CN104981172A - Liquid nutrition composition - Google Patents
Liquid nutrition composition Download PDFInfo
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- CN104981172A CN104981172A CN201480005880.XA CN201480005880A CN104981172A CN 104981172 A CN104981172 A CN 104981172A CN 201480005880 A CN201480005880 A CN 201480005880A CN 104981172 A CN104981172 A CN 104981172A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/66—Proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
This liquid nutrition composition contains at least a protein, a lipid, a carbohydrate, a vitamin, and a mineral, 1) the energy value of the composition is at least 1.5 kcal/mL, (2) the protein comprises a whole milk protein and casein as primary components thereof and does not include animal protein degradation products and plant protein degradation products, (3) the amount of the whole milk protein in the protein is greater than the amount of casein, (4) the content of the lipid in the composition is no more than 29% in terms of energy ratio, and (5) at least magnesium and calcium are included as minerals.
Description
Technical field
The present invention relates to aqueous alimentation composition, in more detail, relate to the aqueous alimentation composition of oral administration or the high concentration through pipe administration.
Background technology
There is various factors to make the People of the patient before and after operation, usually eating difficulties or needing the people of nurse to spend healthy life, especially nutrition is sixty-four dollar question.This Nutrition Management is undertaken by the administration of alimentation composition, and alimentation composition is undertaken adjusting (such as with reference to patent document 1) by the balanced mode containing nutritional labelings such as protein, lipid, carbohydrate, vitamin, mineral matters.In addition, this alimentation composition adjusts calorie to keep energy balance.And, as administering mode, oral administration or intranasal, gastrostomy etc. generally can be enumerated through pipe administration.
The calorie adjustment of alimentation composition can adjust high calorie by the content of adjustment lipid, protein, carbohydrate usually.At present, energy value be 1.0kcal/mL consist of main flow, but in recent years, the alimentation composition formed being about 1.5kcal/mL by various energy value is proposed.As the high calorie alimentation composition that energy value is more than 1.5kcal/mL, such as, propose the aqueous alimentation composition recorded in patent document 2,3.
In the administration of alimentation composition, long administration for by administration person along with larger misery, if the alimentation composition that energy value is higher, then can suppress dosage, can alleviate by the burden of administration person, therefore can carry out efficient nutritional supplementation.
At first technical literature
Patent document
Patent document 1: Japanese Unexamined Patent Publication 2004-97119 publication
Patent document 2: Japanese Unexamined Patent Publication 8-196236 publication
Patent document 3: Japan's No. 3445087 publication
Summary of the invention
The technical problem that will solve is intended in invention
Compared with protein, carbohydrate, lipid improves every 1mL calorie for not improving solid content constituent concentration is comparatively useful, if but excessive cooperation lipid, then sometimes MHLW formulate the protein in " Japanese's diet regimen standard (version in 2010) " (Heisei on May 29th, 21), lipid, carbohydrate balance be destroyed.
Manage through pipe nutrition time, use the aqueous alimentation composition of about 900kcal ~ 1000kcal energy such as every day.If this energy value is the common alimentation composition of 900kcal ~ 1000kcal, then the content of vitamin, mineral matter etc. does not reach the standard volume/recommended amounts of Japanese's diet regimen standard (version in 2010), therefore, alimentation composition must be prepared in addition.
If want to make the mineral matter such as magnesium or calcium in a product sufficient, then likely formulation viscosity increases, when oral administration, throat is deteriorated by property, when through pipe administration, Bottomhole pressure is deteriorated, and two kinds of administration routes have the tendency that administration time is increased in result.In addition, if the amount of magnesium or calcium is excessive, then with protein bound, the situation of condensing in alimentation composition, precipitating is had.
In view of the above problems, the object of the present invention is to provide a kind of aqueous alimentation composition, even if this aqueous alimentation composition in order to can absorb need intake vitamin, mineral matter and make high concentrate formulation time, also the rising of viscosity can be suppressed, improve the throat property passed through during oral administration, Bottomhole pressure when pipe administration, and be high caloric aqueous alimentation composition.
For the technological means of dealing with problems
The present inventor concentrates on studies repeatedly, if the viscosity that result is conceived to preparation when lipid amount increases the mineral matter such as magnesium or calcium at least increases, and find, in order to keep this balance, and use total milk protein and casein as the main component of protein, and make the amount of total milk protein in protein more than caseic amount, thus above-mentioned problem can be solved, complete the present invention.
That is, the present invention is as described below.
[1] an aqueous alimentation composition, is characterized in that, containing protein, lipid, carbohydrate, vitamin and mineral matter, and has following 1) ~ 5) feature:
1) energy value of composition is more than 1.5kcal/mL;
2) described protein comprises total milk protein and casein, but does not comprise animal protein analyte and vegetable protein analyte;
3), in described protein, the quality of described total milk protein is greater than described caseic quality;
4) content of the described lipid in composition counts less than 29% with energy Ratios; And
5) as described mineral matter, at least containing magnesium and calcium.
[2] the aqueous alimentation composition as described in above-mentioned [1], wherein, the ratio of above-mentioned casein and above-mentioned total milk protein counts 1:1.1 ~ 1:13 with the mass ratio of protein.
[3] the aqueous alimentation composition as described in above-mentioned [1] or [2], wherein, in the composition of every 900kcal energy, containing above-mentioned more than calcium 650mg and above-mentioned more than magnesium 296mg.
[4] the aqueous alimentation composition according to any one of above-mentioned [1] to [3], wherein, above-mentioned total milk protein is lactoprotein concentrate.
[5] the aqueous alimentation composition according to any one of above-mentioned [1] to [4], wherein, above-mentioned energy value is 1.5 ~ 2.0kcal/mL.
[6] the aqueous alimentation composition according to any one of above-mentioned [1] to [5], wherein, in composition, the content of above-mentioned protein and above-mentioned carbohydrate is respectively 8 ~ 30% and 50 ~ 69% in energy Ratios.
[7] the aqueous alimentation composition according to any one of above-mentioned [1] to [6], wherein, containing phosphorus, and the mass ratio of calcium and phosphorus (Ca/P) is more than 0.74.
Invention effect
Aqueous alimentation composition of the present invention uses total milk protein and casein as protein, and the quality of the total milk protein in protein is set to is greater than caseic quality, therefore viscosity is not made to increase, and the content of lipid is such as set to less than 30% in energy value, is specifically set to less than 29%, even if increase the content of the mineral matter such as magnesium or calcium, the rising of viscosity also can be suppressed.Therefore, can high concentration be made and balancing energy, the aqueous alimentation composition of vitamin when absorbing 900kcal, more than standard volume/recommended amounts containing Japanese's diet regimen standard (version in 2010), mineral matter.In addition, because energy value is adjusted to more than 1.5kcal/mL by aqueous alimentation composition of the present invention, therefore can reduce intake, can administration time be shortened, therefore can alleviate by the burden of administration person.
And, aqueous alimentation composition of the present invention is except protein, lipid and mineral matter, also balancedly can coordinate carbohydrate, vitamin, other any compositions, PFC ratio (component ratio of protein, lipid and carbohydrate) can be made fully close to ideal value.
Detailed description of the invention
Below, the present invention is further described.It should be noted that, in the present invention, what is called is aqueous refers to the state with mobility, specifically, refers to that the viscosity of less than 20 DEG C is the fluid of below 50mPas.
Aqueous alimentation composition of the present invention contains protein, lipid (lipid), carbohydrate, vitamin and mineral matter, and, 1) energy value is more than 1.5kcal/mL; 2) above-mentioned protein comprises total milk protein and casein, not containing animal protein analyte and vegetable protein analyte; 3), in above-mentioned protein, the quality of above-mentioned total milk protein is greater than above-mentioned caseic value quality; 4) energy ratio of the lipid in composition is less than 29%, and, 5) at least containing magnesium and calcium as mineral matter.
As total milk protein, can enumerate: skimmed milk power, comprehensive lactoprotein etc. after the concentrate of full milk itself, full milk, the protein be made up of full milk, skimmed milk, skimmed milk concentrate, lactoprotein concentrate, removing lactose, wherein, preferably lactoprotein concentrate is used.
As casein (casein, also known as casein), can enumerate: with well-established law isolated lactic acid from milk coagulate casein, salt acid cure casein, sulfuric acid coagulates the acid cure casein such as casein or their mixture; Comprise the metal and caseic compound etc. of the caseinates such as casein-sodium.
It should be noted that, in the present invention, not containing animal protein analyte and vegetable protein analyte.Animal protein analyte and vegetable protein analyte are the material utilizing acid or enzyme to be obtained by breaks down proteins, due to favorable dispersibility, therefore also alimentation composition can be used as, if but excessive interpolation, then flavoursome variation, orally ingestible become difficult situation, therefore, these animal protein analytes and vegetable protein analyte is not used in the present invention.
In the present invention, in protein, total milk protein content is more than casein.According to this structure, can by coordinating calcium with the form of protein bound, and, casein can be utilized to combine free magnesium, calcium thus magnesium, calcium containing high concentration.Thus, even if the content of the lipid in aqueous alimentation composition is set as counting less than 29% with energy Ratios, increases the mineral quality such as magnesium or potassium, the viscosity of aqueous alimentation composition also can be suppressed to rise.Therefore, throat in oral administration can be improved by property and the Bottomhole pressure in pipe administration.
The ratio of above-mentioned casein and above-mentioned total milk protein, in the mass ratio of protein, is preferably 1:1.1 ~ 1:13, is more preferably 1:1.1 ~ 1:4.28, more preferably 1:1.1 ~ 1:2.72.If total milk protein is more than casein, then can obtain the viscosity inhibition of aqueous alimentation composition fully, therefore preferably.In addition, if the quality of total milk protein is caseic less than 13 times, then the viscosity of aqueous alimentation composition can be suppressed to rise, therefore preferably.
The content of the protein in aqueous alimentation composition, in energy Ratios, is preferably 8 ~ 30%, is more preferably 13 ~ 19%.If the content of protein is in energy Ratios outside the scope of 8 ~ 30%, the situation of the nutrient balance variation of the PFC ratio of Ze You MHLW diet regimen standard, therefore, is preferably set to 8 ~ 30%.It should be noted that, energy Ratios calculates with 4kcal/g.
As long as the lipid used in the present invention usually Orally-administrable or through pipe administration, is not particularly limited.Such as, can enumerate: soybean oil, perilla oil, perilla herb oil, sunflower oil, safflower seed oil, algae oil, rapeseed oil, palm oil, corn oil, beautiful another name for Sichuan Province multitude oil, coconut oil, olive oil, rice bran wet goods vegetative grease; The animal raw fat such as fish oil, butter; MCT (aliphatic acid of neutral fat, medium chain); The polyunsaturated fatty acids etc. such as eicosapentaenoic acid, DHA, linolenic acid, linoleic acid.Lipid can be used alone a kind, also can be mixed with two or more.From the viewpoint of the essential fatty acid of abundance, preferably combinationally use multiple lipid.
The content of the lipid in aqueous alimentation composition counts less than 29% with energy Ratios, is preferably 20 ~ 29%.If the content of lipid counts less than 29% with energy Ratios, then the nutrient balance of PFC ratio becomes good, so preferably.Moreover energy Ratios calculates with 9kcal/g.
As long as the carbohydrate used in the present invention usually Orally-administrable or through pipe administration, is not particularly limited.Such as can enumerate starch, dextrin, lactose, sucrose, glucose, fructose, maltose etc.Carbohydrate can be used alone a kind, also can be mixed with two or more.Wherein, from the viewpoint of effect of the present invention, be preferably dextrin.
The content of the carbohydrate in aqueous alimentation composition is determined by the use level of protein and lipid, and use level can be suitable for changing, but preferably counts 50 ~ 69% with energy Ratios.If the content of carbohydrate counts more than 50% with energy Ratios, be then easily adjusted to low viscosity and high caloric preparation, therefore preferably, if be less than 69%, then the nutrient balance of PFC ratio becomes good, therefore preferably.It should be noted that, energy Ratios calculates with 4kcal/g.
Vitamin used in the present invention can be enumerated: vitamin A, vitamin D, vitamin E, vitamin K, Cobastab
1, Cobastab
2, nicotinic acid, Cobastab
6, Cobastab
12, folic acid, pantothenic acid, biotin and vitamin C etc., as long as containing more than a kind in these vitamins, preferably all contain.In addition, as mineral matter, can enumerate: calcium, magnesium, phosphorus, iron, zinc, copper, manganese, iodine, selenium, chromium and molybdenum etc., at least containing magnesium and calcium, preferably contain the whole of these mineral matters.
The mode in " Japanese's diet regimen standard (version in 2010) " (Heisei on May 29th, 21) that these vitamins and mineral matter are formulated with applicable MHLW is suitable to be coordinated.
In aqueous alimentation composition of the present invention, such as, when the energy specification of each product of setting is 900kcal, more than magnesium 296mg/900kcal can be added, be preferably more than 310mg/900kcal, be more preferably more than 370mg/900kcal.If coordinate more than magnesium 310mg/900kcal, then meet the presumption average requirement of diet regimen standard, therefore preferably, if be configured in the mode reaching more than 370mg/900kcal, then can meet the recommended amounts of diet regimen standard, therefore more preferably.In addition, calcium can more than 650mg/900kcal, be preferably 650 ~ 2300mg/900kcal, be more preferably 800 ~ 1150mg/900kcal scope in coordinate.If coordinate calcium with more than 650mg/900kcal, then meet the presumption average requirement of diet regimen standard, therefore preferably, if coordinated in the mode reaching more than 800mg/900kcal, then can meet the recommended amounts of diet regimen standard, therefore more preferably.Particularly, when coordinating calcium in the scope of below 1150mg/900kcal, even if such as every day is when absorbing energy 1800kcal, also tolerance upper limit amount can not be exceeded, therefore preferably, when coordinating in the mode reaching 800mg/900kcal, the calcium of picked-up recommended amounts when absorbing 900kcal, even if picked-up 1800kcal, to the tolerance upper limit, also there is affluence, therefore also can absorb other food.
In addition, preferably the content of other vitamins and mineral matter also can make the picked-up recommended amounts recorded in MHLW's diet regimen standard or standard volume sufficient.Such as, for adult's picked-up of a day of more than 18 years old, the recommended amounts/standard volume of the picked-up of each composition was: vitamin A 850 ~ 2700 μ gRE, vitamin D 5.5 ~ 50 μ g, vitamin E 7.0 ~ 650mg, vitamin K 75 more than μ g, Cobastab
1more than 1.4mg, Cobastab
2more than 1.6mg, nicotinic acid (niacinamide) 15 ~ 250mg, Cobastab
61.4 ~ 40mg, Cobastab
122.4 more than μ g, folic acid 240 ~ 1300 μ g, more than pantothenic acid 6mg, biotin 50 more than μ g, vitamin C more than 100mg, phosphorus 1000 ~ 3000mg, iron 11.0 ~ 40mg, zinc 12 ~ 30mg, manganese 4.0 ~ 11mg, copper 0.9 ~ 10mg, iodine 130 ~ 2200 μ g, selenium 30 ~ 210 μ g, chromium 40 more than μ g, molybdenum 30 ~ 450 μ g, if coordinate vitamin A 850 ~ 1350 μ gRE, vitamin D 5.5 ~ 25 μ g, vitamin E 7.0 ~ 325mg, vitamin K 75 more than μ g, Cobastab relative to the every 900kcal of energy value
1more than 1.4mg, Cobastab
2more than 1.6mg, nicotinic acid (niacinamide) 15 ~ 125mg, Cobastab
61.4 ~ 20mg, Cobastab
122.4 more than μ g, folic acid 240 ~ 650 μ g, more than pantothenic acid 6mg, biotin 50 more than μ g, vitamin C more than 100mg, phosphorus 1000 ~ 1500mg, iron 11.0 ~ 20mg, zinc 12 ~ 15mg, manganese 4.0 ~ 5.5mg, copper 0.9 ~ 5mg, iodine 130 ~ 1100 μ g, selenium 30 ~ 105 μ g, chromium 40 more than μ g, molybdenum 30 ~ 225 μ g, even if when then absorbing 1800kcal, also can not exceed the tolerance upper limit of MHLW's diet regimen standard, be therefore desirable.Contain vitamin and mineral matter in the mode of applicable MHLW diet regimen standard, thus necessary whole nutrition in one day can be absorbed by a product.
It should be noted that, likely occur that potassium is at blood level rising trend, therefore, be preferably set to lower than diet regimen standard (JJPEN.Vol.19 No.6,1997, p567-633) from the viewpoint of security.
The concentration of sodium with salt conversion minimal requirement for 1.5g, when needing to there is salt restriction because of hypertension, lower than 6g, even if be therefore preferably set to when absorbing supposition maximal oxygen taken amount 1800kcal, working as gauge maximum with salt is also below 5g (Treatment Guidelines for Hypertension version in 2009).
In aqueous alimentation composition of the present invention, the mass ratio (Ca/P) of calcium and phosphorus is preferably more than 0.74.If Ca/P is more than 0.74, then, compared with situation about coordinating less than 0.74, bone density significantly improves, therefore preferably (Japanese's diet regimen standard (version in 2010), P202).
It should be noted that, aqueous alimentation composition of the present invention also can add the salts such as emulsifying agent, phosphate, citrate, fruit juice, spices etc. as required.
The energy value of aqueous alimentation composition of the present invention is more than 1.5kcal/mL, is preferably 1.5 ~ 2.0kcal/mL, more preferably 1.5 ~ 1.75kcal/mL.Energy value can adjust in the scope of the energy Ratios of above-mentioned various composition.
Aqueous alimentation composition of the present invention, except above-mentioned protein, lipid, carbohydrate, vitamin and mineral matter and other components, also needs water.By being mixed with these compositions by water, thus obtain the alimentation composition with mobility.
In the present invention, water is not particularly limited with the mixing ratio of the composition being mixed in this water, when absorbing 900kcal, more than standard volume/the recommended amounts containing Japanese's diet regimen standard (version in 2010) vitamin, mineral matter, and when being prepared in the mode that energy value reaches more than 1.5kcal/mL, as long as make the viscosity at 20 DEG C be below 50mPas.
Aqueous alimentation composition of the present invention such as can be prepared as follows.
(1) in protein, carbohydrate, mineral matter, add appropriate water, and mix, make liquid material, in this liquid material, add lipid, emulsifying agent as required, and mix, prepare aqueous alimentation composition of the present invention.
(2) Xiang Shuizhong adds appropriate protein, carbohydrate, mineral matter, prepares aqueous alimentation composition of the present invention.
It should be noted that, the mixed method of each composition and order by merging are arbitrary, are not particularly limited.
The of the present invention aqueous alimentation composition prepared in this manner does not condense or precipitates, and the viscosity at 20 DEG C is adjusted to below 50mPas, is preferably the scope of 8 ~ 30mPas.Therefore, throat when can improve oral administration, by property, in addition, improves the Bottomhole pressure when pipe administration, can reduce administration time.It should be noted that, in the present invention, so-called viscosity refers to, utilizes the method specified in the Japanese Pharmacopoeia ordinary test method <2.53> viscosimetry revised for the 16 time to carry out measuring and the value obtained.
Aqueous alimentation composition of the present invention provides the composition after pasteurization usually.As long as the method for pasteurization is according to well-established law, be not particularly limited.It should be noted that, as container, the duplexer etc. of known soft synthetic resin, paper and metal forming can be enumerated.
Embodiment
Below, by embodiment and comparative example, the present invention is further described, but the present invention is not by the restriction of following example.
(embodiment 1)
Use the warm water of 40 ~ 60 DEG C of 5L, take the mass ratio of lactoprotein concentrate and casein-sodium as the value recorded in table 1, energy Ratios is the value recorded in table 1, and magnesium (Mg) amount and calcium (Ca) amount are the mode of the value recorded in table 1, add lactoprotein concentrate (protein content 80%) 567g as total milk protein successively, as caseic casein-sodium (protein content 90%) 40g, lipid 420g, as the dextrin 2330g of carbohydrate, as vitamin and the mineral mixture of the following combination of vitamin and mineral matter, TK homogeneous mixer is used to mix.Finally, add warm water (40 ~ 60 DEG C), adjust to 10L.
Vitamin and mineral mixture use following mixture: every 900kcal, vitamin A 850 μ gRE, Cobastab
11.4mg, Cobastab
21.6mg, Cobastab
61.4mg, Cobastab
122.4 μ g, vitamin D 5.5 μ g, vitamin E 7.0mg, vitamin C 100mg, niacin hydroxyacyl amine 15.0mg, pantothenic acid 6.0mg, folic acid 240 μ g, vitamin K 75 μ g, biotin 50.0 μ g, calcium 800mg, magnesium 370mg, phosphorus 1081mg, iron 11.0mg, zinc 12.0mg, copper 0.9mg, manganese 4.0mg, iodine 13.0 μ g, selenium 30.0 μ g, chromium 40.0 μ g, molybdenum 30.0 μ g.
By the energy value of prepared aqueous alimentation composition, total milk protein (with protein gauge) and caseic amount ratio (with protein gauge), the energy Ratios of gross protein, lipid and carbohydrate, magnesium (Mg) measures and calcium (Ca) measures and Ca/P is shown in table 1.
For the aqueous alimentation composition of embodiment 1, confirm, result to estimate, cohesion or precipitation, be not the composition with the advantage being easy to drink.
(embodiment 2 ~ 21)
The value that the energy Ratios of value, protein, lipid and the carbohydrate recorded for table 1 with total milk protein and caseic mass ratio is recorded for table 1 and magnesium (Mg) is measured and calcium (Ca) measures the value, the further Ca/P that become table 1 and record than the mode of the value recorded for table 1, change the use level of each composition, in addition, prepare similarly to Example 1.It should be noted that, in embodiment 18 ~ 21, take phosphorus as 999mg, selenium is 50.04 μ g, mode that vitamin D is 15 μ g coordinates each composition, in embodiment 18, be that the mode of 2.24mg coordinates each composition with vitamin E, in embodiment 19 ~ 21, take vitamin E as 1.503mg, mode that vitamin C is 200mg coordinates each composition, in embodiment 21, with Cobastab
12be that the mode of 4.5 μ g coordinates each composition.
For the aqueous alimentation composition of embodiment 2 ~ 21, confirm, result to estimate, cohesion or precipitation, be not the composition with the advantage being easy to drink.
(comparative example 1,2)
The value recorded for table 1 for the energy Ratios of value, protein, lipid and carbohydrate recorded in table 1 with total milk protein and caseic mass ratio and magnesium (Mg) and calcium (Ca) measure value for recording in table 1, further, Ca/P is than the mode of the value for recording in table 1, change the use level of each composition, in addition, prepare similarly to Example 1.
The aqueous alimentation composition of comparative example 1,2 is the high and compositions not easily drunk of viscosity.
(comparative example 3)
In the warm water (60 DEG C) of 70.90L, add lactoprotein concentrate mix using albumen gauge 1800g, the succinylated monoglyceride 220g as emulsifying agent, the dextrin 26420g as carbohydrate, use TK homogeneous mixer with albumen gauge 1800g, caseinolytic thing with albumen gauge 3600g, casein-sodium.
In the liquid material obtained, add corn oil 7090g, the vitamin of following composition and mineral mixture, use TK homogeneous mixer to carry out pre-emulsification, add water so that total amount is adjusted to 100L.Use high pressure homogenisers to above-mentioned emulsion repeatedly carry out 5 first stage 5MPa, second stage 50MPa two benches process and make it to homogenize.
Vitamin and mineral mixture use following mixture: vitamin A 250000IU, Cobastab
1150mg, Cobastab
2220mg, Cobastab
6370mg, Cobastab
12120mg, vitamin D
320000IU, vitamin E 7500IU, vitamin C 10g, niacin hydroxyacyl amine 2000mg, calcium pantothenate 1000mg, folic acid 3000mg, sodium chloride 77g, potassium chloride 150g, magnesium carbonate 158g, ironic citrate 14g.
The aqueous alimentation composition of comparative example 3 is that viscosity is low and be easy to the composition drunk.
(comparative example 4)
In comparative example 3, the calcium in every 900kcal is set to 800mg, magnesium is set to 370mg, in addition, prepare in the same manner as comparative example 3.
The aqueous alimentation composition of comparative example 4 is the compositions producing a large amount of condensation product and cannot homogenize.
(comparative example 5)
In comparative example 3, use lactoprotein concentrate as total milk protein, and use calcium caseinate (using proteinometer 1800g) as casein, in addition, prepare in the same manner as comparative example 3.
The aqueous alimentation composition of comparative example 5 is the composition being condensed into gel/pudding-like.
(comparative example 6)
In comparative example 5, the calcium in every 900kcal is set to 800mg, magnesium is set to 370mg, in addition, prepare in the same manner as comparative example 5.
The aqueous alimentation composition of comparative example 6 is the compositions being condensed into gel/pudding-like.
< viscosity evaluates >
After the aqueous alimentation composition of the embodiment 1 ~ 17 of above-mentioned preparation and comparative example 1 ~ 3,5,6 is preserved 10 minutes at 20 DEG C, sampling 20mL, use single cylindrical shape rotation viscometer (Vismetron viscosimeter VDA2 type, Zhi Pu Semtek Co., Ltd. manufacture), carry out measuring (revising Japanese Pharmacopoeia ordinary test method <2.53> viscosimetry for the 16 time).
Based on measured viscosity, evaluated by following evaluation criterion.Table 1 will be the results are shown in.
[evaluation criterion]
Below A:30mPas
B: more than 30mPas and below 50mPas
C: more than 50mPas and below 100mPas
D: more than 100mPas
Table 1
Table 1
As shown in Table 1, in embodiment 1 ~ 21, even if energy value is adjusted to more than 1.5kcal/mL and mineral matter is increased to applicable MHLW diet regimen standard, do not find the rising of viscosity yet, and there is good mobility.And known, also do not condense or precipitate, taste is also excellent.
In addition, in embodiment 1 ~ 21, acid cure casein is used to replace casein-sodium and make aqueous alimentation composition.For the aqueous alimentation composition obtained, confirm, result to estimate, cohesion or precipitation, be not the composition with the advantage being easy to drink.
Therefore, according to the present invention, can be made into high concentration and balancing energy, can absorb must the vitamin of intake, the aqueous alimentation composition of mineral matter.
In detail and describe the present invention with reference to specific embodiment, but those skilled in the art should understand and can carry out various change or correction without departing from the spirit and scope of the present invention.The Japanese patent application (special Willing 2013-010202) that the application proposed based on January 23rd, 2013, and its full content is incorporated into this, as a reference.
Industrial applicibility
Aqueous alimentation composition of the present invention is containing the necessary vitamin of intake, the high concentrate formulation of mineral matter, and be high calorie preparation, therefore, to needing by oral administration or carrying out in the field of the patient of nutritional supplementation or the alimentation composition of People administration through pipe administration, can effectively utilize.
Claims (7)
1. an aqueous alimentation composition, is characterized in that, containing protein, lipid, carbohydrate, vitamin and mineral matter, and has following 1) ~ 5) feature:
1) energy value of composition is more than 1.5kcal/mL;
2) described protein comprises total milk protein and casein, but does not comprise animal protein analyte and vegetable protein analyte;
3), in described protein, the quality of described total milk protein is greater than described caseic quality;
4) content of the described lipid in composition counts less than 29% with energy Ratios; And
5) as described mineral matter, at least containing magnesium and calcium.
2. aqueous alimentation composition as claimed in claim 1, is characterized in that, the ratio of described casein and described total milk protein counts 1:1.1 ~ 1:13 with the mass ratio of protein.
3. aqueous alimentation composition as claimed in claim 1 or 2, is characterized in that, in every 900kcal, containing described more than calcium 650mg and described more than magnesium 296mg.
4. the aqueous alimentation composition according to any one of claims 1 to 3, is characterized in that, described total milk protein is lactoprotein concentrate.
5. the aqueous alimentation composition according to any one of Claims 1 to 4, is characterized in that, described energy value is 1.5 ~ 2.0kcal/mL.
6. the aqueous alimentation composition according to any one of Claims 1 to 5, is characterized in that, the described protein in composition and the content of described carbohydrate are respectively 8 ~ 30% and 50 ~ 69% in energy Ratios.
7. the aqueous alimentation composition according to any one of claim 1 ~ 6, is characterized in that, containing phosphorus, and the mass ratio of calcium and phosphorus (Ca/P) is 0.74.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013-010202 | 2013-01-23 | ||
| JP2013010202 | 2013-01-23 | ||
| PCT/JP2014/051265 WO2014115768A1 (en) | 2013-01-23 | 2014-01-22 | Liquid nutrition composition |
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| CN104981172A true CN104981172A (en) | 2015-10-14 |
| CN104981172B CN104981172B (en) | 2017-09-05 |
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| Country | Link |
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| JP (1) | JP5788112B2 (en) |
| KR (1) | KR102069931B1 (en) |
| CN (1) | CN104981172B (en) |
| TW (1) | TWI580362B (en) |
| WO (1) | WO2014115768A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109688842A (en) * | 2016-08-08 | 2019-04-26 | 株式会社明治 | Acid liquid alimentation composition |
| CN110312516A (en) * | 2017-04-26 | 2019-10-08 | 株式会社明治 | Brainwork ability raising composition and cognitive ability raising composition |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6660089B2 (en) * | 2015-03-09 | 2020-03-04 | サントリーホールディングス株式会社 | High energy beverages containing insoluble calcium |
| JP7085704B1 (en) * | 2021-01-28 | 2022-06-16 | イーエヌ大塚製薬株式会社 | Gel-like nutritional composition |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08196236A (en) * | 1995-01-19 | 1996-08-06 | Terumo Corp | Liquid nutritive diet and high-caloric nutrient |
| JPH10210951A (en) * | 1997-01-28 | 1998-08-11 | Morinaga Milk Ind Co Ltd | Liquid diet, and aseptic high calorie liquid diet |
| JPH119187A (en) * | 1997-06-26 | 1999-01-19 | Snow Brand Milk Prod Co Ltd | Nourishing beverage and its production |
| JP2001061444A (en) * | 1999-08-25 | 2001-03-13 | Ajinomoto Co Inc | High-calorie high-protein liquid food |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4063022B2 (en) | 2002-09-11 | 2008-03-19 | 日油株式会社 | Liquid food and beverage composition and food and beverage |
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2014
- 2014-01-22 JP JP2014553571A patent/JP5788112B2/en active Active
- 2014-01-22 KR KR1020157019698A patent/KR102069931B1/en active IP Right Grant
- 2014-01-22 WO PCT/JP2014/051265 patent/WO2014115768A1/en active Application Filing
- 2014-01-22 CN CN201480005880.XA patent/CN104981172B/en active Active
- 2014-01-23 TW TW103102531A patent/TWI580362B/en active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08196236A (en) * | 1995-01-19 | 1996-08-06 | Terumo Corp | Liquid nutritive diet and high-caloric nutrient |
| JPH10210951A (en) * | 1997-01-28 | 1998-08-11 | Morinaga Milk Ind Co Ltd | Liquid diet, and aseptic high calorie liquid diet |
| JPH119187A (en) * | 1997-06-26 | 1999-01-19 | Snow Brand Milk Prod Co Ltd | Nourishing beverage and its production |
| JP2001061444A (en) * | 1999-08-25 | 2001-03-13 | Ajinomoto Co Inc | High-calorie high-protein liquid food |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109688842A (en) * | 2016-08-08 | 2019-04-26 | 株式会社明治 | Acid liquid alimentation composition |
| CN110312516A (en) * | 2017-04-26 | 2019-10-08 | 株式会社明治 | Brainwork ability raising composition and cognitive ability raising composition |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104981172B (en) | 2017-09-05 |
| JP5788112B2 (en) | 2015-09-30 |
| WO2014115768A1 (en) | 2014-07-31 |
| TW201442643A (en) | 2014-11-16 |
| KR20150110536A (en) | 2015-10-02 |
| JPWO2014115768A1 (en) | 2017-01-26 |
| TWI580362B (en) | 2017-05-01 |
| KR102069931B1 (en) | 2020-01-23 |
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