CN105194211A - Traditional Chinese medicine oral liquid for relieving female chronic fatigue syndrome and preparation method - Google Patents

Traditional Chinese medicine oral liquid for relieving female chronic fatigue syndrome and preparation method Download PDF

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CN105194211A
CN105194211A CN201510755066.6A CN201510755066A CN105194211A CN 105194211 A CN105194211 A CN 105194211A CN 201510755066 A CN201510755066 A CN 201510755066A CN 105194211 A CN105194211 A CN 105194211A
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陈慧珊
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Abstract

The invention discloses a traditional Chinese medicine oral liquid for relieving a female chronic fatigue syndrome and a preparation method. The traditional Chinese medicine oral liquid is prepared from the following raw materials in parts by weight: 17-23 parts of radix pseudostellariae, 27-33 parts of radix pseudostellariae, 27-33 parts of nacre, 27-33 parts of roasted astragalus membranaceus, 12-18 parts of pulp of cornus, 17-23 parts of poria cocos, 12-18 parts of angelica sinensis, 12-18 parts of glossy privet fruits, 12-18 parts of rhizoma atractylodis macrocephalae, 12-18 parts of radix rehmanniae praeparata, 22-28 parts of salviae miltiorrhizae, 17-23 parts of white peony roots, 9-15 parts of schisandra chinensis and 5-11 parts of honey-fried licorice roots. The traditional Chinese medicine oral liquid has the efficacies of nourishing the liver and kidneys, regulating yin and yang, regulating internal organs and tonifying qi and blood, and is a traditional Chinese medicine composition which is safe, reliable, free of toxic or side effect, high in effective component usage rate and fast to act.

Description

A kind of Chinese medicine oral liquid and preparation method alleviating women's chronic fatigue syndrome
Technical field
The present invention relates to a kind of Chinese medicine oral liquid alleviating women's chronic fatigue syndrome, belong to the field of Chinese medicines.
Background technology
Chronic fatigue syndrome female patient is about the twice of male, especially the highest with the white collar women attack rate in 30-45 year, particularly those schoolings are higher, career success, the women that work and family pressure is large, American Centers for Disease Control and Prevention's prediction is said, chronic fatigue syndrome will become one of subject matter of 21 century human health, current China is not also for the large-scale survey of chronic fatigue syndrome, but certainly, those crowds suffering from chronic fatigue syndrome and do not know, considerably beyond present outpatient service quantity, Chinese medicine prevent disease in theory, having a large amount of is the record of disease about fatigue, begin from "Nei Jing", diseases prevention takes care of health opinion " avoiding overstrain ", " impairment of blood by looking for a long time is proposed, excessive rest on bed impairing QI, prolonged sitting injuring the muscles, prolonged standing injuring bones, prolonged walking injuring tendons.Meaning five kinds of over strain "; " key to Diagnosis and Treatment " is referred to as " five kinds of over strain person, the labor of the five internal organs is also "; " General Treatise on the Cause and Symptoms of Diseases " is loaded with will labor, thinks labor, the impairment of the heart caused by overstrain, overwork that care-laden and overworked, thin labor 5 kinds are relevant to feelings will are ill; " the five internal organs person, so store essential substances god vim and vigour soul person is also ", overwork, emotional stress all can hinder dirty causing a disease, therefore have again the lifting manipulation of impairment of the lung caused by overstrain, hepatic asthenia, the impairment of the spleen due to overstrain, the impairment of the heart caused by overstrain, impairment of the kidney caused by overstrain.All refer to the tired disease that work and rest mistake degree or emotional stress cause.The fatigue of visible Chinese medicine not only refers to muscle power overwork, heavy psychology, mental burden are also cause tired key factor, labor is the impairment of QI-blood, muscle, muscles and bones then, therefore disease sees the diseases such as weak breath is unable, muscle bones and muscles pain, mist, emotional stress strains in dirty visible agitation, irritability, depression, anxiety, dizziness, insomnia, have sore throat, the disease such as deficiency-heat, cough, eye are dry, night