CN105012059A - Biodegradable drug stent - Google Patents
Biodegradable drug stent Download PDFInfo
- Publication number
- CN105012059A CN105012059A CN201410410095.4A CN201410410095A CN105012059A CN 105012059 A CN105012059 A CN 105012059A CN 201410410095 A CN201410410095 A CN 201410410095A CN 105012059 A CN105012059 A CN 105012059A
- Authority
- CN
- China
- Prior art keywords
- annulus
- crest
- rhombus
- biodegradable drug
- shaped structure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a biodegradable drug stent. The stent is tubular and comprises a plurality of first circular rings which are arranged longitudinally, each first circular ring is in the sinusoidal waveform in the circumferential direction, and the plurality of first circular rings are aligned longitudinally; a second circular ring is arranged between every two longitudinally adjacent first circular rings, each second circular ring is formed by connecting a plurality of rhombuses in a surrounding mode in the circumferential direction, and two connecting arms are connected between the wave crests, close to the second circular ring longitudinally, of the two first circular rings and the second circular ring respectively, so that the two first circular rings, the second circular ring and the plurality of connecting arms form a plurality of honeycomb structures and a plurality of diamond-shaped structures; each honeycomb structure comprises two diamond-shaped structures; after the stent is expanded, the plurality of honeycomb structures and diamond-shaped structures are linked mutually to form a stable supporting structure, so that the radial supporting force of the stent is strengthened.
Description
Technical field
The present invention relates to support and insert technology, particularly relate to a kind of biodegradable drug stent.
Background technology
Clinically, the basic demand of human body official jargon implantation instrument is comprised: after apparatus implanted human body official jargon organ, the mechanical support power that implanted organ is enough can not only be provided, can evenly discharge in medicine to organism in wall of the lumen, effectively to control the foreign body reaction caused by implanting prosthetic by Huan Man ﹑ Chi Xu ﹑ again.
Medicament-release blood vessel stent is exactly a kind of implanting prosthetic meeting above standard.Support is plain cylindrical form device, and tube chamber can be kept unobstructed, sometimes can blood vessel dilating or other dissect tube chamber as ureter, bile duct.The official jargon stenosis disease that support causes through being usually used in vascular atherosclerosis.Luminal stenosis refers to that the tube chamber in body narrows or tightens.In the middle of this treatment means, support plays a supportive role in tube chamber in case hemostatic tube shaping Vascular Restenosis after Balloom occurs.It is narrow that restenosis refers to that vessel lumen or cardiac valve again occur after carrying out the successful treatment such as such as balloon expandable, stenter to implant, valvoplasty.
Support can be made of a variety of materials, and comprises metal and polymeric material.In polymer support, the many advantages of biodegradable polymer stent tool: first, after biodegradable stent implants official jargon, after completing the Kuo Zhang ﹑ support to narrow official jargon, by body automatic absorption, thus can avoid by the advanced thrombus caused in non-degradable support prolonged stay body and restenosis sequela.Secondly, the medicine suppressing vascular restenosis can be housed in degradable polymer body, and after stenter to implant, medicine is slow releasing with the degraded of support, thus the mode of permanently effective control vascular restenosis.In conventional metals drug stent, medicine only can be sprayed at the surface of metal rack, and discharges complete in after stenter to implant 28 days.
But the subject matter that polymeric material support exists at present is that the support force of support is low, can not meet the needs of clinical patients with coronary artery disease completely.For addressing this problem, apply for before the applicant that Chinese Patent Application No. is the patent of invention of 201280036466.6, it is disclosed that a kind of particular design of biodegradable drug stent, this support in a tubular form, comprise multiple the first annulus longitudinally arranged, this first annulus is sinusoidal wave form at circumferencial direction, and multiple first annulus longitudinally aligns; Wherein, connected by the linking arm of S shape between the crest of the correspondence that two adjacent the first annulus are longitudinally close to each other, make the linking arm of two the first annulus and many S shapes form multiple honeycomb shaped structure; Be provided with the second annulus between two the first annulus, this second annulus also in sinusoidal wave form, makes the place that the second annulus and the linking arm of S shape intersect form X-shaped structure at circumferencial direction.
Wherein, the weak point of this biodegradable drug stent is: between the linking arm of two S shapes of honeycomb shaped structure, only has a syndeton of the second annulus, therefore when expanding, support may not provide enough radial support power, so still need to improve its structure.
Summary of the invention
The object of the invention is to provide a kind of biodegradable drug stent for the deficiencies in the prior art, it by strengthening the stability after honeycomb shaped structure expansion, thus strengthens the radial support power of support, solves the problem.
To achieve these goals, the present invention is by the following technical solutions:
A kind of biodegradable drug stent, in a tubular form, comprise multiple the first annulus longitudinally arranged, this first annulus is sinusoidal wave form at circumferencial direction to this support, and multiple first annulus longitudinally aligns; The second annulus is provided with between two longitudinally adjacent the first annulus, this second annulus at circumferencial direction by multiple rhombus around connecting and composing, and two the first annulus are longitudinally near being all connected with a linking arm between the crest of this second annulus and the second annulus, two the first annulus and the second annulus and many linking arms are made to form multiple honeycomb shaped structure and multiple diamond structure, and each honeycomb shaped structure comprises two diamond structures, these two diamond structures are symmetrical arranged with the cross central line of honeycomb shaped structure.
Wherein, linking arm one end is connected with the crest of the first annulus, the mid point on the limit of the rhombus of the second annulus that the linking arm other end is corresponding with the crest of this first annulus connects, make a rhombus of the crest of four the first annulus and the second annulus and four linking arms form a honeycomb shaped structure, and the half on a rhombus two limits of the crest of two the first annulus and the second annulus and two linking arms form a diamond structure.
Wherein, the horizontal catercorner length of the rhombus of the second annulus equals two sinusoidal wave wavelength of the first annulus, and longitudinal catercorner length of the rhombus of the second annulus is less than the longitudinal pitch of two first annulus.
Wherein, linking arm one end is connected with the crest of the first annulus, longitudinal summit of the rhombus of the second annulus that the linking arm other end is corresponding with the crest of this first annulus connects, the X-shaped structure that two rhombuses of the crest of four the first annulus and second annulus are connected to form and four linking arms form a honeycomb shaped structure, and two rhombuses of the crest of two the first annulus and the second annulus and two linking arms form a diamond structure.
Wherein, the horizontal catercorner length of the rhombus of the second annulus equals a sinusoidal wave wavelength of the first annulus, and longitudinal catercorner length of the rhombus of the second annulus is less than the longitudinal pitch of two first annulus.
Wherein, this honeycomb shaped structure a pair linking arm is along the circumferential direction bracket shape.
Wherein, the first annulus is made up of the ripple of multiple V-arrangement, and the ripple of this V-arrangement has crest and is positioned at the swing wall of these crest both sides.
Wherein, this support is made up of polylactic acid.
Wherein, this support at least has an identification marking of adding or embedding.
Wherein, this identification marking is roentgenopaque pointing object or tablet.
Beneficial effect of the present invention is: the present invention first annulus and the second annulus and many linking arms form multiple honeycomb shaped structure and multiple diamond structure, and each honeycomb shaped structure comprises two diamond structures, after stent-expansion, the interactive link of multiple honeycomb shaped structure and diamond structure, form a firm supporting construction, thus strengthen the radial support power of support.
Accompanying drawing explanation
Patent application document comprises at least one color and performs picture.If official demands and provide the copy that necessary expenses geld can provide this patent or Patent Application Publication coloured picture picture.
Fig. 1 is the panorama sketch of the support of the embodiment of the present invention 1 of the automatic Microcomputer Drawing Software on Drawing of two dimension.
Fig. 2 is the plan view of the first annulus of the support of the embodiment of the present invention 1 of the automatic Microcomputer Drawing Software on Drawing of two dimension.
Fig. 3 is the second annulus of support and the plan view of linking arm of the embodiment of the present invention 1 of the automatic Microcomputer Drawing Software on Drawing of two dimension.
