CN105168964A - Traditional Chinese medicinal composition for treating keratitis - Google Patents

Abstract

The invention provides a traditional Chinese medicinal composition for treating keratitis. The traditional Chinese medicinal composition is prepared from the following oral administration medicines: eriocaulon buergerianum, equisetum hiemale, fructus tribuli, arctium lappa, ophiopogon japonica, dendrobe, bidens pilosa, adenophora stricta, flatstem milkvetch seed, Chinese angelica, bat dung, abrotani herba, periostracum cicada, medlar, radix rehmanniae recen, radix astragali, pyrrosia lingua and babysbreath, and external application medicines: chelidonium majus, Chinese amphibious knotweed rhizome and alternanthera philoxeroides. According to the traditional Chinese medicinal composition disclosed by the invention, by adopting the overall treatment concept of traditional Chinese medicine, the advantage that root causes can be addressed by the traditional Chinese medicine; by internal administration with external application, the efficacy of clearing away heat and toxic materials and removing nebula for improving eyesight is realized, and viral keratitis is thoroughly cured.

Description

A kind of Chinese medicine composition for the treatment of keratitis

Technical field

The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of keratitis.

Background technology

The Corneal inflammation that herpes simplex infections causes is called herpes simplex keratitis (Herpessimplexkeratitis, HSK).HSV-1 keratitis is common, serious keratopathy, occupies the first place of keratopathy sickness rate and causes of blindness.Herpes simplex keratitis is at present the most serious common keratopathy, has in recent years and obviously rises and aggravation trend, and due to the extensive use of antibiotic and corticosteroid, its sickness rate is on the rise.

This sick similar traditional Chinese medical science " dendritic keratitis " " keratomalacia " " interstitial keratitis ", is because of diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, holds transconversion into heat fire under the arm, and on blackening eyeball, raw tiny punctate keratitis is with puckery pain, photophobia, the oculopathy of shedding tears, and deeply development, can form cicatrix cataracta, make eyesight impaired.This disease often has obvious irritated eyes, as photophobia, sheds tears, aches.Viral keratitis, the course of disease is often longer.Along with the progress of the course of disease, often can occur together uveitis, even occurs that iridocyclitis, hypopyon are swollen, or secondary glaucoma, is one of comparatively common diseases causing blindness.

This disease is the serious harm visual function because of recurrent exerbation often, the clinical medicine that there is no effective Control in recurring, thus becomes a kind of global important causes of blindness.Current tcm clinical practice medical treatment primary disease many employings therapy of combining Chinese and Western medicine, mostly be external Western medicine eye drop or eye ointment: 1% ribavirin (virazole), 0.1% acyclovir, 0.05% ancitabine, 1% trifluridine, 0.1% ganciclovir etc., then add extract oral.Good curative effect can be obtained in general.But antiviral drugs external corneal has certain toxicity, the caused corneal epithelium had damages, and causes cornea diffusivity painted, and the corneal ulcer that makes had is difficult to healing.And simple Chinese medicine can not get good curative effect.And do not treat the Chinese medicine of herpes zoster ophthalmicus and herpes simplex keratitis determined curative effect at present on the market, therefore, the Chinese medicine of the better efficacy for the treatment of herpes zoster and herpes simplex keratitis is the problem needing solution at present badly.

Summary of the invention

The object of the invention is by tcm therapy, adopts traditional Chinese medical science wholistic therapy idea, plays the advantage that the traditional Chinese medical science is effected a permanent cure, by combining oral external application, and heat-clearing and toxic substances removing, removing nebula to improve visual acuity, fundamentally Cure Viruses keratitis.

Technical solution of the present invention is, a kind of Chinese medicine composition for the treatment of keratitis, by weight, comprises the crude drug of following component:

First group: Flos Eriocauli 4-5 part, Herba Equiseti Hiemalis 3-9 part, Fructus Tribuli 6-9 part, Fructus Arctii 6-12 part, Radix Ophiopogonis 6-12 part, Herba Dendrobii 6-12 part, Herba Bidentis Bipinnatae 10-20 part, Radix Adenophorae (Radix Glehniae) 10-15 part, Semen Astragali Complanati 9-15 part, Radix Angelicae Sinensis 10-20 part, Faeces Vespertilionis 5-9 part, Herba Artemisiae Annuae 10-15 part, Periostracum Cicadae 5-10 part, Fructus Lycii 10-20 part, Radix Rehmanniae 10-15 part, Radix Astragali 10-15 part, Folium Pyrrosiae 6-9 part, Caulis et folium pavettae hongkongensis 5-10 part;

Second group: Herba Chelidonii 5-10 part, Rhizoma Polygoni sinensis 5-10 part, Radix Alternantherae philoxeroidis 5-10 part.

