CN105030972A - Traditional Chinese medicine preparation for treating adenoidal hypertrophy of children - Google Patents
Traditional Chinese medicine preparation for treating adenoidal hypertrophy of children Download PDFInfo
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- CN105030972A CN105030972A CN201510586273.3A CN201510586273A CN105030972A CN 105030972 A CN105030972 A CN 105030972A CN 201510586273 A CN201510586273 A CN 201510586273A CN 105030972 A CN105030972 A CN 105030972A
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Abstract
The invention belongs to the technical field of medicines and particularly relates to a traditional Chinese medicine preparation for treating adenoidal hypertrophy of children and a preparation method thereof. The traditional Chinese medicine preparation is prepared by, radix astragali, radix pseudostellariae, ligusticum wallichii, corydalis tubers, kelps, forsythia, cocklebur fruits, borneol, dried tangerine or orange peels and platicodon grandiflorum. The traditional Chinese medicine preparation is reasonable in combination, is easy to prepare, has remarkable treating effects of tonifying spleen, moistening lung, promoting qi to activate blood, resolving hard lump to dissipate stagnation, relieving throat sore and reducing phlegm and is an effective medicine for treating the adenoidal hypertrophy of the children, especially qi-blood stasis and stagnation type adenoidal hypertrophy of the children.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine preparation for the treatment of children with adenoid hypertrophy.
Background technology
Children with adenoid hypertrophy often belongs to physiological disorder because nasopharynx part has lymphoid tissue during baby due, and with the age hypertrophy, reach when 6 years old at utmost, degenerate gradually later, if it affects whole body health or adjacent organs person, just claim adenoid vegetation.Adenoid vegetation common clinical disease comprises acute tonsillitis, acute rhinitis, and influenza etc., often arises from pharyngeal infection and inflammatory stimulus repeatedly, more common in the area of cold wet and climate variability.Adenoid vegetation can cause OSAHS (obstruction sleep apnea-hypopnea syndrome), sinusitis, a series of disease such as secretory otitis media, serious shadow noon children life quality and physique, intelligent development.
In treatment, doctor trained in Western medicine is divided into expectant treatment and surgical resection therapy.Mostly expectant treatment is oral antibiotic, hormone or nasal spray, Neulized inhalation etc., but children toleration is poor, and side effect is large, not easily continued treatment.Misgivings and fear is had for the many heads of a family of surgical resection therapy and infant, child's proventriculus type is also important immune organ simultaneously, to child, particularly the child throat in 3-5 year and the Effects on local immunological functions of whole upper respiratory tract have important effect, therefore now increasing infants ' parents to seek curative effect more definite, treating both the principal and secondary aspects of a disease, safe and reliable Chinese medicine carries out symptomatic treatment.
Summary of the invention
In order to solve the problem, the present invention aims to provide a kind of Chinese medicine preparation and preparation method thereof for the treatment of children with adenoid hypertrophy particularly qi and blood stagnation type children with adenoid hypertrophy.
An object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of qi and blood stagnation type children with adenoid hypertrophy.
Another object of the present invention is to provide a kind of preparation method for the treatment of the Chinese medicine preparation of qi and blood stagnation type children with adenoid hypertrophy.
The present invention treats the Chinese medicine preparation of qi and blood stagnation type children with adenoid hypertrophy, its active ingredient is made up of the crude drug of following weight proportion: Radix Astragali 13-15 part, Radix Pseudostellariae 6-8 part, Rhizoma Chuanxiong 3-5 part, Rhizoma Corydalis 10-12 part, Thallus Laminariae (Thallus Eckloniae) 8-10 part, Fructus Forsythiae 4-6 part, Fructus Xanthii 8-10 part, Borneolum Syntheticum 1-3 part, Pericarpium Citri Reticulatae 8-10 part, Radix Platycodonis 7-9 part.
Optimal technical scheme of the present invention is that Chinese medicine preparation of the present invention is obtained by the crude drug of following weight proportion: the Radix Astragali 14 parts, Radix Pseudostellariae 7 parts, Rhizoma Chuanxiong 4 parts, Rhizoma Corydalis 11 parts, Thallus Laminariae (Thallus Eckloniae) 9 parts, Fructus Forsythiae 5 parts, Fructus Xanthii 9 parts, Borneolum Syntheticum 2 parts, Pericarpium Citri Reticulatae 9 parts, Radix Platycodonis 8 parts.
The Chinese medicine preparation that the present invention treats children with adenoid hypertrophy can also contain pharmaceutically acceptable carrier, is prepared into conventional formulation, as capsule, granule or oral liquid, is preferably oral liquid.
The preparation method step of described oral liquid is as follows:
(1) according to aforesaid weight take above except Borneolum Syntheticum other Chinese medicine components be ground into coarse powder respectively; The water that first time adds medical material gross weight 6 times amount, soaks 4h, decocts 3h, filter while hot; Medicinal residues add the water of 4 times amount again, decoct 2h, filter while hot; Merge twice and decoct filtrate; When filtrate is concentrated into 75 DEG C, relative density is the extractum of 1.15 ~ 1.21, naturally cools to room temperature;
(2) in extractum, add Borneolum Syntheticum and the ethanol of ground recipe quantity, it is 45% ~ 65% that limit edged is stirred to alcohol content, then standing sedimentation 24 ~ 48h, filter, gained filtrate recycling ethanol, to without alcohol taste, then adds distilled water dosing, potassium sorbate with 0.1% regulates pH to 7.0 ~ 7.5, adding distil water is to enough again, with moist hear heat test sterilizing 30 minutes after fill, obtains oral solutions of the present invention.
The present invention relatively and prior art, has following clear superiority:
First, Chinese medicine preparation prescription of the present invention mainly develops according to the pathogenic characteristic of qi and blood stagnation type children with adenoid hypertrophy, and qi and blood stagnation type children with adenoid hypertrophy disease is seen: with the passing of time nasal obstruction, continues not subtract, sleep middle Xuan sound time do; In ear is vexed swollen, auditory dysesthesia; Proventriculus type enlargement is dark red, the upper cloth blood streak, and that touches is stronger, does not with the passing of time heal, dimly red tongue or have addiction speckle, and arteries and veins is excessive.The Radix Astragali in side, Radix Pseudostellariae, invigorating QI to consolidate the body surface resistance, spleen invigorating lung moistening; Rhizoma Chuanxiong, Rhizoma Corydalis, blood-activating and qi-promoting, blood-activating analgetic; Thallus Laminariae (Thallus Eckloniae), Fructus Forsythiae, hard masses softening and resolving, heat-clearing and toxic substances removing; Fructus Xanthii, Borneolum Syntheticum, sensible refreshment, dispelling wind for relieving itching; Pericarpium Citri Reticulatae, Radix Platycodonis, sore-throat relieving reduces phlegm, spleen invigorating lung qi dispersing; All medicines share, and spleen invigorating lung moistening is played, promoting flow of QI and blood, hard masses softening and resolving, the special effect that sore-throat relieving reduces phlegm altogether by full side, to children with adenoid hypertrophy particularly qi and blood stagnation type children with adenoid hypertrophy have extremely strong specific aim curative effect, and onset is rapid, treating both the principal and secondary aspects of a disease.
Secondly, Chinese medicine preparation of the present invention adopts sophisticated equipment and technique preparation, and dosage form is advanced, taking convenience, child patient better tolerance.
3rd, after 1 course for the treatment of of clinical observation, total effective rate comparison therapy group 95%, matched group 67.5%, two groups of total effective rates compare, and treatment group has more significantly clinical efficacy, has and studies and the value applied further.
Further, in Chinese medicine preparation of the present invention, the function of each crude drug cures mainly:
The Radix Astragali, sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Radix Pseudostellariae, sweet, micro-hardship, flat.Return spleen, lung meridian.Replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Rhizoma Chuanxiong, pungent, temperature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea ， mass in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Rhizoma Corydalis, pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Thallus Laminariae (Thallus Eckloniae) is salty, cold.Return liver, stomach, kidney channel.Hard masses softening and resolving, expectorant, diuretic.For goiter, scrofula, painful and swollen testis, phlegm retention edema.
Fructus Forsythiae, bitter, be slightly cold.Return lung, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Fructus Xanthii, bitter in the mouth, sweet, pungent, warm in nature.Mild toxicity, returns lung, Liver Channel.Dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, antipruritic.Main nasal sinusitis, headche due to wind-cold, rheumatic arthralgia, rubella, eczema, scabies.
Borneolum Syntheticum, pungent, bitter, be slightly cold.GUIXIN, spleen, lung meridian.To have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Pericarpium Citri Reticulatae, bitter, pungent, temperature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Radix Platycodonis, bitter, pungent, flat.Return lung meridian.Lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, but the present invention is not limited only to following specific embodiment.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the change carried out the present invention, combination or replacement, be apparent for a person skilled in the art, and be included within the scope of the present invention.
Embodiment 1 oral liquid
The each crude drug of the present invention is taken: the Radix Astragali 14 parts, Radix Pseudostellariae 7 parts, Rhizoma Chuanxiong 4 parts, Rhizoma Corydalis 11 parts, Thallus Laminariae (Thallus Eckloniae) 9 parts, Fructus Forsythiae 5 parts, Fructus Xanthii 9 parts, Borneolum Syntheticum 2 parts, Pericarpium Citri Reticulatae 9 parts, Radix Platycodonis 8 parts by following weight portion.
Preparation technology is as follows:
(1) according to aforesaid weight take above except Borneolum Syntheticum other Chinese medicine components be ground into coarse powder respectively; The water that first time adds medical material gross weight 6 times amount, soaks 4h, decocts 3h, filter while hot; Medicinal residues add the water of 4 times amount again, decoct 2h, filter while hot; Merge twice and decoct filtrate; When filtrate is concentrated into 75 DEG C, relative density is the extractum of 1.21, naturally cools to room temperature;
(2) in extractum, add Borneolum Syntheticum and the ethanol of ground recipe quantity, it is 50% that limit edged is stirred to alcohol content, then standing sedimentation 48h, filter, gained filtrate recycling ethanol, to without alcohol taste, then adds distilled water dosing, potassium sorbate with 0.1% regulates pH to 7.5, adding distil water is to enough again, with moist hear heat test sterilizing 30 minutes after fill, to obtain final product.
When using Chinese medicine preparation of the present invention to treat children with adenoid hypertrophy, take the oral liquid of preparation, every bottle of 10ml, containing crude drug amount 0.6g, each 1 bottle, every day 2 times, take half an hour after meal.
Embodiment 2 oral liquid
The each crude drug of the present invention is taken: the Radix Astragali 14 parts, Radix Pseudostellariae 7 parts, Rhizoma Chuanxiong 4 parts, Rhizoma Corydalis 11 parts, Thallus Laminariae (Thallus Eckloniae) 9 parts, Fructus Forsythiae 5 parts, Fructus Xanthii 9 parts, Borneolum Syntheticum 2 parts, Pericarpium Citri Reticulatae 9 parts, Radix Platycodonis 8 parts by following weight portion.
Preparation technology is as follows:
(1) according to aforesaid weight take above except Borneolum Syntheticum other Chinese medicine components be ground into coarse powder respectively; The water that first time adds medical material gross weight 6 times amount, soaks 4h, decocts 3h, filter while hot; Medicinal residues add the water of 4 times amount again, decoct 2h, filter while hot; Merge twice and decoct filtrate; When filtrate is concentrated into 75 DEG C, relative density is the extractum of 1.15, naturally cools to room temperature;
(2) in extractum, add Borneolum Syntheticum and the ethanol of ground recipe quantity, it is 45% that limit edged is stirred to alcohol content, then standing sedimentation 24h, filter, gained filtrate recycling ethanol, to without alcohol taste, then adds distilled water dosing, potassium sorbate with 0.1% regulates pH to 7.0, adding distil water is to enough again, with moist hear heat test sterilizing 30 minutes after fill, to obtain final product.
When using Chinese medicine preparation of the present invention to treat children with adenoid hypertrophy, take the oral liquid of preparation, every bottle of 10ml, containing crude drug amount 0.6g, each 1 bottle, every day 2 times, take half an hour after meal.
Embodiment 3 oral liquid
The each crude drug of the present invention is taken: the Radix Astragali 14 parts, Radix Pseudostellariae 7 parts, Rhizoma Chuanxiong 4 parts, Rhizoma Corydalis 11 parts, Thallus Laminariae (Thallus Eckloniae) 9 parts, Fructus Forsythiae 5 parts, Fructus Xanthii 9 parts, Borneolum Syntheticum 2 parts, Pericarpium Citri Reticulatae 9 parts, Radix Platycodonis 8 parts by following weight portion.
Preparation technology is as follows:
(1) according to aforesaid weight take above except Borneolum Syntheticum other Chinese medicine components be ground into coarse powder respectively; The water that first time adds medical material gross weight 6 times amount, soaks 4h, decocts 3h, filter while hot; Medicinal residues add the water of 4 times amount again, decoct 2h, filter while hot; Merge twice and decoct filtrate; When filtrate is concentrated into 75 DEG C, relative density is the extractum of 1.15, naturally cools to room temperature;
(2) in extractum, add Borneolum Syntheticum and the ethanol of ground recipe quantity, it is 65% that limit edged is stirred to alcohol content, then standing sedimentation 36h, filter, gained filtrate recycling ethanol, to without alcohol taste, then adds distilled water dosing, potassium sorbate with 0.1% regulates pH to 7.5, adding distil water is to enough again, with moist hear heat test sterilizing 30 minutes after fill, to obtain final product.
When using Chinese medicine preparation of the present invention to treat children with adenoid hypertrophy, take the oral liquid of preparation, every bottle of 10ml, containing crude drug amount 0.6g, each 1 bottle, every day 2 times, take half an hour after meal.
Embodiment 4 oral liquid
The each crude drug of the present invention is taken: the Radix Astragali 15 parts, Radix Pseudostellariae 8 parts, Rhizoma Chuanxiong 5 parts, Rhizoma Corydalis 12 parts, Thallus Laminariae (Thallus Eckloniae) 10 parts, Fructus Forsythiae 6 parts, Fructus Xanthii 10 parts, Borneolum Syntheticum 3 parts, Pericarpium Citri Reticulatae 10 parts, Radix Platycodonis 9 parts by following weight portion.
Preparation technology is with embodiment 1.
Embodiment 5 oral liquid
The each crude drug of the present invention is taken: the Radix Astragali 13 parts, Radix Pseudostellariae 6 parts, Rhizoma Chuanxiong 3 parts, Rhizoma Corydalis 10 parts, Thallus Laminariae (Thallus Eckloniae) 8 parts, Fructus Forsythiae 4 parts, Fructus Xanthii 8 parts, Borneolum Syntheticum 1 part, Pericarpium Citri Reticulatae 8 parts, Radix Platycodonis 7 parts by following weight portion.
Preparation technology is with embodiment 1.
The clinical observation of embodiment 6 Drug therapy qi and blood stagnation of the present invention type adenoid vegetation
1, physical data:
Select hospital outpatient and ward to be diagnosed as infant 80 example of qi and blood stagnation type children's adenoid vegetation, age 3-9 year, the course of disease 6 months-2 years, is divided into treatment group and matched group at random, often organizes 40 examples.In the routine infant for the treatment of group 40, man 24 example, female 16 example; In the routine infant of matched group 40, man 22 example, female 18 example.The data of two groups of patients comprises sex, age, the course of disease, state of an illness aspect etc. and compares, and there was no significant difference, P > 0.05, has comparability.
2, diagnostic criteria:
Tcm diagnosis qi and blood stagnation type children's adenoid vegetation disease is seen: with the passing of time nasal obstruction, continues not subtract, do during the middle sound of snoring of sleeping; In ear is vexed swollen, auditory dysesthesia; Paraphyte enlargement is dark red, the upper cloth blood streak, and that touches is stronger, does not with the passing of time heal, dimly red tongue or have ecchymosis, hesitant pulse.
Western medicine diagnose standard: discontinuity or persistent upper respiratory obstructive symptom, as recurrent exerbation such as nasal obstruction, sleep snoring, mouth breathings, or there is proventriculus type sample face in child.Auxiliary examination: visible adenoid vegetation under Electronic Nose pharyngoscope or fiberoptic nasopharyngoscope.Image check: Nasopharynx lateral film or nasopharynx CT median sagittal plane record ratio (A/N) > 0.6 of proventriculus type thickness and nasopharynx air cavity anteroposterior diameter, can make a definite diagnosis.
3, case standard is included in
(1) meet Western medicine diagnose standard and tcm diagnosis standard, Chinese medical discrimination is qi and blood stagnation type;
(2) age (comprised 3 years old) more than 3 years old, less than 9 years old (comprising 9 years old);
(3) auxiliary examination: the display proventriculus type such as the film making of position, x-ray nasopharynx side, nasopharyngeal endoscope hypertrophy in various degree;
(4) outpatient service or Hospitalized Children, head of a family's informed consent, and be ready long-term partner treatment person.
4, Excluded cases standard
(1) tonsil III ° of enlargement, the severe sound of snoring, even there is obstructive sleep respiratory disorder, represent that proventriculus type, tonsil have danger, should be considered as that there is surgical indication have allergies or allergic constitution person, children with bronchial asthma disease;
(2) age is below 3 years old or more than 9 years old person;
(3) do not meet inclusive criteria, or the serious song partially of nasal septum affects ventilation person;
(4) complication severe patient, the disease that is infectious patient or serious systemic disease person;
(5) participated in or participated in drug administration process the clinical observers of other medicines.
5, to come off and termination criteria:
(1) observe in patient exit voluntarily, person lost to follow-up;
(2) there is the person that should not continue reception test such as complication or special physiological change in experimenter;
(3) serious adverse reaction occurs person in test, should stop clinical trial in time.
Come off and answer itemized record reason with the case stopped, and the switching of its last curative effect testing result is added up for final result.
6, Therapeutic Method:
Treatment group: oral liquid prepared by the oral embodiment of the present invention 1, every bottle of 10ml, containing crude drug amount 0.6g, each 1 bottle, every day 2 times, takes after meal half an hour.
Matched group: nasonex, 50ug*140 presses/bottle/box, authentication code: 20141000H manufacturing enterprise: Schering-PloughLaboN.V, nostril, every side 1 is sprayed (often spray is 50 μ g), 1 time on the one (total amount is 100 μ g).
Two groups of equal continuous application of medicine 30 days are a course for the treatment of, and observing time is a course for the treatment of.Viewing duration prohibits the use the medicine of other treatment adenoid vegetation.
7, curative effect determinate standard:
Result synthetic determination is improved according to pharyngorhinoscopy and clinical symptoms.
Effective: clinical symptoms disappears substantially, pharyngorhinoscopy recovers obviously;
Effective: clinical symptom relief, pharyngorhinoscopy takes a turn for the better or to some extent without significant change;
Invalid: clinical symptoms is not improved, pharyngorhinoscopy is unchanged or increase the weight of.
Total effective rate=(effective number of cases+effectively number of cases)/total number of cases × 100%.
8, therapeutic effect:
80 routine patients all complete clinical observation, without coming off, exiting case.Carry out observation and comparison to the therapeutic effect of two groups of patients after 1 course for the treatment of, the routine infant for the treatment of group 40,24 examples are effective, and effectively, 2 examples are invalid, total effective rate 95%, the routine infant of matched group 40 for 14 examples, and 8 examples are effective, and effectively, 13 examples are invalid, total effective rate 67.5% for 19 examples.
Above-mentioned clinical effectiveness shows, treatment group therapeutic effect is obviously better than matched group.In safety evaluatio, treatment group occurs without uncomfortable sensation and complication in the therapeutic process of the whole course for the treatment of simultaneously, before and after treatment group treatment, the check result such as routine blood test, routine urinalysis, just routine, liver function, kidney merit, myocardium enzyme, blood biochemistry, blood glucose is without significant change, show that our clinical application is safely and effectively, be worth studying and applying further.
Claims (7)
1. treat the Chinese medicine preparation of children with adenoid hypertrophy for one kind, it is characterized in that, it is obtained by the crude drug of following weight portion: Radix Astragali 13-15 part, Radix Pseudostellariae 6-8 part, Rhizoma Chuanxiong 3-5 part, Rhizoma Corydalis 10-12 part, Thallus Laminariae (Thallus Eckloniae) 8-10 part, Fructus Forsythiae 4-6 part, Fructus Xanthii 8-10 part, Borneolum Syntheticum 1-3 part, Pericarpium Citri Reticulatae 8-10 part, Radix Platycodonis 7-9 part.
2. Chinese medicine preparation as claimed in claim 1, it is characterized in that, it is obtained by the crude drug of following weight portion: the Radix Astragali 14 parts, Radix Pseudostellariae 7 parts, Rhizoma Chuanxiong 4 parts, Rhizoma Corydalis 11 parts, Thallus Laminariae (Thallus Eckloniae) 9 parts, Fructus Forsythiae 5 parts, Fructus Xanthii 9 parts, Borneolum Syntheticum 2 parts, Pericarpium Citri Reticulatae 9 parts, Radix Platycodonis 8 parts.
3. the Chinese medicine preparation as described in claim 1 or 2, is characterized in that, described Chinese medicine preparation is capsule, granule or oral liquid.
4. the Chinese medicine preparation as described in claim 3, it is characterized in that, described Chinese medicine preparation is preferably oral liquid.
5. Chinese medicine preparation as claimed in claim 4, it is characterized in that, the preparation method of described oral liquid comprises following steps:
(1) according to aforesaid weight take above except Borneolum Syntheticum other Chinese medicine components be ground into coarse powder respectively; The water that first time adds medical material gross weight 6 times amount, soaks 4h, decocts 3h, filter while hot; Medicinal residues add the water of 4 times amount again, decoct 2h, filter while hot; Merge twice and decoct filtrate; When filtrate is concentrated into 75 DEG C, relative density is the extractum of 1.15 ~ 1.21, naturally cools to room temperature;
(2) in extractum, add Borneolum Syntheticum and the ethanol of ground recipe quantity, it is 45% ~ 65% that limit edged is stirred to alcohol content, then standing sedimentation 24 ~ 48h, filter, gained filtrate recycling ethanol, to without alcohol taste, then adds distilled water dosing, potassium sorbate with 0.1% regulates pH to 7.0 ~ 7.5, adding distil water is to enough again, with moist hear heat test sterilizing 30 minutes after fill, obtains oral solutions of the present invention.
6. the purposes of Chinese medicine preparation as claimed in claim 1 or 2 in the medicine of preparation treatment children with adenoid hypertrophy.
7. the purposes of Chinese medicine preparation as claimed in claim 1 or 2 in the medicine of preparation treatment qi and blood stagnation type children with adenoid hypertrophy.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108114262A (en) * | 2018-02-09 | 2018-06-05 | 福建中医药大学 | A kind of traditional Chinese medicine acupoint external preparation for treating adenoids and preparation method thereof |
| CN109106774A (en) * | 2018-10-22 | 2019-01-01 | 北京梅尔森医药技术开发有限公司 | A kind of Chinese medicine composition and its preparation method and application for treating adenoids and its complication |
| CN112057600A (en) * | 2020-10-26 | 2020-12-11 | 北京沃德中医药研究院 | Traditional Chinese medicine component for treating adenoid tonsil hypertrophy of children and preparation method thereof |
| CN114504644A (en) * | 2021-12-24 | 2022-05-17 | 北京大学第一医院 | Application of anti-IgE antibody in treatment of adenoid hypertrophy |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108114262A (en) * | 2018-02-09 | 2018-06-05 | 福建中医药大学 | A kind of traditional Chinese medicine acupoint external preparation for treating adenoids and preparation method thereof |
| CN108114262B (en) * | 2018-02-09 | 2021-08-27 | 福建中医药大学 | A Chinese medicinal acupoint topical preparation for treating adenoidal hypertrophy, and its preparation method |
| CN109106774A (en) * | 2018-10-22 | 2019-01-01 | 北京梅尔森医药技术开发有限公司 | A kind of Chinese medicine composition and its preparation method and application for treating adenoids and its complication |
| CN109106774B (en) * | 2018-10-22 | 2021-04-09 | 北京梅尔森医药技术开发有限公司 | Traditional Chinese medicine composition for treating adenoidal hypertrophy and complications thereof, and preparation method and application thereof |
| CN112057600A (en) * | 2020-10-26 | 2020-12-11 | 北京沃德中医药研究院 | Traditional Chinese medicine component for treating adenoid tonsil hypertrophy of children and preparation method thereof |
| CN114504644A (en) * | 2021-12-24 | 2022-05-17 | 北京大学第一医院 | Application of anti-IgE antibody in treatment of adenoid hypertrophy |
| CN114504644B (en) * | 2021-12-24 | 2024-02-13 | 北京大学第一医院 | Use of anti-IgE antibodies for the treatment of adenoid hypertrophy |
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Application publication date: 20151111 |