CN104981200B - System and method for the vital sign information for determining object - Google Patents

System and method for the vital sign information for determining object Download PDF

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Publication number
CN104981200B
CN104981200B CN201480007177.2A CN201480007177A CN104981200B CN 104981200 B CN104981200 B CN 104981200B CN 201480007177 A CN201480007177 A CN 201480007177A CN 104981200 B CN104981200 B CN 104981200B
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China
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area
label
marker
light
transmission
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CN201480007177.2A
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Chinese (zh)
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CN104981200A (en
Inventor
A·杜比尔钦克
R·诺依曼
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皇家飞利浦有限公司
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Priority to US201361760683P priority Critical
Priority to EP13154017.1A priority patent/EP2762066A1/en
Priority to US61/760,683 priority
Priority to EP13154017.1 priority
Application filed by 皇家飞利浦有限公司 filed Critical 皇家飞利浦有限公司
Priority to PCT/EP2014/052143 priority patent/WO2014122126A1/en
Publication of CN104981200A publication Critical patent/CN104981200A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A61B5/02055Simultaneously evaluating both cardiovascular condition and temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/0261Measuring blood flow using optical means, e.g. infra-red light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • AHUMAN NECESSITIES
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552Details of sensors specially adapted therefor
    • AHUMAN NECESSITIES
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    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/684Indicating the position of the sensor on the body
    • A61B5/6842Indicating the position of the sensor on the body by marking the skin
    • AHUMAN NECESSITIES
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6898Portable consumer electronic devices, e.g. music players, telephones, tablet computers
    • AHUMAN NECESSITIES
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7278Artificial waveform generation or derivation, e.g. synthesising signals from measured signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • AHUMAN NECESSITIES
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    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937Visible markers
    • A61B2090/3945Active visible markers, e.g. light emitting diodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04Constructional details of apparatus
    • A61B2560/0406Constructional details of apparatus specially shaped apparatus housings
    • A61B2560/0412Low-profile patch shaped housings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233Special features of optical sensors or probes classified in A61B5/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/08Sensors provided with means for identification, e.g. barcodes or memory chips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0024Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system for multiple sensor units attached to the patient, e.g. using a body or personal area network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infra-red radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683Means for maintaining contact with the body
    • A61B5/6832Means for maintaining contact with the body using adhesives
    • A61B5/6833Adhesive patches

Abstract

The present invention relates to long-range photo-plethysmographic method and more particularly to a kind of system (1) and method for determining the vital sign information of object (100).The system comprises:Marker (10,10 ', 30,40,50,60,70), it is used to be applied to the skin of the object (104), the marker further include the light (A, B) for being configured as transmission first wave strong point the first label object area (11,11 ', 23,34b, 41,54b, 61b, 71b) and be configured as at transmission second wave length the second of light (C, D) mark object area (12,12 ', 24,35b, 42,55b, 62b, 72b);Probe unit (22) is used to detect the radiation received from the first label object area of the marker and the second label object area;And analytic unit (6), it is used to determine the vital sign information of the object according to the radiation detected from the first label object area and from the second label object area.

Description

System and method for the vital sign information for determining object

Technical field

The present invention relates to a kind of system and method for determining the vital sign information of object.Specifically, of the invention Relate to the optical measurement approach of the vital sign for the object observed by remotely determining.In this background, optics is surveyed Amount also refers to photo-plethysmographic method (PPG), and more specifically refers to pulse oximetry.

Background technology

The vital sign (for example, heart rate (HR), respiratory rate (RR) or blood oxygen saturation) of people is used as the current shape to people The indicant of state and as to the strong prediction objects of serious medical events.Therefore, vital sign in inpatient environment and Clinic Nursing environment is in and is widely monitored in other health, leisure and fitness environment.

A kind of mode for measuring vital sign is plethysmography.Plethysmography is referred in general to organ or body The measurement of the volume change of body portion, and specifically refer to being attributed to as heartbeat is advanced through object each time The detection of the volume change of the cardiovascular pulse wave of body.

Photo-plethysmographic method (PPG) is the light reflectivity or the variation progress of light transmissive time-varying to area-of-interest or volume The optical measuring technique of assessment.PPG absorbs the principle of more light based on blood than surrounding tissue, therefore blood volume is with every The variation of heartbeat is accordingly influenced to transmit and be reflected.In addition to the information about heart rate, PPG waveforms also can include that can be attributed to The information of other physiological phenomenons (for example, breathing).By to the transmissivity at different wave length (typically red and infrared) And/or the assessment of reflectivity, it can determine blood oxygen saturation.

The skin of object is attached to for the heart rate of measurement object and the conventional pulse oximeter of oxygen saturation, For example, finger tip, ear-lobe or forehead.Therefore, they are referred to as " contact " PPG equipment.Typically pulse oximeter includes: Two pole of photoelectricity as the red LED and infrared LED of light source and for detecting the light for having passed through patient tissue Pipe.Commercially available pulse oximeter between being measured with red wavelength and being measured with infrared wavelength rapidly Switching, and thus measure the transmissivity of the same area or volume of tissue at two kinds of different wave lengths.It is multiple that this is referred to as timesharing With.Transmissivity at each wavelength over time gives the PPG waveforms for red wavelength and infrared wavelength.Although connecing Touch PPG is considered as the atraumatic technique on basis, but contact PPG measures experience and gets up usually not pleasant, this is Because pulse oximeter is directly attached to object and any cable all limits mobile freedom.