Method of preparation and use: after first group of raw material of Chinese medicine medicine is soaked half an hour, decoct 15 minutes, every day, potion, took at twice.

Cleaned by second group of raw material of Chinese medicine medicine, spread on and suffer from eye after mashing, if eyes are ill, also alternately can apply eye for convenience of life, cover by 10*12 ㎝ size cotton pad, immobilization with adhesive tape, every day changes dressings once.

The traditional Chinese medical science thinks no matter be that diseases caused by exogenous pathogenic factor six climate exopathogens, internal damage by the excessive seven emotions, drinking and eating irregularly all can cause primary disease, but sees exopathogen at most.Cornea belongs to wind wheel, planted agent in liver, the relation and spleen and liver counteract each other, The liver and the kidney have a common source, therefore primary disease and liver,spleen,kidney in close relations.From course of disease primary disease in early days based on the heresy of wind heat or wind and cold, belong to exterior syndrome; Mid-term or obstinate phase are based on dampness-heat in the liver and gallbladder or insufficiency of the spleen leading to overabundance of dampness; Also there is the performance of deficiency complicated with excess in later stage.During treatment, not only removing damp-heat, improving eyesight removing toxic substances, also wants removing obstruction in the collateral to relieve pain, benefiting QI and nourishing blood.Chinese medicine composition of the present invention, through meticulous prescription, for oral administration add external application and share, and evident in efficacy, the pharmacological action of each crude drug is as follows:

Flos Eriocauli---[nature and flavor] are pungent, sweet, flat.[return through] returns liver, lung meridian.[function cures mainly] dispelling wind and heat pathogens, improving eyesight, nebula removing.For wind heat conjunctival congestion, swell and ache photophobia, nebula of looking unfamiliar film, headache due to pathogenic wind-heat.

Herba Equiseti Hiemalis---[nature and flavor] are sweet, bitter, flat.[return through] returns lung, Liver Channel.[function cures mainly] to be fallen apart wind heat, is moved back corneal nebula.For wind heat conjunctival congestion, epiphora induced by wind, the raw nebula of order.

Fructus Tribuli---[nature and flavor] are pungent, bitter, tepor; Slightly poisonous.[return through] returns Liver Channel.[function cures mainly] suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.

Fructus Arctii---[nature and flavor] are pungent, bitter, cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.For anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, mumps erysipelas, carbuncle sore tumefacting virus.

Herba Dendrobii---[nature and flavor] are sweet, are slightly cold.[return through] returns stomach, kidney channel.[function cures mainly] reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.

Radix Ophiopogonis---[nature and flavor] are sweet, and micro-hardship, is slightly cold.[return through] GUIXIN, lung, stomach warp.[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.

Herba Bidentis Bipinnatae---[nature and flavor] bitter in the mouth; Cold nature [function cures mainly] heat-clearing and toxic substances removing; Expelling wind and removing dampness; Promoting blood circulation and detumescence.Main throat; Swell and ache; Have loose bowels; Dysentery; Jaundice; Intestinal carbuncle; Furuncle swelling toxin; Serpentis is early bitten; Rheumatic arthralgia; Traumatic injury

Radix Adenophorae (Radix Glehniae)---[nature and flavor] sweet in the mouth; Micro-hardship; Cold nature [return through] returns lung; Stomach is through [function cures mainly] replenishing YIN and removing heat; Moistening the lung and resolving phlegm; Reinforcing stomach reg fluid.Main deficiency of YIN chronic cough; Consumptive disease is coughed expectorant blood; Cough caused by dryness expectorant is few; Deficiency-heat sore throat; Tianjin wound is thirsty.

Semen Astragali Complanati---[nature and flavor] are sweet, temperature.[return through] returns liver, kidney channel.[function cures mainly] temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, improving eyesight.For lumbago due to renal deficiency, seminal emission premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizzy blurred vision.

