CN105056397B - Implantable neural electrical stimulation electrode assemblie and its application process - Google Patents
Implantable neural electrical stimulation electrode assemblie and its application process Download PDFInfo
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- CN105056397B CN105056397B CN201510596458.2A CN201510596458A CN105056397B CN 105056397 B CN105056397 B CN 105056397B CN 201510596458 A CN201510596458 A CN 201510596458A CN 105056397 B CN105056397 B CN 105056397B
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Abstract
The present invention relates to a kind of implantable neural electrical stimulation electrode assemblie and its application process, the implantable neural electrical stimulation electrode assemblie, which includes an electrode catheter, the puncture needle and one for finding target spot, is used for the puncture tube for aiding in the electrode catheter to be put into target spot；The electrode catheter includes wire, protection sleeve pipe and fixture; the wire is located at the protection sleeve pipe and through the whole protection sleeve pipe; the fixture is sheathed on the predetermined position of the protection sleeve pipe; the protection sleeve pipe is one end open one end is closed, interior empty sleeve structure body; the open end of the protection sleeve pipe is provided with the connection end including multiple connecting terminals; closed end, which is provided with, includes the stimulation end of multiple stimulation contacts, and the middle part of the protection sleeve pipe is provided with fixture and visual label.
Description
Technical field
The invention belongs to implantation medical equipment manufacturing technology field, and in particular to a kind of implantable neural electrical stimulation electrode
Component and its application process.
Background technology
Implantable neural electrical stimulator is a kind of active implantable medical devices.Implantable neural electrical stimulator passes through
The mode of electro photoluminescence come it is excited, suppress or regulation nervous system conduction, recover or improve controlling for function of human body running so as to reach
Therapeutic effect.Implantable neural electrical stimulation therapy to more than 20 kind maladjusted nervous system diseases it is verified that have definite treatment
Effect.Compared with traditional pharmaceutical methods and surgical operation damage method, implantable nerve irritation therapy is reversible safely, in clinic
On just used more and more.Implantable neural electrical stimulator can be subdivided into implanted brain according to the difference of stimulation location
Deep brain stimulation system, implanted cortex stimulating system, implanted spinal cord stimulation trial system, implanted Sacral nerve electrical stimulation system
System, implanted vagus nerve electric stimulation etc., or be brain depth stimulator, vagus nerve stimulator, spinal stimulator, sacrum
Nerve stimulator, peripheral nerve stimulation device etc..
Similar with widely used cardiac pacemaker system, implantable neural electrical stimulator is also by generation stimulus signal
The electrode catheter composition of impulse generator and transmission stimulus signal.The signal that impulse generator is produced is delivered to by electrode catheter
Stimulation location（Target spot）Produce therapeutic effect.To obtain therapeutic effect steady in a long-term, it is necessary to which holding electrode is supravasal
Stimulate contact and target position constant.Therefore, when electrode catheter is implanted into, it should adopt an effective measure electrode catheter and tissue
It is fixed.
The class being widely used at present is by independent geometrical clamp（Or fixed sleeving, fixed anchor）Realized Deng device,
The relevant apparatus for example in U.S. Patent application US20090030492A1, US005484445A mentioned.
The electrode assemblie of this kind of implantable neural electrical stimulator is respectively fixed geometrical clamp and tissue, admittedly when being implanted into
Clamp is mutually fixed with electrode catheter, so that the fixation between electrode catheter and tissue is realized, this implantable neural electrical stimulation
Electrode assemblie usually requires larger operative incision, larger to damage to patient.
The content of the invention
In view of this, it is necessory to provide, a kind of simple in construction, doctor is easily operated, patient trauma is small, lower-cost
Implantable neural electrical stimulation electrode assemblie and its application process.
A kind of implantable neural electrical stimulation electrode assemblie includes setting on a puncture needle for being used to find target spot, the puncture needle
It is equipped with mark groove；One electrode catheter, it includes wire, protection sleeve pipe and fixture, and the wire is located at the protection sleeve pipe
And through the whole protection sleeve pipe, the fixture is sheathed on the predetermined position of the protection sleeve pipe, the protection sleeve pipe is
One end open one end closure, interior empty sleeve structure body, the protection sleeve pipe, adjacent with opening end are provided with
Connection end including multiple connecting terminals, the end adjacent with the closed end, which is provided with, includes the stimulation of multiple stimulation contacts
End, the middle part of the protection sleeve pipe, close to the stimulation end is provided with fixture, the connection end with it is described solid
Determine to be provided between part the first visual label of the monitoring to paracentesis depth when being implanted into for electrode catheter, the fixture is used
Fixed in the position after electrode catheter implantation；And, a puncture tube, for aiding in the electrode catheter to be put into target spot, institute
Puncture tube is stated for tubular body structure, the internal diameter of the puncture tube is more than the external diameter of the electrode catheter and the puncture needle, described
Puncture tube can be sheathed on the electrode catheter and the puncture needle, the puncture tube and be provided with mark groove.
