CN105079080A - Chinese herba preparation entada phaseoloides direct oral tablets for preventing and treating sexual apathy and preparation method of Chinese herba preparation entada phaseoloides direct oral tablets - Google Patents
Chinese herba preparation entada phaseoloides direct oral tablets for preventing and treating sexual apathy and preparation method of Chinese herba preparation entada phaseoloides direct oral tablets Download PDFInfo
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- CN105079080A CN105079080A CN201410206836.7A CN201410206836A CN105079080A CN 105079080 A CN105079080 A CN 105079080A CN 201410206836 A CN201410206836 A CN 201410206836A CN 105079080 A CN105079080 A CN 105079080A
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Abstract
The invention discloses Chinese herba preparation entada phaseoloides direct oral tablets for preventing and treating sexual apathy. Mature seeds of the entada phaseoloides serve as raw materials, and are fried, shelled, pulverized and packed to obtain the Chinese herba preparation entada phaseoloides direct oral tablets. The invention also discloses a preparation method of the Chinese herba preparation entada phaseoloides direct oral tablets. The preparation method comprises the following steps of (1) frying the mature seeds of the entada phaseoloides at the temperature of 120-250 DEG C; (2) shelling the fried seeds of the entada phaseoloides; (3) pulverizing the shelled seeds of the entada phaseoloides; and (4) packing the pulverized seeds of the entada phaseoloides to obtain the direct oral tablets. Compared with the prior art, the Chinese herba preparation entada phaseoloides direct oral tablets for preventing and treating sexual apathy have the advantages of obvious curative effect, low cost and convenience in preparation.
Description
Technical field
The present invention relates to a kind of for direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae and preparation method thereof, belong to medical art.
Background technology
Hyposexuality suppresses also referred to as libido, refers to that sex fantasy and the desire to sexual activity continue or deficiency repeatedly or lack completely.With the quickening pace of modern life with serious operating pressure, easily there is sexless state in modern female.The traditional Chinese medical science thinks that sexless sick position is at the heart, liver,spleen,kidney; The cause of disease is contain in the elder generation's deficiency day after tomorrow, feelings will internal injury, weakness due to chronic disease, phlegm-damp; Basic pathogenesis is the stagnation of QI, stagnation of phlegm, damage of essence, insufficiency of vital energy and blood.
Modern medicine, for clinical a certain symptom treatment, often falls flat, and can not find suitable Therapeutic Method.More existing Chinese medicinal composition preparation are used for the treatment of female frigidity at present, but these Chinese medicinal composition preparation prices are higher, make complicated.
Semen Entadae, has another name called and resembles bean, zygote, Ke, pulse family, evergreen wooden large liana.Be distributed in the ground such as Fujian, Taiwan, Guangdong, Hainan, Guangxi, Yunnan.Seed subcircular, diameter 4-6cm, flat, crineous, after ripe, seed coat is wooden, glossy, tool reticulate pattern.The florescence 3-4 month, fructescence late August.Containing two kinds of toxicity Saponins in seed kernel, act on similar, toxicity is equal.Eat seed by mistake, can cause dizziness, vomiting, blood pressure sharply declines, and breathes and to slow down and dead.Semen Entadae is mainly used in treating abdominal distention, jaundice, beriberi edema, dysentery, hemorrhoid, proctoptosis, sore throat etc.
Summary of the invention
The object of the present invention is to provide a kind of for direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae and preparation method thereof, provide a kind of evident in efficacy, with low cost, easy to make for the sexless Chinese medicine preparation of prevention and therapy.
For solving the problems of the technologies described above, the mature seed for the direct oral medicinal slice Yi Semen Entadae of prevention and therapy sexless Zhong Yao Ji Semen Entadae of the present invention is raw material, obtained through frying, shelling, pulverize, pack.
For solving the problems of the technologies described above, the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae of the present invention, the method comprises the steps:
The mature seed of Semen Entadae fries by step 1 , at 120 ~ 250 DEG C of temperature;
Step 2, removes decapsidate by the mackay bean fried;
Step 3, pulverizes the mackay bean except decapsidate;
Step 4, carries out the obtained direct oral medicinal slice of packaging by pulverizing mackay bean.
As improvement of the present invention, the time that fries in this step 1 is 1 ~ 3 hour.
As improvement of the present invention, the temperature that fries in this step 1 is 150 ~ 220 DEG C.
As improvement of the present invention, the temperature that fries in this step 1 is 180 ~ 190 DEG C.
As improvement of the present invention, the time that fries in this step 1 is 1.5 ~ 2.5 hours.
As improvement of the present invention, the time that fries in this step 1 is 1.8 ~ 2.2 hours.
As improvement of the present invention, the size after the pulverizing of this step 3 Zhong mackay bean is 800 ~ 1500 orders.
As improvement of the present invention, the size after the pulverizing of this step 3 Zhong mackay bean is 1000 ~ 1200 orders.
