CN105194059A - Traditional Chinese medicine for treating hypomenorrhea after artificial abortion operation - Google Patents
Traditional Chinese medicine for treating hypomenorrhea after artificial abortion operation Download PDFInfo
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Abstract
The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine for treating hypomenorrhea after artificial abortion operation. The traditional Chinese medicine is prepared from the following traditional Chinese medicinal materials in parts by weight: 5-13 parts of incarvillea younghustandii sprague, 4-8 parts of taibai-gense, 4-8 parts of cinnamomum wilsonii, 4-8 parts of deer-horn glue, 5-13 parts of asarum wulingense, 5-13 parts of smilax nipponica, 4-8 parts of tsinling larkspur root, 4-8 parts of scaposum var. vaginatum, 5-13 parts of flavescent supplejack herb, 4-8 parts of gordon euryale leaves and 4-8 parts of licorice root, and the medicinal materials are combined to achieve the effects of tonifying kidneys, promoting blood circulation, warming channel and expelling cold. The traditional Chinese medicine closely focuses on the pathogenesis of hypomenorrhea due to kidney deficiency and cold in blood after artificial abortion operation, and can be used for remarkably improving the menstruation condition and increasing the thickness of endometrium.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine for the treatment of artificial abortion hypomenorrhea.
Background technology
Hypomenorrhea refers to that menstrual cycle is normal, and menstrual blood volume obviously reduces, or the deficiency of time 2d that passes through, even drop and clean person.The hypomenorrhea of artificial abortion, close relationship is had with artificial abortion, show as the past menstrual blood volume normal more, artificial abortion menstrual cycle rule, but menstrual blood volume obviously reduces, time shorten of passing through, notably menstruation drop is namely clean, accompany or do not accompany dysmenorrhea, soreness of the waist and knees, the symptoms such as lower abdomen pain.In recent years, along with artificial abortion is as the remedial measure of contraceptive failure while being widely adopted, its postoperative concern causing the problem of hypomenorrhea also more and more to cause people.Hypomenorrhea, without medical treatment, can develop into amenorrhea, infertile, or the adverse consequences such as pregnant rear miscarriage, had a strong impact on patient's physical and mental health even family stablize.
Current Western medicine there is no effective Therapeutic Method, therefore, finds a comparatively effective Therapeutic Method and has positive clinical meaning and social meaning.
Summary of the invention
Technical problem to be solved by this invention avoids the weak point existing for above-mentioned prior art, provides a kind of Chinese medicine for the treatment of artificial abortion hypomenorrhea.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine for artificial abortion hypomenorrhea, be made up of the Chinese medicine of following weight portion:
Tibet Herba Incarvilleae sinensis 5-13 part, Rhizoma Pedicularis Davidii 4-8 part, osmanthus, river 4-8 part, Colla cornus cervi 4-8 part, Herba seu Radix Metaplexis hemsleyanae 5-13 part, Radix Schisandrae Micranthae 5-13 part, Radix Delphinii Giraldii 4-8 part, black seven 4-8 parts, flavescent supplejack herb 5-13 part, Folium Euryales 4-8 part, Radix Glycyrrhizae 4-8 part.
Preferably, the Chinese medicine of above-mentioned treatment artificial abortion hypomenorrhea, is made up of the Chinese medicine of following weight portion:
Tibet Herba Incarvilleae sinensis 7-11 part, Rhizoma Pedicularis Davidii 5-7 part, osmanthus, river 5-7 part, Colla cornus cervi 5-7 part, Herba seu Radix Metaplexis hemsleyanae 7-11 part, Radix Schisandrae Micranthae 7-11 part, Radix Delphinii Giraldii 5-7 part, black seven 5-7 parts, flavescent supplejack herb 7-11 part, Folium Euryales 5-7 part, Radix Glycyrrhizae 5-7 part.
Preferred, the Chinese medicine of above-mentioned treatment artificial abortion hypomenorrhea, is made up of the Chinese medicine of following weight portion:
Tibet Herba Incarvilleae sinensis 9 parts, Rhizoma Pedicularis Davidii 6 parts, 6 parts, osmanthus, river, Colla cornus cervi 6 parts, Folium Euryales 9 parts, Radix Schisandrae Micranthae 9 parts, Radix Delphinii Giraldii 6 parts, 76 parts, ink, flavescent supplejack herb 9 parts, Herba seu Radix Metaplexis hemsleyanae 6 parts, 6 parts, Radix Glycyrrhizae.
The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.
The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.
The indication of Chinese medicine of the present invention: be used for the treatment of blood-cold type artificial abortion hypomenorrhea of suffering from a deficiency of the kidney.
The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.
In Chinese medicine composition of the present invention,
Tibet Herba Incarvilleae sinensis another name Herba Incarvilleae sinensis, for Bignoniaceae plant hides root and the seed of POLO flower IncaruilleayounghusbandiiSprague..Sweet in the mouth; Light; Warm in nature.Function cures mainly benefiting QI and nourishing blood.Main prolonged illness is weak; Puerperal, breast was few; Dizzy; Anemia.
Rhizoma Pedicularis Davidii another name david woodbetony rhizome, black Radix Panacis Quinquefolii.For the rhizome of goatweed David Radix seu Herba Pedicularis, rough Radix seu Herba Pedicularis, Deng Shi Radix seu Herba Pedicularis, Radix seu Herba Pedicularis attractive in appearance etc.Sweet micro-hardship, temperature.Enriching yin and nourishing kidney, invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach.Control physical weakness, osteopyrexia and fever of suffering from a deficiency of the kidney, arthralgia, anorexia.
Osmanthus, river another name Cortex Cinnamomi skin, Cortex cinnamomi japonici (Ramulus Cinnamomi), derive from Lauraceae cinnamon cinnamomum argenteum Gamble (river Cortex cinnamomi japonici (Ramulus Cinnamomi)) CinnamomumargenteumGamble and Cortex Cinnamomi Tamalae tree CinnamomumtamalaNeesetEberm., acrid in the mouth, sweet, warm in nature.Function dispelling cold by warming the meridian, promoting flow of QI and blood, pain relieving.For being affected by the cold, stomach abdomen cold type of pain, dysmenorrhea, Fengshi Guanjie pain; Traumatic injury is controlled in external, fracture.
Colla cornus cervi is that Cornu Cervi is endured through decocting, the concentrated solid gum made.Sweet in the mouth, salty, warm in nature.Return kidney, Liver Channel.Function temperature compensation Liver and kidney, beneficial intensive culture blood.For sexual impotence spermatorrhea, the acid of waist knee joint is cold, asthenia weakness and emaciation, metrostaxis, and hematuria of having blood in stool, carbuncle of yin nature swells and ache.
Radix Schisandrae Micranthae is the root of Magnoliacea plant little Hua Fructus Schisandrae Chinensis.Taste temperature, property is puckery.Function promoting flow of qi by warming channel, stomach invigorating dampness removing.Dispelling the wind and dampness pathogens, traumatic injury, stomachache, menoxenia, nephritis.
Herba seu Radix Metaplexis hemsleyanae another name dish Hemsleya sphaerocarpa Kuang et A. M. Lu, interwined dragon grass, TUXIXIN.For the root of aristolochiaceae plant Five Ridges Herba Asari AsarumwulingenseC.F.Liang, rhizome or herb.Acrid in the mouth; Warm in nature. return lung; Stomach warp.Function dispelling cold by warming the meridian; Relieving cough and resolving phlegm; Reducing swelling and alleviating pain.Main stomachache; Cough with asthma; Traumatic injury; Scald; Venom; Toothache is controlled containing coughing.