The fixture includes multiple fixed-wings and a fixed part, and the multiple fixed-wing and a fixed part are structure as a whole
Body, the fixture is sheathed on the protection sleeve pipe by the fixed part, and each fixed-wing is connected with the fixed part, each
Direction of the free end away from the fixed part tilts extension to fixed-wing in a free state, collapsible by external force, releases external force bullet
Property affranchises state.
The material of the fixture is polyurethane, silicon rubber or polyurethane-silastic copolymer.
It is described to protect the middle part of sleeve pipe, be further provided with one second visual label, the second visual label position
Between first visual label and the connection end.
It is described to protect the middle part of sleeve pipe, two X-ray developing marks be further provided with, in the starting of the fixture
Position and terminated site respectively set one.
The wire is the stainless steel wire with insulating barrier, vitallium line, Nitinol line, platinumiridio line, tungsten
Alloy wire or carbon nano tube line.
The surface of the wire is further provided with improving the parylene coating or fluoroplastics of lubricity or biocompatibility
Coating.
The stimulation contact be platinum or platinumiridio, or surface covering platinum or platinumiridio coating loop configuration
Body.
A kind of application method of implantable neural electrical stimulation electrode assemblie, comprises the following steps:First, puncture needle is put into
Target spot is found in destination organization, and the puncture needle mark groove made exposes to destination organization；When the probe of puncture needle is found
To after target spot, puncture tube is placed in destination organization along the puncture needle so that mark groove on the puncture tube with
Mark groove alignment on the puncture needle, and the puncture needle is extracted；Afterwards, electrode catheter is passed through into the puncture tube
Hollow space is implanted into destination organization, treats that the visual label on electrode catheter aligns with the mark groove on puncture tube；Then from mesh
The fixed-wing for marking the fixture on the tissue extraction puncture tube, the electrode catheter opens, is embedded into destination organization, realizes and plants
Enter the fixation of the electrode catheter of formula nerve electric stimulation electrode assemblie.
Relative to prior art, the implantable neural electrical stimulation electrode assemblie that the present invention is provided has the advantages that：
The implant surgery of electrode becomes simple puncturing operation, also, puncture needle, puncture tube and electrode by traditional surgical operation
Conduit has corresponding visual label, and operation technique is simpler for doctor, the used time of performing the operation is reduced；For patient
Speech, can replace general anesthesia, anesthetic risks are greatly reduced with local anaesthesia, while puncturing operation wound is small, wound healing is fast,
So that patient is more comfortable.Therefore, the implantable neural electrical stimulation electrode assemblie of the invention provided is simple in construction, doctor is easy to behaviour
Make, patient trauma is small, cost is relatively low.
Brief description of the drawings
Fig. 1 is the schematic diagram for the implantable neural electrical stimulation electrode assemblie electrode catheter that first embodiment of the invention is provided.
Fig. 2 is the application decomposition schematic diagram for the implantable neural electrical stimulation electrode assemblie that first embodiment of the invention is provided.
Fig. 3 is the schematic diagram for the implantable neural electrical stimulation electrode assemblie electrode catheter that second embodiment of the invention is provided.
Fig. 4 is the schematic diagram for the implantable neural electrical stimulation electrode assemblie that second embodiment of the invention is provided.
Fig. 5 is the schematic diagram for the implantable neural electrical stimulation electrode assemblie electrode catheter that third embodiment of the invention is provided.
Fig. 6 is the schematic diagram for the implantable neural electrical stimulation electrode assemblie electrode catheter that fourth embodiment of the invention is provided.
Main element symbol description
| Electrode catheter | 100 |
| Handhold element | 101 |
| Connect end | 110 |
| Connecting terminal | 111 |
| Protect sleeve pipe | 120 |
| Opening | 121 |
| Closed end | 122 |
| Stimulate end | 140 |
| Stimulate contact | 141 |
| First visual label | 150 |
| Second visual label | 155 |
| Fixture | 160 |
| Fixed-wing | 161 |
| Fixed part | 162 |
| X-ray developing mark thing | 170 |
| Puncture needle | 300 |
| Puncture needle marks band | 310 |
| Puncture tube | 400 |
| Tissue | 180 |
| Target spot | 185 |
Following embodiment will further illustrate the present invention with reference to above-mentioned accompanying drawing.
Embodiment
Below with reference to accompanying drawing describe in detail implantable neural electrical stimulation electrode assemblie provided in an embodiment of the present invention and its
Application process.The example of the embodiment is shown in the drawings, wherein identical label represents identical components or with identical or class
Like the component of function.The embodiments described below with reference to the accompanying drawings are exemplary, it is intended to for explaining the present invention, and can not
It is interpreted as limitation of the present invention.
In the description of the invention, it is to be understood that term " longitudinal direction ", " transverse direction ", " on ", " under ", "front", "rear",
The orientation or position relationship of the instruction such as "left", "right", " vertical ", " level ", " top ", " bottom " " interior ", " outer " is based on accompanying drawing institutes
The orientation or position relationship shown, is for only for ease of the description present invention and simplifies description, rather than indicate or imply signified dress
Put or element there must be specific orientation, with specific azimuth configuration and operation, therefore it is not intended that to the limit of the present invention
System.
In the description of the invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection ", " fixation " should be interpreted broadly, for example, it may be fixedly connected or be detachably connected, or integration
Connection；Can be mechanical connection or electromagnetic force connection；Can be joined directly together, can also be indirect by intermediary
It is connected, can is the connection of two element internals.For the ordinary skill in the art, on being understood with concrete condition
State the concrete meaning of term in the present invention.
Fig. 1 and Fig. 2 is referred to, first embodiment of the invention provides implantable neural electrical stimulation electrode assemblie.It is described to plant
Entering formula nerve electric stimulation electrode assemblie includes electrode catheter 100, puncture needle 300 and puncture tube 400.The puncture needle 300 is used for
Target stimulation sites are found, target stimulation sites are medically also referred to as target spot 185.The puncture tube 400 is led for auxiliary electrode
Pipe 100 is put into target spot.The implantable neural electrical stimulation electrode assemblie of the present invention is sold as overall, and implantation to nerve is used as
The element of electro photoluminescence is the electrode catheter 100.
The electrode catheter 100 includes handhold element 101, wire (figure is not indicated), protection sleeve pipe 120 and fixture 160.
In the insertion of the handhold element 101 protection sleeve pipe 120, the rigidity for strengthening electrode facilitates operation technique.The wire is located at
The protection sleeve pipe 120 simultaneously protects sleeve pipe 120 through entirely described.The fixture 160 is sheathed on the protection sleeve pipe 120
Predetermined position.Handhold element 101 departs from electrode catheter, taken out after electrode catheter implantation.
The material of the wire can be the stainless steel wire of tape insulation layer, vitallium line, Nitinol line, platinumiridio
Line, tungsten alloy wire or carbon nano tube line etc., can be present for the form of twisted wire or helix, to improve overall anti-fatigue performance.
Further, it can make coating material to improve lubricity or biocompatibility on the surface of the wire, such as it is heavy on surface
Product parylene coating or plastic coating of fluoride etc..
The protection sleeve pipe 120 is that relative two ends are opening 121 and closed end 122, interior empty sleeve structure body, institute
The head for stating closed end 122 is smooth curved surface, such as hemispherical.It is the protection sleeve pipe 120, adjacent with the opening 121
End be provided with connection end 110, the end adjacent with the closed end 122 be provided with stimulation end 140.The protective case
The middle part of pipe 120, the close stimulation end 140 are provided with fixture 160, the connection end 110 and the fixture 160
Between be provided with visual label 150.The material of the protection sleeve pipe 120 can be common for polyurethane, silicon rubber or polyurethane-silicon rubber
Polymers etc..
The connection end 110 is provided with multiple connecting terminals 111, and the connecting terminal 111 can be loop configuration body, by
The conductive composition of the material with biocompatibility, such as MP35N or stainless steel.
The stimulation end 140 is provided with multiple stimulation contacts 141, and the stimulation contact 141 can be loop configuration body, by
The conductive composition of the material with biocompatibility, such as platinum or platinumiridio, or surface covering platinum or platinumiridio are applied
The material of layer, is electrically connected by way of resistance spot welding or laser spot welding with the wire.Contact is stimulated described in the present embodiment
141 be platinumiridio ring.
The pulse signal of the multiple connecting terminal 111 pulse signal different for receiving or different time sections, it is described
The pulse signal that multiple connecting terminals 111 are received is sent to different stimulation contacts 141 by different wires, multiple to realize
Contact 141 is stimulated to convey different pulse signal or the pulse signal of different time sections etc. to target spot 185.Corresponding connecting terminal
Connected between 111 and stimulation contact 141 by corresponding wire, adjacent the multiple connecting terminal 111 or the multiple thorn
Split between sharp contact 141 by insulator, to keep electrical isolation.
The visual label 150 is used for the monitoring to paracentesis depth when electrode catheter is implanted into, and can be in the protective case
Etched on pipe 120, brush, paste color or structure with obvious distinction, for example, brushed on the protection sleeve pipe 120 white
Vitta line, or paste white ribbon etc. on the protection sleeve pipe 120.In the present embodiment, the visual label 150 is with white
Silicon rubber thin band is pasted onto the mark band on the protection sleeve pipe 120.
In the present embodiment, the number of the fixture 160 is four, and each fixture 160 includes four Hes of fixed-wing 161
One fixed part 162, the fixture 160 is sheathed on the protection sleeve pipe 120, each fixed-wing by fixed part its described 162
161 are connected with the fixed part 162, each fixed-wing 161 direction of the free end away from the fixed part 162 in a free state
Tilt extension.The fixture 160, which is used for the position after the electrode catheter 100 is implanted into, to be fixed.The fixture 160 has single
Direction shrinkage, when the electrode catheter 100 is implanted into by the puncture tube 400, the fixed-wing 161 shrinks, convenient to puncture
Implantation, and the fixed-wing 161 is opened, is embedded into tissue automatically after the implantation, and fixation is produced to electrode catheter.
The material of the fixture 160 is polyurethane, silicon rubber or polyurethane-silastic copolymer.In the present embodiment, the fixture
160 are made by hardness for 80A silastic material, and the fixed part 162 of the fixture 160 is bonded in the guarantor by binder
On protecting pipe 120.
The puncture needle 300, which is used to find, be provided with target spot 185, the puncture needle 300 mark groove 310, described to wear
Thorn pipe 400 is used to aid in the stimulation contact 141 of the electrode catheter 100 to be put into the position of target spot 185.The puncture tube 400 it is interior
Caliber is more than the external diameter of the puncture needle 300 and electrode catheter 100, so that so that the puncture tube 400 is smoothly arranged
In the puncture needle 300 or electrode catheter 100.The puncture tube 400 is provided with mark groove (not indicating).Here by figure
2 further illustrate the application method for the implantable neural electrical stimulation electrode assemblie that the present embodiment is provided.Using the present invention's
The puncture needle 300 is first put into tissue 180 and searches out target spot 185 by implantable neural electrical stimulation electrode assemblie Shi doctor
Position, now the mark groove 310 of the puncture needle 300 expose to tissue 180, then along the puncture needle
300 place the puncture tube 400 in tissue 180 so that mark groove and the puncture needle on the puncture tube 400
Mark groove 310 on 300 aligns, and then extracts the puncture needle 300 from tissue 180, electrode catheter 100 is passed through into institute
The hollow space implantation tissue 180 of puncture tube 400 is stated, the visual label 150 and puncture tube 400 on electrode catheter 100 is treated
On mark groove alignment, that is, have shown electrode catheter reach precalculated position.Then the puncture tube is extracted from tissue 180
400, the fixed-wing 161 of the fixture 160 on the electrode catheter 100 opens, is embedded into tissue 180, realizes institute
State the fixation of electrode catheter 100.
Fig. 3 and Fig. 4 is referred to, the implantable neural electrical stimulation electrode assemblie and electrode that second embodiment of the invention is provided are led
Pipe 100.The implantable neural electrical stimulation electrode assemblie and electrode catheter 100 of the present embodiment and the implanted of above-mentioned first embodiment
Nerve electric stimulation electrode assemblie and electrode catheter 100 are essentially identical, and difference is that the electrode catheter 100 is further wrapped
One second visual label 155 is included, second visual label 155 and first visual label 150 are spaced apart, relative to
First visual label 150 is set close to the connection end 110, therefore, second visual label 155 is located at described first
Between visual label 150 and the connection end 110.