sweat, " overexertion leading to consumption of QI ", healthy energy is easily empty."Nei Jing" claims: " yang-energy person, bothers and open ", meaning and health do labor excessive time yang-energy floating more in outward, resist ability declines, easy infection exopathogen, therefore the warm virus of the many easy infections of tired person.Also there is ferritic not enough, exopathogen is often invaded, healthy energy exogenous pathogen QI excess, " lack of vital essence resulting in deficiency syndrome " one-tenth naturally tired out is sick, only has clinical report few in number to the TCM investigation of chronic fatigue syndrome, has to think and to belong to insufficiency of the spleen stagnation of liver-QI, or be that deficiency of YIN gas is weak, or deficiency of vital energy folder is strongly fragrant, general many clinical existing cards by patient distinguish its pathogenesis, thus legislationtreat, make pathogen and pathology of tcm and discuss, be summarised as body labor excessive, refreshing labor crosses pole, exhaustion due to sexual indulgence overfrequency, and of a specified duration hinders healthy energy, the impairment of QI-blood, the invading five ZANG-organs, sense pathogen; Also have because natural endowment element is weak, repeatedly invade by exopathogen, damage healthy energy, impaired have at table, at gas, at blood, in dirty difference, thus the card occurred resembles different, itself and the different person of his Anttdisease Mechanism, pathogenic factor in the exterior is that it brings out tired principal element for sick or disorder of emotion repeatedly, then the impairment of the spleen or and kidney, or be impairment of the kidney, impairing the liver, sad etc., visible primary disease reason multiterminal, complicated mechanism, symptom three liang is in groups, weight differs, and the course of disease is very long, current doctor trained in Western medicine still lacks special treatment means, and the traditional Chinese medical science then can obtain obvious curative effect by determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs method.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine oral liquid alleviating women's chronic fatigue syndrome, it has effect of nourishing the liver and kidney, YIN and YANG balance regulating, conditioning viscera, compensate qi and blood.
The present invention is achieved through the following technical solutions:
Alleviate a Chinese medicine oral liquid for women's chronic fatigue syndrome, be made up of following raw material: Radix Pseudostellariae 17-23 part, Rhizoma Dioscoreae 27-33 part, Concha Margaritifera 27-33 part, Radix Astragali Preparata 27-33 part, Fructus Corni 12-18 part, Poria 17-23 part, Radix Angelicae Sinensis 12-18 part, Fructus Ligustri Lucidi 12-18 part, Rhizoma Atractylodis Macrocephalae 12-18 part, Radix Rehmanniae Preparata 12-18 part, Radix Salviae Miltiorrhizae 22-28 part, Radix Paeoniae Alba 17-23 part, Fructus Schisandrae Chinensis 9-15 part, Radix Glycyrrhizae Preparata 5-11 part.
Preferably, each parts by weight of raw materials is: Radix Pseudostellariae 20 parts, Rhizoma Dioscoreae 30 parts, Concha Margaritifera 30 parts, Radix Astragali Preparata 30 parts, Fructus Corni 15 parts, 20 parts, Poria, Radix Angelicae Sinensis 15 parts, Fructus Ligustri Lucidi 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Rehmanniae Preparata 15 parts, Radix Salviae Miltiorrhizae 25 parts, the Radix Paeoniae Alba 20 parts, Fructus Schisandrae Chinensis 12 parts, Radix Glycyrrhizae Preparata 8 parts.
Pharmacological action:
Radix Pseudostellariae: nature and flavor with return through sweet, micro-hardship, flat; Return spleen, lung meridian, function with cure mainly: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung; Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Rhizoma Dioscoreae: nature and flavor with return through: sweet, flat; Return spleen, lung, kidney channel, function with cure mainly: spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission; For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst; Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating; For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Concha Margaritifera: nature and flavor with return through: salty, cold; Return liver, heart channel, function with cure mainly: suppressing the hyperactive liver and subsiding YANG, arresting convulsion improving eyesight; Dizzy for having a headache, irritated insomnia, liver-heat conjunctival congestion, deficiency of the liver blurred vision.
The Radix Astragali: nature and flavor with return through: sweet, temperature; Return lung, spleen channel, function with cure mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation; Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes; Radix Astragali Preparata has QI invigorating invigorating middle warmer, mends fiery supporing yang, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow effect.
Fructus Corni: nature and flavor with return through: sour, puckery, tepor; Return liver, kidney channel, function with cure mainly: liver and kidney tonifying, essence astringing and desertion stemming; For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed; Interior-heat is quenched one's thirst.
Poria: nature and flavor with return through: sweet, light, flat; GUIXIN, lung, spleen, kidney channel, function with cure mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Angelicae Sinensis: nature and flavor with return through sweet, acrid, warm; Return liver, the heart, spleen channel, function with cure mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores; Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow; For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Fructus Ligustri Lucidi: nature and flavor with return through sweet, bitter, cold; Return liver, kidney channel, function with cure mainly: nourishing the liver and kidney, improving eyesight black hair; For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.
The Rhizoma Atractylodis Macrocephalae: nature and flavor with return through: bitter, sweet, temperature; Return spleen, stomach warp, function with cure mainly: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive; For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement; Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive; For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Radix Rehmanniae Preparata: nature and flavor with return through: sweet, tepor; Return liver, kidney channel; Function with cure mainly: nourishing YIN and supplementing blood, beneficial essence fills out marrow; For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
Radix Salviae Miltiorrhizae: nature and flavor with return through: bitter, be slightly cold; GUIXIN, Liver Channel, function with cure mainly: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness; For menoxenia, amenorrhea dysmenorrhea, note of the ancient Chinese abdominal mass is gathered, breast ventral spine pain, pyretic arthralgia pain, and skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
The Radix Paeoniae Alba: nature and flavor with return through: bitter, sour, be slightly cold; Return liver, spleen channel, function with cure mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating; Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Fructus Schisandrae Chinensis: nature and flavor with return through: sour, sweet, temperature; Return lung, the heart, kidney channel, function with cure mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Radix Glycyrrhizae Preparata: meridian distribution of property and flavor: sweet is flat; GUIXIN, lung, spleen, stomach warp; Function cures mainly: spleen reinforcing stomach function regulating, Yiqi and vein recovery; For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse, can separate Radix Aconiti Lateralis Preparata poison, zhigancao decoction has benefiting qi and nourishing yin, and activate yang multiple arteries and veins therapeutic efficiency.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Alleviate a preparation method for the Chinese medicine oral liquid of women's chronic fatigue syndrome, be prepared from by following methods:
(1) get raw material Radix Pseudostellariae, Rhizoma Dioscoreae, Radix Astragali Preparata, Fructus Corni, Poria, Radix Angelicae Sinensis cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(2) get raw material Fructus Ligustri Lucidi, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(3) get the cleaning of raw material Concha Margaritifera, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials weight, and each 1-2 hour collecting decoction, leaves standstill 24-48 hour 6 DEG C time, filters, for subsequent use;
(4) filter in gained filtrate in gained filtrate in step (1) and step (2) and step (3) in gained filtrate feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, revolution 10000-28000r/min, obtain filtrate A, for subsequent use;
(5) filter in step (4) in gained filtrate A feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor B, for subsequent use;
(6) gained liquor B in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste C, for subsequent use;
(7) gained clear paste C in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must alleviate the Chinese medicine oral liquid of women's chronic fatigue syndrome.
