use film analysis software analysis image, dose curve is carried out normalizing, finds out the axis (X by location reference point
Axle, Y-axis, Z axis) respectively with 80% isodose curve, the intersection point of 20% isodose curve.Measure the distance between two intersection points,
By it with TPS in the respective distance that is given compare, calculate penumbra deviation according to formula (7).
TPS mentioned in this programme, for the English abbreviation of radiotherapy treatment planning system.
Described above to the disclosed embodiments, makes professional and technical personnel in the field be capable of or uses the present invention.To enforcement
The multiple amendment of example will be apparent from for those skilled in the art, and generic principles defined herein is permissible
Without departing from the spirit or scope of the present invention, realize in other embodiments, the part not being described in detail, for
Prior art, does not repeats at this.Therefore, the present invention is not intended to be limited to the embodiments shown herein, and is intended to
Meet the widest scope consistent with principles disclosed herein and feature.
Claims (9)
1. the die body for the detection of three-dimensional directional radiotherapy eutical system quality control, it is characterised in that including: by body mould
The multisection type body mould that connecting rod is connected, one end of multisection type body mould has head mould groove, head mould groove and head mould connecting rod
One end connects, and the other end of head mould connecting rod is connected with head mould；
There is on described head mould head mould plugboard trough；
There is X-Y to plugboard trough, Y-Z on described multisection type body mould to plugboard trough and ionization chamber plugboard trough；
The bottom of multisection type body mould is planar structure.
Die body the most according to claim 1, it is characterised in that described multisection type body mould includes three sections, is first respectively
Body mould, the second body mould and the 3rd body mould, three segment body moulds are all run through by body mould connecting rod, and body mould connecting rod end is provided with fastening
Nut.
Die body the most according to claim 1, it is characterised in that described ionization chamber plugboard trough is positioned on Integral mold, Y-Z
Being positioned on the second body mould to plugboard trough, X-Y is positioned on the 3rd body mould to plugboard trough.
Die body the most according to claim 1, it is characterised in that be inserted with film plate in described head mould plugboard trough.
Die body the most according to claim 1, it is characterised in that be inserted with ionization chamber plate in described head mould plugboard trough, electricity
There is on the plate of room center ionization chamber jack and partial center ionization chamber jack.
Die body the most according to claim 4, it is characterised in that described X-Y to plugboard trough and Y-Z in plugboard trough all
It is inserted with film plate, film plate has centering ring；
The outside of centering ring is provided with location hole matrix；
Each location hole matrix is respectively provided with hole, four location, and hole, four location is identical with the distance of centering ring, each location
The line of hole and centering ring the most not with the analysis dead in line of film plate.
7. one kind utilize die body described in claim 6 carry out treat deviations detection method, it is characterised in that include as
Lower step:
A, will with location hole be unkitted film film plate insert die body, use clinical orientation device, respectively X-Z put down
Face and X-Y plane use CT or MR that die body is scanned location；
B, by image transmitting to TPS, use minimum collimator, make single target spot X-Z plane and X-Y plane radiation plan；In
Heart centring ring, as target spot center, makes film radioactive dose be maintained in the optimum linear region of dosage grey scale curve；
C, film is loaded film plate, insert in die body, perform radiation plan；After having planned, take out film plate,
Position in the Chu Zha hole, hole, location of corresponding film；
D, taking-up film, labelling beam angle；Use Film scanner scanning film, imaging；According to Kong Yu center, location
The geometry site of centring ring determines the position of centering ring；Use film analysis software analysis image, to dose curve
Carry out normalizing, find out the approximation center of circle of the similar round surrounded using 50% isodose curve as irradiation field center；
E, according to the following formula calculating treatment deviations Cv；
In formula:
CvTreatment deviations；
CXIrradiation field center distance in X-axis and between location reference point；
CYIrradiation field center distance in Y-axis and between location reference point；
CZIrradiation field center distance on Z axis and between location reference point.
8. one kind utilizes the detection method that die body described in claim 6 carries out single target spot irradiation field size deviation, it is characterised in that
Comprise the steps:
A, the film plate being unkitted film with hole, location is inserted die body, use CT at X-Z plane and X-Y plane respectively
It is scanned location；
B, by image transmitting to TPS；Use corresponding collimator, make single target spot radiation plan；Using centering ring as target area
Center, uses 5 non-co-planar arcs, total radian number 500 °, makes film radioactive dose be maintained at the optimal line of dosage grey scale curve
In property region；
C, film is loaded film plate, insert in die body, perform radiation plan；After having planned, take out film plate,
In location, Chu Zha hole, hole, location；
D, taking-up film, labelling beam angle；Use Film scanner scanning film, imaging；
Geometry site according to hole, location with centering ring determines the position of centering ring；
E, use film analysis software analysis image, dose curve is carried out normalizing, find out by the axis of location reference point with
The intersection point of 50% isodose curve；Measure the distance between intersection point and location reference point, the respective distance that will provide in itself and TPS
Compare, calculate irradiation field size deviation S according to the following formulav；
Sv=Sa-Sp
In formula:
SvIrradiation field size deviation, unit is millimeter (mm)；
SaOn film analysis software, by the axis of centering ring and the intersection point of 50% isodose curve and location reference
Distance between point；
SpTPS is given, by the axis of centering ring and the intersection point of 50% isodose curve and location reference point
Between distance.
9. according to the detection method described in claim 7 or 8, it is characterised in that in described step B, at centering ring
On determine 5 non-co-planar arcs, total radian number 500 °.
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| GB2555464B (en) * | 2016-10-31 | 2022-04-06 | Elekta Ab | Radiotherapy dose distribution measurement |
| CN111588996B (en) * | 2019-02-21 | 2022-06-07 | 西安大医集团股份有限公司 | Verification device for verification die body and radiotherapy system |
| CN111836665B (en) * | 2019-02-21 | 2022-09-30 | 西安大医集团股份有限公司 | Radiotherapy system and verification device and verification method thereof |
| CN110292390A (en) * | 2019-06-28 | 2019-10-01 | 南京安科医疗科技有限公司 | CT layers of sensitivity curve test body mould Set-up errors bearing calibration |
| CN111329501B (en) * | 2020-03-06 | 2022-04-29 | 北京大学深圳医院 | Morning examination and week examination mould body of CT (computerized tomography) simulation positioning machine |
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| CN200951265Y (en) * | 2006-08-11 | 2007-09-26 | 天津医科大学附属肿瘤医院 | Radiation field measurement and isocenter testing device of radiotherapeutics equipment |
| CN201569746U (en) * | 2009-12-25 | 2010-09-01 | 深圳市海博科技有限公司 | Measuring die body |
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