CN104997955A

CN104997955A - External drug for improving myopia and its preparation method and use

Info

Publication number: CN104997955A
Application number: CN201510405073.3A
Authority: CN
Inventors: 韩红卫
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-07-09
Filing date: 2015-07-09
Publication date: 2015-10-28

Abstract

The invention discloses an external drug for improving myopia and its preparation method and use. The external drug is prepared from 4-12 parts by weight of cornu saigae tataricae, 1-5 parts by weight of bear gall, 5-10 parts by weight of dry sclerotia of Poria cocos(Schw.)Wolf, 5-10 parts by weight of calculus bovis, 7-15 parts by weight of saffron crocus, 1-5 parts by weight of armadillo scale, 10-15 parts by weight of radix astragali, 1-5 parts by weight of periostracum cicadae, 5-15 parts by weight of motherwort, 1-5 parts by weight of spirifer, 1-5 parts by weight of pearl shell, 1-5 parts by weight of Chinese angelica, 1-5 parts by weight of pilose asiabell root, 1-5 parts by weight of fructus rosae laevigatae, 10-20 parts by weight of sesame stalk and 10-20 parts by weight of bean root. The invention discloses a preparation method and use of the external drug. Through cooperation of the components, the external drug has effects of clearing liver and improving eyesight, removing eye opacity, stimulating circulation of the blood, and invigorating blood circulation and tonifying qi, and can improve or treat myopia.

Description

For improving near-sighted external used medicine, its preparation method and application thereof

Technical field

The present invention relates to the medicine being used for the treatment of myopia, the invention still further relates to preparation method and the application thereof of this medicine.

Background technology

Along with the accelerated development of modern electronic product, the people of myopia gets more and more, especially teenager.At present, the method for the treatment of myopia mainly contains: (1) is equipped with rational glasses for the myopia: (2) use near-sighted instrument, controls myopia progression; (3) operative treatment, as laser etc.; (4) Drug therapy.

Application number be 201110310008.4 Chinese invention patent application disclose one and treat near-sighted medicine, be made up of following component (weight portion): Laggera alata (Roxb.) Sch.-Bip. 15 ~ 30, Caulis et folium vitis thunbergii 30 ~ 60, Hu Tui 25 ~ 50, boxthorn root 25 ~ 50, Spora Lygodii 15 ~ 30, the Radix Astragali 10 ~ 20, Flos Eriocauli 10 ~ 20, Semen Plantaginis 10 ~ 20, Concha Haliotidis 40 ~ 60.The usage and dosage of this medicine is: every day three times, divides early, middle and late taking, need take 50 days.This medicine is oral medicine, and the cycle of taking is longer, can produce certain harm to human body (especially teenager).

Summary of the invention

The object of the present invention is to provide the external used medicine for improving or treat myopia that a kind of, life cycle less to harm is shorter, with at least one aspect in solving the problems of the technologies described above.

Another object of the present invention is the preparation method providing a kind of above-mentioned external used medicine, with at least one aspect in solving the problems of the technologies described above.

Another object of the present invention is the application providing a kind of above-mentioned external used medicine, with at least one aspect in solving the problems of the technologies described above.

According to an aspect of the present invention; the invention provides a kind of external used medicine for improving myopia, its effective ingredient is made up of the crude drug of following weight portion: Cornu Saigae Tataricae 4 ~ 12 parts, Fel Ursi 1 ~ 5 part, BAIFU god 5 ~ 10 parts, Calculus Bovis 5 ~ 10 parts, Stigma Croci 7 ~ 15 parts, armadillo scale 1 ~ 5 part, the Radix Astragali 10 ~ 15 parts, Periostracum Cicadae 1 ~ 5 part, Herba Leonuri 5 ~ 15 parts, 1 ~ 5 part, Fossilia Spiriferis, Concha Margaritifera 1 ~ 5 part, Radix Angelicae Sinensis 1 ~ 5 part, Radix Codonopsis 1 ~ 5 part, Fructus Rosae Laevigatae 1 ~ 5 part, Caulis Sesami 10 ~ 20 parts and Radix Sophorae Tonkinensis 10 ~ 20 parts.

In the embodiment that some are concrete, the effective ingredient of said medicine can be preferably made up of the crude drug of following weight portion: Cornu Saigae Tataricae 4 ~ 8 parts, Fel Ursi 2 ~ 3 parts, BAIFU god 5 ~ 8 parts, Calculus Bovis 5 ~ 7 parts, Stigma Croci 7 ~ 10 parts, armadillo scale 1 ~ 3 part, the Radix Astragali 10 ~ 15 parts, Periostracum Cicadae 1 ~ 3 part, Herba Leonuri 5 ~ 10 parts, 1 ~ 3 part, Fossilia Spiriferis, Concha Margaritifera 1 ~ 3 part, Radix Angelicae Sinensis 1 ~ 3 part, Radix Codonopsis 1 ~ 3 part, Fructus Rosae Laevigatae 1 ~ 3 part, Caulis Sesami 10 ~ 15 parts and Radix Sophorae Tonkinensis 10 ~ 15 parts.

In the embodiment that some are concrete, the effective ingredient of said medicine can be more preferably made up of the crude drug of following weight portion: Cornu Saigae Tataricae 6 parts, Fel Ursi 3 parts, BAIFU god 7 parts, Calculus Bovis 6 parts, Stigma Croci 10 parts, armadillo scale 3 parts, the Radix Astragali 15 parts, Periostracum Cicadae 3 parts, Herba Leonuri 10 parts, 3 parts, Fossilia Spiriferis, Concha Margaritifera 3 parts, Radix Angelicae Sinensis 3 parts, Radix Codonopsis 3 parts, Fructus Rosae Laevigatae 3 parts, Caulis Sesami 12 parts and Radix Sophorae Tonkinensis 10 parts.

In the embodiment that some are concrete, said medicine can also comprise pharmaceutically acceptable carrier.

In the embodiment that some are concrete, said medicine can be patch or unguentum.

In the present invention, Cornu Saigae Tataricae has the effect of suppressing the hyperactive liver to relieve the wind syndrome, removing pathogenic heat from blood and toxic substance from the body; Fel Ursi has the effect of heat-clearing and toxic substances removing, suppressing the hyperactive liver improving eyesight; Calculus Bovis has the effect of heat-clearing and toxic substances removing; Periostracum Cicadae has the effect of dispelling wind-heat, removing nebula to improve visual acuity; Fossilia Spiriferis is except damp and hot, to move back corneal nebula effect; Concha Margaritifera has effect of liver heat removing and eyesight improving; Radix Sophorae Tonkinensis has effect of eliminating fire and detoxication.And BAIFU god has mind calming, calms the nerves, controls the functions such as palpitation with fear of having a guilty conscience; The Radix Astragali has the effect that QI invigorating protects the liver; Stigma Croci has very strong blood circulation promoting and blood stasis dispelling and effect of dispersing stagnation and relieving accumulation of pathogens; The effects such as armadillo scale has invigorating blood circulation, subsides a swelling, evacuation of pus; Herba Leonuri has the effect of blood circulation promoting and blood stasis dispelling; Radix Angelicae Sinensis has the effect of blood circulation promoting and enriching; Radix Codonopsis can invigorating the spleen and replenishing QI; Fructus Rosae Laevigatae has the effect of QI invigorating; Caulis Sesami has the effect of QI invigorating.Whole pharmaceutical formulation, cooperatively interacts between each component, row liver heat removing and eyesight improving, moves back the effect of corneal nebula, soothing the channels and quicking the network vessels, polishing of invigorating blood circulation.

According to a further aspect in the invention, present invention also offers the preparation method of the above-mentioned external used medicine for improving myopia, comprising the following steps:

(1) BAIFU god, the Radix Astragali, Herba Leonuri, Fructus Rosae Laevigatae, Caulis Sesami and Radix Sophorae Tonkinensis is got in proportion, add water 1000 ~ 2000 parts, 2 ~ 4 hours are decocted at 80 ~ 90 DEG C, add Concha Margaritifera and Periostracum Cicadae in proportion, at 80 ~ 90 DEG C, decoct 2 ~ 4 hours, add Stigma Croci in proportion, 2 ~ 4 hours are decocted at 80 ~ 90 DEG C, from fiery natural cooling, filter and remove residue, medicinal liquid slow fire infusion 2 ~ 4 hours;

(2) Cornu Saigae Tataricae, Fel Ursi, Calculus Bovis, armadillo scale, Fossilia Spiriferis, Radix Angelicae Sinensis and Radix Codonopsis is got in proportion; mixing after pulverizing; add edible ethanol 1000 ~ 2000 parts, at 70 ~ 80 DEG C, decoct 6 ~ 12 hours, get 2 ~ 5, ripe egg; abandon and whitely get Huang; be placed in medicinal liquid to use moderate heat instead and decoct to shrivelled browning color, use intense fire instead and urge oil, press egg yolk with dipper simultaneously; collecting oozes brown egg oil, is mixed by the medicinal liquid of egg oil with step (1) gained.

In the embodiment that some are concrete, above-mentioned preparation method can also comprise the following steps: add pharmaceutically acceptable carrier, is made into patch, oil preparation or unguentum.

Preparation method of the present invention, technique is simple, and is fully extracted the effective ingredient of each component, and facilitate post-production to become patch, oil preparation or unguentum, patient's routine use is very convenient.

According to a further aspect in the invention, present invention also offers the application of above-mentioned external used medicine in improvement, treatment myopia.

According to another aspect of the invention, present invention also offers a kind of method improving myopia, comprise the following steps:

(1) utilize pat, magnetic force meridians beat or photon energy dredging eye surrounding, thoracic vertebra, cervical vertebra meridians, promote blood and the lymph circulation of eye surrounding, strengthen chest and the vertebrarterial blood supply ability of neck;

(2) by drug effect of the present invention in particular acupoint 12 ~ 24 hours, with by the silting in Liver Channel, urinary bladder channel, spleen channel cleaning human body, described particular acupoint refer in Jingming acupoint, Yintang acupoint, SIBAI point, Tongziliao acupoint, yang white cave, the bright cave of nebula, outer photohole, point Hegu and TAICHONG acupoint one or more;

(3) temper eye muscle every day 1 ~ 5 time, described exercise eye muscle is:

Keep head motionless forward at indoor or outdoors, eyes are done 360 degree of positive and negative movements and are looked around, and practise 1 ~ 3 minute at every turn;

Or motionless forward at outdoor maintenance head, look far into the distance, eyes make 180 degree of horizontal bidirectional movable hypermetropias, till can not rotating, practise 1 ~ 3 minute at every turn;

Or, stretch out a forefinger among two, move at a slow speed from as far as early work, two eye fixation forefingers, till there is diplopia, practise 0.5 ~ 3 minute at every turn;

Or closed 4 ~ 6 seconds of first eyes, then, moment of opening eyes closes eyes 4 ~ 6 seconds again, so circulates, practises 0.5 ~ 3 minute.

The method improving myopia of the present invention, first dredging the meridian, then by drug effect in specific acupuncture point, drug effect is put in place rapidly, and plays its effect, in short-term (about 4 weeks), just can improve vision, again in conjunction with self training to eye, can ensure that vision restoration does not rebound.

Detailed description of the invention

Below by embodiment, the present invention is further detailed explanation.

(1) BAIFU god, the Radix Astragali, Herba Leonuri, Fructus Rosae Laevigatae, Caulis Sesami and Radix Sophorae Tonkinensis is got in the ratio in table 1, add water in the ratio in table 1,2 ~ 4 hours are decocted at 80 ~ 90 DEG C, add Concha Margaritifera and Periostracum Cicadae in proportion, at 80 ~ 90 DEG C, decoct 2 ~ 4 hours, add Stigma Croci in proportion, 2 ~ 4 hours are decocted at 80 ~ 90 DEG C, from fiery natural cooling, filter and remove residue, medicinal liquid slow fire infusion 2 ~ 4 hours;

(2) Cornu Saigae Tataricae, Fel Ursi, Calculus Bovis, armadillo scale, Fossilia Spiriferis, Radix Angelicae Sinensis and Radix Codonopsis is got in the ratio in table 1; mixing after pulverizing; edible ethanol is added in the ratio in table 1; 6 ~ 12 hours are decocted at 70 ~ 80 DEG C; get ripe egg; abandon and whitely get Huang; be placed in medicinal liquid to use moderate heat instead and decoct to shrivelled browning color; use intense fire instead and urge oil; press egg yolk with dipper simultaneously; collecting oozes brown egg oil, is mixed by the medicinal liquid of egg oil with step (1) gained, namely obtains the external used medicine for improving myopia of the present invention.

(3) in addition, pharmaceutically acceptable carrier can also be added, be made into patch, oil preparation or unguentum.