Radix Angelicae Sinensis---[nature and flavor] temperature, sweet, pungent.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Radix Angelicae Sinensis can improve hypercoagulability in body, and adjustment blood lipid metabolism, reduces cholesterol.

Faeces Vespertilionis---[nature and flavor] are pungent, cold.[return through] enters Liver Channel.[function cures mainly] clearing away heat to improve acuity of vision, promoting blood circulation to remove stagnancy.For nyctalopia, cataract, corneal nebula.

Herba Artemisiae Annuae---[nature and flavor] bitter, acrid, cold.[return through] returns liver, gallbladder meridian.[function cures mainly] clearing away summer-heat, except steaming, preventing the attack (or recurrence) of malaria.For pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.Enter decoct should after under.

Periostracum Cicadae---[nature and flavor] are sweet, cold.[return through] returns lung, Liver Channel.[function cures mainly] falls apart wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.

Radix Rehmanniae---[return through] GUIXIN, liver, kidney channel.[function cures mainly] Radix Rehmanniae: clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.

Fructus Lycii---[nature and flavor] are sweet, flat.[return through] returns liver, kidney channel.[function cures mainly] nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.

The Radix Astragali---[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.

Folium Pyrrosiae---[nature and flavor] are sweet, bitter, are slightly cold.[return through] returns lung, urinary bladder channel.[function cures mainly] inducing diuresis for treating stranguria syndrome, clearing away heat to stop bleeding.For pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop, spits blood, epistaxis, hematuria, metrorrhagia, dyspnea and cough due to lung-heat.

The lightly seasoned micro-hardship of Caulis et folium pavettae hongkongensis-[nature and flavor], property is put down.[function cures mainly] clearing away heat to improve acuity of vision, moves back nebula, detumescence.Control corneal leukoma, conjunctival congestion and swelling pain.

Herba Chelidonii---[nature and flavor] are bitter, cool.Poisonous.[function cures mainly] heat-clearing and toxic substances removing, pain relieving, cough-relieving.For gastritis, gastric ulcer, stomachache, enteritis, dysentery, jaundice, chronic tracheitis, pertussis; Paddy-field dermatitis is controlled in external, insect-bite.

Rhizoma Polygoni sinensis---[nature and flavor] micro-hardship, puckery, flat.Slightly poisonous.[function cures mainly] heat-clearing and toxic substances removing, astringing to arrest diarrhea, promoting blood circulation and stopping pain.For bacillary dysentery, gastroenteritis, traumatic injury, traumatic hemorrhage.

Radix Alternantherae philoxeroidis---[nature and flavor] " root: bitter, cold; Stem and leaf: micro-sweet, cold." [function cures mainly] heat clearing away, removing heat from blood, diuresis, removing toxic substances.Control measles, encephalitis B, pulmonary tuberculosis hemoptysis, stranguria with turbid discharge, herpes zoster, furuncle furuncle, venom.

Abundant raw material of the present invention, cheap, all medicines share the effect with removing dampness and detoxicating, clearing away heat to improve acuity of vision, removing obstruction in the collateral to relieve pain, benefiting QI and nourishing blood, be used for the treatment of herpes zoster ophthalmicus and herpes simplex keratitis, good effect, and drug safety, have no side effect, relapse rate is low, is to treat the innovation on herpes zoster and herpes simplex keratitis medicine.

Detailed description of the invention

Below by embodiment and test example, the invention will be further described.But the present invention is not limited to described in embodiment, those of ordinary skill in the art do some amendment, all in scope.

Embodiment 1. 1 kinds treats the Chinese medicine composition of keratitis, comprises the crude drug of following component:

First group: Flos Eriocauli 4 grams, Herba Equiseti Hiemalis 3 grams, Fructus Tribuli 6 grams, Fructus Arctii 6 grams, Radix Ophiopogonis 6 grams, Herba Dendrobii 6 grams, Herba Bidentis Bipinnatae 10 grams, Radix Adenophorae (Radix Glehniae) 10 grams, Semen Astragali Complanati 9 grams, Radix Angelicae Sinensis 10 grams, Faeces Vespertilionis 5 grams, Herba Artemisiae Annuae 10 grams, Periostracum Cicadae 5 grams, Fructus Lycii 10 grams, Radix Rehmanniae 10 grams, the Radix Astragali 10 grams, Folium Pyrrosiae 6 grams, Caulis et folium pavettae hongkongensis 5 grams;

Second group: Herba Chelidonii 5 grams, Rhizoma Polygoni sinensis 5 grams, Radix Alternantherae philoxeroidis 5 grams.

Method of preparation and use: after first group of raw material of Chinese medicine medicine is soaked half an hour, decoct 15 minutes, every day, potion, took at twice.

Cleaned by second group of raw material of Chinese medicine medicine, spread on and suffer from eye after mashing, if eyes are ill, also alternately can apply eye for convenience of life, cover by 10*12 ㎝ size cotton pad, immobilization with adhesive tape, every day changes dressings once.

Embodiment 2. 1 kinds treats the Chinese medicine composition of keratitis, comprises the crude drug of following component:

First group: Flos Eriocauli 5 grams, Herba Equiseti Hiemalis 9 grams, Fructus Tribuli 9 grams, Fructus Arctii 12 grams, Radix Ophiopogonis 12 grams, Herba Dendrobii 12 grams, Herba Bidentis Bipinnatae 20 grams, Radix Adenophorae (Radix Glehniae) 15 grams, Semen Astragali Complanati 15 grams, Radix Angelicae Sinensis 20 grams, Faeces Vespertilionis 9 grams, Herba Artemisiae Annuae 15 grams, Periostracum Cicadae 10 grams, Fructus Lycii 20 grams, Radix Rehmanniae 15 grams, the Radix Astragali 15 grams, Folium Pyrrosiae 9 grams, Caulis et folium pavettae hongkongensis 10 grams;

Second group: Herba Chelidonii 10 grams, Rhizoma Polygoni sinensis 10 grams, Radix Alternantherae philoxeroidis 10 grams.

Method of preparation and use is with embodiment one

Embodiment 3. 1 kinds treats the Chinese medicine composition of keratitis, comprises the crude drug of following component:

First group: Flos Eriocauli 5 grams, Herba Equiseti Hiemalis 6 grams, Fructus Tribuli 8 grams, Fructus Arctii 10 grams, Radix Ophiopogonis 10 grams, Herba Dendrobii 10 grams, Herba Bidentis Bipinnatae 15 grams, Radix Adenophorae (Radix Glehniae) 12 grams, Semen Astragali Complanati 12 grams, Radix Angelicae Sinensis 15 grams, Faeces Vespertilionis 7 grams, Herba Artemisiae Annuae 12 grams, Periostracum Cicadae 8 grams, Fructus Lycii 15 grams, Radix Rehmanniae 12 grams, the Radix Astragali 12 grams, Folium Pyrrosiae 7 grams, Caulis et folium pavettae hongkongensis 6 grams;

Second group: Herba Chelidonii 7 grams, Rhizoma Polygoni sinensis 8 grams, Radix Alternantherae philoxeroidis 8 grams.

Method of preparation and use is with embodiment one

Embodiment 4. 1 kinds treats the Chinese medicine composition of keratitis, comprises the crude drug of following component:

First group: Flos Eriocauli 4 grams, Herba Equiseti Hiemalis 4 grams, Fructus Tribuli 7 grams, Fructus Arctii 8 grams, Radix Ophiopogonis 8 grams, Herba Dendrobii 8 grams, Herba Bidentis Bipinnatae 16 grams, Radix Adenophorae (Radix Glehniae) 13 grams, Semen Astragali Complanati 13 grams, Radix Angelicae Sinensis 18 grams, Faeces Vespertilionis 9 grams, Herba Artemisiae Annuae 11 grams, Periostracum Cicadae 9 grams, Fructus Lycii 17 grams, Radix Rehmanniae 13 grams, the Radix Astragali 14 grams, Folium Pyrrosiae 8 grams, Caulis et folium pavettae hongkongensis 8 grams;

Second group: Herba Chelidonii 8 grams, Rhizoma Polygoni sinensis 8 grams, Radix Alternantherae philoxeroidis 8 grams.

Method of preparation and use is with embodiment one

Embodiment 5. 1 kinds treats the Chinese medicine composition of keratitis, comprises the crude drug of following component:

First group: Flos Eriocauli 5 grams, Herba Equiseti Hiemalis 3 grams, Fructus Tribuli 9 grams, Fructus Arctii 10 grams, Radix Ophiopogonis 10 grams, Herba Dendrobii 10 grams, Herba Bidentis Bipinnatae 10 grams, Radix Adenophorae (Radix Glehniae) 10 grams, Semen Astragali Complanati 10 grams, Radix Angelicae Sinensis 10 grams, Faeces Vespertilionis 6 grams, Herba Artemisiae Annuae 10 grams, Periostracum Cicadae 6 grams, Fructus Lycii 20 grams, Radix Rehmanniae 15 grams, the Radix Astragali 15 grams, Folium Pyrrosiae 7 grams, Caulis et folium pavettae hongkongensis 10 grams;

Second group: Herba Chelidonii 5-10 gram, Rhizoma Polygoni sinensis 5-10 gram, Radix Alternantherae philoxeroidis 5-10 gram.

Method of preparation and use is with embodiment one

The clinical observation of test example 1, treatment herpes simplex keratitis

1 clinical data

1.1 physical data

Year January in January, 2012 to 2014 is to medical patient 140 example (140) being diagnosed as herpes simplex keratitis (HSK) of my Out-patient Department, man 89, female 51,20 ~ 73 years old age, on average (39.5 ± 17.8) year, be First episode; Wherein dendritic keratitis 98 example, map shape keratitis 38 example, disciform keratitis 4 example; The shortest 1d of the course of disease, the longest 10d, average (4.2 ± 2.6) d.140 examples all meet following diagnostic criteria: (1) has obvious inducement: the medical histories such as flu, heating; (2) have obvious irritated eyes: pain, photophobia, shed tears, the irritated eyes such as blepharospasm; (3) cornea has point-like, dendroid, map shape to infiltrate or ulcer, edema, and fluorescein sodium dyeing (FC) is positive; (4) vision declines in various degree.140 examples (140) patient be divided at random treatment group 70 example (70) and with matched group 70 example (70), the distribution basic simlarity of age of two groups of patients, sex, the course of disease, sick type, has comparability.Case exclusion standard: 1. not according to regulation medication person; 2. duration of test drug withdrawal or change other antiviral drugs persons voluntarily.

1.2 Therapeutic Method

Treatment by Chinese herbs group adopts that Chinese medicine composition of the present invention is oral adds external application, every day potion.

Matched group oral indometacin 25mg and antivirus oral liquid 10mL, every day 3 times, trouble eye is dripped, every day 4 times in the treatment group ganciclovir ophthalmic gel local of 0.15%.Injectable interferon intramuscular injection, the next day 1 time. vitamin C 0.2 gram of every day three times is oral.

Further consultation after 14 days, the irritated eyes of record patient, bulbar conjunctiva ciliary congestion degree, cornea improve situation.

1.3 curative effect judging standard

There are flu, heating or specific predisposing factors in diagnostic criteria and typing [1] (1), recurrent exerbation; (2) corneal sensation is gone down, conjunctival congestion; (3) corneal opacity, in dendroid, map shape or plate-like change; (4) fluorescein corneal dyeing (+).Shallow-layer type is divided into: pathological changes is dendroid, map shape according to keratopathy form; Deep-type: pathological changes is plate-like and substrate necrotic type.

Cure: irritated eyes disappears, corneal infiltration edema disappears, and corneal ulcer heals, and fluorescein sodium is negative staining, corneal transparency or only stay nebula, and vision improves more than 2 row; Take a turn for the better: symptom and sign are obviously improved, and corneal infiltration edema alleviates; Invalid: after treatment 14d, symptom, Signs are not improved; Recurrence: eye photophobia occurs again, sheds tears, foreign body sensation, cornea has point-like, dendroid, map shape to infiltrate or ulcer, edema, fluorescence sodium stained positive.

1.4 statistical procedures

Adopt rank test, X2 inspection and exact method method.

2 results

The cure rate for the treatment of group is 85.8%, and apparently higher than 68.40% of matched group, the curative effect for the treatment of group is also obviously better than matched group, and difference all has statistical significance (P<0.05), refers to table 1.

Table 1

Group	Cure	Take a turn for the better	Invalid	Total effective rate
					Treatment by Chinese herbs group 70	60(85.7％)	9(12.9％)	1(1.4％)	98.6％
Matched group 70	50(71.4％)	13(18.6％)	7(10％)	90％

There is ocular pain after having 2 routine medications in matched group, but still can stand, and do not affect treatment; After 2 routine medications, bulbar conjunctiva ciliary congestion increases the weight of, and treatment group does not find ophthalmic uncomfortable.Two groups all do not find systemic adverse reactions.With diagnosis 1 year, treatment group 1 case relapsed, relapse rate is 1.4%; Matched group recurrence 5 example, relapse rate is 7.1%, and the relapse rate for the treatment of group is starkly lower than matched group, and difference has statistical significance (P<0.05).Explanation traditional Chinese medicine composition for treating herpes simplex keratitis of the present invention can improve cure rate.

