CN117679650A - Medical plasma equipment and application thereof - Google Patents
Medical plasma equipment and application thereof Download PDFInfo
- Publication number
- CN117679650A CN117679650A CN202410089998.0A CN202410089998A CN117679650A CN 117679650 A CN117679650 A CN 117679650A CN 202410089998 A CN202410089998 A CN 202410089998A CN 117679650 A CN117679650 A CN 117679650A
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- China
- Prior art keywords
- plasma
- medical
- argon
- nitrogen
- gas
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- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 claims abstract description 73
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 56
- 239000007789 gas Substances 0.000 claims abstract description 46
- 229910052786 argon Inorganic materials 0.000 claims abstract description 36
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 26
- 208000002874 Acne Vulgaris Diseases 0.000 claims abstract description 11
- 208000010195 Onychomycosis Diseases 0.000 claims abstract description 11
- 206010000496 acne Diseases 0.000 claims abstract description 11
- 201000005882 tinea unguium Diseases 0.000 claims abstract description 11
- 206010047601 Vitamin B1 deficiency Diseases 0.000 claims abstract description 10
- 208000002894 beriberi Diseases 0.000 claims abstract description 10
- 230000003993 interaction Effects 0.000 claims abstract description 10
- 208000015181 infectious disease Diseases 0.000 claims description 10
- 244000052769 pathogen Species 0.000 claims description 9
- 229910001873 dinitrogen Inorganic materials 0.000 claims description 4
- 206010048031 Wound dehiscence Diseases 0.000 claims description 3
- 238000012423 maintenance Methods 0.000 claims description 3
- 238000012544 monitoring process Methods 0.000 claims description 3
- 230000032683 aging Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 13
- 230000009759 skin aging Effects 0.000 abstract description 5
- 238000005336 cracking Methods 0.000 abstract description 4
- 208000024891 symptom Diseases 0.000 abstract description 4
- 239000002245 particle Substances 0.000 description 17
- 239000003570 air Substances 0.000 description 12
- 239000000243 solution Substances 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 6
- 239000012071 phase Substances 0.000 description 6
- 241000700605 Viruses Species 0.000 description 5
- 239000007791 liquid phase Substances 0.000 description 5
- 206010052428 Wound Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 125000004433 nitrogen atom Chemical group N* 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 206010011409 Cross infection Diseases 0.000 description 3
- 241000233866 Fungi Species 0.000 description 3
- 206010029803 Nosocomial infection Diseases 0.000 description 3
- 230000000149 penetrating effect Effects 0.000 description 3
- 239000012466 permeate Substances 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 125000004430 oxygen atom Chemical group O* 0.000 description 2
- 239000007845 reactive nitrogen species Substances 0.000 description 2
- 239000003642 reactive oxygen metabolite Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000012636 effector Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000000752 ionisation method Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 238000009832 plasma treatment Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
Landscapes
- Electrotherapy Devices (AREA)
Abstract
The invention discloses medical plasma equipment and application thereof, the medical plasma equipment comprises a cabinet, a handle and a man-machine interaction interface are arranged on the cabinet, a gas supply system is arranged in the cabinet, the gas supply system comprises a nitrogen cylinder and an argon cylinder which are stored in a bin in the cabinet, the handle comprises an airflow channel for generating plasma flame with equivalent temperature of about 37 ℃ and a plasma discharge electrode, the plasma discharge electrode is arranged in the airflow channel, nitrogen in the nitrogen cylinder and argon in the argon cylinder are conveyed into the airflow channel through a gas circuit, and a man-machine interaction interface controller for controlling the man-machine interaction interface, a plasma discharge electrode generator for controlling the plasma discharge electrode and a gas source controller for controlling nitrogen flow in the nitrogen cylinder and argon flow in the argon cylinder are also arranged on the cabinet. The medical plasma equipment and the application thereof can improve the symptoms of beriberi, acne, skin aging, wound cracking and onychomycosis without side effect.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to medical plasma equipment and application thereof.
Background
At present, medicines are generally adopted to treat beriberi, acne, skin aging, wound cracking and onychomycosis, however, the mode of medicine treatment is difficult to improve the symptoms without side effects.
Disclosure of Invention
The invention aims to solve the technical problems that: in order to solve the problems in the prior art, a medical plasma device and application thereof are provided, and symptoms such as beriberi, acne, skin aging, wound cracking and onychomycosis are improved under the condition of no side effect.
The technical scheme adopted for solving the technical problems is as follows: the utility model provides a medical plasma equipment, includes the rack, install handle and man-machine interface on the rack, be provided with air feed system in the rack, air feed system includes nitrogen bottle and the argon gas bottle of storage in the rack inner bin, the handle is including the air current passageway and the plasma discharge electrode that are used for producing equivalent temperature plasma flame about 37 degrees, the plasma discharge electrode is installed in the air current passageway, the argon gas in nitrogen bottle and the argon gas bottle is carried through the gas circuit in the air current passageway, still installs on the rack is used for control man-machine interface's man-machine interface controller, is used for controlling plasma discharge electrode generator and be used for controlling nitrogen flow and argon gas source controller in the argon gas bottle in the nitrogen gas bottle.
Further specifically defined, in the above technical scheme, the cabinet is further provided with a main control circuit for controlling the working state of the whole medical plasma device and a reset switch for controlling the restarting of the medical plasma device.
In the technical scheme, a plasma generation power supply and a plasma generation circuit for providing high-voltage and specific-frequency alternating voltage to control the ignition and flame maintenance of plasma are further arranged on the cabinet, and the plasma generation circuit comprises a current limiting resistor enabling the current to be 6-8 milliamperes.
Further specifically defined, the gas supply system further includes an argon flow meter mounted on the gas path for monitoring the flow of argon.
The application of a medical plasma device in the treatment of infections caused by skin pathogens.
Further specifically defined, in the above technical scheme, it is applied in beriberi treatment.
Further specifically defined, in the above technical solutions, its use in the treatment of acne.
Further specifically defined, in the above technical solution, is its use in the treatment of skin ageing.
Further specifically defined is the use of the above technical solution in the treatment of wound dehiscence.
Further specifically defined, in the above technical solution, its use in onychomycosis treatment.
The beneficial effects of the invention are as follows: the medical plasma equipment and the application thereof can directly act on a focus through plasma flame, can kill fungi and viruses deep below the surface of the focus, promote the skin to accelerate the update, achieve better curative effect without other side effects, cause different chemical reactions on gas phase and gas-liquid interface in different plasma discharge forms, different discharge parameters and different gas environments, and generate active particles with different proportions, and the active particles can permeate or dissolve in aqueous solution to cause liquid phase chemical reactions.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present application, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of the operation of the present invention;
FIG. 2 is a schematic view of a medical plasma device;
FIG. 3 is a schematic diagram of a second embodiment of a medical plasma device;
FIG. 4 is a schematic diagram of plasma treatment;
FIG. 5 is a schematic illustration of a disposable therapeutic handle cap fitted over a handle;
FIG. 6 is a schematic diagram II of the disposable therapeutic handle cap fitted over the handle;
fig. 7 is a cross-sectional view of fig. 6.
Reference numerals in the drawings: 1. a cabinet; 2. a handle; 21. an air flow channel; 22. a plasma discharge electrode; 3. a human-computer interaction interface; 4. a nitrogen cylinder; 5. an argon bottle; 6. resetting the switch; 7. a disposable therapeutic handle cap; 71. a handle cap body; 72. and a viewing window.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1, 2 and 3, the medical plasma equipment of the invention comprises a cabinet 1, wherein a handle 2 and a human-computer interaction interface 3 are arranged on the cabinet 1, a gas supply system is arranged in the cabinet 1, and the gas supply system comprises a nitrogen bottle 4 and an argon bottle 5 stored in a bin in the cabinet 1. Referring to fig. 7, the handle 2 includes a gas flow path 21 and a plasma discharge electrode 22 installed in the gas flow path 21, and a mixture gas of nitrogen and argon is passed through the gas flow path 21. Specifically, the handle 2 comprises an air flow channel 21 and a plasma discharge electrode 22 for generating a plasma flame with an equivalent temperature of about 37 degrees, the plasma discharge electrode 22 is arranged in the air flow channel 21, nitrogen in the nitrogen bottle 4 and argon in the argon bottle 5 are conveyed into the air flow channel 21 through an air circuit, and a human-computer interaction interface controller for controlling the human-computer interaction interface 3, a plasma discharge electrode generator for controlling the plasma discharge electrode 22 and an air source controller for controlling the nitrogen flow in the nitrogen bottle 4 and the argon flow in the argon bottle 5 are also arranged on the cabinet 1.
Wherein the equivalent temperature of 37 degrees is generally less than 40 degrees. The cabinet 1 is also provided with a main control circuit for controlling the working state of the whole medical plasma equipment and a reset switch 6 for controlling the restarting of the medical plasma equipment. The cabinet 1 is also provided with a plasma generation power supply and a plasma generation circuit for supplying a high-voltage, alternating voltage with a specific frequency to control the ignition and flame maintenance of plasma. The plasma generating circuit includes a current limiting resistor for making the current be 6-8 milliamperes. The gas supply system also comprises an argon flow meter which is arranged on the gas path and used for monitoring the flow of argon.
Referring to fig. 5, the medical plasma device further comprises a disposable treatment handle cap 7, the disposable treatment handle cap 7 comprises a handle cap body 71 sleeved at the tail of the handle 2, the handle cap body 71 is of a tubular structure penetrating through from front to back, the handle cap body 71 comprises a front end contacted with skin of a patient and a rear end far away from the skin of the patient, the caliber of the front end of the handle cap body 71 is smaller than that of the rear end of the handle cap body 1, and the front end of the handle cap body 71 is in smooth curved surface transitional connection with the rear end of the handle cap body 71. The front end of the handle cap body 71, which is in contact with the skin of the patient, is provided with an observation window 72 which is convenient for a doctor to observe the contact state of the flame and the skin of the patient. Wherein the viewing window 72 is a U-shaped channel opening out. The number of the U-shaped grooves is a plurality of, and the U-shaped grooves are uniformly distributed at the front end of the handle cap body 1. Referring to fig. 6, alternatively, the viewing window 72 is a hole penetrating the thickness direction of the handle cap body 71. The number of holes is a plurality of, and a plurality of holes are distributed near the front end of the handle cap body 71, and a plurality of holes are divided into two parts, one part of holes are uniformly distributed in one circumferential direction of the front end of the handle cap body 71, the other part of holes are uniformly distributed in the other circumferential direction of the front end of the handle cap body 71, holes in the two parts are distributed in a staggered mode, and the holes are round holes. By adopting the disposable treatment handle cap 7, the cost is greatly reduced relative to the replacement of the discharge electrode; one for one treatment, the risk of cross infection is greatly reduced; an observation window 72 is arranged on the upper surface, namely a hole or a groove is arranged, so that a doctor can observe the contact state of flame and skin conveniently; medical plastic materials which are in friendly contact with the skin of a patient are adopted, such as: PC, ABS, etc., injection molding, low in production cost and high in medical safety; when in practical use, the handle cap is sleeved at the tail part of the handle 2 of the medical plasma equipment, and the handle cap is replaced one by one in each treatment, so that cross infection is avoided, namely one for one treatment, and the risk of cross infection is greatly reduced; can be used for treating tinea pedis, acne, skin aging, wound dehiscence, onychomycosis, etc.
The application of the medical plasma equipment, the application of the medical plasma equipment in treating infection caused by skin pathogens, in particular to the application of the medical plasma equipment in beriberi treatment, acne treatment, skin aging treatment, wound cracking treatment and onychomycosis treatment.
The medical plasma equipment and the application thereof aim to directly act on the focus through low-temperature plasma flame, can penetrate into the position below the surface of the focus, kill fungi and viruses and promote the skin to be updated quickly. Achieves better curative effect without other side effects. Different plasma discharge forms, discharge parameters and gas environments can cause different chemical reactions on gas phase and gas-liquid interfaces and generate active particles with different proportions, and the active particles can permeate or dissolve in aqueous solution to cause liquid phase chemical reactions, so that infections caused by bacteria, viruses and the like are killed.
The medical plasma equipment generates plasma through high-voltage electric ionization of argon, and the circuit comprises a current limiting resistor, so that the current is very small and only 6-8 milliamperes, and therefore, the heat generated by the current is very limited (the heat is generated in the process of electric current ionization of gas). In addition, because the gas flow rate is relatively fast (the argon gas flow rate is about 3000 standard cubic centimeters per minute), the high-speed flowing gas takes away heat generated in the ionization process, so that plasma close to the body temperature is generated, namely, the plasma with the temperature of about 37 degrees is generated. When the equipment generates plasma, the gas and current for generating the plasma are monitored in real time through the argon flow meter and the plasma generation power supply, so that the temperature of the plasma is controlled within a safe range, wherein the argon flow meter is arranged on a gas path in the cabinet 1, and the plasma generation power supply is arranged in the cabinet 1. Nitrogen is added into the medical plasma equipment, the nitrogen is used as an acting gas, and the nitrogen and the argon form a reasonable proportion, so that the active oxygen particles (OH free radicals, O atoms, O3 and H2O 2) in the common equipment are added into the gas generated by the equipment, and the active nitrogen atoms (such as NO, NO2-, NO 3-and ONOOH/ONOO-and the like) are greatly increased, thereby achieving better curative effects. The active nitrogen atoms generated by adding nitrogen effectively generate the effect of penetrating into the focus, and the composition has good effects on beriberi, acne, onychomycosis, beauty and infection caused by other pathogens from clinical verification, has wide application prospect, and can promote healing of wounds.
The medical plasma equipment comprises a plasma flame with an equivalent temperature of about 37 ℃, two gases of argon and nitrogen are used, a flow sensor is arranged, and the proportion of the two gases of the argon and the nitrogen is controlled in a closed loop manner; the medical plasma equipment is used for treating infection caused by skin pathogens, the application research is initiated, the plasma is suitable for treating beriberi, acne, onychomycosis and other infections caused by pathogens, namely, medical low-temperature plasma is used for treating beriberi, treating acne, treating onychomycosis and other infections caused by skin pathogens or preventing the infections, specifically, active oxygen particles (OH free radicals, O atoms, O3 and H2O 2) and active nitrogen atoms (such as NO, NO2-, NO 3-and ONOOH/ONOO-and the like) in the plasma generated by the medical plasma equipment can act on affected parts of 5mm under the skin to kill pathogens through experimental study and clinical verification.
The medical plasma equipment and the application thereof have the following advantages: 1) The flame temperature is low, the grounding is reliable, and the equipment is more friendly to patients; 2) Nitrogen is creatively adopted as one of the plasma carriers, and active nitrogen atoms (such as NO, NO2-, NO3-, ONOOH/ONOOH-and the like) are greatly increased, so that better curative effect is achieved; 3) Through clinical tests, the device has good curative effect on treating beriberi, acne, onychomycosis and infection caused by other pathogens.
Referring to fig. 4, the plasma may generate a plurality of gas-phase active particles such as charged particles, excited particles, free radicals, etc., but due to the specificity of biological tissues, the objects to be treated in medical research and application are often immersed in a liquid environment, so that the gas-phase active particles cannot be directly applied to the focus area. However, the gas phase reactive particles of the plasma can enter the aqueous solution to produce a wide variety of liquid phase reactive oxygen species (reactive oxygen species, ROS) and reactive nitrogen species (reactive nitrogen species, RNS), such as: long-life particles such as O3, H2O2, NO2-, NO3-, and short-life particles such as O, OH, NO. These liquid-phase ROS and RNS are believed to be the primary effectors of plasma action on biological cells or tissues. Under the combined action of the particles, the particles directly reach focus, and viruses and bacteria are killed under the condition of not damaging human cells.
The medical plasma equipment and the application thereof can directly act below the surface of a focus through plasma flame, kill fungi and viruses, promote the skin to accelerate the update, achieve better curative effect without other side effects, cause different chemical reactions on gas phase and gas-liquid interfaces through different plasma discharge modes (adapting to different symptoms according to the types of the participated gases), different discharge parameters (voltage, frequency and current) and different gas environments (argon and nitrogen, air, argon and oxygen, oxygen and nitrogen) and generate active particles with different proportions, and the active particles can permeate or dissolve in aqueous solution to cause liquid phase chemical reactions.
The present invention is not limited to the above-mentioned embodiments, and any person skilled in the art, based on the technical solution of the present invention and the inventive concept thereof, can be replaced or changed within the scope of the present invention.
Claims (10)
1. A medical plasma device, characterized in that: including rack (1), install handle (2) and human-computer interaction interface (3) on rack (1), be provided with air feed system in rack (1), air feed system is including storing nitrogen bottle (4) and argon gas bottle (5) in the storehouse in rack (1), handle (2) are including being used for producing the air current passageway (21) and plasma discharge electrode (22) of plasma flame about equivalent temperature 37 degrees, plasma discharge electrode (22) are installed in air current passageway (21), nitrogen gas in nitrogen bottle (4) and argon gas in argon gas bottle (5) are through the gas circuit conveying to in air current passageway (21), still install on rack (1) be used for control human-computer interaction interface controller in human-computer interaction interface (3), be used for controlling plasma discharge electrode generator of plasma discharge electrode (22) and be used for controlling nitrogen gas flow and argon gas source controller in argon gas bottle (5) in nitrogen gas bottle (4).
2. The medical plasma device according to claim 1, wherein: the cabinet (1) is also provided with a main control circuit for controlling the working state of the whole medical plasma equipment and a reset switch (6) for controlling the restarting of the medical plasma equipment.
3. The medical plasma device according to claim 1, wherein: the cabinet (1) is also provided with a plasma generation power supply and a plasma generation circuit which are used for providing high-voltage and alternating-current voltage with specific frequency to control the ignition and flame maintenance of plasma, and the plasma generation circuit comprises a current limiting resistor which enables the current to be 6-8 milliamperes.
4. The medical plasma device according to claim 1, wherein: the gas supply system further comprises an argon flow meter which is arranged on the gas path and used for monitoring the flow of argon.
5. Use of a medical plasma device according to claim 1, characterized in that: its use in the treatment of infections caused by skin pathogens.
6. The use of a medical plasma device according to claim 5, characterized in that: it is applied in beriberi treatment.
7. The use of a medical plasma device according to claim 5, characterized in that: its application in treating acne.
8. The use of a medical plasma device according to claim 5, characterized in that: its use in the treatment of skin ageing.
9. The use of a medical plasma device according to claim 5, characterized in that: its use in the treatment of wound dehiscence.
10. The use of a medical plasma device according to claim 5, characterized in that: it can be used for treating onychomycosis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410089998.0A CN117679650A (en) | 2024-01-23 | 2024-01-23 | Medical plasma equipment and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410089998.0A CN117679650A (en) | 2024-01-23 | 2024-01-23 | Medical plasma equipment and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117679650A true CN117679650A (en) | 2024-03-12 |
Family
ID=90137340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202410089998.0A Pending CN117679650A (en) | 2024-01-23 | 2024-01-23 | Medical plasma equipment and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117679650A (en) |
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2024
- 2024-01-23 CN CN202410089998.0A patent/CN117679650A/en active Pending
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