	Embodiment 1	Embodiment 2	Embodiment 3	Embodiment 4	Embodiment 5	Embodiment 6	Embodiment 7
								BAIFU god	5	6	7	8	9	10	7

The Radix Astragali	14	15	10	11	12	13	15
								Herba Leonuri	15	14	12	10	8	5	10
Fructus Rosae Laevigatae	5	4	3	2	1	3	3
								Caulis Sesami	20	10	12	14	16	18	12
Radix Sophorae Tonkinensis	16	20	10	14	18	12	10
								Concha Margaritifera	2	1	4	3	5	4	3
Periostracum Cicadae	3	4	3	1	2	5	3
								Stigma Croci	7	14	9	10	12	15	10
Water	1000	1500	2000	1800	1300	1600	1700
								Cornu Saigae Tataricae	4	6	8	10	12	8	6
Fel Ursi	3	5	4	3	1	2	3
								Calculus Bovis	6	10	9	8	5	7	6
Armadillo scale	1	2	3	4	5	3	3
								Fossilia Spiriferis	3	5	1	2	3	4	3
Radix Angelicae Sinensis	4	3	2	2	1	5	3
								Radix Codonopsis	2	1	3	4	2	5	3
Ethanol	1500	1000	2000	1200	1600	1800	1400
								Egg	2	3	4	5	3	4	5

Table 1

In order to verify the effect of medicine of the present invention, following test is carried out to above-mentioned obtained medicine:

(1) man of all ages and classes, female myope totally 7 is chosen.

(2) utilize pat, magnetic force meridians beat or photon energy dredging eye surrounding, thoracic vertebra, cervical vertebra meridians, promote blood and the lymph circulation of eye surrounding, strengthen chest and the vertebrarterial blood supply ability of neck.

Dredging collateral mends magnetic, get through meridians by modern high technology photon energy instrument, utilize high magnetic energy to fill used meridians, acupuncture point, affect the magnetic moment orientation of body current distribution and biopolymer, the physiology of ocular tissue's cell, biochemical process are changed, generation current in vivo, the elasticity increasing blood vessel wall distends the blood vessels, and promotes blood and lymph circulation near the eyes, accelerate blood flow, eliminate thromboembolism, final dredging the meridian silting, increase hematological activity.Only have that air flue is logical, blood road logical, anus is logical, water channel is logical, meridians lead to naturally, the QI and blood of eyes is in liberal supply is the prerequisite of true myopia rehabilitation.

Thoracic vertebra, cervical vertebra are head QI and blood passages, and chest and cervical vertebra cerebral arterial insufficiency make cerebral cortex visual projection maincenter flow lower, then cause the visual deterioration of central.Corrected cervical vertebra, thoracic vertebra and be accustomed to the little dislocation that causes because of bad eye, making thoracic vertebra, cervical vertebra QI and blood unobstructed is the key solving amblyopia rehabilitation.

(2) by above-mentioned obtained drug effect in particular acupoint 12 ~ 24 hours, with by the silting in Liver Channel, urinary bladder channel, spleen channel cleaning human body, described particular acupoint refer in Jingming acupoint, Yintang acupoint, SIBAI point, Tongziliao acupoint, yang white cave, the bright cave of nebula, outer photohole, point Hegu and TAICHONG acupoint one or more.

" blood circulation promoting and blood stasis dispelling-strengthening vital QI to eliminate pathogenic factors " local treatment is used according to near-sighted pathogeny, multiple natural famous and precious rare plant is adopted to skim the cream off milk, adopt biological micromolecule cutting technique, by pure biological prescription micromolecule, effect is released in particular acupoint 12 ~ 24 hours perseverances, thus follow in extremely, tonify deficiency righting, inner disease outer treat.The elite of famous and precious rare plant, through Fast Persistence cleaning siltings such as liver network, urinary bladder channel, spleen channels, dissolves silting, supplements the nutrients.Allow the healthy blood nourishing eyes muscle again of cleaned mistake, thus allow ciliary muscle, extraocular muscles etc. complete self-regeneration, fundamentally recover the regulating action to eyes.So fundamentally organ inner-outer circulation balance in upper solution eyeball, crystalline lens varieties of intraocular pressure is normal, thus allows eyeball naturally reset, and axis oculi recovers normal, near-sighted amblyopia rehabilitation.

(3) method in table 2 is adopted every day to temper eye muscle 1 ~ 5 time.

" YIN and YANG in a relative equilibrium, life activities being normally maintained " physical therapy myopia needs exciting human yang-energy, mainly by training.By training, with breathless interest, can QI and blood regulating, depressed liver-energy dispersing and QI regulating, tempers the eye muscle such as ciliary muscle, thus reaches the object that interior tune dispatches workers to do on-site repairs, and allows the strong that ciliary muscle recovers.

(4) step (1) ~ (3) are repeated weekly once, by logging to table 2 after 4 weeks.

Table 2

As shown in Table 2, medicine of the present invention, has significant effect to improving vision, and drug effect is rapid, just plays the effect improving vision in a short time, then in conjunction with self training to eye, can ensure that vision restoration does not rebound.

Above-described is only some embodiments of the present invention.For the person of ordinary skill of the art, without departing from the concept of the premise of the invention, can also make some distortion and improvement, these all belong to protection scope of the present invention.

Claims

1. for improving the external used medicine of myopia; it is characterized in that, its effective ingredient is made up of the crude drug of following weight portion: Cornu Saigae Tataricae 4 ~ 12 parts, Fel Ursi 1 ~ 5 part, BAIFU god 5 ~ 10 parts, Calculus Bovis 5 ~ 10 parts, Stigma Croci 7 ~ 15 parts, armadillo scale 1 ~ 5 part, the Radix Astragali 10 ~ 15 parts, Periostracum Cicadae 1 ~ 5 part, Herba Leonuri 5 ~ 15 parts, 1 ~ 5 part, Fossilia Spiriferis, Concha Margaritifera 1 ~ 5 part, Radix Angelicae Sinensis 1 ~ 5 part, Radix Codonopsis 1 ~ 5 part, Fructus Rosae Laevigatae 1 ~ 5 part, Caulis Sesami 10 ~ 20 parts and Radix Sophorae Tonkinensis 10 ~ 20 parts.

2. the external used medicine for improving myopia according to claim 1; it is characterized in that, its effective ingredient is made up of the crude drug of following weight portion: Cornu Saigae Tataricae 4 ~ 8 parts, Fel Ursi 2 ~ 3 parts, BAIFU god 5 ~ 8 parts, Calculus Bovis 5 ~ 7 parts, Stigma Croci 7 ~ 10 parts, armadillo scale 1 ~ 3 part, the Radix Astragali 10 ~ 15 parts, Periostracum Cicadae 1 ~ 3 part, Herba Leonuri 5 ~ 10 parts, 1 ~ 3 part, Fossilia Spiriferis, Concha Margaritifera 1 ~ 3 part, Radix Angelicae Sinensis 1 ~ 3 part, Radix Codonopsis 1 ~ 3 part, Fructus Rosae Laevigatae 1 ~ 3 part, Caulis Sesami 10 ~ 15 parts and Radix Sophorae Tonkinensis 10 ~ 15 parts.

3. the medicine external thing for improving myopia according to claim 1; it is characterized in that, its effective ingredient is made up of the crude drug of following weight portion: Cornu Saigae Tataricae 6 parts, Fel Ursi 3 parts, BAIFU god 7 parts, Calculus Bovis 6 parts, Stigma Croci 10 parts, armadillo scale 3 parts, the Radix Astragali 15 parts, Periostracum Cicadae 3 parts, Herba Leonuri 10 parts, 3 parts, Fossilia Spiriferis, Concha Margaritifera 3 parts, Radix Angelicae Sinensis 3 parts, Radix Codonopsis 3 parts, Fructus Rosae Laevigatae 3 parts, Caulis Sesami 12 parts and Radix Sophorae Tonkinensis 10 parts.

4. the external used medicine for improving myopia according to any one of claims 1 to 3, is characterized in that, also comprise pharmaceutically acceptable carrier.

5. the external used medicine for improving myopia according to claim 4, it is characterized in that, described medicine is patch or unguentum.

6. the preparation method of the external used medicine for improving myopia according to claim 5, is characterized in that, comprise the following steps:

7. the preparation method of the external used medicine for improving myopia according to claim 6, is characterized in that, further comprising the steps of:

Add pharmaceutically acceptable carrier, be made into patch, oil preparation or unguentum.

8. the application of external used medicine according to claim 5 in improvement, treatment myopia.

9. improve the method for myopia, it is characterized in that, comprise the following steps:

(2) by drug effect according to claim 5 in particular acupoint 12 ~ 24 hours, with by the silting in Liver Channel, urinary bladder channel, spleen channel cleaning human body, described particular acupoint refer in Jingming acupoint, Yintang acupoint, SIBAI point, Tongziliao acupoint, yang white cave, the bright cave of nebula, outer photohole, point Hegu and TAICHONG acupoint one or more;

(3) temper eye muscle every day 1 ~ 5 time, described exercise eye muscle is: