CN104984239A - Chinese herbal medicament for treating tetanus - Google Patents

Abstract

The invention disclose Chinese herbal medicament for treating tetanus. The medicament is prepared from the following main raw materials according to weight proportion: 10-18 parts of turmeric root-tuber, 8-15 parts of herb of sessile lobelia, 9-16 parts of incised notopterygium, 11-15 parts of castor root, 7-14 parts of root of shortlobe ligusticum, 9-15 parts of bamboo juice, 10-16 parts of jackinthepulpit tuber, 12-17 parts of all grass or root of common calanthe, 9-13 parts of drumfish bladder, 7-13 parts of periostracum cicada, 3-6 parts of scorpion, 10-15 parts of Taiwan beautyberry leaf, 12-16 parts of herb of diversifolious hemiphragma, 8-12 parts of szechuan lovage rhizome and 11-16 parts of herb of cavalerie mosla. The Chinese herbal medicament is prepared by combining multiple years of clinical practices, has the efficacy of calming the nerves, relieving spasm, promoting blood and qi circulation, dredging the meridians, relieving a cough and eliminating phlegm, and has an obvious curative effect on treating tetanus.

Description

Treat tetanic Chinese medicine

Technical field

The present invention relates to traditional Chinese medicine field, especially relate to one and treat tetanic Chinese medicine.

Background technology

Tetanus is after invading human body wound by clostridium tetani, growth and breeding under anaerobic environment, produces and to cause addicted to neural extracellular toxin whole-body muscle tonic spasm to be the acute infectious disease of feature.Heavy patient's Ke Yin laryngospasm or secondary Severe Pulmonary Infection and dead.Tetanus neonatorum is caused by infection of navel cord, and case fatality rate is very high.The whole world has nearly 1,000,000 tetanus cases every year according to estimates, and hundreds thousand of neonate dies from tetanus.

Tetanus is normal and a kind of specific infection of being associated of wound.After may occurring in various wound, also may betide the puerpera given a birth under unclean condition and neonate.Clostridium tetani is present in the intestinal of people and animals at ordinary times, excretes with feces, is distributed in nature with spore state, especially being common in soil.This bacterium has very strong drag to environment, can boiling resistance.The pollution rate of traumatic wounds is very high, and in battlefield, pollution rate can reach 25%-80%.But tetanus sickness rate only accounts for the 1%-2% of polluter, prompting morbidity must have other factors, and principal element is exactly anaerobic environment.During wound, clostridium tetani can pollute deep tissue (as blind pipe wound, deep are stabbed).If wound collar extension is less, there is slough in wound, clot fills, or filling tension, ischemia etc., just define the anaerobic environment that is applicable to the breeding of this bacteria growing.If there is aerobe to infect simultaneously, the latter will consume oxygen residual in wound, makes primary disease be easier to occur.

Tetanic clinical manifestation is the tetanic and clonospasm of whole body skeletal muscle persistence, and severe patient can occur that laryngospasm is suffocated, pulmonary infection and exhaustion.After clostridium tetani invades wound, just can breed rapidly in local and produce toxin under low oxygen conditions.

At present, treating tetanic Chinese medicine has a lot, publication number CN 103705556 A(application number 201310740571.4) the one that patent document discloses treat tetanic Chinese medicine composition, comprise medicine for external use and oral medicine, it is characterized in that, described medicine for external use is triangle Folium Alangii, and described oral medicine is made up of the Chinese medicine of following weight portion: Herba cynodontis 10-30 part, Herba Duchesneae Indicae 10-30 part, Caulis Seu Folium Euonymi Fortunei 10-30 part.The one that patent document discloses of publication number CN 104208552 A (application number 201410428086.8) treats tetanic Chinese medicine preparation, and described Chinese medicine preparation is made up of the Chinese herb of following weight portion: Rhizoma Arisaematis 20-30 gram, Rhizoma Gastrodiae 10-20 gram, Periostracum Cicadae 10-20 gram, Calculus Bovis 10-20 gram, Rhizoma alpiniae chinensis 10-20 gram, Fructus Chaenomelis 10-20 gram, Ramulus Cinnamomi 10-20 gram, Fructus Atriplicis Sibiricae 10-20 gram, Scolopendra 10-20 gram, Fructus Evodiae 8-15 gram, Cornu Saigae Tataricae 8-12 gram, Concretio Silicea Bambusae 8-12 gram, Herba Taraxaci 8-12 gram, Rhizoma Coptidis 8-12 gram, Radix Astragali 8-12 gram.Publication number CN 103735800 A(application number 201310650859.2) the one that patent document discloses treat tetanic Chinese medicine formula, this formula comprises: Fructus Kochiae 15g, fresh pinaster root 1 chi, Bulbus Allii Fistulosi 3g, oxya chinensis 10, Rhizoma Arisaematis 6g, TianXing 9g, Periostracum Cicadae 10g.

Mainly apply antitetanic extract for treating clinically at present, easily causing allergic reaction property disease, as anaphylactic shock, first serum sickness etc., severe patient also wants tracheotomy in patients sometimes, brings larger misery to patient.And the curative effect of existing most medicine is unsatisfactory, need to improve further and improve.

Summary of the invention

For the deficiencies in the prior art, an object of the present invention is to provide the tetanic Chinese medicine for the treatment of of a kind of taking convenience, Be very effective, has spasmolytic of calming the nerves, blood-activating and qi-promoting, ventilation meridian, effect of relieving cough and expelling phlegm, and treatment tetanus is evident in efficacy.Another object of the present invention is just to provide the preparation method of the tetanic Chinese medicine of above-mentioned treatment.

Above-mentioned purpose of the present invention is achieved through the following technical solutions:

Treat tetanic Chinese medicine, take off the primary raw material stating weight proportion and be prepared from: Radix Curcumae 10-18 part; Herba Lobeliae Sessilifoliae 8-15 part; Rhizoma Et Radix Notopterygii 9-16 part; Radix Ricini 11-15 part; Radix Ligustici Brachylobi 7-14 part; Succus Bambusae 9-15 part; Rhizoma Arisaematis 10-16 part; Herba seu Radix Calanthes 12-17 part; Shishou Air Bladder pseudosciaenae seu Acipenser 9-13 part; Periostracum Cicadae 7-13 part; Scorpio 3-6 part; Folium Callicarpae Formosanae 10-15 part; Herba hemipharagmatis heterophylli 12-16 part; Rhizoma Chuanxiong 8-12 part; Herba Moslae Cavaleriei 11-16 part.

Treat tetanic Chinese medicine, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Radix Curcumae 13-15 part; Herba Lobeliae Sessilifoliae 11-13 part; Rhizoma Et Radix Notopterygii 12-14 part; Radix Ricini 13-14 part; Radix Ligustici Brachylobi 10-12 part; Succus Bambusae 11-13 part; Rhizoma Arisaematis 12-14 part; Herba seu Radix Calanthes 14-16 part; Shishou Air Bladder pseudosciaenae seu Acipenser 10-12 part; Periostracum Cicadae 9-11 part; Scorpio 4-5 part; Folium Callicarpae Formosanae 12-14 part; Herba hemipharagmatis heterophylli 13-15 part; Rhizoma Chuanxiong 9-11 part; Herba Moslae Cavaleriei 13-15 part.

Treat tetanic Chinese medicine, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from :radix Curcumae 14 parts; Herba Lobeliae Sessilifoliae 12 parts; Rhizoma Et Radix Notopterygii 13 parts; Radix Ricini 13.5 parts; Radix Ligustici Brachylobi 11 parts; Succus Bambusae 12 parts; Rhizoma Arisaematis 13 parts; Herba seu Radix Calanthes 15 parts; 11 parts, Shishou Air Bladder pseudosciaenae seu Acipenser; Periostracum Cicadae 10 parts; Scorpio 4.5 parts; Folium Callicarpae Formosanae 13 parts; Herba hemipharagmatis heterophylli 14 parts; Rhizoma Chuanxiong 10 parts; Herba Moslae Cavaleriei 14 parts.

Present invention also offers the preparation method tetanic for above-mentioned treatment Chinese medicine being made pharmaceutically acceptable tablet, granule, thick paste agent, pill and injection.

The preparation method of the tetanic Chinese medicine tablet of described treatment, step is as follows:

(1) Scorpio is put into crock, add jowar wine, sealing is soaked 10-20 hour (preferably 13-17 hour is soaked in sealing, is more preferably sealing immersion 15 hours), and filter, filtrate is for subsequent use, and the Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, being concentrated into relative density is 1.12-1.16(55 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.15, be more preferably and be concentrated into the thick paste that relative density is 1.14), granulate, tabletting, dry, sugar coating.

Instructions of taking: each 1-2 sheet, every day 3 times, 3 days courses for the treatment of.

The preparation method of the tetanic Chinese medicine of above-mentioned treatment, the consumption of the preferred jowar wine of step (1) is 3-5 times of Scorpio quality, and the consumption being more preferably jowar wine is 4 times of Scorpio quality.

The preparation method of the tetanic Chinese medicine granule of described treatment, step is as follows:

(1) Scorpio is put into crock, (consumption of preferred jowar wine is 3-5 times of Scorpio quality to add jowar wine, the consumption being more preferably jowar wine is 4 times of Scorpio quality), sealing soaks 10-20 hour, and (preferably 13-17 hour is soaked in sealing, be more preferably sealing immersion 15 hours), filter, filtrate is for subsequent use, Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, being concentrated into relative density is 1.12-1.16(55 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.15, be more preferably and be concentrated into the thick paste that relative density is 1.14), make uniform fine particle, be aided with pharmaceutically acceptable carrier package, every parcel 6g.

Instructions of taking: each 1 bag, takes after dissolving, every day 3 times, 3 days courses for the treatment of by the warm waters of about 35 DEG C.

The preparation method of described treatment tetanic Chinese medicine thick paste agent, step is as follows:

(1) Scorpio is put into crock, (consumption of preferred jowar wine is 3-5 times of Scorpio quality to add jowar wine, the consumption being more preferably jowar wine is 4 times of Scorpio quality), sealing soaks 10-20 hour, and (preferably 13-17 hour is soaked in sealing, be more preferably sealing immersion 15 hours), filter, filtrate is for subsequent use, Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, being concentrated into relative density is 1.12-1.16(55 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.15, be more preferably and be concentrated into the thick paste that relative density is 1.14), mix homogeneously, sterile packaged.

Instructions of taking: each 6-10ml, every day 2-3 time, 3 days courses for the treatment of.

The preparation method of the tetanic Chinese medicine pill of described treatment, step is as follows:

(1) Scorpio is put into crock, (consumption of preferred jowar wine is 3-5 times of Scorpio quality to add jowar wine, the consumption being more preferably jowar wine is 4 times of Scorpio quality), sealing soaks 10-20 hour, and (preferably 13-17 hour is soaked in sealing, be more preferably sealing immersion 15 hours), filter, filtrate is for subsequent use, Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, being concentrated into relative density is 1.12-1.16(55 DEG C) thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.15, be more preferably and be concentrated into the thick paste that relative density is 1.14), dry, pulverize, obtain medicated powder;

(6) Mel is placed in pot, tempers with slow fire, wait Mel to endure to thick, add step (5) gained medicated powder, fully mix into ointment thoroughly, make pill (preferred diameter is 3mm-5mm, and being more preferably diameter is 4mm) by traditional Chinese medical science tradition pill method.

The preparation method of the tetanic Chinese medicine pill of above-mentioned treatment, the consumption of the preferred Mel of step (6) is the 30%-40% of medicated powder quality, and the consumption being more preferably Mel is 35% of medicated powder quality.

Instructions of taking: each 10-15 ball, every day 2-3 time, 3 days courses for the treatment of.

The preparation method of the tetanic Chinese medicine injection of described treatment, step is as follows:

(1) Scorpio is put into crock, (consumption of preferred jowar wine is 3-5 times of Scorpio quality to add jowar wine, the consumption being more preferably jowar wine is 4 times of Scorpio quality), sealing soaks 10-20 hour, and (preferably 13-17 hour is soaked in sealing, be more preferably sealing immersion 15 hours), filter, filtrate is for subsequent use, Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, add activated carbon adsorption, filtering decarbonization, use 0.22um metre filter, sterilizing at 120-130 DEG C, sterile packaged.

Instructions of taking: each 5-8ml of intramuscular injection, every day 2 times, 3 days courses for the treatment of or each 15-20ml of intravenous drip, every day 1 time, 3 days courses for the treatment of.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian.For the dried root of zingiberaceous plant RADIX CURCUMAE, Rhizoma Curcumae Longae, Guangxi zedoary or Rhizoma Curcumae.There is regulating qi to disperse stagnation, heart fire-clearing upset-relieving, effect of promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.

Herba Lobeliae Sessilifoliae: acrid in the mouth, property is put down.Return lung, kidney channel.For root or the whole herb with root of campanulaceae lobelia plant Herba Lobeliae Sessilifoliae.Containing multiple alkaloids such as antabacs, separately containing sessilifolan, ursolic acid, nonacosane, melissic acid.There is expelling phlegm for arresting cough, inducing diuresis to remove edema, effect of heat-clearing and toxic substances removing.For cold, fever, cough phlegm dyspnea, liver tough words ascites, edema, carbuncle furunculosis, Serpentis lyssodexis, honeybee stings.

Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature.Return bladder, kidney channel.For dry rhizome and the root of samphire Rhizoma Et Radix Notopterygii or Radix et Rhizoma Notopterygii.There is cold expelling, dispel the wind, dehumidifying, effect of pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.

Radix Ricini: acrid in the mouth, property is put down.GUIXIN, Liver Channel.For the root of Euphorbiaceae Ricinus plant Semen Ricini.Containing trans-2-decene-4,6,8-tri-ynoic acid methyl ester, 1-tridecylene-3,5,7,9,11-five alkynes, cupreol etc.There is expelling wind to relieve convulsion, effect of promoting blood circulation and detumescence.For tetanus, epilepsy, rheumatic arthralgia, paralysis, carbuncle scrofula, traumatic injury, proctoptosis, uterine prolapse, traumatic hemorrhage.

Radix Ligustici Brachylobi: acrid in the mouth, micro-sweet, slightly warm in nature.Return lung, bladder, spleen channel.For the root of Umbelliferae Peucedanum plant ring Radix Peucedani.Have and deliver analgesia, effect of expelling wind and dampness.For diseases caused by exogenous pathogenic factor exterior syndrome, have a headache giddy, arthralgia, spasm of the limbs, conjunctival congestion, the disease such as skin infection and tetanus.

Succus Bambusae: sweet in the mouth, hardship, cold in nature.GUIXIN, liver, lung meridian.For the juice that the stem of grass family Phyllostachys plant phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle etc. flows out after baking.The fresh Succus Bambusae water-soluble portions such as phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle contain aspartic acid, methionine, serine, proline etc. 13 seed amino acid; Still containing cystine in the early Succus Bambusae such as bamboo, benzoic acid, salicylic acid etc.There is resolving heat and reducing pathogenic fire, effect of sliding expectorant profit key.For middle wind-phlegm fan, lung-heat expectorant is stopped up, infantile convulsion, epilepsy, calentura abundant expectoration, high fever excessive thirst, restlessness during pregnancy, tetanus.

Rhizoma Arisaematis: bitter in the mouth, pungent, warm in nature.Return lung, liver, spleen channel.For aroid Rhizoma Arisaematis, different leaf are without the dry tuber of Rhizoma Arisaematis or arisaema amurense Maxim.There is drying dampness to eliminate phlegm, expelling wind and relieving convulsion, effect of mass dissipating and swelling eliminating.For pertinacious phlegm cough, paralysis is dizzy, and middle wind-phlegm is stopped up, and mouth limit is crooked, hemiplegia, epilepsy, infantile convulsion, tetanus.Life uses external treatment carbuncle, snake bite and insect sting.

Herba seu Radix Calanthes: acrid in the mouth, micro-hardship, cold nature.For herb or the rhizome of the orchid family Calanthe plant calanthe.Fresh rhizome is containing indoles and glucosides thereof: calanthe glycosides A, B, dihydro phenanthrene derivative, indican, calanthe luxuriant and rich with fragrance alcohol, Ryukyu's calanthe glycosides; Indoles alkaloid class: couroupitine A, indirubin etc.There is heat-clearing and toxic substances removing, effect of promoting blood circulation and stopping pain.For carbuncle, laryngopharynx swelling and pain, hemorrhoid, rheumatic arthralgia, traumatic injury.

Shishou Air Bladder pseudosciaenae seu Acipenser: be the Air Bladder pseudosciaenae seu Acipenser of Sciaenidae animal Carnis Pseudosciaenae or Carnis Pseudosciaenae.Carnis Pseudosciaenae has another name called Channa argus, mainly lives in the seabed of high concentration of sediment, and major part crosses group life.Carnis Pseudosciaenae mainly with shell-fish and Mollusca for food.Every 100 grams of large and small Channa argus contain respectively: moisture 81,79 grams; 17.6,16.7 grams, protein; 0.8,3.5 gram, fat; Ash 0.9,0.9 gram; Calcium 33,43 milligrams; 135,127 milligrams, phosphorus; Ferrum 0.9,1.2 milligrams; Thiamine 0.01,0.01 milligram; 0.10,0.14 milligram, riboflavin; Nicotinic acid 0.8,0.9 milligram.Every 1 kilogram of fresh Carnis Pseudosciaenae is containing iodine 120 microgram.

Periostracum Cicadae: sweet in the mouth, cold in nature.Return lung, Liver Channel.Exuviae shell when nymph for cicada Cryptotympana atrata Fabr. sprouts wings.There is loose wind heat extraction, sore-throat relieving, rash, nebula removing, effect of spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion buckwheat hinders, convulsion with spasms, tetanus.

Scorpio: acrid in the mouth, property is put down.Return Liver Channel.For the dry body of Buthidae animal Scorpio.There is endogenous wind stopping spasmolytic, dispersing pathogen accumulation, effect of removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port (wai), hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.

Folium Callicarpae Formosanae: different name cercis, Folium Callicarpae Formosanae.Bitter in the mouth, puckery, cool in nature.For the leaf of Verenaceae Callicarpa plant callicarpa pedunculata, Callicarpa dichotoma, callicarpa cathayana Chang, Radix Callicarpae Giraldii.The fresh leaf of callicarpa pedunculata contains flavones ingredient 3,5,7,4 '-tetramethoxy flavones; 3,5,7,3 ' ,4 '-pentamethoxyl flavone; 5-hydroxyl-3,4,7,3 '-tetramethoxy flavones; 3,4,7,3 '-tetramethoxy flavones.Also containing triterpenes components: ursolic acid, 2 α, 3 alpha-dihydroxy-Usu alkene-28-acid.Again containing phytosterol and glycoside thereof, condensed tannin, resinene, saccharide and magnesium, calcium, iron salt etc.There is astringing to arrest bleeding, effect of heat-clearing and toxic substances removing.For hematemesis, spitting of blood, epistaxis, gingival hemorrhage, hematuria, has blood in stool, metrorrhagia, skin purpura, traumatic hemorrhage, swollen ulcer drug, venom, burn.

Herba hemipharagmatis heterophylli: taste is micro-sweet, light, warm in nature.GUIXIN, Liver Channel.For the herb of Scrophulariaceae Herba hemipharagmatis heterophylli platymiscium Herba hemipharagmatis heterophylli.There is expelling wind and removing dampness, heat-clearing and toxic substances removing, effect of promoting blood circulation and stopping pain.For rheumatic arthralgia, amenorrhea is suffered from abdominal pain, scrofula, and skin ulcer swells noxious dampness, pharyngalgia, gingivitis, traumatic injury.

Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, heart channel.For the dry rhizome of samphire Rhizoma Chuanxiong.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea ， mass in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.

Herba Moslae Cavaleriei: acrid in the mouth, warm in nature.For the herb of Labiatae stone mustard thuja platymiscium little Hua mustard thuja.There is diaphoresis expelling summer-heat, effect of eliminating damp, detoxifying.For flu, heatstroke, vomiting, has loose bowels, edema, eczema, sore swollen toxin, herpes zoster, carbuncle of yin nature scrofula, traumatic pain, venom.

Beneficial effect of the present invention is mainly reflected in the following aspects:

1, to combine clinical practice for many years formulated for the tetanic Chinese medicine of this treatment, has effect of spasmolytic of calming the nerves, blood-activating and qi-promoting, ventilation meridian, relieving cough and expelling phlegm, and treatment tetanus is evident in efficacy.

2. the Chinese medicine ingredients safe without toxic side effect that the present invention is used, can avoid treating the misery that tetanus carries out treatment of wounds and operation increase patient.

3, medicament of the present invention is based on the tetanic principle of Chinese traditional treatment, is to make on the basis that have studied lot of documents, pharmacology work and clinical trial, Be very effective.

4, this medicament selected materials great majority are Chinese medicine material, and medicine source is easy to get, with low cost, can not bring large financial burden to patient.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.

embodiment 1treat tetanic Chinese medicine, take off the primary raw material stating weight proportion and be prepared from (getting 80g for every part): Radix Curcumae 10 parts; Herba Lobeliae Sessilifoliae 8 parts; Rhizoma Et Radix Notopterygii 9 parts; Radix Ricini 11 parts; Radix Ligustici Brachylobi 7 parts; Succus Bambusae 9 parts; Rhizoma Arisaematis 10 parts; Herba seu Radix Calanthes 12 parts; 9 parts, Shishou Air Bladder pseudosciaenae seu Acipenser; Periostracum Cicadae 7 parts; Scorpio 3 parts; Folium Callicarpae Formosanae 10 parts; Herba hemipharagmatis heterophylli 12 parts; Rhizoma Chuanxiong 8 parts; Herba Moslae Cavaleriei 11 parts.

The preparation method of the tetanic Chinese medicine tablet of above-mentioned treatment, step is as follows:

(1) Scorpio is put into crock, add jowar wine (consumption is 4 times of Scorpio quality), sealing immersion 15 hours, filter, filtrate is for subsequent use, and the Scorpio after immersion is taken out, and dries stand-by;

(2) be placed in hot pot by Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae, moderate heat fries 13 minutes, together grinds to form smalls with step (1) gained Scorpio, crosses 140 mesh sieves;

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 8 hours;

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 3 hours, add step (3) gains, decoct twice, each decoction 45 minutes, merging filtrate, add step (2) gained medicated powder, mixing, places after 3 hours and filters, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, being concentrated into relative density is 1.14(55 DEG C) thick paste, granulate, tabletting, dry, sugar coating.

Instructions of taking: each 2, every day 3 times, 3 days courses for the treatment of.

embodiment 2treat tetanic Chinese medicine, take off the primary raw material stating weight proportion and be prepared from (getting 20g for every part): Radix Curcumae 18 parts; Herba Lobeliae Sessilifoliae 15 parts; Rhizoma Et Radix Notopterygii 16 parts; Radix Ricini 15 parts; Radix Ligustici Brachylobi 14 parts; Succus Bambusae 15 parts; Rhizoma Arisaematis 16 parts; Herba seu Radix Calanthes 17 parts; 13 parts, Shishou Air Bladder pseudosciaenae seu Acipenser; Periostracum Cicadae 13 parts; Scorpio 6 parts; Folium Callicarpae Formosanae 15 parts; Herba hemipharagmatis heterophylli 16 parts; Rhizoma Chuanxiong 12 parts; Herba Moslae Cavaleriei 16 parts.

The preparation method of the tetanic Chinese medicine granule of above-mentioned treatment, step is as follows:

(1) Scorpio is put into crock, add jowar wine (consumption is 4 times of Scorpio quality), sealing immersion 15 hours, filter, filtrate is for subsequent use, and the Scorpio after immersion is taken out, and dries stand-by;

(2) be placed in hot pot by Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae, moderate heat fries 13 minutes, together grinds to form smalls with step (1) gained Scorpio, crosses 140 mesh sieves;

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 8 hours;

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction 45 minutes, merging filtrate, add step (2) gained medicated powder, mixing, places after 3 hours and filters, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, being concentrated into relative density is 1.14(55 DEG C) thick paste, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, every parcel 6g.

Instructions of taking: each 1 bag, takes after dissolving, every day 3 times, 3 days courses for the treatment of by the warm waters of about 35 DEG C.

model case oneold XX, female, 38 years old, people from Zibo City of Shandong Province.Accidentally cut finger in patient work, use health paper bag at that time once.Processus aboralis sense in 3 days is weak, and the symptom such as whole-body muscle tonic spasm, paroxysmal tic, rapid breathing, gnathospasma is given prominence to gradually, with ictal uncomfortable in chest, whole body is felt nervous, slurred speech.Remove examination in hospital, stiffness of the neck, gnathospasma, Consciousness, cardiopulmonary (-), abdominal muscle, dorsal muscles are nervous, extremity hypermyotonia.Be diagnosed as tetanus, within 5 days, have no in hospitalize and be clearly better.

Take after the present invention treats 1 course for the treatment of of tetanic Chinese medicine, twitch, breathe anxious, gnathospasma symptom and be eased.After continuing to take 2 courses for the treatment of, all malaise symptoms disappear substantially.Later stage visits and learns that recovery is normal completely, does not have recurrence.

embodiment 3treat tetanic Chinese medicine, take off the primary raw material stating weight proportion and be prepared from (every part of 50g): Radix Curcumae 13 parts; Herba Lobeliae Sessilifoliae 11 parts; Rhizoma Et Radix Notopterygii 12 parts; Radix Ricini 13 parts; Radix Ligustici Brachylobi 10 parts; Succus Bambusae 11 parts; Rhizoma Arisaematis 12 parts; Herba seu Radix Calanthes 14 parts; 10 parts, Shishou Air Bladder pseudosciaenae seu Acipenser; Periostracum Cicadae 9 parts; Scorpio 4 parts; Folium Callicarpae Formosanae 12 parts; Herba hemipharagmatis heterophylli 13 parts; Rhizoma Chuanxiong 9 parts; Herba Moslae Cavaleriei 13 parts.