Preferably, a kind of preparation method alleviating the Chinese medicine oral liquid of women's chronic fatigue syndrome, is prepared from by following methods:
(1) get raw material Radix Pseudostellariae, Rhizoma Dioscoreae, Radix Astragali Preparata, Fructus Corni, Poria, Radix Angelicae Sinensis cleaning, dry, pulverize, cross 50 mesh sieves, put into rustless steel container and decoct with water secondary, amount of water is 7 times of above-mentioned raw materials gross weight, temperature 65 DEG C, time 2h, filters, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(2) get raw material Fructus Ligustri Lucidi, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata cleaning, dry, pulverize, cross 50 mesh sieves, put into rustless steel container and decoct with water secondary, amount of water is 7 times of above-mentioned raw materials gross weight, temperature 65 DEG C, time 2h, filters, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(3) get the cleaning of raw material Concha Margaritifera, dry, pulverize, cross 60 mesh sieves, put into rustless steel container and decoct with water secondary, amount of water is 5 times of above-mentioned raw materials weight, each 1 hour collecting decoction, 6 DEG C time, leave standstill 24 hours, filters, for subsequent use;
(4) filter in gained filtrate in gained filtrate in step (1) and step (2) and step (3) in gained filtrate feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 75mm, revolution 20000r/min, obtain filtrate A, for subsequent use;
(5) filter in step (4) in gained filtrate A feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.7 μm, and pressure limit is 0.4MPa, and the scope of crossflow velocity is 5m/s, obtains liquor B, for subsequent use;
(6) gained liquor B in step (5) is sent into concentration tank, when being evaporated to 60 DEG C in concentration tank, the clear paste of relative density 1.08, obtains clear paste C, for subsequent use;
(7) gained clear paste C in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 80 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 103 DEG C, time is 15min, after room temperature is down in cooling, warehouse-in is finished product, must alleviate the Chinese medicine oral liquid of women's chronic fatigue syndrome.
Beneficial effect: the present invention has effect of nourishing the liver and kidney, YIN and YANG balance regulating, conditioning viscera, compensate qi and blood, be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, according to pathogenic factor and the Clinical symptoms of women's chronic fatigue syndrome, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine has definite curative effect to alleviation women chronic fatigue syndrome, is a kind of ideal treatment medication of women with chronic fatigue syndrome.
Model case
Case 1: Mrs Du, 46 years old, medical history: feeling of fatigue, Fatique after Sports, sleep disorder, attention lax, depressed, headache, anxious, front and back gait is inharmonious, Fatique after Sports, the moon premenstrually increase the weight of, dizzy, hypothermia, low grade fever, examine as chronic fatigue syndrome, take Drug therapy of the present invention 1 week, after treatment, the conscious above symptom of patient obviously reduces, and takes Drug therapy of the present invention 2 weeks, all symptoms alleviate, and take Drug therapy of the present invention recovery from illness in 3 weeks.
Case 2: Mrs Yu, 33 years old, medical history: regular insomnia, tinnitus, dog-tired, cannot work be absorbed in, examine as chronic fatigue syndrome, take Drug therapy of the present invention 1 week, after treatment, the conscious above symptom of patient obviously reduces, take Drug therapy of the present invention 2 weeks, all symptoms alleviate, and take Drug therapy of the present invention recovery from illness in 3 weeks.
Case 3: Mrs Yin, 47 years old, medical history: feeling of fatigue, Fatique after Sports, sleep disorder, attention lax, depressed, headache, anxious, front and back gait is inharmonious, Fatique after Sports, the moon premenstrually increase the weight of, dizzy, hypothermia, low grade fever, examine as chronic fatigue syndrome, take Drug therapy of the present invention 1 week, after treatment, the conscious above symptom of patient obviously reduces, and takes Drug therapy of the present invention 2 weeks, takes Drug therapy of the present invention recovery from illness in 3 weeks.
Case 4: Mrs Li, 29 years old, medical history: headache, throat pain, muscle arthralgia, weakness, unable, asthenia, feel sleepy, be impatient of, hypomnesis, absent minded, all interest is lacked to anything.Examine as chronic fatigue syndrome, take Drug therapy of the present invention 1 week, after treatment, patient conscious above symptom obviously reduces, and take Drug therapy of the present invention 2 weeks, all symptoms alleviate, and takes Drug therapy of the present invention and fully recovers for 3 weeks.
Case 5: Mrs Jin, 48 years old, medical history: patient felt tired before 10 months, and Progressive symmetric erythrokeratodermia increases the weight of so that affects work, simultaneously with muscle rigidity, arthralgia, paroxysmal headaches, absent minded, examine as chronic fatigue syndrome, take Drug therapy of the present invention 1 week, after treatment, the conscious above symptom of patient obviously reduces, and takes Drug therapy of the present invention 2 weeks, all symptoms alleviate, and take Drug therapy of the present invention recovery from illness in 3 weeks.
Case 6: Mrs Ding, 55 years old, medical history: repeatedly occur malaise, general work can not be completed, feeling of fatigue, Fatique after Sports, sleep disorder, attention lax, depressed, headache, anxious, front and back gait is inharmonious, Fatique after Sports, the moon premenstrually increase the weight of, dizzy, hypothermia, low grade fever, examine as chronic fatigue syndrome, take Drug therapy of the present invention 1 week, after treatment, the conscious above symptom of patient obviously reduces, take Drug therapy of the present invention 2 weeks, all symptoms alleviate, and take Drug therapy of the present invention recovery from illness in 3 weeks.
Clinical data
Physical data: women with chronic fatigue syndrome 50 example, age 26-58 year.
Diagnostic criteria: the diagnostic criteria of chronic fatigue syndrome is as follows: the debilitating fatigue that 1. Main Diagnosis standard occurs recently, does not alleviate because lying up, and every day, activity decreased average was less than 50%, at least continues 6 weeks; 2. through consulting medical history, physical examination and lab testing, the illness that can produce similar symptom is eliminated; Secondary diagnostic criteria is grade fever 37.5-38.6 DEG C 1., can have fear of cold.2. bottleneck throat pain.3. after throat, neck or armpit lymph node pain.4. unaccountable whole-body muscle fatigue and weak.5. muscle sense of discomfort or pain.6. the fatigue before disease after exercise to a certain degree.7. entirely have a headache, and the character of headache, degree, type are different from the headache that the past had.8. migrans arthralgia and without redness and swelling of joints.9. neuropsychological symptom (photophobia, transience blind spot, easily forgets, irritability, thinking difficulty, absent minded, depressed).10. sleep disorder (hypersomnia or insomnia).All possess two of above Main Diagnosis standard and any six of secondary diagnostic criteria and can make a definite diagnosis.
Therapeutic Method: take oral liquid of the present invention, every day 2 times, each 30-40ml one week is a course for the treatment of.
1. curative effect determinate standard fully recovers: General Symptoms disappears completely, and continues more than two months not persons repeatedly.2. effective: General Symptoms obviously alleviates, and continue to alleviate to more than two months persons.3. invalid: General Symptoms is without obvious alleviator.
Therapeutic outcome: by this side treatment women with chronic fatigue syndrome 50 example, 40 examples of wherein fully recovering, effective 8 examples, invalid 2 examples, effective percentage is 96%.
Detailed description of the invention
Embodiment 1
The preparation of women's chronic fatigue syndrome Chinese medicine oral liquid is alleviated in the present invention, and the weight portion of each raw material is: Radix Pseudostellariae 23 parts, Rhizoma Dioscoreae 33 parts, Concha Margaritifera 33 parts, Radix Astragali Preparata 33 parts, Fructus Corni 18 parts, 23 parts, Poria, Radix Angelicae Sinensis 18 parts, Fructus Ligustri Lucidi 18 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Radix Rehmanniae Preparata 18 parts, Radix Salviae Miltiorrhizae 28 parts, the Radix Paeoniae Alba 23 parts, Fructus Schisandrae Chinensis 15 parts, Radix Glycyrrhizae Preparata 11 parts;
Be prepared from by following methods:
(1) get raw material Radix Pseudostellariae, Rhizoma Dioscoreae, Radix Astragali Preparata, Fructus Corni, Poria, Radix Angelicae Sinensis cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(2) get raw material Fructus Ligustri Lucidi, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(3) get the cleaning of raw material Concha Margaritifera, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials weight, and each 1-2 hour collecting decoction, leaves standstill 24-48 hour 6 DEG C time, filters, for subsequent use;
(4) filter in gained filtrate in gained filtrate in step (1) and step (2) and step (3) in gained filtrate feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, revolution 10000-28000r/min, obtain filtrate A, for subsequent use;
(5) filter in step (4) in gained filtrate A feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor B, for subsequent use;
(6) gained liquor B in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste C, for subsequent use;
(7) gained clear paste C in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must alleviate the Chinese medicine oral liquid of women's chronic fatigue syndrome.
Usage: oral, every day 2 times, each 30-40ml.
Embodiment 2
The preparation of women's chronic fatigue syndrome Chinese medicine oral liquid is alleviated in the present invention, and the weight portion of each raw material is: Radix Pseudostellariae 20 parts, Rhizoma Dioscoreae 30 parts, Concha Margaritifera 30 parts, Radix Astragali Preparata 30 parts, Fructus Corni 15 parts, 20 parts, Poria, Radix Angelicae Sinensis 15 parts, Fructus Ligustri Lucidi 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Rehmanniae Preparata 15 parts, Radix Salviae Miltiorrhizae 25 parts, the Radix Paeoniae Alba 20 parts, Fructus Schisandrae Chinensis 12 parts, Radix Glycyrrhizae Preparata 8 parts;
Be prepared from by following methods:
(1) get raw material Radix Pseudostellariae, Rhizoma Dioscoreae, Radix Astragali Preparata, Fructus Corni, Poria, Radix Angelicae Sinensis cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(2) get raw material Fructus Ligustri Lucidi, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(3) get the cleaning of raw material Concha Margaritifera, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials weight, and each 1-2 hour collecting decoction, leaves standstill 24-48 hour 6 DEG C time, filters, for subsequent use;
(4) filter in gained filtrate in gained filtrate in step (1) and step (2) and step (3) in gained filtrate feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, revolution 10000-28000r/min, obtain filtrate A, for subsequent use;
(5) filter in step (4) in gained filtrate A feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor B, for subsequent use;
(6) gained liquor B in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste C, for subsequent use;
(7) gained clear paste C in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must alleviate the Chinese medicine oral liquid of women's chronic fatigue syndrome.
Usage: oral, every day 2 times, each 30-40ml.
Embodiment 3
The preparation of women's chronic fatigue syndrome Chinese medicine oral liquid is alleviated in the present invention, and the weight portion of each raw material is: Radix Pseudostellariae 17 parts, Rhizoma Dioscoreae 27 parts, Margarita 27 parts, Radix Astragali Preparata 27 parts, Fructus Corni 12 parts, 17 parts, Poria, Radix Angelicae Sinensis 12 parts, Fructus Ligustri Lucidi 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Radix Rehmanniae Preparata 12 parts, Radix Salviae Miltiorrhizae 22 parts, the Radix Paeoniae Alba 17 parts, Fructus Schisandrae Chinensis 9 parts, Radix Glycyrrhizae Preparata 5 parts;
Be prepared from by following methods:
(1) get raw material Radix Pseudostellariae, Rhizoma Dioscoreae, Radix Astragali Preparata, Fructus Corni, Poria, Radix Angelicae Sinensis cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(2) get raw material Fructus Ligustri Lucidi, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(3) get the cleaning of raw material Concha Margaritifera, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials weight, and each 1-2 hour collecting decoction, leaves standstill 24-48 hour 6 DEG C time, filters, for subsequent use;
(4) filter in gained filtrate in gained filtrate in step (1) and step (2) and step (3) in gained filtrate feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, revolution 10000-28000r/min, obtain filtrate A, for subsequent use;
(5) filter in step (4) in gained filtrate A feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor B, for subsequent use;
(6) gained liquor B in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste C, for subsequent use;
(7) gained clear paste C in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must alleviate the Chinese medicine oral liquid of women's chronic fatigue syndrome.
Usage: oral, every day 2 times, each 30-40ml.
Embodiment 4
The preparation of women's chronic fatigue syndrome Chinese medicine oral liquid is alleviated in the present invention, and the weight portion of each raw material is: Radix Pseudostellariae 19 parts, Rhizoma Dioscoreae 29 parts, Concha Margaritifera 29 parts, Radix Astragali Preparata 29 parts, Fructus Corni 14 parts, 19 parts, Poria, Radix Angelicae Sinensis 14 parts, Fructus Ligustri Lucidi 14 parts, the Rhizoma Atractylodis Macrocephalae 14 parts, Radix Rehmanniae Preparata 14 parts, Radix Salviae Miltiorrhizae 24 parts, the Radix Paeoniae Alba 19 parts, Fructus Schisandrae Chinensis 11 parts, Radix Glycyrrhizae Preparata 7 parts;
Be prepared from by following methods:
(1) get raw material Radix Pseudostellariae, Rhizoma Dioscoreae, Radix Astragali Preparata, Fructus Corni, Poria, Radix Angelicae Sinensis cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(2) get raw material Fructus Ligustri Lucidi, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(3) get the cleaning of raw material Concha Margaritifera, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials weight, and each 1-2 hour collecting decoction, leaves standstill 24-48 hour 6 DEG C time, filters, for subsequent use;
(4) filter in gained filtrate in gained filtrate in step (1) and step (2) and step (3) in gained filtrate feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, revolution 10000-28000r/min, obtain filtrate A, for subsequent use;
(5) filter in step (4) in gained filtrate A feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor B, for subsequent use;
(6) gained liquor B in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste C, for subsequent use;
(7) gained clear paste C in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must alleviate the Chinese medicine oral liquid of women's chronic fatigue syndrome.
Usage: oral, every day 2 times, each 30-40ml.

Claims (7)

1. alleviate a Chinese medicine oral liquid for women's chronic fatigue syndrome, it is characterized in that: be made up of following raw material: Radix Pseudostellariae 17-23 part, Rhizoma Dioscoreae 27-33 part, Concha Margaritifera 27-33 part, Radix Astragali Preparata 27-33 part, Fructus Corni 12-18 part, Poria 17-23 part, Radix Angelicae Sinensis 12-18 part, Fructus Ligustri Lucidi 12-18 part, Rhizoma Atractylodis Macrocephalae 12-18 part, Radix Rehmanniae Preparata 12-18 part, Radix Salviae Miltiorrhizae 22-28 part, Radix Paeoniae Alba 17-23 part, Fructus Schisandrae Chinensis 9-15 part, Radix Glycyrrhizae Preparata 5-11 part.
2. a kind of Chinese medicine oral liquid alleviating women's chronic fatigue syndrome according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Pseudostellariae 20 parts, Rhizoma Dioscoreae 30 parts, Concha Margaritifera 30 parts, Radix Astragali Preparata 30 parts, Fructus Corni 15 parts, 20 parts, Poria, Radix Angelicae Sinensis 15 parts, Fructus Ligustri Lucidi 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Rehmanniae Preparata 15 parts, Radix Salviae Miltiorrhizae 25 parts, the Radix Paeoniae Alba 20 parts, Fructus Schisandrae Chinensis 12 parts, Radix Glycyrrhizae Preparata 8 parts.
3. a kind of Chinese medicine oral liquid alleviating women's chronic fatigue syndrome according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Pseudostellariae 19 parts, Rhizoma Dioscoreae 29 parts, Concha Margaritifera 29 parts, Radix Astragali Preparata 29 parts, Fructus Corni 14 parts, 19 parts, Poria, Radix Angelicae Sinensis 14 parts, Fructus Ligustri Lucidi 14 parts, the Rhizoma Atractylodis Macrocephalae 14 parts, Radix Rehmanniae Preparata 14 parts, Radix Salviae Miltiorrhizae 24 parts, the Radix Paeoniae Alba 19 parts, Fructus Schisandrae Chinensis 11 parts, Radix Glycyrrhizae Preparata 7 parts.
4. a kind of Chinese medicine oral liquid alleviating women's chronic fatigue syndrome according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Pseudostellariae 23 parts, Rhizoma Dioscoreae 33 parts, Concha Margaritifera 33 parts, Radix Astragali Preparata 33 parts, Fructus Corni 18 parts, 23 parts, Poria, Radix Angelicae Sinensis 18 parts, Fructus Ligustri Lucidi 18 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Radix Rehmanniae Preparata 18 parts, Radix Salviae Miltiorrhizae 28 parts, the Radix Paeoniae Alba 23 parts, Fructus Schisandrae Chinensis 15 parts, Radix Glycyrrhizae Preparata 11 parts.