Radix Delphinii Giraldii is the root of ranunculaceae plant MAOGENG Herba delphinii grandiflori DelphiniumhonanenseW.T.Wangvar.piliferumW.T.Wang.Feeble QI, acrid in the mouth, hardship, warm in nature.Return kidney; Spleen channel.Function blood circulation promoting and blood stasis dispelling; Dispersing cold for relieving pain.The headache that main stagnation of blood stasis or congealing cold with blood stasis cause; Lumbago and backache; Stomachache; Impairment caused by overstrain pain.
Ink seven another name Radix Aconiti Vaginatis, cold water bits, blood are loose seven, LONGHU son, Tu Shalian, YIKOUXUE, only ERQI, the tender tips of bamboo shoot seven, be the root of ranunculaceae plant scape monkshood root AconitumscaposumFranch. or poly-leaf Roripa Aconitum carmichjaelii Debx. AconitumscaposumFranch.var.vaginatum (Priz.) Rapaics [A.vaginatumPritz.].Acrid in the mouth; Bitter; Warm in nature.Function promoting blood flow to regulate menstruation; Eliminating stasis to stop pain.Main menoxenia; Traumatic injury harm; Fracture pain; Rheumatic arthralgia; Stomachache; Innominate toxic swelling.
Flavescent supplejack herb calls large duck Tripterygium wilfordii, Radix seu Caulis Berchemiae Hypochrysae, Shi Manteng, great Ye hesperidium.For Rhamnaceae plant Huang back of the body Radix Berchemiae Giraldianae Berchemiaflavescens(Wall.) Brongn. ［ ZizyphusflavescensWall.; BerchemiahypochrysaSchneid. ］ root, stem.Bitter in the mouth; Pungent; Cool in nature.Function heat clearing away; Pain relieving; Promoting blood flow to regulate menstruation.Main chest and abdomen swelling and pain; Dysentery; Leukorrhagia; Traumatic injury; Bones and muscles pain; Metrorrhagia; Menoxenia.
Folium Euryales another name Caput Gallus domesticus dish, Ci Heye.For the leaf of nymphaeaceae plant Gorgon euryale EuryaleferoxSalisb..Bitter in the mouth; Pungent; Property is put down.Return liver; Kidney channel.Function promoting flow of QI and blood; Hemostasis by removing blood stasis.Main haematemesis; Have blood in stool; Women's retention of placenta in puerperal.
Radix Glycyrrhizae is sweet, flat.GUIXIN, lung, spleen, stomach warp.Function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Hypomenorrhea Chinese medical book has title " a small amount of menses and menstruating unsmoothly ", " few through water ", " very few through measuring ".The kidney being the origin of congenital constitution, and married woman take blood as this, and the physiology of women led by kidney and blood.The pathological changes of kidney and blood must cause menstrual disorders, suffers from a deficiency of the kidney and all can affect the situation of menstruation with blood stasis.Kidney essense energy activating QI hemopoietic, if kidney essense plaque is weary, through insufficiency of blood, blood deficiency is appointed in punching, and the sea of blood by Man Eryi, can not be sent out as menstrual disorders.Blood flow is not smooth or stagnate, and disturbance of blood circulation also can cause menopathy.From traditional Chinese medical science viewpoint, artificial abortion also takes it by force as underdone foxtail millet, inevitably will inevitably damage uterus." Plain Questions strange sick opinion " proposes " collaterals of the uterus person, lies in kidney ", and uterus and kidney have and indirectly belong to network relation, therefore uterus is impaired also will inevitably damage kidney qi, consumes essence of being impairment of the kidney.' deficiency of kidney-essence, no resource of generating and transforming QI and blood, causes vessels of the uterus inanition, and menoxenia due to insufficiency of CHONG meridian is consequently suffered from a deficiency of the kidney then less through row amount, and gas is weak, and it is slow that gas is weak, insufficiency of blood then circulates, and the stasis of blood is stagnant smooth, and sending out is hypomenorrhea.In addition, artificial abortion system negative pressure suction nozzle mechanicalness turnover uterine cavity, must cause the damage in various degree of local organization and venation, so that blood stasis, and the blood stasis of blood is stagnant not smooth, sends out as hypomenorrhea.In addition, after artificial abortion, cold-evil is experienced, or eating cold and uncooked food excessively, cold-evil lies prostrate and appoints in punching, and blood is for cold stagnant, and run not smooth, sea of blood spill-over is few, causes through row amount few.Therefore, cold in blood of suffering from a deficiency of the kidney is the Important cause of disease pathogenesis of artificial abortion hypomenorrhea clinically, and treatment is taken in invigorating kidney, promoting blood circulation, dispelling cold by warming the meridian.
Chinese medicine composition of the present invention, its prescription mechanism is as follows:
Monarch drug: Tibet Herba Incarvilleae sinensis merit with kidney-replenishing, replenishing QI and blood.
Ministerial drug: Rhizoma Pedicularis Davidii merit is with enriching yin and nourishing kidney; Osmanthus, river merit is with dispelling cold by warming the meridian;
Adjuvant drug: Colla cornus cervi merit with liver and kidney tonifying, beneficial intensive culture blood; Herba seu Radix Metaplexis hemsleyanae, Radix Schisandrae Micranthae merit are with dispelling cold by warming the meridian, and circulation of qi promoting is active; Radix Delphinii Giraldii merit is with nourishing blood for regulating menstruation; Ink seven, flavescent supplejack herb merit are with promoting blood flow to regulate menstruation; Folium Euryales merit is with circulation of qi promoting regulating menstruation.
Make medicine: Radix Glycyrrhizae merit is with coordinating the actions of various ingredients in a prescription.
We's compatibility is reasonable, and all medicines share negative and positive and adjust, and logical benefit dual-purpose, plays invigorating kidney, promoting blood circulation, the effect of dispelling cold by warming the meridian altogether.The artificial abortion hypomenorrhea that links closely is suffered from a deficiency of the kidney the pathogenesis of syndrome of blood-cold, obviously can improve menstruation, increases endometrium thickness.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Tibet Herba Incarvilleae sinensis 9g, Rhizoma Pedicularis Davidii 6g, osmanthus, river 6g, Colla cornus cervi 6g, Herba seu Radix Metaplexis hemsleyanae 9g, Radix Schisandrae Micranthae 9g, Radix Delphinii Giraldii 6g, black seven 6g, flavescent supplejack herb 9g, Folium Euryales 6g, Radix Glycyrrhizae 6g.
Embodiment 2
Treat a Chinese medicine for artificial abortion hypomenorrhea, each crude drug weight proportion is as follows:
Tibet Herba Incarvilleae sinensis 7g, Rhizoma Pedicularis Davidii 5g, osmanthus, river 5g, Colla cornus cervi 5g, Herba seu Radix Metaplexis hemsleyanae 7g, Radix Schisandrae Micranthae 7g, Radix Delphinii Giraldii 5g, black seven 5g, flavescent supplejack herb 7g, Folium Euryales 5g, Radix Glycyrrhizae 5g.
Embodiment 3
Treat a Chinese medicine for artificial abortion hypomenorrhea, each crude drug weight proportion is as follows:
Tibet Herba Incarvilleae sinensis 11g, Rhizoma Pedicularis Davidii 7g, osmanthus, river 7g, Colla cornus cervi 7g, Herba seu Radix Metaplexis hemsleyanae 11g, Radix Schisandrae Micranthae 11g, Radix Delphinii Giraldii 7g, black seven 7g, flavescent supplejack herb 11g, Folium Euryales 7g, Radix Glycyrrhizae 7g.
Embodiment 4
Treat a Chinese medicine for artificial abortion hypomenorrhea, each crude drug weight proportion is as follows:
Tibet Herba Incarvilleae sinensis 13g, Rhizoma Pedicularis Davidii 8g, osmanthus, river 8g, Colla cornus cervi 8g, Herba seu Radix Metaplexis hemsleyanae 13g, Radix Schisandrae Micranthae 13g, Radix Delphinii Giraldii 8g, black seven 8g, flavescent supplejack herb 13g, Folium Euryales 8g, Radix Glycyrrhizae 8g.
Embodiment 5
Treat a Chinese medicine for artificial abortion hypomenorrhea, each crude drug weight proportion is as follows:
Tibet Herba Incarvilleae sinensis 5g, Rhizoma Pedicularis Davidii 4g, osmanthus, river 4g, Colla cornus cervi 4g, Herba seu Radix Metaplexis hemsleyanae 5g, Radix Schisandrae Micranthae 5g, Radix Delphinii Giraldii 4g, black seven 4g, flavescent supplejack herb 5g, Folium Euryales 4g, Radix Glycyrrhizae 4g.
Carried out clinical pharrnacokinetics test to Chinese medicine composition of the present invention, Details as Follows:
1 clinical data
1.1 physical data
Choose and meet the diagnosis of artificial abortion hypomenorrhea, and menstrual cycle is in 28-30d person 60 example, is divided into 2 groups at random.Treatment group 3O example, the mean age (26.28 ± 2.16) year, the course of disease (8.23 ± 1.21) moon, abortion times (2.45 ± 1.06) is secondary; Matched group 30 example, the mean age (27.08 ± 3.06) year, the course of disease (8.08 ± 1.34) moon, abortion times (2.31 ± 1.23) is secondary.Age of 2 groups of patients, the course of disease, abortion times are through the statistics difference (P>0.05) that compares that there are no significant.
1.2 diagnostic criteria
Menstrual cycle is normal, and menstrual blood volume obviously reduces, or the deficiency of time 2 days of passing through, even drop and clean person, it is generally acknowledged Hypomenorrhea in 20mL be hypomenorrhea.
2 methods
2.1 Therapeutic Method
Treatment group: the Chinese medicine giving the embodiment of the present invention 1.Except Colla cornus cervi, other medicines decocting extracting juice 300mL, respectively at every day sooner or later twice decoction being taken warmly (rear yellow wine smashed to pieces by Colla cornus cervi, or boiled water dissolve after take, every day 2 times, each 3g), every day 1 dose, taking continuously 3 weeks is a course for the treatment of.
Matched group: adopt artificial cycle and estrogen and progestogen sequential therapy, start oral progynova 1mg/ time, every day 1 time, serve on 21d in menstrual cycle 5d, the 11d that certainly takes medicine starts to add use progesterone capsule 100mg/ time, every day 1 time, serve on lOd.Serveing on 3 cycles was 1 course for the treatment of.
2.2 observation index
The change of observation menstrual blood volume, pass through time and endometrium thickness (the front menstrual cycle 21d for the treatment of and menstrual cycle 21d capable ultrasound diagnosis record endometrium thickness after treating 3 end cycles).
3 criterions of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
With reference to " new Chinese medicine guideline of clinical investigations " and " Chinese medical disease Standardization of diagnosis and curative effect ".Cure: after drug withdrawal, menstrual blood volume returns to previously menstrual blood volume, menstrual period 3 ~ 7d; Effective: after drug withdrawal, menstrual blood volume obviously increases, reach more than 2/3 of previously menstrual blood volume, menstrual period 3 ~ 7d; Take a turn for the better: after drug withdrawal, menstrual blood volume increases, reach 1/3 ~ 2/3 of previously menstrual blood volume, menstrual period 2 ~ 7d; Invalid: menstrual blood volume without increase, or is still less than 1/3 of previously menstrual blood volume, or menstrual period <2d.
3.2 therapeutic outcome
3.2.12 group patient comparitive study
Treatment group 30 example, cures 14 examples (46.67%), effective 9 examples (30.O0%), 5 examples that take a turn for the better (16.67%), invalid 2 examples (6.67%), total effective rate 93.33%.
Matched group 30 example, cures 5 examples (16.67%), effective 9 examples (30.O0%), 7 examples that take a turn for the better (23.33%), no effect 9 (30.O0%), total effective rate 70.O0%.Treatment group total effective rate is better than matched group (P<O.05).
3.2.22 before and after group treatment, the time of passing through compares
After 2 groups of treatments, the time of passing through all comparatively treats front obviously prolongation (P<0.05), and after 2 groups of patient treatments, the time of passing through compares through statistics, there was no significant difference (P>0.O5).In table 1.
Before and after the treatment of table 12 group, the time of passing through compares (x ± s)
| Group | n | Before treatment | After treatment |
| Treatment group | 30 | 2.06±0.13 | 5.33±0.86* |
| Matched group | 30 | 2.08±0.18 | 5.04±0.95* |
Note: * compares with before treatment, P<0.05.
3.2.32 before and after group treatment, endometrium thickness compares
After 2 groups of treatments, endometrium thickness obviously thickens (P<0.05) before all comparatively treating, and is thicker than matched group (P<0.05) in treatment group.In table 2.
Before and after the treatment of table 22 group, endometrium thickness compares (x ± s)
| Group | n | Before treatment/mm | After treatment/mm |
| Treatment group | 30 | 4.63±0.85 | 9.32±1.51*# |
| Matched group | 30 | 4.59±0.75 | 7.12±1.62* |
Note: compare with before treatment, * P<O.05; Compare with matched group, #P<O.05.
Claims (3)
1. treat a Chinese medicine for artificial abortion hypomenorrhea, be made up of the Chinese medicine of following weight portion:
Tibet Herba Incarvilleae sinensis 5-13 part, Rhizoma Pedicularis Davidii 4-8 part, osmanthus, river 4-8 part, Colla cornus cervi 4-8 part, Herba seu Radix Metaplexis hemsleyanae 5-13 part, Radix Schisandrae Micranthae 5-13 part, Radix Delphinii Giraldii 4-8 part, black seven 4-8 parts, flavescent supplejack herb 5-13 part, Folium Euryales 4-8 part, Radix Glycyrrhizae 4-8 part.
2. the Chinese medicine for the treatment of artificial abortion hypomenorrhea according to claim 1, is characterized in that, be made up of the Chinese medicine of following weight portion:
Tibet Herba Incarvilleae sinensis 7-11 part, Rhizoma Pedicularis Davidii 5-7 part, osmanthus, river 5-7 part, Colla cornus cervi 5-7 part, Herba seu Radix Metaplexis hemsleyanae 7-11 part, Radix Schisandrae Micranthae 7-11 part, Radix Delphinii Giraldii 5-7 part, black seven 5-7 parts, flavescent supplejack herb 7-11 part, Folium Euryales 5-7 part, Radix Glycyrrhizae 5-7 part.
3. the Chinese medicine for the treatment of artificial abortion hypomenorrhea according to claim 3, is characterized in that, be made up of the Chinese medicine of following weight portion:
Tibet Herba Incarvilleae sinensis 9 parts, Rhizoma Pedicularis Davidii 6 parts, 6 parts, osmanthus, river, Colla cornus cervi 6 parts, Herba seu Radix Metaplexis hemsleyanae 9 parts, Radix Schisandrae Micranthae 9 parts, Radix Delphinii Giraldii 6 parts, 76 parts, ink, flavescent supplejack herb 9 parts, Folium Euryales 6 parts, 6 parts, Radix Glycyrrhizae.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1748760A (en) * | 2004-09-15 | 2006-03-22 | 王保安 | Medicine for treating female menstrual disorder (stagnancy of qi and blood stasis) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1748760A (en) * | 2004-09-15 | 2006-03-22 | 王保安 | Medicine for treating female menstrual disorder (stagnancy of qi and blood stasis) |
Non-Patent Citations (1)
| Title |
|---|
| 陈靓芬等: "补肾活血法治疗人工流产术后月经过少疗效观察", 《云南中医中药杂志》 * |
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