Fig. 4 is the plan view of the honeycomb shaped structure of the support of the embodiment of the present invention 1 of the automatic Microcomputer Drawing Software on Drawing of two dimension.
Fig. 5 is the axonometric chart after the stent-expansion of the embodiment of the present invention 1 that computer analog illustration is described.
Fig. 6 is the photo of support on dilating sacculus of the embodiment of the present invention 1.
Fig. 7 is the X-ray image figure of stenter to implant pig arteria coronaria after 6 months of the embodiment of the present invention 1.
Fig. 8 is the ivus image display figure of stenter to implant Sanguis sus domestica pipe after 6 months of the embodiment of the present invention 1.
Fig. 9 is the pathological staining picture of stenter to implant pig arteria coronaria after 6 months of the embodiment of the present invention 1.
Figure 10 is the axonometric chart after the stent-expansion of the embodiment of the present invention 2 that computer analog illustration is described.
Detailed description of the invention
In order to describe technical scheme of the present invention in detail, below in conjunction with the accompanying drawing of the embodiment of the present invention, clear, complete description is carried out to the technical scheme of the embodiment of the present invention.Obviously, described embodiment is a part of embodiment of the present invention, instead of whole embodiments.Based on described embodiments of the invention, the every other embodiment that those of ordinary skill in the art obtain under without the need to the prerequisite of creative work, all belongs to the scope of protection of the invention.
Embodiment 1
In one embodiment, Biodegradable scaffold of the present invention has radial support power and the geometrical stability of increase.Fig. 1 ~ 6 depict the pattern of an embodiment medium-height trestle 100.Support 100 in a tubular form, especially support 100 expand after, as shown in Figure 5 and Figure 6, make support 100 implant expansion after can support blood vessels.
In Fig. 1 ~ 4, support 100 is with plan representation, so that the view of support can clearly present.
It is sinusoidal wave form at circumferencial direction that support 100 comprises multiple the first annulus 101, first annulus 101 longitudinally arranged, and multiple first annulus 101 longitudinally aligns.As shown in Figure 2, preferably, the first annulus 101 is made up of the ripple 10 of multiple V-arrangement, and namely multiple transversely arranged V-arrangement ripple 10 is formed, and the ripple 10 of V-arrangement has crest 11 and is positioned at the swing wall 12 of crest 11 both sides.
Be provided with between two longitudinally adjacent the first annulus 101 second annulus 102, second annulus 102 at circumferencial direction by multiple rhombus around connecting and composing.And two the first annulus 101 are longitudinally near between the crest of the second annulus 102 (crest 11 as marked in Fig. 1) and the second annulus 102, all be connected with a linking arm 13, namely each crest of the first annulus 101 is all connected with the second annulus 102 by a corresponding linking arm 13, makes two the first annulus 101 and the second annulus 102 and many linking arms 13 form multiple honeycomb shaped structure 103 and multiple diamond structure 105.And each honeycomb shaped structure 103 comprises two diamond structures, as shown in Figure 4, two diamond structures 105 are symmetrical arranged with the cross central line of honeycomb shaped structure 103.
Preferably, as shown in Figures 2 and 3, the horizontal catercorner length (a) of the rhombus of the second annulus 102 equals two sinusoidal wave wavelength (c) of the first annulus 101, longitudinal catercorner length (b) of the rhombus of the second annulus 102 is less than the longitudinal pitch of two first annulus 101, second annulus 102 is placed between two first corresponding annulus 101 better, makes honeycomb shaped structure 103 more stable.
In the present embodiment, as shown in Figure 1 and Figure 4, linking arm 13 one end is connected with the crest 11 of the first annulus 101, the mid point 14 on the limit of the rhombus of the second annulus 102 that linking arm 13 other end is corresponding with the crest 11 of the first annulus 101 connects, the crest 11 of four the first annulus 101 and a rhombus of the second annulus 102 and four linking arms 13 is made to form the half on the crest 11 of a honeycomb shaped structure 103, two the first annulus and a rhombus two limits of the second annulus 102 and two linking arms 13 form a diamond structure 105.This structure, make the rhombus of the second annulus 102 become syndeton between linking arm 13, longitudinal summit 15 of the rhombus of the second annulus 102 is just positioned at the centre of two crests 11, enhances structural stability, can strengthen the radial support power of support.And by X-shaped anatomical connectivity between two honeycomb shaped structure 103, make between honeycomb shaped structure 103 stable equally.
Preferably, honeycomb shaped structure 103 a pair linking arm 13 is along the circumferential direction in bracket shape, and as a pair linking arm 13 marked in Fig. 4, the angle that under a pair linking arm 13 can be held, the longitudinal direction of the rhombus of the second annulus 102 is protruded, structure is more stable.
Support 100 of the present invention is made up of polymeric material, and this material need comprise decomposition group can have the good compatibility with surrounding tissue, liquid (as blood vessel).Polymeric material armarium need decompose slowly avoid causing restenosis organize over loading or inflammatory reaction.Such as: support 100 of the present invention can be made up of polylactic acid.
Support 100 of the present invention at least has additional or an embed identification marking 104, identification marking 104 can be roentgenopaque pointing object or tablet, make roentgenopaque pointing object or tablet can be attached to the surface of support 100 or inlay wherein, to reach the object detecting or identify support 100 after the implantation.
Fig. 5 illustrates the state after support 100 expansion.
Fig. 6 illustrates the form of support 100 on dilating sacculus, after sacculus is withdrawn from, namely as shown in Figure 5.
Fig. 7 illustrates support 100 and implants the X-ray image figure of pig arteria coronaria after 6 months, and the blood vessel wall that display is implanted is smooth, without any angiostenosis mode.
Fig. 8 illustrates support 100 and implants the ivus image display figure of Sanguis sus domestica pipe after 6 months, and the support that display is implanted struts, completely without any retraction.
Fig. 9 illustrates the pathological section that support 100 inserts latter 6 months, confirms: support struts fabulous, occurs without phenomenons such as retraction, fractures.
Embodiment 2
As shown in Figure 10, the present embodiment is with the difference of embodiment 1: linking arm 13 one end is connected with the crest 11 of the first annulus 101, longitudinal summit 15 of the rhombus of the second annulus 102 that linking arm 13 other end is corresponding with the crest 11 of the first annulus 101 connects, the X-shaped structure that the crest 11 of four the first annulus 101 and two rhombuses of second annulus 102 are connected to form and four linking arms 13 form a honeycomb shaped structure 103, and one side of the crest 11 of two the first annulus 101 and two rhombuses of the second annulus 102 and two linking arms 13 form a diamond structure 105.This structure, makes the X-shaped structure of the second annulus 102 become syndeton between linking arm 13, enhances structural stability, can strengthen the radial support power of support.
Preferably, the horizontal catercorner length of the rhombus of the second annulus 102 equals a sinusoidal wave wavelength of the first annulus 101, longitudinal catercorner length of the rhombus of the second annulus 102 is less than the longitudinal pitch of two first annulus 101, second annulus 102 is placed between two first corresponding annulus 101 better, makes honeycomb shaped structure 103 more stable.
Finally should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention; but not limiting the scope of the invention; although done to explain to the present invention with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; technical scheme of the present invention is modified or equivalent replacement, all belong to protection scope of the present invention.
Claims (10)
1. a biodegradable drug stent, in a tubular form, comprise multiple the first annulus longitudinally arranged, this first annulus is sinusoidal wave form at circumferencial direction to this support, and multiple first annulus longitudinally aligns; It is characterized in that: between two longitudinally adjacent the first annulus, be provided with the second annulus, this second annulus at circumferencial direction by multiple rhombus around connecting and composing, and two the first annulus are longitudinally near being all connected with a linking arm between the crest of this second annulus and the second annulus, two the first annulus and the second annulus and many linking arms are made to form multiple honeycomb shaped structure and multiple diamond structure, and each honeycomb shaped structure comprises two diamond structures, these two diamond structures are symmetrical arranged with the cross central line of honeycomb shaped structure.
2. biodegradable drug stent according to claim 1, it is characterized in that: linking arm one end is connected with the crest of the first annulus, the mid point on the limit of the rhombus of the second annulus that the linking arm other end is corresponding with the crest of this first annulus connects, make a rhombus of the crest of four the first annulus and the second annulus and four linking arms form a honeycomb shaped structure, and the half on a rhombus two limits of the crest of two the first annulus and the second annulus and two linking arms form a diamond structure.
3. biodegradable drug stent according to claim 2, it is characterized in that: the horizontal catercorner length of the rhombus of the second annulus equals two sinusoidal wave wavelength of the first annulus, and longitudinal catercorner length of the rhombus of the second annulus is less than the longitudinal pitch of two first annulus.
4. biodegradable drug stent according to claim 1, it is characterized in that: linking arm one end is connected with the crest of the first annulus, longitudinal summit of the rhombus of the second annulus that the linking arm other end is corresponding with the crest of this first annulus connects, the X-shaped structure that two rhombuses of the crest of four the first annulus and second annulus are connected to form and four linking arms form a honeycomb shaped structure, and two rhombuses of the crest of two the first annulus and the second annulus and two linking arms form a diamond structure.
5. biodegradable drug stent according to claim 4, it is characterized in that: the horizontal catercorner length of the rhombus of the second annulus equals a sinusoidal wave wavelength of the first annulus, and longitudinal catercorner length of the rhombus of the second annulus is less than the longitudinal pitch of two first annulus.
6. the biodegradable drug stent according to claim 2 or 4, is characterized in that: this honeycomb shaped structure a pair linking arm is along the circumferential direction bracket shape.
7. the biodegradable drug stent according to claim 2 or 4, is characterized in that: the first annulus is made up of the ripple of multiple V-arrangement, and the ripple of this V-arrangement has crest and is positioned at the swing wall of these crest both sides.
8. the biodegradable drug stent according to claim 2 or 4, is characterized in that: this support is made up of polylactic acid.
9. the biodegradable drug stent according to claim 2 or 4, is characterized in that: this support at least has additional or an embed identification marking.
10. biodegradable drug stent according to claim 9, is characterized in that: this identification marking is roentgenopaque pointing object or tablet.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410410095.4A CN105012059B (en) | 2014-08-19 | 2014-08-19 | Biodegradable drug stent |
| PCT/CN2014/092641 WO2016026235A1 (en) | 2014-08-19 | 2014-12-01 | Biodegradable drug stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410410095.4A CN105012059B (en) | 2014-08-19 | 2014-08-19 | Biodegradable drug stent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105012059A true CN105012059A (en) | 2015-11-04 |
| CN105012059B CN105012059B (en) | 2017-02-15 |
Family
ID=54402621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410410095.4A Active CN105012059B (en) | 2014-08-19 | 2014-08-19 | Biodegradable drug stent |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN105012059B (en) |
| WO (1) | WO2016026235A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109124838A (en) * | 2018-08-24 | 2019-01-04 | 四川大学 | V-arrangement degradable biological frame |
| WO2019096159A1 (en) * | 2017-11-17 | 2019-05-23 | 杭州唯强医疗科技有限公司 | Peripheral endovascular stent |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1029517A2 (en) * | 1999-01-14 | 2000-08-23 | Medtronic Inc. | Staggered endoluminal stent |
| WO2005051238A1 (en) * | 2003-11-27 | 2005-06-09 | Forschungszentrum Karlsruhe Gmbh | Compression sleeve |
| US7500988B1 (en) * | 2000-11-16 | 2009-03-10 | Cordis Corporation | Stent for use in a stent graft |
| CN101732116A (en) * | 2008-11-15 | 2010-06-16 | 微创医疗器械(上海)有限公司 | Intravascular stent used for repairing lesion blood vessel |
| CN105682614A (en) * | 2014-01-28 | 2016-06-15 | 日本来富恩株式会社 | Stent |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19717475C1 (en) * | 1997-04-25 | 1998-09-03 | Heraeus Gmbh W C | Radially expandable support structure or stent for tubular vessel in body |
| US6264685B1 (en) * | 1999-07-06 | 2001-07-24 | Datascope Investment Corp. | Flexible high radial strength stent |
| US20030074051A1 (en) * | 2001-10-16 | 2003-04-17 | Kirsten Freislinger Luehrs | Flexible stent |
| US8926688B2 (en) * | 2008-01-11 | 2015-01-06 | W. L. Gore & Assoc. Inc. | Stent having adjacent elements connected by flexible webs |
| CN103930074B (en) * | 2011-05-22 | 2016-10-12 | 东莞天天向上医疗科技有限公司 | A kind of particular design of biodegradable drug stent |
| CN204169960U (en) * | 2014-08-19 | 2015-02-25 | 东莞天天向上医疗科技有限公司 | A kind of biodegradable drug stent |
-
2014
- 2014-08-19 CN CN201410410095.4A patent/CN105012059B/en active Active
- 2014-12-01 WO PCT/CN2014/092641 patent/WO2016026235A1/en active Application Filing
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1029517A2 (en) * | 1999-01-14 | 2000-08-23 | Medtronic Inc. | Staggered endoluminal stent |
| US7500988B1 (en) * | 2000-11-16 | 2009-03-10 | Cordis Corporation | Stent for use in a stent graft |
| WO2005051238A1 (en) * | 2003-11-27 | 2005-06-09 | Forschungszentrum Karlsruhe Gmbh | Compression sleeve |
| CN101732116A (en) * | 2008-11-15 | 2010-06-16 | 微创医疗器械(上海)有限公司 | Intravascular stent used for repairing lesion blood vessel |
| CN105682614A (en) * | 2014-01-28 | 2016-06-15 | 日本来富恩株式会社 | Stent |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019096159A1 (en) * | 2017-11-17 | 2019-05-23 | 杭州唯强医疗科技有限公司 | Peripheral endovascular stent |
| CN109124838A (en) * | 2018-08-24 | 2019-01-04 | 四川大学 | V-arrangement degradable biological frame |
| CN109124838B (en) * | 2018-08-24 | 2024-01-30 | 四川大学 | V-shaped degradable biological rack |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016026235A1 (en) | 2016-02-25 |
| CN105012059B (en) | 2017-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230042467A1 (en) | Absorbable intravascular devices that shorten upon expansion creating space for vascular movement | |
| US11234844B2 (en) | Multi-element bioresorbable intravascular stent | |
| US20230233344A1 (en) | Radially rigid and longitudinally flexible multi-element intravascular stent | |
| CN104287876B (en) | Grid | |
| US20090163989A1 (en) | Balloon expandable bioabsorbable stent with a single stress concentration region interconnecting adjacent struts | |
| CN102068331A (en) | Bifurcate blood vessel stent | |
| CN106137484A (en) | A kind of self-expansion type conical blood vessel support | |
| CN106691647B (en) | A kind of biodegradable metals intravascular stent and its application | |
| CN105012059A (en) | Biodegradable drug stent | |
| CN204618497U (en) | A kind of Biodegradable scaffold | |
| CN204169960U (en) | A kind of biodegradable drug stent | |
| CN105769398B (en) | Biodegradable vascular scaffold based on polyhedron deformation mechanism | |
| EP3449878A1 (en) | Vascular stent, preparation method therefor, and application thereof | |
| US20220142799A1 (en) | Absorbable intravascular devices that exhibit their greatest radial strength at their nominal diameters | |
| KR20060096025A (en) | Stent | |
| CN111772892A (en) | Magnesium alloy degradable stent applied to bent diseased cerebral vessels | |
| CN107088113A (en) | A kind of complicated brace rod intravascular stent | |
| KR100809865B1 (en) | Stent | |
| CN209269996U (en) | A kind of biological absorbable support of particle packaging medicine | |
| CN102657564B (en) | Biodegradable vascular scaffold | |
| CN104814821A (en) | Medicine carrying intravascular stent based on nano medicine carrier | |
| CN117717446A (en) | Vascular implant | |
| CN204698767U (en) | A kind of medicine carrying intravascular stent based on nano-medicament carrier | |
| CN103565565A (en) | Intra-hepatic bile duct support |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |