CN105004868B - A kind of multichannel thrombelastogram instrument and using method - Google Patents
A kind of multichannel thrombelastogram instrument and using method Download PDFInfo
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Abstract
The present invention relates to blood sample technical field of measurement and test, disclose a kind of multichannel thrombelastogram instrument, it includes data and signal processing module and the data acquisition module with described data with signal processing module interconnection, temperature control modules, motion-control module, level module and communication module, described data acquisition module connects multiple measurement module, described temperature control modules connects warm-up block and multiple heating module, described motion-control module connects loading module, Unload module, test module, turn module and reseting module, described communication module is also associated with passage expansion module, present invention also offers a kind of using method utilizing multichannel thrombelastogram instrument described above.The present invention can carry out passage extension the most flexibly, and can shorten the detection cycle, simplifies operating process, improves the intellectuality of instrument and integrated level, can accomplish multi-model interconnection, wireless interconnected simultaneously.
Description
Technical field
The present invention relates to blood sample technical field of measurement and test, particularly relate to a kind of for detecting blood sample
Multichannel thrombelastogram instrument and using method.
Background technology
Thrombelastogram instrument is a non-invasive type diagnostic instruments, assists clinicist to clinical disease
People's blood coagulation situation makes accurately judgement.By blood sample coagulation process being monitored, testing, divide
Analysis, the blood sample coagulation parameters information drawn, this patient's blood coagulation situation is made qualitative and quantitative pre-
Survey.Blood coagulation assessment is usually used in making prediction clinical condition, such as postoperative hemorrhage, heart outer operation
In or postoperative thrombosis, organ transplantation, wound and cardiac surgical procedure in or the blood of postoperative generation
Bolt disease.
At present, existing thrombelastogram instrument is many based on two Air conduct measurement, minority four-way
Instrument also simply adds passage simply, it is impossible to accomplishing that passage extends flexibly, other functions do not have
Big improvement, the detection cycle is the longest, operates the most loaded down with trivial details, and labor intensity is very big, to behaviour
The proficiency level of author requires higher, has extremely been unfavorable for a large amount of Detection task.It addition, not
The compatibility of same type machine is poor, it is impossible to accomplish that multi-model interconnects, and between the most each instrument, circuit is numerous
Miscellaneous, it is impossible to accomplishing wireless interconnected, use is inconvenient for.Further, the existing many installations of instrument accessory
Loaded down with trivial details, intelligent the highest with integrated level, it is unfavorable for using.
Summary of the invention
(1) to solve the technical problem that
It is an object of the invention to provide a kind of multichannel thrombelastogram instrument, it can be according to reality
Need to carry out flexibly passage extension, and the detection cycle can be shortened, simplify operating process, carry
The intellectuality of high instrument and integrated level, can accomplish multi-model interconnection, wireless interconnected simultaneously.
(2) technical scheme
In order to solve above-mentioned technical problem, the present invention provides a kind of multichannel thrombelastogram instrument,
It include data and signal processing module and with described data and signal processing module interconnection
Data acquisition module, temperature control modules, motion-control module, level module and communication module,
Described data acquisition module connects multiple measurement module, and the connection of described temperature control modules has pre-
Thermal modules and multiple heating module, described motion-control module connects loading module, unloading mould
Block, test module, turn module and reseting module；
Described measurement module is for measuring and obtain micro-in whole coagulation process of blood sample in real time
Little variable quantity, and it is converted into the digital signal of convenient process；
Described data acquisition module exports for the one or more described measurement module of Real-time Collection
Digital signal, and data are made pretreatment；
Described warm-up block is used for assisting to preheat blood sample, when accelerating the early-stage preparations of blood sample test
Between；
Described heating module is for maintaining blood sample to be in a default steady temperature；
Described temperature control modules is used for controlling described warm-up block and one or more described
The real time temperature of heating module, can regulate heating parameters in real time according to different heating state, it is achieved
Optimal control；
Described loading module is for being automatically installed to the test cup holding blood sample with test bowl cover
Desired position, ready for blood sample test；
Described Unload module is for automatically unloading described test cup from installation site with test bowl cover
Carry；
Described test module is for automatically starting the test job of blood sample to be measured；
Described turn module is used for maintaining described test cup and test cup to be stamped a fixed angle
Reciprocal turn action, assist blood sample test job；
Described reseting module is for realizing homing action or the back to zero action of system；
Described motion-control module be used for controlling described loading module, Unload module, test module,
Turn module and the athletic performance of reseting module；
Described level module is used for gathering in real time the level of described multichannel thrombelastogram instrument
State, and it is converted into the digital signal of convenient process, automatically control the horizontal of this elastic force figure instrument
State；
Described data and signal processing module are for receiving and processing from described data acquisition module
The various information of block, temperature control modules, motion-control module and level module；
Described communication module has been used for the communication need of described data and signal processing module, real
Existing information is mutual；
Described communication module is also associated with passage expansion module, for leading to the most flexibly
Road extends.
Described multichannel thrombelastogram instrument also includes host computer, described host computer and described communication
Module connects, for the process information of the described data of display in real time with signal processing module.
Described multichannel thrombelastogram instrument also includes external interface module, described external interface mould
Block is connected with described communication module, is used for connecting external equipment.
Described external interface module can be PS/2 interface, RS-232, RS-485, LPT, lead to
By the one in network interface, USB2.0 interface, USB3.0 interface and VGA output interface or
Multiple.
Described external interface module is connected with external equipment by wireless network.
Preferably, described multichannel thrombelastogram instrument includes four TCH test channels, each described
TCH test channel includes independent described measurement module, heating module, loading module, unloading respectively
Module, test module, turn module and reseting module.
The present invention also provides for the user of a kind of multichannel thrombelastogram instrument as described above
Method, comprises the steps:
First start this multichannel thrombelastogram instrument, after its power-on self-test, wait behaviour
Making, wherein said level module controls the level of this instrument；
S2. select suitable TCH test channel according to the blood examination of patient, start test assignment,
Wherein said temperature control modules controls described heating module and keeps preset temperature with warm-up block,
Loading module, Unload module, test module, turn mould described in described moving control module for controlling
Block and the on-demand action of reseting module；
The most described data acquisition module obtains the digital signal of described measurement module output, carries out
Data prediction；
The most described data receive from described data acquisition module, temperature with signal processing module
Data that control module, motion-control module and level module are corresponding, temperature, operating state,
Level status information, and carry out integrated treatment one by one；
The most described communication module completes each of described data and signal processing module and host computer
Plant communication, it is achieved the data described in S4, temperature, operating state, level status information are handed over
Mutually；
The most described host computer and described communication module interconnect, complete data analysis, result shows,
Data storage, report print, touch screen controls, wizard-like operates, state shows, parameter is arranged
And Multichannel fusion；
S7. complete test assignment, realize action by described reseting module and automatically reset, finally
Close instrument.
(3) beneficial effect
Compared with prior art, the invention have the advantages that
A kind of multichannel thrombelastogram instrument of present invention offer and using method, described multichannel
Thrombelastogram instrument uses data acquisition module, level module, temperature control modules, motion control
Molding block and communication module interconnect with signal processing module with described data, it is possible to monitoring in real time should
Data, level, temperature and the operating state that instrument is corresponding, described communication module connects
Having passage expansion module, it can carry out Multi-channel extension, Multichannel fusion, described number neatly
Being simultaneously connected with multiple measurement module according to acquisition module, described temperature control modules connects preheating
Module and multiple heating module, described motion-control module connect have loading module, Unload module,
Test module, turn module and reseting module, it is possible to realize automatic intelligent control, it is achieved many
Plant quick input, simple to operation, and stability is strong, good in anti-interference performance, and can be all sidedly
The blood coagulation overall picture of detection patient, can quickly determine therapeutic scheme, has been conducive to detecting in a large number and has appointed
Business, saves treatment time, wins life.
Accompanying drawing explanation
Fig. 1 is the connection block diagram of the present invention a kind of multichannel thrombelastogram instrument.
Detailed description of the invention
Below in conjunction with the accompanying drawings and embodiment, the detailed description of the invention of the present invention is made the most in detail
Describe.Following instance is used for illustrating the present invention, but is not limited to the scope of the present invention.
In describing the invention, it should be noted that term " first ", " second ", "
Three " etc. it is only used for describing purpose, and it is not intended that instruction or hint relative importance.
In describing the invention, it should be noted that unless otherwise clearly defined and limited,
Term " is installed ", " being connected ", " connection " should be interpreted broadly, for example, it may be fixing even
Connect, it is also possible to be to removably connect, or be integrally connected；Can be to be mechanically connected, it is also possible to
It it is electrical connection；Can be to be joined directly together, it is also possible to be indirectly connected to by intermediary, Ke Yishi
The connection of two element internals.For the ordinary skill in the art, can concrete feelings
Condition understands above-mentioned term concrete meaning in the present invention.
Additionally, in describing the invention, except as otherwise noted, " multiple ", " many ", " many
Group " it is meant that two or more.
As it is shown in figure 1, a kind of multichannel thrombelastogram instrument provided for the present invention, it includes
Data and signal processing module and the data acquisition with described data with signal processing module interconnection
Collection module, temperature control modules, motion-control module, level module and communication module, described
Data acquisition module connects has multiple measurement module, described measurement module to be preferably four, by four
Consistent but the separate measurement module of individual function collectively constitutes, the respectively first measurement module,
Second measurement module, the 3rd measurement module and the 4th measurement module；Described temperature control modules is even
Being connected to warm-up block and multiple heating module, described heating module is preferably four, by four merits
Heating module that can be consistent but separate forms, the respectively first heating module, the second heating
Module, the 3rd heating module and the 4th heating module；Described motion-control module connects dress
Carry module, Unload module, test module, turn module and reseting module；One standard is many
Passage thrombelastogram instrument comprises four TCH test channels (TCH test channel can extend), wherein,
Each TCH test channel has independent measurement module, heating module, loading module, unloads mould
Block, tests module, turn module and reseting module；Each TCH test channel both can independent work
Make, it is also possible to other TCH test channels collaborative work together.
Described measurement module is used for measuring in real time and accurately acquiring blood sample at whole coagulation process
In change, and be converted into the digital signal of convenient process；
Described data acquisition module exports for the one or more described measurement module of Real-time Collection
Digital signal, and data are made pretreatment；
Described warm-up block is used for assisting to preheat blood sample, accelerates the early-stage preparations of blood sample test job
Time；
Described heating module for accurately maintain blood sample or reagent be in one default constant
Temperature；
Described temperature control modules is used for controlling described warm-up block and one or more described
The real time temperature of heating module, can regulate heating parameters in real time according to different heating state, it is achieved
Optimal control；
Described loading module is for being automatically installed to the test cup holding blood sample with test bowl cover
Desired position, ready for blood sample test；
Described Unload module is for automatically unloading described test cup from installation site with test bowl cover
Carry；
Described test module is for automatically starting the test job of blood sample to be measured；
Described turn module is used for maintaining described test cup and test cup to be stamped a fixed angle
Reciprocal turn action, assist blood sample test job；
Described reseting module is for realizing homing action or the back to zero action of system；
Described motion-control module and described loading module, Unload module, test module, turn
Module and reseting module interconnection, for steadily efficiently controlling described loading module, unloading mould
Block, test module, turn module and the athletic performance of reseting module, it both can independently be controlled
Individual module processed, it is also possible to the multiple module of coordinated signals；
Described level module is for gathering described multichannel thrombelastogram instrument precisely in real time
Level, and it is converted into the digital signal of convenient process, automatically control this thrombelastogram instrument
Level；
Described data and signal processing module and described data acquisition module, temperature control modules,
Motion-control module and level module interconnection, for receiving and processing from described data acquisition
Data that module, temperature control modules, motion-control module and level module are corresponding, temperature,
The much information such as operating state, level；
Described communication module interconnects with host computer, has been used for described data and signal processing module
Various communication needs with host computer, it is achieved data, temperature, operating state, level etc.
Information is mutual, and realizes data analysis by described host computer, and result shows, data store,
Report prints, and touch screen controls, and state shows, parameter is arranged, Multichannel fusion, and wizard-like is grasped
Make；
Described communication module is also associated with passage expansion module, can realize more multichannel extension merit
Can, for carrying out passage extension the most flexibly, it is possible to realizing multimachine interconnection, multi-model is mutual
Connection and strange land interconnecting function.
Described multichannel thrombelastogram instrument also includes external interface module, described external interface mould
Block is connected with described communication module, is used for connecting external equipment, for example, it is possible to connect printer,
Realize report printout, connecting bar code reader, scan for one-dimension code and Quick Response Code, even
Connect keyboard and mouse etc..
Described external interface module can be PS/2 interface, RS-232, RS-485, LPT(Line
Print Terminal, printing terminal), universal network interface, USB2.0 interface, USB3.0 connect
Mouthful and VGA(Video Graphics Array, Video Graphics Array) one in output interface
Or multiple, described external interface module can be by infrared, bluetooth, WLAN(Wireless Local
Area Networks, WLAN) or the wireless network such as 3G be connected with external equipment.
Present invention also offers and a kind of utilize making of multichannel thrombelastogram instrument described above
By method, concretely comprise the following steps:
First start this multichannel thrombelastogram instrument, after its power-on self-test, wait behaviour
Making, wherein said level module controls the level of this instrument；
S2. select suitable TCH test channel according to the blood examination of patient, start test assignment,
Wherein said temperature control modules controls described heating module and keeps preset temperature with warm-up block,
Loading module, Unload module, test module, turn mould described in described moving control module for controlling
Block and the on-demand action of reseting module；
The most described data acquisition module obtains the digital signal of described measurement module output, carries out
Data prediction；
The most described data and signal processing module receive the most in an orderly manner from described data acquisition
Collect data corresponding to module, temperature control modules, motion-control module and level module, temperature
The information such as degree, operating state, level, and carry out integrated treatment one by one；
The most described communication module completes each of described data and signal processing module and host computer
Plant communication, it is achieved the information such as the data described in S4, temperature, operating state, level
Alternately；
The most described host computer and described communication module interconnect, complete data analysis, result shows,
Data storage, report print, touch screen controls, wizard-like operates, state shows, parameter is arranged,
The tasks such as Multichannel fusion；
S7. complete test assignment, realize action by described reseting module and automatically reset, finally
Close instrument.
The present invention can carry out Multi-channel extension, Multichannel fusion neatly, and automatic intelligent controls,
Touch screen interface, wizard-like operates, and big data store, intelligence report, multiple quick input, letter
Single easily operation；Good in anti-interference performance, can detect the blood coagulation overall picture of patient all sidedly, can be the most true
Determine therapeutic scheme, be conducive to a large amount of Detection task, save treatment time, win life；
Support different type of machines interconnection, multi-model interconnection, support multiple standards interface, support wireless telecommunications,
Easy to use.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention,
All within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made,
Should be included within the scope of the present invention.
Claims (7)
1. a multichannel thrombelastogram instrument, it is characterised in that include data and signal processing
Module and data acquisition module, temperature with described data with signal processing module interconnection control
Module, motion-control module, level module and communication module, described data acquisition module connects
Having multiple measurement module, described temperature control modules connects warm-up block and multiple heated mould
Block, described motion-control module connects loading module, Unload module, test module, turn
Module and reseting module；
Described measurement module is for measuring and obtain micro-in whole coagulation process of blood sample in real time
Little variable quantity, and it is converted into the digital signal of convenient process；
Described data acquisition module exports for the one or more described measurement module of Real-time Collection
Digital signal, and data are made pretreatment；
Described warm-up block is used for assisting to preheat blood sample, when accelerating the early-stage preparations of blood sample test
Between；
Described heating module is for maintaining blood sample to be in a default steady temperature；
Described temperature control modules is used for controlling described warm-up block and one or more described
The real time temperature of heating module, can regulate heating parameters in real time according to different heating state；
Described loading module is for being automatically installed to the test cup holding blood sample with test bowl cover
Desired position, ready for blood sample test；
Described Unload module is for automatically unloading described test cup from installation site with test bowl cover
Carry；
Described test module is for automatically starting the test job of blood sample to be measured；
Described turn module is used for maintaining described test cup and test cup to be stamped a fixed angle
Reciprocal turn action, assist blood sample test job；
Described reseting module is for realizing homing action or the back to zero action of system；
Described motion-control module be used for controlling described loading module, Unload module, test module,
Turn module and the athletic performance of reseting module；
Described level module is used for gathering in real time the level of described multichannel thrombelastogram instrument
State, and it is converted into the digital signal of convenient process, automatically control the horizontal of this elastic force figure instrument
State；
Described data and signal processing module are for receiving and processing from described data acquisition module
The various information of block, temperature control modules, motion-control module and level module；
Described communication module has been used for the communication need of described data and signal processing module, real
Existing information is mutual；
Described communication module is also associated with passage expansion module, for leading to the most flexibly
Road extends.
2. multichannel thrombelastogram instrument as claimed in claim 1, it is characterised in that also wrap
Including host computer, described host computer is connected with described communication module, shows described data in real time
Process information with signal processing module.
3. multichannel thrombelastogram instrument as claimed in claim 1, it is characterised in that also wrap
Including external interface module, described external interface module is connected with described communication module, is used for connecting
External equipment.
4. multichannel thrombelastogram instrument as claimed in claim 3, it is characterised in that described
External interface module be PS/2 interface, RS-232, RS-485, LPT, universal network interface,
One or more in USB2.0 interface, USB3.0 interface and VGA output interface.
5. multichannel thrombelastogram instrument as claimed in claim 4, it is characterised in that described
External interface module is connected with external equipment by wireless network.
6. multichannel thrombelastogram instrument as claimed in claim 1, it is characterised in that its bag
Include four TCH test channels, each described TCH test channel include respectively independent described measurement module,
Heating module, loading module, Unload module, test module, turn module and reseting module.
7. the use of the multichannel thrombelastogram instrument as described in any one of claim 1-6
Method, it is characterised in that comprise the steps:
First start this multichannel thrombelastogram instrument, after its power-on self-test, wait behaviour
Making, wherein said level module controls the level of this instrument；
S2. select suitable TCH test channel according to the blood examination of patient, start test assignment,
Wherein said temperature control modules controls described heating module and keeps preset temperature with warm-up block,
Loading module, Unload module, test module, turn mould described in described moving control module for controlling
Block and the on-demand action of reseting module；
The most described data acquisition module obtains the digital signal of described measurement module output, carries out
Data prediction；
The most described data receive from described data acquisition module, temperature with signal processing module
Data that control module, motion-control module and level module are corresponding, temperature, operating state,
Level status information, and carry out integrated treatment one by one；
The most described communication module completes each of described data and signal processing module and host computer
Plant communication, it is achieved the data described in S4, temperature, operating state, level status information are handed over
Mutually；
The most described host computer and described communication module interconnect, complete data analysis, result shows,
Data storage, report print, touch screen controls, wizard-like operates, state shows, parameter is arranged
And Multichannel fusion；
S7. complete test assignment, realize action by described reseting module and automatically reset, finally
Close instrument.
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| CN201410155035.2A CN105004868B (en) | 2014-04-17 | 2014-04-17 | A kind of multichannel thrombelastogram instrument and using method |
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| CN106405063B (en) * | 2016-08-30 | 2019-06-04 | 诺泰科生物科技（苏州）有限公司 | A kind of thrombus elastometer and contain blood cup cup lid handling method |
| CN109142698A (en) * | 2018-07-27 | 2019-01-04 | 深圳优迪生物技术有限公司 | Solution elasticity testing device |
| CN109470879A (en) * | 2018-10-22 | 2019-03-15 | 北京乐普智慧医疗科技有限公司 | A kind of Portable type full-automatic micro-current control biochemical analyzer |
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| US6225126B1 (en) * | 1999-02-22 | 2001-05-01 | Haemoscope Corporation | Method and apparatus for measuring hemostasis |
| US6890299B2 (en) * | 2003-04-08 | 2005-05-10 | Haemoscope Corporation | Method and apparatus for monitoring hemostasis in connection with artificial surface devices |
| US8070678B2 (en) * | 2005-10-05 | 2011-12-06 | Gurbel Paul A | Detection of restenosis risk in patients receiving a stent by measuring the characteristics of blood clotting including the measurement of maximum thrombin-induced clot strength |
| WO2009075891A2 (en) * | 2007-12-12 | 2009-06-18 | Kmg2 Sensors Corporation (Kmg2) | Magnetoelastic sensor element having a liquid-solid interface with a roughened nano/microstructure |
| CN203203995U (en) * | 2013-04-19 | 2013-09-18 | 陕西裕泽毅医疗科技有限公司 | Multi-channel thrombus elasticity detector |
| CN103398922B (en) * | 2013-07-09 | 2015-09-30 | 广东石油化工学院 | A kind of thrombus elastic force measuring device and measuring method thereof |
| CN203616327U (en) * | 2013-12-06 | 2014-05-28 | 北京中勤世帝生物技术有限公司 | Measuring device for thrombus elasticity |
| CN203825015U (en) * | 2014-04-17 | 2014-09-10 | 北京乐普医疗科技有限责任公司 | Multi-channel thrombelastogram instrument |
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