The preparation method of above-mentioned treatment tetanic Chinese medicine thick paste agent, step is as follows:

(1) Scorpio is put into crock, add jowar wine (consumption is 4 times of Scorpio quality), sealing immersion 15 hours, filter, filtrate is for subsequent use, and the Scorpio after immersion is taken out, and dries stand-by;

(2) be placed in hot pot by Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae, moderate heat fries 13 minutes, together grinds to form smalls with step (1) gained Scorpio, crosses 140 mesh sieves;

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 8 hours;

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 3 hours, add step (3) gains, decoct twice, each decoction 45 minutes, merging filtrate, add step (2) gained medicated powder, mixing, places after 3 hours and filters, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, being concentrated into relative density is 1.14(55 DEG C) thick paste, mix homogeneously, sterile packaged.

Instructions of taking: each 10ml, every day 3 times, 3 days courses for the treatment of.

embodiment 4treat tetanic Chinese medicine, take off the primary raw material stating weight proportion and be prepared from (getting 35g for every part): Radix Curcumae 15 parts; Herba Lobeliae Sessilifoliae 13 parts; Rhizoma Et Radix Notopterygii 14 parts; Radix Ricini 14 parts; Radix Ligustici Brachylobi 12 parts; Succus Bambusae 13 parts; Rhizoma Arisaematis 14 parts; Herba seu Radix Calanthes 16 parts; 12 parts, Shishou Air Bladder pseudosciaenae seu Acipenser; Periostracum Cicadae 11 parts; Scorpio 5 parts; Folium Callicarpae Formosanae 14 parts; Herba hemipharagmatis heterophylli 15 parts; Rhizoma Chuanxiong 11 parts; Herba Moslae Cavaleriei 15 parts.

The preparation method of the tetanic Chinese medicine pill of above-mentioned treatment, step is as follows:

(1) Scorpio is put into crock, add jowar wine (consumption is 4 times of Scorpio quality), sealing immersion 15 hours, filter, filtrate is for subsequent use, and the Scorpio after immersion is taken out, and dries stand-by;

(2) be placed in hot pot by Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae, moderate heat fries 13 minutes, together grinds to form smalls with step (1) gained Scorpio, crosses 140 mesh sieves;

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 8 hours;

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 3 hours, add step (3) gains, decoct twice, each decoction 45 minutes, merging filtrate, add step (2) gained medicated powder, mixing, places after 3 hours and filters, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, being concentrated into relative density is 1.14(55 DEG C) thick paste, dry, pulverize, obtain medicated powder;

(6) Mel is placed in pot, tempers with slow fire, wait Mel to endure to thick, add step (5) gained medicated powder, fully mix into ointment thoroughly, make by the traditional Chinese medical science tradition pill method pill that diameter is 4mm.

Instructions of taking: each 10 balls, every day 3 times, 3 days courses for the treatment of.

model case twomodel XX, female, 46 years old, people from Jining City in Shandong Province.When doing housework because of carelessness by the knife injury that gets rusty to hand, just cleared up wound simply at that time.After one week, wound occurs that inflammation is red and swollen, and has occurred typical flesh strong contraction, is masseter at first, after be facial muscle, neck flesh, dorsoventral muscle, extremity muscle group etc. in turn, with violent spasm sample pain, dyspnea sometimes, a large amount of perspiration, removes examination in hospital, is diagnosed as tetanus.Treat after one week without taking a turn for the better.

Take after the present invention treats 1 course for the treatment of of tetanic Chinese medicine, symptom is alleviated to some extent, and wound heals substantially.After continuing to take 2 courses for the treatment of, all malaise symptoms disappear, and reach clinical cure.Later stage visits and learns and fully recover, without recurrence.

embodiment 5treat tetanic Chinese medicine, take off the primary raw material stating weight proportion and be prepared from (getting 40g for every part): Radix Curcumae 14 parts; Herba Lobeliae Sessilifoliae 12 parts; Rhizoma Et Radix Notopterygii 13 parts; Radix Ricini 13.5 parts; Radix Ligustici Brachylobi 11 parts; Succus Bambusae 12 parts; Rhizoma Arisaematis 13 parts; Herba seu Radix Calanthes 15 parts; 11 parts, Shishou Air Bladder pseudosciaenae seu Acipenser; Periostracum Cicadae 10 parts; Scorpio 4.5 parts; Folium Callicarpae Formosanae 13 parts; Herba hemipharagmatis heterophylli 14 parts; Rhizoma Chuanxiong 10 parts; Herba Moslae Cavaleriei 14 parts.

The preparation method of the tetanic Chinese medicine injection of described treatment, step is as follows:

(1) Scorpio is put into crock, add jowar wine (consumption is 4 times of Scorpio quality), sealing immersion 15 hours, filter, filtrate is for subsequent use, and the Scorpio after immersion is taken out, and dries stand-by;

(2) be placed in hot pot by Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae, moderate heat fries 13 minutes, together grinds to form smalls with step (1) gained Scorpio, crosses 140 mesh sieves;

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 8 hours;

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 3 hours, add step (3) gains, decoct twice, each decoction 45 minutes, merging filtrate, add step (2) gained medicated powder, mixing, places after 3 hours and filters, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, add activated carbon adsorption, filtering decarbonization, use 0.22um metre filter, sterilizing at 120-130 DEG C, sterile packaged.

Instructions of taking: each 5-8ml of intramuscular injection, every day 2 times, 3 days courses for the treatment of or each 15-20ml of intravenous drip, every day 1 time, 3 days courses for the treatment of.

test examplethe present invention treats the clinical practice of tetanic Chinese medicine: in July, 2010 in JIUYUE ,-2011, screen 200 routine tetanus patients, before test 2 weeks, Continuous Observation is carried out to this crowd, record symptom and change, be divided into experimental group and matched group two groups (wherein experimental group 150 people, matched group 50 people) at random.Therapeutic Method is: experimental group adopts the present invention to treat tetanic Chinese medicine injection, each 6ml of intramuscular injection, every day 2 times, 3 days courses for the treatment of; Matched group adopts other therapeutic modality, as tetanus antitoxin, the 1st intramuscular or intravenous injection 50000-200000IU, child is identical with adult's consumption, injected dose and interval time is determined with the backsight state of an illness, simultaneously can also by appropriate injection of antitoxin in the tissue of wound circumference; Human tetanus immunoglobulin injection, for buttocks intramuscular injection, does not need to make skin test, must not be used as intravenous injection, 1. preventive dose: child, adult's ampoule 250IU.Wound surface is serious or the seriously polluted person of wound surface is multiplicable, and 2. reference treatment dosage: 3000-6000IU, is finished as early as possible, can multi-point injection.Curative effect determinate standard: cure: all malaise symptoms disappear completely; Effective: all malaise symptoms alleviate or partial disappearance; Invalid: the recurrence of all malaise symptoms without any improvement or later stage.Wherein, effectively comprise cure and effective.

Adopt the matched group of other treatment mode to compare with the curative effect adopting the present invention to treat the experimental group of tetanic Chinese medicine, result is as shown in table 1:

Table 1

Therapeutic effect: as can be seen from Table 1, adopt the present invention to treat the cure rate of tetanic Chinese medicine up to 74.67%, effective percentage 96.67%, inefficiency is only 3.33%; And the cure rate adopting other treatment mode only 38%, effective percentage is 82%, and inefficiency is up to 18%.Can find out that successful that the present invention treats tetanic Chinese medicine is better than the effect of other drug.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or obtain undoubtedly according to the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat tetanic Chinese medicine, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Radix Curcumae 10-18 part; Herba Lobeliae Sessilifoliae 8-15 part; Rhizoma Et Radix Notopterygii 9-16 part; Radix Ricini 11-15 part; Radix Ligustici Brachylobi 7-14 part; Succus Bambusae 9-15 part; Rhizoma Arisaematis 10-16 part; Herba seu Radix Calanthes 12-17 part; Shishou Air Bladder pseudosciaenae seu Acipenser 9-13 part; Periostracum Cicadae 7-13 part; Scorpio 3-6 part; Folium Callicarpae Formosanae 10-15 part; Herba hemipharagmatis heterophylli 12-16 part; Rhizoma Chuanxiong 8-12 part; Herba Moslae Cavaleriei 11-16 part.

2. the tetanic Chinese medicine for the treatment of according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Radix Curcumae 13-15 part; Herba Lobeliae Sessilifoliae 11-13 part; Rhizoma Et Radix Notopterygii 12-14 part; Radix Ricini 13-14 part; Radix Ligustici Brachylobi 10-12 part; Succus Bambusae 11-13 part; Rhizoma Arisaematis 12-14 part; Herba seu Radix Calanthes 14-16 part; Shishou Air Bladder pseudosciaenae seu Acipenser 10-12 part; Periostracum Cicadae 9-11 part; Scorpio 4-5 part; Folium Callicarpae Formosanae 12-14 part; Herba hemipharagmatis heterophylli 13-15 part; Rhizoma Chuanxiong 9-11 part; Herba Moslae Cavaleriei 13-15 part.

3. the tetanic Chinese medicine for the treatment of according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Radix Curcumae 14 parts; Herba Lobeliae Sessilifoliae 12 parts; Rhizoma Et Radix Notopterygii 13 parts; Radix Ricini 13.5 parts; Radix Ligustici Brachylobi 11 parts; Succus Bambusae 12 parts; Rhizoma Arisaematis 13 parts; Herba seu Radix Calanthes 15 parts; 11 parts, Shishou Air Bladder pseudosciaenae seu Acipenser; Periostracum Cicadae 10 parts; Scorpio 4.5 parts; Folium Callicarpae Formosanae 13 parts; Herba hemipharagmatis heterophylli 14 parts; Rhizoma Chuanxiong 10 parts; Herba Moslae Cavaleriei 14 parts.

4., according to the arbitrary described tetanic Chinese medicine for the treatment of of claim 1-3, it is characterized in that, the preparation method of described tablet, step is as follows:

(1) Scorpio is put into crock, add jowar wine, sealing is soaked 10-20 hour (preferably 13-17 hour is soaked in sealing, is more preferably sealing immersion 15 hours), and filter, filtrate is for subsequent use, and the Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae joined in step (4) gained filtrate, mixing, is concentrated into the thick paste that relative density is 1.12-1.16 and (is preferably concentrated into the thick paste that relative density is 1.13-1.15, be more preferably and be concentrated into the thick paste that relative density is 1.14), granulate, tabletting, dry, sugar coating.

5. the preparation method of the tetanic Chinese medicine for the treatment of according to claim 4, is characterized in that: the consumption of the preferred jowar wine of step (1) is 3-5 times of Scorpio quality, and the consumption being more preferably jowar wine is 4 times of Scorpio quality.

6., according to the arbitrary described tetanic Chinese medicine for the treatment of of claim 1-3, it is characterized in that, the preparation method of described granule, step is as follows:

(1) Scorpio is put into crock, (consumption of preferred jowar wine is 3-5 times of Scorpio quality to add jowar wine, the consumption being more preferably jowar wine is 4 times of Scorpio quality), sealing soaks 10-20 hour, and (preferably 13-17 hour is soaked in sealing, be more preferably sealing immersion 15 hours), filter, filtrate is for subsequent use, Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, be concentrated into the thick paste that relative density is 1.12-1.16 and (be preferably concentrated into the thick paste that relative density is 1.13-1.15, be more preferably and be concentrated into the thick paste that relative density is 1.14), make uniform fine particle, be aided with pharmaceutically acceptable carrier package, every parcel 6g.

7., according to the arbitrary described tetanic Chinese medicine for the treatment of of claim 1-3, it is characterized in that, the preparation method of described thick paste agent, step is as follows:

(1) Scorpio is put into crock, (consumption of preferred jowar wine is 3-5 times of Scorpio quality to add jowar wine, the consumption being more preferably jowar wine is 4 times of Scorpio quality), sealing soaks 10-20 hour, and (preferably 13-17 hour is soaked in sealing, be more preferably sealing immersion 15 hours), filter, filtrate is for subsequent use, Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, mixing, is concentrated into the thick paste (be preferably concentrated into the thick paste that relative density is 1.13-1.15, be more preferably and be concentrated into the thick paste that relative density is 1.14) that relative density is 1.12-1.16, mix homogeneously, sterile packaged.

8., according to the arbitrary described tetanic Chinese medicine for the treatment of of claim 1-3, it is characterized in that, the preparation method of described pill, step is as follows:

(1) Scorpio is put into crock, (consumption of preferred jowar wine is 3-5 times of Scorpio quality to add jowar wine, the consumption being more preferably jowar wine is 4 times of Scorpio quality), sealing soaks 10-20 hour, and (preferably 13-17 hour is soaked in sealing, be more preferably sealing immersion 15 hours), filter, filtrate is for subsequent use, Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae joined in step (4) gained filtrate, mixing, is concentrated into the thick paste that relative density is 1.12-1.16 and (is preferably concentrated into the thick paste that relative density is 1.13-1.15, be more preferably and be concentrated into the thick paste that relative density is 1.14), dry, pulverize, obtain medicated powder;

(6) Mel is placed in pot, tempers with slow fire, wait Mel to endure to thick, add step (5) gained medicated powder, fully mix into ointment thoroughly, make pill (preferred diameter is 3mm-5mm, and being more preferably diameter is 4mm) by traditional Chinese medical science tradition pill method.

9. the preparation method of the tetanic Chinese medicine for the treatment of according to claim 8, is characterized in that: the consumption of the preferred Mel of step (6) is the 30%-40% of medicated powder quality, and the consumption being more preferably Mel is 35% of medicated powder quality.

10., according to the arbitrary described tetanic Chinese medicine for the treatment of of claim 1-3, it is characterized in that, the preparation method of described injection, step is as follows:

(1) Scorpio is put into crock, (consumption of preferred jowar wine is 3-5 times of Scorpio quality to add jowar wine, the consumption being more preferably jowar wine is 4 times of Scorpio quality), sealing soaks 10-20 hour, and (preferably 13-17 hour is soaked in sealing, be more preferably sealing immersion 15 hours), filter, filtrate is for subsequent use, Scorpio after immersion is taken out, and dries stand-by;

(2) Shishou Air Bladder pseudosciaenae seu Acipenser and Periostracum Cicadae are placed in hot pot, moderate heat fries 10-15 minute, and (preferred moderate heat fries 12-14 minute, be more preferably moderate heat and fry 13 minutes), together smalls is ground to form with step (1) gained Scorpio, cross 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(3) Herba Lobeliae Sessilifoliae, Radix Ricini, Rhizoma Arisaematis and Rhizoma Chuanxiong are cut into slices, be placed in glass container, add step (1) gained filtrate, flood 6-10 hour (preferably dipping 7-9 hour, is more preferably dipping 8 hours);

(4) Radix Curcumae, Rhizoma Et Radix Notopterygii, Radix Ligustici Brachylobi, Herba seu Radix Calanthes, Folium Callicarpae Formosanae, Herba hemipharagmatis heterophylli and Herba Moslae Cavaleriei are placed in marmite, soak 2-3 hour, add step (3) gains, decoct twice, each decoction (preferably decocts 43-47 minute in 40-50 minute at every turn, be more preferably each decoction 45 minutes), merging filtrate, adds step (2) gained medicated powder, mixing, place after 2-3 hour and filter, obtain filtrate;

(5) Succus Bambusae is joined in step (4) gained filtrate, add activated carbon adsorption, filtering decarbonization, use 0.22um metre filter, sterilizing at 120-130 DEG C, sterile packaged.