Currently, contactless, the long-range PPG equipment for non-compulsory measurement has been had been incorporated into.Long-range PPG utilizes remote Light source from object of interest setting, or be radiation source in general.Similarly, also can by detector (for example, camera or Optical detector) it is arranged far from object of interest.Therefore, long-range photo-plethysmographic system and equipment be considered as it is non-compulsory and And it is very suitable for medicine and non-medical daily use.

" the Contactless Multiple Wavelength Photoplethysmographic of Wieringa et al. Imaging:A First Step Toward“SpO2Camera " Technology " (Ann.Biomed.Eng.33,1034- Page 1041,2005) disclose it is a kind of for based on the measurement result of the plethysmographic signal at different wave length come to tissue In arterial oxygen saturation carry out the long-range PPG systems of contactless imaging.The system comprises monochromatic CMOS cameras and tools There are three types of the light sources of the LED of different wave length.Three sections of films of camera sequentially acquisition target.During every section of film, object By the light source illumination with different wave length.Pulse frequency can be determined according to the film at single wavelength, and require in different waves At least two sections of films of strong point determine oxygen saturation.It once only uses a kind of wavelength and executes the measurement in darkroom.Patient's quilt Allow to move between the subsequent measurement at different wave length.Other problems are measurements in dark for non-compulsory medical application It is unpractical with non-medical applications.

Invention content

The object of the present invention is to provide a kind of for determining the life entity of object in a manner of non-compulsory and is economical The improved system and method for reference breath.It is advantageous to provide a kind of system for being operated under ambient light conditions and Method.More advantageously, the system and method make it possible to the parallel of heart rate and oxygen saturation and may measure in real time.

In the first aspect of the present invention, it is proposed that a kind of system for determining the vital sign information of object, including:

Marker, is used to be applied to the skin of the object, and the marker further includes the first label object area and Two label object areas, wherein the first label object area is configured as the light of transmission first wave strong point, second marker Region is configured as the light at transmission second wave length,

Probe unit is used to detect from the first label object area of the marker and second marker The radiation that region receives, and

Analytic unit, be used for according to from it is described first label object area and from the second marker regionally detecting to Radiation determine the vital sign information of the object.

In other aspects of the present invention, the marker for being used in aforementioned system is rendered as including being configured as Second marker area of the first label object area, the light being configured as at transmission second wave length that transmit the light of first wave strong point Domain, and wherein, the marker is suitable for application to the skin of the object.

In other aspects of the present invention, the equipment for being used in aforementioned system be rendered as include:Probe unit, It, which is used to detect from the first of the marker for the skin for being applied to the object, marks object area and the second marker area The radiation that domain receives, wherein the first label object area is configured as the light of transmission first wave strong point, second label Object area is configured as the light at transmission second wave length;And analytic unit, it is used to mark object area according to from described first With from the second marker regionally detecting to radiation determine the vital sign information of the object.

In other aspects of the present invention, it is proposed that a method of the vital sign information for determining object, including Following steps:

Detect the first label object area and the second label object area from the marker for the skin for being applied to the object The radiation received, wherein the first label object area is configured as the light of transmission first wave strong point, second marker Region is configured as the light at transmission second wave length, and

According to from the first label object area and from the second marker regionally detecting to radiation it is described to determine The vital sign information of object.In embodiment, the method further includes that the marker is applied to the object The step of skin.

In the another aspect of the present invention, a kind of computer program including program code unit, the journey are provided Sequence code unit is used to that the step of computer program season computer executes proposed method ought to be executed on computers. In addition, it is proposed that a kind of non-transient computer-readable storage media being wherein stored with such computer program product, it is described Computer program product is executed in the step by processor operation season the method disclosed herein.

The preferred embodiment of the present invention is defined in the dependent claims.It should be appreciated that claimed marker, setting Standby, method, computer program and medium have with the preferred embodiment of claimed system and in the dependent claims The preferred embodiment of definition is similar and/or identical preferred embodiment.

The term " vital sign " used in the background of the invention refers to the physiological parameter of object and derived parameter. Specifically, term " vital sign " includes heart rate (HR) (also sometimes referred to as pulse frequency), (pulse frequency changes heart rate variability Property), fluctuation intensity, perfusion, perfusion indicant, perfusion variability, Traube Hering Mayer waves, respiratory rate (RR), body The concentration (for example, oxygen saturation or glucose level) of temperature, blood pressure and blood and/or the substance in tissue.

The term " vital sign information " used in the background of the invention includes one or more surveys as defined above The vital sign of amount.In addition, term " vital sign information " includes being related to physiological parameter, the data of corresponding waveform trace, or Person relates to the data of the physiological parameter over time for subsequent analysis.

The present invention is based on such ideas:That is, can according to the spatially separated region of the tissue of parallel measurement or Volume determines vital sign information, rather than sequentially measures the same area or volume of tissue at different wavelengths.It changes Yan Zhi, present invention has been found that can according at different, spatially separated region or volume with the light of different wave length Plethysmographic measurements results determines vital sign information.This can be considered as space division multiplexing.Advantage be can around ring It is executed under conditions of the light of border and measures and do not require as proposed in the prior art with the in-order band illumination of different wave length.

According to an aspect of the present invention, marker is suggested including the first label object area and the second label object area, In, the first label object area is configured as the light of transmission first wave strong point, and the second label object area is configured as Penetrate the light at second wave length.Thus the first label object area and the second label object area are defined for described in determination The spatially separated region of vital sign information.Each label object area is configured as the light at transmission different wave length, makes The concentration of substance can be determined based on the comparison to the light at two kinds of different wave lengths by obtaining.Have to the use of marker following excellent Point:That is, specific additional filtering need not be carried out at probe unit.Single probe unit can acquire the letter all required Breath, this is beneficial for low system cost.

Optionally, the marker includes other label object areas for being configured as emitting the light at other wavelength.Feel emerging Interesting wavelength further includes the nonvisible wavelength of electromagnetic radiation, including infrared wavelength and ultraviolet wavelength.

As used in this article, term " wavelength " also refers to the band or wavelength components of wavelength.This should be appreciated that For the spectral limit with limited spectral width.For example, for optical filter, term wavelength refers to the passband of the filter. Therefore, term wavelength is not limited to a single wavelength, but is also used for wave-length coverage, for example, several around centre wavelength receive Rice or tens nanometers of wave-length coverage.In addition, the term wavelength in the background of filter can also refer to an identical filter Multiple discontinuous spectral limits in wave device element.

As used in this article, term " probe unit " refers to the equipment for detecting electromagnetic radiation.Its by with Detection is set to from the first label object area and the radiation received from the second label object area.In preferred embodiment In, the probe unit is the camera for having imaging sensor (for example, CCD or cmos image sensor), and the camera includes The array of light sensitive pixels.The output of the probe unit is referred to as radiation data.For example, the radiation data is over time Image sequence, that is, video flowing.The camera can be monochrome cameras or color camera.RGB image for color camera passes Sensor includes the color filter array with the filter for red, green and blue color channel.When using RGB color When camera, the overall filtering characteristic of system includes that the transmissison characteristic of the label object area and the colour of the camera lead to The filtering characteristic in road.In embodiment, the transmission peak wavelength of the first label object area be in first in RGB channel it It is interior, and the transmission peak wavelength of the second label object area is within second in RGB channel.By correspondingly selecting institute State the transmissison characteristic of label object area, additionally it is possible to detected by the frequency selectivity of RGB camera to support to first marker Region and described second marks being spatially separating for object area.Thereby, it is possible to loosen to the first label object area and described the The requirement of the transmissison characteristic of two label object areas, and reduce system cost.

The radiation received from the first label object area and the second label object area typically comprises two portions Part.First, the light that the radiation received is included at the marker and/or is reflected at the skin surface, that is, do not penetrate The tissue and the light for not carrying the information about the light absorption in the tissue.Secondly, the radiation received includes The light for being penetrated into the skin and being reflected from the organization internal.The second part of the radiation received is attributed in institute The time-varying for stating the interior focusing of tissue is absorbed and/or is transmitted and the intensity with time-varying.The interaction of light and biological tissue is multiple Two-phonon process that is miscellaneous and including (multiple) scattering, backscattering, absorption, transmission and (unrestrained) reflection.Such as make in the background Term " reflection " is not interpreted as being limited to mirror-reflection, but include the light and tissue of aforementioned type interaction and It is arbitrarily combined.

Optionally, the system also includes for sending out the light at the first wave strong point and/or the second wave length Light source, to ensure have the light at enough respective wavelength available.Also optionally, the system comprises control unit, the controls Unit processed enables the probe unit to be operated with its optimum operating point for controlling luminous power, especially so that for example Noise or alternative saturation effect not interference measurement.However, in a preferred embodiment, surrounding environment light is used only in the system.

The analytic unit is configured as visiting according to from the first label object area and from the second label object area What is measured radiates to determine the vital sign of the object.The analytic unit receives the radiation from the probe unit Data.In order to determine the heart rate of the object, to from single marking object area or even only from marker region exterior Skin receive time-varying radiation carry out assessment be enough.However, in order to determine the concentration of substance, for example, for determination Blood oxygen saturation or glucose level require the analysis to the radiation at different wave length as described above.The analysis is single Member assesses the time varying signal from described two spatially separated label object areas, and thus to two kinds of wavelength Concurrently assessed.For example, the light received from the first label object area is fallen in the part for the probe unit In first group of pixel of imaging sensor, and the light from the second label object area is fallen the of described image sensor In two groups of pixels.For better signal-to-noise ratio, the signal of one group of pixel can be combined.

According to preferred embodiment, the system also includes for identifying first marker in the radiation detected The image processing unit in region and the second label object area.Described image processing unit is to be positioned in the probe unit Optional element between the analytic unit.Described image processing unit receives radiation data, example from the probe unit Such as, video flowing.Described image processing unit includes for being identified in the radiation data received at the image of the marker Manage device.For example, the marker have can in the image of the video flowing identified specific features.Can apply from Analysis method known to image procossing and video analysis.Within the marker, the first label object area and described the Two label object areas are localized.Therefore, described image processing unit provides processed radiation data for the analytic unit, The processed radiation data is included in the radiation data about the first label object area and second label The information of the position of object area.For example, described image processing unit carrys out the radiation for indicating to receive in described image sensor The pixel of part or the group of pixel that mark object area from described first and the radiation received come from second marker area The pixel of the part in domain or the group of pixel are identified respectively.Described image processing unit can be integrated into the analytic unit In.

In other embodiments, system according to the present invention further includes the carrying member for carrying the marker Part.The load-carrying unit is to be at least used to accommodate the firstth area of the first label object area and for accommodating second label Secondth area of object area is characterized.In general, the load-carrying unit can be considered as providing mechanical branch for the marker The element of support, for example, a kind of patch of the skin of the object, label or similar structure can be attached to.It is described Load-carrying unit can be by including that material below or one group of material are made:Paper, fabric, rubber or for patch (particularly for The patch of medical application) other materials.

In another embodiment, the load-carrying unit further includes the institute for the load-carrying unit to be attached to the object State the binder of skin.Since the load-carrying unit is directly attached to the skin of the object in a preferred embodiment, Therefore using the binder of bio-compatible.

In still another embodiment, the first label object area and/or the second label object area include being attached to To the optical filter disk of the load-carrying unit.The optical filter disk ensures only with desired wavelength or wavelength band Light is transmitted.The type of filter panel includes absorbing filter and dielectric filter.Advantageously, the load-carrying unit includes opening Mouth and the optical filter disk being positioned in the opening.The opening is also known as window or optical window.

According to alternative embodiment, the marker, which is included in the first label object area, is applied to the object The skin the first dyestuff and/or the skin that is applied to the object in the second label object area Second dyestuff.As the replacement to using optical filter disk, which uses coloured dye, wherein first dyestuff Transmit the light at the light of first wave strong point and second dyestuff transmission second wave length.Although the optical filter disk is typical Ground is attached to the carrier element, but the dyestuff can be applied directly to the skin of the object without Carrier element.

In other embodiments, the marker further includes the reference zone for having predefined reflection characteristic.The reference Region can be used in calibrating the probe unit, this is because the reflection characteristic for the preset range of wavelength is known.Tool For body, when the system is equipped with optional light source and control unit, the reference zone in the radiation detected It can be used in adjusting sensitivity and/or the power for adjusting the light source and/or the spectrum of the probe unit.The marker Can also include more than one reference zone, wherein each reference zone has different reflection characteristics.For example, red ginseng The reference zone that examination district domain is used to determine the luminous power in red spectrum area, and reflect infrared light is used to determine the light in infrared range Power.Based on these measurement results, the sensitivity of the probe unit can be adjusted.Alternatively, time of measuring is adjusted to realize Good signal-to-noise ratio enough.

Other aspects according to this embodiment, the reference zone is opaque.In other words, the reference zone blocking By any light of the marker, but only the light being incident on the reference zone is reflected.This ensures from the ginseng The radiation that examination district domain receives is substantially interference-free, especially not by the radiation from following Tissue reflectance or backscattering Interference.Therefore, the light from the first label object area and/or the second label object area provides plethysmography information, And the light from the reference zone does not carry plethysmography information and serves as reference.

In addition, the reference zone can be used in determining that any time interference of surrounding environment light or artificial light source or spectrum are dry It disturbs, for example, the systematic influence of flicker or the pulsewidth modulation of slowly varying or such as light source the 50/60Hz during daytime.From The intensity that the first label object area and/or the second label object area measure can be mended for such interference It repays.

In still another embodiment, the marker further includes graphic style.The graphic style is suitable for can be by described point Analysis unit is detected by optional described image processing unit in the radiation data.Preferably, described image pattern has There is high picture contrast, for example, black and white pattern.Alternatively, the graphic style includes that can be clearly distinguished not Same color.Expediently, the graphic style be optimised for it is machine readable, for example, bar code, matrix bar code, alphanumeric Character, QR codes etc..For described image processing unit, specified graphic style is detected in observed scene and is not referred to than analysis Fixed characteristics of image is easier.Optionally, the graphic style is the machine readable code for storing information, for example, for that will survey The vital sign information obtained is assigned to patient's identifier of the body part of patient or the patient.Encoded information can wrap Include for for determine configuration data that the system of vital sign information configured (such as, it is desirable that sensitivity) or Information of the person about the vital sign information to be measured.Object area is marked to the first label object area and described second Arrangement and the size and/or shape of carrier element can also be considered as graphic style.

Optionally, marker can be manufactured or adjust by the different layers of the marking ink on carrier element or dyestuff 's.The color or opacity of the ink can be regulated so that transmission or the correct intensity of blocking or spectral component.Alternatively Or extraly, graphic style can be printed as the part of the marker.

In other embodiments, the first label object area and/or the second label object area include subregion.It changes Yan Zhi, label object area can be made of multiple smaller sections.For example, subregion and/or the institute of the first label object area The subregion for stating the second label object area is arranged with grid pattern.Which ensure that the first label object area and described second Label object area is not separated too far each other, but general reference numeral object area still covers desired skin area.

The another aspect of the system according to the present invention, the marker further include being contacted with the marker for increasing The object tissue in hemoperfusion stimulant.As explained above, photo-plethysmographic method depends on described group The volume change of blood vessel in knitting.Therefore, in order to increase signal strength, it is desirable to ensure that be applied to life entity in the marker There are enough blood flow in the blood vessel below the marker when levying the object to be determined.

Description of the drawings

With reference to embodiments described just below, these and other aspects of the present invention will be apparent and be explained It is bright.In the following figures:

Fig. 1 shows the exemplary embodiment according to the present invention for determining the system of the vital sign information of object;

Fig. 2 shows the determinations using the system according to the present invention to vital sign information;

Fig. 3 shows the first example of marker;

Fig. 4 shows the second example of marker;

Fig. 5 shows the third example of marker;

Fig. 6 shows the example of the marker with subregion;

Fig. 7 shows the alternative example of the marker with subregion.

Specific implementation mode

Fig. 1 shows according to the present invention for determining that the demonstration of the system 1 of the vital sign information 7 of object 100 is real Apply example.System 1 includes that the marker 10, probe unit 2 and analytic unit 6 of the skin for being applied to object 100 are used as base Plinth component.In this example, using the system of the vital sign information for determining object in clinical setting, in the clinic In environment, object 100 is lain on bed 103.

Marker 10 further includes the first label object area 11 of the light for being configured as transmission first wave strong point and is configured as Transmit the second label object area 12 of the light at second wave length.Probe unit 2 is suitable for detecting the first marker from marker 10 Region 11 and second marks the radiation that object area 12 receives.In this example, probe unit 2 is connected to optical image security Unit 4.Probe unit 2 provides the radiation data 3 for the radiation for indicating to detect in the form of video flowing to image processing unit 4. Image processing unit 4 identifies that the first label object area 11 and second marks object area 12 in radiation data 3.Image processing unit 4 are then connected to analytic unit 6.Image processing unit 4 provides pretreated radiation data 5 to analytic unit 6.In the model In example, pretreated radiation data 5 includes that the first marker is described in which area of the image about the video flowing of radiation data 3 Region 11 and second marks the information of object area 12.Analytic unit 6 then neutralizes the second label according to the first label object area 11 When intensity adjustable in object area 12 determines the vital sign information 7 of object.In this example, vital sign information includes heart rate And blood oxygen saturation.

The first label object area 11 and second marks the image processing unit 4 of object area that can also be integrated into for identification In analytic unit 6.Alternatively, radiation data 3 is supplied directly to analytic unit 6.It in this case, can be by video Label object area is manually selected in the image of stream to determine that the first label object area 11 and second marks object area 12.Alternatively, Object 100 with label 10 must be situated in the precalculated position within the visual field of probe unit 2 so that the first marker Region 11 and second marks object area 12 to be positioned at scheduled position.However, being radiated by what image processing unit 4 carried out It is preferred to the automatic identification of marker 10 in data 3.

In shown example, marker 10 is applied directly to the baring skin of the forehead 101 of object 100.Have The alternate labels object 10 ' of first label object area 11 ' and the second label object area 12 ' is positioned in the left forearm 102 of object 100 Place.The size and shape of marker 10,10 ' can be adjusted according to anatomical location.

The scene is illuminated by such as radiation source of sunlight 7a or artificial light source 7b.Radiation source 7a, 7b directly or Indirectly radiation 8a, 8b are sent out towards object 100.Additionally or alternately, system 1 can also include being sent out towards object 100 The optional system source 7c of light 8c.If ambient enviroment light source 7a, 7b do not provide enough light, or if surrounding environment light The spectrum of source 7a, 7b do not provide enough power at first wave strong point and second wave length, then are outstanding to the use of system source 7c Its is beneficial.

Optional control unit 9 is suitable for controlling the sensitivity of probe unit 2 and/or the power of control system light source 7c.By In the dynamic range of the detector or imaging sensor that are used as probe unit 2 be limited, it is thus possible to must be according to being seen Illuminating position in the scene examined adjusts shutter and electronic migration.System source 7c can be the setting probe unit of control ring The part of the optimum operating point of 2 imaging sensor.It is optimal to refer to that output signal does not have signal wave elimination in the background (clipping), be not present imaging sensor a bulk detector saturation, and at least for first mark object area and/ Or second label the corresponding detector region of object area good signal-to-noise ratio.

Fig. 2 illustrates the determination to the vital sign information of object using the system according to the present invention 1.Fig. 2 shows light Source 21, probe unit 22 and the marker that object area 24 is marked with the first label object area 23 and second.The marker It is applied to the skin histology 104 of object.The tissue includes blood vessel 105.

In this embodiment, light source 21 sends out (profit at least first wave strong point (being indicated using dotted lines) and second wave length Indicated with dotted line) light.First label object area 23 is configured as the light of transmission first wave strong point, wherein the first wave length It is corresponding with the first wave length of light source 21.Second label object area 24 is configured as the light at transmission second wave length, wherein described Second wave length is corresponding with the second wave length of light source 21.Fig. 2 has sketched two light rays A, B and second wave length of first wave strong point Two light rays C, the D at place.Since the first label object area 23 is configured as the light of transmission first wave strong point, ray A warps It crosses marker and is penetrated into the skin 104 of object 100.Some in the light are absorbed within skin 104, while described Some in light are reflected and reach probe unit 22 in the tissue.It absorbs and/or reflection characteristic is time-varying, and Indicate using tissue 104 blood vessel 105 to tissue 104 time-varying perfusion.

Probe unit 22 includes the optical detector for receiving optical device (for example, receiver lens) and forming imaging sensor Or the array 25 of pixel.The light received from the first label object area is imaged at first group of pixel or the first pel array 26 On.Accordingly, the light received from the second label object area 24 is imaged in second group of pixel 27.

Due to being time-varying to the absorption of light in tissue 104, it is incident on the imaging sensor of probe unit 22 Luminous intensity be also time-varying.The when intensity adjustable on pixel region 26 is depicted by curve 28.By curve 29 depict into Penetrate the when intensity adjustable in the group 27 of pixel.

Since the first label object area is configured as only transmiting the light of first wave strong point, as indicated by light C, Light at second wave length without label object area and is not penetrated into tissue.Nevertheless, some in the light can It is scattered back at marker surface and reaches probe unit 22.The light is not modulated by the pulsatile change of blood volume, And provide offset.Therefore, the time-varying that the intensity modulated described by curve 28 is attributed to the first wave strong point in tissue 104 is anti- It penetrates.

Accordingly, the light D at second wave length can pass through the second label object area 24, and the light B of first wave strong point It is blocked.Therefore, the intensity modulated described by curve 29 is attributed to the TVR time variable reflection of the second wave length in tissue 104.

The pulse frequency of object can according to one in curve 28 or 29 when intensity adjustable and be determined directly.However, such as It exemplarily explains below, in order to determine blood oxygen saturation by photo-plethysmographic method, it is desirable that at least two wavelength.

Contact pulse oximeter typically transmits red (R) and infrared (IR) (or more accurately, in some feelings It is near-infrared under condition) the light vascular tissue that passes through object of interest.It can be transmitted simultaneously in a manner of alternately (being switched fast) Detect respective light part (R/IR).In view of respective spectrum part is by oxyhemoglobin (HbO2) and reduced hemoglobin (Hb) it differently absorbs, blood oxygen saturation can finally be handled.Oxygen saturation (SO2) algorithm for estimating can use with it is red The ratio of color part and the related signal of infrared part.In addition, the algorithm is it can be considered that non-pulsating signal component.Typically, PPG signals include DC components and relatively small pulsation AC components.In addition, SO2Estimation is related to being applied to through processing in general Value the calibration factor rule of thumb derived.Typically, which is that basis is related to invasive blood The reference measurements of oxygen saturation measurements result and determination.Since PPG equipment substantially detects the ratio of (spectrum) signal section Rate, the ratio must be converted into typically relating to HbO2With the oximetry value of the ratio of Hb, therefore it is required that calibration because Son.For example, but be not intended to the disclosure is limited, general formula below can be based on to the estimation of blood oxygen saturation:

And PPG equipment is responded only according to the spectrum at least two wavelength to detect HbO indirectly2And Hb.

In general, the intensity curve 28,29 as characteristic signal measured is considered including the comparable constant portion (DC) The part alternation (AC) divided and be superimposed upon on the parts DC.Measured using signal processing, can extract AC part and further The parts AC are compensated for interference.For example, the parts AC of characteristic signal can include basic frequency, the basic frequency can be high The angiokinesis of degree ground instruction object 100, especially heartbeat.Furthermore characteristic signal (the especially parts AC) can indicate other Life parameters.In this contact, the detection to arterial oxygen saturation is the key areas of application.As indicated above, In view of the behavior of the parts AC of the characteristic signals at the distinguishing spectrum part of characteristic signals, artery can be substantially calculated Blood oxygen saturation representative value.In other words, it can reflect arterial oxygen saturation in the different radiation absorptions at blood vessel Degree.Furthermore it is possible to add in the fact that also significant changes on different spectrum parts to the absorption difference for being attributed to oxidation level To use.In addition, the parts DC of signal also can be used in blood oxygen saturation detection.Typically, DC representation in components tissue, venous blood With the overall light absorption of non-pulsating arterial blood.In contrast, AC components can indicate the absorption of pulsatile arterial blood.Therefore, to dynamic Arteries and veins blood oxygen saturation (SaO2) be determined to be expressed as:

Wherein, C is calibration parameter.C can represent many kinds of calibration parameters that can be applied to AC/DC relationships, and therefore It should be understood with the stringent algebraically meaning of formula (2).For example, C can indicate fixed constant value, one group it is fixed often Number or adjustable calibration parameter.By way of example, another demonstration SaO2Deriving model can be expressed as:

Wherein, C1And C2It can be considered as the calibration parameter of linear approximation.In an exemplary embodiment, signal calibration is joined Number is determined to be instructed as to parameter C1It is adjusted or adjusts.Furthermore alternatively, SaO2Deriving can also be based on being placed in The numerical value tables of (or can be accessed by equipment 1) in equipment 1.Numerical value tables (or database) can provide the PPG letters to detecting The discrete representation of relationship number between desired calibration parameter.In this case it is also possible to the calibration ginseng that application can adjust It counts to enhance the accuracy of life parameters determination.

It should be appreciated that formula (2) and (3) main purpose for being proposed for explanation.They are not necessarily to be construed as to this public affairs The limitation for the range opened.In fact, technical staff can determine and establish other SaO appropriate2Derive model.Foundation will be detected The substance of survey can use alternative wavelength combination (for example, green and red).Although being described in detail to SaO2Survey Amount, but the example of this universal that should be understood as the concentration for measuring blood and/or the substance in tissue.

Fig. 3 shows the label used in the system 1 according to the present invention for determining the vital sign information of object The more detailed embodiment of object.Marker 30 is with the first graphic style 32;Second graph pattern 33;Reference zone 34a, 35a, 36a、37a;It is configured as label object area 34b, 35b, 36b and the clear mark object area of the light at three kinds of different wave lengths of transmission Domain 37b is characterized.

31 bearing mark object 30 of carrier element and its element, and mechanical stability is provided.In this embodiment, carrier member Part 31 is the patch or adhesive bandage for the skin that object 100 can be directly attached to using binder.Carrier element is by impermeable The opaque rubber-like material for penetrating light is made.Therefore, carrier element is at the position of label object area 34b, 35b, 36b, 37b Opening or window be characterized.

Optical filter disk is placed in each of window 34b, 35b, 36b, wherein filter panel 34b is configured To transmit the light of first wave strong point, filter panel 35b is configured as the light at transmission second wave length, and filter panel 36b is configured For the light at transmission third wavelength.Object area 37b is marked not have frequency selective filter but be transparent, enabling Skin under the 37b of region is considered as to the non-filtered reference of skin by probe unit.

Reference zone 34a, 35a, 36a are the reference zones for specific wavelength.Preferably, the color of reference zone corresponds to In the transmission peak wavelength of neighbor filter.For example, marked region 34b is configured as transmission feux rouges and reference zone 34a is with red Color so that reference zone 34a potentially acts as reference, especially available to being incident on how many feux rouges in the radiation on marker Reference.

Graphic style 32 serves as alignment indicant.Geometry makes image processing unit 4 can determine marker 30 Position and/or orientation.In addition, marker 30 is characterized by the machine-readable graphics pattern 33 of QR code forms.The code include about The information of object so that identified vital sign information can be assigned to object, for example, being assigned to electronic health record (EHR).This yard can also include the information of which position of the body that object is attached to about marker so that for surveying Amount position (such as forehead and arm) is the same time of specificity different measurement results to be taken from same object.

Even if Fig. 3 shows that various features, but not whole feature are all enforceable.Fig. 4 is shown there are two tools Mark the most basic configuration of object area.In this example, marker is included in being directly applied in the first label object area To the second dyestuff of the first dyestuff and the skin for being applied directly to object in the second label object area of the skin of object. The dyestuff can be, for example, to be affixed one's seal, draw, spray or printed on the skin by rubber.The dyestuff quilt of first label object area It is configured to the light of transmission first wave strong point, and the dyestuff at the second label object area is configured as at transmission second wave length Light.Additional reference zone can correspondingly be applied.

Fig. 5 shows the side view of marker similar with the marker presented in Fig. 3.The marker is attached to pair The skin 104 of elephant.Carrier element 51 is that marker 50 provides mechanical stability.In the skin 104 of 51 object-oriented of carrier element Side on, carrier element 51 includes the binder 52 of the skin 104 for carrier element to be attached to object.Binder 52 also wraps Include the stimulant of the hemoperfusion in the tissue 104 for increasing the object contacted with the carrier element 51 with marker 50.

On the opposite side of carrier element 51, marker 50 is with reference zone 54a, 55a and is configured as transmission first The second label object area 55b of first label object area 54b of the light at wavelength and the light being configured as at transmission second wave length It is characterized.This is by being placed in the position of the first label object area and the second label object area and being in turn laminated to carrier member Optical filter disk 56,57 in part 51 is realized.Optionally, binder is not applied in marking object area 54b, 55b, with Just the transmissison characteristic of label object area is not influenced.

Fig. 6 and Fig. 7 shows optical window and reference area with the first label object area and the second label object area The different patterns in domain.In this example, the first label object area and the second label object area are divided into subregion.It can be according to spy Location survey amount needs to select reference zone and the sample of the optical window including the first label object area and the second label object area Formula.

For some measurements, the signal that each wavelength is obtained from the region of tissue closely separated is important.This In the case of, there are several smaller optical windows to be advantageous, for example, according to board design.Fig. 6 is shown with for two kinds The marker 60 of the board design of wavelength, the marker 60 have alternate reference zone 61a and for the of first wave length One marks object area 61b and alternate reference zone 62a and the second label object area 62b for second wave length.For example, For oxygen saturation measurement, red is as first wave length and infrared is as second wave length.

Fig. 7 shows the alternative embodiment of marker 70, wherein reference zone 71a, 72a and be directed to the first marker The distribution of the optical window of region 71b, the second label object area 72b is optimized according to expected signal strength.For example, first It is required that wavelength (for example, green) at the wavelength (for example, red) that is required than second of signal at signal it is stronger.Therefore, always Second label object area 72b of body is increased relative to the first overall label object area 71b, with real at all two kinds of wavelength Existing similar signal strength.

By way of example, the present invention can be applied to health care (for example, non-compulsory remote patient monitoring), lead to In field with monitoring, safety monitoring and so-called life style environment (for example, health and fitness facilities etc.).Using can include: The monitoring that oxygen saturation (pulse oximetry), heart rate, blood pressure, heart output and hemoperfusion are changed;To autonomic function Evaluation;And the detection of human peripheral blood pipe disease.

It is such to illustrate and retouch although illustrating and describing the present invention in detail in the drawings and the preceding description It should be considered as n-lustrative or exemplary to state, and not restrictive.The present invention is not limited to the disclosed embodiments.This field Technical staff is when putting into practice claimed invention it will be appreciated that simultaneously real by studying attached drawing, disclosure and claim Existing other variants of the disclosed embodiments.

In detail in the claims, one word of " comprising " is not excluded for other elements or step, and word "a" or "an" is not It excludes multiple.The function of several recorded in the claims may be implemented in discrete component or other units.Although mutually not It is identical to be recited in mutually different dependent certain measures, but this does not indicate that the group that these measures cannot be used to advantage It closes.

Computer program can be stored/distributed on suitable non-transitory media, for example, together with other hardware or making For optical storage medium or solid state medium that the part of other hardware is supplied, but can also be distributed otherwise, for example, Via internet or other wired or wireless communication systems.

Any reference numeral in claim is all not necessarily to be construed as the limitation to range.

Claims (15)

1. the system (1) of vital sign information (7) of the one kind for determining object (100), including:
Marker (10,10 ', 30,40,50,60,70) is used to be applied to the skin (104) of the object, the marker Further include the first label object area (11,11 ', 23,34b, 41,54b, 61b, 71b) and second label object area (12,12 ', 24, 35b, 42,55b, 62b, 72b), wherein the first label object area is configured as the light (A, B) of transmission first wave strong point, institute The light (C, D) that the second label object area is configured as at transmission second wave length is stated,
Probe unit (2,22) is used to detect the first label object area from the marker and second label The radiation that object area receives, and
Analytic unit (6) is used for according to the spy from the first label object area and from the second label object area What is measured radiates to determine the vital sign information of the object.
2. system according to claim 1 further includes for identifying first marker area in the radiation detected Domain (11,11 ', 23,34b, 41,54b, 61b, 71b) and it is described second label object area (12,12 ', 24,35b, 42,55b, 62b, 72b) image processing unit (4).
3. system according to claim 1 further includes for carrying the carrier element of the marker (31,51).
4. system according to claim 3, wherein the carrier element (31,51) further includes for the carrier is first Part is attached to the binder (52) of the skin (104) of the object (100).
5. system according to claim 3, wherein it is described first label object area (11,11 ', 23,34b, 41,54b, 61b, 71b) and/or the second label object area (12,12 ', 24,35b, 42,55b, 62b, 72b) include be attached to it is described The optical filter disk (56,57) of carrier element (31,51).
6. system according to claim 1, wherein the marker (40) is included in the first label object area (41) In the first dyestuff of the skin for being applied to the object and/or being answered in second label object area (42) Use the second dyestuff of the skin of the object.
7. system according to claim 1, wherein the marker (30,40,60,70) further include have it is predefined The reference zone (34a, 35a, 36a, 54a, 55a, 61a, 62a, 71a, 72a) of reflection characteristic.
8. system according to claim 7, wherein the reference zone is opaque.
9. system according to claim 1, wherein the marker further includes graphic style (32,33).
10. system according to claim 1, wherein the first label object area (61b, 71b) and/or described second It includes subregion to mark object area (62b, 72b).
11. system according to claim 1, wherein the marker further includes for increasing and the marker (50) The stimulant (52) of hemoperfusion in the tissue (104) of the object (100) of contact.
12. one kind for used in system according to claim 1 (1) marker (10,10 ', 30,40,50,60, 70), including:
- the first label object area (11,11 ', 23,34b, 41,54b, 61b, 71b), be configured as transmission first wave strong point Light (A, B),
- the second label object area (12,12 ', 24,35b, 42,55b, 62b, 72b), be configured as transmission second wave length at Light (C, D), and
Wherein, the marker is suitable for application to the skin (104) of the object (100).
13. equipment of the one kind for being used in system according to claim 1 (1), including:
Probe unit (2,22) is used to detect the marker from the skin (104) for being applied to the object (100) (10,10 ', 30,40,50,60,70) first label object area (11,11 ', 23,34b, 41,54b, 61b, 71b) and second mark Note object area (12,12 ', 24,35b, 42,55b, 62b, 72b) radiation that receives, wherein the first label object area quilt Be configured to transmission first wave strong point light (A, B), it is described second label object area be configured as transmission second wave length at light (C, D);And
Analytic unit (6) is used for according to the spy from the first label object area and from the second label object area What is measured radiates to determine the vital sign information (7) of the object.
14. the method for vital sign information (7) of the one kind for determining object (100), includes the following steps:
Detect the first mark from the marker (10,10 ', 30,40,50,60,70) for the skin (104) for being applied to the object Remember object area (11,11 ', 23,34b, 41,54b, 61b, 71b and second label object area (12,12 ', 24,35b, 42,55b, 62b, 72b) radiation that receives, wherein the first label object area is configured as the light (A, B) of transmission first wave strong point, The second label object area is configured as the light (C, D) at transmission second wave length, and
According to the radiation detected from the first label object area and from the second label object area to determine State the vital sign information of object.
15. a kind of non-transient computer-readable storage media, wherein the computer program including program code unit is stored, institute It states program code unit and is wanted according to right for the computer program season computer execution ought to be executed on computers The step of seeking the method described in 14.
CN201480007177.2A 2013-02-05 2014-02-04 System and method for the vital sign information for determining object CN104981200B (en)

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