CN105030904A - Medical and edible dual-purpose Chinese herbal medicine composition for treating intestinal tract disease as well as preparation method and application of medical and edible dual-purpose Chinese herbal medicine composition - Google Patents
Medical and edible dual-purpose Chinese herbal medicine composition for treating intestinal tract disease as well as preparation method and application of medical and edible dual-purpose Chinese herbal medicine composition Download PDFInfo
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Abstract
The invention relates to a Chinese herbal medicine composition for treating an intestinal tract disease. The Chinese herbal medicine composition is prepared from the following traditional Chinese medicine materials: stephania tetrandra, radix cynanchi bungei, endothelium corneum gigeriae galli, duck's gizzard surface layer and cuttle bone. The invention further relates to a preparation method of the Chinese herbal medicine composition, and an application of the composition for preparing drugs and medicines for treating enterogastritis, gastric ulcer and gastric perforation. The product has obvious treatment effects for enterogastritis, gastric ulcer and gastric perforation while improving the state of nutrition of the patients suffering from intestinal tract diseases, and can be taken for a long term.
Description
Technical field
The present invention relates to the colourless transparent liquid through distillation extraction from natural Chinese medicinal herb, there is nourishing the stomach of regulating the flow of vital energy, promote that gastrointestinal function recovers, activate the regeneration of gastritis theca cell, be used for the treatment of gastritis, gastroenteritis, stomachache, gastric ulcer, Chinese medicine composition of the gastropathy such as gastric perforation and preparation method thereof, also relates to the application of said composition in preparation gastroenteropathy medicine.
Background technology
Gastroenteropathy is also called gastroenteritis, comprises gastric ulcer (as gastric perforation etc.) and duodenal ulcer etc.The disease of gastrointestinal system is as flatulence, dyspepsia reaction, and stomachache or gastric perforation person, also belong to the category of gastroenteropathy.Digestive system disease is refractory disease mostly, hidden attacking of falling ill, condition of illness dull pain, even if ill, patient Chang Buneng oneself examines and knows, how because of other diseases is sought medical advice or health examination time and be found.
Adopting the means of Chinese medicine to treat gastroenteropathy disease, is a channel extremely leaved for development, this is because Chinese medicine have mild in medicine property and, the feature such as applied widely, therefore as the effect having it original in gastroenteropathy treatment.
Summary of the invention
An object of the present invention is to provide a kind of Chinese medicine composition for the treatment of gastroenteropathy, said composition is prepared from by the raw material of Chinese medicine of following weight ratio:
Radix stephaniae tetrandrae 1-88 Radix Cynanchi Auriculati 30-170 stomach of chicken skin 30-170 duck's gizzard skin 30-170 Os Sepiae 30-150
Preferably, said composition is prepared from by the raw material of Chinese medicine of following weight ratio: Radix stephaniae tetrandrae 1-88 Radix Cynanchi Auriculati 30-170 stomach of chicken skin 30-170 duck's gizzard skin 30-170 Os Sepiae 30-150
Most preferably, said composition is prepared from by the raw material of Chinese medicine of following weight ratio:
Radix stephaniae tetrandrae 5 Radix Cynanchi Auriculati 30 duck's gizzard skin 15 stomach of chicken skin 15 Os Sepiae 30.
Chinese medicine composition of the present invention can make various types of pharmaceutical preparation according to actual needs, such as, make tablet, capsule, beverage, bag tea, cookies, oral liquid or injection etc., preferably but be not limited to oral liquid.In order to prepare these preparations, conventional pharmaceutically acceptable auxiliaries can be added as required in the present compositions, for the selection of adjuvant, those skilled in the art can carry out according to the requirement of dosage form, such as, when preparing oral liquid, sweeting agent, flavoring agent and antiseptic can be added in the compositions of the present invention.For the concrete selection of adjuvant, the present invention's specific restriction useless.