As improvement of the present invention, pulverize mackay bean in this step 4 and be packaged as 5 grams/bag.
Of the present invention for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae, the mature seed of cheap Zhong medicine Yuan Liao Semen Entadae can be utilized, by frying the toxicity of great large Jiang Di mackay bean, for women provides a kind of prevention and therapy sexless Chinese medicine preparation.Compared with prior art, of the present invention have the features such as evident in efficacy, with low cost, easy to make for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae.
Detailed description of the invention
Below in conjunction with specific embodiment, embodiment of the present invention are described in detail.Should be appreciated that enforcement of the present invention is not limited to the following examples, any pro forma accommodation make the present invention and/or change all will fall into protection scope of the present invention.
embodiment 1
The mature seed of 20 Qian Ke Semen Entadae is washed, dries.Drying mackay bean is put into frying pan fry, frying temperature is 120 DEG C, and the time of frying is 3 hours.The mackay bean fried is removed decapsidate and removes impurity, dry clean mackay bean Chinese medicine grinder except decapsidate is pulverized, fine powder after pulverizing is screened by 800 mesh sieves, fine powder excessive for granule is re-started pulverize and utilize, pack by screening mackay bean fine powder, the direct oral medicinal slice of obtained 5 grams/bag.
Toxicity test
Get Kunming mouse, SPF level, male and female half and half, body weight 18-22g, carry out LD
50trial test, finds out 0%(Dn) and 100%(Dm) estimate fatal dose.Mice is divided into two groups at random, namely give birth to product group and fry group, before experiment, embodiments of the invention 1 are prepared the direct oral medicinal slice of Semen Entadae and are dissolved in water, to mouse stomach by fasting 12 hours, gavage volume is 5ml/kg, the raw product of raw product group Gei Yu mackay bean fine powder, administration in 1 day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record toxic reaction and the death toll of mice.Experimental result shows that: mackay bean toxicity after frying is little compared with raw product, and concrete data are in table 1.
Clinical trial
The direct oral medicinal slice of embodiment 1 Zhong Semen Entadae is tried out in sexless women after marriage, case number is 100 people, take more than 5 days continuously, clinical test results shows: the direct oral medicinal slice of Semen Entadae can arouse Female sexual desire, have good prevention and therapy hyposexuality effect, concrete data are in table 2.
embodiment 2
The mature seed of 20 Qian Ke Semen Entadae is washed, dries.Drying mackay bean is put into frying pan fry, frying temperature is 150 DEG C, and the time of frying is 2.5 hours.The mackay bean fried is removed decapsidate and removes impurity, dry clean mackay bean Chinese medicine grinder except decapsidate is pulverized, fine powder after pulverizing is screened by 1000 mesh sieves, fine powder excessive for granule is re-started pulverize and utilize, pack by screening mackay bean fine powder, the direct oral medicinal slice of obtained 5 grams/bag.
Carry out toxicity test by the direct oral medicinal slice of embodiment 2 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 1.
Carry out clinical trial by the direct oral medicinal slice of embodiment 2 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 2.
embodiment 3
The mature seed of 20 Qian Ke Semen Entadae is washed, dries.Drying mackay bean is put into frying pan fry, frying temperature is 180 DEG C, and the time of frying is 2.2 hours.The mackay bean fried is removed decapsidate and removes impurity, dry clean mackay bean Chinese medicine grinder except decapsidate is pulverized, fine powder after pulverizing is screened by 1000 mesh sieves, fine powder excessive for granule is re-started pulverize and utilize, pack by screening mackay bean fine powder, the direct oral medicinal slice of obtained 5 grams/bag.
Carry out toxicity test by the direct oral medicinal slice of embodiment 3 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 1.
Carry out clinical trial by the direct oral medicinal slice of embodiment 3 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 2.
embodiment 4
The mature seed of 20 Qian Ke Semen Entadae is washed, dries.Drying mackay bean is put into frying pan fry, frying temperature is 190 DEG C, and the time of frying is 1.8 hours.The mackay bean fried is removed decapsidate and removes impurity, dry clean mackay bean Chinese medicine grinder except decapsidate is pulverized, fine powder after pulverizing is screened by 1200 mesh sieves, fine powder excessive for granule is re-started pulverize and utilize, pack by screening mackay bean fine powder, the direct oral medicinal slice of obtained 5 grams/bag.
Carry out toxicity test by the direct oral medicinal slice of embodiment 4 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 1.
Carry out clinical trial by the direct oral medicinal slice of embodiment 4 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 2.
embodiment 5
The mature seed of 20 Qian Ke Semen Entadae is washed, dries.Drying mackay bean is put into frying pan fry, frying temperature is 220 DEG C, and the time of frying is 1.5 hours.The mackay bean fried is removed decapsidate and removes impurity, dry clean mackay bean Chinese medicine grinder except decapsidate is pulverized, fine powder after pulverizing is screened by 1200 mesh sieves, fine powder excessive for granule is re-started pulverize and utilize, pack by screening mackay bean fine powder, the direct oral medicinal slice of obtained 5 grams/bag.
