CN105194497A

CN105194497A - Traditional Chinese medicine preparation for treating chronic conjunctivitis

Info

Publication number: CN105194497A
Application number: CN201510662409.4A
Authority: CN
Inventors: 戚金泽; 宋友霞
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-10-09
Filing date: 2015-10-09
Publication date: 2015-12-30

Abstract

The invention discloses a traditional Chinese medicine preparation for treating chronic conjunctivitis. The external reason of the chronic conjunctivitis is wind-heat lingering pathogen retention; the internal reason is steaming stagnated heat of the liver to eyes; wind and heat are taken as main pathogenesis; and deficiency of an eye-nourishing liquid is taken as secondary pathogenesis. Therefore, the traditional Chinese medicines, such as processed purslane seeds, Chinese pennisetum, spiny jujube flower, copper alternanthera, herb of vaginate violet, red sage flowers, smilax nipponica, kunming caulis spatholobi, atripler centralasitica, sargent craneberrybuch branchlet and leaves, beautiful galangal fruits and oriental sesame seeds, with the efficacies of dispelling wind, clearing heat, promoting blood circulation to remove meridian obstruction, nourishing yin and lubricating eyes are selected to be decocted into soup. Through clinical experiments, the total effective rate reaches 96%, and is obviously superior to 70% of that of a control group.

Description

A kind of Chinese medicine preparation for the treatment of chronic conjunctivitis

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine preparation for the treatment of chronic conjunctivitis.

Background technology

Chronic conjunctivitis is commonly encountered diseases, the frequently-occurring disease of ophthalmology.The current treatment to primary disease is generally based on topical antibiotics and antiviral medicament for the eyes.But caused by primary disease not infects directly mostly, but the chronic inflammatory reaction of conjunctival tissue after infection control, thus apply anti-infectives often unsatisfactory curative effect merely, and this type of medicine of prolonged application also can cause the dysbacteriosis of conjunctiva.In clinical, we notice, the conjunctival congestion of chronic conjunctivitis is different from acute conjunctivitis, and it is congested that it shows as light moderate, and color is dark red, the tortuous expansion of comes, and nipple and follicle hypertrophy, meet the diagnostic criteria of the traditional Chinese medical science " syndrome of blood stasis ".Its pathogenesis is heat stagnation stasis, venation impatency, therefore, as taked heat clearing and blood circulation promoting, changes the ruling by law of tired dredging collateral and treats primary disease, more to hit pathogenesis, medicine disease is conformed to than traditional method of dissipating heat and detoxifying.Applicant is through clinical experience for many years, according to the cause of disease, suit the remedy to the case, have developed a kind of Chinese medicine preparation for the treatment of chronic conjunctivitis, this eye drop is red for the order caused by chronic conjunctivitis, eye is dry and astringent, the symptom such as eye itching, scorching hot and asthenopia is rapid-action, determined curative effect, persistent, the features such as diagonal angle conjunctiva is non-stimulated, decrease drug resistance, reduce relapse rate.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of chronic conjunctivitis.Primary disease exopathogenic factor wind heat is remaining evil is detained, interior hot and suffocating by liver on steam in order, the cause of disease is based on wind and heat, and liquid deficiency of supporting order is next, Chinese traditional treatment should wind and heat dispersing, promoting blood circulation to remove obstruction in the collateral, move back red antipruritic, yin nourishing and moisten order.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment chronic conjunctivitis is made up of the Chinese medicine of following weight portion: Semen Portulacae 4-8 part, Herba penniseti 3-8 part, Flos jujubae 6-10 part, Herba Alternantherae Versicoloris 4-8 part, Herba Violae Vaginatae 7-9 part, Flos Lantanae Camarae 4-9 part, Radix Schisandrae Micranthae 4-9 part, Caulis Millettiae Reticulatae 7-10 part, Fructus Atriplicis Sibiricae 7-10 part, Folium et Cacumen Viburni Sargentii 5-9 part, Semen alpinia zerumbet 7-9 part, Semen sesami Niger 3-9 part.

Preferred: Semen Portulacae 6 parts, Herba penniseti 5 parts, Flos jujubae 8 parts, Herba Alternantherae Versicoloris 6 parts, Herba Violae Vaginatae 8 parts, Flos Lantanae Camarae 7 parts, Radix Schisandrae Micranthae 7 parts, Caulis Millettiae Reticulatae 9 parts, Fructus Atriplicis Sibiricae 9 parts, Folium et Cacumen Viburni Sargentii 7 parts, Semen alpinia zerumbet 8 parts, Semen sesami Niger 6 parts.

Preparation method: above Chinese medicine is traditionally made decoction.

Fang Zhong: Semen Portulacae cold removing heat, improving eyesight; Herba penniseti improving eyesight, loose blood; Flos jujubae improving eyesight; Herba Alternantherae Versicoloris heat-clearing and toxic substances removing, removing food stagnancy removing blood stasis; Herba Violae Vaginatae heat-clearing and toxic substances removing, promoting blood circulation and hemostasis; Flos Lantanae Camarae heat-clearing and toxic substances removing, promoting blood circulation and hemostasis; Radix Schisandrae Micranthae promoting flow of qi by warming channel, stomach invigorating dampness removing; Caulis Millettiae Reticulatae nourishing blood to expel wind, dredge the meridian passage; Fructus Atriplicis Sibiricae expelling wind and activating blood circulation, liver heat removing and eyesight improving; Folium et Cacumen Viburni Sargentii dispelling wind and removing obstruction in the collateral, promoting blood circulation and detumescence; Semen alpinia zerumbet dampness cold relieving, spleen invigorating warming the stomach; Semen sesami Niger invigorating the liver and kidney, moistening five ZANG-organs.