Another object of the present invention is to provide a kind of preparation method of the present composition, the method comprise clean, dry and above four taste raw material of Chinese medicine are ground into coarse powder, cross No. two sieves, put into the extraction pot of band distillator, add water 5-10 times amount, soaks 2-5 hour, stirs 2-5 time therebetween, each 10-20 minute, heating extraction 1-3 hour, collects distillate appropriate, places 8-12 hour under cold preservation, precipitation, filters.
Subsequently, according to the ordinary skill in the art, compositions of the present invention can be prepared into various dosage form.Such as get filtrate, if need to add flavoring agent and/or antiseptic, regulate pH value to 7.0, and adjust total amount, embedding, sterilizing with sodium hydroxide, packaging, obtains oral liquid of the present invention.
The present invention adopts the preparation technology of the way of distillation, and by the volatile ingredient straight run distillation in Radix stephaniae tetrandrae and all the other 4 taste medical materials out and get final product, technique is simple.So in fact the present invention is exactly the aqueous solution of various volatile ingredient.Preferably described water is distilled water.
It should be noted that, method of the present invention just a kind of preferred preparation technology but not
Be limited to this.The product prepared by the inventive method has good stability.
For many years, adopt Chinese medicine composition of the present invention, particularly oral liquid treatment gastroenteropathy, obtain good curative effect, have no any toxic and side effects.
Due to gastroenteropathy to be a dyspepsia be main disease, so adopt with Radix stephaniae tetrandrae ventilation for monarch in side, Radix Cynanchi Auriculati antiinflammatory is minister, and stomach of chicken skin, duck's gizzard skin is aid digestion is assistant.Again and the effect of Os Sepiae nourishing the stomach.
[composition] Radix stephaniae tetrandrae, Radix Cynanchi Auriculati, stomach of chicken skin etc.
[character] this product is achromaticity and clarification liquid, and gas is fragrant, mildly bitter flavor.
The regeneration of [function cures mainly] ventilation, antiinflammatory, promotion stomach functional rehabilitation, activation gastric ulcer place cell, is used for the treatment of the gastroenteropathy such as flatulence, gastroenteritis, gastric ulcer gastric perforation.
[usage and dosage] oral 10-30 milliliter, 2-3 time on the one or follow the doctor's advice.
Even after [untoward reaction] medication have dizzy sense.
[points for attention] 1, period in a medicine are forbidden share with other Chinese medicine.2, period in a medicine is forbidden share with antiallergic agent.3, pungent, the seafood food of period in a medicine fasting.4, as taken other medicines, please Ref Dr or pharmacist before using this product.
For this reason, another object of the present invention is to provide a kind of present composition at preparation treatment gastroenteritis, gastritis, gastric ulcer, the application in the medicines such as gastric perforation.
Accompanying drawing explanation
Accompanying drawing 1 is preparation technology's flow chart of the oral liquid of the Chinese medicine composition of invention.
Detailed description of the invention
Embodiment 1
Oral liquid:
Clean, dry raw material of Chinese medicine and consumption:
Radix stephaniae tetrandrae 1-88 Radix Cynanchi Auriculati 30-170 stomach of chicken skin 30-170 duck's gizzard skin 30-170 Os Sepiae 30-150
Method for making: above four taste raw material of Chinese medicine are ground into coarse powder, crosses No. two sieves, and put into the extraction pot of band distillator, add water 1600ml, soak 2 hours, stir 3 times therebetween, each 10 minutes, heating extraction 1 hour, collection distillate is appropriate, places 8-12 hour under cold preservation, precipitation, filters.
Get filtrate, regulate pH value to 7.0 with sodium hydroxide, and adjust total amount to 1000ml.Embedding, sterilizing, packaging, to obtain final product.
Character: this product is achromaticity and clarification liquid; Gas is fragrant, puckery, micro-hardship.
Differentiate: get this product 200ml, put in round-bottomed flask, connect condensing tube (should be short and small) heating and be distilled to boiling about 1 minute, when crystallization appears in inside pipe wall to be condensed, withdraw thermal source immediately, collect the crystallization of distillate (about 2-3ml) and condensing tube condensed on inner walls.
(1) crystallization taking precipitation is appropriate, adds ethanol and makes dissolving, and makes the solution of every 1ml containing 2.5mg, as need testing solution.According to ultraviolet-visible spectrophotometer method (China's coastal port annex VA) test, take ethanol as blank.Between wavelength 230-350nm, measure absorption curve, its absorption curve should be consistent with the absorption curve of Radix Ginseng reference substance solution (1ml is containing 2.5ml), should have a maximum absorption band at wavelength 289 ± 1nm place.
(2) getting this product distillate, according to ultraviolet visible spectrophotometry (China's coastal port annex VA) test, take water as blank.Measure absorption curve at the wavelength place of wavelength 250-350nm, at 277 ± 1nm place, a maximum absorption band should be had.
Check: relative density should be not less than 0.9 (China's coastal port annex VIIA).
PH value should be 5.5-7.5 (China's coastal port annex VIIG).
Other every regulations relevant under should meeting mixture item (China's coastal port annex IJ).
Usage and consumption: oral, a 10-30 milliliter, 2-3 time on the one, or follow the doctor's advice.
Embodiment 2
Antipyretic beverage:
Clean, dry raw material of Chinese medicine and consumption:
Radix stephaniae tetrandrae 1-88 Radix Cynanchi Auriculati 30-170 stomach of chicken skin 30-170 duck's gizzard skin 30-170 Os Sepiae 30-150 method for making: above Chinese medicine of the five flavours raw material powder is broken into coarse powder, cross No. two sieves, put into the extraction pot of band distillator, add water 16000ml, soak 2 hours, stir 3 times therebetween, each 10 minutes, heating extraction 1 hour, collection distillate is appropriate, place 8-12 hour under cold preservation, precipitation, filter.
Get filtrate, add suitable amount of sucrose and dissolve, regulate pH value to 7.0 with sodium hydroxide, and adjust total amount to 10000ml.Embedding, sterilizing, packaging, to obtain final product.
Embodiment 3
Capsule, pill, bag tea:
Clean, dry raw material of Chinese medicine and consumption:
Radix stephaniae tetrandrae 1-88 Radix Cynanchi Auriculati 30-170 stomach of chicken skin 30-170 duck's gizzard skin 30-170 Os Sepiae 30-150 method for making: above four taste raw material of Chinese medicine are ground into fine powder, crosses 120 mesh sieves, adds proper amount of sugar or sucrose adjuvant, put into the extraction pot of band distillator, add water 1600ml, soaks 2 hours, stirs 3 times therebetween, each 10 minutes, heating extraction 1 hour, collects concentrate appropriate, places 8-12 hour under cold preservation, precipitation, filters.Get concentrate and beat fine powder, or raw material is broken into fine powder, add appropriate amount of auxiliary materials.Encapsulated, dress tea-bag, pill, and other goods, sterilizing, packaging, to obtain final product.
Embodiment 4
Injection:
Clean, dry raw material of Chinese medicine and consumption:
Radix stephaniae tetrandrae 1-88 Radix Cynanchi Auriculati 30-170 stomach of chicken skin 30-170 duck's gizzard skin 30-170 wafts in sea Octopus ocellatus Gray 30-150 method for making: above four taste raw material of Chinese medicine are ground into coarse powder, cross No. two sieves, put into the extraction pot of band distillator, add water 1600ml, soak 2 hours, stir 3 times therebetween, each 10 minutes, heating extraction 1 hour, collection distillate is appropriate, place 8-12 hour under cold preservation, precipitation, filter.
Get filtrate, regulate pH value to 7.0 with sodium hydroxide, and adjust total amount to 1000ml.Embedding, sterilizing, packaging, to obtain final product.
Embodiment 5
Clinical trial:
1. gastroenteritis
Gastroenteritis patient 100 example, comprehensively examines or check from clinical examination and biopsy pathology three aspects; After a course for the treatment of of treatment, have 45 routine patients' recoveries from illness, 43 routine patients symptomatic obviously alleviate, and 12 routine patients do not have clear improvement; After two courses for the treatment of of treatment, have 48 routine patients' recoveries from illness, 46 routine patients symptomatic obviously alleviate, and 6 routine patients do not have clear improvement; After three courses for the treatment of of treatment, have 51 routine patients symptomatic obviously to fully recover, 47 routine patients improve; 2 routine patients do not have clear improvement..
2. gastric ulcer
Patients w ith peptic ulcer disease 100 example, from clinical symptoms, scope differs from two each side examinations; After a course for the treatment of of treatment, have 68 routine patients' recoveries from illness, 28 routine patients symptomatic obviously alleviate, and 4 routine patients do not improve; After two courses for the treatment of of treatment, have 78 routine patients' recoveries from illness, 22 routine patients symptomatic obviously alleviate, and 0 example is not improved; After three courses for the treatment of of treatment, 89 routine patients' recoveries from illness, 11 routine patients symptomatic obviously alleviate, and 0 example is not improved.
3. gastric perforation
Epigastrium pain is uncomfortable, and stool has black clot, and tongue tongue is white, and endoscopy two is respectively examined or check;
Gastric perforation patient 100 example, single from clinical observation: after a course for the treatment of of treatment, 16 routine patients' recoveries from illness, 84 routine patients symptomatic obviously alleviate, and 0 example is not improved; After treatment two each course for the treatment of, have 38 routine patients' recoveries from illness, 62 routine patients symptomatic obviously alleviate, and 0 example is not improved; After three courses for the treatment of, 100 example recoveries from illness.
Therapeutic Method:
The oral liquid group of Chinese medicine composition of the present invention: every day 2 times, each 1 30th is a course for the treatment of, and interval started for second course for the treatment of after 2 ~ 3 days, used 2-3 the course for the treatment of.
The oral liquid mixing group of Chinese medicine composition of the present invention: every day 2 times, each 1 30th is a course for the treatment of, and interval started for second course for the treatment of after 2 ~ 3 days, used 2-3 the course for the treatment of.To shake up rear oral when taking.
Matched group: the oral liquid not taking Chinese medicine composition of the present invention, only with treatment chronic gastritis, gastroenteritis or gastric ulcer, the conventional therapy medicated tea of gastric perforation.
Discuss: the oral liquid of Chinese medicine composition of the present invention is a kind of pure Chinese herbal and crude drugs preparations, it is the colourless transparent liquid through distillation extraction from natural Chinese medicinal herb, there is ventilation nourishing the stomach, anti-inflammatory analgetic, promotion are functional rehabilitation, activate the regeneration of gastric ulcer place cell, be used for the treatment of the diseases such as gastroenteritis, gastric ulcer, gastric perforation.
By oral liquid patients with gastric disease 400 example of observation with Chinese medicine composition of the present invention.Effectively pain relieving, hemostasis, facilitating digestion raising in various degree can be all had after taking this medicine.The oral liquid group total effective rate 99% of Chinese medicine composition of the present invention, the oral liquid mixed type group total effective rate 99% of Chinese medicine composition of the present invention.Coordinate original therapeutic scheme can improve the remission rate of gastropathy.Thus improve remission rate.The oral liquid use safety of Chinese medicine composition of the present invention, to have no side effect.
Embodiment 6
Model case exemplifies:
Case one: Yang: because long-term taking aspirin is too much before and after 1963, frequent gastrorrhagia, 1 6-7 time, through hospitalization, after to take Chinese herbal medicine two of the present invention course for the treatment of when gastrorrhagia, sb.'s illness took a favorable turn, hemorrhagely stopping, within 13 years, not appearing 1 blood to dying backward.
Case two: Lee: man: 23 years old, Normal University student, because gastric ulcer is very heavy, took prescription two of the present invention and return to one's perfect health the course for the treatment of.
Case three: Lee so-and-so: man, 70 years old, in July, 1985 was restive in Jinhua hospital gastrorrhagia, fecal blood 4 adds, and hematochrome drops to 2.5 grams of households and lifts middle preparation funeral affairs of going home, after take Chinese herb medicine of the present invention 2 days, sb.'s illness took a favorable turn, the 3rd day just can out-of-bed activity.
Case four: Cao: man, 33 years old.Because separating black stool, general weakness, prepare to go to the hospital treatment, after taking Chinese patent medicine of the present invention, within the 3rd day, find that stool the first half part is black, and the latter half is yellow, spirit takes a turn for the better, and has not just gone to the hospital.
Case five:, Lee: female, 24 years old, service man KTV, because of gastrorrhagia, all day have a stomachache, general weakness, in November, 2007 take the same day remove stomachache, fully recover with after three courses for the treatment of.
Case six: Cao, female, 65 years old, because of gastrorrhagia, in Jinhua City People's Hospital's treatment, more than 20 day haemophilia, descend notice of being critically ill for 3 times, prepare the treatment of Jinhua central hospital, take Chinese herb medicine of the present invention before transferring from one hospital to another 3 days, every day 4 times, assistant director is to Jinhua central hospital check result, blood is to stop, and hematochrome rises to 6.8 grams from original 3.1, and not being in hospital just directly leaves hospital has gone home to have had a rest.
Case seven: what so-and-so: man, 27 years old, service man KTV, because long-term gastropathy is had a stomachache, took two rehabilitations course for the treatment of in December, 2007, do not have stomachache.
Case eight: Yang: man, 38 years old, blue dish ornaments office worker, because stomachache is very heavy, took the prescription two of the present invention stomachache course for the treatment of and disappears.
Medicine of the present invention takes Chinese herbal medicine compound prescription of the present invention through routine patient up to a hundred (comprising gastroenteritis, gastric ulcer, gastric perforation etc.) patient, and reflection very well.
Embodiment 7
Acute toxicity test:
The oral liquid of Chinese medicine composition of the present invention is a kind of pure Chinese medicinal preparation, it is the colourless transparent liquid through distillation extraction from natural Chinese medicinal herb, there is the regeneration of ventilation nourishing the stomach, anti-inflammatory analgetic, promotion stomach functional rehabilitation, activation gastric ulcer place cell, be used for the treatment of the gastroenteropathy such as gastroenteritis, gastritis, gastric ulcer and gastric perforation.
Therefore, carried out acute toxicity test in mice to this medicine, its acute toxicity test is reported as follows:
Choose NIH kind mice 20,
half and half, body weight is 23.52 ± 2.20g (X ± S), by the dosage gastric infusion of 40ml/kg, one day twice, observes seven, phenomenon without exception, and without dead, body weight increases to 27.57 ± 2.61g (X ± S), comparatively weightening finish 17.22% before administration.
The oral liquid clinical medicine dose of Chinese medicine composition of the present invention is 5ml × 2=10ml every day, adult's body weight is by 60kg, the oral dose of being then grown up is 10ml/60kg=0.167ml/kg, and it is 40 × 2=80ml/kg that mice is daily measured, and the 80/0.167=480 of suitable people's consumption doubly.
The oral liquid formulations of Chinese medicine composition of the present invention is oral ampulla, selects NIH kind mice 10, and with the every dosage tail vein injection only of 0.5ml, 8-10 at the uniform velocity injects second, observes 72 hours, phenomenon without exception, without dead.
Result of the test shows: the oral liquid toxicity of Chinese medicine composition of the present invention is less.
Embodiment 8
Long term toxicity test:
The oral liquid of Chinese medicine composition of the present invention is a kind of pure Chinese medicinal preparation, it is the colourless transparent liquid through distillation extraction from natural Chinese medicinal herb, there is ventilation nourishing the stomach, anti-inflammatory analgetic, promotion are functional rehabilitation, activate the regeneration of gastric ulcer place cell, be used for the treatment of the diseases such as gastroenteritis, gastritis, gastric ulcer, gastric perforation.Test report is as follows:
Materials and methods
The Wistar rat 60 of experimental animal: 7-8 health in age in week, male and female half and half, are provided by Wenzhou Medical College's Experimental Animal Center.Observe one week before test, adopt randomized blocks that rat is divided into three groups, often organize 20, male and female half and half, sub-cage rearing.Periodic logging rats eating amount, freely drinks water.Claim a body weight weekly.
Tested material and dosage: " oral liquid of Chinese medicine composition of the present invention " are plurality of Chinese distillation extraction, the supernatant liquid of purification.
Dosage group is the requirement by acute toxicity testing result and new Chinese medicine toxicologic study guide, if height two dosage groups and a matched group.High dose is 1200g/kg, and be equivalent to 70 times of clinical application amount, low dose group is 500g/kg, is equivalent to 30 times of clinical application amount.
Route of administration and method: adopt administration by gavage.Gavage volume presses the not even depth administration such as capacity such as grade of 1% of body weight.Every day 1 time, 6 days weekly, amount to 8 weeks.Body weight change adjustment dosage is pressed weekly during administration.
Observation index:
Ordinary circumstance: observe outward appearance sign every day, behavioral activity, urine excrement situation, food-intake.Weigh weekly and observe change.
Hematological examination: often organize and get 10 rats (male and female half and half) at random, before administration, after administration the 4th week and the 8th week, at tail venous blood sampling, the indexs such as erythrocyte, leukocyte classification, platelet, reticulocyte and content of hemoglobin are tested by " national Clinical Laboratory rule of operation " requirement.
Blood biochemical analysis checks: test proceeds to the 4th week and the 8th week, take a blood sample in thigh blood vessel, measure serum alanine aminotransferase (ALT), total bilirubin (T--BIL), blood urea nitrogen (BUN) and creatinine (CRE) four indices.
Rat is dissected and histopathologic examination: experiment terminates, often organize and get 10 rats (male and female half and half), thigh blood vessel sacrificed by exsanguination, conventional dissection, observe the mode of appearance of each internal organs, color etc., and the internal organs such as the heart, liver, spleen, lung, kidney, brain are weighed, calculate the percentage ratio of itself and body weight, i.e. organ coefficient.Then pathology method process routinely, does the histopathologic examination of the heart, liver, spleen, lung, kidney, brain and femur.
Statistical procedures: adopt T inspection and F inspection.Data machine process as calculated.
Result:
General state and body weight change: during administration, each treated animal general state, movable normal, no abnormality seen reacts.Administration group is substantially close with matched group food-intake.Administration group and matched group body weight growth trend basically identical, illustrate that long term administration has no significant effect growth of animal.Male Mus or female Mus each administration group weight gain value compared with matched group, no significant difference (P > 0.05).
Hematological indices: rat hemogram check result lists in table 1,2,3.Found out by table 1 and table 2, " oral liquid of Chinese medicine composition of the present invention " height, end dosage group erythrocyte, platelet, platelet and content of hemoglobin before administration, after administration 4 weeks and 8 weeks, compared with matched group, P > 0.05, illustrates that medicine has no significant effect above-mentioned each index.
Blood biochemical analysis index: test proceeds to the 4th week and the 8th week, take a blood sample in thigh blood vessel, measure serum alanine aminotransferase (ALT), total bilirubin (T--BIL), blood urea nitrogen (BUN) and creatinine (CRE) four indices the results are shown in table 3.
Organ weights: respectively organize the organ weights such as the heart, liver, spleen, lung, kidney, brain and organ coefficient lists in table 4.
Histopathologic examination: off-test, rat is dissected, and does not find the obvious change of the organs such as the heart, liver, spleen, lung, kidney, brain.Histopathologic examination does not also find that there is pathological change, shows long term administration to each organs and tissues without obvious damage.
Brief summary:
Within continuous 8 weeks, pour into " oral liquid of herbal composite of the present invention " to rat oral, dosage is 70 times and 30 times of quantity, and rat general state is good, performance without exception, and each group bodyweight difference, without significance, has no significant effect rat normal growth.
Administration in continuous 8 weeks, rat reticulocyte significantly increases (table 2), learns the change of other indexs of liquid not significantly (table 4), illustrates that " oral liquid of Chinese medicine composition of the present invention " can improve hemopoietic function.
" oral liquid of Chinese medicine composition of the present invention " long term toxicity test result shows, finds no pathological change (table 1).
Above result of the test shows, " oral liquid of Chinese medicine composition of the present invention " life-time service, without overt toxicity, is safer Chinese medicine preparation.
Table 1, " oral liquid of Chinese medicine composition of the present invention " long term toxicity test hemogram result (X ± S)
Table 2, " oral liquid of Chinese medicine composition of the present invention " are on the impact (%, X ± S) of reticulocyte
| Group | Number of animals | Before administration | After administration 4 weeks | After administration 8 weeks | P |
| Contrast | 10 | 2.05±1.13 | 1.40±0.69 | 2.18±1.34 | |
| Low dosage | 10 | 1.93±1.17 | 2.13±1.07 | 6.75±1.35 | ＜0.01 |
| High dose | 10 | 2.11±1.12 | 2.21±0.91 | 7.07±1.91 | ＜0.01 |
| P | ＞0.05 | ＞0.05 | ＞0.05 |
Table 3, differential blood count result (%, X ± S)
Table 4, blood biochemical analysis index determining result (X ± S)
Table 5, each group organ coefficient compare (X ± S)
Embodiment 9
The stability of product of the present invention: carry out repeatedly stability test for various product of the present invention.Test comprises high temperature and accelerates and room temperature placement.All show that product of the present invention has good stability.The oral liquid of one of product of the present invention embodiment 1 is shown at the placement steadiness of 18 months in table 8.
Above embodiments of the invention have been described in detail, but described content being only preferred embodiment of the present invention, can not being considered to for limiting practical range of the present invention.All equalizations done according to the present patent application scope change and improve, and all should still belong within patent covering scope of the present invention.
Claims (2)
1. control the Chinese herbal medicine of chronic gastritis, gastric ulcer, gastric perforation for one kind, its composition comprises: Radix stephaniae tetrandrae, Radix Cynanchi Auriculati, stomach of chicken skin, duck's gizzard skin, Os Sepiae, its feature: the various Chinese medicine ratio of weight and number of numeral of Radix stephaniae tetrandrae 1-88, Radix Cynanchi Auriculati 30-170, stomach of chicken skin 30-170, duck's gizzard skin 30-170, more than Os Sepiae 30-150, powder smalls is packed altogether.
2. treat the herbal composite of gastroenteropathy and the method for preparation thereof for one kind, by Radix stephaniae tetrandrae, Radix Cynanchi Auriculati, Endothelium Corneum Gigeriae Galli, Os Sepiae, it is characterized in that: each component by weight percentage is, Radix stephaniae tetrandrae 5%, Radix Cynanchi Auriculati 32%, stomach of chicken skin 20%, duck's gizzard skin 10%, Os Sepiae 33%.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1676146A (en) * | 2004-03-29 | 2005-10-05 | 刘尚东 | Medicine for treating gastric ulcer |
| CN101259196A (en) * | 2008-04-14 | 2008-09-10 | 张桂松 | Chinese medicinal composition for treating gastric ulcer |
| CN104547560A (en) * | 2014-12-08 | 2015-04-29 | 张仁勇 | Medicine for treating gastric diseases and preparation method thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1676146A (en) * | 2004-03-29 | 2005-10-05 | 刘尚东 | Medicine for treating gastric ulcer |
| CN101259196A (en) * | 2008-04-14 | 2008-09-10 | 张桂松 | Chinese medicinal composition for treating gastric ulcer |
| CN104547560A (en) * | 2014-12-08 | 2015-04-29 | 张仁勇 | Medicine for treating gastric diseases and preparation method thereof |
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