CN105200534A - Composition method of novel static spinning solution and preparation process of composition method - Google Patents
Composition method of novel static spinning solution and preparation process of composition method Download PDFInfo
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- CN105200534A CN105200534A CN201510701964.3A CN201510701964A CN105200534A CN 105200534 A CN105200534 A CN 105200534A CN 201510701964 A CN201510701964 A CN 201510701964A CN 105200534 A CN105200534 A CN 105200534A
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- wound
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Abstract
The invention relates to the composition technology of a disinfecting and sterilizing, scar-restraining and rapid-healing completely-wrapping static spinning medical solution based on a high-voltage static spinning instrument. Three types of inorganic salt of AgNO3, NaAsO2 and KMnO4 are included and have the effects of disinfecting and sterilizing, scar restraining and rapid healing respectively. According to the action mechanism of components in the solution, nanometer Ag particles are contained in static spinning fiber and have an antibacterial effect, As elements are contained and have a scar removal effect, MnO4 ions are contained and have a healing-promoting effect, and a quite good effect on completely wrapping a wound is achieved. The high-voltage static spinning instrument needs to produce cold air plasma jets and can have curative effects of disinfecting and sterilizing, scar restraining and rapid healing, taking-down is easy after the wound is healed, and secondary local damage can be effectively prevented. When a wounded person is accidentally injured, the solution can be locally sprayed, and therefore the effects of wound disinfection treatment, hemostasis, beauty maintaining and the like are achieved.
Description
Patent of the present invention relates to a kind of disinfection based on high-voltage electrostatic spinning instrument, suppresses the complete coated electrostatic spinning medical solution technology of scar, quickly-healing, particularly relates to treatment wound infection, Wound quick healing and the electrostatic spinning medical solution except scar beauty treatment.
Background technology
Present medical market is for the mode of the process majority employing sterilizing bandaging of accident trauma, wrapping process is loaded down with trivial details, not only easily cause secondary injury also very easily meat easily cause healing uneven, produce scar, affect attractive in appearance, to reuse some medicines of scar in the future, because scar has cured, reuse medicine, effect is also not obvious.So in order to reach treatment wound infection, the effect that speed heals and improves looks, develop a kind of disinfection, suppress scar, the medicine of quickly-healing is very necessary, patent of the present invention is based on electrostatic textile instrument, have developed a kind of AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution, by the electrostatic spinning machine containing this solution, wound is processed, thus make treated AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution under the effect of electrostatic weaving instrument, electrostatic spinning is produced at nozzle place, can whole coated wound surface, make it to be evenly distributed on wound, can not free dropping after electrospun fibers all wraps up, also can not be bonded together with the surface of a wound, cause cannot being separated easily.So after wound healing, when taking off, there is good second protection effect for wound, can effectively prevent secondary local damage.Summary, the wounded when receiving unexpected injury, can be locally sprayed with this solution, thus reach the effect for the treatment of wound infection, hemostasis and beauty treatment etc.
Chinese patent " portable atmospheric glow discharge plasma jet and electrostatic spinning integrated device " (application number: 201410704814.3, application publication number: CN104372423A, Shen Qing Publication day: 2015.02.25), disclose portable atmospheric glow discharge plasma jet and electrostatic spinning integrated device, it comprises hand-held insulation crust and inner supply unit, high pressure conversion equipment, plasma producing apparatus and electrostatic spinning generating means.
Patent of invention content
In the middle of the social life of people, injure unexpectedly and often occur, so can be very necessary to the process of wound disinfection sterilization, suppression scar, quickly-healing.This patent has been prepared and have developed a kind of AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution, containing Ag nano particles in electrospun fibers, has antibacterial action (infection of disinfection induction reactance); Containing As element, there is the scar effect of removing (preventing after, large area is stammered), containing MnO4 ion, there is the effect (promotion wound convergence) of Promotive union, for wound completely coatedly have extraordinary effect.
Wound healing is injured unexpectedly after the body injury that causes, under the effect of cytokine profiles, cell mechanism, from inflammation, then through propagation, finally from newly moulding the process forming new cell.This solution is especially for the bacteriological infection after wound, and after healing, wound face is uneven, easily forms scar, and adopts electrostatic spinning technique to be formed coated to wound, thus achieves disinfection to wound, removes scar, quickly-healing.Containing AgNO3/NaAsO2/KMnO4 tri-kinds of inorganic salts in the middle of AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution, they refer and synthesize and chemical reaction can not occur together.
The technical problem that patent of the present invention solves realizes by the following technical solutions:
In the middle of AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution, the sterilization of Ag ion is a kind of nontoxic, tasteless, non-stimulated, free of contamination sterilization ion, when silver ion solution concentration reaches certain concentration, bactericidal action is all had to bacterium, virus, fungi etc., this solution is also choose certain density silver ion as virus killing medicament, can reach desirable effect.
Further, this electrostatic spinning solution has prepared the liquor potassic permanganate of concentration 0.2%, and a large amount of Clinic Cases shows that the liquor potassic permanganate of 0.2% can promote the healing of wound effectively.Potassium permanganate has stronger oxidisability, when reacting with organic matter, can generate manganese dioxide by chemical reaction, manganese dioxide can react with protein and generate new compound, and the high manganese ion in the middle of this compound and potassium permanganate all has astriction.
Further, in this electrostatic spinning solution, containing arsenic element, arsenic element is a kind of element of medicine safely and efficiently that reliably can prevent scar excessive flooding.To some hyper-proliferatives, the cell that the cell cycle is shorter, sodium sulfite has good inhibitory action, suppresses left and right preferably so have for the epidermal cell hyper-proliferative caused due to wound and differentiation.
Further, this electrostatic spinning solution is under electrostatic spinning machine injection, wound is processed, thus make treated AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution under the effect of electrostatic weaving instrument, electrostatic spinning is produced at nozzle place, the invention has the beneficial effects as follows can whole coated wound surface, thus reaches the effect for the treatment of wound infection, hemostasis and beauty treatment etc.
Accompanying drawing explanation
As the design sketch of Fig. 1 this patent AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution under electrostatic spinning machine effect
Detailed description of the invention
Further how under the effect of electrostatic spinning machine, coated being further described is realized to AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution below in conjunction with Figure of description and concrete enforcement.
With reference to Figure of description when receiving unexpected injury, we can inject this solution in electrostatic spinning machine, then electrostatic spinning machine is opened, require that this electrostatic spinning machine need produce cold air plasma jet, ensure that skin can realize disinfection to wound while can not receiving secondary injury, suppress the curative effect of scar, quickly-healing.When this AgNO3/NaAsO2/KMnO4/PAN electrostatic spinning solution as shown in description figure; under the effect of electrostatic spinning machine; first surface is drawn out at spinning nozzle place; first along rectilinear motion; when along rectilinear motion during certain distance, athletic meeting enters the astable stage, at this moment; the movement locus of injected electrostatic spinning solution out can present spiral and swing, and meanwhile injection stream also can by further slenderizing.Produce cold air plasma jet by electrostatic weaving instrument and not only to while the uniform covering of wound realization, the second protection to wound under normal temperature situation can be also ensure that.By the polymeric nanofiber that electrostatic spinning machine ejects under the jet action of highfield, its diameter can be low to moderate tens nanometer, have that intensity is high, continuous print carbon nano-fiber, and can conveniently realize electrospinning fibre in-situ deposition, to wound, there is good coating function.
Claims (2)
1. the matching method of novel electrostatic spinning solution and a preparation process thereof, is characterized in that: for the wound of injuring unexpectedly disinfection, remove scar, the completely coated of quickly-healing have extraordinary effect.When unexpected generation, the electrostatic spinning machine containing this solution is processed wound, thus makes AgNO
3/ NaAsO
2/ KMnO
4/ PAN electrostatic spinning solution produces electrospun fibers under the nozzle of electrostatic weaving instrument is in action of high voltage, can complete coated wound surface, makes it to be evenly distributed on wound.
2. a kind of AgNO according to claim 1
3/ NaAsO
2/ KMnO
4/ PAN electrostatic spinning solution, is characterized in that: it to the disinfection of accident trauma, remove scar, quickly-healing is coated thus reaches the extraordinary effects such as treatment wound infection, hemostasis and beauty treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510701964.3A CN105200534A (en) | 2015-10-23 | 2015-10-23 | Composition method of novel static spinning solution and preparation process of composition method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510701964.3A CN105200534A (en) | 2015-10-23 | 2015-10-23 | Composition method of novel static spinning solution and preparation process of composition method |
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| Publication Number | Publication Date |
|---|---|
| CN105200534A true CN105200534A (en) | 2015-12-30 |
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| CN201510701964.3A Pending CN105200534A (en) | 2015-10-23 | 2015-10-23 | Composition method of novel static spinning solution and preparation process of composition method |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106283397A (en) * | 2016-08-30 | 2017-01-04 | 长春理工大学 | Green emitting electromagnetism three function two-layer composite nano-fiber membrane and preparation method thereof |
| CN106890353A (en) * | 2017-03-31 | 2017-06-27 | 应剑波 | A kind of medical accessory with antibacterial nutritve function |
| CN107199693A (en) * | 2017-04-18 | 2017-09-26 | 华中科技大学 | A kind of integrated jet printing appts for being used to increase and decrease material manufacture |
| CN108239881A (en) * | 2016-12-23 | 2018-07-03 | 中国科学院上海应用物理研究所 | A kind of anti-bacterial fibre and preparation method thereof |
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| CN1313097A (en) * | 2000-03-10 | 2001-09-19 | 史洪雨 | Arsenic yellow ointment |
| US20020001630A1 (en) * | 2000-06-29 | 2002-01-03 | Bae Il Ju | Angiogenesis inhibitor |
| CN1528344A (en) * | 2003-10-17 | 2004-09-15 | 戴兆云 | Use of arsenic compound for preparing medicines for treating skin disease |
| CN1640478A (en) * | 2004-01-06 | 2005-07-20 | 济南市长清区人民医院 | External-use Chinese medicine preparation for treating anal-intestinal disorder and its preparing method |
| CN202968788U (en) * | 2012-11-15 | 2013-06-05 | 西安理工大学 | Handheld portable electrostatic spinning equipment |
| CN104372423A (en) * | 2014-11-28 | 2015-02-25 | 安徽理工大学 | Portable atmosphere glow discharge plasma jet and electrostatic spinning integrated device |
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2015
- 2015-10-23 CN CN201510701964.3A patent/CN105200534A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1313097A (en) * | 2000-03-10 | 2001-09-19 | 史洪雨 | Arsenic yellow ointment |
| US20020001630A1 (en) * | 2000-06-29 | 2002-01-03 | Bae Il Ju | Angiogenesis inhibitor |
| CN1528344A (en) * | 2003-10-17 | 2004-09-15 | 戴兆云 | Use of arsenic compound for preparing medicines for treating skin disease |
| CN1640478A (en) * | 2004-01-06 | 2005-07-20 | 济南市长清区人民医院 | External-use Chinese medicine preparation for treating anal-intestinal disorder and its preparing method |
| CN202968788U (en) * | 2012-11-15 | 2013-06-05 | 西安理工大学 | Handheld portable electrostatic spinning equipment |
| CN104372423A (en) * | 2014-11-28 | 2015-02-25 | 安徽理工大学 | Portable atmosphere glow discharge plasma jet and electrostatic spinning integrated device |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106283397A (en) * | 2016-08-30 | 2017-01-04 | 长春理工大学 | Green emitting electromagnetism three function two-layer composite nano-fiber membrane and preparation method thereof |
| CN108239881A (en) * | 2016-12-23 | 2018-07-03 | 中国科学院上海应用物理研究所 | A kind of anti-bacterial fibre and preparation method thereof |
| CN106890353A (en) * | 2017-03-31 | 2017-06-27 | 应剑波 | A kind of medical accessory with antibacterial nutritve function |
| CN107199693A (en) * | 2017-04-18 | 2017-09-26 | 华中科技大学 | A kind of integrated jet printing appts for being used to increase and decrease material manufacture |
| CN107199693B (en) * | 2017-04-18 | 2019-03-05 | 华中科技大学 | A kind of integrated jet printing appts manufactured for increasing and decreasing material |
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