CN105213757A

CN105213757A - A kind of Chinese medicine composition for the treatment of cyclomastopathy

Info

Publication number: CN105213757A
Application number: CN201510761880.9A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-11-10
Filing date: 2015-11-10
Publication date: 2016-01-06

Abstract

The invention discloses a kind of Chinese medicine composition for the treatment of cyclomastopathy, it is made up of the raw material of Chinese medicine of following weight parts proportioning: Herba Macleayae Cordatae 10, Caulis Sargentodoxae 6, charred Radix Sanguisorbae 10, the Radix Pulsatillae 8, Rhizoma Cimicifugae 12, Semen Vaccariae 6, Folium Perillae 12, Semen Litchi 10, Fructus Foeniculi 8, Folium Artemisiae Argyi 8, Radix Gentianae 13, Herba Cirsii 15, the Cortex Eucommiae 8, Radix Scrophulariae 10, Medulla Junci 10, Radix Achyranthis Bidentatae 8, Placenta Hominis 12, Cortex Cinnamomi 10, Semen Armeniacae Amarum 12, Herba Epimedii 10, Rhizoma Osmundae 12, Fructus Forsythiae 15, Herba Ephedrae 6, Bulbus Fritillariae Cirrhosae 12, Folium Isatidis 5, Herba Moslae 15, Commeline communis 6, Herba Eupatorii 15, Rhizoma Ligustici 5, Herba Verbenae 15.The each crude drug of the present invention, through dialectical compatibility, plays effect of promoting QI to circulate and dispersing the agglomeration of the pathogens, removing obstruction in the collateral to relieve pain altogether, to the effect of cyclomastopathy patient Ke Da treating both the principal and secondary aspects of a disease.

Description

A kind of Chinese medicine composition for the treatment of cyclomastopathy

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of cyclomastopathy.

Background technology

Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy.This sick sickness rate was in the trend risen year by year in the last few years, and the age also more and more becomes younger.Cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, often shows as distending pain of the breast and lump in breast, and pain is common is one-sided or bilateral distending pain of the breast or tenderness, periodically pain, and premenstrua occurs or increases the weight of.Be mainly in 30-50 year women, onset peak is 35-40 year.

The treatment of current cyclomastopathy, mainly based on operative therapy, is generally not easily accepted by patient.The medicine for the treatment of cyclomastopathy also has multiple, conventional Western medicine has hormone antagonist class drug tamoxifen, male sex hormone drug third testis or methyl testosterone and prolactin antagonist medicine, though these medicines have certain curative effect, but the cycle of taking is long, easy recurrence, very easily cause iatrogenic injury, side effect is comparatively large, unsuitable long-term taking.The traditional Chinese medical science forms different prescriptions treat mainly with nourishing blood to suppress the hyperactive liver, regulating QI to relieve pain, hard masses softening and resolving, Bushen Tiaochong medicine, but it is not strong mostly to there is specific aim, and curative effect is definite not, and treatment cycle is long, takes the shortcomings such as inconvenient.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of cyclomastopathy.

The technology used in the present invention solution is:

A kind of Chinese medicine composition for the treatment of cyclomastopathy, it is made up of the raw material of Chinese medicine of following weight parts proportioning: Herba Macleayae Cordatae 10-15, Caulis Sargentodoxae 5-15, charred Radix Sanguisorbae 8-15, Radix Pulsatillae 5-10, Rhizoma Cimicifugae 10-15, Semen Vaccariae 5-20, Folium Perillae 5-13, Semen Litchi 5-15, Fructus Foeniculi 5-10, Folium Artemisiae Argyi 5-10, Radix Gentianae 10-15, Herba Cirsii 7-18, Cortex Eucommiae 2-15, Radix Scrophulariae 6-13, Medulla Junci 7-15, Radix Achyranthis Bidentatae 4-12, Placenta Hominis 6-14, Cortex Cinnamomi 8-17, Semen Armeniacae Amarum 7-14, Herba Epimedii 5-14, Rhizoma Osmundae 5-15, Fructus Forsythiae 10-20, Herba Ephedrae 5-10, Bulbus Fritillariae Cirrhosae 10-20, Folium Isatidis 3-10, Herba Moslae 10-20, Commeline communis 5-10, Herba Eupatorii 10-20, Rhizoma Ligustici 3-15, Herba Verbenae 10-20.

Preferably, the weight of each crude drug is: Herba Macleayae Cordatae 10, Caulis Sargentodoxae 6, charred Radix Sanguisorbae 10, the Radix Pulsatillae 8, Rhizoma Cimicifugae 12, Semen Vaccariae 6, Folium Perillae 12, Semen Litchi 10, Fructus Foeniculi 8, Folium Artemisiae Argyi 8, Radix Gentianae 13, Herba Cirsii 15, the Cortex Eucommiae 8, Radix Scrophulariae 10, Medulla Junci 10, Radix Achyranthis Bidentatae 8, Placenta Hominis 12, Cortex Cinnamomi 10, Semen Armeniacae Amarum 12, Herba Epimedii 10, Rhizoma Osmundae 12, Fructus Forsythiae 15, Herba Ephedrae 6, Bulbus Fritillariae Cirrhosae 12, Folium Isatidis 5, Herba Moslae 15, Commeline communis 6, Herba Eupatorii 15, Rhizoma Ligustici 5, Herba Verbenae 15.

The dosage form of above-mentioned Chinese medicine composition is said peroral dosage form on any one pharmaceutics.Wherein decoction adopts following method to prepare:

Take above all medicine mixing by above-mentioned weight, add 8 times of water gagings, soak 2 hours, heating decoction 1.5 hours, filters to obtain decoction liquor one and residue; Residue adds 8 times of water gagings again, and heating decoction 1 hour, filters to obtain decoction liquor two; Merge decoction liquor one and decoction liquor two, obtain decoction.

Pharmacology of the present invention and effect as follows:

The present invention choose Herba Macleayae Cordatae, Caulis Sargentodoxae, charred Radix Sanguisorbae, the Radix Pulsatillae, Rhizoma Cimicifugae, Semen Vaccariae, Folium Perillae, Semen Litchi, Fructus Foeniculi, Folium Artemisiae Argyi, Radix Gentianae, Herba Cirsii, the Cortex Eucommiae, Radix Scrophulariae, Medulla Junci, Radix Achyranthis Bidentatae, Placenta Hominis, Cortex Cinnamomi, Semen Armeniacae Amarum, Herba Epimedii, Rhizoma Osmundae, Fructus Forsythiae, Herba Ephedrae, Bulbus Fritillariae Cirrhosae, Folium Isatidis, Herba Moslae, Commeline communis, Herba Eupatorii, Rhizoma Ligustici, Herba Verbenae totally 30 taste crude drug be brewed into Chinese medicine decoction.

Wherein, Herba Macleayae Cordatae, removing toxic substances of dispeling the wind, promoting the circulation of QI for relieving swelling, parasite killing.

Caulis Sargentodoxae, has heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, the effect of expellingging wind and relieving convulsion.

Charred Radix Sanguisorbae, cooling blood for hemostasis, removing toxic substances sore.

The Radix Pulsatillae, has effect of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, removing dampness and killing parasites.

Rhizoma Cimicifugae, delivers rash, heat-clearing and toxic substances removing, ascending up spleen-Qi and Yang.

Semen Vaccariae, has promoting blood circulation to restore menstrual flow, and stimulating milk secretion is subsided a swelling, effect of inducing diuresis for treating stranguria syndrome.

Folium Perillae, has diaphoresis cold expelling to separate pathogenic factor in the exterior, effect of promoting the circulation of QI to alleviate the stagnation in middle-JIAO, resolving depression preventing or arresting vomiting.

Semen Litchi, promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.

Fructus Foeniculi, has dispersing cold for relieving pain, effect of regulating qi-flowing for harmonizing stomach.

Folium Artemisiae Argyi, warming the meridian for stopping bleeding, dispersing cold for relieving pain; External removing dampness to relieve itching.

Radix Gentianae, heat clearing and damp drying, eliminating pathogen in the liver is calmed the frightened.

Herba Cirsii, cooling blood for hemostasis, promoting blood circulation and detoxication.

The Cortex Eucommiae, tool invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.

Radix Scrophulariae, clearing away heat and cooling blood, removing toxic substances, eliminating stagnation sore-throat relieving, YIN nourishing.

Medulla Junci, clearing heart fire, inducing diuresis for treating stranguria syndrome.

Radix Achyranthis Bidentatae, nourishing the liver and kidney, strong waist knee joint.

Placenta Hominis, QI invigorating, nourishes blood, benefit essence, deficient, weakness and emaciation, hemoptysis asthma.