Carry out toxicity test by the direct oral medicinal slice of embodiment 5 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 1.
Carry out clinical trial by the direct oral medicinal slice of embodiment 5 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 2.
embodiment 6
The mature seed of 20 Qian Ke Semen Entadae is washed, dries.Drying mackay bean is put into frying pan fry, frying temperature is 250 DEG C, and the time of frying is 1 hour.The mackay bean fried is removed decapsidate and removes impurity, dry clean mackay bean Chinese medicine grinder except decapsidate is pulverized, fine powder after pulverizing is screened by 1500 mesh sieves, fine powder excessive for granule is re-started pulverize and utilize, pack by screening mackay bean fine powder, the direct oral medicinal slice of obtained 5 grams/bag.
Carry out toxicity test by the direct oral medicinal slice of embodiment 6 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 1.
Carry out clinical trial by the direct oral medicinal slice of embodiment 6 Zhong Semen Entadae according to the method for embodiment 1, the concrete data of experimental result are in table 2.
table 1
table 2
During the parch of mackay bean, sand can be added carry out parch together with mackay bean, You Li Yu mackay bean thermally equivalent.
During for prevention and therapy hyposexuality, the consumption of the direct oral medicinal slice of Zhong Yao Ji Semen Entadae of the present invention is each 1 bag, every day 1 ~ 3 time.
Of the present invention for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae, the mature seed of cheap Zhong medicine Yuan Liao Semen Entadae can be utilized, by frying the toxicity of great large Jiang Di mackay bean, for women provides a kind of prevention and therapy sexless Chinese medicine preparation.Compared with prior art, of the present invention have the features such as evident in efficacy, with low cost, easy to make for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae.
Claims (10)
1. one kind for the direct oral medicinal slice of the sexless middle medicine agent Semen Entadae of prevention and therapy, it is characterized in that: the described mature seed for the direct oral medicinal slice Yi Semen Entadae of prevention and therapy sexless Zhong Yao Ji Semen Entadae is raw material, obtained through frying, shelling, pulverize, pack.
2. the preparation method for the direct oral medicinal slice of the sexless middle medicine agent Semen Entadae of prevention and therapy according to claim 1, is characterized in that: the method comprises the steps:
The mature seed of Semen Entadae fries by step 1 , at 120 ~ 250 DEG C of temperature;
Step 2, removes decapsidate by the mackay bean fried;
Step 3, pulverizes the mackay bean except decapsidate;
Step 4, carries out the obtained direct oral medicinal slice of packaging by pulverizing mackay bean.
3. the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae according to claim 2, is characterized in that: the time that fries in described step 1 is 1 ~ 3 hour.
4. the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae according to claim 2, is characterized in that: the temperature that fries in described step 1 is 150 ~ 220 DEG C.
5. the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae according to claim 4, is characterized in that: the temperature that fries in described step 1 is 180 ~ 190 DEG C.
6. the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae according to claim 4, is characterized in that: the time that fries in described step 1 is 1.5 ~ 2.5 hours.
7. the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae according to claim 5, is characterized in that: the time that fries in described step 1 is 1.8 ~ 2.2 hours.
8. the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae according to claim 2, is characterized in that: the size after described step 3 Zhong mackay bean pulverizing is 800 ~ 1500 orders.
9. the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae according to claim 8, is characterized in that: the size after described step 3 Zhong mackay bean pulverizing is 1000 ~ 1200 orders.
10. the preparation method for the direct oral medicinal slice of prevention and therapy sexless Zhong Yao Ji Semen Entadae according to claim 2, is characterized in that: pulverize mackay bean in described step 4 and be packaged as 5 grams/bag.
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CN107998173A (en) * | 2017-12-18 | 2018-05-08 | 北京裕华佰奥生物技术有限公司 | The concocting method and its Suo get Ke vines micro mist, medicament of Yi Zhong Ke vines |
Citations (1)
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CN103191330A (en) * | 2013-04-16 | 2013-07-10 | 孔建 | Traditional Chinese medicine used for treating swelling of limbs of hemiplegic patient |
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CN103191330A (en) * | 2013-04-16 | 2013-07-10 | 孔建 | Traditional Chinese medicine used for treating swelling of limbs of hemiplegic patient |
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张耕等: "《常用中药毒性研究进展及应用》", 30 September 2013 * |
Cited By (1)
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CN107998173A (en) * | 2017-12-18 | 2018-05-08 | 北京裕华佰奥生物技术有限公司 | The concocting method and its Suo get Ke vines micro mist, medicament of Yi Zhong Ke vines |
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Application publication date: 20151125 |