5. a kind of Chinese medicine oral liquid alleviating women's chronic fatigue syndrome according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Pseudostellariae 17 parts, Rhizoma Dioscoreae 27 parts, Margarita 27 parts, Radix Astragali Preparata 27 parts, Fructus Corni 12 parts, 17 parts, Poria, Radix Angelicae Sinensis 12 parts, Fructus Ligustri Lucidi 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Radix Rehmanniae Preparata 12 parts, Radix Salviae Miltiorrhizae 22 parts, the Radix Paeoniae Alba 17 parts, Fructus Schisandrae Chinensis 9 parts, Radix Glycyrrhizae Preparata 5 parts.
6. a kind of preparation method alleviating the Chinese medicine oral liquid of women's chronic fatigue syndrome according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) get raw material Radix Pseudostellariae, Rhizoma Dioscoreae, Radix Astragali Preparata, Fructus Corni, Poria, Radix Angelicae Sinensis cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(2) get raw material Fructus Ligustri Lucidi, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata cleaning, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials gross weight, temperature 50-95 DEG C, time 1-4h, filter, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(3) get the cleaning of raw material Concha Margaritifera, dry, pulverize, cross 50-60 mesh sieve, put into rustless steel container and decoct with water secondary, amount of water is 6-10 times of above-mentioned raw materials weight, and each 1-2 hour collecting decoction, leaves standstill 24-48 hour 6 DEG C time, filters, for subsequent use;
(4) filter in gained filtrate in gained filtrate in step (1) and step (2) and step (3) in gained filtrate feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, revolution 10000-28000r/min, obtain filtrate A, for subsequent use;
(5) filter in step (4) in gained filtrate A feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor B, for subsequent use;
(6) gained liquor B in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste C, for subsequent use;
(7) gained clear paste C in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must alleviate the Chinese medicine oral liquid of women's chronic fatigue syndrome.
7. a kind of preparation method alleviating the Chinese medicine oral liquid of women's chronic fatigue syndrome according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) get raw material Radix Pseudostellariae, Rhizoma Dioscoreae, Radix Astragali Preparata, Fructus Corni, Poria, Radix Angelicae Sinensis cleaning, dry, pulverize, cross 50 mesh sieves, put into rustless steel container and decoct with water secondary, amount of water is 7 times of above-mentioned raw materials gross weight, temperature 65 DEG C, time 2h, filters, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(2) get raw material Fructus Ligustri Lucidi, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae Preparata cleaning, dry, pulverize, cross 50 mesh sieves, put into rustless steel container and decoct with water secondary, amount of water is 7 times of above-mentioned raw materials gross weight, temperature 65 DEG C, time 2h, filters, obtain filtrate and medicinal residues, dregs pressing is gone out filtrate, and filtrate merges, and abandons medicinal residues, obtain filtrate, for subsequent use;
(3) get the cleaning of raw material Concha Margaritifera, dry, pulverize, cross 60 mesh sieves, put into rustless steel container and decoct with water secondary, amount of water is 5 times of above-mentioned raw materials weight, each 1 hour collecting decoction, 6 DEG C time, leave standstill 24 hours, filters, for subsequent use;
(4) filter in gained filtrate in gained filtrate in step (1) and step (2) and step (3) in gained filtrate feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 75mm, revolution 20000r/min, obtain filtrate A, for subsequent use;
(5) filter in step (4) in gained filtrate A feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.7 μm, and pressure limit is 0.4MPa, and the scope of crossflow velocity is 5m/s, obtains liquor B, for subsequent use;
(6) gained liquor B in step (5) is sent into concentration tank, when being evaporated to 60 DEG C in concentration tank, the clear paste of relative density 1.08, obtains clear paste C, for subsequent use;
(7) gained clear paste C in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 80 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 103 DEG C, time is 15min, after room temperature is down in cooling, warehouse-in is finished product, must alleviate the Chinese medicine oral liquid of women's chronic fatigue syndrome.
CN201510755066.6A 2015-11-09 2015-11-09 Traditional Chinese medicine oral liquid for relieving female chronic fatigue syndrome and preparation method Pending CN105194211A (en)

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