Cortex Cinnamomi, has complement sun, warming the spleen and stomach, removing accumulated cold, effect of coronary circulation-promoting pain-relieving and antidiarrheal.

Semen Armeniacae Amarum, relieving cough and asthma, loosening bowel to relieve constipation.

Herba Epimedii, kidney invigorating and YANG supporting, expelling wind and removing dampness.

Rhizoma Osmundae, heat clearing away, removing toxic substances, removing heat from blood, hemostasis.

Fructus Forsythiae, heat clearing away, removing toxic substances, eliminating stagnation, detumescence.

Herba Ephedrae, relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing.

Bulbus Fritillariae Cirrhosae, clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.

Folium Isatidis, heat clearing away, removing toxic substances, removing heat from blood, hemostasis.

Herba Moslae, relieving the exterior syndrome by diaphoresis, removing dampness for regulating stomach, inducing diuresis to remove edema.

Commeline communis, heat clearing away, removing toxic substances, diuresis.

Herba Eupatorii, clearing away summer-heat, wards off dirty, removing dampness, regulating menstruation.

Rhizoma Ligustici, dispels the wind, cold expelling, dehumidifying, pain relieving.

Herba Verbenae, promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, removing toxic substances, inducing diuresis to remove edema.

Full side's compatibility, plays effect of promoting QI to circulate and dispersing the agglomeration of the pathogens, removing obstruction in the collateral to relieve pain altogether, to the effect of cyclomastopathy patient Ke Da treating both the principal and secondary aspects of a disease.

Clinical data

1, physical data:

In clinical data 200 example, 25-35 years old ages, 100 examples; 36-45 years old ages, 70 examples; 46-60 years old ages, 30 examples.

2, pathological conditions:

Patient has a flat lump at the outside upper quadrant of breast, and that lays one's hand on has the tough hard tubercle of beans size, can have tenderness.Lump border owes clear, with surrounding tissue adhesion.Breast can have distending pain, the often growth and decline with susceptible to anger, and the moon of being everlasting is premenstrual to be increased the weight of, and alleviates after menstruation.

3, diagnostic criteria:

Draft according to " People's Republic of China's traditional Chinese medicine industry standard-surgery of Chinese medicine Illnesses Diagnoses criterion of therapeutical effect ".

4, Therapeutic Method: oral decoction of the present invention, every day, potion, 20 days was a course for the treatment of.Serve on 2 courses for the treatment of.

5, efficacy assessment standard:

Cure: lump in breast and pain disappear;

Take a turn for the better: lump in breast reduces, pain relief or disappearance;

Invalid: lump in breast and pain unchanged.

6, therapeutic outcome:

See the following form 1.

Table 1

Case load	Cure	Take a turn for the better	Invalid	Total effective rate
					200	179	21	0	100％

As can be seen from Table 1, medicine of the present invention is to the cure rate of cyclomastopathy patient treatment up to 89.5%, and total effective rate is up to 100%, and therapeutic effect is remarkable.

Detailed description of the invention

Embodiment 1

Each raw material of Chinese medicine is taken by following weight:

Herba Macleayae Cordatae 10, Caulis Sargentodoxae 6, charred Radix Sanguisorbae 10, the Radix Pulsatillae 8, Rhizoma Cimicifugae 12, Semen Vaccariae 6, Folium Perillae 12, Semen Litchi 10, Fructus Foeniculi 8, Folium Artemisiae Argyi 8, Radix Gentianae 13, Herba Cirsii 15, the Cortex Eucommiae 8, Radix Scrophulariae 10, Medulla Junci 10, Radix Achyranthis Bidentatae 8, Placenta Hominis 12, Cortex Cinnamomi 10, Semen Armeniacae Amarum 12, Herba Epimedii 10, Rhizoma Osmundae 12, Fructus Forsythiae 15, Herba Ephedrae 6, Bulbus Fritillariae Cirrhosae 12, Folium Isatidis 5, Herba Moslae 15, Commeline communis 6, Herba Eupatorii 15, Rhizoma Ligustici 5, Herba Verbenae 15.

Preparation method is as follows:

Embodiment 2

Each raw material of Chinese medicine is taken by following weight:

Herba Macleayae Cordatae 15, Caulis Sargentodoxae 5, charred Radix Sanguisorbae 8, the Radix Pulsatillae 10, Rhizoma Cimicifugae 15, Semen Vaccariae 5, Folium Perillae 13, Semen Litchi 5, Fructus Foeniculi 10, Folium Artemisiae Argyi 10, Radix Gentianae 10, Herba Cirsii 18, the Cortex Eucommiae 2, Radix Scrophulariae 6, Medulla Junci 7, Radix Achyranthis Bidentatae 12, Placenta Hominis 14, Cortex Cinnamomi 8, Semen Armeniacae Amarum 7, Herba Epimedii 5, Rhizoma Osmundae 15, Fructus Forsythiae 10, Herba Ephedrae 10, Bulbus Fritillariae Cirrhosae 10, Folium Isatidis 10, Herba Moslae 10, Commeline communis 10, Herba Eupatorii 20, Rhizoma Ligustici 3, Herba Verbenae 20.

Preparation method is with embodiment 1.

Embodiment 3

Each raw material of Chinese medicine is taken by following weight:

Herba Macleayae Cordatae 10, Caulis Sargentodoxae 15, charred Radix Sanguisorbae 15, the Radix Pulsatillae 5, Rhizoma Cimicifugae 10, Semen Vaccariae 20, Folium Perillae 5, Semen Litchi 15, Fructus Foeniculi 5, Folium Artemisiae Argyi 5, Radix Gentianae 15, Herba Cirsii 7, the Cortex Eucommiae 15, Radix Scrophulariae 13, Medulla Junci 15, Radix Achyranthis Bidentatae 4, Placenta Hominis 6, Cortex Cinnamomi 17, Semen Armeniacae Amarum 14, Herba Epimedii 14, Rhizoma Osmundae 5, Fructus Forsythiae 20, Herba Ephedrae 5, Bulbus Fritillariae Cirrhosae 20, Folium Isatidis 3, Herba Moslae 20, Commeline communis 5, Herba Eupatorii 10, Rhizoma Ligustici 15, Herba Verbenae 10.

Preparation method is with embodiment 1.

Claims

1. treat the Chinese medicine composition of cyclomastopathy for one kind, it is characterized in that it is made up of the raw material of Chinese medicine of following weight parts proportioning: Herba Macleayae Cordatae 10-15, Caulis Sargentodoxae 5-15, charred Radix Sanguisorbae 8-15, Radix Pulsatillae 5-10, Rhizoma Cimicifugae 10-15, Semen Vaccariae 5-20, Folium Perillae 5-13, Semen Litchi 5-15, Fructus Foeniculi 5-10, Folium Artemisiae Argyi 5-10, Radix Gentianae 10-15, Herba Cirsii 7-18, Cortex Eucommiae 2-15, Radix Scrophulariae 6-13, Medulla Junci 7-15, Radix Achyranthis Bidentatae 4-12, Placenta Hominis 6-14, Cortex Cinnamomi 8-17, Semen Armeniacae Amarum 7-14, Herba Epimedii 5-14, Rhizoma Osmundae 5-15, Fructus Forsythiae 10-20, Herba Ephedrae 5-10, Bulbus Fritillariae Cirrhosae 10-20, Folium Isatidis 3-10, Herba Moslae 10-20, Commeline communis 5-10, Herba Eupatorii 10-20, Rhizoma Ligustici 3-15, Herba Verbenae 10-20.

2. a kind of Chinese medicine composition for the treatment of cyclomastopathy according to claim 1, is characterized in that the weight of each crude drug is: Herba Macleayae Cordatae 10, Caulis Sargentodoxae 6, charred Radix Sanguisorbae 10, the Radix Pulsatillae 8, Rhizoma Cimicifugae 12, Semen Vaccariae 6, Folium Perillae 12, Semen Litchi 10, Fructus Foeniculi 8, Folium Artemisiae Argyi 8, Radix Gentianae 13, Herba Cirsii 15, the Cortex Eucommiae 8, Radix Scrophulariae 10, Medulla Junci 10, Radix Achyranthis Bidentatae 8, Placenta Hominis 12, Cortex Cinnamomi 10, Semen Armeniacae Amarum 12, Herba Epimedii 10, Rhizoma Osmundae 12, Fructus Forsythiae 15, Herba Ephedrae 6, Bulbus Fritillariae Cirrhosae 12, Folium Isatidis 5, Herba Moslae 15, Commeline communis 6, Herba Eupatorii 15, Rhizoma Ligustici 5, Herba Verbenae 15.