Using the implantable neural electrical stimulation electrode assemblie Shi doctor of the present embodiment by electrode catheter 100 along puncture tube 400
Insert human body, when the first visual label 150 of electrode catheter 100 aligns with the top surface of puncture tube 400, electrode catheter 100
Stimulate end 140 to reach precalculated position, now stop the insert action of electrode catheter 100；Then holding electrode conduit 100 is not
It is dynamic, puncture tube 400 is outwards pulled out, when the top surface of puncture tube 400 aligns with the second visual label 155 of electrode catheter 100, electricity
The fixture 160 of pole conduit 100 fully extended puncture tube 400.When the fixture 160 of electrode catheter 100 is in puncture tube 400
Its fixed-wing 161 is in compressive state, now has larger frictional force between electrode catheter 100 and puncture tube 400, in this phase
Between, doctor should carefully be operated, it is to avoid electrode catheter 100 or puncture tube 400 are moved with other side.
Referring to Fig. 5, the electrode catheter for the implantable neural electrical stimulation electrode assemblie that third embodiment of the invention is provided
100.The electrode catheter 100 of the implantable neural electrical stimulation electrode assemblie of the present embodiment and the implanted god of above-mentioned first embodiment
Electrode catheter 100 through electric stimulation electrode component is essentially identical, and difference is that the electrode catheter 100 further comprises
Two X-ray developing marks 170, are arranged at starting position and each one of the terminated site of the fixture 160.The X-ray development
Mark 170 is used for after electrode catheter 100 is implanted into the position that fixture 160 is determined under X-ray.The X-ray developing mark 170 by
Larger material of decaying to X-ray absorption makes, such as the polymer of tantalum, platinum, platinumiridio, platinum-tungsten alloys or baric.This
In embodiment, X-ray developing mark 170 is made by platinumiridio.
Referring to Fig. 6, the electrode catheter for the implantable neural electrical stimulation electrode assemblie that fourth embodiment of the invention is provided
100.The electrode catheter 100 of the implantable neural electrical stimulation electrode assemblie of the present embodiment and the implanted god of above-mentioned second embodiment
The essentially identical difference of electrode catheter 100 through electric stimulation electrode component is that the electrode catheter 100 further comprises two
Individual X-ray developing mark 170, is arranged at starting position and each one of the terminated site of the fixture 160.The X-ray development mark
Note 170 is used for after electrode catheter 100 is implanted into the position that fixture 160 is determined under X-ray.The X-ray developing mark 170 is by right
The material making that X-ray absorption is decayed larger, such as the polymer of tantalum, platinum, platinumiridio, platinum-tungsten alloys or baric.This reality
Apply in example, X-ray developing mark 170 is made by platinumiridio.
Relative to prior art, the implantable neural electrical stimulation electrode assemblie that the present invention is provided has the advantages that：
The implant surgery of electrode becomes simple puncturing operation, also, puncture needle, puncture tube and electrode by traditional surgical operation
Conduit has corresponding visual label, and operation technique is simpler for doctor, the used time of performing the operation is reduced；For patient
Speech, can replace general anesthesia, anesthetic risks are greatly reduced with local anaesthesia, while puncturing operation wound is small, wound healing is fast,
So that patient is more comfortable.Therefore, the implantable neural electrical stimulation electrode assemblie of the invention provided is simple in construction, doctor is easy to behaviour
Make, patient trauma is small, cost is relatively low.
In addition, those skilled in the art can also do other changes in spirit of the invention, certainly, these are according to present invention essence
The change that god is done, should all be included within scope of the present invention.
Claims (8)
1. a kind of implantable neural electrical stimulation electrode assemblie, it is characterised in that including:
Mark groove is provided with one puncture needle for finding target spot, the puncture needle；
One electrode catheter, it includes wire, protection sleeve pipe and fixture, and the wire is located at the protection sleeve pipe and through whole
The protection sleeve pipe, the fixture is sheathed on the predetermined position of the protection sleeve pipe, and the protection sleeve pipe is one end open one
End closure, interior empty sleeve structure body, the protection sleeve pipe, adjacent with opening end are provided with including multiple companies
The connection end of contact point, the end adjacent with the closed end, which is provided with, includes the stimulation end of multiple stimulation contacts, described
Protect the middle part of sleeve pipe, the stimulation end be provided with fixture, between the connection end and the fixture
First visual label of the monitoring to paracentesis depth being provided with when being implanted into for electrode catheter, the fixture is used for the electricity
Position after the implantation of pole conduit is fixed, and the fixture includes multiple fixed-wings and a fixed part, each fixed-wing with it is described solid
Determine portion to be connected, each fixed-wing tilts extension in direction of the free end away from the fixed part in a free state, can be received by external force
Contracting, releases external force elasticity and affranchises state, and,
One puncture tube, for aiding in the electrode catheter to be put into target spot, the puncture tube is tubular body structure, the puncture tube
Internal diameter is more than the external diameter of the electrode catheter and the puncture needle, and the puncture tube can be sheathed on the electrode catheter and described
Mark groove is provided with puncture needle, the puncture tube.
2. implantable neural electrical stimulation electrode assemblie as claimed in claim 1, it is characterised in that the multiple fixed-wing and one
Fixed part is structure as a whole body, and the fixture is sheathed on the protection sleeve pipe by the fixed part.
3. implantable neural electrical stimulation electrode assemblie as claimed in claim 2, it is characterised in that the material of the fixture is
Polyurethane, silicon rubber or polyurethane-silastic copolymer.
4. implantable neural electrical stimulation electrode assemblie as claimed in claim 1, it is characterised in that the centre of the protection sleeve pipe
Position, it is further provided with one second visual label, second visual label is located at first visual label and the company
Connect between end.
5. the implantable neural electrical stimulation electrode assemblie as described in claim 1 or 4, it is characterised in that the protection sleeve pipe
Middle part, two X-ray developing marks are further provided with, one is respectively set in the starting position of the fixture and terminated site
It is individual.
6. implantable neural electrical stimulation electrode assemblie as claimed in claim 1, it is characterised in that the wire is tape insulation layer
Stainless steel wire, vitallium line, Nitinol line, platinumiridio line, tungsten alloy wire or carbon nano tube line.
7. implantable neural electrical stimulation electrode assemblie as claimed in claim 6, it is characterised in that the surface of the wire enters one
Step, which is provided with, improves the parylene coating or plastic coating of fluoride of lubricity or biocompatibility.
8. implantable neural electrical stimulation electrode assemblie as claimed in claim 1, it is characterised in that the stimulation contact be platinum or
Platinumiridio, or surface cover the loop configuration body of platinum or platinumiridio coating.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106693163B (en) * | 2016-12-09 | 2019-10-29 | 北京品驰医疗设备有限公司 | A kind of directionality DBS electrode and its localization method with cue mark |
| CN107812312A (en) * | 2017-10-13 | 2018-03-20 | 北京品驰医疗设备有限公司 | A kind of expanding pilot device |
| CN107982632A (en) * | 2017-10-13 | 2018-05-04 | 复旦大学附属眼耳鼻喉科医院 | Animal artificial cochlea electrode implant and application thereof |
| CN109011136A (en) * | 2018-09-05 | 2018-12-18 | 中国人民解放军陆军总医院 | Deep brain stimulation electrode component, lesions located in deep brain device and its application method |
| CN109908467B (en) * | 2019-04-25 | 2024-04-30 | 北京品驰医疗设备有限公司 | Nerve electric stimulation electrode assembly and preparation method thereof |
| CN111686369B (en) * | 2020-06-22 | 2024-02-27 | 山东大学齐鲁医院 | Barb device and system for preventing sacral nerve stimulating electrode from inward displacement |
| CN111729193B (en) * | 2020-06-24 | 2023-05-30 | 北京品驰医疗设备有限公司 | Isolation ring, composite contact, electrode and manufacturing method of electrode |
| CN112604155B (en) * | 2020-12-31 | 2024-05-28 | 北京品驰医疗设备有限公司 | Method for manufacturing direction electrode developing mark and direction electrode developing mark |
| CN114177517A (en) * | 2022-02-15 | 2022-03-15 | 杭州神络医疗科技有限公司 | Nerve stimulation electrode and nerve stimulation device |
Citations (1)
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|---|---|---|---|---|
| CN104302355A (en) * | 2012-12-31 | 2015-01-21 | 上海微创医疗器械（集团）有限公司 | Cardiac electrical lead |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US8224456B2 (en) * | 2003-11-25 | 2012-07-17 | Advanced Neuromodulation Systems, Inc. | Directional stimulation lead and orientation system |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104302355A (en) * | 2012-12-31 | 2015-01-21 | 上海微创医疗器械（集团）有限公司 | Cardiac electrical lead |
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