CN105106374A - Medicinal composition for treating skin itch caused by pathogenic wind and preparation method thereof - Google Patents

Medicinal composition for treating skin itch caused by pathogenic wind and preparation method thereof Download PDF

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Publication number
CN105106374A
CN105106374A CN201510647744.7A CN201510647744A CN105106374A CN 105106374 A CN105106374 A CN 105106374A CN 201510647744 A CN201510647744 A CN 201510647744A CN 105106374 A CN105106374 A CN 105106374A
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China
Prior art keywords
parts
cold
ailment
exposure
skin pruritus
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Pending
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CN201510647744.7A
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Chinese (zh)
Inventor
李易春
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GUANGDONG YIMING PHARMACEUTICAL CO Ltd
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GUANGDONG YIMING PHARMACEUTICAL CO Ltd
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Priority to CN201510647744.7A priority Critical patent/CN105106374A/en
Publication of CN105106374A publication Critical patent/CN105106374A/en
Pending legal-status Critical Current

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Abstract

The invention relates to the field of pharmacy, particularly to a medicinal composition for treating skin itch caused by pathogenic wind and a preparation method thereof. The composition comprises the following components in part by weight: 6 to 8 parts of Chinese parsnip root, 2 to 4 parts of zaocys dhumnade, 6 to 8 parts of paniculate swallowwort root, 2 to 4 parts of schizonepeta, 2 to 4 parts of radix angelicae pubescentis, 2 to 4 parts of fructus kochiae, 2 to 4 parts of cortex dictamni, 2 to 4 parts of Chinese lobelia and 2 to 4 parts of cassia twig. The entire formula is complementary in gain, synergistic and remarkable in effect; moreover, the zaocys dhumnade is soaked in wine with alcohol volume ratio reaching 60 percent preferably than being unconventionally ground into powder, because the repeated experiment shows that when the zaocys dhumnade is soaked in the wine with the alcohol volume ratio reach 60 percent, and 600 to 700w ultrasonic treatment with frequency of 40KHz to 45KHz is carried out, compared with the zaocys dhumnade powder, the medicinal effect is greatly improved by virtue of further treatment, and pharmaceutical preparation of the component is facilitated.

Description

A kind ofly treat pharmaceutical composition of the caused skin pruritus of ailment said due to cold or exposure and preparation method thereof
Technical field
The present invention relates to pharmaceutical field, be specifically related to a kind ofly treat pharmaceutical composition of the caused skin pruritus of ailment said due to cold or exposure and preparation method thereof.
Background technology
Ailment said due to cold or exposure is one of tcm causa morbi.Wind is main gas in spring, and ailment said due to cold or exposure is caused a disease and is more common in spring, but all can fall ill throughout the year, is invaded and cause by nature ailment said due to cold or exposure.All evil many can depend on wind and the convict such as cold, wet, dry, hot, as wind and cold, wind heat, rheumatism etc.Ailment said due to cold or exposure is the guide of exogenous diseases in fact.Wind being YANG-pathogen, its property using pungent drugs for dispersion and bitter drugs for purgation, has to rise and sends out, upwards outside characteristic.Top and flesh table therefore ailment said due to cold or exposure is often hurted sb.'s feelings, and see sweating, aversion to wind, headache, puffiness of face etc.Wind having the nature of shifting number becomes, and has morbidity anxious, and change is fast, and the walking of sick position is indefinite, the fickle characteristic of symptom.As migrans arthralgia; Skin pruritus, skin lesion appearing without definite location, rises one after another.
Along with the generally lifting of living condition, substantially air-conditioning is had at home, there is cold air in office, and to be busy with one's work and the rare time takes exercises, skin not perspire for a long time, the physiological regulation ability of response environment variations in temperature declines, and has if things go on like this increased the weight of ailment said due to cold or exposure harm in intrusive body, be the most intuitively cause that a lot of people is scorching at health, under direct sunlight or in sultry environment skin pruritus difficulty only, pain can't bear.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind ofly treats pharmaceutical composition of the caused skin pruritus of ailment said due to cold or exposure and preparation method thereof.
Technical problem to be solved by this invention is achieved by the following technical programs:
Treat a pharmaceutical composition for the caused skin pruritus of ailment said due to cold or exposure, described compositions comprises the component of following parts by weight: Radix Saposhnikoviae 6-8 part, Zaocys 2-4 part, Radix Cynanchi Paniculati 6-8 part, Herba Schizonepetae 2-4 part, Radix Angelicae Pubescentis 2-4 part, Fructus Kochiae 2-4 part, Cortex Dictamni 2-4 part, Herba Lobeliae Chinensis 2-4 part, Ramulus Cinnamomi 2-4 part.
Preferably, described compositions comprises the component of following parts by weight: Radix Saposhnikoviae 7 parts, Zaocys 3 parts, Radix Cynanchi Paniculati 7 parts, Herba Schizonepetae 3 parts, Radix Angelicae Pubescentis 3 parts, the Fructus Kochiae 3 parts, Cortex Dictamni 3 parts, Herba Lobeliae Chinensis 3 parts, Ramulus Cinnamomi 3 parts.
Further, preparation method comprises the steps: step one: the ethanol submergence ichthyosis bubble that Zaocys 3 parts use reaches 60% containing alcohol volume ratio was got filtrate after 15-20 days; Step 2: get Radix Saposhnikoviae 7 parts, Radix Cynanchi Paniculati 7 parts, Herba Schizonepetae 3 parts, Radix Angelicae Pubescentis 3 parts, the Fructus Kochiae 3 parts, Cortex Dictamni 3 parts, Herba Lobeliae Chinensis 3 parts, Ramulus Cinnamomi 3 parts of medical materials merging, decoct with water twice, amount of water is 10 times amount of medical material weight, decocts 2h, collecting decoction; Step 3: after filtrate and the mixing of the decocting liquid after merging, when being concentrated into 65 DEG C, relative density is 1.10, the ethanol used reaches 65% containing alcohol percent by volume, then stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20 and reclaims ethanol, by concentrated solution spraying dry, add adjuvant and make capsule, tablet, granule or pill.
Preferably, in described Zaocys ethanol immersion process, the frequency applying 600-700W every day is the ultrasound wave 5 minutes of 40KHz-45KHz.
A kind of pharmaceutical composition for the treatment of the caused skin pruritus of ailment said due to cold or exposure is applied in the skin pruritus caused by treatment ailment said due to cold or exposure as above.
The present invention has following beneficial effect:
The present invention uses Radix Saposhnikoviae, Zaocys, Radix Cynanchi Paniculati three taste monarch drug, effectively for the skin pruritus caused by ailment said due to cold or exposure, add Herba Schizonepetae again, Radix Angelicae Pubescentis, the Fructus Kochiae, Cortex Dictamni be additional strong therapeutic effect, also interpolation Herba Lobeliae Chinensis and Ramulus Cinnamomi successfully manage the scytitis that pruritus causes, whole formula gain is complementary, Synergistic, Be very effective.
In the present invention Zaocys preferably containing alcohol volume ratio reach 60% alcohol-pickled, and unconventional pulverizing is used as medicine, because inventor finds through making repeated attempts reaching in the ethanol of 60% soak containing alcohol volume ratio, and the frequency suitably applying 600-700W is the ultrasonic Treatment of 40KHz-45KHz, be used as medicine compared to directly beating powder, further process of the present invention enhances drug effect greatly, and the pharmacy also facilitating this component becomes agent.
Detailed description of the invention
The present invention will be described in detail for specific embodiment below.
Treat a pharmaceutical composition for the caused skin pruritus of ailment said due to cold or exposure, described compositions preferably includes the component of following parts by weight: Radix Saposhnikoviae 7 parts, Zaocys 3 parts, Radix Cynanchi Paniculati 7 parts, Herba Schizonepetae 3 parts, Radix Angelicae Pubescentis 3 parts, the Fructus Kochiae 3 parts, Cortex Dictamni 3 parts, Herba Lobeliae Chinensis 3 parts, Ramulus Cinnamomi 3 parts.
A kind of pharmaceutical composition for the treatment of the caused skin pruritus of ailment said due to cold or exposure; Its preparation method comprises the steps: step one: the ethanol submergence ichthyosis bubble that Zaocys 3 parts use reaches 60% containing alcohol volume ratio was got filtrate after 15-20 days, in described Zaocys ethanol immersion process, the frequency applying 600-700W every day is the ultrasound wave 5 minutes of 40KHz-45KHz; Step 2: get Radix Saposhnikoviae 7 parts, Radix Cynanchi Paniculati 7 parts, Herba Schizonepetae 3 parts, Radix Angelicae Pubescentis 3 parts, the Fructus Kochiae 3 parts, Cortex Dictamni 3 parts, Herba Lobeliae Chinensis 3 parts, Ramulus Cinnamomi 3 parts of medical materials merging, decoct with water twice, amount of water is 10 times amount of medical material weight, decocts 2h, collecting decoction; Step 3: after filtrate and the mixing of the decocting liquid after merging, when being concentrated into 65 DEG C, relative density is 1.10, the ethanol used reaches 65% containing alcohol percent by volume, then stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20 and reclaims ethanol, by concentrated solution spraying dry, add adjuvant and make capsule, tablet, granule or pill.
A kind of pharmaceutical composition for the treatment of the caused skin pruritus of ailment said due to cold or exposure is applied in the skin pruritus caused by treatment ailment said due to cold or exposure as above.
The above embodiment only have expressed embodiments of the present invention; it describes comparatively concrete and detailed; but therefore can not be interpreted as the restriction to the scope of the claims of the present invention; in every case the technical scheme adopting the form of equivalent replacement or equivalent transformation to obtain, all should drop within protection scope of the present invention.

Claims (5)

1. treat a pharmaceutical composition for the caused skin pruritus of ailment said due to cold or exposure, it is characterized in that described compositions comprises the component of following parts by weight: Radix Saposhnikoviae 6-8 part, Zaocys 2-4 part, Radix Cynanchi Paniculati 6-8 part, Herba Schizonepetae 2-4 part, Radix Angelicae Pubescentis 2-4 part, Fructus Kochiae 2-4 part, Cortex Dictamni 2-4 part, Herba Lobeliae Chinensis 2-4 part, Ramulus Cinnamomi 2-4 part.
2. a kind of pharmaceutical composition for the treatment of the caused skin pruritus of ailment said due to cold or exposure according to claim 1, is characterized in that described compositions comprises the component of following parts by weight: Radix Saposhnikoviae 7 parts, Zaocys 3 parts, Radix Cynanchi Paniculati 7 parts, Herba Schizonepetae 3 parts, Radix Angelicae Pubescentis 3 parts, the Fructus Kochiae 3 parts, Cortex Dictamni 3 parts, Herba Lobeliae Chinensis 3 parts, Ramulus Cinnamomi 3 parts.
3. a kind of preparation method for the treatment of the pharmaceutical composition of the caused skin pruritus of ailment said due to cold or exposure as claimed in claim 1 or 2, is characterized in that preparation method comprises the steps: step one: used by Zaocys 3 parts the ethanol submergence ichthyosis bubble reaching 60% containing alcohol percent by volume to get filtrate after 15-20 days; Step 2: get Radix Saposhnikoviae 7 parts, Radix Cynanchi Paniculati 7 parts, Herba Schizonepetae 3 parts, Radix Angelicae Pubescentis 3 parts, the Fructus Kochiae 3 parts, Cortex Dictamni 3 parts, Herba Lobeliae Chinensis 3 parts, Ramulus Cinnamomi 3 parts of medical materials merging, decoct with water twice, amount of water is 10 times amount of medical material weight, decocts 2h, collecting decoction; Step 3: after filtrate and the mixing of the decocting liquid after merging, when being concentrated into 65 DEG C, relative density is 1.10, the ethanol used reaches 65% containing alcohol volume ratio, then stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20 and reclaims ethanol, by concentrated solution spraying dry, add adjuvant and make capsule, tablet, granule or pill.
4. a kind of preparation method for the treatment of the pharmaceutical composition of the caused skin pruritus of ailment said due to cold or exposure according to claim 3, is characterized in that in Zaocys ethanol immersion process, and the frequency applying 600-700W every day is the ultrasound wave 5 minutes of 40KHz-45KHz.
5. the pharmaceutical composition that a kind of according to claim 1 or 2 or 3 or 4 treats the skin pruritus caused by ailment said due to cold or exposure is applied in the skin pruritus caused by treatment ailment said due to cold or exposure.
CN201510647744.7A 2015-10-09 2015-10-09 Medicinal composition for treating skin itch caused by pathogenic wind and preparation method thereof Pending CN105106374A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114886959A (en) * 2022-07-13 2022-08-12 云南琼月企业管理有限公司 Pharmaceutical composition, preparation and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080025513A (en) * 2006-09-18 2008-03-21 정풍훈 Composition of its manufacturing method for skin abirritant
CN103961437A (en) * 2014-05-20 2014-08-06 周鹏 Traditional Chinese medicine preparation for treating skin itch and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080025513A (en) * 2006-09-18 2008-03-21 정풍훈 Composition of its manufacturing method for skin abirritant
CN103961437A (en) * 2014-05-20 2014-08-06 周鹏 Traditional Chinese medicine preparation for treating skin itch and preparation method thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
卢祥之等: "《中华药酒谱》", 31 December 1997, 科学出版社 *
张穗坚: "《中国地道药材鉴别使用手册1》", 31 January 2010, 广东旅游出版社 *
徐玲: "《新编百草良方精粹》", 31 July 2012, 新世界出版社 *
杨卫平等: "《新编中草药图谱及经典配方.6》", 31 May 2014, 贵州科技出版社 *
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114886959A (en) * 2022-07-13 2022-08-12 云南琼月企业管理有限公司 Pharmaceutical composition, preparation and application thereof
CN114886959B (en) * 2022-07-13 2022-09-30 云南琼月企业管理有限公司 Pharmaceutical composition, preparation and application thereof

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Application publication date: 20151202