3 discuss

Herpes simplex keratitis is dangerous maximum viral infection oculopathy in all viral keratitiss, sickness rate accounts for the first place of keratopathy, be characterized in polymorphic type, easy recurrence, there is no effective preventive means at present, treatment generally adopts antiviral drugs, hormone and immunomodulator, but all can not effective Control in recurring, when body's immunity is low, once the situations such as fatigue, flu, emotion stimulation or application corticosteroid medication that run into easily recur.How to take effective measures treatment herpes simplex keratitis and good effect, relapse rate is little, is of great significance.

The pathogenesis of viral keratitis is: the morbidity of shallow-layer is simplex virus direct infection corneal epithelial cell and propagation causes wall regeneration to come off formation epithelial defect.The morbidity of deep-type non-viral continuous proliferation, and mainly a kind of host to the immunoreation of the antigen of virus, the delayed hypersensitivity based on cellular immunization.Herpesvirus has sets up the feature of forever hiding at human body trigeminal ganglion, reaches cornea produce recurrent infection after the viral activation of hiding through axonal transport.This may be the root of primary disease recurrent exerbation.Because the problem of virus lays dormant and disease relapse is difficult to solve.

With Chinese medicine composition Comprehensive Treatment of the present invention, it is good to have the inhibitory action of viral keratitis, has the advantages such as determined curative effect, toxicity is low, untoward reaction is little, all right enhancing human body immunity power, thus reduces recurrence, and curative effect is maximized.

Claims (3)

1. treat a Chinese medicine composition for keratitis, it is characterized in that, by weight, comprise the crude drug of following component:

First group: Flos Eriocauli 4-5 part, Herba Equiseti Hiemalis 3-9 part, Fructus Tribuli 6-9 part, Fructus Arctii 6-12 part, Radix Ophiopogonis 6-12 part, Herba Dendrobii 6-12 part, Herba Bidentis Bipinnatae 10-20 part, Radix Adenophorae (Radix Glehniae) 10-15 part, Semen Astragali Complanati 9-15 part, Radix Angelicae Sinensis 10-20 part, Faeces Vespertilionis 5-9 part, Herba Artemisiae Annuae 10-15 part, Periostracum Cicadae 5-10 part, Fructus Lycii 10-20 part, Radix Rehmanniae 10-15 part, Radix Astragali 10-15 part, Folium Pyrrosiae 6-9 part, Caulis et folium pavettae hongkongensis 5-10 part;

Second group: Herba Chelidonii 5-10 part, Rhizoma Polygoni sinensis 5-10 part, Radix Alternantherae philoxeroidis 5-10 part.

2. the Chinese medicine composition for the treatment of keratitis as claimed in claim 1, is characterized in that, by weight, comprise the crude drug of following component:

First group: Flos Eriocauli 5 parts, Herba Equiseti Hiemalis 6 parts, Fructus Tribuli 8 parts, Fructus Arctii 10 parts, Radix Ophiopogonis 10 parts, Herba Dendrobii 10 parts, Herba Bidentis Bipinnatae 15 parts, Radix Adenophorae (Radix Glehniae) 12 parts, Semen Astragali Complanati 12 parts, Radix Angelicae Sinensis 15 parts, Faeces Vespertilionis 7 parts, Herba Artemisiae Annuae 12 parts, Periostracum Cicadae 8 parts, Fructus Lycii 15 parts, Radix Rehmanniae 12 parts, the Radix Astragali 12 parts, Folium Pyrrosiae 7 parts, Caulis et folium pavettae hongkongensis 6 parts;

Second group: Herba Chelidonii 7 parts, Rhizoma Polygoni sinensis 8 parts, Radix Alternantherae philoxeroidis 8 parts.

3. the Chinese medicine composition of the treatment keratitis described in claim 1 or 2, is characterized in that, first group of raw material of Chinese medicine medicine is oral medicine, and second group of raw material of Chinese medicine medicine is application compress.