Clinical data

1, chronic conjunctivitis out-patient 100 example that physical data is to our hospital during being selected from January, 2012 to 2014 year December, is divided into treatment group and matched group at random, treatment group 50 example, wherein male 30 example, women 20 example; The oldest 64 years old, minimum 21 years old, average 37 years old; Matched group 50 example, wherein male 26 example, women 24 example; The oldest 56 years old, minimum 20 years old, average 35 years old; Two groups in symptom integral, through statistical test P > 0.05, have comparability before sex, age, treatment.

2, diagnostic criteria (1) course of disease is more than 1 month; (2) ophthalmic uncomfortable is based on dry and astringent and foreign body sensation, outer canthus portion gargalesthesia in companion; (3) conjunctival congestion is generally based on fornix portion and palpebral conjunctiva; (4) the visible nipple of palpebral conjunctiva and folliculus; (5) secretions increase is mucus or cellulosic; (6) during merging punctate keratitis, cornea fluorescent staining is positive.

3, Therapeutic Method treatment group uses Chinese medicine preparation of the present invention, take Semen Portulacae 6g, Herba penniseti 5g, Flos jujubae 8g, Herba Alternantherae Versicoloris 6g, Herba Violae Vaginatae 8g, Flos Lantanae Camarae 7g, Radix Schisandrae Micranthae 7g, Caulis Millettiae Reticulatae 9g, Fructus Atriplicis Sibiricae 9g, Folium et Cacumen Viburni Sargentii 7g, Semen alpinia zerumbet 8g, Semen sesami Niger 6g, above-mentioned Chinese medicine decocting is become decoction, every day potion, divide morning, evening takes for twice, within 7 days, is a course for the treatment of; Matched group western medical treatment routinely, two groups treat 3 courses for the treatment of after observe the symptoms.

4, criterion of therapeutical effect recovery from illness: transference cure, examination of eyes finding conjunctiva is smooth; Effective: cardinal symptom disappears substantially, examination of eyes finding conjunctiva is micro-turbid unclear; Invalid: symptom and sign are not improved.

5, therapeutic outcome

Group	n	Recovery from illness	Effective	Invalid	Total effective rate
						Treatment group	50	35	13	2	96％
Matched group	50	25	10	15	70％

Two groups of total effective rate comparing differences have significant (P < 0.05), and treatment group therapeutic effect is obviously better than matched group.In process of the test, all patients all check Liver and kidney function, blood, urine, feces routine and electrocardiogram, no abnormal.A few patients has of short duration local excitation symptom, disappears after a few minutes.

Detailed description of the invention

Embodiment one: take Semen Portulacae 6g, Herba penniseti 5g, Flos jujubae 8g, Herba Alternantherae Versicoloris 6g, Herba Violae Vaginatae 8g, Flos Lantanae Camarae 7g, Radix Schisandrae Micranthae 7g, Caulis Millettiae Reticulatae 9g, Fructus Atriplicis Sibiricae 9g, Folium et Cacumen Viburni Sargentii 7g, Semen alpinia zerumbet 8g, Semen sesami Niger 6g, above-mentioned Chinese medicine decocting is become decoction

Embodiment two: take Semen Portulacae 4g, Herba penniseti 8g, Flos jujubae 6g, Herba Alternantherae Versicoloris 8g, Herba Violae Vaginatae 7g, Flos Lantanae Camarae 4g, Radix Schisandrae Micranthae 9g, Caulis Millettiae Reticulatae 7g, Fructus Atriplicis Sibiricae 10g, Folium et Cacumen Viburni Sargentii 5g, Semen alpinia zerumbet 9g, Semen sesami Niger 3g, above-mentioned Chinese medicine decocting is become decoction

Embodiment three: take Semen Portulacae 8g, Herba penniseti 3g, Flos jujubae 10g, Herba Alternantherae Versicoloris 4g, Herba Violae Vaginatae 9g, Flos Lantanae Camarae 9g, Radix Schisandrae Micranthae 4g, Caulis Millettiae Reticulatae 10g, Fructus Atriplicis Sibiricae 7g, Folium et Cacumen Viburni Sargentii 9g, Semen alpinia zerumbet 7g, Semen sesami Niger 9g, becomes decoction by above-mentioned Chinese medicine decocting.

Claims

1. treat a Chinese medicine preparation for chronic conjunctivitis, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Semen Portulacae 4-8 part, Herba penniseti 3-8 part, Flos jujubae 6-10 part, Herba Alternantherae Versicoloris 4-8 part, Herba Violae Vaginatae 7-9 part, Flos Lantanae Camarae 4-9 part, Radix Schisandrae Micranthae 4-9 part, Caulis Millettiae Reticulatae 7-10 part, Fructus Atriplicis Sibiricae 7-10 part, Folium et Cacumen Viburni Sargentii 5-9 part, Semen alpinia zerumbet 7-9 part, Semen sesami Niger 3-9 part.

2. a kind of Chinese medicine preparation for the treatment of chronic conjunctivitis as claimed in claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Semen Portulacae 6 parts, Herba penniseti 5 parts, Flos jujubae 8 parts, Herba Alternantherae Versicoloris 6 parts, Herba Violae Vaginatae 8 parts, Flos Lantanae Camarae 7 parts, Radix Schisandrae Micranthae 7 parts, Caulis Millettiae Reticulatae 9 parts, Fructus Atriplicis Sibiricae 9 parts, Folium et Cacumen Viburni Sargentii 7 parts, Semen alpinia zerumbet 8 parts, Semen sesami Niger 6 parts.